CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-phenyl-1H-1,2,4-triazole
Accession: CHEBI:38967
browse the term
Definition: A triazole that has formula C8H7N3.
Synonyms: related_synonym: Formula=C8H7N3; InChI=1S/C8H7N3/c1-2-4-8(5-3-1)11-7-9-6-10-11/h1-7H; InChIKey=CGRLXLHYYDSTKR-UHFFFAOYSA-N; SMILES=c1ccc(cc1)-n1cncn1
xref: Beilstein:116495; CAS:13423-60-4
G
Casp3
caspase 3
increases expression increases activity
ISO
deferasirox results in increased expression of CASP3 protein deferasirox results in increased activity of CASP3 protein
CTD
PMID:21439361
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Ccnt1
cyclin T1
multiple interactions
ISO
deferasirox inhibits the reaction [CDK9 protein binds to CCNT1 protein]
CTD
PMID:17631934
NCBI chr 7:129,687,146...129,718,082
Ensembl chr 7:129,691,209...129,717,871
G
Cdk2
cyclin dependent kinase 2
decreases activity
ISO
deferasirox results in decreased activity of CDK2 protein
CTD
PMID:17631934
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
G
Cdk9
cyclin-dependent kinase 9
multiple interactions
ISO
deferasirox inhibits the reaction [CDK9 protein binds to CCNT1 protein]
CTD
PMID:17631934
NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
G
Clu
clusterin
increases expression
EXP
deferasirox results in increased expression of CLU protein
CTD
PMID:21439361
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
G
Havcr1
hepatitis A virus cellular receptor 1
increases expression
ISO EXP
deferasirox results in increased expression of HAVCR1 protein
CTD
PMID:21439361
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
G
Lcn2
lipocalin 2
increases expression
ISO EXP
deferasirox results in increased expression of LCN2 protein
CTD
PMID:21439361
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
G
Polr2a
RNA polymerase II subunit A
decreases phosphorylation
ISO
deferasirox results in decreased phosphorylation of POLR2A protein
CTD
PMID:17631934
NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
G
Ache
acetylcholinesterase
decreases activity
ISO
triazophos metabolite results in decreased activity of ACHE protein; triazophos results in decreased activity of ACHE protein
CTD
PMID:33844597
NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
G
Bdnf
brain-derived neurotrophic factor
decreases expression
EXP
triazophos results in decreased expression of BDNF mRNA; triazophos results in decreased expression of BDNF protein
CTD
PMID:23949197
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
G
Tp53
tumor protein p53
affects activity
ISO
triazophos metabolite affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19818
chemical entity
19816
atom
19816
nonmetal atom
19749
nitrogen atom
18922
nitrogen molecular entity
18922
organonitrogen compound
18757
organonitrogen heterocyclic compound
18027
azole
13633
triazoles
6128
1-phenyl-1H-1,2,4-triazole
11
1-phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one
0
1-phenyl-1H-1,2,4-triazol-3-ol +
3
2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol +
8
Path 2
CHEBI ontology
19818
subatomic particle
19816
composite particle
19816
hadron
19816
baryon
19816
nucleon
19816
atomic nucleus
19816
atom
19816
main group element atom
19761
p-block element atom
19761
carbon group element atom
19703
carbon atom
19698
organic molecular entity
19698
organic molecule
19656
organic cyclic compound
19461
organic heterocyclic compound
18817
heteroarene
16910
monocyclic heteroarene
14267
azole
13633
triazoles
6128
1-phenyl-1H-1,2,4-triazole
11
1-phenyl-1,2-dihydro-3H-1,2,4-triazol-3-one
0
1-phenyl-1H-1,2,4-triazol-3-ol +
3
2,2'-(1-phenyl-1H-1,2,4-triazole-3,5-diyl)diphenol +
8