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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(+)-Pimaric acid
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Accession:CHEBI:39 term browser browse the term
Definition:A diterpenoid that has formula C20H30O2.
Synonyms:related_synonym: Dextropimaric acid;   Formula=C20H30O2;   InChI=1S/C20H30O2/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(21)22/h5,13,15-16H,1,6-12H2,2-4H3,(H,21,22)/t15-,16+,18+,19+,20+/m0/s1;   InChIKey=MHVJRKBZMUDEEV-APQLOABGSA-N;   SMILES=C[C@]1(CC[C@H]2C(CC[C@@H]3[C@]2(C)CCC[C@@]3(C)C(O)=O)=C1)C=C
 xref: CAS:127-27-5;   KEGG:C09159;   KNApSAcK:C00003468
 xref_mesh: MESH:C008911



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(+)-Pimaric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 multiple interactions ISO [pimaric acid co-treated with TNF protein] results in decreased expression of ATF2 protein modified form CTD PMID:22705379 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO pimaric acid inhibits the reaction [JUN protein results in increased expression of FOS protein modified form]; pimaric acid inhibits the reaction [TNF protein results in increased expression of FOS protein] CTD PMID:22705379 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO pimaric acid inhibits the reaction [JUN protein results in increased expression of FOS protein modified form] CTD PMID:22705379 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [pimaric acid co-treated with TNF protein] results in decreased expression of JUND protein CTD PMID:22705379 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 affects response to substance EXP KCNMA1 mRNA affects the susceptibility to pimaric acid CTD PMID:19247476 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO pimaric acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein] CTD PMID:22705379 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO pimaric acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:22705379 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO pimaric acid inhibits the reaction [TNF protein results in increased expression of and results in increased activity of MMP9 protein]; pimaric acid inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA] CTD PMID:22705379 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO pimaric acid inhibits the reaction [TNF protein results in increased expression of RELA protein] CTD PMID:22705379 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [pimaric acid co-treated with TNF protein] results in decreased expression of ATF2 protein modified form; [pimaric acid co-treated with TNF protein] results in decreased expression of JUND protein; pimaric acid inhibits the reaction [TNF protein results in increased expression of and results in increased activity of MMP9 protein]; pimaric acid inhibits the reaction [TNF protein results in increased expression of FOS protein]; pimaric acid inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; pimaric acid inhibits the reaction [TNF protein results in increased expression of RELA protein]; pimaric acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; pimaric acid inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein] CTD PMID:22705379 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      atom 19799
        nonmetal atom 19686
          carbon atom 19609
            organic molecular entity 19609
              isoprenoid 12725
                terpenoid 12295
                  diterpenoid 11518
                    (+)-Pimaric acid 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    main group molecular entity 19698
                      s-block molecular entity 19479
                        hydrogen molecular entity 19471
                          hydrides 18834
                            organic hydride 18348
                              organic fundamental parent 18348
                                hydrocarbon 18059
                                  terpene 12725
                                    diterpene 11518
                                      diterpenoid 11518
                                        (+)-Pimaric acid 10
paths to the root