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ONTOLOGY REPORT - ANNOTATIONS
Term:costunolide
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Accession:CHEBI:3900 term browser browse the term
Definition:A germacranolide with anthelminthic, antiparasitic and antiviral activities.
Synonyms:exact_synonym: (3aS,6E,10E,11aR)-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one
 related_synonym: (10S,1R)-3,7-dimethyl-11-methylene-13-oxabicyclo[8.3.0]trideca-2,6-dien-12-one;   (3aS,6E,10E)-3-Methylene-6,10-dimethyl-2,3,3abeta,4,5,8,9,11aalpha-octahydrocyclodeca[b]furan-2-one;   (3aS,6E,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one;   (E,E)-6-alpha-Hydroxygermacra-1(10),4,11(13)-trien-12-oic acid gamma-lactone;   (E,E)-germacra-1(10),4,11(13)-trien-12-oic acid, 6-alpha-hydroxy-gamma-lactone;   Costunlide;   Costunolid;   Costus lactone;   Formula=C15H20O2;   InChI=1S/C15H20O2/c1-10-5-4-6-11(2)9-14-13(8-7-10)12(3)15(16)17-14/h5,9,13-14H,3-4,6-8H2,1-2H3/b10-5+,11-9+/t13-,14+/m0/s1;   InChIKey=HRYLQFBHBWLLLL-AHNJNIBGSA-N;   SMILES=[C@H]12C=C(CCC=C(CC[C@H]2C(C(O1)=O)=C)C)C
 alt_id: CHEBI:545296
 xref: Beilstein:14451 "Beilstein";   CAS:553-21-9 "ChemIDplus";   CAS:553-21-9 "KEGG COMPOUND";   KEGG:C09382;   KNApSAcK:C00003240
 xref_mesh: MESH:C002602
 xref: PMID:11534769 "Europe PMC";   PMID:11912066 "Europe PMC";   PMID:14510592 "ChEMBL";   PMID:18409040 "Europe PMC";   PMID:6476889 "Europe PMC";   Patent:KR20000066932;   Reaxys:14451 "Reaxys";   Wikipedia:Costunolide

show annotations for term's descendants       view all columns           Sort by:
 
costunolide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        biochemical role 19133
          metabolite 19101
            costunolide 6
              3beta-hydroxycostunolide 0
              6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic group 18340
                              organic divalent group 18330
                                organodiyl group 18330
                                  carbonyl group 18217
                                    carbonyl compound 18217
                                      carboxylic ester 13954
                                        lactone 5864
                                          terpene lactone 1742
                                            sesquiterpene lactone 1595
                                              germacranolide 6
                                                costunolide 6
                                                  3beta-hydroxycostunolide 0
                                                  6alpha-hydroxygermacra-1(10),4,11(13)-trien-12-oate 0
paths to the root

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