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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1-phenyl-1H-1,2,4-triazole
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Accession:CHEBI:38967 term browser browse the term
Definition:A triazole that has formula C8H7N3.
Synonyms:related_synonym: Formula=C8H7N3;   InChI=1S/C8H7N3/c1-2-4-8(5-3-1)11-7-9-6-10-11/h1-7H;   InChIKey=CGRLXLHYYDSTKR-UHFFFAOYSA-N;   SMILES=c1ccc(cc1)-n1cncn1
 xref: Beilstein:116495;   CAS:13423-60-4


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deferasirox term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression
increases activity		 ISO deferasirox results in increased expression of CASP3 protein
deferasirox results in increased activity of CASP3 protein		 CTD PMID:21439361 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccnt1 cyclin T1 multiple interactions ISO deferasirox inhibits the reaction [CDK9 protein binds to CCNT1 protein] CTD PMID:17631934 NCBI chr 7:129,687,146...129,718,082
Ensembl chr 7:129,691,209...129,717,871 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity ISO deferasirox results in decreased activity of CDK2 protein CTD PMID:17631934 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 multiple interactions ISO deferasirox inhibits the reaction [CDK9 protein binds to CCNT1 protein] CTD PMID:17631934 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410 		JBrowse link
G Clu clusterin increases expression EXP deferasirox results in increased expression of CLU protein CTD PMID:21439361 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO
EXP		 deferasirox results in increased expression of HAVCR1 protein CTD PMID:21439361 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO
EXP		 deferasirox results in increased expression of LCN2 protein CTD PMID:21439361 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Polr2a RNA polymerase II subunit A decreases phosphorylation ISO deferasirox results in decreased phosphorylation of POLR2A protein CTD PMID:17631934 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455 		JBrowse link
triazophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO triazophos metabolite results in decreased activity of ACHE protein; triazophos results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression EXP triazophos results in decreased expression of BDNF mRNA; triazophos results in decreased expression of BDNF protein CTD PMID:23949197 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO triazophos metabolite affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19818
    chemical entity 19816
      atom 19816
        nonmetal atom 19749
          nitrogen atom 18922
            nitrogen molecular entity 18922
              organonitrogen compound 18757
                organonitrogen heterocyclic compound 18027
                  azole 13633
                    triazoles 6128
                      1-phenyl-1H-1,2,4-triazole 11
                        1-phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one 0
                        1-phenyl-1H-1,2,4-triazol-3-ol + 3
                        2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol + 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19818
    subatomic particle 19816
      composite particle 19816
        hadron 19816
          baryon 19816
            nucleon 19816
              atomic nucleus 19816
                atom 19816
                  main group element atom 19761
                    p-block element atom 19761
                      carbon group element atom 19703
                        carbon atom 19698
                          organic molecular entity 19698
                            organic molecule 19656
                              organic cyclic compound 19461
                                organic heterocyclic compound 18817
                                  heteroarene 16910
                                    monocyclic heteroarene 14267
                                      azole 13633
                                        triazoles 6128
                                          1-phenyl-1H-1,2,4-triazole 11
                                            1-phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one 0
                                            1-phenyl-1H-1,2,4-triazol-3-ol + 3
                                            2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol + 8
paths to the root