Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diphenyl sulfide
go back to main search page
Accession:CHEBI:38959 term browser browse the term
Definition:An aryl sulfide that consists of two phenyl groups connected by a sulphur atom.
Synonyms:exact_synonym: 1,1'-sulfanediyldibenzene
 related_synonym: (Phenylsulfanyl)benzene;   1,1'-Thiobis(benzene);   Diphenyl monosulfide;   Diphenyl sulphide;   Diphenyl thioether;   Diphenylmercaptan;   Diphenylthiamethane;   Formula=C12H10S;   InChI=1S/C12H10S/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10H;   InChIKey=LTYMSROWYAPPGB-UHFFFAOYSA-N;   Phenyl sulfide;   Phenylthiobenzene;   SMILES=S(c1ccccc1)c1ccccc1
 xref: Beilstein:1907932;   CAS:139-66-2;   PMID:11408364;   PMID:19274297;   Reaxys:1907932



show annotations for term's descendants           Sort by:
 
4,4'-thiodiphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding EXP bis(4-oxyphenyl)sulfide binds to AR protein CTD PMID:31836225 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Esr1 estrogen receptor 1 increases expression
multiple interactions
affects binding
ISO 4,4'-thiodiphenol results in increased expression of ESR1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased expression of ESR1 protein]; fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased expression of ESR1 protein]
bis(4-oxyphenyl)sulfide binds to ESR1 protein
CTD PMID:27880919 PMID:31836225 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects binding ISO bis(4-oxyphenyl)sulfide binds to ESR2 protein CTD PMID:31836225 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions
increases expression
ISO 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased expression of GPER1 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased expression of GPER1 protein] CTD PMID:27880919 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO 4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; wortmannin inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]
CTD PMID:27880919 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO 4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; Wortmannin inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]
CTD PMID:27880919 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
temephos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP Temefos results in decreased activity of ACHE protein CTD PMID:34382084 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Temefos results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Temefos inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19730
    chemical entity 19728
      atom 19728
        nonmetal atom 19668
          sulfur atom 17381
            sulfur molecular entity 17381
              organosulfur compound 16870
                organic sulfide 10091
                  aryl sulfide 8325
                    diphenyl sulfide 9
                      4,4'-thiodiphenol + 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19730
    subatomic particle 19728
      composite particle 19728
        hadron 19728
          baryon 19728
            nucleon 19728
              atomic nucleus 19728
                atom 19728
                  main group element atom 19676
                    p-block element atom 19676
                      carbon group element atom 19620
                        carbon atom 19616
                          organic molecular entity 19616
                            heteroorganic entity 19369
                              organochalcogen compound 19160
                                organosulfur compound 16870
                                  organic sulfide 10091
                                    aryl sulfide 8325
                                      diphenyl sulfide 9
                                        4,4'-thiodiphenol + 9
paths to the root