CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-phenyl-1H-1,2,4-triazole
Accession: CHEBI:38967
browse the term
Definition: A triazole that has formula C8H7N3.
Synonyms: related_synonym: Formula=C8H7N3; InChI=1S/C8H7N3/c1-2-4-8(5-3-1)11-7-9-6-10-11/h1-7H; InChIKey=CGRLXLHYYDSTKR-UHFFFAOYSA-N; SMILES=c1ccc(cc1)-n1cncn1
xref: Beilstein:116495; CAS:13423-60-4
G
Casp3
caspase 3
increases expression increases activity
ISO
deferasirox results in increased expression of CASP3 protein deferasirox results in increased activity of CASP3 protein
CTD
PMID:21439361
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
G
Ccnt1
cyclin T1
multiple interactions
ISO
deferasirox inhibits the reaction [CDK9 protein binds to CCNT1 protein]
CTD
PMID:17631934
NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
G
Cdk2
cyclin dependent kinase 2
decreases activity
ISO
deferasirox results in decreased activity of CDK2 protein
CTD
PMID:17631934
NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
G
Cdk9
cyclin-dependent kinase 9
multiple interactions
ISO
deferasirox inhibits the reaction [CDK9 protein binds to CCNT1 protein]
CTD
PMID:17631934
NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
G
Clu
clusterin
increases expression
EXP
deferasirox results in increased expression of CLU protein
CTD
PMID:21439361
NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
G
Havcr1
hepatitis A virus cellular receptor 1
increases expression
ISO EXP
deferasirox results in increased expression of HAVCR1 protein
CTD
PMID:21439361
NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
G
Lcn2
lipocalin 2
increases expression
ISO EXP
deferasirox results in increased expression of LCN2 protein
CTD
PMID:21439361
NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
G
Polr2a
RNA polymerase II subunit A
decreases phosphorylation
ISO
deferasirox results in decreased phosphorylation of POLR2A protein
CTD
PMID:17631934
NCBI chr10:56,339,277...56,364,888
Ensembl chr10:56,339,284...56,365,084
G
Bdnf
brain-derived neurotrophic factor
decreases expression
EXP
triazophos results in decreased expression of BDNF mRNA; triazophos results in decreased expression of BDNF protein
CTD
PMID:23949197
NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19761
chemical entity
19761
atom
19759
nonmetal atom
19641
nitrogen atom
18572
nitrogen molecular entity
18572
organonitrogen compound
18361
organonitrogen heterocyclic compound
17521
azole
12533
triazoles
3648
1-phenyl-1H-1,2,4-triazole
9
1-phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one
0
1-phenyl-1H-1,2,4-triazol-3-ol +
1
2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol +
8
Path 2
CHEBI ontology
19761
subatomic particle
19759
composite particle
19759
hadron
19759
baryon
19759
nucleon
19759
atomic nucleus
19759
atom
19759
main group element atom
19653
p-block element atom
19653
carbon group element atom
19569
carbon atom
19559
organic molecular entity
19559
organic molecule
19493
organic cyclic compound
19318
organic heterocyclic compound
18510
heteroarene
16517
monocyclic heteroarene
13359
azole
12533
triazoles
3648
1-phenyl-1H-1,2,4-triazole
9
1-phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one
0
1-phenyl-1H-1,2,4-triazol-3-ol +
1
2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol +
8