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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-phenyl-1H-1,2,4-triazole
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Accession:CHEBI:38967 term browser browse the term
Definition:A triazole that has formula C8H7N3.
Synonyms:related_synonym: Formula=C8H7N3;   InChI=1S/C8H7N3/c1-2-4-8(5-3-1)11-7-9-6-10-11/h1-7H;   InChIKey=CGRLXLHYYDSTKR-UHFFFAOYSA-N;   SMILES=c1ccc(cc1)-n1cncn1
 xref: Beilstein:116495;   CAS:13423-60-4



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deferasirox term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression
increases activity
ISO deferasirox results in increased expression of CASP3 protein
deferasirox results in increased activity of CASP3 protein
CTD PMID:21439361 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Ccnt1 cyclin T1 multiple interactions ISO deferasirox inhibits the reaction [CDK9 protein binds to CCNT1 protein] CTD PMID:17631934 NCBI chr 7:129,687,146...129,718,082
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases activity ISO deferasirox results in decreased activity of CDK2 protein CTD PMID:17631934 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdk9 cyclin-dependent kinase 9 multiple interactions ISO deferasirox inhibits the reaction [CDK9 protein binds to CCNT1 protein] CTD PMID:17631934 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Clu clusterin increases expression EXP deferasirox results in increased expression of CLU protein CTD PMID:21439361 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO
EXP
deferasirox results in increased expression of HAVCR1 protein CTD PMID:21439361 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO
EXP
deferasirox results in increased expression of LCN2 protein CTD PMID:21439361 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Polr2a RNA polymerase II subunit A decreases phosphorylation ISO deferasirox results in decreased phosphorylation of POLR2A protein CTD PMID:17631934 NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
JBrowse link
triazophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO triazophos metabolite results in decreased activity of ACHE protein; triazophos results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression EXP triazophos results in decreased expression of BDNF mRNA; triazophos results in decreased expression of BDNF protein CTD PMID:23949197 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20059
    chemical entity 20058
      atom 20056
        nonmetal atom 19944
          nitrogen atom 18922
            nitrogen molecular entity 18922
              organonitrogen compound 18699
                organonitrogen heterocyclic compound 17741
                  azole 12823
                    triazoles 3701
                      1-phenyl-1H-1,2,4-triazole 10
                        1-phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one 0
                        1-phenyl-1H-1,2,4-triazol-3-ol + 2
                        2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol + 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 20059
    subatomic particle 20056
      composite particle 20056
        hadron 20056
          baryon 20056
            nucleon 20056
              atomic nucleus 20056
                atom 20056
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19873
                          organic molecular entity 19873
                            organic molecule 19819
                              organic cyclic compound 19581
                                organic heterocyclic compound 18804
                                  heteroarene 16601
                                    monocyclic heteroarene 13600
                                      azole 12823
                                        triazoles 3701
                                          1-phenyl-1H-1,2,4-triazole 10
                                            1-phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one 0
                                            1-phenyl-1H-1,2,4-triazol-3-ol + 2
                                            2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol + 8
paths to the root