CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: pyrethrins
Accession: CHEBI:39098
browse the term
Definition: The active insecticidal constituents of Chrysanthemum cinerariifolium flowers.
Synonyms: related_synonym: Pyrethrum
xref: CAS:8003-34-7; KEGG:C14941
xref_mesh: MESH:D011722
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Bax
BCL2 associated X, apoptosis regulator
affects expression
ISO
Pyrethrins affects the expression of BAX protein
CTD
PMID:27939866
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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Bcl2
BCL2, apoptosis regulator
affects expression
ISO
Pyrethrins affects the expression of BCL2 protein
CTD
PMID:27939866
NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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Bdnf
brain-derived neurotrophic factor
multiple interactions
ISO
Pyrethrins inhibits the reaction [Potassium results in increased expression of BDNF mRNA]
CTD
PMID:15527870
NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
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Casp3
caspase 3
increases activity
ISO
Pyrethrins results in increased activity of CASP3 protein
CTD
PMID:27939866
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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Casp9
caspase 9
increases activity
ISO
Pyrethrins results in increased activity of CASP9 protein
CTD
PMID:27939866
NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
Pyrethrins results in increased expression of CYP2B1 mRNA
CTD
PMID:18022748
NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
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Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
increases expression
EXP
Pyrethrins results in increased expression of CYP2B2 mRNA
CTD
PMID:18022748
NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression
ISO
Pyrethrins results in increased expression of CYP2B6 mRNA
CTD
PMID:18022748
NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
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Cyp3a62
cytochrome P450, family 3, subfamily a, polypeptide 62
increases expression
ISO
Pyrethrins results in increased expression of CYP3A4 mRNA
CTD
PMID:18022748
NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
Pyrethrins inhibits the reaction [Potassium results in increased expression of FOS mRNA]
CTD
PMID:15527870
NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
Pyrethrins binds to and results in increased activity of NR1I2 protein
CTD
PMID:21115097
NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
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Parp1
poly (ADP-ribose) polymerase 1
increases cleavage
ISO
Pyrethrins results in increased cleavage of PARP1 protein
CTD
PMID:27939866
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
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Ppara
peroxisome proliferator activated receptor alpha
multiple interactions
ISO
Pyrethrins binds to and results in increased activity of PPARA protein
CTD
PMID:17084873
NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
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