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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diphenyl sulfide
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Accession:CHEBI:38959 term browser browse the term
Definition:An aryl sulfide that consists of two phenyl groups connected by a sulphur atom.
Synonyms:exact_synonym: 1,1'-sulfanediyldibenzene
 related_synonym: (Phenylsulfanyl)benzene;   1,1'-Thiobis(benzene);   Diphenyl monosulfide;   Diphenyl sulphide;   Diphenyl thioether;   Diphenylmercaptan;   Diphenylthiamethane;   Formula=C12H10S;   InChI=1S/C12H10S/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10H;   InChIKey=LTYMSROWYAPPGB-UHFFFAOYSA-N;   Phenyl sulfide;   Phenylthiobenzene;   SMILES=S(c1ccccc1)c1ccccc1
 xref: Beilstein:1907932;   CAS:139-66-2;   PMID:11408364;   PMID:19274297;   Reaxys:1907932


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4,4'-thiodiphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 increases expression
multiple interactions
ISO 4,4'-thiodiphenol results in increased expression of ESR1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased expression of ESR1 protein]; fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased expression of ESR1 protein]
CTD PMID:27880919 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions
increases expression
ISO 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased expression of GPER1 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased expression of GPER1 protein] CTD PMID:27880919 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO 4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]; wortmannin inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]
CTD PMID:27880919 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO 4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; Fulvestrant inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]; Wortmannin inhibits the reaction [4,4'-thiodiphenol results in increased phosphorylation of MAPK3 protein]
CTD PMID:27880919 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
temephos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Temefos results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Temefos inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      atom 19782
        nonmetal atom 19657
          sulfur atom 16255
            sulfur molecular entity 16255
              organosulfur compound 15188
                organic sulfide 8132
                  aryl sulfide 7472
                    diphenyl sulfide 6
                      4,4'-thiodiphenol + 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            heteroorganic entity 19147
                              organochalcogen compound 18855
                                organosulfur compound 15188
                                  organic sulfide 8132
                                    aryl sulfide 7472
                                      diphenyl sulfide 6
                                        4,4'-thiodiphenol + 6
paths to the root

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