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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chlorocycloalkane
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Accession:CHEBI:39155 term browser browse the term
Definition:A chlorohydrocarbon that is any cycloalkane substituted by at least one chloro group.
Synonyms:related_synonym: chlorocycloalkanes


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alpha-hexachlorocyclohexane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of ABCB4 mRNA CTD PMID:16940010 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of ABCC3 mRNA CTD PMID:17785943 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Acaa2 acetyl-CoA acyltransferase 2 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of ACAA2 mRNA CTD PMID:16940010 NCBI chr18:70,733,872...70,762,395
Ensembl chr18:70,733,872...70,762,395
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of ACAT2 mRNA CTD PMID:17785943 NCBI chr 1:47,972,399...47,992,654
Ensembl chr 1:47,972,399...47,992,653
JBrowse link
G Adap2 ArfGAP with dual PH domains 2 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of ADAP2 mRNA CTD PMID:16940010 NCBI chr10:67,494,851...67,527,582
Ensembl chr10:67,494,984...67,526,426
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of ADH1 mRNA CTD PMID:16940010 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of ALDH1A1 mRNA CTD PMID:17785943 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Apoc1 apolipoprotein C1 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of APOC1 mRNA CTD PMID:16940010 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G App amyloid beta precursor protein increases expression EXP alpha-hexachlorocyclohexane results in increased expression of APP mRNA CTD PMID:17785943 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor multiple interactions ISO alpha-hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; alpha-hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; alpha-hexachlorocyclohexane inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:10696776 PMID:15084347 PMID:21962538 PMID:26022396 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Ca3 carbonic anhydrase 3 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of CA3 mRNA CTD PMID:16940010 PMID:17785943 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CA2 mRNA CTD PMID:17785943 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp3 caspase 3 increases activity ISO alpha-hexachlorocyclohexane results in increased activity of CASP3 protein CTD PMID:19818741 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions
increases activity
EXP [Hexachlorocyclohexane co-treated with alpha-hexachlorocyclohexane co-treated with beta-hexachlorocyclohexane co-treated with delta-hexachlorocyclohexane] results in increased activity of CAT protein
alpha-hexachlorocyclohexane results in increased activity of CAT protein
CTD PMID:1708174 PMID:16046044 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbx1 chromobox 1 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of CBX1 mRNA CTD PMID:16940010 NCBI chr10:84,656,698...84,677,112
Ensembl chr10:84,669,914...84,675,741
JBrowse link
G Cd36 CD36 molecule increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CD36 mRNA CTD PMID:17785943 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdc123 cell division cycle 123 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CDC123 mRNA CTD PMID:16940010 NCBI chr17:76,410,629...76,454,275
Ensembl chr17:76,410,585...76,454,282
JBrowse link
G Cdk17 cyclin-dependent kinase 17 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of CDK17 mRNA CTD PMID:16940010 NCBI chr 7:34,001,506...34,088,418
Ensembl chr 7:34,001,506...34,079,616
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CES2 mRNA CTD PMID:17785943 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 affects expression
decreases expression
increases expression
EXP alpha-hexachlorocyclohexane affects the expression of CHCHD2 mRNA
alpha-hexachlorocyclohexane results in decreased expression of CHCHD2 mRNA
alpha-hexachlorocyclohexane results in increased expression of CHCHD2 mRNA
CTD PMID:16940010 NCBI chr 9:101,388,148...101,388,819
Ensembl chr 9:101,388,151...101,388,833
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression
increases expression
decreases expression
EXP alpha-hexachlorocyclohexane affects the expression of CPN1 mRNA
alpha-hexachlorocyclohexane results in increased expression of CPN1 mRNA
alpha-hexachlorocyclohexane results in decreased expression of CPN1 mRNA
CTD PMID:16940010 NCBI chr 1:263,733,887...263,762,758
Ensembl chr 1:263,733,519...263,762,785
JBrowse link
G Ctsc cathepsin C decreases expression
increases expression
affects expression
EXP alpha-hexachlorocyclohexane results in decreased expression of CTSC mRNA
alpha-hexachlorocyclohexane results in increased expression of CTSC mRNA
alpha-hexachlorocyclohexane affects the expression of CTSC mRNA
CTD PMID:16940010 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Cyb5a cytochrome b5 type A affects expression EXP alpha-hexachlorocyclohexane affects the expression of CYB5A mRNA CTD PMID:17785943 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cyb5r3 cytochrome b5 reductase 3 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CYB5R3 mRNA CTD PMID:17785943 NCBI chr 7:124,024,003...124,041,564
Ensembl chr 7:124,023,995...124,041,594
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP1A1 protein CTD PMID:11165752 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions EXP [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP2A1 protein CTD PMID:16246485 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases activity
EXP [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP2B1 protein; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2B1 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2B1 protein
alpha-hexachlorocyclohexane results in increased activity of CYP2B1 protein
CTD PMID:1372805 PMID:11165752 PMID:16246485 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CYP2B15 mRNA CTD PMID:17785943 NCBI chr 1:251,325,923...251,338,404
Ensembl chr 1:251,325,923...251,338,358
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CYP2B2 mRNA CTD PMID:16940010 PMID:17785943 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C11 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C11 protein CTD PMID:16246485 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of CYP2C12 mRNA CTD PMID:17785943 NCBI chr 1:258,709,726...258,766,873
Ensembl chr 1:258,709,721...258,766,881
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases expression
multiple interactions
EXP alpha-hexachlorocyclohexane results in increased expression of CYP2C6V1 mRNA
[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2C6V1 protein
CTD PMID:16246485 PMID:16940010 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP2E1 protein CTD PMID:16246485 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
EXP alpha-hexachlorocyclohexane results in increased expression of CYP3A2 mRNA
[Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in decreased expression of CYP3A2 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased activity of CYP3A2 protein; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP3A2 mRNA; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP3A2 protein
CTD PMID:11165752 PMID:16246485 PMID:16940010 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CYP3A23-3A1 mRNA CTD PMID:16940010 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CYP4A8 mRNA CTD PMID:17785943 NCBI chr 5:133,978,953...134,008,255
Ensembl chr 5:133,978,954...134,008,255
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of CYP51 mRNA CTD PMID:17785943 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 decreases expression
increases expression
affects expression
EXP alpha-hexachlorocyclohexane results in decreased expression of ECI1 mRNA
alpha-hexachlorocyclohexane results in increased expression of ECI1 mRNA
alpha-hexachlorocyclohexane affects the expression of ECI1 mRNA
CTD PMID:16940010 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Egf epidermal growth factor multiple interactions EXP [EGF protein co-treated with alpha-hexachlorocyclohexane] results in increased expression of MYC mRNA CTD PMID:12632255 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Epcam epithelial cell adhesion molecule increases expression EXP alpha-hexachlorocyclohexane results in increased expression of EPCAM mRNA CTD PMID:17785943 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
increases activity
EXP alpha-hexachlorocyclohexane results in increased expression of EPHX1 mRNA
alpha-hexachlorocyclohexane results in increased activity of EPHX1 protein
CTD PMID:1372805 PMID:16940010 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
EXP
ISO
alpha-hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR1 protein]
alpha-hexachlorocyclohexane results in increased activity of ESR1 protein
CTD PMID:10580743 PMID:26022396 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO alpha-hexachlorocyclohexane results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of FEV mRNA CTD PMID:17785943 NCBI chr 9:82,142,981...82,146,855
Ensembl chr 9:82,142,981...82,146,874
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases response to substance EXP alpha-hexachlorocyclohexane results in decreased susceptibility to FGF1 protein CTD PMID:1715812 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fkbp3 FKBP prolyl isomerase 3 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of FKBP3 mRNA CTD PMID:17785943 NCBI chr 6:86,810,865...86,822,115
Ensembl chr 6:86,810,809...86,822,094
JBrowse link
G Fn1 fibronectin 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of FN1 mRNA CTD PMID:17785943 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP alpha-hexachlorocyclohexane inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS mRNA] CTD PMID:1380685 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Ftl1 ferritin light chain 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of FTL1 mRNA CTD PMID:16940010 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression
multiple interactions
EXP
ISO
alpha-hexachlorocyclohexane results in decreased expression of GABRA1 mRNA
alpha-hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD PMID:9316872 PMID:17785943 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 multiple interactions ISO alpha-hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] CTD PMID:9316872 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO alpha-hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; alpha-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] CTD PMID:9316872 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression
decreases expression
increases expression
EXP alpha-hexachlorocyclohexane affects the expression of GAPDH mRNA
alpha-hexachlorocyclohexane results in decreased expression of GAPDH mRNA
alpha-hexachlorocyclohexane results in increased expression of GAPDH mRNA
CTD PMID:16940010 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of GPX2 mRNA CTD PMID:17785943 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gsr glutathione-disulfide reductase increases expression
multiple interactions
EXP alpha-hexachlorocyclohexane results in increased expression of GSR mRNA
[Hexachlorocyclohexane co-treated with alpha-hexachlorocyclohexane co-treated with beta-hexachlorocyclohexane co-treated with delta-hexachlorocyclohexane] results in increased activity of GSR protein
CTD PMID:16046044 PMID:17785943 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of GSTA2 mRNA CTD PMID:16940010 PMID:17785943 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of GSTA5 mRNA CTD PMID:17785943 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of GSTK1 mRNA CTD PMID:16940010 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G Gstm4 glutathione S-transferase mu 4 decreases expression
increases expression
affects expression
EXP alpha-hexachlorocyclohexane results in decreased expression of GSTM4 mRNA
alpha-hexachlorocyclohexane results in increased expression of GSTM4 mRNA
alpha-hexachlorocyclohexane affects the expression of GSTM4 mRNA
CTD PMID:16940010 NCBI chr 2:210,834,013...210,839,242
Ensembl chr 2:210,833,884...210,839,295
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
EXP [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in decreased expression of GSTP1 protein; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of GSTP1 protein
alpha-hexachlorocyclohexane results in increased expression of GSTP1 mRNA
CTD PMID:16246485 PMID:16940010 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hgf hepatocyte growth factor increases expression EXP alpha-hexachlorocyclohexane results in increased expression of HGF protein CTD PMID:1370768 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of HSPB1 mRNA CTD PMID:17785943 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 affects expression EXP alpha-hexachlorocyclohexane affects the expression of KCNJ5 mRNA CTD PMID:17785943 NCBI chr 8:33,435,493...33,463,410
Ensembl chr 8:33,433,905...33,463,467
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression EXP alpha-hexachlorocyclohexane results in increased expression of KIT mRNA CTD PMID:16940010 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Lpl lipoprotein lipase increases expression EXP alpha-hexachlorocyclohexane results in increased expression of LPL mRNA CTD PMID:17785943 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp2 LDL receptor related protein 2 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of LRP2 mRNA CTD PMID:16940010 NCBI chr 3:55,665,153...55,822,484
Ensembl chr 3:55,665,145...55,822,551
JBrowse link
G Luc7l2 LUC7-like 2 pre-mRNA splicing factor affects expression EXP alpha-hexachlorocyclohexane affects the expression of LUC7L2 mRNA CTD PMID:17785943 NCBI chr 4:66,290,319...66,357,970
Ensembl chr 4:66,290,389...66,354,711
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression
affects expression
decreases expression
EXP alpha-hexachlorocyclohexane results in increased expression of MAPK1 mRNA
alpha-hexachlorocyclohexane affects the expression of MAPK1 mRNA
alpha-hexachlorocyclohexane results in decreased expression of MAPK1 mRNA
CTD PMID:16940010 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of MAPK6 mRNA CTD PMID:16940010 NCBI chr 8:82,328,013...82,351,108
Ensembl chr 8:82,328,020...82,351,108
JBrowse link
G Me1 malic enzyme 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of ME1 mRNA CTD PMID:17785943 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Meox2 mesenchyme homeobox 2 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of MEOX2 mRNA CTD PMID:17785943 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression EXP alpha-hexachlorocyclohexane results in increased expression of COX1 mRNA CTD PMID:16940010 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Muc13 mucin 13, cell surface associated decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of MUC13 mRNA CTD PMID:17785943 NCBI chr11:70,185,757...70,223,012
Ensembl chr11:70,185,757...70,211,701
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions EXP [EGF protein co-treated with alpha-hexachlorocyclohexane] results in increased expression of MYC mRNA CTD PMID:12632255 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [alpha-hexachlorocyclohexane results in increased expression of NCF1 mRNA] CTD PMID:28273962 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ncl nucleolin increases expression EXP alpha-hexachlorocyclohexane results in increased expression of NCL mRNA CTD PMID:17785943 NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions
ISO alpha-hexachlorocyclohexane results in increased expression of NOS3 mRNA
Acetylcysteine inhibits the reaction [alpha-hexachlorocyclohexane results in increased expression of NOS3 mRNA]
CTD PMID:28273962 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of NQO1 mRNA CTD PMID:16940010 PMID:17785943 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO alpha-hexachlorocyclohexane binds to and results in increased activity of NR1I2 protein
alpha-hexachlorocyclohexane results in increased activity of NR1I2 protein
CTD PMID:21115097 PMID:25680588 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions EXP [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of OGG1 mRNA CTD PMID:16246485 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Onecut1 one cut homeobox 1 affects expression EXP alpha-hexachlorocyclohexane affects the expression of ONECUT1 mRNA CTD PMID:17785943 NCBI chr 8:81,765,779...81,799,894
Ensembl chr 8:81,766,041...81,793,577
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in decreased expression of PCNA protein; [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of PCNA protein CTD PMID:16246485 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pgr progesterone receptor multiple interactions ISO alpha-hexachlorocyclohexane inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein] CTD PMID:26022396 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of PPP2R2B mRNA CTD PMID:17785943 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Prss8 serine protease 8 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of PRSS8 mRNA CTD PMID:17785943 NCBI chr 1:199,372,519...199,377,035
Ensembl chr 1:199,372,519...199,377,035
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of PSAT1 mRNA CTD PMID:17785943 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of PSMC3 mRNA CTD PMID:16940010 NCBI chr 3:79,876,938...79,882,319
Ensembl chr 3:79,876,938...79,882,319
JBrowse link
G Psme1 proteasome activator subunit 1 decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of PSME1 mRNA CTD PMID:16940010 NCBI chr15:34,256,071...34,258,947
Ensembl chr15:34,256,071...34,258,947
JBrowse link
G Rab7a RAB7A, member RAS oncogene family increases expression EXP alpha-hexachlorocyclohexane results in increased expression of RAB7 mRNA CTD PMID:17785943 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Rb1 RB transcriptional corepressor 1 affects expression
increases expression
decreases expression
EXP alpha-hexachlorocyclohexane affects the expression of RB1 mRNA
alpha-hexachlorocyclohexane results in increased expression of RB1 mRNA
alpha-hexachlorocyclohexane results in decreased expression of RB1 mRNA
CTD PMID:16940010 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rnpep arginyl aminopeptidase decreases expression
increases expression
affects expression
EXP alpha-hexachlorocyclohexane results in decreased expression of RNPEP mRNA
alpha-hexachlorocyclohexane results in increased expression of RNPEP mRNA
alpha-hexachlorocyclohexane affects the expression of RNPEP mRNA
CTD PMID:16940010 NCBI chr13:52,092,863...52,124,006
Ensembl chr13:52,092,859...52,111,363
JBrowse link
G Rplp0 ribosomal protein lateral stalk subunit P0 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of RPLP0 mRNA CTD PMID:16940010 NCBI chr12:46,791,528...46,794,797
Ensembl chr12:46,791,528...46,794,797
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of SCD1 mRNA CTD PMID:17785943 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Slc16a1 solute carrier family 16 member 1 affects expression
increases expression
decreases expression
EXP alpha-hexachlorocyclohexane affects the expression of SLC16A1 mRNA
alpha-hexachlorocyclohexane results in increased expression of SLC16A1 mRNA
alpha-hexachlorocyclohexane results in decreased expression of SLC16A1 mRNA
CTD PMID:16940010 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc17a1 solute carrier family 17 member 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of SLC17A1 mRNA CTD PMID:17785943 NCBI chr17:43,473,048...43,504,645 JBrowse link
G Smpx small muscle protein, X-linked decreases expression EXP alpha-hexachlorocyclohexane results in decreased expression of SMPX mRNA CTD PMID:17785943 NCBI chr  X:40,029,200...40,086,870
Ensembl chr  X:40,030,248...40,086,870
JBrowse link
G Snx4 sorting nexin 4 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of SNX4 mRNA CTD PMID:17785943 NCBI chr11:70,693,381...70,753,620
Ensembl chr11:70,693,366...70,753,632
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO alpha-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; alpha-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein] CTD PMID:10993823 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Suclg2 succinate-CoA ligase GDP-forming subunit beta increases expression EXP alpha-hexachlorocyclohexane results in increased expression of SUCLG2 mRNA CTD PMID:16940010 NCBI chr 4:127,552,100...127,824,970
Ensembl chr 4:127,552,101...127,824,970
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of SULT1B1 mRNA CTD PMID:16940010 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Tp53 tumor protein p53 increases expression
affects expression
decreases expression
EXP alpha-hexachlorocyclohexane results in increased expression of TP53 mRNA
alpha-hexachlorocyclohexane affects the expression of TRP53 mRNA
alpha-hexachlorocyclohexane results in decreased expression of TP53 mRNA
CTD PMID:16940010 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ubc ubiquitin C increases expression EXP alpha-hexachlorocyclohexane results in increased expression of UBC mRNA CTD PMID:16940010 NCBI chr12:36,638,457...36,642,734
Ensembl chr12:36,638,457...36,642,734
JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of UGT1A5 mRNA CTD PMID:17785943 NCBI chr 9:95,274,707...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of UGT1A6 mRNA CTD PMID:17785943 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C increases expression EXP alpha-hexachlorocyclohexane results in increased expression of UGT1A7 mRNA CTD PMID:16940010 NCBI chr 9:95,233,957...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of UGT2A1 mRNA CTD PMID:16940010 NCBI chr14:22,192,970...22,217,094 JBrowse link
G Ugt2b UDP glycosyltransferase 2 family, polypeptide B increases expression EXP alpha-hexachlorocyclohexane results in increased expression of UGT2B mRNA CTD PMID:16940010 Ensembl chr14:22,375,955...22,534,720 JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP alpha-hexachlorocyclohexane results in increased expression of UGT2B1 mRNA CTD PMID:16940010 PMID:17785943 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vip vasoactive intestinal peptide multiple interactions EXP alpha-hexachlorocyclohexane inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP] CTD PMID:2467674 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
beta-hexachlorocyclohexane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of ABCA1 mRNA CTD PMID:25270620 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 increases expression ISO beta-hexachlorocyclohexane results in increased expression of ABCB11 mRNA CTD PMID:28392238 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO beta-hexachlorocyclohexane results in increased expression of ABCC2 mRNA CTD PMID:28392238 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression ISO beta-hexachlorocyclohexane results in increased expression of ABCC3 mRNA CTD PMID:28392238 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of ABCG1 mRNA CTD PMID:25270620 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO beta-hexachlorocyclohexane results in increased expression of ABCG8 mRNA; beta-hexachlorocyclohexane results in increased expression of ABCG8 protein CTD PMID:27203212 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of ACADL mRNA; beta-hexachlorocyclohexane results in decreased expression of ACADL protein CTD PMID:28397872 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of ACADM mRNA; beta-hexachlorocyclohexane results in decreased expression of ACADM protein CTD PMID:28397872 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acads acyl-CoA dehydrogenase short chain decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of ACADS mRNA; beta-hexachlorocyclohexane results in decreased expression of ACADS protein CTD PMID:28397872 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747
JBrowse link
G Acox1 acyl-CoA oxidase 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of ACOX1 mRNA CTD PMID:28397872 NCBI chr10:104,724,534...104,748,003
Ensembl chr10:104,722,958...104,748,050
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing affects response to substance
multiple interactions
ISO ADIPOQ gene SNP affects the susceptibility to beta-hexachlorocyclohexane
[ADIPOQ gene SNP affects the susceptibility to beta-hexachlorocyclohexane] which affects the expression of ADIPOQ protein
CTD PMID:27883041 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Agtr1a angiotensin II receptor, type 1a decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of AGTR1A mRNA CTD PMID:25270620 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Akap13 A-kinase anchoring protein 13 increases expression ISO beta-hexachlorocyclohexane results in increased expression of AKAP13 mRNA CTD PMID:25270620 NCBI chr 1:137,089,558...137,315,272
Ensembl chr 1:137,014,272...137,315,272
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of ALAS1 mRNA CTD PMID:25270620 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alg5 ALG5, dolichyl-phosphate beta-glucosyltransferase increases expression ISO beta-hexachlorocyclohexane results in increased expression of ALG5 mRNA CTD PMID:25270620 NCBI chr 2:143,932,242...143,946,472
Ensembl chr 2:143,932,739...143,946,466
JBrowse link
G Ank1 ankyrin 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of ANK1 mRNA CTD PMID:25270620 NCBI chr16:73,681,422...73,912,605
Ensembl chr16:73,681,422...73,827,488
JBrowse link
G Apoa5 apolipoprotein A5 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of APOA5 mRNA CTD PMID:25270620 NCBI chr 8:50,559,079...50,561,720
Ensembl chr 8:50,559,126...50,561,736
JBrowse link
G Ar androgen receptor multiple interactions ISO beta-hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:26022396 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp11b ATPase phospholipid transporting 11B (putative) increases expression ISO beta-hexachlorocyclohexane results in increased expression of ATP11B mRNA CTD PMID:25270620 NCBI chr 2:122,337,757...122,445,090
Ensembl chr 2:122,368,265...122,444,878
JBrowse link
G Atp7b ATPase copper transporting beta increases expression ISO beta-hexachlorocyclohexane results in increased expression of ATP7B mRNA CTD PMID:25270620 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of BCR mRNA CTD PMID:25270620 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of BRCA1 mRNA]; fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of BRCA1 mRNA] CTD PMID:20206645 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Casp3 caspase 3 increases cleavage EXP beta-hexachlorocyclohexane results in increased cleavage of CASP3 protein CTD PMID:19760616 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases cleavage EXP beta-hexachlorocyclohexane results in increased cleavage of CASP8 protein CTD PMID:19760616 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Cat catalase multiple interactions EXP [Hexachlorocyclohexane co-treated with alpha-hexachlorocyclohexane co-treated with beta-hexachlorocyclohexane co-treated with delta-hexachlorocyclohexane] results in increased activity of CAT protein CTD PMID:16046044 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccdc63 coiled-coil domain containing 63 increases expression ISO beta-hexachlorocyclohexane results in increased expression of CCDC63 mRNA CTD PMID:25270620 NCBI chr12:39,905,120...39,950,719
Ensembl chr12:39,913,628...39,950,641
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
ISO beta-hexachlorocyclohexane results in increased expression of CCND1 mRNA
fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of CCND1 mRNA]
CTD PMID:17640349 PMID:20206645 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd19 CD19 molecule increases expression ISO beta-hexachlorocyclohexane results in increased expression of CD19 mRNA CTD PMID:25270620 NCBI chr 1:197,815,422...197,822,123
Ensembl chr 1:197,815,413...197,821,936
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO beta-hexachlorocyclohexane results in increased expression of CDKN1B mRNA CTD PMID:17640349 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cers6 ceramide synthase 6 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of CERS6 mRNA CTD PMID:25270620 NCBI chr 3:55,094,240...55,338,370
Ensembl chr 3:55,094,637...55,338,445
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO beta-hexachlorocyclohexane results in increased expression of CES1D mRNA CTD PMID:25270620 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cops8 COP9 signalosome subunit 8 increases expression ISO beta-hexachlorocyclohexane results in increased expression of COPS8 mRNA CTD PMID:25270620 NCBI chr 9:97,772,224...97,782,055
Ensembl chr 9:97,772,184...97,782,067
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of CPT1A mRNA CTD PMID:25270620 PMID:28397872 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Ctss cathepsin S increases expression ISO beta-hexachlorocyclohexane results in increased expression of CTSS mRNA CTD PMID:25270620 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of CYP27A1 mRNA CTD PMID:28392238 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of CYP2B10 mRNA CTD PMID:25270620 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases expression ISO beta-hexachlorocyclohexane results in increased expression of CYP2C55 mRNA CTD PMID:25270620 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of CYP2C38 mRNA CTD PMID:25270620 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases expression ISO beta-hexachlorocyclohexane results in increased expression of CYP2C29 mRNA CTD PMID:25270620 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of CYP7A1 mRNA CTD PMID:28392238 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of CYP8B1 mRNA CTD PMID:28392238 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Dab1 DAB adaptor protein 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of DAB1 mRNA CTD PMID:25270620 NCBI chr 5:123,154,360...124,279,170
Ensembl chr 5:123,905,166...124,280,115
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of DRD2 mRNA CTD PMID:25270620 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of DTL mRNA CTD PMID:25270620 NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
JBrowse link
G Dync2i1 dynein 2 intermediate chain 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of DYNC2I1 mRNA CTD PMID:25270620 NCBI chr 6:144,069,077...144,124,975
Ensembl chr 6:144,069,022...144,123,729
JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma increases expression ISO beta-hexachlorocyclohexane results in increased expression of EIF2B3 mRNA CTD PMID:25270620 NCBI chr 5:135,882,946...135,949,276
Ensembl chr 5:135,882,967...135,949,818
JBrowse link
G Emp2 epithelial membrane protein 2 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of EMP2 mRNA CTD PMID:25270620 NCBI chr10:5,433,248...5,467,840
Ensembl chr10:5,433,248...5,467,839
JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of EPB41 mRNA CTD PMID:25270620 NCBI chr 5:150,081,727...150,243,186
Ensembl chr 5:150,084,611...150,167,077
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases expression
multiple interactions
increases activity
ISO beta-hexachlorocyclohexane results in increased expression of ERBB2 mRNA
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [beta-hexachlorocyclohexane promotes the reaction [ERBB2 protein binds to ERBB3 protein]]; afimoxifene inhibits the reaction [beta-hexachlorocyclohexane promotes the reaction [ERBB2 protein binds to ERBB3 protein]]; beta-hexachlorocyclohexane promotes the reaction [ERBB2 protein binds to ERBB3 protein]
beta-hexachlorocyclohexane results in increased activity of ERBB2 protein
beta-hexachlorocyclohexane results in increased expression of ERBB2 protein
CTD PMID:9443065 PMID:11222871 PMID:12439862 PMID:12948864 PMID:17640349 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [beta-hexachlorocyclohexane promotes the reaction [ERBB2 protein binds to ERBB3 protein]]; afimoxifene inhibits the reaction [beta-hexachlorocyclohexane promotes the reaction [ERBB2 protein binds to ERBB3 protein]]; beta-hexachlorocyclohexane promotes the reaction [ERBB2 protein binds to ERBB3 protein] CTD PMID:12439862 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of ERMP1 mRNA CTD PMID:25270620 NCBI chr 1:247,784,830...247,821,771
Ensembl chr 1:247,787,582...247,821,728
JBrowse link
G Esr1 estrogen receptor 1 decreases expression
increases expression
multiple interactions
increases activity
ISO beta-hexachlorocyclohexane results in decreased expression of ESR1 mRNA; beta-hexachlorocyclohexane results in decreased expression of ESR1 protein
beta-hexachlorocyclohexane results in increased expression of ESR1 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beta-hexachlorocyclohexane results in decreased expression of ESR1 mRNA]; fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in decreased expression of ESR1 mRNA]
beta-hexachlorocyclohexane results in increased expression of ESR1 protein
beta-hexachlorocyclohexane results in increased activity of ESR1 protein
[Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in increased expression of ESR1 mRNA; beta-hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR1 protein]
CTD PMID:12948864 PMID:15064155 PMID:15541753 PMID:16758953 PMID:20206645 PMID:21278053 PMID:21295777 PMID:26022396 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases activity
ISO beta-hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR2 protein]
beta-hexachlorocyclohexane results in increased activity of ESR2 protein
CTD PMID:15064155 PMID:21278053 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Etv1 ETS variant transcription factor 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of ETV1 mRNA CTD PMID:25270620 NCBI chr 6:58,467,215...58,558,640
Ensembl chr 6:58,467,254...58,558,631
JBrowse link
G Exosc8 exosome component 8 increases expression ISO beta-hexachlorocyclohexane results in increased expression of EXOSC8 mRNA CTD PMID:25270620 NCBI chr 2:143,925,643...143,932,240
Ensembl chr 2:143,925,546...143,931,940
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO beta-hexachlorocyclohexane results in increased expression of FABP5 mRNA CTD PMID:28392238 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fam107a family with sequence similarity 107, member A decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of FAM107A mRNA CTD PMID:25270620 NCBI chr15:18,399,145...18,415,959
Ensembl chr15:18,399,515...18,415,965
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of FASLG protein] CTD PMID:19760616 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase increases expression ISO beta-hexachlorocyclohexane results in increased expression of FASN protein CTD PMID:27203212 PMID:28397872 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fgf19 fibroblast growth factor 19 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of FGF15 mRNA CTD PMID:28392238 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity EXP beta-hexachlorocyclohexane results in increased activity of G6PD protein CTD PMID:2461408 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO [Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in increased expression of GNRH1 mRNA CTD PMID:16758953 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Gpr146 G protein-coupled receptor 146 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of GPR146 mRNA CTD PMID:25270620 NCBI chr12:17,343,396...17,358,631
Ensembl chr12:17,345,510...17,358,617
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP [Hexachlorocyclohexane co-treated with alpha-hexachlorocyclohexane co-treated with beta-hexachlorocyclohexane co-treated with delta-hexachlorocyclohexane] results in increased activity of GSR protein CTD PMID:16046044 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 gene polymorphism affects the susceptibility to beta-hexachlorocyclohexane CTD PMID:22310945 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of HMOX1 mRNA CTD PMID:25270620 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hyal1 hyaluronidase 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of HYAL1 mRNA CTD PMID:25270620 NCBI chr 8:116,332,834...116,337,522
Ensembl chr 8:116,332,796...116,335,435
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO beta-hexachlorocyclohexane results in increased expression of IGF1R mRNA CTD PMID:17640349 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igsf3 immunoglobulin superfamily, member 3 increases expression ISO beta-hexachlorocyclohexane results in increased expression of IGSF3 mRNA CTD PMID:25270620 NCBI chr 2:203,768,364...203,855,573
Ensembl chr 2:203,768,117...203,855,573
JBrowse link
G Jmjd6 jumonji domain containing 6, arginine demethylase and lysine hydroxylase increases expression ISO beta-hexachlorocyclohexane results in increased expression of JMJD6 mRNA CTD PMID:25270620 NCBI chr10:105,781,752...105,787,803
Ensembl chr10:105,781,753...105,787,803
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP [beta-hexachlorocyclohexane co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of JUN mRNA
beta-hexachlorocyclohexane results in increased expression of JUN mRNA
CTD PMID:18481421 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kank3 KN motif and ankyrin repeat domains 3 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of KANK3 mRNA CTD PMID:25270620 NCBI chr 7:18,668,665...18,681,945
Ensembl chr 7:18,668,692...18,681,939
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of KCND2 mRNA CTD PMID:25270620 NCBI chr 4:48,309,283...48,816,804 JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 increases expression ISO beta-hexachlorocyclohexane results in increased expression of KDELR2 mRNA CTD PMID:25270620 NCBI chr12:13,192,452...13,210,758
Ensembl chr12:13,192,453...13,210,758
JBrowse link
G Kif24 kinesin family member 24 increases expression ISO beta-hexachlorocyclohexane results in increased expression of KIF24 mRNA CTD PMID:25270620 NCBI chr 5:57,778,730...57,845,642
Ensembl chr 5:57,780,389...57,845,509
JBrowse link
G Krt19 keratin 19 increases expression ISO beta-hexachlorocyclohexane results in increased expression of KRT19 mRNA CTD PMID:17640349 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Lcn8 lipocalin 8 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of LCN8 mRNA CTD PMID:25270620 NCBI chr 3:2,871,890...2,875,682
Ensembl chr 3:2,872,031...2,875,015
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases expression
multiple interactions
ISO beta-hexachlorocyclohexane results in decreased expression of MAPK1 protein
beta-hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD PMID:12948864 PMID:20206645 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression
multiple interactions
ISO beta-hexachlorocyclohexane results in decreased expression of MAPK3 protein
beta-hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD PMID:12948864 PMID:20206645 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
EXP beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein
Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein]
CTD PMID:19760616 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation
EXP Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK9 protein] CTD PMID:19760616 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of MGME1 mRNA CTD PMID:25270620 NCBI chr 3:138,397,925...138,406,672
Ensembl chr 3:138,398,011...138,406,666
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO beta-hexachlorocyclohexane results in increased expression of MMP12 mRNA CTD PMID:17640349 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression ISO beta-hexachlorocyclohexane results in increased expression of MMP13 mRNA CTD PMID:17640349 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression ISO beta-hexachlorocyclohexane results in increased expression of MMP9 protein CTD PMID:12948864 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mroh9 maestro heat-like repeat family member 9 increases expression ISO beta-hexachlorocyclohexane results in increased expression of MROH9 mRNA CTD PMID:25270620 NCBI chr13:80,928,982...80,986,373
Ensembl chr13:80,928,995...80,968,971
JBrowse link
G Mylip myosin regulatory light chain interacting protein decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of MYLIP mRNA CTD PMID:25270620 NCBI chr17:19,682,040...19,703,681
Ensembl chr17:19,682,040...19,703,681
JBrowse link
G Myo1e myosin IE decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of MYO1E mRNA CTD PMID:25270620 NCBI chr 8:76,644,715...76,840,240
Ensembl chr 8:76,754,492...76,839,593
JBrowse link
G Nadk NAD kinase increases expression ISO beta-hexachlorocyclohexane results in increased expression of NADK mRNA CTD PMID:25270620 NCBI chr 5:172,984,930...173,015,505
Ensembl chr 5:172,986,291...173,015,494
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression ISO beta-hexachlorocyclohexane results in increased expression of NR1H4 mRNA CTD PMID:28392238 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO beta-hexachlorocyclohexane binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr2c1 nuclear receptor subfamily 2, group C, member 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of NR2C1 mRNA CTD PMID:25270620 NCBI chr 7:35,069,807...35,122,810
Ensembl chr 7:35,069,814...35,122,796
JBrowse link
G Ntsr2 neurotensin receptor 2 increases expression ISO beta-hexachlorocyclohexane results in increased expression of NTSR2 mRNA CTD PMID:25270620 NCBI chr 6:41,917,065...41,923,780
Ensembl chr 6:41,917,132...41,923,542
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of PDGFRB mRNA CTD PMID:25270620 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of PFKFB1 mRNA CTD PMID:25270620 NCBI chr  X:23,092,143...23,145,923
Ensembl chr  X:23,092,159...23,144,324
JBrowse link
G Pgr progesterone receptor multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of PGR mRNA]; beta-hexachlorocyclohexane inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]; fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of PGR mRNA]; ICI 164384 inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of PGR mRNA]
beta-hexachlorocyclohexane results in increased expression of PGR; beta-hexachlorocyclohexane results in increased expression of PGR mRNA
CTD PMID:2479123 PMID:16242299 PMID:20206645 PMID:26022396 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression ISO beta-hexachlorocyclohexane results in increased expression of PLA2G12A mRNA CTD PMID:25270620 NCBI chr 2:235,311,664...235,327,972
Ensembl chr 2:235,311,719...235,327,972
JBrowse link
G Pla2g15 phospholipase A2, group XV decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of PLA2G15 mRNA CTD PMID:25270620 NCBI chr19:38,129,666...38,146,958
Ensembl chr19:38,129,584...38,146,956
JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of POLR1B mRNA CTD PMID:25270620 NCBI chr 3:121,632,043...121,656,506
Ensembl chr 3:121,632,043...121,656,506
JBrowse link
G Pomc proopiomelanocortin multiple interactions ISO [Dichlorodiphenyl Dichloroethylene co-treated with beta-hexachlorocyclohexane] results in decreased expression of POMC mRNA CTD PMID:16758953 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO beta-hexachlorocyclohexane results in increased expression of POR mRNA CTD PMID:25270620 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Prl prolactin multiple interactions
increases expression
ISO ICI 164384 inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of PRL mRNA] CTD PMID:8968093 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prpf18 pre-mRNA processing factor 18 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of PRPF18 mRNA CTD PMID:25270620 NCBI chr17:77,601,914...77,632,507
Ensembl chr17:77,601,877...77,663,980
JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 increases expression ISO beta-hexachlorocyclohexane results in increased expression of PSMD12 mRNA CTD PMID:25270620 NCBI chr10:95,706,808...95,725,452
Ensembl chr10:95,706,685...95,725,812
JBrowse link
G Ptges prostaglandin E synthase increases expression ISO beta-hexachlorocyclohexane results in increased expression of PTGES mRNA CTD PMID:25270620 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
affects localization
EXP Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane affects the localization of RELA protein] CTD PMID:19760616 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rgs3 regulator of G-protein signaling 3 increases expression ISO beta-hexachlorocyclohexane results in increased expression of RGS3 mRNA CTD PMID:25270620 NCBI chr 5:78,429,017...78,567,281
Ensembl chr 5:78,428,669...78,567,288
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO beta-hexachlorocyclohexane results in increased expression of SCD1 mRNA; beta-hexachlorocyclohexane results in increased expression of SCD1 protein CTD PMID:27203212 PMID:28397872 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Serpina7 serpin family A member 7 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of SERPINA7 protein CTD PMID:19750101 NCBI chr  X:110,226,565...110,232,202
Ensembl chr  X:110,226,572...110,232,179
JBrowse link
G Sh3d21 SH3 domain containing 21 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of SH3D21 mRNA CTD PMID:25270620 NCBI chr 5:144,161,881...144,178,161
Ensembl chr 5:144,162,141...144,176,807
JBrowse link
G Slc10a1 solute carrier family 10 member 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of SLC10A1 mRNA CTD PMID:28392238 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc10a2 solute carrier family 10 member 2 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of SLC10A2 mRNA CTD PMID:28392238 NCBI chr16:90,324,420...90,350,254
Ensembl chr16:90,324,361...90,345,865
JBrowse link
G Slc27a1 solute carrier family 27 member 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of SLC27A1 mRNA CTD PMID:25270620 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases expression ISO beta-hexachlorocyclohexane results in increased expression of SLC29A1 mRNA CTD PMID:25270620 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression EXP beta-hexachlorocyclohexane results in decreased expression of SLC2A4 protein CTD PMID:31923579 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc51a solute carrier family 51 subunit alpha decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of SLC51A mRNA CTD PMID:28392238 NCBI chr11:71,533,078...71,547,476
Ensembl chr11:71,533,078...71,547,476
JBrowse link
G Slc51b solute carrier family 51 subunit beta decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of SLC51B mRNA CTD PMID:28392238 NCBI chr 8:70,930,196...70,938,559
Ensembl chr 8:70,930,347...70,932,986
JBrowse link
G Sntb2 syntrophin, beta 2 increases expression ISO beta-hexachlorocyclohexane results in increased expression of SNTB2 mRNA CTD PMID:25270620 NCBI chr19:39,126,589...39,209,152
Ensembl chr19:39,126,589...39,209,152
JBrowse link
G Spag16 sperm associated antigen 16 increases expression ISO beta-hexachlorocyclohexane results in increased expression of SPAG16 mRNA CTD PMID:25270620 NCBI chr 9:77,027,626...77,833,476
Ensembl chr 9:77,320,726...77,833,281
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO beta-hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of SRC protein CTD PMID:20206645 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srcap Snf2-related CREBBP activator protein increases expression ISO beta-hexachlorocyclohexane results in increased expression of SRCAP mRNA CTD PMID:25270620 NCBI chr 1:198,957,764...199,007,576
Ensembl chr 1:198,960,542...199,007,347
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
increases expression
ISO beta-hexachlorocyclohexane results in decreased expression of SREBF1 mRNA
beta-hexachlorocyclohexane results in increased expression of SREBF1 mRNA; beta-hexachlorocyclohexane results in increased expression of SREBF1 protein
CTD PMID:25270620 PMID:27203212 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tacc1 transforming, acidic coiled-coil containing protein 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of TACC1 mRNA CTD PMID:25270620 NCBI chr16:71,596,970...71,681,126
Ensembl chr16:71,629,525...71,681,126
JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of TFF1 mRNA]; ICI 164384 inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of TFF1 mRNA] CTD PMID:8968093 PMID:16242299 PMID:20206645 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Thumpd2 THUMP domain containing 2 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of THUMPD2 mRNA CTD PMID:25270620 NCBI chr 6:3,743,080...3,794,512
Ensembl chr 6:3,743,074...3,794,501
JBrowse link
G Tns1 tensin 1 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of TNS1 mRNA CTD PMID:25270620 NCBI chr 9:81,190,192...81,401,020
Ensembl chr 9:81,194,119...81,400,987
JBrowse link
G Tpm3 tropomyosin 3 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of TPM3 mRNA CTD PMID:25270620 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Trim42 tripartite motif-containing 42 increases expression ISO beta-hexachlorocyclohexane results in increased expression of TRIM42 mRNA CTD PMID:25270620 NCBI chr 8:105,205,041...105,226,541
Ensembl chr 8:105,204,993...105,226,588
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO beta-hexachlorocyclohexane affects the expression of and affects the secretion of TSHB protein CTD PMID:19750101 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Tssc4 tumor suppressing subtransferable candidate 4 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of TSSC4 mRNA CTD PMID:25270620 NCBI chr 1:216,253,786...216,256,610
Ensembl chr 1:216,254,979...216,256,608
JBrowse link
G Ttc39b tetratricopeptide repeat domain 39B increases expression ISO beta-hexachlorocyclohexane results in increased expression of TTC39B mRNA CTD PMID:25270620 NCBI chr 5:101,304,982...101,405,689
Ensembl chr 5:101,304,982...101,405,656
JBrowse link
G Zfp113 zinc finger protein 3 increases expression ISO beta-hexachlorocyclohexane results in increased expression of ZFP113 mRNA CTD PMID:25270620 NCBI chr12:19,287,541...19,298,172
Ensembl chr12:19,288,403...19,294,888
JBrowse link
G Zfp597 zinc finger protein 597 decreases expression ISO beta-hexachlorocyclohexane results in decreased expression of ZFP597 mRNA CTD PMID:25270620 NCBI chr10:11,912,245...11,917,919
Ensembl chr10:11,912,543...11,917,898
JBrowse link
delta-hexachlorocyclohexane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO delta-hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; delta-hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:10696776 PMID:26022396 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Casp3 caspase 3 increases activity ISO delta-hexachlorocyclohexane results in increased activity of CASP3 protein CTD PMID:19818741 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP [Hexachlorocyclohexane co-treated with alpha-hexachlorocyclohexane co-treated with beta-hexachlorocyclohexane co-treated with delta-hexachlorocyclohexane] results in increased activity of CAT protein CTD PMID:16046044 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase decreases activity
multiple interactions
ISO delta-hexachlorocyclohexane results in decreased activity of CDIPT protein
[delta-hexachlorocyclohexane results in decreased activity of CDIPT protein] which results in decreased abundance of Cytidine Monophosphate; delta-hexachlorocyclohexane inhibits the reaction [CDIPT protein results in increased chemical synthesis of Cytidine Diphosphate Diglycerides]
CTD PMID:2579070 NCBI chr 1:198,409,186...198,413,497
Ensembl chr 1:198,409,360...198,413,497
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO delta-hexachlorocyclohexane results in increased activity of ESR1 protein CTD PMID:15064155 PMID:26022396 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO delta-hexachlorocyclohexane results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
EXP delta-hexachlorocyclohexane inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of FOS mRNA]; delta-hexachlorocyclohexane inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of FOS protein]; delta-hexachlorocyclohexane inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS mRNA]; delta-hexachlorocyclohexane inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS protein]; delta-hexachlorocyclohexane inhibits the reaction [Pentylenetetrazole results in increased expression of FOS mRNA]; delta-hexachlorocyclohexane inhibits the reaction [Pentylenetetrazole results in increased expression of FOS protein]
delta-hexachlorocyclohexane results in decreased expression of FOS mRNA; delta-hexachlorocyclohexane results in decreased expression of FOS protein
CTD PMID:1380685 PMID:7534335 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; delta-hexachlorocyclohexane results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] CTD PMID:9316872 PMID:11156579 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 multiple interactions ISO delta-hexachlorocyclohexane results in decreased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRG2 protein alternative form] CTD PMID:11156579 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 multiple interactions ISO delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein] CTD PMID:9316872 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions ISO delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form] CTD PMID:11156579 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; delta-hexachlorocyclohexane results in decreased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRG2 protein alternative form] CTD PMID:11156579 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 multiple interactions ISO [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]; delta-hexachlorocyclohexane results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] CTD PMID:9316872 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO [delta-hexachlorocyclohexane co-treated with Lanthanum] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; [delta-hexachlorocyclohexane co-treated with loreclezole] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; delta-hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]; delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; delta-hexachlorocyclohexane results in decreased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]; delta-hexachlorocyclohexane results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]; delta-hexachlorocyclohexane results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]] CTD PMID:9316872 PMID:11156579 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP [Hexachlorocyclohexane co-treated with alpha-hexachlorocyclohexane co-treated with beta-hexachlorocyclohexane co-treated with delta-hexachlorocyclohexane] results in increased activity of GSR protein CTD PMID:16046044 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO delta-hexachlorocyclohexane results in decreased expression of HSD3B1 mRNA CTD PMID:10993823
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO delta-hexachlorocyclohexane binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Pgr progesterone receptor multiple interactions ISO delta-hexachlorocyclohexane inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein] CTD PMID:26022396 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Shbg sex hormone binding globulin multiple interactions ISO
EXP
delta-hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone binds to SHBG protein] CTD PMID:9171990 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO delta-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; delta-hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein] CTD PMID:10993823 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
gamma-hexachlorocyclohexane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO Hexachlorocyclohexane results in increased expression of ABCA1 mRNA CTD PMID:24356939 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Hexachlorocyclohexane results in increased expression of ABCB1 mRNA CTD PMID:24464585 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Hexachlorocyclohexane results in increased expression of ABCC3 mRNA CTD PMID:17785943 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Hexachlorocyclohexane results in increased expression of ABCG1 mRNA CTD PMID:24356939 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Hexachlorocyclohexane results in increased expression of ABCG2 mRNA CTD PMID:24464585 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
increases activity
affects activity
ISO
EXP
Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein]
Hexachlorocyclohexane results in decreased activity of ACHE protein
Hexachlorocyclohexane results in increased activity of ACHE protein
Hexachlorocyclohexane affects the activity of ACHE protein
CTD PMID:6186625 PMID:19893075 PMID:20663516 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acly ATP citrate lyase decreases expression
affects activity
EXP Hexachlorocyclohexane results in decreased expression of ACLY mRNA
Hexachlorocyclohexane affects the activity of ACLY protein
CTD PMID:7535533 PMID:17785943 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G Aco2 aconitase 2 increases expression EXP Hexachlorocyclohexane results in increased expression of ACO2 mRNA CTD PMID:17785943 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression EXP Hexachlorocyclohexane results in decreased expression of ACSL5 mRNA CTD PMID:17785943 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Actb actin, beta affects expression EXP Hexachlorocyclohexane affects the expression of ACTB mRNA CTD PMID:22001173 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Acvr1 activin A receptor type 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of ACVR1 mRNA CTD PMID:17785943 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Acvr1c activin A receptor type 1C increases expression EXP Hexachlorocyclohexane results in increased expression of ACVR1C mRNA CTD PMID:17785943 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
JBrowse link
G Add3 adducin 3 affects expression EXP Hexachlorocyclohexane affects the expression of ADD3 mRNA CTD PMID:17785943 NCBI chr 1:273,854,195...273,961,982
Ensembl chr 1:273,854,248...273,961,982
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression EXP Hexachlorocyclohexane results in increased expression of AHR mRNA CTD PMID:17785943 PMID:25572523 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO Hexachlorocyclohexane results in decreased expression of AK4 mRNA CTD PMID:24356939 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Hexachlorocyclohexane results in increased expression of AKR7A3 mRNA CTD PMID:17785943 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation EXP Hexachlorocyclohexane results in decreased phosphorylation of AKT1 protein CTD PMID:30248393 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 increases expression ISO Hexachlorocyclohexane results in increased expression of ALDH8A1 mRNA CTD PMID:24356939 NCBI chr 1:16,910,043...16,929,465
Ensembl chr 1:16,910,069...16,930,481
JBrowse link
G Alk ALK receptor tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of ALK mRNA CTD PMID:28263720 NCBI chr 6:22,696,415...23,203,791
Ensembl chr 6:22,696,397...23,203,775
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
increases expression
increases activity
EXP [Hexachlorocyclohexane co-treated with isoproturon] results in decreased activity of ALPL protein; [Hexachlorocyclohexane co-treated with isoproturon] results in increased expression of ALPL protein
Hexachlorocyclohexane results in increased expression of ALPL protein
Hexachlorocyclohexane results in increased activity of ALPL protein
CTD PMID:11180283 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Apob apolipoprotein B affects expression EXP Hexachlorocyclohexane affects the expression of APOB mRNA CTD PMID:17785943 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Ar androgen receptor affects binding
multiple interactions
EXP
ISO
Hexachlorocyclohexane binds to AR protein
[DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Hydrocarbons, Chlorinated] inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
CTD PMID:14565775 PMID:21295777 PMID:26022396 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Armc6 armadillo repeat containing 6 decreases expression EXP Hexachlorocyclohexane results in decreased expression of ARMC6 mRNA CTD PMID:17785943 NCBI chr16:20,939,311...20,949,732
Ensembl chr16:20,939,655...20,954,246
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator increases expression EXP Hexachlorocyclohexane results in increased expression of ARNT mRNA CTD PMID:25572523 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Arsa arylsulfatase A decreases activity ISO Hexachlorocyclohexane results in decreased activity of ARSA protein CTD PMID:16818664 NCBI chr 7:130,446,644...130,452,632
Ensembl chr 7:130,446,668...130,451,283
JBrowse link
G Asip agouti signaling protein increases response to substance ISO A mutant form results in increased susceptibility to Hexachlorocyclohexane CTD PMID:2445499 NCBI chr 3:150,492,010...150,579,870
Ensembl chr 3:150,574,473...150,579,870
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Hexachlorocyclohexane results in increased expression of ASNS mRNA CTD PMID:24356939 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta decreases expression EXP Hexachlorocyclohexane results in decreased expression of ATP5F1D mRNA CTD PMID:17785943 NCBI chr 7:12,426,807...12,432,120
Ensembl chr 7:12,426,809...12,432,130
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of ATPIF1 mRNA CTD PMID:17785943 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
decreases expression
multiple interactions
ISO
EXP
Hexachlorocyclohexane results in increased expression of BAX mRNA; Hexachlorocyclohexane results in increased expression of BAX protein
Hexachlorocyclohexane results in decreased expression of BAX protein
Estradiol inhibits the reaction [Hexachlorocyclohexane results in decreased expression of BAX protein]; Hexachlorocyclohexane inhibits the reaction [Estradiol results in decreased expression of BAX protein]; Hexachlorocyclohexane promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of BAX protein]
CTD PMID:14688026 PMID:18174961 PMID:19041923 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases activity
ISO Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein]
Hexachlorocyclohexane results in decreased activity of BCHE protein
CTD PMID:20455324 PMID:20663516 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
increases expression
multiple interactions
ISO
EXP
Hexachlorocyclohexane results in decreased expression of BCL2 protein
Hexachlorocyclohexane results in increased expression of BCL2 mRNA; Hexachlorocyclohexane results in increased expression of BCL2 protein
[Hexachlorocyclohexane co-treated with Estradiol] results in increased expression of BCL2 protein
Hexachlorocyclohexane promotes the reaction [BECN1 protein binds to BCL2 protein]
CTD PMID:14688026 PMID:18174961 PMID:19041923 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
multiple interactions
EXP Hexachlorocyclohexane results in increased expression of BCL2L1 protein
Ro 31-8220 inhibits the reaction [Hexachlorocyclohexane results in increased expression of BCL2L1 protein]; TEMPO inhibits the reaction [Hexachlorocyclohexane results in increased expression of BCL2L1 protein]
CTD PMID:19041923 PMID:22001173 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl6 BCL6, transcription repressor increases expression ISO Hexachlorocyclohexane results in increased expression of BCL6 mRNA CTD PMID:24356939 NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Hexachlorocyclohexane results in increased expression of BDNF protein CTD PMID:11279263 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 affects expression
multiple interactions
EXP Hexachlorocyclohexane affects the expression of BECN1 protein
Hexachlorocyclohexane promotes the reaction [BECN1 protein binds to BCL2 protein]
CTD PMID:19041923 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bhlha15 basic helix-loop-helix family, member a15 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of BHLHA15 mRNA CTD PMID:28263720 NCBI chr12:12,403,385...12,409,103
Ensembl chr12:12,403,385...12,407,561
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression EXP Hexachlorocyclohexane results in decreased expression of BHLHE40 mRNA CTD PMID:17785943 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO Hexachlorocyclohexane results in increased expression of BIRC3 mRNA CTD PMID:24356939 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Calr calreticulin decreases expression EXP Hexachlorocyclohexane results in decreased expression of CALR mRNA CTD PMID:17785943 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO Hexachlorocyclohexane results in increased expression of CARS1 mRNA CTD PMID:24356939 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp3 caspase 3 increases expression
increases activity
multiple interactions
decreases activity
EXP
ISO
Hexachlorocyclohexane results in increased expression of CASP3 mRNA; Hexachlorocyclohexane results in increased expression of CASP3 protein
Hexachlorocyclohexane results in increased activity of CASP3 protein
[Hexachlorocyclohexane co-treated with Dieldrin] results in increased activity of CASP3 protein; Ro 31-8220 inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP3 protein]; TEMPO inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP3 protein]
Hexachlorocyclohexane results in decreased activity of CASP3 protein
CTD PMID:19038305 PMID:19041923 PMID:19221147 PMID:19815060 PMID:20036686 PMID:22001173 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions EXP [Hexachlorocyclohexane co-treated with Dieldrin] results in increased activity of CASP7 protein CTD PMID:20036686 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
increases activity
decreases activity
EXP Hexachlorocyclohexane results in increased expression of CASP9 protein
Ro 31-8220 inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP9 protein]; TEMPO inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP9 protein]
Hexachlorocyclohexane results in decreased activity of CASP9 protein
CTD PMID:19038305 PMID:19041923 PMID:22001173 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin increases expression EXP Hexachlorocyclohexane results in increased expression of CAST mRNA CTD PMID:17785943 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase multiple interactions
increases activity
decreases activity
ISO
EXP
Plant Extracts inhibits the reaction [Hexachlorocyclohexane results in decreased activity of CAT protein]
Hexachlorocyclohexane results in increased activity of CAT protein
[Hexachlorocyclohexane co-treated with alpha-hexachlorocyclohexane co-treated with beta-hexachlorocyclohexane co-treated with delta-hexachlorocyclohexane] results in increased activity of CAT protein; [Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of CAT protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of CAT protein; [Phenobarbital co-treated with Hexachlorocyclohexane] results in decreased activity of CAT protein; [Triiodothyronine co-treated with Hexachlorocyclohexane] results in decreased activity of CAT protein; Curcumin inhibits the reaction [Hexachlorocyclohexane results in decreased activity of CAT protein]; gadolinium chloride inhibits the reaction [[Triiodothyronine co-treated with Hexachlorocyclohexane] results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Hexachlorocyclohexane results in decreased activity of CAT protein]
CTD PMID:1708174 PMID:2429406 PMID:2469257 PMID:9057899 PMID:9467884 PMID:9704597 PMID:10097797 PMID:10817630 PMID:11349524 PMID:11404799 PMID:11561191 PMID:12364975 PMID:12516873 PMID:16046044 PMID:16127354 PMID:16432761 PMID:17884035 PMID:17997001 PMID:20182699 PMID:20455324 PMID:21976817 PMID:22224058 PMID:22302394 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccng2 cyclin G2 increases expression ISO Hexachlorocyclohexane results in increased expression of CCNG2 mRNA CTD PMID:24356939 NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
JBrowse link
G Cd47 Cd47 molecule decreases expression EXP Hexachlorocyclohexane results in decreased expression of CD47 mRNA CTD PMID:17785943 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd69 Cd69 molecule increases expression ISO Hexachlorocyclohexane results in increased expression of CD69 mRNA CTD PMID:24356939 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd84 CD84 molecule increases expression ISO Hexachlorocyclohexane results in increased expression of CD84 mRNA CTD PMID:24356939 NCBI chr13:90,241,369...90,283,625
Ensembl chr13:90,244,681...90,277,865
JBrowse link
G Cdc42 cell division cycle 42 decreases expression EXP Hexachlorocyclohexane results in decreased expression of CDC42 mRNA CTD PMID:17785943 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase affects activity ISO Hexachlorocyclohexane affects the activity of CDIPT protein CTD PMID:2579070 NCBI chr 1:198,409,186...198,413,497
Ensembl chr 1:198,409,360...198,413,497
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
multiple interactions
ISO
EXP
Hexachlorocyclohexane results in increased expression of CDKN1A mRNA; Hexachlorocyclohexane results in increased expression of CDKN1A protein
Hexachlorocyclohexane results in decreased expression of CDKN1A protein
Hexachlorocyclohexane affects the reaction [Benzo(a)pyrene results in increased expression of CDKN1A mRNA]; Hexachlorocyclohexane inhibits the reaction [Estradiol results in increased expression of CDKN1A protein]
CTD PMID:14688026 PMID:17785943 PMID:18174961 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Hexachlorocyclohexane results in increased expression of CEBPB mRNA CTD PMID:24356939 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Hexachlorocyclohexane results in increased expression of CES2 mRNA CTD PMID:17785943 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Hexachlorocyclohexane results in increased expression of CHAC1 mRNA CTD PMID:23824090 PMID:24356939 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Cidea cell death-inducing DFFA-like effector a decreases expression EXP Hexachlorocyclohexane results in decreased expression of CIDEA mRNA CTD PMID:17785943 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression EXP Hexachlorocyclohexane results in decreased expression of CISH mRNA CTD PMID:17785943 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression EXP Hexachlorocyclohexane results in increased expression of CITED2 mRNA CTD PMID:17785943 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Clcn5 chloride voltage-gated channel 5 decreases expression EXP Hexachlorocyclohexane results in decreased expression of CLCN5 mRNA CTD PMID:17785943 NCBI chr  X:16,170,585...16,196,691
Ensembl chr  X:16,050,780...16,196,789
JBrowse link
G Clu clusterin increases expression EXP Hexachlorocyclohexane results in increased expression of CLU protein CTD PMID:17997001 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of CNGA1 mRNA CTD PMID:17785943 NCBI chr14:38,155,771...38,171,107
Ensembl chr14:38,155,759...38,171,010
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases activity EXP Hexachlorocyclohexane results in decreased activity of CNP protein CTD PMID:1701514 NCBI chr10:88,490,798...88,497,357
Ensembl chr10:88,490,798...88,497,356
JBrowse link
G Cpd carboxypeptidase D increases expression EXP Hexachlorocyclohexane results in increased expression of CPD mRNA CTD PMID:17785943 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 increases expression ISO Hexachlorocyclohexane results in increased expression of CRIM1 mRNA CTD PMID:24356939 NCBI chr 6:788,490...962,663
Ensembl chr 6:788,548...960,703
JBrowse link
G Cst8 cystatin 8 affects expression EXP Hexachlorocyclohexane affects the expression of CST8 mRNA CTD PMID:17785943 NCBI chr 3:143,129,240...143,141,000
Ensembl chr 3:143,129,248...143,156,177
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression ISO Hexachlorocyclohexane results in decreased expression of CX3CR1 mRNA CTD PMID:24356939 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cycs cytochrome c, somatic affects expression EXP Hexachlorocyclohexane affects the expression of CYCS mRNA CTD PMID:17785943 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO
EXP
Hexachlorocyclohexane results in decreased expression of CYP11A1 mRNA
Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11A1 mRNA]
Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased expression of CYP11A1 protein]
CTD PMID:15749814 PMID:17080404 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions ISO Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11B1 mRNA] CTD PMID:17080404 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 multiple interactions ISO Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP11B2 mRNA] CTD PMID:17080404 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP17A1 mRNA] CTD PMID:17080404 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
decreases activity
ISO Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of CYP19A1 mRNA]
Hexachlorocyclohexane results in increased expression of CYP19A1 mRNA
Hexachlorocyclohexane results in increased activity of CYP19A1 protein
Hexachlorocyclohexane results in decreased activity of CYP19A1 protein
CTD PMID:12849724 PMID:17080404 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
multiple interactions
ISO
EXP
Hexachlorocyclohexane results in increased activity of CYP1A1 protein
Hexachlorocyclohexane results in increased expression of CYP1A1 mRNA; Hexachlorocyclohexane results in increased expression of CYP1A1 protein
Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A1 protein; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A1 protein]; Phenobarbital promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A1 protein]
Hexachlorocyclohexane inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]
CTD PMID:11684361 PMID:12842176 PMID:15620088 PMID:16641539 PMID:17919674 PMID:17984293 PMID:18174961 PMID:18486174 PMID:23927878 PMID:25572523 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
multiple interactions
EXP Hexachlorocyclohexane results in increased activity of CYP1A2 protein
Hexachlorocyclohexane results in increased expression of CYP1A2 mRNA; Hexachlorocyclohexane results in increased expression of CYP1A2 protein
Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein]; Phenobarbital promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP1A2 protein]
CTD PMID:12842176 PMID:16641539 PMID:17919674 PMID:17984293 PMID:18486174 PMID:23927878 PMID:25572523 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of CYP1B1 mRNA CTD PMID:17785943 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases activity EXP Hexachlorocyclohexane results in increased activity of CYP2A1 protein CTD PMID:3569844 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression
multiple interactions
increases activity
EXP Hexachlorocyclohexane results in increased expression of CYP2B1 mRNA; Hexachlorocyclohexane results in increased expression of CYP2B1 protein
Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B1 protein; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B1 protein]; Phenobarbital promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B1 protein]
Hexachlorocyclohexane results in increased activity of CYP2B1 protein
CTD PMID:11684361 PMID:12842176 PMID:17919674 PMID:17984293 PMID:18486174 PMID:23927878 PMID:25572523 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
multiple interactions
increases activity
EXP Hexachlorocyclohexane results in increased expression of CYP2B2 mRNA; Hexachlorocyclohexane results in increased expression of CYP2B2 protein
Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B2 protein; Methylcholanthrene promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B2 protein]; Phenobarbital promotes the reaction [Hexachlorocyclohexane results in increased expression of and results in increased activity of CYP2B2 protein]
Hexachlorocyclohexane results in increased activity of CYP2B2 protein
CTD PMID:11684361 PMID:12842176 PMID:17785943 PMID:17919674 PMID:17984293 PMID:18486174 PMID:23927878 PMID:25572523 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Hexachlorocyclohexane results in increased expression of CYP2B6 mRNA; Hexachlorocyclohexane results in increased expression of CYP2B6 protein CTD PMID:15548381 PMID:20035023 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP Hexachlorocyclohexane results in increased expression of CYP2C11 mRNA; Hexachlorocyclohexane results in increased expression of CYP2C11 protein CTD PMID:11684361 PMID:16837770 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression EXP Hexachlorocyclohexane results in decreased expression of CYP2C12 mRNA CTD PMID:17785943 NCBI chr 1:258,709,726...258,766,873
Ensembl chr 1:258,709,721...258,766,881
JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 increases expression EXP Hexachlorocyclohexane results in increased expression of CYP2D1 mRNA CTD PMID:25572523 NCBI chr 7:123,625,641...123,630,045
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases expression ISO Hexachlorocyclohexane results in decreased expression of CYP2D6 mRNA CTD PMID:20035023 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity
increases expression
decreases response to substance
decreases expression
EXP
ISO
Hexachlorocyclohexane results in increased activity of CYP2E1 protein
Hexachlorocyclohexane results in increased expression of CYP2E1 mRNA; Hexachlorocyclohexane results in increased expression of CYP2E1 protein
CYP2E1 protein results in decreased susceptibility to Hexachlorocyclohexane
Hexachlorocyclohexane results in decreased expression of CYP2E1 mRNA
CTD PMID:12842176 PMID:14631868 PMID:17919674 PMID:17984293 PMID:20035023 PMID:21458603 PMID:23927878 PMID:25572523 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
increases activity
EXP Hexachlorocyclohexane results in increased expression of CYP3A2 mRNA; Hexachlorocyclohexane results in increased expression of CYP3A2 protein
Hexachlorocyclohexane results in increased activity of CYP3A2 protein
CTD PMID:3569844 PMID:11684361 PMID:16837770 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression
affects expression
EXP Hexachlorocyclohexane results in increased expression of CYP3A23-3A1 mRNA
Hexachlorocyclohexane affects the expression of CYP3A23-3A1 mRNA
CTD PMID:14613717 PMID:22001173 PMID:25572523 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression ISO Hexachlorocyclohexane results in increased expression of CYP3A4 protein CTD PMID:15548381 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp51 cytochrome P450, family 51 increases expression EXP Hexachlorocyclohexane results in increased expression of CYP51 mRNA CTD PMID:17785943 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Dap3 death associated protein 3 increases expression ISO Hexachlorocyclohexane results in increased expression of DAP3 mRNA CTD PMID:23777605 NCBI chr 2:188,225,607...188,255,324
Ensembl chr 2:188,225,613...188,252,725
JBrowse link
G Dcn decorin decreases expression EXP Hexachlorocyclohexane results in decreased expression of DCN mRNA CTD PMID:17785943 NCBI chr 7:38,742,250...38,782,282
Ensembl chr 7:38,742,051...38,782,323
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Hexachlorocyclohexane results in increased expression of DNAJB4 mRNA CTD PMID:24356939 NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
JBrowse link
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 decreases expression EXP Hexachlorocyclohexane results in decreased expression of DNAJC5 mRNA CTD PMID:17785943 NCBI chr 3:177,012,714...177,047,787
Ensembl chr 3:177,013,604...177,043,902
JBrowse link
G Drd2 dopamine receptor D2 increases expression EXP Hexachlorocyclohexane results in increased expression of DRD2 mRNA CTD PMID:25572523 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of DUSP1 mRNA CTD PMID:17785943 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Hexachlorocyclohexane results in increased expression of DUSP10 mRNA CTD PMID:24356939 NCBI chr13:104,284,660...104,321,455
Ensembl chr13:104,284,660...104,321,455
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression EXP Hexachlorocyclohexane affects the expression of EEF1A1 mRNA CTD PMID:22001173 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Egr1 early growth response 1 increases expression EXP Hexachlorocyclohexane results in increased expression of EGR1 mRNA CTD PMID:17785943 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif2b3 eukaryotic translation initiation factor 2B subunit gamma affects expression EXP Hexachlorocyclohexane affects the expression of EIF2B3 mRNA CTD PMID:22001173 NCBI chr 5:135,882,946...135,949,276
Ensembl chr 5:135,882,967...135,949,818
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B subunit delta affects expression EXP Hexachlorocyclohexane affects the expression of EIF2B4 mRNA CTD PMID:22001173 NCBI chr 6:26,546,917...26,552,474
Ensembl chr 6:26,546,924...26,552,430
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression EXP Hexachlorocyclohexane results in increased expression of EIF5 mRNA CTD PMID:17785943 NCBI chr 6:136,002,983...136,011,409
Ensembl chr 6:136,004,214...136,011,406
JBrowse link
G Epha3 Eph receptor A3 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA3 mRNA CTD PMID:28263720 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Epha8 Eph receptor A8 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of EPHA8 mRNA CTD PMID:28263720 NCBI chr 5:155,293,731...155,321,016
Ensembl chr 5:155,295,314...155,316,495
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
affects binding
decreases expression
ISO [DDT analog co-treated with Hexachlorocyclohexane analog co-treated with Chlorobenzenes co-treated with Mirex co-treated with Polychlorinated Biphenyls co-treated with Chlordan co-treated with Toxaphene co-treated with Aldrin co-treated with Dieldrin] results in increased expression of ESR1 mRNA; [Hexachlorocyclohexane co-treated with DDT] results in increased expression of ESR1; Hexachlorocyclohexane inhibits the reaction [Estradiol binds to ESR1 protein]
Hexachlorocyclohexane results in increased activity of ESR1 protein
Hexachlorocyclohexane binds to ESR1 protein
Hexachlorocyclohexane results in decreased expression of ESR1 protein
Hexachlorocyclohexane binds to and results in increased activity of ESR1 protein
CTD PMID:14579009 PMID:15253041 PMID:16329587 PMID:20209442 PMID:21278053 PMID:21295777 PMID:26022396 PMID:26139245 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO Hexachlorocyclohexane results in increased activity of ESR2 protein CTD PMID:15064155 PMID:26139245 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrra estrogen related receptor, alpha increases expression ISO Hexachlorocyclohexane results in increased expression of ESRRA mRNA CTD PMID:23777605 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Evi2a ecotropic viral integration site 2A increases expression ISO Hexachlorocyclohexane results in increased expression of EVI2A mRNA CTD PMID:24356939 NCBI chr10:66,870,048...66,873,948
Ensembl chr10:66,870,067...66,873,948
JBrowse link
G Fam107b family with sequence similarity 107, member B increases expression ISO Hexachlorocyclohexane results in increased expression of FAM107B mRNA CTD PMID:24356939 NCBI chr17:78,489,667...78,689,933
Ensembl chr17:78,489,668...78,561,613
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP Hexachlorocyclohexane results in increased expression of FAS protein CTD PMID:19038305 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression EXP Hexachlorocyclohexane results in increased expression of FASLG protein CTD PMID:19038305 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase affects activity EXP Hexachlorocyclohexane affects the activity of FASN protein CTD PMID:7535533 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Hexachlorocyclohexane results in increased expression of FBXO32 mRNA CTD PMID:24356939 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fkbp3 FKBP prolyl isomerase 3 affects expression EXP Hexachlorocyclohexane affects the expression of FKBP3 mRNA CTD PMID:17785943 NCBI chr 6:86,810,865...86,822,115
Ensembl chr 6:86,810,809...86,822,094
JBrowse link
G Fn1 fibronectin 1 affects expression EXP Hexachlorocyclohexane affects the expression of FN1 mRNA CTD PMID:17785943 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO
EXP
Hexachlorocyclohexane results in increased expression of FOS mRNA
alpha-hexachlorocyclohexane inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS mRNA]; delta-hexachlorocyclohexane inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS mRNA]; delta-hexachlorocyclohexane inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS protein]; Diazepam inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS mRNA]; Diazepam inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS protein]; Nifedipine inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS protein]; tetrandrine inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS mRNA]
Hexachlorocyclohexane results in increased expression of FOS mRNA; Hexachlorocyclohexane results in increased expression of FOS protein
W 7 inhibits the reaction [Hexachlorocyclohexane results in increased expression of FOS mRNA]
CTD PMID:1380685 PMID:1710164 PMID:7531829 PMID:7534335 PMID:10072926 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa1 forkhead box A1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of FOXA1 mRNA CTD PMID:17785943 NCBI chr 6:78,516,579...78,549,669
Ensembl chr 6:78,545,804...78,549,669
JBrowse link
G Frat1 FRAT regulator of WNT signaling pathway 1 increases expression ISO Hexachlorocyclohexane results in increased expression of FRAT1 mRNA CTD PMID:24356939 NCBI chr 1:261,071,965...261,075,244 JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased expression of CYP11A1 protein]; Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased expression of STAR protein]; Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased phosphorylation of and affects the localization of GJA1 protein] CTD PMID:15749814 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase affects activity
increases activity
EXP Hexachlorocyclohexane affects the activity of G6PD protein
Hexachlorocyclohexane results in increased activity of G6PD protein
CTD PMID:2461408 PMID:7535533 PMID:8519523 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of GABARAPL2 mRNA CTD PMID:17785943 NCBI chr19:44,164,935...44,175,771
Ensembl chr19:44,164,935...44,175,770
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions
increases expression
ISO
EXP
Hexachlorocyclohexane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
Hexachlorocyclohexane results in increased expression of GABRA1 mRNA
CTD PMID:9316872 PMID:11156579 PMID:14637376 PMID:25572523 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 multiple interactions ISO Hexachlorocyclohexane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:14637376 NCBI chr14:39,662,411...39,801,082
Ensembl chr14:39,661,968...39,798,302
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 multiple interactions ISO Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]] CTD PMID:9316872 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 affects binding
multiple interactions
ISO Hexachlorocyclohexane binds to GABRB1 protein
Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]
CTD PMID:11156579 PMID:11489356 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO Hexachlorocyclohexane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]] CTD PMID:14637376 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 affects binding
multiple interactions
ISO Hexachlorocyclohexane binds to GABRB3 protein
Hexachlorocyclohexane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]
CTD PMID:9316872 PMID:11312652 PMID:11489356 PMID:16537435 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO Hexachlorocyclohexane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Pentobarbital results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] CTD PMID:9316872 PMID:11156579 PMID:14637376 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 affects binding ISO Hexachlorocyclohexane binds to GABRR1 protein CTD PMID:11879973 NCBI chr 5:48,374,048...48,411,170
Ensembl chr 5:48,374,096...48,411,170
JBrowse link
G Gata3 GATA binding protein 3 increases expression ISO Hexachlorocyclohexane results in increased expression of GATA3 mRNA CTD PMID:24356939 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gck glucokinase increases expression EXP Hexachlorocyclohexane results in increased expression of GCK mRNA CTD PMID:17785943 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Hexachlorocyclohexane results in increased expression of GCLC mRNA CTD PMID:26198647 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Hexachlorocyclohexane results in increased expression of GCLM mRNA CTD PMID:26198647 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of GFRA1 mRNA CTD PMID:28263720 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions
affects activity
decreases activity
increases activity
ISO
EXP
Plant Extracts inhibits the reaction [Hexachlorocyclohexane results in increased activity of GGT1 protein]
Hexachlorocyclohexane affects the activity of GGT1 protein
Hexachlorocyclohexane results in decreased activity of GGT1 protein
CTD PMID:8519523 PMID:9475050 PMID:11349524 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gja1 gap junction protein, alpha 1 affects localization
decreases phosphorylation
decreases expression
increases degradation
increases phosphorylation
multiple interactions
ISO
EXP
Hexachlorocyclohexane affects the localization of GJA1 protein
Hexachlorocyclohexane results in decreased phosphorylation of GJA1 protein
Hexachlorocyclohexane results in decreased expression of GJA1 mRNA; Hexachlorocyclohexane results in decreased expression of GJA1 protein
Hexachlorocyclohexane results in increased degradation of GJA1 protein modified form
Hexachlorocyclohexane results in increased phosphorylation of GJA1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of GJA1 protein]; chaetoglobosins inhibits the reaction [Hexachlorocyclohexane results in decreased phosphorylation of GJA1 protein]; Chloroquine inhibits the reaction [Hexachlorocyclohexane results in increased degradation of GJA1 protein modified form]; Colchicine inhibits the reaction [Hexachlorocyclohexane results in increased degradation of GJA1 protein modified form]; Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased phosphorylation of and affects the localization of GJA1 protein]; Hexachlorocyclohexane promotes the reaction [GJA1 protein binds to TJP1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Hexachlorocyclohexane affects the localization of GJA1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of GJA1 protein]
CTD PMID:7530866 PMID:8824497 PMID:11532877 PMID:12807735 PMID:15194225 PMID:15749814 PMID:18040759 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glra1 glycine receptor, alpha 1 decreases activity ISO Hexachlorocyclohexane results in decreased activity of GLRA1 protein CTD PMID:22035056 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link
G Glra2 glycine receptor, alpha 2 decreases activity ISO Hexachlorocyclohexane results in decreased activity of GLRA2 protein CTD PMID:22035056 NCBI chr  X:30,612,894...30,832,078
Ensembl chr  X:30,612,903...30,831,483
JBrowse link
G Glra3 glycine receptor, alpha 3 decreases activity ISO Hexachlorocyclohexane results in decreased activity of GLRA3 protein CTD PMID:22035056 NCBI chr16:37,676,959...37,908,221
Ensembl chr16:37,676,962...38,063,821
JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Hexachlorocyclohexane results in decreased expression of GLUL mRNA CTD PMID:17785943 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Glyat glycine-N-acyltransferase affects expression EXP Hexachlorocyclohexane affects the expression of GLYAT mRNA CTD PMID:17785943 NCBI chr 1:229,060,125...229,081,113
Ensembl chr 1:229,063,714...229,080,410
JBrowse link
G Gna12 G protein subunit alpha 12 affects expression EXP Hexachlorocyclohexane affects the expression of GNA12 mRNA CTD PMID:17785943 NCBI chr12:15,890,202...15,971,212
Ensembl chr12:15,890,170...15,971,212
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with DDT] results in increased expression of GNRH1 CTD PMID:16329587 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression EXP Hexachlorocyclohexane results in increased expression of GOT1 mRNA CTD PMID:17785943 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Hexachlorocyclohexane results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpr18 G protein-coupled receptor 18 increases expression ISO Hexachlorocyclohexane results in increased expression of GPR18 mRNA CTD PMID:23824090 PMID:24356939 NCBI chr15:108,323,157...108,326,907
Ensembl chr15:108,323,179...108,326,907
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
EXP [Hexachlorocyclohexane co-treated with isoproturon] results in increased activity of GPT protein
Hexachlorocyclohexane results in increased activity of GPT protein
CTD PMID:11180283 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Hexachlorocyclohexane results in increased expression of GPT2 mRNA CTD PMID:24356939 NCBI chr19:22,599,003...22,633,529
Ensembl chr19:22,590,881...22,632,071
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
increases expression
decreases activity
increases activity
ISO
EXP
[Hexachlorocyclohexane co-treated with Malathion] results in decreased activity of GSR protein; [Hexachlorocyclohexane co-treated with Permethrin] results in decreased activity of GSR protein; Plant Extracts inhibits the reaction [Hexachlorocyclohexane results in decreased activity of GSR protein]
Hexachlorocyclohexane results in increased expression of GSR mRNA
Hexachlorocyclohexane results in increased activity of GSR protein
[Hexachlorocyclohexane co-treated with alpha-hexachlorocyclohexane co-treated with beta-hexachlorocyclohexane co-treated with delta-hexachlorocyclohexane] results in increased activity of GSR protein; [Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of GSR protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of GSR protein; [Phenobarbital co-treated with Hexachlorocyclohexane] results in increased activity of GSR protein; Curcumin inhibits the reaction [Hexachlorocyclohexane results in decreased activity of GSR protein]; Plant Extracts inhibits the reaction [Hexachlorocyclohexane results in decreased activity of GSR protein]
CTD PMID:1716606 PMID:9704597 PMID:10817630 PMID:11349524 PMID:11404799 PMID:11561191 PMID:16046044 PMID:16718366 PMID:21976817 PMID:22224058 PMID:26198647 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 affects expression EXP Hexachlorocyclohexane affects the expression of GSTA2 mRNA CTD PMID:22001173 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression EXP Hexachlorocyclohexane results in increased expression of GSTA5 mRNA CTD PMID:17785943 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gusb glucuronidase, beta affects activity EXP Hexachlorocyclohexane affects the activity of GUSB protein CTD PMID:8519523 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Hbe2 hemoglobin, epsilon 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of HBG2 protein CTD PMID:7512143 NCBI chr 1:169,000,133...169,001,761
Ensembl chr 1:169,000,133...169,001,761
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Hexachlorocyclohexane results in decreased expression of HMGCS1 mRNA CTD PMID:24356939 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha affects expression EXP Hexachlorocyclohexane affects the expression of HNF4A mRNA CTD PMID:17785943 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase increases expression EXP Hexachlorocyclohexane results in increased expression of HPD mRNA CTD PMID:17785943 NCBI chr12:38,828,606...38,839,956
Ensembl chr12:38,828,444...38,839,969
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of HPRT1 mRNA CTD PMID:17785943 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 decreases activity EXP Hexachlorocyclohexane results in decreased activity of HSD17B1 protein CTD PMID:11404799 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases activity EXP Hexachlorocyclohexane results in decreased activity of HSD3B1 protein CTD PMID:11404799
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression
multiple interactions
ISO Hexachlorocyclohexane results in decreased expression of HSD3B2 mRNA
Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of HSD3B2 mRNA]
CTD PMID:17080404 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A affects localization ISO Hexachlorocyclohexane affects the localization of HSPA1A protein CTD PMID:12919956 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases expression EXP Hexachlorocyclohexane results in increased expression of HSPA4 protein CTD PMID:30248393 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases expression EXP Hexachlorocyclohexane results in increased expression of HTR2A mRNA CTD PMID:25572523 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO Hexachlorocyclohexane results in decreased expression of HYLS1 mRNA CTD PMID:24356939 NCBI chr 8:36,763,470...36,772,199
Ensembl chr 8:36,763,481...36,764,422
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO Hexachlorocyclohexane results in decreased expression of ID1 mRNA CTD PMID:24356939 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 affects expression EXP Hexachlorocyclohexane affects the expression of IDH1 mRNA CTD PMID:17785943 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Ier3 immediate early response 3 increases expression ISO Hexachlorocyclohexane results in increased expression of IER3 mRNA CTD PMID:24356939 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifng interferon gamma decreases expression ISO Hexachlorocyclohexane results in decreased expression of IFNG protein CTD PMID:15319175 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of IGF1 mRNA CTD PMID:17785943 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
EXP alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A protein]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A protein]
Hexachlorocyclohexane results in increased expression of IL1A mRNA; Hexachlorocyclohexane results in increased expression of IL1A protein
CTD PMID:15025948 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il5 interleukin 5 decreases expression ISO Hexachlorocyclohexane results in decreased expression of IL5 protein CTD PMID:15319175 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Irs1 insulin receptor substrate 1 decreases phosphorylation EXP Hexachlorocyclohexane results in decreased phosphorylation of IRS1 protein CTD PMID:30248393 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Isl2 ISL LIM homeobox 2 increases expression ISO Hexachlorocyclohexane results in increased expression of ISL2 mRNA CTD PMID:24356939 NCBI chr 8:60,117,565...60,122,716
Ensembl chr 8:60,117,729...60,122,211
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation
multiple interactions
ISO
EXP
Hexachlorocyclohexane results in increased phosphorylation of JUN protein
Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of JUN protein
CTD PMID:15888667 PMID:23927878 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kif21b kinesin family member 21B increases expression ISO Hexachlorocyclohexane results in increased expression of KIF21B mRNA CTD PMID:24356939 NCBI chr13:52,976,505...53,026,750
Ensembl chr13:52,976,507...53,023,103
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of KIT mRNA CTD PMID:28263720 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression EXP Hexachlorocyclohexane results in increased expression of KLF9 mRNA CTD PMID:17785943 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Klhl24 kelch-like family member 24 increases expression ISO Hexachlorocyclohexane results in increased expression of KLHL24 mRNA CTD PMID:24356939 NCBI chr11:84,613,101...84,643,674
Ensembl chr11:84,615,760...84,633,504
JBrowse link
G Ldha lactate dehydrogenase A decreases expression ISO Hexachlorocyclohexane results in decreased expression of LDHA protein CTD PMID:6164129 NCBI chr 1:102,900,288...102,909,713
Ensembl chr 1:102,900,286...102,909,707
JBrowse link
G Ldhb lactate dehydrogenase B decreases expression ISO Hexachlorocyclohexane results in decreased expression of LDHB protein CTD PMID:6164129 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lep leptin affects expression EXP Hexachlorocyclohexane affects the expression of LEP mRNA CTD PMID:17785943 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression EXP Hexachlorocyclohexane results in decreased expression of LHCGR protein CTD PMID:11250058 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Hexachlorocyclohexane results in increased expression of LIF mRNA CTD PMID:26198647 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lrrc2 leucine rich repeat containing 2 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of LRRC2 mRNA CTD PMID:28263720 NCBI chr 8:119,226,651...119,259,649
Ensembl chr 8:119,228,612...119,259,645
JBrowse link
G Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 increases expression EXP Hexachlorocyclohexane results in increased expression of XLKD1 mRNA CTD PMID:17785943 NCBI chr 1:175,663,266...175,676,699
Ensembl chr 1:175,663,266...175,676,699
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression EXP Hexachlorocyclohexane results in increased expression of MAP1LC3B mRNA CTD PMID:17785943 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAP2K1 protein CTD PMID:15888667 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions ISO Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAP2K2 protein CTD PMID:15888667 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 decreases expression EXP Hexachlorocyclohexane results in decreased expression of MAP4K4 mRNA CTD PMID:17785943 NCBI chr 9:46,657,444...46,782,545
Ensembl chr 9:46,657,575...46,782,545
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
calphostin C inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK1 protein]; Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK1 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK1 protein]; AG 1879 inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK1 protein]; Hexachlorocyclohexane inhibits the reaction [Estradiol results in increased phosphorylation of MAPK1 protein]; Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD PMID:12807735 PMID:15888667 PMID:16818664 PMID:18040759 PMID:21278053 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
calphostin C inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK3 protein]; Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK3 protein]; AG 1879 inhibits the reaction [Hexachlorocyclohexane results in increased phosphorylation of MAPK3 protein]; Hexachlorocyclohexane inhibits the reaction [Estradiol results in increased phosphorylation of MAPK3 protein]; Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD PMID:12807735 PMID:15888667 PMID:16818664 PMID:18040759 PMID:21278053 PMID:23927878 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:23927878 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of MAPK9 protein CTD PMID:23927878 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mbp myelin basic protein decreases expression
affects expression
EXP Hexachlorocyclohexane results in decreased expression of MBP protein
Hexachlorocyclohexane affects the expression of MBP mRNA
CTD PMID:1701514 PMID:22954530 NCBI chr18:79,326,738...79,437,310
Ensembl chr18:79,326,738...79,437,310
JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 increases expression EXP Hexachlorocyclohexane results in increased expression of MBTPS2 mRNA CTD PMID:17785943 NCBI chr  X:40,258,933...40,309,047
Ensembl chr  X:40,258,493...40,310,563
JBrowse link
G Meox2 mesenchyme homeobox 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of MEOX2 mRNA CTD PMID:17785943 NCBI chr 6:56,625,768...56,689,195
Ensembl chr 6:56,625,650...56,689,238
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of MERTK mRNA CTD PMID:28263720 NCBI chr 3:121,235,230...121,340,932
Ensembl chr 3:121,235,119...121,342,444
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
EXP [Hexachlorocyclohexane co-treated with Iron] results in increased activity of MPO protein; [Triiodothyronine co-treated with Hexachlorocyclohexane] results in increased activity of MPO protein
Hexachlorocyclohexane results in increased activity of MPO protein
CTD PMID:7503757 PMID:11141352 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of MSH2 mRNA CTD PMID:17785943 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Hexachlorocyclohexane results in increased expression of MT1A mRNA CTD PMID:17785943 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mtch2 mitochondrial carrier 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of MTCH2 mRNA CTD PMID:17785943 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression ISO Hexachlorocyclohexane results in increased expression of MTHFD2 mRNA CTD PMID:24356939 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression EXP Hexachlorocyclohexane results in decreased expression of MYC mRNA CTD PMID:17785943 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh3 myosin heavy chain 3 affects expression EXP Hexachlorocyclohexane affects the expression of MYH3 mRNA CTD PMID:17785943 NCBI chr10:53,621,375...53,645,194
Ensembl chr10:53,621,375...53,645,194
JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 decreases expression ISO Hexachlorocyclohexane results in decreased expression of NANOS1 mRNA CTD PMID:24356939 NCBI chr 1:282,134,676...282,140,370
Ensembl chr 1:282,134,981...282,135,772
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 increases expression ISO Hexachlorocyclohexane results in increased expression of NCOA7 mRNA CTD PMID:24356939 NCBI chr 1:29,225,727...29,386,642
Ensembl chr 1:29,225,707...29,385,199
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of NFE2L2 mRNA CTD PMID:17785943 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfe2l3 nuclear factor, erythroid 2-like 3 decreases expression ISO Hexachlorocyclohexane results in decreased expression of NFE2L3 mRNA CTD PMID:24356939 NCBI chr 4:81,205,214...81,233,068
Ensembl chr 4:81,205,404...81,232,813
JBrowse link
G Nfia nuclear factor I/A decreases expression EXP Hexachlorocyclohexane results in decreased expression of NFIA mRNA CTD PMID:17785943 NCBI chr 5:116,421,895...116,750,381
Ensembl chr 5:116,420,690...116,751,416
JBrowse link
G Nfib nuclear factor I/B decreases expression EXP Hexachlorocyclohexane results in decreased expression of NFIB mRNA CTD PMID:17785943 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nfix nuclear factor I X increases expression EXP Hexachlorocyclohexane results in increased expression of NFIX mRNA CTD PMID:17785943 NCBI chr19:25,818,640...25,914,777
Ensembl chr19:25,821,780...25,914,696
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases phosphorylation
increases activity
EXP alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased activity of NFKB1 protein]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased activity of NFKB1 protein]; Hexachlorocyclohexane affects the reaction [Triiodothyronine results in increased activity of NFKB1 protein]
Hexachlorocyclohexane results in increased phosphorylation of NFKB1 protein
CTD PMID:15019085 PMID:15025948 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation EXP Hexachlorocyclohexane results in increased phosphorylation of NFKBIA protein CTD PMID:30248393 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nipbl NIPBL, cohesin loading factor increases expression EXP Hexachlorocyclohexane results in increased expression of NIPBL mRNA CTD PMID:17785943 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820
JBrowse link
G Nop58 NOP58 ribonucleoprotein increases expression EXP Hexachlorocyclohexane results in increased expression of NOL5 mRNA CTD PMID:17785943 NCBI chr 9:66,495,881...66,520,521
Ensembl chr 9:66,495,832...66,519,788
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO Hexachlorocyclohexane results in increased expression of NOS2 protein CTD PMID:23777605 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP [Hexachlorocyclohexane co-treated with Dieldrin] results in decreased expression of NOX1 protein CTD PMID:30240590 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression EXP Hexachlorocyclohexane results in increased expression of NR0B2 mRNA CTD PMID:17785943 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases expression
increases activity
EXP
ISO
Hexachlorocyclohexane binds to and results in increased activity of NR1I2 protein
Hexachlorocyclohexane results in increased expression of NR1I2 mRNA
Hexachlorocyclohexane results in increased activity of NR1I2 protein
CTD PMID:14613717 PMID:15548381 PMID:16054614 PMID:25572523 PMID:25680588 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
increases activity
EXP
ISO
Hexachlorocyclohexane results in increased expression of NR1I3 mRNA
Hexachlorocyclohexane results in increased activity of NR1I3 protein
CTD PMID:25572523 PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 affects expression EXP Hexachlorocyclohexane affects the expression of NR2F6 mRNA CTD PMID:17785943 NCBI chr16:19,769,968...19,777,414
Ensembl chr16:19,769,968...19,777,414
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression EXP Hexachlorocyclohexane results in increased expression of NR3C1 mRNA CTD PMID:17785943 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression EXP Hexachlorocyclohexane results in increased expression of NR4A2 mRNA CTD PMID:8737662 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression ISO Hexachlorocyclohexane results in increased expression of NRF1 mRNA CTD PMID:23777605 NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK1 mRNA CTD PMID:28263720 NCBI chr 2:187,143,568...187,160,373
Ensembl chr 2:187,143,568...187,160,373
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of NTRK2 mRNA CTD PMID:28263720 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases activity
increases expression
EXP Diazepam inhibits the reaction [Hexachlorocyclohexane results in increased activity of ODC1 protein]; Diazepam inhibits the reaction [Hexachlorocyclohexane results in increased expression of ODC1 mRNA] CTD PMID:1710164 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase increases expression EXP Hexachlorocyclohexane results in increased expression of OGT mRNA CTD PMID:17785943 NCBI chr  X:71,540,870...71,585,906
Ensembl chr  X:71,528,988...71,585,908
JBrowse link
G Onecut1 one cut homeobox 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of ONECUT1 mRNA CTD PMID:17785943 NCBI chr 8:81,765,779...81,799,894
Ensembl chr 8:81,766,041...81,793,577
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of P4HA1 mRNA CTD PMID:17785943 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Pdcd4 programmed cell death 4 increases expression ISO Hexachlorocyclohexane results in increased expression of PDCD4 mRNA CTD PMID:24356939 NCBI chr 1:274,616,625...274,648,204
Ensembl chr 1:274,625,224...274,648,204
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in increased expression of PDGFRB mRNA CTD PMID:28263720 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of PDLIM1 mRNA CTD PMID:17785943 NCBI chr 1:259,308,326...259,357,006
Ensembl chr 1:259,308,296...259,357,056
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 increases expression ISO Hexachlorocyclohexane results in increased expression of PELI1 mRNA CTD PMID:24356939 NCBI chr14:106,008,086...106,062,566
Ensembl chr14:106,008,086...106,061,641
JBrowse link
G Per2 period circadian regulator 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of PER2 mRNA CTD PMID:17785943 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Pgd phosphogluconate dehydrogenase affects activity EXP Hexachlorocyclohexane affects the activity of PGD protein CTD PMID:7535533 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgr progesterone receptor affects binding
multiple interactions
ISO Hexachlorocyclohexane binds to PGR protein
[Progesterone co-treated with Hexachlorocyclohexane] results in decreased expression of PGR mRNA; Hexachlorocyclohexane inhibits the reaction [16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased activity of PGR protein]; Hexachlorocyclohexane inhibits the reaction [Progesterone binds to PGR protein]
CTD PMID:9144411 PMID:14579009 PMID:26022396 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pigr polymeric immunoglobulin receptor increases expression EXP Hexachlorocyclohexane results in increased expression of PIGR mRNA CTD PMID:17785943 NCBI chr13:47,564,176...47,592,093
Ensembl chr13:47,572,219...47,591,699
JBrowse link
G Pja2 praja ring finger ubiquitin ligase 2 increases expression EXP Hexachlorocyclohexane results in increased expression of PJA2 mRNA CTD PMID:17785943 NCBI chr 9:111,998,204...112,048,847
Ensembl chr 9:111,998,203...112,027,240
JBrowse link
G Plaat5 phospholipase A and acyltransferase 5 decreases expression EXP Hexachlorocyclohexane results in decreased expression of PLAAT5 mRNA CTD PMID:17785943 NCBI chr 1:222,907,159...222,937,643
Ensembl chr 1:222,907,159...222,937,633
JBrowse link
G Plcl1 phospholipase C-like 1 increases expression ISO Hexachlorocyclohexane results in increased expression of PLCL1 mRNA CTD PMID:24356939 NCBI chr 9:62,016,112...62,349,244
Ensembl chr 9:62,291,405...62,349,309
JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression EXP Hexachlorocyclohexane results in increased expression of PLPP3 mRNA CTD PMID:17785943 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Plxnd1 plexin D1 multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of PLXND1 mRNA CTD PMID:28263720 NCBI chr 4:147,854,309...147,894,170
Ensembl chr 4:147,854,309...147,893,992
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 increases expression ISO Hexachlorocyclohexane results in increased expression of PNRC1 mRNA CTD PMID:24356939 NCBI chr 5:48,501,472...48,504,511
Ensembl chr 5:48,501,472...48,504,511
JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit increases expression EXP Hexachlorocyclohexane results in increased expression of POLG2 mRNA CTD PMID:17785943 NCBI chr10:94,968,836...94,979,259
Ensembl chr10:94,968,836...94,979,259
JBrowse link
G Pomc proopiomelanocortin multiple interactions ISO [Hexachlorocyclohexane co-treated with DDT] results in increased expression of POMC CTD PMID:16329587 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Hexachlorocyclohexane results in increased expression of POR mRNA CTD PMID:17785943 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Hexachlorocyclohexane results in increased expression of PPARGC1A mRNA CTD PMID:23777605 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression EXP Hexachlorocyclohexane results in decreased expression of PPP2R2B mRNA CTD PMID:17785943 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Pprc1 PPARG related coactivator 1 increases expression ISO Hexachlorocyclohexane results in increased expression of PPRC1 mRNA CTD PMID:23777605 NCBI chr 1:265,809,892...265,826,319
Ensembl chr 1:265,809,754...265,826,306
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta affects expression EXP Hexachlorocyclohexane affects the expression of PRKACB mRNA CTD PMID:17785943 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Prkch protein kinase C, eta affects expression EXP Hexachlorocyclohexane affects the expression of PRKCH mRNA CTD PMID:22001173 NCBI chr 6:96,479,243...96,677,368
Ensembl chr 6:96,479,430...96,676,225
JBrowse link
G Prxl2b peroxiredoxin like 2B decreases expression ISO Hexachlorocyclohexane results in decreased expression of PRXL2B mRNA CTD PMID:24356939 NCBI chr 5:172,304,799...172,307,402
Ensembl chr 5:172,304,758...172,307,431
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 decreases expression EXP Hexachlorocyclohexane results in decreased expression of PSMB3 mRNA CTD PMID:17785943 NCBI chr10:85,646,646...85,653,729
Ensembl chr10:85,646,633...85,653,729
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
EXP Hexachlorocyclohexane results in increased expression of and results in increased activity of PTGS2 protein
Hexachlorocyclohexane results in increased expression of PTGS2 mRNA; Hexachlorocyclohexane results in increased expression of PTGS2 protein
CTD PMID:10426785 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression EXP Hexachlorocyclohexane results in increased expression of PTP4A1 mRNA CTD PMID:17785943 NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
Ensembl chr 9:37,223,729...37,231,291
JBrowse link
G Rab14 RAB14, member RAS oncogene family increases expression EXP Hexachlorocyclohexane results in increased expression of RAB14 mRNA CTD PMID:17785943 NCBI chr 3:14,373,270...14,395,357
Ensembl chr 3:14,373,275...14,395,362
JBrowse link
G Rab34 RAB34, member RAS oncogene family affects expression EXP Hexachlorocyclohexane affects the expression of RAB34 mRNA CTD PMID:17785943 NCBI chr10:65,448,111...65,452,178
Ensembl chr10:65,448,950...65,452,177
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression EXP Hexachlorocyclohexane results in decreased expression of RAD23A mRNA CTD PMID:17785943 NCBI chr19:25,949,488...25,956,677
Ensembl chr19:25,949,490...25,955,391
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO Hexachlorocyclohexane results in increased phosphorylation of and results in increased activity of RAF1 protein CTD PMID:15888667 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rala RAS like proto-oncogene A increases expression EXP Hexachlorocyclohexane results in increased expression of RALA mRNA CTD PMID:17785943 NCBI chr17:49,676,073...49,729,133
Ensembl chr17:49,714,294...49,727,664
JBrowse link
G Ralgapa1 Ral GTPase activating protein catalytic subunit alpha 1 increases expression EXP Hexachlorocyclohexane results in increased expression of RALGAPA1 mRNA CTD PMID:17785943 NCBI chr 6:76,386,971...76,661,530
Ensembl chr 6:76,396,784...76,608,864
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO Hexachlorocyclohexane results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of RB1 mRNA CTD PMID:17785943 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Rbm10 RNA binding motif protein 10 decreases expression EXP Hexachlorocyclohexane results in decreased expression of RBM10 mRNA CTD PMID:17785943 NCBI chr  X:1,754,869...1,786,973
Ensembl chr  X:1,754,861...1,786,978
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases activity
increases phosphorylation
affects localization
EXP alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased activity of RELA protein]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased activity of RELA protein]; Hexachlorocyclohexane affects the reaction [Triiodothyronine results in increased activity of RELA protein]
Hexachlorocyclohexane results in increased phosphorylation of RELA protein
Hexachlorocyclohexane affects the localization of RELA protein
CTD PMID:15019085 PMID:15025948 PMID:19038305 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ret ret proto-oncogene multiple interactions ISO [Hexachlorocyclohexane co-treated with Aldrin co-treated with Dieldrin co-treated with Endrin co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Dichlorodiphenyldichloroethane co-treated with DDT co-treated with Simvastatin] results in decreased expression of RET mRNA CTD PMID:28263720 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G RGD1305464 similar to human chromosome 15 open reading frame 39 decreases expression ISO Hexachlorocyclohexane results in decreased expression of C15ORF39 mRNA CTD PMID:24356939 NCBI chr 8:61,913,588...61,923,149
Ensembl chr 8:61,913,589...61,919,874
JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression ISO Hexachlorocyclohexane results in decreased expression of RGS2 mRNA CTD PMID:24356939 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rnpep arginyl aminopeptidase decreases expression EXP Hexachlorocyclohexane results in decreased expression of RNPEP mRNA CTD PMID:17785943 NCBI chr13:52,092,863...52,124,006
Ensembl chr13:52,092,859...52,111,363
JBrowse link
G Rps15 ribosomal protein S15 decreases expression EXP Hexachlorocyclohexane results in decreased expression of RPS15 mRNA CTD PMID:17785943 NCBI chr 7:12,282,134...12,283,573
Ensembl chr 7:12,282,109...12,283,608
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of RSAD2 mRNA CTD PMID:17785943 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Rxra retinoid X receptor alpha affects expression EXP Hexachlorocyclohexane affects the expression of RXRA mRNA CTD PMID:17785943 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Rxrb retinoid X receptor beta increases activity ISO Hexachlorocyclohexane results in increased activity of RXRB protein CTD PMID:18207673 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G Rxrg retinoid X receptor gamma decreases expression EXP Hexachlorocyclohexane results in decreased expression of RXRG mRNA CTD PMID:17785943 NCBI chr13:85,818,473...85,868,555
Ensembl chr13:85,818,427...85,868,552
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Hexachlorocyclohexane results in decreased expression of SCD1 mRNA CTD PMID:17785943 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sdc4 syndecan 4 increases expression EXP Hexachlorocyclohexane results in increased expression of SDC4 mRNA CTD PMID:17785943 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sec22a SEC22 homolog A, vesicle trafficking protein decreases expression EXP Hexachlorocyclohexane results in decreased expression of SEC22A mRNA CTD PMID:17785943 NCBI chr11:68,633,080...68,686,553
Ensembl chr11:68,633,160...68,686,548
JBrowse link
G Sec31a SEC31 homolog A, COPII coat complex component increases expression EXP Hexachlorocyclohexane results in increased expression of SEC31A mRNA CTD PMID:17785943 NCBI chr14:10,854,713...10,909,579
Ensembl chr14:10,854,682...10,909,612
JBrowse link
G Sema3g semaphorin 3G decreases expression ISO Hexachlorocyclohexane results in decreased expression of SEMA3G mRNA CTD PMID:24356939 NCBI chr16:7,303,582...7,315,214
Ensembl chr16:7,303,578...7,315,390
JBrowse link
G Serinc3 serine incorporator 3 affects expression EXP Hexachlorocyclohexane affects the expression of SERINC3 mRNA CTD PMID:17785943 NCBI chr 3:160,018,643...160,038,078
Ensembl chr 3:160,018,646...160,038,078
JBrowse link
G Serpine2 serpin family E member 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of SERPINE2 mRNA CTD PMID:17785943 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Sesn2 sestrin 2 increases expression ISO Hexachlorocyclohexane results in increased expression of SESN2 mRNA CTD PMID:24356939 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases expression
increases expression
EXP
ISO
Hexachlorocyclohexane results in decreased expression of SGK1 mRNA
Hexachlorocyclohexane results in increased expression of SGK1 mRNA
CTD PMID:17785943 PMID:24356939 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Shbg sex hormone binding globulin multiple interactions
decreases expression
ISO
EXP
Hexachlorocyclohexane inhibits the reaction [Dihydrotestosterone binds to SHBG protein]
Hexachlorocyclohexane results in decreased expression of SHBG protein
CTD PMID:9171990 PMID:18248869 NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
JBrowse link
G Si sucrase-isomaltase decreases activity EXP Hexachlorocyclohexane results in decreased activity of SI protein CTD PMID:92405 NCBI chr 2:170,220,794...170,301,348
Ensembl chr 2:170,221,245...170,301,348
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO Hexachlorocyclohexane results in decreased expression of SLC10A1 mRNA CTD PMID:24464585 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc11a2 solute carrier family 11 member 2 increases expression EXP Hexachlorocyclohexane results in increased expression of SLC11A2 mRNA CTD PMID:17785943 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases activity ISO Hexachlorocyclohexane results in decreased activity of SLC22A1 protein CTD PMID:24464585 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a25 solute carrier family 22, member 25 affects expression EXP Hexachlorocyclohexane affects the expression of SLC22A9 mRNA CTD PMID:17785943 NCBI chr 1:224,596,886...224,698,512
Ensembl chr 1:224,596,887...224,698,514
JBrowse link
G Slc25a30 solute carrier family 25, member 30 decreases expression EXP Hexachlorocyclohexane results in decreased expression of SLC25A30 mRNA CTD PMID:17785943 NCBI chr15:57,811,612...57,834,173
Ensembl chr15:57,813,356...57,834,173
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Hexachlorocyclohexane results in increased expression of SLC3A2 mRNA CTD PMID:24356939 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression EXP Hexachlorocyclohexane results in increased expression of SLC4A4 mRNA CTD PMID:17785943 NCBI chr14:20,476,258...20,817,042
Ensembl chr14:20,479,323...20,920,286
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Hexachlorocyclohexane results in increased expression of SLC7A11 mRNA CTD PMID:24356939 PMID:26198647 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc7a2 solute carrier family 7 member 2 increases expression EXP Hexachlorocyclohexane results in increased expression of SLC7A2 mRNA CTD PMID:17785943 NCBI chr16:54,459,409...54,513,349
Ensembl chr16:54,460,067...54,513,349
JBrowse link
G Snai2 snail family transcriptional repressor 2 affects expression EXP Hexachlorocyclohexane affects the expression of SNAI2 mRNA CTD PMID:17785943 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 increases expression EXP Hexachlorocyclohexane results in increased expression of SNRNP70 mRNA CTD PMID:17785943 NCBI chr 1:101,367,470...101,388,153
Ensembl chr 1:101,367,471...101,388,129
JBrowse link
G Socs2 suppressor of cytokine signaling 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of SOCS2 mRNA CTD PMID:17785943 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Sord sorbitol dehydrogenase affects activity EXP Hexachlorocyclohexane affects the activity of SORD protein CTD PMID:8519523 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of SPRY1 mRNA CTD PMID:17785943 NCBI chr 2:124,400,689...124,405,331
Ensembl chr 2:124,400,679...124,405,331
JBrowse link
G Sqle squalene epoxidase increases expression EXP Hexachlorocyclohexane results in increased expression of SQLE mRNA CTD PMID:17785943 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Hexachlorocyclohexane results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of SREBF1 mRNA CTD PMID:17785943 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 increases expression EXP Hexachlorocyclohexane results in increased expression of SRSF2 mRNA CTD PMID:17785943 NCBI chr10:105,792,779...105,795,986
Ensembl chr10:105,792,779...105,795,958
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Hexachlorocyclohexane results in increased expression of SRXN1 mRNA CTD PMID:26198647 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Stam2 signal transducing adaptor molecule 2 increases expression ISO Hexachlorocyclohexane results in increased expression of STAM2 mRNA CTD PMID:24356939 NCBI chr 3:38,230,676...38,277,433
Ensembl chr 3:38,230,618...38,277,440
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression
increases expression
ISO
EXP
Hexachlorocyclohexane inhibits the reaction [Colforsin results in increased expression of STAR mRNA]
Hexachlorocyclohexane results in decreased expression of STAR protein
Hexachlorocyclohexane results in increased expression of STAR protein
Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased expression of STAR protein]
Hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR mRNA]; Hexachlorocyclohexane inhibits the reaction [Bucladesine results in increased expression of STAR protein]
Hexachlorocyclohexane results in increased expression of STAR mRNA
CTD PMID:10993823 PMID:15749814 PMID:17080404 PMID:18248869 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP Hexachlorocyclohexane results in decreased expression of SULT1A1 mRNA CTD PMID:9566755 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 multiple interactions
decreases expression
ISO
EXP
Hexachlorocyclohexane promotes the reaction [Colforsin results in decreased expression of SULT2A1 mRNA]
Hexachlorocyclohexane results in decreased expression of SULT2A1 mRNA
CTD PMID:9566755 PMID:17080404 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tfam transcription factor A, mitochondrial increases expression ISO Hexachlorocyclohexane results in increased expression of TFAM mRNA CTD PMID:23777605 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tfb2m transcription factor B2, mitochondrial increases expression ISO Hexachlorocyclohexane results in increased expression of TFB2M mRNA CTD PMID:23777605 NCBI chr13:97,820,493...97,838,275
Ensembl chr13:97,820,493...97,838,228
Ensembl chr13:97,820,493...97,838,228
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased expression of CYP11A1 protein]; Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased expression of STAR protein]; Hexachlorocyclohexane inhibits the reaction [[FSHB protein co-treated with TGFB1 protein] results in increased phosphorylation of and affects the localization of GJA1 protein] CTD PMID:15749814 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tjp1 tight junction protein 1 affects localization
multiple interactions
decreases expression
ISO
EXP
Hexachlorocyclohexane affects the localization of TJP1 protein
Hexachlorocyclohexane promotes the reaction [GJA1 protein binds to TJP1 protein]
Hexachlorocyclohexane results in decreased expression of TJP1 protein
CTD PMID:11532877 PMID:15194225 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tm6sf1 transmembrane 6 superfamily member 1 increases expression ISO Hexachlorocyclohexane results in increased expression of TM6SF1 mRNA CTD PMID:24356939 NCBI chr 1:143,657,607...143,703,829
Ensembl chr 1:143,661,521...143,703,759
JBrowse link
G Tmco6 transmembrane and coiled-coil domains 6 decreases expression ISO Hexachlorocyclohexane results in decreased expression of TMCO6 mRNA CTD PMID:24356939 NCBI chr18:29,579,145...29,585,740
Ensembl chr18:29,579,145...29,585,740
JBrowse link
G Tmem177 transmembrane protein 177 decreases expression ISO Hexachlorocyclohexane results in decreased expression of TMEM177 mRNA CTD PMID:24356939 NCBI chr13:35,929,783...35,933,271
Ensembl chr13:35,929,819...35,933,243
JBrowse link
G Tmem267 transmembrane protein 267 increases expression ISO Hexachlorocyclohexane results in increased expression of TMEM267 mRNA CTD PMID:24356939 NCBI chr 2:52,356,449...52,366,075
Ensembl chr 2:52,358,097...52,366,667
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases expression
EXP
ISO
[Triiodothyronine co-treated with Hexachlorocyclohexane] results in increased expression of TNF mRNA; [Triiodothyronine co-treated with Hexachlorocyclohexane] results in increased expression of TNF protein; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF mRNA]; alpha-Tocopherol inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF protein]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF mRNA]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF protein]; Hexachlorocyclohexane inhibits the reaction [Triiodothyronine results in increased expression of TNF protein]
Lindane increases expression of Tnf protein in serum
Hexachlorocyclohexane results in increased expression of TNF mRNA; Hexachlorocyclohexane results in increased expression of TNF protein
Hexachlorocyclohexane results in decreased expression of TNF protein
CTD PMID:15019085 PMID:15025948 PMID:15135310 PMID:15319175, PMID:15019085 RGD:14995431 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnxa-ps1 tenascin XA, pseudogene 1 affects expression EXP Hexachlorocyclohexane affects the expression of TNXA mRNA CTD PMID:17785943 NCBI chr20:4,485,316...4,486,671 JBrowse link
G Tor1aip1 torsin 1A interacting protein 1 increases expression EXP Hexachlorocyclohexane results in increased expression of TOR1AIP1 mRNA CTD PMID:17785943 NCBI chr13:73,670,649...73,704,668
Ensembl chr13:73,670,141...73,704,678
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [Hexachlorocyclohexane co-treated with Estradiol] results in increased expression of TP53 protein CTD PMID:18174961 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpm3 tropomyosin 3 affects expression EXP Hexachlorocyclohexane affects the expression of TPM3 mRNA CTD PMID:17785943 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Tra2b transformer 2 beta homolog affects expression EXP Hexachlorocyclohexane affects the expression of TRA2B mRNA CTD PMID:17785943 NCBI chr11:82,373,828...82,392,208
Ensembl chr11:82,373,870...82,392,083
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Hexachlorocyclohexane results in increased expression of TRIB3 mRNA CTD PMID:24356939 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression EXP Hexachlorocyclohexane results in decreased expression of TUBA4A mRNA CTD PMID:17785943 NCBI chr 9:82,415,599...82,419,918
Ensembl chr 9:82,415,605...82,419,288
JBrowse link
G Txn2 thioredoxin 2 decreases expression EXP Hexachlorocyclohexane results in decreased expression of TXN2 mRNA CTD PMID:17785943 NCBI chr 7:119,144,350...119,158,173
Ensembl chr 7:119,144,351...119,158,201
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase affects expression EXP Hexachlorocyclohexane affects the expression of TYRO3 mRNA CTD PMID:17785943 NCBI chr 3:111,597,102...111,616,142
Ensembl chr 3:111,597,102...111,616,142
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases activity EXP Hexachlorocyclohexane results in increased activity of UGT1A1 protein CTD PMID:16641539 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression EXP Hexachlorocyclohexane results in increased expression of UGT1A6 mRNA CTD PMID:17785943 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Hexachlorocyclohexane results in increased expression of VEGFA mRNA CTD PMID:24356939 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vip vasoactive intestinal peptide decreases response to substance
multiple interactions
EXP Hexachlorocyclohexane results in decreased susceptibility to VIP protein
Hexachlorocyclohexane inhibits the reaction [VIP protein results in increased abundance of Cyclic AMP]
CTD PMID:2467674 PMID:4120787 PMID:20732086 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
G Vldlr very low density lipoprotein receptor increases expression ISO Hexachlorocyclohexane results in increased expression of VLDLR mRNA CTD PMID:24356939 NCBI chr 1:245,236,819...245,273,688
Ensembl chr 1:245,237,736...245,269,205
JBrowse link
G Wasl WASP like actin nucleation promoting factor increases expression EXP Hexachlorocyclohexane results in increased expression of WASL mRNA CTD PMID:17785943 NCBI chr 4:51,677,722...51,726,212
Ensembl chr 4:51,677,722...51,726,212
JBrowse link
G Zfp354a zinc finger protein 354A increases expression EXP Hexachlorocyclohexane results in increased expression of ZFP354A mRNA CTD PMID:17785943 NCBI chr10:36,586,495...36,600,172
Ensembl chr10:36,589,181...36,600,469
JBrowse link
G Zfp628 zinc finger protein 628 decreases expression ISO Hexachlorocyclohexane results in decreased expression of ZNF628 mRNA CTD PMID:24356939 NCBI chr 1:72,465,403...72,474,442
Ensembl chr 1:72,465,341...72,468,738
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      molecular entity 19771
        polyatomic entity 19689
          heteroatomic molecular entity 19619
            halide 18076
              organohalogen compound 17842
                halohydrocarbon 14041
                  chlorohydrocarbon 8758
                    chlorocycloalkane 504
                      chlorocyclohexane + 504
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    main group molecular entity 19665
                      s-block molecular entity 19430
                        hydrogen molecular entity 19424
                          hydrides 18758
                            organic hydride 18356
                              organic fundamental parent 18356
                                hydrocarbon 18076
                                  halohydrocarbon 14041
                                    chlorohydrocarbon 8758
                                      chlorocycloalkane 504
                                        chlorocyclohexane + 504
paths to the root