CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: intravenous anaesthetic
Accession: CHEBI:38877
browse the term
Synonyms: related_synonym: i.v.-Anaesthetika; i.v.-Anaesthetikum; intravenous anesthetics
G
Akr1c1
aldo-keto reductase family 1, member C1
increases reduction affects metabolic processing
ISO
AKR1C1 protein results in increased reduction of Pregnanolone AKR1C1 protein affects the metabolism of Pregnanolone
CTD
PMID:11995921 PMID:12604236
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
G
Akr1c2
aldo-keto reductase family 1, member C2
increases reduction affects metabolic processing
ISO
AKR1C2 protein results in increased reduction of Pregnanolone AKR1C2 protein affects the metabolism of Pregnanolone
CTD
PMID:11995921 PMID:12604236
NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
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Akr1c3
aldo-keto reductase family 1, member C3
increases chemical synthesis
ISO
AKR1C3 protein results in increased chemical synthesis of Pregnanolone
CTD
PMID:25463305
NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
G
Crh
corticotropin releasing hormone
affects expression multiple interactions
EXP
Pregnanolone affects the expression of CRH mRNA Pregnanolone inhibits the reaction [Methoxamine results in increased secretion of CRH protein]
CTD
PMID:7816204
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
increases hydroxylation
ISO
CYP17A1 protein results in increased hydroxylation of Pregnanolone analog
CTD
PMID:14522586
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Egr2
early growth response 2
increases expression
EXP
Pregnanolone results in increased expression of EGR2 mRNA; Pregnanolone results in increased expression of EGR2 protein
CTD
PMID:17478888
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO
Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]; Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form]
CTD
PMID:29038840
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
G
Gabra2
gamma-aminobutyric acid type A receptor subunit alpha 2
multiple interactions
ISO
Pregnanolone results in increased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]
CTD
PMID:29038840
NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944
G
Gabra4
gamma-aminobutyric acid type A receptor subunit alpha 4
increases expression multiple interactions
EXP ISO
Pregnanolone deficiency results in increased expression of GABRA4 mRNA; Pregnanolone deficiency results in increased expression of GABRA4 protein Pregnanolone results in increased activity of [GABRA4 protein binds to GABRB3 binds to GABRD protein]
CTD
PMID:9651210 PMID:29038840
NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
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Gabra6
gamma-aminobutyric acid type A receptor subunit alpha6
increases response to substance multiple interactions
ISO
GABRA6 protein results in increased susceptibility to Pregnanolone Pregnanolone results in increased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]
CTD
PMID:9281599 PMID:29038840
NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769
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Gabrb1
gamma-aminobutyric acid type A receptor subunit beta1
multiple interactions
ISO
Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]
CTD
PMID:29038840
NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
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Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
multiple interactions
ISO
Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]
CTD
PMID:29038840
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
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Gabrb3
gamma-aminobutyric acid type A receptor subunit beta 3
multiple interactions
ISO
Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Pregnanolone results in increased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Pregnanolone results in increased activity of [GABRA4 protein binds to GABRB3 binds to GABRD protein]; Pregnanolone results in increased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]
CTD
PMID:29038840
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
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Gabrd
gamma-aminobutyric acid type A receptor subunit delta
decreases expression multiple interactions
EXP ISO
Pregnanolone results in decreased expression of GABRD protein Pregnanolone results in increased activity of [GABRA4 protein binds to GABRB3 binds to GABRD protein]
CTD
PMID:16914187 PMID:29038840
NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411
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Gabre
gamma-aminobutyric acid type A receptor subunit epsilon
decreases response to substance
EXP
GABRE protein results in decreased susceptibility to Pregnanolone
CTD
PMID:9039914
NCBI chr X:150,060,035...150,078,773
Ensembl chr X:150,060,040...150,078,693
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Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO
Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]; Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Pregnanolone results in increased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Pregnanolone results in increased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Pregnanolone results in increased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]
CTD
PMID:29038840
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
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Gsk3b
glycogen synthase kinase 3 beta
decreases expression
EXP
Pregnanolone results in decreased expression of GSK3B protein
CTD
PMID:17443805
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Hsd17b10
hydroxysteroid (17-beta) dehydrogenase 10
multiple interactions
ISO
[Pregnanolone co-treated with NAD] binds to HSD17B10 protein
CTD
PMID:25526675
NCBI chr X:21,089,142...21,091,603
Ensembl chr X:21,089,122...21,109,488
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Il1b
interleukin 1 beta
decreases response to substance
ISO
Pregnanolone results in decreased susceptibility to IL1B protein
CTD
PMID:19458216
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Mag
myelin-associated glycoprotein
increases expression
EXP
Pregnanolone results in increased expression of MAG mRNA
CTD
PMID:16787508
NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
Pregnanolone results in decreased phosphorylation of and results in decreased activity of MAPK1 protein
CTD
PMID:16581232
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapt
microtubule-associated protein tau
increases phosphorylation decreases expression
EXP
Pregnanolone results in increased phosphorylation of MAPT protein Pregnanolone results in decreased expression of MAPT protein
CTD
PMID:17443805
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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Mpz
myelin protein zero
increases expression
EXP
Pregnanolone results in increased expression of MPZ mRNA
CTD
PMID:16787508
NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
multiple interactions increases activity
ISO
Pregnanolone metabolite inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] Pregnanolone metabolite results in increased activity of NR1H4 protein
CTD
PMID:22961653
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
multiple interactions
ISO
Pregnanolone analog inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]; Pregnanolone inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein]
CTD
PMID:16581232
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Penk
proenkephalin
increases expression
EXP
Pregnanolone results in increased expression of PENK mRNA
CTD
PMID:19458216
NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
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Pmp22
peripheral myelin protein 22
increases expression
EXP
Pregnanolone results in increased expression of PMP22 mRNA
CTD
PMID:16787508
NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
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Prkca
protein kinase C, alpha
decreases expression
ISO
Pregnanolone results in decreased expression of PRKCA protein
CTD
PMID:16581232
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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Slc1a1
solute carrier family 1 member 1
multiple interactions
EXP
Pregnanolone results in increased localization of and results in increased activity of SLC1A1 protein
CTD
PMID:21688266
NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
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Srd5a1
steroid 5 alpha-reductase 1
increases chemical synthesis
ISO
SRD5A1 protein results in increased chemical synthesis of Pregnanolone
CTD
PMID:25463305
NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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Cyb5a
cytochrome b5 type A
multiple interactions
ISO
CYB5A protein promotes the reaction [CYP3A4 protein affects the metabolism of Alfentanil]; CYB5A protein promotes the reaction [CYP3A5 protein affects the metabolism of Alfentanil]
CTD
PMID:15557344
NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
affects metabolic processing multiple interactions
ISO
CYP3A4 protein affects the metabolism of Alfentanil CYB5A protein promotes the reaction [CYP3A4 protein affects the metabolism of Alfentanil]
CTD
PMID:15557344 PMID:15731592
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
multiple interactions affects metabolic processing
ISO
CYB5A protein promotes the reaction [CYP3A5 protein affects the metabolism of Alfentanil]; Ketoconazole inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil]; Troleandomycin inhibits the reaction [CYP3A5 protein affects the metabolism of Alfentanil]
CTD
PMID:15557344 PMID:15731592 PMID:17554244
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Htr3a
5-hydroxytryptamine receptor 3A
affects activity
ISO
Alfentanil affects the activity of HTR3A protein
CTD
PMID:18635474
NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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Alb
albumin
multiple interactions
ISO
Etomidate promotes the reaction [ALB protein modified form results in increased chemical synthesis of Superoxides]; Etomidate promotes the reaction [ALB protein modified form results in increased cleavage of and results in increased activity of CASP3 protein]
CTD
PMID:25421967
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Cacna1i
calcium voltage-gated channel subunit alpha1 I
affects response to substance
EXP
CACNA1I protein affects the susceptibility to Etomidate
CTD
PMID:15644869
NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
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Casp3
caspase 3
multiple interactions
ISO
Etomidate promotes the reaction [ALB protein modified form results in increased cleavage of and results in increased activity of CASP3 protein]
CTD
PMID:25421967
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO EXP
Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Etomidate results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD
PMID:10049148 PMID:12939268
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
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Gabra5
gamma-aminobutyric acid type A receptor subunit alpha 5
multiple interactions affects response to substance
ISO
Etomidate binds to and results in increased activity of GABRA5 protein GABRA5 protein affects the susceptibility to Etomidate
CTD
PMID:16597725
NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917
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Gabrb1
gamma-aminobutyric acid type A receptor subunit beta1
multiple interactions
ISO
Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]
CTD
PMID:10049148
NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
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Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
affects response to substance multiple interactions
ISO EXP
GABRB2 protein affects the susceptibility to Etomidate Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Etomidate results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD
PMID:12490572 PMID:12939268
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
G
Gabrb3
gamma-aminobutyric acid type A receptor subunit beta 3
increases response to substance multiple interactions
ISO
GABRB3 protein results in increased susceptibility to Etomidate Etomidate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]
CTD
PMID:9523823 PMID:21111751
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
G
Gabre
gamma-aminobutyric acid type A receptor subunit epsilon
multiple interactions
ISO
Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]
CTD
PMID:10049148
NCBI chr X:150,060,035...150,078,773
Ensembl chr X:150,060,040...150,078,693
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO EXP
Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]] Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Etomidate results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD
PMID:10049148 PMID:12939268
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
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Stx1a
syntaxin 1A
affects localization
EXP
Etomidate affects the localization of STX1A protein
CTD
PMID:29320738
NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
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Abcb1a
ATP binding cassette subfamily B member 1A
increases transport multiple interactions increases response to substance
ISO EXP
ABCB1 protein results in increased transport of Fentanyl tariquidar inhibits the reaction [ABCB1 protein results in increased transport of Fentanyl] ABCB1 protein results in increased susceptibility to Fentanyl
CTD
PMID:29669042
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Arrb2
arrestin, beta 2
affects localization multiple interactions
ISO EXP
Fentanyl affects the localization of ARRB2 protein [Fentanyl binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein
CTD
PMID:27030709 PMID:35477798
NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
G
Calca
calcitonin-related polypeptide alpha
multiple interactions
EXP
Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Naloxone inhibits the reaction [Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]]
CTD
PMID:27030709
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
G
Crh
corticotropin releasing hormone
affects expression
EXP
Fentanyl affects the expression of CRH mRNA
CTD
PMID:18819432
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases activity
ISO
Fentanyl results in increased activity of CYP2B6 protein
CTD
PMID:35914676
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases metabolic processing
ISO
CYP3A4 protein results in increased metabolism of Fentanyl
CTD
PMID:11811955
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
EXP
Fentanyl results in increased expression of FOS protein
CTD
PMID:7970238
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Gast
gastrin
multiple interactions
EXP
[fluanisone co-treated with Fentanyl co-treated with Midazolam] inhibits the reaction [GAST protein results in increased secretion of Histamine]
CTD
PMID:10864877
NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496
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Il2
interleukin 2
decreases expression
ISO
Fentanyl results in decreased expression of IL2 mRNA
CTD
PMID:23965172
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il4
interleukin 4
increases expression
ISO
Fentanyl results in increased expression of IL4 mRNA
CTD
PMID:23965172
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Kcnh2
potassium voltage-gated channel subfamily H member 2
decreases activity
ISO
Fentanyl results in decreased activity of KCNH2 protein
CTD
PMID:28551711
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
G
Mapk1
mitogen activated protein kinase 1
increases phosphorylation
ISO
Fentanyl results in increased phosphorylation of MAPK1 protein
CTD
PMID:23965172
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
increases phosphorylation
ISO
Fentanyl results in increased phosphorylation of MAPK3 protein
CTD
PMID:23965172
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Nfkbia
NFKB inhibitor alpha
increases expression
ISO
Fentanyl results in increased expression of NFKBIA protein
CTD
PMID:22258905
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Oprd1
opioid receptor, delta 1
affects binding
EXP
Fentanyl binds to OPRD1 protein
CTD
PMID:35477798
NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
G
Oprk1
opioid receptor, kappa 1
affects binding
EXP
Fentanyl binds to OPRK1 protein
CTD
PMID:35477798
NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
G
Oprm1
opioid receptor, mu 1
increases phosphorylation multiple interactions
ISO EXP
Fentanyl results in increased phosphorylation of OPRM1 protein [Fentanyl binds to and results in increased activity of OPRM1 protein] which results in increased activity of ARRB2 protein; Fentanyl binds to and results in increased activity of OPRM1 protein
CTD
PMID:17240843 PMID:21957251 PMID:23300227 PMID:35477798
NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
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Pdyn
prodynorphin
increases expression
EXP
Fentanyl results in increased expression of PDYN protein
CTD
PMID:19200067
NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
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Pld2
phospholipase D2
increases activity
ISO
Fentanyl results in increased activity of PLD2 protein
CTD
PMID:23965172
NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
G
Pomc
proopiomelanocortin
decreases expression multiple interactions
ISO
Fentanyl results in decreased expression of POMC protein alternative form [Fentanyl co-treated with Morphine] results in decreased expression of POMC protein alternative form
CTD
PMID:20084599
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
G
Ren
renin
multiple interactions
ISO
[Fentanyl co-treated with Isoflurane] results in decreased expression of REN protein
CTD
PMID:3284271
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Abca1
ATP binding cassette subfamily A member 1
increases expression
EXP
Ketamine results in increased expression of ABCA1 mRNA
CTD
PMID:20080153
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
G
Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions
ISO
ABCB1A protein affects the susceptibility to [Pentobarbital co-treated with Ketamine]
CTD
PMID:17959987
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
G
Abcg1
ATP binding cassette subfamily G member 1
increases expression
EXP
Ketamine results in increased expression of ABCG1 mRNA
CTD
PMID:20080153
NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
G
Abhd16a
abhydrolase domain containing 16A, phospholipase
increases expression
EXP
Ketamine results in increased expression of ABHD16A mRNA
CTD
PMID:20080153
NCBI chr20:3,719,089...3,733,952
Ensembl chr20:3,719,091...3,733,927
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Abhd5
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
decreases expression
EXP
Ketamine results in decreased expression of ABHD5 mRNA
CTD
PMID:20080153
NCBI chr 8:122,000,241...122,026,447
Ensembl chr 8:122,000,389...122,026,447
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Acat2
acetyl-CoA acetyltransferase 2
decreases expression
EXP
Ketamine results in decreased expression of ACAT2 mRNA
CTD
PMID:20080153
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acbd3
acyl-CoA binding domain containing 3
decreases expression
EXP
Ketamine results in decreased expression of ACBD3 mRNA
CTD
PMID:20080153
NCBI chr13:92,455,813...92,484,556
Ensembl chr13:92,455,655...92,483,380
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Acbd5
acyl-CoA binding domain containing 5
decreases expression
EXP
Ketamine results in decreased expression of ACBD5 mRNA
CTD
PMID:20080153
NCBI chr17:85,206,178...85,248,909
Ensembl chr17:85,206,303...85,248,215
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Ace
angiotensin I converting enzyme
increases expression
EXP
Ketamine results in increased expression of ACE mRNA
CTD
PMID:20080153
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Acp6
acid phosphatase 6, lysophosphatidic
decreases expression
EXP
Ketamine results in decreased expression of ACP6 mRNA
CTD
PMID:20080153
NCBI chr 2:184,711,975...184,733,067
Ensembl chr 2:184,711,619...184,733,017
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Acr
acrosin
increases expression
EXP
Ketamine results in increased expression of ACR mRNA
CTD
PMID:20080153
NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474
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Acsbg1
acyl-CoA synthetase bubblegum family member 1
increases expression
EXP
Ketamine results in increased expression of ACSBG1 mRNA
CTD
PMID:20080153
NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391
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Acta2
actin alpha 2, smooth muscle
multiple interactions increases expression
ISO
2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in increased expression of ACTA2 protein] Ketamine results in increased expression of ACTA2 mRNA; Ketamine results in increased expression of ACTA2 protein
CTD
PMID:28331066
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actg2
actin gamma 2, smooth muscle
decreases expression
EXP
Ketamine results in decreased expression of ACTG2 mRNA
CTD
PMID:20080153
NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
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Acvr1c
activin A receptor type 1C
decreases expression
EXP
Ketamine results in decreased expression of ACVR1C mRNA
CTD
PMID:20080153
NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
G
Adap2
ArfGAP with dual PH domains 2
increases expression
EXP
Ketamine results in increased expression of ADAP2 mRNA
CTD
PMID:20080153
NCBI chr10:65,138,006...65,166,147
Ensembl chr10:65,138,020...65,165,604
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Adck2
aarF domain containing kinase 2
decreases expression
EXP
Ketamine results in decreased expression of ADCK2 mRNA
CTD
PMID:20080153
NCBI chr 4:68,348,853...68,362,725
Ensembl chr 4:68,348,864...68,374,608
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Adcy8
adenylate cyclase 8
decreases expression
EXP
Ketamine results in decreased expression of ADCY8 mRNA
CTD
PMID:20080153
NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911
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Adcy9
adenylate cyclase 9
increases expression
EXP
Ketamine results in increased expression of ADCY9 mRNA
CTD
PMID:20080153
NCBI chr10:11,138,966...11,262,067
Ensembl chr10:11,139,446...11,262,066
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Adcyap1
adenylate cyclase activating polypeptide 1
decreases expression
EXP
Ketamine results in decreased expression of ADCYAP1 mRNA
CTD
PMID:20080153
NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
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Add2
adducin 2
decreases expression
EXP
Ketamine results in decreased expression of ADD2 mRNA
CTD
PMID:20080153
NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505
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Adgrb2
adhesion G protein-coupled receptor B2
increases expression
EXP
Ketamine results in increased expression of ADGRB2 mRNA
CTD
PMID:20080153
NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540
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Afp
alpha-fetoprotein
increases expression
EXP
Ketamine results in increased expression of AFP mRNA
CTD
PMID:20080153
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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Agt
angiotensinogen
decreases expression increases expression
ISO EXP
Ketamine results in decreased expression of AGT protein Ketamine results in increased expression of AGT mRNA
CTD
PMID:6349867 PMID:20080153
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
G
Agtrap
angiotensin II receptor-associated protein
increases expression
EXP
Ketamine results in increased expression of AGTRAP mRNA
CTD
PMID:20080153
NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036
G
Ahr
aryl hydrocarbon receptor
decreases expression
EXP
Ketamine results in decreased expression of AHR mRNA
CTD
PMID:20080153
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Aif1
allograft inflammatory factor 1
decreases expression multiple interactions
EXP
Ketamine results in decreased expression of AIF1 mRNA Cannabidiol inhibits the reaction [Ketamine results in decreased expression of AIF1 mRNA]
CTD
PMID:31823199
NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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Akap9
A-kinase anchoring protein 9
decreases expression
EXP
Ketamine results in decreased expression of AKAP9 mRNA
CTD
PMID:20080153
NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
G
Alb
albumin
increases expression
EXP
Ketamine results in increased expression of ALB mRNA
CTD
PMID:20080153
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Aldh18a1
aldehyde dehydrogenase 18 family, member A1
decreases expression
EXP
Ketamine results in decreased expression of ALDH18A1 mRNA
CTD
PMID:20080153
NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890
G
Aldoc
aldolase, fructose-bisphosphate C
increases expression
EXP
Ketamine results in increased expression of ALDOC mRNA
CTD
PMID:20080153
NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
G
Alms1
ALMS1, centrosome and basal body associated protein
decreases expression
EXP
Ketamine results in decreased expression of ALMS1 mRNA
CTD
PMID:20080153
NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
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Amigo2
adhesion molecule with Ig like domain 2
decreases expression
EXP
Ketamine results in decreased expression of AMIGO2 mRNA
CTD
PMID:20080153
NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
G
Anapc1
anaphase promoting complex subunit 1
increases expression
EXP
Ketamine results in increased expression of ANAPC1 mRNA
CTD
PMID:20080153
NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273
G
Angptl4
angiopoietin-like 4
increases expression
EXP
Ketamine results in increased expression of ANGPTL4 mRNA
CTD
PMID:20080153
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
G
Ankrd42
ankyrin repeat domain 42
decreases expression
EXP
Ketamine results in decreased expression of ANKRD42 mRNA
CTD
PMID:20080153
NCBI chr 1:146,648,080...146,691,086
Ensembl chr 1:146,648,080...146,691,108
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Anxa11
annexin A11
increases expression
EXP
Ketamine results in increased expression of ANXA11 mRNA
CTD
PMID:20080153
NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797
G
Anxa3
annexin A3
decreases expression
EXP
Ketamine results in decreased expression of ANXA3 mRNA
CTD
PMID:20080153
NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
G
Anxa4
annexin A4
increases expression
EXP
Ketamine results in increased expression of ANXA4 mRNA
CTD
PMID:20080153
NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
G
Anxa5
annexin A5
decreases expression
EXP
Ketamine results in decreased expression of ANXA5 mRNA
CTD
PMID:20080153
NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
G
Ap2m1
adaptor related protein complex 2 subunit mu 1
multiple interactions
ISO
Ketamine inhibits the reaction [NTRK2 protein binds to AP2M1 protein]
CTD
PMID:31631060
NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
G
Ap3m1
adaptor related protein complex 3 subunit mu 1
decreases expression
EXP
Ketamine results in decreased expression of AP3M1 mRNA
CTD
PMID:20080153
NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844
G
Ap5m1
adaptor related protein complex 5 subunit mu 1
decreases expression
EXP
Ketamine results in decreased expression of AP5M1 mRNA
CTD
PMID:20080153
NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750
G
Apex2
apurinic/apyrimidinic endodeoxyribonuclease 2
decreases expression
EXP
Ketamine results in decreased expression of APEX2 mRNA
CTD
PMID:20080153
NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439
G
Aplf
aprataxin and PNKP like factor
decreases expression
EXP
Ketamine results in decreased expression of APLF mRNA
CTD
PMID:20080153
NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633
G
Apmap
adipocyte plasma membrane associated protein
increases expression
EXP
Ketamine results in increased expression of APMAP mRNA
CTD
PMID:20080153
NCBI chr 3:139,409,021...139,437,296
Ensembl chr 3:139,409,022...139,437,341
G
Apoe
apolipoprotein E
decreases response to substance increases expression
ISO EXP
APOE results in decreased susceptibility to Ketamine Ketamine results in increased expression of APOE mRNA
CTD
PMID:9778666 PMID:20080153
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
App
amyloid beta precursor protein
increases expression multiple interactions
ISO
Ketamine results in increased expression of APP mRNA [Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-40); [Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-42); Ketamine results in decreased expression of and results in increased cleavage of APP protein; Monensin inhibits the reaction [[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-40)]; Monensin inhibits the reaction [[Ketamine results in increased cleavage of APP protein] which results in increased abundance of amyloid beta-protein (1-42)] Ketamine results in decreased expression of and results in increased cleavage of APP protein; Monensin inhibits the reaction [Ketamine results in decreased expression of and results in increased cleavage of APP protein]
CTD
PMID:35378374
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Appbp2
amyloid beta precursor protein binding protein 2
decreases expression
EXP
Ketamine results in decreased expression of APPBP2 mRNA
CTD
PMID:20080153
NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
G
Arfgef1
ADP ribosylation factor guanine nucleotide exchange factor 1
decreases expression
EXP
Ketamine results in decreased expression of ARFGEF1 mRNA
CTD
PMID:20080153
NCBI chr 5:8,982,061...9,076,326
Ensembl chr 5:8,981,540...9,076,326
G
Arhgap5
Rho GTPase activating protein 5
decreases expression
EXP
Ketamine results in decreased expression of ARHGAP5 mRNA
CTD
PMID:20080153
NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660
G
Arih1
ariadne RBR E3 ubiquitin protein ligase 1
decreases expression
EXP
Ketamine results in decreased expression of ARIH1 mRNA
CTD
PMID:20080153
NCBI chr 8:59,777,378...59,879,762
Ensembl chr 8:59,777,379...59,880,245
G
Arl6
ADP-ribosylation factor like GTPase 6
decreases expression
EXP
Ketamine results in decreased expression of ARL6 mRNA
CTD
PMID:20080153
NCBI chr11:40,711,878...40,738,254
Ensembl chr11:40,712,022...40,737,937
G
Arl6ip6
ADP ribosylation factor like GTPase 6 interacting protein 6
decreases expression
EXP
Ketamine results in decreased expression of ARL6IP6 mRNA
CTD
PMID:20080153
NCBI chr 3:37,689,994...37,720,358
Ensembl chr 3:37,690,382...37,718,018
G
Armc10
armadillo repeat containing 10
decreases expression
EXP
Ketamine results in decreased expression of ARMC10 mRNA
CTD
PMID:20080153
NCBI chr 4:13,399,004...13,414,594
Ensembl chr 4:13,395,207...13,414,548
G
Art3
ADP-ribosyltransferase 3
increases expression
EXP
Ketamine results in increased expression of ART3 mRNA
CTD
PMID:20080153
NCBI chr14:15,637,230...15,719,442
Ensembl chr14:15,637,237...15,665,407
G
Ascl1
achaete-scute family bHLH transcription factor 1
decreases expression
EXP
Ketamine results in decreased expression of ASCL1 mRNA
CTD
PMID:20080153
NCBI chr 7:21,903,136...21,906,003
Ensembl chr 7:21,903,126...21,905,993
G
Asic4
acid sensing ion channel subunit family member 4
increases expression
EXP
Ketamine results in increased expression of ASIC4 mRNA
CTD
PMID:20080153
NCBI chr 9:76,941,532...76,962,900
Ensembl chr 9:76,941,532...76,962,900
G
Aspdh
aspartate dehydrogenase domain containing
increases expression
EXP
Ketamine results in increased expression of ASPDH mRNA
CTD
PMID:20080153
NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722
G
Atf4
activating transcription factor 4
increases expression
ISO
Ketamine results in increased expression of ATF4 mRNA
CTD
PMID:35728656
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
G
Atf6
activating transcription factor 6
increases expression
ISO
Ketamine results in increased expression of ATF6 mRNA
CTD
PMID:35728656
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
G
Atg12
autophagy related 12
increases expression
EXP
Ketamine results in increased expression of ATG12 mRNA
CTD
PMID:20080153
NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
G
Atp13a4
ATPase 13A4
increases expression
EXP
Ketamine results in increased expression of ATP13A4 mRNA
CTD
PMID:20080153
NCBI chr11:71,222,196...71,359,933
Ensembl chr11:71,226,161...71,359,933
G
Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
increases expression
EXP
Ketamine results in increased expression of ATP1A1 mRNA
CTD
PMID:20080153
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
G
Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
increases expression
EXP
Ketamine results in increased expression of ATP1A2 mRNA
CTD
PMID:20080153
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
G
Atp1a3
ATPase Na+/K+ transporting subunit alpha 3
increases expression
EXP
Ketamine results in increased expression of ATP1A3 mRNA
CTD
PMID:20080153
NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
G
Atp6v0a1
ATPase H+ transporting V0 subunit a1
increases expression
EXP
Ketamine results in increased expression of ATP6V0A1 mRNA
CTD
PMID:20080153
NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
G
Atp6v1c2
ATPase H+ transporting V1 subunit C2
increases expression
EXP
Ketamine results in increased expression of ATP6V1C2 mRNA
CTD
PMID:20080153
NCBI chr 6:40,080,545...40,144,199
Ensembl chr 6:40,080,547...40,120,028
G
Atp7a
ATPase copper transporting alpha
decreases expression
EXP
Ketamine results in decreased expression of ATP7A mRNA
CTD
PMID:20080153
NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
G
B4gat1
beta-1,4-glucuronyltransferase 1
increases expression
EXP
Ketamine results in increased expression of B4GAT1 mRNA
CTD
PMID:20080153
NCBI chr 1:202,343,268...202,345,490
Ensembl chr 1:202,343,240...202,346,065
G
Bace1
beta-secretase 1
increases expression multiple interactions
ISO
Ketamine results in increased expression of BACE1 protein Ketamine results in increased expression of and affects the localization of BACE1 protein; Monensin inhibits the reaction [Ketamine results in increased expression of and affects the localization of BACE1 protein]
CTD
PMID:35378374
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
G
Bag3
BAG cochaperone 3
increases expression
EXP
Ketamine results in increased expression of BAG3 mRNA
CTD
PMID:20080153
NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
G
Baiap2
BAR/IMD domain containing adaptor protein 2
increases expression
EXP
Ketamine results in increased expression of BAIAP2 mRNA
CTD
PMID:20080153
NCBI chr10:105,223,065...105,290,130
Ensembl chr10:105,223,090...105,290,134
G
Banp
Btg3 associated nuclear protein
decreases expression
EXP
Ketamine results in decreased expression of BANP mRNA
CTD
PMID:20080153
NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738
G
Bax
BCL2 associated X, apoptosis regulator
affects localization increases expression multiple interactions
ISO EXP
Ketamine affects the localization of BAX protein Ketamine results in increased expression of BAX mRNA; Ketamine results in increased expression of BAX protein Curcumin inhibits the reaction [Ketamine results in increased expression of BAX mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of BAX protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX protein]
CTD
PMID:18456338 PMID:19001360 PMID:25937004 PMID:33536391 PMID:36305173
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bckdha
branched chain keto acid dehydrogenase E1 subunit alpha
increases expression
EXP
Ketamine results in increased expression of BCKDHA mRNA
CTD
PMID:20080153
NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
G
Bcl2
BCL2, apoptosis regulator
multiple interactions decreases expression
EXP ISO
Curcumin affects the reaction [Ketamine results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Ketamine results in decreased expression of BCL2 mRNA]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 mRNA]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 protein] Ketamine results in decreased expression of BCL2 mRNA; Ketamine results in decreased expression of BCL2 protein LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]
CTD
PMID:33536391 PMID:36305173 PMID:36907275
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
G
Bclaf3
BCLAF1 and THRAP3 family member 3
decreases expression
EXP
Ketamine results in decreased expression of BCLAF3 mRNA
CTD
PMID:20080153
NCBI chr X:35,257,228...35,328,883
Ensembl chr X:35,263,576...35,328,816
G
Bcorl1
BCL6 co-repressor-like 1
decreases expression
EXP
Ketamine results in decreased expression of BCORL1 mRNA
CTD
PMID:20080153
NCBI chr X:127,516,504...127,584,529
Ensembl chr X:127,537,538...127,584,087
G
Bcs1l
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
decreases expression
EXP
Ketamine results in decreased expression of BCS1L mRNA
CTD
PMID:20080153
NCBI chr 9:76,164,925...76,168,940
Ensembl chr 9:76,164,932...76,168,938
G
Bdkrb1
bradykinin receptor B1
increases expression
ISO
Ketamine results in increased expression of BDKRB1 mRNA; Ketamine results in increased expression of BDKRB1 protein
CTD
PMID:27638051
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
G
Bdnf
brain-derived neurotrophic factor
multiple interactions increases expression
EXP ISO
Ketamine inhibits the reaction [Isoflurophate results in decreased expression of BDNF protein]; Ketamine inhibits the reaction [Pilocarpine results in increased expression of BDNF mRNA] Sirolimus inhibits the reaction [Ketamine results in increased expression of BDNF protein]
CTD
PMID:8635431 PMID:32592718 PMID:33022268
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
G
Becn1
beclin 1
increases expression
ISO
Ketamine results in increased expression of BECN1 protein
CTD
PMID:34487425
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
G
Bhlhe22
basic helix-loop-helix family, member e22
decreases expression
EXP
Ketamine results in decreased expression of BHLHE22 mRNA
CTD
PMID:20080153
NCBI chr 2:100,486,400...100,489,510
Ensembl chr 2:100,486,400...100,489,510
G
Bhlhe40
basic helix-loop-helix family, member e40
increases expression
EXP
Ketamine results in increased expression of BHLHE40 mRNA
CTD
PMID:20080153
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
G
Bhlhe41
basic helix-loop-helix family, member e41
increases expression
EXP
Ketamine results in increased expression of BHLHE41 mRNA
CTD
PMID:20080153
NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468
G
Bmi1
BMI1 proto-oncogene, polycomb ring finger
decreases expression
EXP
Ketamine results in decreased expression of BMI1 mRNA
CTD
PMID:20080153
NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690
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Bnip3
BCL2 interacting protein 3
decreases expression
EXP
Ketamine results in decreased expression of BNIP3 mRNA
CTD
PMID:20080153
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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Braf
B-Raf proto-oncogene, serine/threonine kinase
multiple interactions
ISO
Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of BRAF protein]
CTD
PMID:19540866
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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Brinp2
BMP/retinoic acid inducible neural specific 2
increases expression
EXP
Ketamine results in increased expression of BRINP2 mRNA
CTD
PMID:20080153
NCBI chr13:70,431,006...70,532,766
Ensembl chr13:70,431,010...70,531,810
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Btg1
BTG anti-proliferation factor 1
decreases expression
EXP
Ketamine results in decreased expression of BTG1 mRNA
CTD
PMID:20080153
NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
decreases expression
EXP
Ketamine results in decreased expression of BUB1B mRNA
CTD
PMID:20080153
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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C17h5orf24
similar to human chromosome 5 open reading frame 24
decreases expression
EXP
Ketamine results in decreased expression of C17H5ORF24 mRNA
CTD
PMID:20080153
NCBI chr17:8,923,041...8,932,958
Ensembl chr17:8,922,675...8,933,356
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C1qa
complement C1q A chain
increases expression
EXP
Ketamine results in increased expression of C1QA mRNA
CTD
PMID:20080153
NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
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C1qb
complement C1q B chain
increases expression
EXP
Ketamine results in increased expression of C1QB mRNA
CTD
PMID:20080153
NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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C1qc
complement C1q C chain
increases expression multiple interactions decreases expression
EXP
Ketamine results in increased expression of C1QC mRNA Cannabidiol inhibits the reaction [Ketamine results in decreased expression of C1QC mRNA]
CTD
PMID:20080153 PMID:31823199
NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
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C2
complement C2
increases expression
EXP
Ketamine results in increased expression of C2 mRNA
CTD
PMID:20080153
NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505
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C2cd2l
C2CD2-like
increases expression
EXP
Ketamine results in increased expression of C2CD2L mRNA
CTD
PMID:20080153
NCBI chr 8:44,648,074...44,658,856
Ensembl chr 8:44,648,079...44,658,340
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C2cd4b
C2 calcium-dependent domain containing 4B
increases expression
EXP
Ketamine results in increased expression of C2CD4B mRNA
CTD
PMID:20080153
NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
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C4bpb
complement component 4 binding protein, beta
increases expression
EXP
Ketamine results in increased expression of C4BPB mRNA
CTD
PMID:20080153
NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817
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Caap1
caspase activity and apoptosis inhibitor 1
decreases expression
EXP
Ketamine results in decreased expression of CAAP1 mRNA
CTD
PMID:20080153
NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
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Cabcoco1
ciliary associated calcium binding coiled-coil 1
increases expression
EXP
Ketamine results in increased expression of CABCOCO1 mRNA
CTD
PMID:20080153
NCBI chr20:20,058,492...20,167,973
Ensembl chr20:20,058,454...20,167,725
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Cabp7
calcium binding protein 7
increases expression
EXP
Ketamine results in increased expression of CABP7 mRNA
CTD
PMID:20080153
NCBI chr14:79,598,822...79,609,172
Ensembl chr14:79,598,827...79,609,240
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Cacng2
calcium voltage-gated channel auxiliary subunit gamma 2
increases expression
EXP
Ketamine results in increased expression of CACNG2 mRNA
CTD
PMID:20080153
NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
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Calb2
calbindin 2
increases expression
EXP
Ketamine results in increased expression of CALB2 mRNA
CTD
PMID:20080153
NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
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Camkk1
calcium/calmodulin-dependent protein kinase kinase 1
increases expression
EXP
Ketamine results in increased expression of CAMKK1 mRNA
CTD
PMID:20080153
NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498
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Cand2
cullin-associated and neddylation-dissociated 2 (putative)
decreases expression
EXP
Ketamine results in decreased expression of CAND2 mRNA
CTD
PMID:20080153
NCBI chr 4:148,835,050...148,864,039
Ensembl chr 4:148,835,053...148,863,153
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Cant1
calcium activated nucleotidase 1
increases expression
EXP
Ketamine results in increased expression of CANT1 mRNA
CTD
PMID:20080153
NCBI chr10:103,637,079...103,650,240
Ensembl chr10:103,531,504...103,650,109
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Car4
carbonic anhydrase 4
increases expression
EXP
Ketamine results in increased expression of CAR4 mRNA
CTD
PMID:20080153
NCBI chr10:69,827,945...69,836,501
Ensembl chr10:69,827,945...69,836,501
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Car7
carbonic anhydrase 7
increases expression
EXP
Ketamine results in increased expression of CAR7 mRNA
CTD
PMID:20080153
NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467
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Casp3
caspase 3
increases activity multiple interactions increases cleavage increases expression
ISO EXP
Ketamine results in increased activity of CASP3 protein LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein] Ketamine results in increased expression of CASP3 mRNA; Ketamine results in increased expression of CASP3 protein; Ketamine results in increased expression of CASP3 protein modified form Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 mRNA]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein modified form]; Curcumin inhibits the reaction [Ketamine results in increased expression of CASP3 protein]; TRPV4 protein affects the reaction [Ketamine results in increased cleavage of CASP3 protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of CASP3 mRNA]
CTD
PMID:17920787 PMID:19001360 PMID:25937004 PMID:33536391 PMID:36305173 PMID:36907275 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp6
caspase 6
increases activity
ISO
Ketamine results in increased activity of CASP6 protein
CTD
PMID:19001360
NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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Casp9
caspase 9
increases activity increases expression
ISO EXP
Ketamine results in increased activity of CASP9 protein Ketamine results in increased expression of CASP9 mRNA
CTD
PMID:19001360 PMID:20080153
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
decreases activity multiple interactions
EXP
Ketamine results in decreased activity of CAT protein TRPV4 protein affects the reaction [Ketamine results in decreased activity of CAT protein]
CTD
PMID:33536391
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cbr3
carbonyl reductase 3
decreases expression
EXP
Ketamine results in decreased expression of CBR3 mRNA
CTD
PMID:20080153
NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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Cbx1
chromobox 1
decreases expression
EXP
Ketamine results in decreased expression of CBX1 mRNA
CTD
PMID:20080153
NCBI chr10:81,770,307...81,789,981
Ensembl chr10:81,770,342...81,791,096
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Cbx7
chromobox 7
increases expression
EXP
Ketamine results in increased expression of CBX7 mRNA
CTD
PMID:20080153
NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973
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Ccdc115
coiled-coil domain containing 115
increases expression
EXP
Ketamine results in increased expression of CCDC115 mRNA
CTD
PMID:20080153
NCBI chr 9:36,650,384...36,654,348
Ensembl chr 9:36,649,271...36,653,946
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Ccdc50
coiled-coil domain containing 50
decreases expression
EXP
Ketamine results in decreased expression of CCDC50 mRNA
CTD
PMID:20080153
NCBI chr11:73,332,798...73,395,333
Ensembl chr11:73,334,248...73,395,150
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Ccdc85a
coiled-coil domain containing 85A
decreases expression
EXP
Ketamine results in decreased expression of CCDC85A mRNA
CTD
PMID:20080153
NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058
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Ccdc90b
coiled-coil domain containing 90B
decreases expression
EXP
Ketamine results in decreased expression of CCDC90B mRNA
CTD
PMID:20080153
NCBI chr 1:146,632,756...146,646,314
Ensembl chr 1:146,633,036...146,647,338
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Ccl5
C-C motif chemokine ligand 5
multiple interactions
ISO
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CCL5 protein]
CTD
PMID:22245128
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccna2
cyclin A2
decreases expression
EXP
Ketamine results in decreased expression of CCNA2 mRNA
CTD
PMID:20080153
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnd1
cyclin D1
decreases expression
EXP
Ketamine results in decreased expression of CCND1 mRNA
CTD
PMID:20080153
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccndbp1
cyclin D1 binding protein 1
decreases expression
EXP
Ketamine results in decreased expression of CCNDBP1 mRNA
CTD
PMID:20080153
NCBI chr 3:107,962,402...107,974,234
Ensembl chr 3:107,962,261...107,974,233
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Ccpg1
cell cycle progression 1
increases expression
EXP
Ketamine results in increased expression of CCPG1 mRNA
CTD
PMID:20080153
NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
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Ccr5
C-C motif chemokine receptor 5
increases expression
EXP
Ketamine results in increased expression of CCR5 mRNA
CTD
PMID:20080153
NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
G
Ccsap
centriole, cilia and spindle-associated protein
increases expression
EXP
Ketamine results in increased expression of CCSAP mRNA
CTD
PMID:20080153
NCBI chr19:51,824,954...51,843,469
Ensembl chr19:51,826,994...51,842,753
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Cd24
CD24 molecule
decreases expression
EXP
Ketamine results in decreased expression of CD24 mRNA
CTD
PMID:20080153
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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Cd38
CD38 molecule
increases expression
EXP
Ketamine results in increased expression of CD38 mRNA
CTD
PMID:20080153
NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
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Cd83
CD83 molecule
increases expression
EXP
Ketamine results in increased expression of CD83 mRNA
CTD
PMID:20080153
NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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Cdc42ep3
CDC42 effector protein 3
decreases expression
EXP
Ketamine results in decreased expression of CDC42EP3 mRNA
CTD
PMID:20080153
NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721
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Cdc6
cell division cycle 6
decreases expression
EXP
Ketamine results in decreased expression of CDC6 mRNA
CTD
PMID:20080153
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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Cdca7
cell division cycle associated 7
decreases expression
EXP
Ketamine results in decreased expression of CDCA7 mRNA
CTD
PMID:20080153
NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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Cdh1
cadherin 1
decreases expression multiple interactions
EXP ISO
Ketamine results in decreased expression of CDH1 protein Ketamine results in decreased expression of CDH1 mRNA; Ketamine results in decreased expression of CDH1 protein 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in decreased expression of CDH1 protein]
CTD
PMID:28331066
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdh11
cadherin 11
decreases expression
EXP
Ketamine results in decreased expression of CDH11 mRNA
CTD
PMID:20080153
NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
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Cdh7
cadherin 7
decreases expression
EXP
Ketamine results in decreased expression of CDH7 mRNA
CTD
PMID:20080153
NCBI chr13:26,672,058...26,821,571
Ensembl chr13:26,672,484...26,819,846
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Cdk1
cyclin-dependent kinase 1
decreases expression
EXP
Ketamine results in decreased expression of CDK1 mRNA
CTD
PMID:20080153
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Cdk14
cyclin-dependent kinase 14
decreases expression
EXP
Ketamine results in decreased expression of CDK14 mRNA
CTD
PMID:20080153
NCBI chr 4:28,666,416...29,258,865
Ensembl chr 4:28,666,843...29,258,861
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Cdnf
cerebral dopamine neurotrophic factor
affects expression
ISO
Ketamine affects the expression of CDNF mRNA
CTD
PMID:35728656
NCBI chr17:74,714,564...74,728,639
Ensembl chr17:74,713,564...74,728,639
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Cebpb
CCAAT/enhancer binding protein beta
increases expression
EXP
Ketamine results in increased expression of CEBPB mRNA
CTD
PMID:20080153
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Cenpc
centromere protein C
decreases expression
EXP
Ketamine results in decreased expression of CENPC1 mRNA
CTD
PMID:20080153
NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476
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Cep70
centrosomal protein 70
decreases expression
EXP
Ketamine results in decreased expression of CEP70 mRNA
CTD
PMID:20080153
NCBI chr 8:99,810,270...99,863,279
Ensembl chr 8:99,810,367...99,862,855
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Cfap126
cilia and flagella associated protein 126
increases expression
EXP
Ketamine results in increased expression of CFAP126 mRNA
CTD
PMID:20080153
NCBI chr13:83,526,657...83,542,552
Ensembl chr13:83,526,657...83,542,552
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Cfap410
cilia and flagella associated protein 410
increases expression
EXP
Ketamine results in increased expression of CFAP410 mRNA
CTD
PMID:20080153
NCBI chr20:10,687,863...10,694,736
Ensembl chr20:10,687,863...10,694,737
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Chi3l1
chitinase 3 like 1
increases expression
EXP
Ketamine results in increased expression of CHI3L1 mRNA
CTD
PMID:20080153
NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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Chordc1
cysteine and histidine rich domain containing 1
decreases expression
EXP
Ketamine results in decreased expression of CHORDC1 mRNA
CTD
PMID:20080153
NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
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Chpf2
chondroitin polymerizing factor 2
increases expression
EXP
Ketamine results in increased expression of CHPF2 mRNA
CTD
PMID:20080153
NCBI chr 4:10,578,470...10,585,940
Ensembl chr 4:10,580,462...10,585,916
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Chrm1
cholinergic receptor, muscarinic 1
multiple interactions
ISO
Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM1 protein]
CTD
PMID:12456425
NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
G
Chrm2
cholinergic receptor, muscarinic 2
multiple interactions
ISO
Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM2 protein]
CTD
PMID:12456425
NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
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Chrm3
cholinergic receptor, muscarinic 3
multiple interactions
ISO
Ketamine inhibits the reaction [Scopolamine Derivatives binds to CHRM3 protein]
CTD
PMID:12456425
NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
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Ciao3
cytosolic iron-sulfur assembly component 3
increases expression
EXP
Ketamine results in increased expression of CIAO3 mRNA
CTD
PMID:20080153
NCBI chr10:14,795,888...14,804,953
Ensembl chr10:14,795,961...14,804,950
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Cldn11
claudin 11
increases expression
EXP
Ketamine results in increased expression of CLDN11 mRNA
CTD
PMID:20080153
NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
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Clec2l
C-type lectin domain family 2, member L
increases expression
EXP
Ketamine results in increased expression of CLEC2L mRNA
CTD
PMID:20080153
NCBI chr 4:67,392,118...67,414,539
Ensembl chr 4:67,397,873...67,414,537
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Clec4a3
C-type lectin domain family 4, member A3
increases expression
EXP
Ketamine results in increased expression of CLEC4A3 mRNA
CTD
PMID:20080153
NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817
G
Clk1
CDC-like kinase 1
decreases expression
EXP
Ketamine results in decreased expression of CLK1 mRNA
CTD
PMID:20080153
NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000
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Clmp
CXADR-like membrane protein
decreases expression
EXP
Ketamine results in decreased expression of CLMP mRNA
CTD
PMID:20080153
NCBI chr 8:41,060,527...41,168,841
Ensembl chr 8:41,060,799...41,168,838
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Clu
clusterin
increases expression
EXP
Ketamine results in increased expression of CLU mRNA
CTD
PMID:20080153
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
increases expression
EXP
Ketamine results in increased expression of CMTM5 mRNA
CTD
PMID:20080153
NCBI chr15:28,412,624...28,415,304
Ensembl chr15:28,412,624...28,415,287
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Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
increases expression
EXP
Ketamine results in increased expression of CMTM8 mRNA
CTD
PMID:20080153
NCBI chr 8:114,481,730...114,547,107
Ensembl chr 8:114,481,982...114,547,083
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Cnksr3
Cnksr family member 3
increases expression
EXP
Ketamine results in increased expression of CNKSR3 mRNA
CTD
PMID:20080153
NCBI chr 1:43,499,273...43,591,630
Ensembl chr 1:43,499,487...43,591,635
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Cnr1
cannabinoid receptor 1
decreases expression
EXP
Ketamine results in decreased expression of CNR1 mRNA
CTD
PMID:20080153
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Coa4
cytochrome c oxidase assembly factor 4 homolog
decreases expression
EXP
Ketamine results in decreased expression of COA4 mRNA
CTD
PMID:20080153
NCBI chr 1:154,882,199...154,885,445
Ensembl chr 1:154,882,155...154,888,174
G
Coa7
cytochrome c oxidase assembly factor 7
increases expression
EXP
Ketamine results in increased expression of COA7 mRNA
CTD
PMID:20080153
NCBI chr 5:123,069,356...123,080,942
Ensembl chr 5:123,069,371...123,080,199
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Cog6
component of oligomeric golgi complex 6
decreases expression
EXP
Ketamine results in decreased expression of COG6 mRNA
CTD
PMID:20080153
NCBI chr 2:137,062,127...137,099,176
Ensembl chr 2:137,061,346...137,099,190
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Col11a1
collagen type XI alpha 1 chain
decreases expression
EXP
Ketamine results in decreased expression of COL11A1 mRNA
CTD
PMID:20080153
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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Commd5
COMM domain containing 5
increases expression
EXP
Ketamine results in increased expression of COMMD5 mRNA
CTD
PMID:20080153
NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764
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Comt
catechol-O-methyltransferase
increases expression
EXP
Ketamine results in increased expression of COMT mRNA
CTD
PMID:20080153
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Coq8a
coenzyme Q8A
increases expression
EXP
Ketamine results in increased expression of COQ8A mRNA
CTD
PMID:20080153
NCBI chr13:91,904,731...91,933,588
Ensembl chr13:91,904,739...91,931,431
G
Cort
cortistatin
increases expression
EXP
Ketamine results in increased expression of CORT mRNA
CTD
PMID:20080153
NCBI chr 5:159,560,591...159,562,032
G
Cox6a2
cytochrome c oxidase subunit 6A2
increases expression
EXP
Ketamine results in increased expression of COX6A2 mRNA
CTD
PMID:20080153
NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
G
Cracdl
CRACD like
increases expression
EXP
Ketamine results in increased expression of CRACDL mRNA
CTD
PMID:20080153
NCBI chr 9:39,834,321...39,950,763
Ensembl chr 9:39,834,833...39,951,086
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Crcp
CGRP receptor component
increases expression
EXP
Ketamine results in increased expression of CRCP mRNA
CTD
PMID:20080153
NCBI chr12:26,623,968...26,659,756
Ensembl chr12:26,623,976...26,768,225
G
Creg1
cellular repressor of E1A-stimulated genes 1
increases expression
EXP
Ketamine results in increased expression of CREG1 mRNA
CTD
PMID:20080153
NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
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Creld2
cysteine-rich with EGF-like domains 2
decreases expression
EXP
Ketamine results in decreased expression of CRELD2 mRNA
CTD
PMID:20080153
NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
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Crh
corticotropin releasing hormone
decreases expression
EXP
Ketamine results in decreased expression of CRH mRNA
CTD
PMID:20080153
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Crls1
cardiolipin synthase 1
decreases expression
EXP
Ketamine results in decreased expression of CRLS1 mRNA
CTD
PMID:20080153
NCBI chr 3:120,119,822...120,138,674
Ensembl chr 3:120,119,852...120,138,655
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Crtac1
cartilage acidic protein 1
increases expression
EXP
Ketamine results in increased expression of CRTAC1 mRNA
CTD
PMID:20080153
NCBI chr 1:241,091,679...241,233,677
Ensembl chr 1:241,078,864...241,233,421
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Cryab
crystallin, alpha B
increases expression
EXP
Ketamine results in increased expression of CRYAB mRNA
CTD
PMID:20080153
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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Ctnnb1
catenin beta 1
increases expression multiple interactions
EXP
Ketamine results in increased expression of CTNNB1 protein Chir 99021 promotes the reaction [Ketamine results in increased expression of CTNNB1 protein]
CTD
PMID:36334642
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Ctse
cathepsin E
increases expression
EXP
Ketamine results in increased expression of CTSE mRNA
CTD
PMID:20080153
NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502
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Ctsk
cathepsin K
increases expression
EXP
Ketamine results in increased expression of CTSK mRNA
CTD
PMID:20080153
NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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Ctss
cathepsin S
increases expression
EXP
Ketamine results in increased expression of CTSS mRNA
CTD
PMID:20080153
NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
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Cttnbp2nl
CTTNBP2 N-terminal like
decreases expression
EXP
Ketamine results in decreased expression of CTTNBP2NL mRNA
CTD
PMID:20080153
NCBI chr 2:192,507,963...192,554,548
Ensembl chr 2:192,507,963...192,541,101
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Cx3cl1
C-X3-C motif chemokine ligand 1
increases expression
EXP
Ketamine results in increased expression of CX3CL1 mRNA
CTD
PMID:20080153
NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions
ISO
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of CXCL1 protein]
CTD
PMID:22245128
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cxxc4
CXXC finger protein 4
decreases expression
EXP
Ketamine results in decreased expression of CXXC4 mRNA
CTD
PMID:20080153
NCBI chr 2:222,664,148...222,689,365
Ensembl chr 2:222,664,771...222,689,365
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Cyb5r3
cytochrome b5 reductase 3
increases expression
EXP
Ketamine results in increased expression of CYB5R3 mRNA
CTD
PMID:20080153
NCBI chr 7:114,306,686...114,324,247
Ensembl chr 7:114,306,685...114,324,298
G
Cyba
cytochrome b-245 alpha chain
increases expression
ISO
Ketamine results in increased expression of CYBA
CTD
PMID:18063801
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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Cybb
cytochrome b-245 beta chain
increases expression
ISO
Ketamine results in increased expression of CYBB
CTD
PMID:18063801
NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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Cyp11a1
cytochrome P450, family 11, subfamily a, polypeptide 1
increases expression
EXP
Ketamine results in increased expression of CYP11A1 mRNA
CTD
PMID:20080153
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression
EXP
Ketamine results in increased expression of CYP1A1 protein
CTD
PMID:16076768
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
Ketamine results in increased expression of CYP2B1 protein
CTD
PMID:16076768
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
increases expression
EXP
Ketamine results in increased expression of CYP2E1 protein
CTD
PMID:16076768
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression decreases expression multiple interactions
EXP ISO
Ketamine results in increased expression of CYP3A2 protein Ketamine results in decreased expression of CYP3A4 mRNA Ketamine results in decreased expression of and results in decreased activity of CYP3A4 protein
CTD
PMID:16076768 PMID:18845661
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
increases expression
EXP
Ketamine results in increased expression of CYP3A23-3A1 protein
CTD
PMID:16076768
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
increases expression
EXP
Ketamine results in increased expression of CYP46A1 mRNA
CTD
PMID:20080153
NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760
G
Cyth4
cytohesin 4
decreases expression multiple interactions
EXP
Ketamine results in decreased expression of CYTH4 mRNA Cannabidiol inhibits the reaction [Ketamine results in decreased expression of CYTH4 mRNA]
CTD
PMID:31823199
NCBI chr 7:110,152,232...110,176,726
Ensembl chr 7:110,152,272...110,176,741
G
Daglb
diacylglycerol lipase, beta
decreases expression
EXP
Ketamine results in decreased expression of DAGLB mRNA
CTD
PMID:20080153
NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154
G
Dbndd1
dysbindin domain containing 1
decreases expression
EXP
Ketamine results in decreased expression of DBNDD1 mRNA
CTD
PMID:20080153
NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444
G
Dcaf13
DDB1 and CUL4 associated factor 13
decreases expression
EXP
Ketamine results in decreased expression of DCAF13 mRNA
CTD
PMID:20080153
NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142
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Dctd
dCMP deaminase
decreases expression
EXP
Ketamine results in decreased expression of DCTD mRNA
CTD
PMID:20080153
NCBI chr16:44,066,952...44,098,654
Ensembl chr16:44,055,128...44,098,446
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Ddit3
DNA-damage inducible transcript 3
increases expression multiple interactions
ISO
Ketamine results in increased expression of DDIT3 mRNA Ketamine results in increased expression of DDIT3 protein LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]
CTD
PMID:35728656 PMID:36907275
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
G
Ddx31
DEAD-box helicase 31
decreases expression
EXP
Ketamine results in decreased expression of DDX31 mRNA
CTD
PMID:20080153
NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873
G
Defb1
defensin beta 1
decreases expression
EXP
Ketamine results in decreased expression of DEFB1 mRNA
CTD
PMID:20080153
NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
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Dennd2b
DENN domain containing 2B
increases expression
EXP
Ketamine results in increased expression of DENND2B mRNA
CTD
PMID:20080153
NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680
G
Dgat2
diacylglycerol O-acyltransferase 2
increases expression
EXP
Ketamine results in increased expression of DGAT2 mRNA
CTD
PMID:20080153
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
G
Dhodh
dihydroorotate dehydrogenase (quinone)
decreases expression
EXP
Ketamine results in decreased expression of DHODH mRNA
CTD
PMID:20080153
NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
G
Dhx36
DEAH-box helicase 36
decreases expression
EXP
Ketamine results in decreased expression of DHX36 mRNA
CTD
PMID:20080153
NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
G
Dipk1a
divergent protein kinase domain 1A
increases expression
EXP
Ketamine results in increased expression of DIPK1A mRNA
CTD
PMID:20080153
NCBI chr14:1,772,412...1,843,508
Ensembl chr14:1,772,422...1,843,743
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Dlg4
discs large MAGUK scaffold protein 4
decreases expression multiple interactions increases expression
ISO
Ketamine results in decreased expression of DLG4 protein Ketamine inhibits the reaction [Corticosterone results in decreased expression of DLG4 protein]; Sirolimus inhibits the reaction [Ketamine results in increased expression of DLG4 protein]
CTD
PMID:31470060 PMID:33022268 PMID:33872575
NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
G
Dlx5
distal-less homeobox 5
decreases expression
EXP
Ketamine results in decreased expression of DLX5 mRNA
CTD
PMID:20080153
NCBI chr 4:34,999,139...35,003,504
Ensembl chr 4:34,999,139...35,003,407
G
Dmac1
distal membrane arm assembly component 1
decreases expression
EXP
Ketamine results in decreased expression of DMAC1 mRNA
CTD
PMID:20080153
NCBI chr 5:89,241,173...89,243,793
Ensembl chr 5:89,242,661...89,243,757
G
Dmrtc1a
DMRT-like family C1a
increases expression
EXP
Ketamine results in increased expression of DMRTC1A mRNA
CTD
PMID:20080153
NCBI chr X:67,822,187...67,852,572
Ensembl chr X:67,822,113...67,852,571
G
Dmtf1
cyclin D binding myb-like transcription factor 1
decreases expression
EXP
Ketamine results in decreased expression of DMTF1 mRNA
CTD
PMID:20080153
NCBI chr 4:24,909,937...24,950,786
Ensembl chr 4:24,910,534...24,950,967
G
Dnajb14
DnaJ heat shock protein family (Hsp40) member B14
decreases expression
EXP
Ketamine results in decreased expression of DNAJB14 mRNA
CTD
PMID:20080153
NCBI chr 2:226,358,988...226,409,461
Ensembl chr 2:226,358,996...226,402,490
G
Dnajc15
DnaJ heat shock protein family (Hsp40) member C15
decreases expression
EXP
Ketamine results in decreased expression of DNAJC15 mRNA
CTD
PMID:20080153
NCBI chr15:53,182,060...53,249,675
Ensembl chr15:53,184,855...53,249,675
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Dnm1
dynamin 1
increases expression
EXP
Ketamine results in increased expression of DNM1 mRNA
CTD
PMID:20080153
NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538
G
Dnmt3b
DNA methyltransferase 3 beta
decreases expression
EXP
Ketamine results in decreased expression of DNMT3B mRNA
CTD
PMID:20080153
NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
G
Dock11
dedicator of cytokinesis 11
decreases expression
EXP
Ketamine results in decreased expression of DOCK11 mRNA
CTD
PMID:20080153
NCBI chr X:115,131,720...115,314,854
Ensembl chr X:115,131,909...115,314,854
G
Dph5
diphthamide biosynthesis 5
decreases expression
EXP
Ketamine results in decreased expression of DPH5 mRNA
CTD
PMID:20080153
NCBI chr 2:203,804,620...203,858,196
Ensembl chr 2:203,804,936...203,840,433
G
Dpysl3
dihydropyrimidinase-like 3
decreases expression
EXP
Ketamine results in decreased expression of DPYSL3 mRNA
CTD
PMID:20080153
NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157
G
Drd2
dopamine receptor D2
affects binding
EXP
Ketamine binds to Drd2 protein
RGD
PMID:15852061
RGD:1581406
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
G
Dtx4
deltex E3 ubiquitin ligase 4
decreases expression
EXP
Ketamine results in decreased expression of DTX4 mRNA
CTD
PMID:20080153
NCBI chr 1:209,457,719...209,545,163
Ensembl chr 1:209,460,735...209,492,818
G
Dusp11
dual specificity phosphatase 11
decreases expression
EXP
Ketamine results in decreased expression of DUSP11 mRNA
CTD
PMID:20080153
NCBI chr 4:118,367,673...118,385,183
Ensembl chr 4:118,368,053...118,385,181
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Dusp22
dual specificity phosphatase 22
increases expression
EXP
Ketamine results in increased expression of DUSP22 mRNA
CTD
PMID:20080153
NCBI chr17:33,780,980...33,831,241
Ensembl chr17:33,780,981...33,831,321
G
Dync2i2
dynein 2 intermediate chain 2
decreases expression
EXP
Ketamine results in decreased expression of DYNC2I2 mRNA
CTD
PMID:20080153
NCBI chr 3:13,306,039...13,322,121
Ensembl chr 3:13,306,039...13,322,121
G
Ears2
glutamyl-tRNA synthetase 2, mitochondrial
decreases expression
EXP
Ketamine results in decreased expression of EARS2 mRNA
CTD
PMID:20080153
NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
G
Ebp
EBP, cholestenol delta-isomerase
decreases expression
EXP
Ketamine results in decreased expression of EBP mRNA
CTD
PMID:20080153
NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
G
Ebpl
EBP like
decreases expression
EXP
Ketamine results in decreased expression of EBPL mRNA
CTD
PMID:20080153
NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472
G
Echs1
enoyl-CoA hydratase, short chain 1
increases expression
EXP
Ketamine results in increased expression of ECHS1 protein
CTD
PMID:18504422
NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
G
Ect2
epithelial cell transforming 2
decreases expression
EXP
Ketamine results in decreased expression of ECT2 mRNA
CTD
PMID:20080153
NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
G
Edc3
enhancer of mRNA decapping 3
increases expression
EXP
Ketamine results in increased expression of EDC3 mRNA
CTD
PMID:20080153
NCBI chr 8:58,106,147...58,151,685
Ensembl chr 8:58,106,175...58,151,671
G
Eef2k
eukaryotic elongation factor-2 kinase
decreases expression
EXP
Ketamine results in decreased expression of EEF2K mRNA
CTD
PMID:20080153
NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164
G
Efhb
EF hand domain family, member B
increases expression
EXP
Ketamine results in increased expression of EFHB mRNA
CTD
PMID:20080153
NCBI chr 9:6,372,191...6,441,678
Ensembl chr 9:6,372,194...6,441,919
G
Efna2
ephrin A2
decreases expression
EXP
Ketamine results in decreased expression of EFNA2 mRNA
CTD
PMID:20080153
NCBI chr 7:9,515,635...9,528,071
Ensembl chr 7:9,516,429...9,527,061
G
Egr4
early growth response 4
decreases expression
EXP
Ketamine results in decreased expression of EGR4 mRNA
CTD
PMID:20080153
NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
G
Eif1a
eukaryotic translation initiation factor 1A
decreases expression
EXP
Ketamine results in decreased expression of EIF1A mRNA
CTD
PMID:20080153
NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696
G
Eif4e3
eukaryotic translation initiation factor 4E family member 3
decreases expression
EXP
Ketamine results in decreased expression of EIF4E3 mRNA
CTD
PMID:20080153
NCBI chr 4:132,258,502...132,301,808
Ensembl chr 4:132,258,502...132,301,808
G
Eno2
enolase 2
decreases expression
EXP
Ketamine results in decreased expression of ENO2 protein
CTD
PMID:18504422
NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
G
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
increases expression
EXP
Ketamine results in increased expression of ENPP2 mRNA
CTD
PMID:20080153
NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
G
Entrep1
endosomal transmembrane epsin interactor 1
increases expression
EXP
Ketamine results in increased expression of ENTREP1 mRNA
CTD
PMID:20080153
NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758
G
Ephx4
epoxide hydrolase 4
increases expression
EXP
Ketamine results in increased expression of EPHX4 mRNA
CTD
PMID:20080153
NCBI chr14:2,343,376...2,372,680
Ensembl chr14:2,340,248...2,373,022
G
Erbb4
erb-b2 receptor tyrosine kinase 4
decreases expression
ISO
Ketamine results in decreased expression of ERBB4 mRNA
CTD
PMID:20000043
NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
G
Erich1
glutamate-rich 1
decreases expression
EXP
Ketamine results in decreased expression of ERICH1 mRNA
CTD
PMID:20080153
NCBI chr16:75,501,322...75,569,129
Ensembl chr16:75,501,384...75,569,128
G
Ermp1
endoplasmic reticulum metallopeptidase 1
increases expression
EXP
Ketamine results in increased expression of ERMP1 mRNA
CTD
PMID:20080153
NCBI chr 1:227,383,992...227,422,120
Ensembl chr 1:227,387,920...227,436,909
G
Ezh1
enhancer of zeste 1 polycomb repressive complex 2 subunit
increases expression
EXP
Ketamine results in increased expression of EZH1 mRNA
CTD
PMID:20080153
NCBI chr10:86,126,023...86,162,001
Ensembl chr10:86,126,015...86,161,921
G
Ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
decreases expression
EXP
Ketamine results in decreased expression of EZH2 mRNA
CTD
PMID:20080153
NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
G
Fam110d
family with sequence similarity 110, member D
decreases expression
EXP
Ketamine results in decreased expression of FAM110D mRNA
CTD
PMID:20080153
NCBI chr 5:146,471,048...146,474,019
Ensembl chr 5:146,471,049...146,474,056
G
Fam120b
family with sequence similarity 120 member B
decreases expression
EXP
Ketamine results in decreased expression of FAM120B mRNA
CTD
PMID:20080153
NCBI chr 1:56,320,015...56,385,064
Ensembl chr 1:56,339,129...56,385,061
G
Fam136a
family with sequence similarity 136, member A
decreases expression
EXP
Ketamine results in decreased expression of FAM136A mRNA
CTD
PMID:20080153
NCBI chr 4:118,805,129...118,811,046
Ensembl chr 4:118,805,127...118,811,047
G
Fam180a
family with sequence similarity 180, member A
decreases expression
EXP
Ketamine results in decreased expression of FAM180A mRNA
CTD
PMID:20080153
NCBI chr 4:63,992,867...64,008,047
Ensembl chr 4:63,992,867...64,008,047
G
Fam210a
family with sequence similarity 210, member A
decreases expression
EXP
Ketamine results in decreased expression of FAM210A mRNA
CTD
PMID:20080153
NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
G
Fam98a
family with sequence similarity 98, member A
decreases expression
EXP
Ketamine results in decreased expression of FAM98A mRNA
CTD
PMID:20080153
NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742
G
Fat3
FAT atypical cadherin 3
decreases expression
EXP
Ketamine results in decreased expression of FAT3 mRNA
CTD
PMID:20080153
NCBI chr 8:12,691,470...13,274,336
Ensembl chr 8:12,694,019...13,273,135
G
Fat4
FAT atypical cadherin 4
decreases expression
EXP
Ketamine results in decreased expression of FAT4 mRNA
CTD
PMID:20080153
NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707
G
Faxc
failed axon connections homolog, metaxin like GST domain containing
increases expression
EXP
Ketamine results in increased expression of FAXC mRNA
CTD
PMID:20080153
NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446
G
Fbl
fibrillarin
decreases expression
EXP
Ketamine results in decreased expression of FBL mRNA
CTD
PMID:20080153
NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
G
Fblim1
filamin binding LIM protein 1
decreases expression
EXP
Ketamine results in decreased expression of FBLIM1 mRNA
CTD
PMID:20080153
NCBI chr 5:153,883,945...153,915,524
Ensembl chr 5:153,883,960...153,913,757
G
Fbxl22
F-box and leucine-rich repeat protein 22
increases expression
EXP
Ketamine results in increased expression of FBXL22 mRNA
CTD
PMID:20080153
NCBI chr 8:67,069,998...67,076,685
Ensembl chr 8:67,069,998...67,076,685
G
Fbxo2
F-box protein 2
increases expression
EXP
Ketamine results in increased expression of FBXO2 mRNA
CTD
PMID:20080153
NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355
G
Fbxo34
F-box protein 34
increases expression
EXP
Ketamine results in increased expression of FBXO34 mRNA
CTD
PMID:20080153
NCBI chr15:20,719,395...20,787,905
Ensembl chr15:20,710,629...20,787,222
G
Fbxo8
F-box protein 8
increases expression
EXP
Ketamine results in increased expression of FBXO8 mRNA
CTD
PMID:20080153
NCBI chr16:33,665,305...33,711,215
Ensembl chr16:33,665,306...33,711,272
G
Fdft1
farnesyl diphosphate farnesyl transferase 1
decreases expression
EXP
Ketamine results in decreased expression of FDFT1 mRNA
CTD
PMID:20080153
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
G
Fem1b
fem-1 homolog B
increases expression
EXP
Ketamine results in increased expression of FEM1B mRNA
CTD
PMID:20080153
NCBI chr 8:63,265,301...63,278,577
Ensembl chr 8:63,265,301...63,278,577
G
Fgfr3
fibroblast growth factor receptor 3
increases expression
EXP
Ketamine results in increased expression of FGFR3 mRNA
CTD
PMID:20080153
NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
G
Fgfrl1
fibroblast growth factor receptor-like 1
decreases expression
EXP
Ketamine results in decreased expression of FGFRL1 mRNA
CTD
PMID:20080153
NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928
G
Fkbp15
FKBP prolyl isomerase family member 15
increases expression
EXP
Ketamine results in increased expression of FKBP15 mRNA
CTD
PMID:20080153
NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
G
Fn1
fibronectin 1
increases expression multiple interactions
EXP ISO
Ketamine results in increased expression of FN1 protein Ketamine results in increased expression of FN1 mRNA; Ketamine results in increased expression of FN1 protein 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in increased expression of FN1 protein]
CTD
PMID:28331066
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
G
Fn3k
fructosamine 3 kinase
increases expression
EXP
Ketamine results in increased expression of FN3K mRNA
CTD
PMID:20080153
NCBI chr10:106,700,670...106,715,903
Ensembl chr10:106,700,670...106,715,895
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions
EXP
Ketamine inhibits the reaction [Formaldehyde results in increased expression of FOS protein]
CTD
PMID:17551412
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Foxo1
forkhead box O1
decreases expression
EXP
Ketamine results in decreased expression of FOXO1 mRNA
CTD
PMID:20080153
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
G
Frem3
FRAS1 related extracellular matrix 3
increases expression
EXP
Ketamine results in increased expression of FREM3 mRNA
CTD
PMID:20080153
NCBI chr19:27,308,469...27,366,771
Ensembl chr19:27,308,469...27,366,771
G
Fubp1
far upstream element binding protein 1
decreases expression
EXP
Ketamine results in decreased expression of FUBP1 mRNA
CTD
PMID:20080153
NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
G
Fxyd7
FXYD domain-containing ion transport regulator 7
increases expression
EXP
Ketamine results in increased expression of FXYD7 mRNA
CTD
PMID:20080153
NCBI chr 1:86,277,678...86,286,954
Ensembl chr 1:86,277,678...86,286,954
G
G0s2
G0/G1switch 2
decreases expression
EXP
Ketamine results in decreased expression of G0S2 mRNA
CTD
PMID:20080153
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
G
Gabra5
gamma-aminobutyric acid type A receptor subunit alpha 5
increases expression
ISO
Ketamine results in increased expression of GABRA5 mRNA; Ketamine results in increased expression of GABRA5 protein
CTD
PMID:21712993
NCBI chr 1:108,268,728...108,381,670
Ensembl chr 1:108,268,776...108,380,917
G
Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
decreases expression
EXP
Ketamine results in decreased expression of GABRB2 mRNA
CTD
PMID:20080153
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
G
Gabrd
gamma-aminobutyric acid type A receptor subunit delta
increases expression
EXP
Ketamine results in increased expression of GABRD mRNA
CTD
PMID:20080153
NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
decreases expression
EXP
Ketamine results in decreased expression of GABRG2 mRNA
CTD
PMID:20080153
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
G
Gad1
glutamate decarboxylase 1
multiple interactions increases expression decreases expression
ISO
acetovanillone inhibits the reaction [Ketamine results in decreased expression of GAD1 protein] Ketamine results in increased expression of GAD1 mRNA
CTD
PMID:18063801 PMID:23660488
NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
G
Galnt16
polypeptide N-acetylgalactosaminyltransferase 16
increases expression
EXP
Ketamine results in increased expression of GALNT16 mRNA
CTD
PMID:20080153
NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
G
Galr2
galanin receptor 2
decreases expression
EXP
Ketamine results in decreased expression of GALR2 mRNA
CTD
PMID:20080153
NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
G
Gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
increases expression
EXP
Ketamine results in increased expression of GAPDHS mRNA
CTD
PMID:20080153
NCBI chr 1:85,979,096...85,994,153
Ensembl chr 1:85,979,098...85,993,640
G
Garin5a
golgi associated RAB2 interactor 5A
increases expression
EXP
Ketamine results in increased expression of GARIN5A mRNA
CTD
PMID:20080153
NCBI chr 1:94,988,959...94,995,971
Ensembl chr 1:94,988,613...94,993,539
G
Gatad2b
GATA zinc finger domain containing 2B
decreases expression
EXP
Ketamine results in decreased expression of GATAD2B mRNA
CTD
PMID:20080153
NCBI chr 2:175,748,594...175,829,837
Ensembl chr 2:175,749,433...175,825,542
G
Gca
grancalcin
decreases expression
EXP
Ketamine results in decreased expression of GCA mRNA
CTD
PMID:20080153
NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression multiple interactions decreases expression
EXP
Ketamine results in increased expression of GCLC mRNA Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of GCLC protein] Ketamine results in decreased expression of GCLC mRNA; Ketamine results in decreased expression of GCLC protein
CTD
PMID:20080153 PMID:36305173
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Gdap1l1
ganglioside-induced differentiation-associated protein 1-like 1
increases expression
EXP
Ketamine results in increased expression of GDAP1L1 mRNA
CTD
PMID:20080153
NCBI chr 3:152,110,225...152,129,693
Ensembl chr 3:152,110,253...152,128,711
G
Gfap
glial fibrillary acidic protein
increases expression
EXP
Ketamine results in increased expression of GFAP mRNA
CTD
PMID:20080153
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
G
Gfod2
Gfo/Idh/MocA-like oxidoreductase domain containing 2
decreases expression
EXP
Ketamine results in decreased expression of GFOD2 mRNA
CTD
PMID:20080153
NCBI chr19:33,599,689...33,647,060
Ensembl chr19:33,604,187...33,647,004
G
Gfpt2
glutamine-fructose-6-phosphate transaminase 2
decreases expression
EXP
Ketamine results in decreased expression of GFPT2 mRNA
CTD
PMID:20080153
NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329
G
Ggact
gamma-glutamylamine cyclotransferase
increases expression
EXP
Ketamine results in increased expression of GGACT mRNA
CTD
PMID:20080153
NCBI chr15:99,969,246...99,998,343
Ensembl chr15:99,968,282...99,993,455
G
Gjb6
gap junction protein, beta 6
increases expression
EXP
Ketamine results in increased expression of GJB6 mRNA
CTD
PMID:20080153
NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582
G
Glul
glutamate-ammonia ligase
increases expression multiple interactions
EXP ISO
Ketamine results in increased expression of GLUL protein [Guanosine co-treated with Ketamine] results in increased activity of GLUL protein
CTD
PMID:18504422 PMID:36878458
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
G
Gpr22
G protein-coupled receptor 22
increases expression
EXP
Ketamine results in increased expression of GPR22 mRNA
CTD
PMID:20080153
NCBI chr 6:48,309,619...48,317,864
Ensembl chr 6:48,310,505...48,317,486
G
Gpr37l1
G protein-coupled receptor 37-like 1
increases expression
EXP
Ketamine results in increased expression of GPR37L1 mRNA
CTD
PMID:20080153
NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
G
Gpr84
G protein-coupled receptor 84
multiple interactions decreases expression
EXP
Cannabidiol inhibits the reaction [Ketamine results in decreased expression of GPR84 mRNA]
CTD
PMID:31823199
NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178
G
Gpr85
G protein-coupled receptor 85
decreases expression
EXP
Ketamine results in decreased expression of GPR85 mRNA
CTD
PMID:20080153
NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566
G
Gria1
glutamate ionotropic receptor AMPA type subunit 1
decreases expression multiple interactions
ISO EXP
Ketamine results in decreased expression of GRIA1 protein Ketamine promotes the reaction [Methamphetamine increases expression of Gria1 protein in hippocampus, striatum] Ketamine inhibits the reaction [Corticosterone results in decreased expression of GRIA1 protein]; MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein]
CTD RGD
PMID:31470060 PMID:33872575 PMID:37778205
RGD:405100237
NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
G
Gria2
glutamate ionotropic receptor AMPA type subunit 2
multiple interactions decreases expression
ISO
MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein]
CTD
PMID:31470060
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
G
Grik5
glutamate ionotropic receptor kainate type subunit 5
increases expression
EXP
Ketamine results in increased expression of GRIK5 mRNA
CTD
PMID:20080153
NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
G
Grin1
glutamate ionotropic receptor NMDA type subunit 1
increases expression
EXP
Ketamine results in increased expression of GRIN1 mRNA; Ketamine results in increased expression of GRIN1 protein
CTD
PMID:19126600 PMID:20080153 PMID:23065140
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
G
Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
affects response to substance increases expression
ISO EXP
GRIN2A protein affects the susceptibility to Ketamine Ketamine results in increased expression of GRIN2A mRNA
CTD
PMID:15731593 PMID:20080153
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
G
Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
multiple interactions
EXP
Ketamine inhibits the reaction [remifentanil results in increased phosphorylation of GRIN2B protein]
CTD
PMID:20042082
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
G
Grin2c
glutamate ionotropic receptor NMDA type subunit 2C
increases expression
EXP
Ketamine results in increased expression of GRIN2C mRNA
CTD
PMID:20080153
NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
G
Grm3
glutamate metabotropic receptor 3
decreases expression
EXP
Ketamine results in decreased expression of GRM3 mRNA
CTD
PMID:20080153
NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
G
Gsk3b
glycogen synthase kinase 3 beta
decreases phosphorylation multiple interactions increases phosphorylation
EXP
Ketamine results in decreased phosphorylation of GSK3B protein Chir 99021 inhibits the reaction [Ketamine results in increased phosphorylation of GSK3B protein]
CTD
PMID:17952604 PMID:36334642
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsto2
glutathione S-transferase omega 2
increases expression
EXP
Ketamine results in increased expression of GSTO2 mRNA
CTD
PMID:20080153
NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
G
Gtf2h3
general transcription factor IIH subunit 3
decreases expression
EXP
Ketamine results in decreased expression of GTF2H3 mRNA
CTD
PMID:20080153
NCBI chr12:32,009,010...32,025,484
Ensembl chr12:32,009,014...32,025,497
G
Gtf2ird1
GTF2I repeat domain containing 1
increases expression
EXP
Ketamine results in increased expression of GTF2IRD1 mRNA
CTD
PMID:20080153
NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040
G
Gucy1b1
guanylate cyclase 1 soluble subunit beta 1
decreases expression
EXP
Ketamine results in decreased expression of GUCY1B1 mRNA
CTD
PMID:20080153
NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
G
Habp4
hyaluronan binding protein 4
increases expression
EXP
Ketamine results in increased expression of HABP4 mRNA
CTD
PMID:20080153
NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565
G
Hacd3
3-hydroxyacyl-CoA dehydratase 3
decreases expression
EXP
Ketamine results in decreased expression of HACD3 mRNA
CTD
PMID:20080153
NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507
G
Hap1
huntingtin-associated protein 1
increases expression
EXP
Ketamine results in increased expression of HAP1 mRNA
CTD
PMID:20080153
NCBI chr10:85,277,890...85,286,126
Ensembl chr10:85,277,890...85,286,126
G
Haus8
HAUS augmin-like complex, subunit 8
decreases expression
EXP
Ketamine results in decreased expression of HAUS8 mRNA
CTD
PMID:20080153
NCBI chr16:17,930,819...17,945,254
Ensembl chr16:17,930,820...17,945,237
G
Havcr1
hepatitis A virus cellular receptor 1
multiple interactions
ISO
[Ketamine co-treated with Xylazine] results in increased secretion of HAVCR1 protein
CTD
PMID:30538007
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
G
Hbb
hemoglobin subunit beta
decreases expression
EXP
Ketamine results in decreased expression of HBB-B1 mRNA
CTD
PMID:20080153
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
G
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
decreases expression
EXP
Ketamine results in decreased expression of HECW1 mRNA
CTD
PMID:20080153
NCBI chr17:50,671,239...51,084,536
Ensembl chr17:50,670,954...51,080,720
G
Hes5
hes family bHLH transcription factor 5
decreases expression
EXP
Ketamine results in decreased expression of HES5 mRNA
CTD
PMID:20080153
NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001
G
Hes6
hes family bHLH transcription factor 6
decreases expression
EXP
Ketamine results in decreased expression of HES6 mRNA
CTD
PMID:20080153
NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
G
Hibch
3-hydroxyisobutyryl-CoA hydrolase
decreases expression
EXP
Ketamine results in decreased expression of HIBCH mRNA
CTD
PMID:20080153
NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824
G
Hmgcll1
3-hydroxy-3-methylglutaryl-CoA lyase like 1
decreases expression
EXP
Ketamine results in decreased expression of HMGCLL1 mRNA
CTD
PMID:20080153
NCBI chr 8:76,757,301...76,887,300
Ensembl chr 8:76,757,497...76,886,816
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
EXP
Ketamine results in decreased expression of HMGCR mRNA
CTD
PMID:20080153
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Hmgcs2
3-hydroxy-3-methylglutaryl-CoA synthase 2
increases expression
EXP
Ketamine results in increased expression of HMGCS2 mRNA
CTD
PMID:20080153
NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
G
Hmgn1
high mobility group nucleosome binding domain 1
decreases expression
EXP
Ketamine results in decreased expression of HMGN1 mRNA
CTD
PMID:20080153
NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
G
Hmgn3
high mobility group nucleosomal binding domain 3
increases expression
EXP
Ketamine results in increased expression of HMGN3 mRNA
CTD
PMID:20080153
NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976
G
Hmox1
heme oxygenase 1
decreases expression multiple interactions
EXP
Ketamine results in decreased expression of HMOX1 mRNA; Ketamine results in decreased expression of HMOX1 protein Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of HMOX1 protein]
CTD
PMID:36305173
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hmox2
heme oxygenase 2
increases expression
EXP
Ketamine results in increased expression of HMOX2 mRNA
CTD
PMID:20080153
NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
G
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
increases expression
EXP
Ketamine results in increased expression of HNRNPA2B1 protein
CTD
PMID:18504422
NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
G
Hnrnph3
heterogeneous nuclear ribonucleoprotein H3
decreases expression
EXP
Ketamine results in decreased expression of HNRNPH3 mRNA
CTD
PMID:20080153
NCBI chr20:25,616,400...25,625,814
Ensembl chr20:25,614,733...25,625,750
G
Hopx
HOP homeobox
increases expression
EXP
Ketamine results in increased expression of HOPX mRNA
CTD
PMID:20080153
NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909
G
Hpca
hippocalcin
increases expression
EXP
Ketamine results in increased expression of HPCA mRNA
CTD
PMID:20080153
NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
G
Hpdl
4-hydroxyphenylpyruvate dioxygenase-like
decreases expression
EXP
Ketamine results in decreased expression of HPDL mRNA
CTD
PMID:20080153
NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233
G
Hpgd
15-hydroxyprostaglandin dehydrogenase
decreases expression
EXP
Ketamine results in decreased expression of HPGD mRNA
CTD
PMID:20080153
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
G
Hras
HRas proto-oncogene, GTPase
multiple interactions
ISO
Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of HRAS protein]
CTD
PMID:19540866
NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
G
Hrh3
histamine receptor H3
increases expression
EXP
Ketamine results in increased expression of HRH3 mRNA
CTD
PMID:20080153
NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642
G
Hrk
harakiri, BCL2 interacting protein
increases expression
EXP
Ketamine results in increased expression of HRK mRNA
CTD
PMID:20080153
NCBI chr12:38,387,484...38,409,652
G
Hs3st5
heparan sulfate-glucosamine 3-sulfotransferase 5
decreases expression
EXP
Ketamine results in decreased expression of HS3ST5 mRNA
CTD
PMID:20080153
NCBI chr20:40,106,876...40,417,661
Ensembl chr20:40,106,876...40,417,653
G
Hsd11b1
hydroxysteroid 11-beta dehydrogenase 1
increases expression
EXP
Ketamine results in increased expression of HSD11B1 mRNA
CTD
PMID:20080153
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
G
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
decreases expression
EXP
Ketamine results in decreased expression of HSD17B4 mRNA
CTD
PMID:20080153
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
G
Hspa2
heat shock protein family A (Hsp70) member 2
increases expression
EXP
Ketamine results in increased expression of HSPA2 mRNA
CTD
PMID:20080153
NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
G
Hspa5
heat shock protein family A (Hsp70) member 5
decreases expression increases expression multiple interactions affects expression
EXP ISO
Ketamine results in decreased expression of HSPA5 mRNA Ketamine results in increased expression of HSPA5 protein LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein] Ketamine affects the expression of HSPA5 mRNA
CTD
PMID:20080153 PMID:35728656 PMID:36907275
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
G
Htra1
HtrA serine peptidase 1
increases expression
EXP
Ketamine results in increased expression of HTRA1 mRNA
CTD
PMID:20080153
NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
G
Icam1
intercellular adhesion molecule 1
multiple interactions
ISO
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of ICAM1 protein]
CTD
PMID:22245128
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Icam5
intercellular adhesion molecule 5
increases expression
EXP
Ketamine results in increased expression of ICAM5 mRNA
CTD
PMID:20080153
NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588
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Idh1
isocitrate dehydrogenase (NADP(+)) 1
decreases expression
EXP
Ketamine results in decreased expression of IDH1 mRNA
CTD
PMID:20080153
NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
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Idi1
isopentenyl-diphosphate delta isomerase 1
decreases expression
EXP
Ketamine results in decreased expression of IDI1 mRNA
CTD
PMID:20080153
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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Ifi27
interferon, alpha-inducible protein 27
increases expression
EXP
Ketamine results in increased expression of IFI27 mRNA
CTD
PMID:20080153
NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294
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Ifi27l2b
interferon, alpha-inducible protein 27 like 2B
increases expression
EXP
Ketamine results in increased expression of IFI27L1 mRNA
CTD
PMID:20080153
NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360
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Ifitm10
interferon induced transmembrane protein 10
increases expression
EXP
Ketamine results in increased expression of IFITM10 mRNA
CTD
PMID:20080153
NCBI chr 1:197,507,501...197,524,180
Ensembl chr 1:197,507,503...197,525,151
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Ifngr1
interferon gamma receptor 1
increases expression
EXP
Ketamine results in increased expression of IFNGR1 mRNA
CTD
PMID:20080153
NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785
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Ifngr2
interferon gamma receptor 2
increases expression
EXP
Ketamine results in increased expression of IFNGR2 mRNA
CTD
PMID:20080153
NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
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Igfbp1
insulin-like growth factor binding protein 1
increases expression
EXP
Ketamine results in increased expression of IGFBP1 mRNA
CTD
PMID:20080153
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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Igfbp3
insulin-like growth factor binding protein 3
increases expression
EXP
Ketamine results in increased expression of IGFBP3 mRNA
CTD
PMID:20080153
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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Igfbpl1
insulin-like growth factor binding protein-like 1
decreases expression
EXP
Ketamine results in decreased expression of IGFBPL1 mRNA
CTD
PMID:20080153
NCBI chr 5:60,076,428...60,091,833
Ensembl chr 5:60,076,429...60,091,833
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Igsf9
immunoglobulin superfamily, member 9
decreases expression
EXP
Ketamine results in decreased expression of IGSF9 mRNA
CTD
PMID:20080153
NCBI chr13:84,948,643...84,965,616
Ensembl chr13:84,948,619...84,965,607
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Ikbip
IKBKB interacting protein
decreases expression
EXP
Ketamine results in decreased expression of IKBIP mRNA
CTD
PMID:20080153
NCBI chr 7:25,579,865...25,598,548
Ensembl chr 7:25,579,832...25,605,162
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Il12a
interleukin 12A
increases expression
EXP
Ketamine results in increased expression of IL12A mRNA
CTD
PMID:20080153
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
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Il1b
interleukin 1 beta
increases expression increases secretion multiple interactions
EXP ISO
Ketamine results in increased expression of IL1B mRNA; Ketamine results in increased expression of IL1B protein Ketamine results in increased secretion of IL1B protein [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of IL1B protein]; Ketamine inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]] Ozone inhibits the reaction [Ketamine results in increased expression of IL1B mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of IL1B protein]
CTD
PMID:15207037 PMID:15207038 PMID:19540866 PMID:22245128 PMID:33536391 PMID:34487425 PMID:37491939 PMID:37515540 More...
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
multiple interactions increases expression affects response to substance
ISO EXP
Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] TRPV4 protein affects the reaction [Ketamine results in increased expression of IL6 protein] [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 mRNA]; [Atropine co-treated with Ketamine] inhibits the reaction [Soman results in increased expression of IL6 protein]; Ketamine inhibits the reaction [Acetaminophen results in increased expression of IL6 protein]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [Ketamine results in increased expression of IL6 protein] Ketamine results in increased expression of IL6 mRNA; Ketamine results in increased expression of IL6 protein IL6 affects the susceptibility to Ketamine
CTD
PMID:15207037 PMID:15207038 PMID:15720977 PMID:19091984 PMID:19540866 PMID:22245128 PMID:23087136 PMID:33536391 PMID:34487425 PMID:37491939 More...
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Ina
internexin neuronal intermediate filament protein, alpha
increases expression
EXP
Ketamine results in increased expression of INA protein
CTD
PMID:18504422
NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330
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Ing2
inhibitor of growth family, member 2
increases expression
EXP
Ketamine results in increased expression of ING2 mRNA
CTD
PMID:20080153
NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482
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Inhba
inhibin subunit beta A
decreases expression
EXP
Ketamine results in decreased expression of INHBA mRNA
CTD
PMID:20080153
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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Ino80c
INO80 complex subunit C
increases expression
EXP
Ketamine results in increased expression of INO80C mRNA
CTD
PMID:20080153
NCBI chr18:15,378,764...15,398,574
Ensembl chr18:15,378,770...15,393,403
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Inpp5d
inositol polyphosphate-5-phosphatase D
increases expression
EXP
Ketamine results in increased expression of INPP5D mRNA
CTD
PMID:20080153
NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
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Inpp5f
inositol polyphosphate-5-phosphatase F
decreases expression
EXP
Ketamine results in decreased expression of INPP5F mRNA
CTD
PMID:20080153
NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276
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Ints3
integrator complex subunit 3
decreases expression
EXP
Ketamine results in decreased expression of INTS3 mRNA
CTD
PMID:20080153
NCBI chr 2:175,859,421...175,911,683
Ensembl chr 2:175,859,440...175,911,709
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Isyna1
inositol-3-phosphate synthase 1
decreases expression
EXP
Ketamine results in decreased expression of ISYNA1 mRNA
CTD
PMID:20080153
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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Itih3
inter-alpha trypsin inhibitor, heavy chain 3
increases expression
EXP
Ketamine results in increased expression of ITIH3 mRNA
CTD
PMID:20080153
NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
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Itm2c
integral membrane protein 2C
increases expression
EXP
Ketamine results in increased expression of ITM2C mRNA
CTD
PMID:20080153
NCBI chr 9:86,545,927...86,559,745
Ensembl chr 9:86,545,921...86,559,742
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Itpka
inositol-trisphosphate 3-kinase A
increases expression
EXP
Ketamine results in increased expression of ITPKA mRNA
CTD
PMID:20080153
NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600
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Ivns1abp
influenza virus NS1A binding protein
decreases expression
EXP
Ketamine results in decreased expression of IVNS1ABP mRNA
CTD
PMID:20080153
NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
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Jade3
jade family PHD finger 3
decreases expression
EXP
Ketamine results in decreased expression of JADE3 mRNA
CTD
PMID:20080153
NCBI chr X:1,668,873...1,848,781
Ensembl chr X:1,669,930...1,845,138
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Jag2
jagged canonical Notch ligand 2
decreases expression
EXP
Ketamine results in decreased expression of JAG2 mRNA
CTD
PMID:20080153
NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818
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Jak2
Janus kinase 2
decreases expression
EXP
Ketamine results in decreased expression of JAK2 mRNA
CTD
PMID:20080153
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Jmjd1c
jumonji domain containing 1C
decreases expression
EXP
Ketamine results in decreased expression of JMJD1C mRNA
CTD
PMID:20080153
NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
EXP
Ketamine results in increased expression of JUN mRNA
CTD
PMID:20080153
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Kazald1
Kazal-type serine peptidase inhibitor domain 1
increases expression
EXP
Ketamine results in increased expression of KAZALD1 mRNA
CTD
PMID:20080153
NCBI chr 1:243,939,596...243,943,060
Ensembl chr 1:243,939,647...243,943,059
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Kazn
kazrin, periplakin interacting protein
increases expression
EXP
Ketamine results in increased expression of KAZN mRNA
CTD
PMID:20080153
NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074
G
Kcnc2
potassium voltage-gated channel subfamily C member 2
decreases expression
EXP
Ketamine results in decreased expression of KCNC2 mRNA
CTD
PMID:20080153
NCBI chr 7:47,700,035...47,883,979
Ensembl chr 7:47,700,288...47,883,968
G
Kcng1
potassium voltage-gated channel modifier subfamily G member 1
decreases expression
EXP
Ketamine results in decreased expression of KCNG1 mRNA
CTD
PMID:20080153
NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
G
Kcnip2
potassium voltage-gated channel interacting protein 2
increases expression
EXP
Ketamine results in increased expression of KCNIP2 mRNA
CTD
PMID:20080153
NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
G
Kcnj14
potassium inwardly-rectifying channel, subfamily J, member 14
decreases expression
EXP
Ketamine results in decreased expression of KCNJ14 mRNA
CTD
PMID:20080153
NCBI chr 1:96,293,159...96,300,810
Ensembl chr 1:96,293,435...96,495,459
G
Kcns3
potassium voltage-gated channel, modifier subfamily S, member 3
decreases expression
EXP
Ketamine results in decreased expression of KCNS3 mRNA
CTD
PMID:20080153
NCBI chr 6:33,808,314...33,865,018
Ensembl chr 6:33,808,216...33,865,125
G
Kiaa0319
KIAA0319 homolog
decreases expression
EXP
Ketamine results in decreased expression of KIAA0319 mRNA
CTD
PMID:20080153
NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653
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Kif11
kinesin family member 11
decreases expression
EXP
Ketamine results in decreased expression of KIF11 mRNA
CTD
PMID:20080153
NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
G
Kif20a
kinesin family member 20A
decreases expression
EXP
Ketamine results in decreased expression of KIF20A mRNA
CTD
PMID:20080153
NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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Klf15
KLF transcription factor 15
increases expression
EXP
Ketamine results in increased expression of KLF15 mRNA
CTD
PMID:20080153
NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
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Klf6
KLF transcription factor 6
decreases expression
EXP
Ketamine results in decreased expression of KLF6 mRNA
CTD
PMID:20080153
NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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Klf9
KLF transcription factor 9
increases expression
EXP
Ketamine results in increased expression of KLF9 mRNA
CTD
PMID:20080153
NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
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Klhdc1
kelch domain containing 1
decreases expression
EXP
Ketamine results in decreased expression of KLHDC1 mRNA
CTD
PMID:20080153
NCBI chr 6:87,670,182...87,765,431
Ensembl chr 6:87,712,772...87,765,424
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Klhdc9
kelch domain containing 9
increases expression
EXP
Ketamine results in increased expression of KLHDC9 mRNA
CTD
PMID:20080153
NCBI chr13:83,790,390...83,794,080
Ensembl chr13:83,790,269...83,793,354
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Klhl24
kelch-like family member 24
decreases expression
EXP
Ketamine results in decreased expression of KLHL24 mRNA
CTD
PMID:20080153
NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636
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Klhl7
kelch-like family member 7
decreases expression
EXP
Ketamine results in decreased expression of KLHL7 mRNA
CTD
PMID:20080153
NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541
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Klhl8
kelch-like family member 8
decreases expression
EXP
Ketamine results in decreased expression of KLHL8 mRNA
CTD
PMID:20080153
NCBI chr14:5,807,795...5,853,325
Ensembl chr14:5,807,907...5,853,294
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Klhl9
kelch-like family member 9
decreases expression
EXP
Ketamine results in decreased expression of KLHL9 mRNA
CTD
PMID:20080153
NCBI chr 5:103,333,747...103,337,931
G
Kmt5a
lysine methyltransferase 5A
decreases expression
EXP
Ketamine results in decreased expression of KMT5A mRNA
CTD
PMID:20080153
NCBI chr12:32,139,353...32,167,777
Ensembl chr12:32,139,178...32,162,711
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Kng1
kininogen 1
multiple interactions
ISO
Ketamine inhibits the reaction [KNG1 protein results in increased expression of OCLN protein]
CTD
PMID:27638051
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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Knstrn
kinetochore-localized astrin/SPAG5 binding protein
decreases expression
EXP
Ketamine results in decreased expression of KNSTRN mRNA
CTD
PMID:20080153
NCBI chr 3:105,800,762...105,820,555
Ensembl chr 3:105,800,954...105,820,715
G
Kpna2
karyopherin subunit alpha 2
decreases expression
EXP
Ketamine results in decreased expression of KPNA2 mRNA
CTD
PMID:20080153
NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150
G
Kpnb1
karyopherin subunit beta 1
decreases expression
EXP
Ketamine results in decreased expression of KPNB1 mRNA
CTD
PMID:20080153
NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605
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Ktn1
kinectin 1
decreases expression
EXP
Ketamine results in decreased expression of KTN1 mRNA
CTD
PMID:20080153
NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578
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Lamb1
laminin subunit beta 1
decreases expression
EXP
Ketamine results in decreased expression of LAMB1 mRNA
CTD
PMID:20080153
NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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Lamp5
lysosomal-associated membrane protein family, member 5
increases expression
EXP
Ketamine results in increased expression of LAMP5 mRNA
CTD
PMID:20080153
NCBI chr 3:123,372,462...123,384,973
Ensembl chr 3:123,372,462...123,384,952
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Laptm4b
lysosomal protein transmembrane 4 beta
increases expression
EXP
Ketamine results in increased expression of LAPTM4B mRNA
CTD
PMID:20080153
NCBI chr 7:65,434,525...65,477,386
Ensembl chr 7:65,434,394...65,477,383
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Laptm5
lysosomal protein transmembrane 5
increases expression
EXP
Ketamine results in increased expression of LAPTM5 mRNA
CTD
PMID:20080153
NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
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Lbp
lipopolysaccharide binding protein
multiple interactions
ISO
Ketamine inhibits the reaction [Lipopolysaccharides binds to LBP protein]
CTD
PMID:19540866
NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
G
Lcn2
lipocalin 2
multiple interactions
ISO
[Ketamine co-treated with Xylazine] results in decreased secretion of LCN2 protein
CTD
PMID:30538007
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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Ldhb
lactate dehydrogenase B
decreases expression
EXP
Ketamine results in decreased expression of LDHB protein
CTD
PMID:18504422
NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
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Leng8
leukocyte receptor cluster member 8
decreases expression
EXP
Ketamine results in decreased expression of LENG8 mRNA
CTD
PMID:20080153
NCBI chr 1:70,040,785...70,052,662
Ensembl chr 1:70,040,785...70,052,488
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Lep
leptin
multiple interactions decreases expression
ISO
LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of BCL2 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased cleavage of CASP3 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of DDIT3 protein]]; LEP protein promotes the reaction [lipoxin A4 methyl ester inhibits the reaction [Ketamine results in increased expression of HSPA5 protein]]; lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of LEP protein]
CTD
PMID:36907275
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lepr
leptin receptor
multiple interactions decreases expression
ISO
lipoxin A4 methyl ester inhibits the reaction [Ketamine results in decreased expression of LEPR protein]
CTD
PMID:36907275
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Lgals3bp
galectin 3 binding protein
increases expression
EXP
Ketamine results in increased expression of LGALS3BP mRNA
CTD
PMID:20080153
NCBI chr10:103,619,912...103,629,251
Ensembl chr10:103,619,908...103,629,256
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Lgi4
leucine-rich repeat LGI family, member 4
increases expression
EXP
Ketamine results in increased expression of LGI4 mRNA
CTD
PMID:20080153
NCBI chr 1:86,294,539...86,305,909
Ensembl chr 1:86,295,074...86,304,874
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Lin7b
lin-7 homolog B, crumbs cell polarity complex component
increases expression
EXP
Ketamine results in increased expression of LIN7B mRNA
CTD
PMID:20080153
NCBI chr 1:95,846,888...95,849,628
Ensembl chr 1:95,846,243...95,849,977
G
Lix1l
limb and CNS expressed 1 like
decreases expression
EXP
Ketamine results in decreased expression of LIX1L mRNA
CTD
PMID:20080153
NCBI chr 2:184,136,018...184,161,918
Ensembl chr 2:184,136,038...184,161,916
G
Lmbr1
limb development membrane protein 1
increases expression
EXP
Ketamine results in increased expression of LMBR1 mRNA
CTD
PMID:20080153
NCBI chr 4:5,974,687...6,146,348
Ensembl chr 4:5,974,750...6,146,368
G
Lmcd1
LIM and cysteine-rich domains 1
increases expression
EXP
Ketamine results in increased expression of LMCD1 mRNA
CTD
PMID:20080153
NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
G
Lrpap1
LDL receptor related protein associated protein 1
increases expression
EXP
Ketamine results in increased expression of LRPAP1 mRNA
CTD
PMID:20080153
NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414
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Lrrc42
leucine rich repeat containing 42
decreases expression
EXP
Ketamine results in decreased expression of LRRC42 mRNA
CTD
PMID:20080153
NCBI chr 5:122,014,678...122,035,792
Ensembl chr 5:122,014,678...122,035,829
G
Lrrc55
leucine rich repeat containing 55
decreases expression
EXP
Ketamine results in decreased expression of LRRC55 mRNA
CTD
PMID:20080153
NCBI chr 3:70,269,908...70,280,651
Ensembl chr 3:70,265,936...70,278,639
G
Lsm10
LSM10, U7 small nuclear RNA associated
decreases expression
EXP
Ketamine results in decreased expression of LSM10 mRNA
CTD
PMID:20080153
NCBI chr 5:138,365,983...138,375,856
Ensembl chr 5:138,373,119...138,377,505
G
Luc7l
LUC7-like
decreases expression
EXP
Ketamine results in decreased expression of LUC7L mRNA
CTD
PMID:20080153
NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112
G
Lypd3
Ly6/Plaur domain containing 3
decreases expression
EXP
Ketamine results in decreased expression of LYPD3 mRNA
CTD
PMID:20080153
NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901
G
Mal
mal, T-cell differentiation protein
increases expression
EXP
Ketamine results in increased expression of MAL mRNA
CTD
PMID:20080153
NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
G
Man2b1
mannosidase, alpha, class 2B, member 1
increases expression
EXP
Ketamine results in increased expression of MAN2B1 mRNA
CTD
PMID:20080153
NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
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Manf
mesencephalic astrocyte-derived neurotrophic factor
decreases expression
EXP ISO
Ketamine results in decreased expression of MANF mRNA
CTD
PMID:20080153 PMID:35728656
NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438
G
Map1b
microtubule-associated protein 1B
decreases expression
EXP
Ketamine results in decreased expression of MAP1B mRNA
CTD
PMID:20080153
NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317
G
Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
ISO
Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP2K1 protein]
CTD
PMID:19540866
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Map2k2
mitogen activated protein kinase kinase 2
multiple interactions
ISO
Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAP2K2 protein]
CTD
PMID:19540866
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
G
Map6
microtubule-associated protein 6
increases expression
EXP
Ketamine results in increased expression of MAP6 mRNA
CTD
PMID:20080153
NCBI chr 1:153,568,020...153,634,415
Ensembl chr 1:153,568,368...153,634,414
G
Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
CTD
PMID:19540866
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
Ketamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
CTD
PMID:19540866
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Mapk7
mitogen-activated protein kinase 7
decreases expression
EXP
Ketamine results in decreased expression of MAPK7 mRNA
CTD
PMID:20080153
NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267
G
Mapt
microtubule-associated protein tau
increases phosphorylation multiple interactions
ISO
Ketamine results in increased phosphorylation of MAPT protein MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA1 protein]; MAPT protein affects the reaction [Ketamine results in decreased expression of GRIA2 protein]
CTD
PMID:20093173 PMID:31470060
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
G
Marf1
meiosis regulator and mRNA stability factor 1
decreases expression
EXP
Ketamine results in decreased expression of MARF1 mRNA
CTD
PMID:20080153
NCBI chr10:888,053...932,760
Ensembl chr10:888,076...932,753
G
Mas1
MAS1 proto-oncogene, G protein-coupled receptor
decreases expression
EXP
Ketamine results in decreased expression of MAS1 mRNA
CTD
PMID:20080153
NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
G
Matk
megakaryocyte-associated tyrosine kinase
increases expression
EXP
Ketamine results in increased expression of MATK mRNA
CTD
PMID:20080153
NCBI chr 7:8,456,990...8,465,947
Ensembl chr 7:8,456,998...8,462,022
G
Mavs
mitochondrial antiviral signaling protein
decreases expression
EXP
Ketamine results in decreased expression of MAVS mRNA
CTD
PMID:20080153
NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
G
Mbp
myelin basic protein
increases expression
EXP
Ketamine results in increased expression of MBP mRNA
CTD
PMID:20080153
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
G
Mcm3
minichromosome maintenance complex component 3
decreases expression
EXP
Ketamine results in decreased expression of MCM3 mRNA
CTD
PMID:20080153
NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314
G
Mcu
mitochondrial calcium uniporter
decreases expression
EXP
Ketamine results in decreased expression of MCU mRNA
CTD
PMID:20080153
NCBI chr20:27,417,529...27,580,110
Ensembl chr20:27,417,526...27,580,110
G
Mettl16
methyltransferase 16, RNA N6-adenosine
decreases expression
EXP
Ketamine results in decreased expression of METTL16 mRNA
CTD
PMID:20080153
NCBI chr10:59,640,915...59,697,291
Ensembl chr10:59,640,972...59,687,061
G
Mettl25b
methyltransferase like 25B
increases expression
EXP
Ketamine results in increased expression of METTL25B mRNA
CTD
PMID:20080153
NCBI chr 2:173,388,625...173,397,279
Ensembl chr 2:173,388,625...173,397,279
G
Mettl3
methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
decreases expression
EXP
Ketamine results in decreased expression of METTL3 mRNA
CTD
PMID:20080153
NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041
G
Mfsd2a
MFSD2 lysolipid transporter A, lysophospholipid
increases expression
EXP
Ketamine results in increased expression of MFSD2A mRNA
CTD
PMID:20080153
NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
G
Mgst2
microsomal glutathione S-transferase 2
increases expression
EXP
Ketamine results in increased expression of MGST2 mRNA
CTD
PMID:20080153
NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
G
Mgst3l1
microsomal glutathione S-transferase 3 like 1
increases expression
EXP
Ketamine results in increased expression of MGST3L1 mRNA
CTD
PMID:20080153
NCBI chr14:19,525,509...19,526,128
Ensembl chr14:19,525,558...19,526,016
G
Mib1
MIB E3 ubiquitin protein ligase 1
increases expression
EXP
Ketamine results in increased expression of MIB1 mRNA
CTD
PMID:20080153
NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689
G
Mical1
microtubule associated monooxygenase, calponin and LIM domain containing 1
decreases expression
EXP
Ketamine results in decreased expression of MICAL1 mRNA
CTD
PMID:20080153
NCBI chr20:44,974,137...44,986,089
Ensembl chr20:44,974,138...44,986,089
G
Mif4gd
MIF4G domain containing
increases expression
EXP
Ketamine results in increased expression of MIF4GD mRNA
CTD
PMID:20080153
NCBI chr10:100,847,168...100,852,166
G
Mis12
MIS12 kinetochore complex component
decreases expression
EXP
Ketamine results in decreased expression of MIS12 mRNA
CTD
PMID:20080153
NCBI chr10:55,739,741...55,747,915
Ensembl chr10:55,739,564...55,751,068
G
Mis18a
MIS18 kinetochore protein A
decreases expression
EXP
Ketamine results in decreased expression of MIS18A mRNA
CTD
PMID:20080153
NCBI chr11:29,968,030...29,981,058
Ensembl chr11:29,967,701...29,981,062
G
Mki67
marker of proliferation Ki-67
increases expression
ISO
Ketamine results in increased expression of MKI67 protein
CTD
PMID:19919587
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
G
Mkks
MKKS centrosomal shuttling protein
decreases expression
EXP
Ketamine results in decreased expression of MKKS mRNA
CTD
PMID:20080153
NCBI chr 3:124,201,877...124,221,142
Ensembl chr 3:124,201,877...124,220,162
G
Mllt3
MLLT3, super elongation complex subunit
decreases expression
EXP
Ketamine results in decreased expression of MLLT3 mRNA
CTD
PMID:20080153
NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361
G
Mmd2
monocyte to macrophage differentiation-associated 2
increases expression
EXP
Ketamine results in increased expression of MMD2 mRNA
CTD
PMID:20080153
NCBI chr12:11,962,733...12,009,776
Ensembl chr12:11,962,757...12,009,773
G
Mmp14
matrix metallopeptidase 14
decreases expression
EXP
Ketamine results in decreased expression of MMP14 mRNA
CTD
PMID:20080153
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
G
Mog
myelin oligodendrocyte glycoprotein
increases expression
EXP
Ketamine results in increased expression of MOG mRNA
CTD
PMID:20080153
NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474
G
Mon1a
MON1 homolog A, secretory trafficking associated
decreases expression
EXP
Ketamine results in decreased expression of MON1A mRNA
CTD
PMID:20080153
NCBI chr 8:108,574,272...108,593,163
Ensembl chr 8:108,574,388...108,593,156
G
Morn2
MORN repeat containing 2
increases expression
EXP
Ketamine results in increased expression of MORN2 mRNA
CTD
PMID:20080153
NCBI chr 6:14,718,799...14,725,281
G
Mras
muscle RAS oncogene homolog
increases expression
EXP
Ketamine results in increased expression of MRAS mRNA
CTD
PMID:20080153
NCBI chr 8:99,944,036...100,006,771
Ensembl chr 8:99,944,036...99,996,408
G
Mrpl18
mitochondrial ribosomal protein L18
decreases expression
EXP
Ketamine results in decreased expression of MRPL18 mRNA
CTD
PMID:20080153
NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987
G
Mrpl50
mitochondrial ribosomal protein L50
decreases expression
EXP
Ketamine results in decreased expression of MRPL50 mRNA
CTD
PMID:20080153
NCBI chr 5:63,867,437...63,872,591
G
Mrps15
mitochondrial ribosomal protein S15
increases expression
EXP
Ketamine results in increased expression of MRPS15 mRNA
CTD
PMID:20080153
NCBI chr 5:138,321,610...138,332,205
Ensembl chr 5:138,321,593...138,332,205
G
Ms4a6a
membrane spanning 4-domains A6A
increases expression
EXP
Ketamine results in increased expression of MS4A6A mRNA
CTD
PMID:20080153
NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758
G
Msantd3
Myb/SANT DNA binding domain containing 3
increases expression
EXP
Ketamine results in increased expression of MSANTD3 mRNA
CTD
PMID:20080153
NCBI chr 5:62,866,022...62,892,444
Ensembl chr 5:62,866,022...62,888,859
G
Msmo1
methylsterol monooxygenase 1
decreases expression
EXP
Ketamine results in decreased expression of MSMO1 mRNA
CTD
PMID:20080153
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
G
Mt1
metallothionein 1
increases expression
EXP
Ketamine results in increased expression of MT1A mRNA
CTD
PMID:20080153
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
G
Mtcl3
MTCL family member 3
decreases expression
EXP
Ketamine results in decreased expression of MTCL3 mRNA
CTD
PMID:20080153
NCBI chr 1:28,629,036...28,701,416
Ensembl chr 1:28,620,293...28,701,796
G
Mterf2
mitochondrial transcription termination factor 2
decreases expression
EXP
Ketamine results in decreased expression of MTERF2 mRNA
CTD
PMID:20080153
NCBI chr 7:18,598,202...18,608,278
Ensembl chr 7:18,598,103...18,620,684
G
Mtg2
mitochondrial ribosome-associated GTPase 2
decreases expression
EXP
Ketamine results in decreased expression of MTG2 mRNA
CTD
PMID:20080153
NCBI chr 3:167,165,542...167,181,358
Ensembl chr 3:167,165,982...167,181,358
G
Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
EXP
Ketamine results in decreased expression of MYC mRNA
CTD
PMID:20080153
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
G
Mycn
MYCN proto-oncogene, bHLH transcription factor
decreases expression
EXP
Ketamine results in decreased expression of MYCN mRNA
CTD
PMID:20080153
NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
G
Myo19
myosin XIX
decreases expression
EXP
Ketamine results in decreased expression of MYO19 mRNA
CTD
PMID:20080153
NCBI chr10:69,753,082...69,782,450
Ensembl chr10:69,753,068...69,782,450
G
Naa35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
decreases expression
EXP
Ketamine results in decreased expression of MAK10 mRNA
CTD
PMID:20080153
NCBI chr17:5,034,360...5,086,456
Ensembl chr17:5,034,356...5,086,386
G
Nab1
Ngfi-A binding protein 1
decreases expression
EXP
Ketamine results in decreased expression of NAB1 mRNA
CTD
PMID:20080153
NCBI chr 9:49,053,579...49,093,078
Ensembl chr 9:49,053,758...49,092,098
G
Nabp1
nucleic acid binding protein 1
decreases expression
EXP
Ketamine results in decreased expression of NABP1 mRNA
CTD
PMID:20080153
NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107
G
Nav3
neuron navigator 3
decreases expression
EXP
Ketamine results in decreased expression of NAV3 mRNA
CTD
PMID:20080153
NCBI chr 7:45,052,206...45,840,471
Ensembl chr 7:45,054,296...45,840,698
G
Ncdn
neurochondrin
increases expression
EXP
Ketamine results in increased expression of NCDN mRNA
CTD
PMID:20080153
NCBI chr 5:139,037,807...139,047,645
Ensembl chr 5:139,037,819...139,047,568
G
Nckap1l
NCK associated protein 1 like
decreases expression multiple interactions
EXP
Ketamine results in decreased expression of NCKAP1L mRNA Cannabidiol inhibits the reaction [Ketamine results in decreased expression of NCKAP1L mRNA]
CTD
PMID:31823199
NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
G
Ndrg2
NDRG family member 2
increases expression
EXP
Ketamine results in increased expression of NDRG2 mRNA
CTD
PMID:20080153
NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
G
Ndufs1
NADH:ubiquinone oxidoreductase core subunit S1
decreases expression
EXP
Ketamine results in decreased expression of NDUFS1 protein
CTD
PMID:18504422
NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
G
Nectin3
nectin cell adhesion molecule 3
decreases expression
EXP
Ketamine results in decreased expression of NECTIN3 mRNA
CTD
PMID:20080153
NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519
G
Nefl
neurofilament light chain
decreases expression increases expression
EXP
Ketamine results in decreased expression of NEFL protein Ketamine results in increased expression of NEFL mRNA
CTD
PMID:18504422 PMID:20080153
NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
G
Nes
nestin
decreases expression
EXP
Ketamine results in decreased expression of NES mRNA
CTD
PMID:20080153
NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
G
Neurod6
neuronal differentiation 6
decreases expression
EXP
Ketamine results in decreased expression of NEUROD6 mRNA
CTD
PMID:20080153
NCBI chr 4:84,846,659...84,849,905
Ensembl chr 4:84,846,231...84,849,999
G
Nfe2l2
NFE2 like bZIP transcription factor 2
decreases expression multiple interactions
EXP
Ketamine results in decreased expression of NFE2L2 mRNA; Ketamine results in decreased expression of NFE2L2 protein; Ketamine results in decreased expression of NFE2L2 protein modified form Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein modified form]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NFE2L2 protein]
CTD
PMID:36305173
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
G
Nfe2l3
NFE2 like bZIP transcription factor 3
decreases expression
EXP
Ketamine results in decreased expression of NFE2L3 mRNA
CTD
PMID:20080153
NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629
G
Nfil3
nuclear factor, interleukin 3 regulated
decreases expression
EXP
Ketamine results in decreased expression of NFIL3 mRNA
CTD
PMID:20080153
NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
G
Nfkbia
NFKB inhibitor alpha
increases expression increases phosphorylation multiple interactions
EXP
Ketamine results in increased expression of NFKBIA mRNA Ketamine results in increased phosphorylation of NFKBIA protein TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of NFKBIA protein]
CTD
PMID:20080153 PMID:33536391
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Ngf
nerve growth factor
multiple interactions
EXP
Ketamine inhibits the reaction [Pilocarpine results in increased expression of NGF mRNA]
CTD
PMID:8635431
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
G
Nif3l1
NGG1 interacting factor 3 like 1
decreases expression
EXP
Ketamine results in decreased expression of NIF3L1 mRNA
CTD
PMID:20080153
NCBI chr 9:59,980,101...60,001,490
Ensembl chr 9:59,979,799...60,000,131
G
Nkiras1
NFKB inhibitor interacting Ras-like 1
increases expression
EXP
Ketamine results in increased expression of NKIRAS1 mRNA
CTD
PMID:20080153
NCBI chr15:7,493,531...7,503,758
Ensembl chr15:7,493,531...7,503,854
G
Nkx6-2
NK6 homeobox 2
increases expression
EXP
Ketamine results in increased expression of NKX6-2 mRNA
CTD
PMID:20080153
NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515
G
Nln
neurolysin
decreases expression
EXP
Ketamine results in decreased expression of NLN mRNA
CTD
PMID:20080153
NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914
G
Nmb
neuromedin B
increases expression
EXP
Ketamine results in increased expression of NMB mRNA
CTD
PMID:20080153
NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190
G
Nme6
NME/NM23 nucleoside diphosphate kinase 6
decreases expression
EXP
Ketamine results in decreased expression of NME6 mRNA
CTD
PMID:20080153
NCBI chr 8:109,832,085...109,839,301
Ensembl chr 8:109,832,589...109,839,301
G
Nnt
nicotinamide nucleotide transhydrogenase
decreases expression
EXP
Ketamine results in decreased expression of NNT mRNA
CTD
PMID:20080153
NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
G
Nol4
nucleolar protein 4
decreases expression
EXP
Ketamine results in decreased expression of NOL4 mRNA
CTD
PMID:20080153
NCBI chr18:13,932,499...14,294,873
Ensembl chr18:13,932,510...14,296,286
G
Nova2
NOVA alternative splicing regulator 2
decreases expression
EXP
Ketamine results in decreased expression of NOVA2 mRNA
CTD
PMID:20080153
NCBI chr 1:78,572,253...78,613,703
Ensembl chr 1:78,572,279...78,608,021
G
Npm3
nucleophosmin/nucleoplasmin, 3
decreases expression
EXP
Ketamine results in decreased expression of NPM3 mRNA
CTD
PMID:20080153
NCBI chr 1:244,595,638...244,597,623
Ensembl chr 1:244,595,644...244,597,591
G
Nppc
natriuretic peptide C
decreases expression
EXP
Ketamine results in decreased expression of NPPC mRNA
CTD
PMID:20080153
NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
G
Npy
neuropeptide Y
increases response to substance
ISO
NPY protein results in increased susceptibility to Ketamine
CTD
PMID:11454027
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
G
Npy1r
neuropeptide Y receptor Y1
decreases expression
EXP
Ketamine results in decreased expression of NPY1R mRNA
CTD
PMID:20080153
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
G
Nqo1
NAD(P)H quinone dehydrogenase 1
decreases expression multiple interactions
EXP
Ketamine results in decreased expression of NQO1 mRNA; Ketamine results in decreased expression of NQO1 protein Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 mRNA]; Curcumin inhibits the reaction [Ketamine results in decreased expression of NQO1 protein]
CTD
PMID:36305173
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
G
Nr1d1
nuclear receptor subfamily 1, group D, member 1
increases expression
EXP
Ketamine results in increased expression of NR1D1 mRNA
CTD
PMID:20080153
NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
G
Nr4a2
nuclear receptor subfamily 4, group A, member 2
decreases expression
EXP
Ketamine results in decreased expression of NR4A2 mRNA
CTD
PMID:20080153
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
G
Nr4a3
nuclear receptor subfamily 4, group A, member 3
decreases expression
EXP
Ketamine results in decreased expression of NR4A3 mRNA
CTD
PMID:20080153
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
G
Nradd
neurotrophin receptor associated death domain
decreases expression
EXP
Ketamine results in decreased expression of NRADD mRNA
CTD
PMID:20080153
NCBI chr 8:110,599,667...110,603,068
Ensembl chr 8:110,599,667...110,603,149
G
Nrde2
NRDE-2, necessary for RNA interference, domain containing
increases expression
EXP
Ketamine results in increased expression of NRDE2 mRNA
CTD
PMID:20080153
NCBI chr 6:119,405,103...119,446,861
Ensembl chr 6:119,404,334...119,448,915
G
Nrep
neuronal regeneration related protein
decreases expression
EXP
Ketamine results in decreased expression of NREP mRNA
CTD
PMID:20080153
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
G
Nrg1
neuregulin 1
decreases expression
ISO
Ketamine results in decreased expression of NRG1 mRNA
CTD
PMID:20000043
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
G
Nrgn
neurogranin
increases expression
EXP
Ketamine results in increased expression of NRGN mRNA
CTD
PMID:20080153
NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516
G
Nrip3
nuclear receptor interacting protein 3
decreases expression
EXP
Ketamine results in decreased expression of NRIP3 mRNA
CTD
PMID:20080153
NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600
G
Nsf
N-ethylmaleimide sensitive factor, vesicle fusing ATPase
increases expression
EXP
Ketamine results in increased expression of NSF mRNA
CTD
PMID:20080153
NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386
G
Nsmce2
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase
decreases expression
EXP
Ketamine results in decreased expression of NSMCE2 mRNA
CTD
PMID:20080153
NCBI chr 7:90,936,112...91,173,435
Ensembl chr 7:90,936,112...91,164,899
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Nt5c2
5'-nucleotidase, cytosolic II
increases expression
EXP
Ketamine results in increased expression of NT5C2 mRNA
CTD
PMID:20080153
NCBI chr 1:245,770,993...245,896,925
Ensembl chr 1:245,772,277...245,897,913
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Ntf3
neurotrophin 3
decreases expression
EXP
Ketamine results in decreased expression of NTF3 mRNA
CTD
PMID:20080153
NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
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Ntrk1
neurotrophic receptor tyrosine kinase 1
increases expression
EXP
Ketamine results in increased expression of NTRK1 mRNA
CTD
PMID:20080153
NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
G
Ntrk2
neurotrophic receptor tyrosine kinase 2
multiple interactions
EXP ISO
Ketamine inhibits the reaction [Pilocarpine results in increased expression of NTRK2 mRNA] Ketamine inhibits the reaction [NTRK2 protein binds to AP2M1 protein]
CTD
PMID:8635431 PMID:31631060
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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Nudt6
nudix hydrolase 6
increases expression
EXP
Ketamine results in increased expression of NUDT6 mRNA
CTD
PMID:20080153
NCBI chr 2:120,289,908...120,306,197
Ensembl chr 2:120,290,847...120,306,230
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Nup205
nucleoporin 205
decreases expression
EXP
Ketamine results in decreased expression of NUP205 mRNA
CTD
PMID:20080153
NCBI chr 4:63,854,934...63,920,852
Ensembl chr 4:63,854,783...63,920,844
G
Nup35
nucleoporin 35
decreases expression
EXP
Ketamine results in decreased expression of NUP35 mRNA
CTD
PMID:20080153
NCBI chr 3:65,555,203...65,594,488
Ensembl chr 3:65,558,968...65,585,130
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Nup42
nucleoporin 42
increases expression
EXP
Ketamine results in increased expression of NUP42 mRNA
CTD
PMID:20080153
NCBI chr 4:10,985,554...11,002,591
Ensembl chr 4:10,985,554...11,002,591
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Nup58
nucleoporin 58
decreases expression
EXP
Ketamine results in decreased expression of NUP58 mRNA
CTD
PMID:20080153
NCBI chr15:34,358,170...34,407,160
Ensembl chr15:34,358,277...34,407,060
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Nusap1
nucleolar and spindle associated protein 1
decreases expression
EXP
Ketamine results in decreased expression of NUSAP1 mRNA
CTD
PMID:20080153
NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624
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Ocln
occludin
multiple interactions
ISO
Ketamine inhibits the reaction [KNG1 protein results in increased expression of OCLN protein]
CTD
PMID:27638051
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
G
Oplah
5-oxoprolinase (ATP-hydrolysing)
increases expression
EXP
Ketamine results in increased expression of OPLAH mRNA
CTD
PMID:20080153
NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297
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Orc4
origin recognition complex, subunit 4
increases expression
EXP
Ketamine results in increased expression of ORC4 mRNA
CTD
PMID:20080153
NCBI chr 3:33,290,844...33,334,022
Ensembl chr 3:33,294,355...33,333,824
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Ormdl3
ORMDL sphingolipid biosynthesis regulator 3
increases expression
EXP
Ketamine results in increased expression of ORMDL3 mRNA
CTD
PMID:20080153
NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620
G
Oxsr1
oxidative stress responsive kinase 1
decreases expression
EXP
Ketamine results in decreased expression of OXSR1 mRNA
CTD
PMID:20080153
NCBI chr 8:118,972,754...119,062,102
Ensembl chr 8:118,972,754...119,062,027
G
P2rx6
purinergic receptor P2X 6
increases expression
EXP
Ketamine results in increased expression of P2RX6 mRNA
CTD
PMID:20080153
NCBI chr11:83,439,922...83,450,449
Ensembl chr11:83,439,924...83,450,481
G
P4ha1
prolyl 4-hydroxylase subunit alpha 1
decreases expression
EXP
Ketamine results in decreased expression of P4HA1 mRNA
CTD
PMID:20080153
NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
G
P4htm
prolyl 4-hydroxylase, transmembrane
increases expression
EXP
Ketamine results in increased expression of P4HTM mRNA
CTD
PMID:20080153
NCBI chr 8:109,274,629...109,292,802
Ensembl chr 8:109,274,626...109,292,473
G
Pak5
p21 (RAC1) activated kinase 5
decreases expression
EXP
Ketamine results in decreased expression of PAK5 mRNA
CTD
PMID:20080153
NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930
G
Pank1
pantothenate kinase 1
decreases expression
EXP
Ketamine results in decreased expression of PANK1 mRNA
CTD
PMID:20080153
NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
G
Papola
poly (A) polymerase alpha
decreases expression
EXP
Ketamine results in decreased expression of PAPOLA mRNA
CTD
PMID:20080153
NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
G
Pard6g
par-6 family cell polarity regulator gamma
decreases expression
EXP
Ketamine results in decreased expression of PARD6G mRNA
CTD
PMID:20080153
NCBI chr18:73,497,992...73,565,048
Ensembl chr18:73,498,021...73,565,029
G
Pbk
PDZ binding kinase
decreases expression
EXP
Ketamine results in decreased expression of PBK mRNA
CTD
PMID:20080153
NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
G
Pbx3
PBX homeobox 3
decreases expression
EXP
Ketamine results in decreased expression of PBX3 mRNA
CTD
PMID:20080153
NCBI chr 3:17,488,691...17,682,412
Ensembl chr 3:17,488,693...17,682,791
G
Pcgf6
polycomb group ring finger 6
decreases expression
EXP
Ketamine results in decreased expression of PCGF6 mRNA
CTD
PMID:20080153
NCBI chr 1:245,925,354...245,944,964
Ensembl chr 1:245,925,360...245,944,914
G
Pclaf
PCNA clamp associated factor
decreases expression
EXP
Ketamine results in decreased expression of PCLAF mRNA
CTD
PMID:20080153
NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994 Ensembl chr 8:66,420,587...66,432,994
G
Pcsk2
proprotein convertase subtilisin/kexin type 2
increases expression
EXP
Ketamine results in increased expression of PCSK2 mRNA
CTD
PMID:20080153
NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127
G
Pde12
phosphodiesterase 12
increases expression
EXP
Ketamine results in increased expression of PDE12 mRNA
CTD
PMID:20080153
NCBI chr16:1,920,062...1,925,638
Ensembl chr16:1,915,386...1,925,887
G
Pdia2
protein disulfide isomerase family A, member 2
decreases expression
EXP
Ketamine results in decreased expression of PDIA2 mRNA
CTD
PMID:20080153
NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931
G
Pdia4
protein disulfide isomerase family A, member 4
decreases expression
EXP
Ketamine results in decreased expression of PDIA4 mRNA
CTD
PMID:20080153
NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
G
Pdia5
protein disulfide isomerase family A, member 5
decreases expression
EXP
Ketamine results in decreased expression of PDIA5 mRNA
CTD
PMID:20080153
NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084
G
Pdia6
protein disulfide isomerase family A, member 6
decreases expression
EXP
Ketamine results in decreased expression of PDIA6 mRNA
CTD
PMID:20080153
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
G
Pdik1l
PDLIM1 interacting kinase 1 like
decreases expression
EXP
Ketamine results in decreased expression of PDIK1L mRNA
CTD
PMID:20080153
NCBI chr 5:146,495,115...146,507,363
Ensembl chr 5:146,495,115...146,506,835
G
Pdk2
pyruvate dehydrogenase kinase 2
increases expression
EXP
Ketamine results in increased expression of PDK2 mRNA
CTD
PMID:20080153
NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085
G
Pdlim7
PDZ and LIM domain 7
decreases expression
EXP
Ketamine results in decreased expression of PDLIM7 mRNA
CTD
PMID:20080153
NCBI chr17:9,124,565...9,139,814
Ensembl chr17:9,124,649...9,139,811
G
Pdp2
pyruvate dehydrogenase phosphatase catalytic subunit 2
decreases expression
EXP
Ketamine results in decreased expression of PDP2 mRNA
CTD
PMID:20080153
NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074
G
Pdrg1
p53 and DNA damage regulated 1
increases expression
EXP
Ketamine results in increased expression of PDRG1 mRNA
CTD
PMID:20080153
NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858 Ensembl chr 3:141,476,501...141,483,858
G
Pef1
penta-EF hand domain containing 1
increases expression
EXP
Ketamine results in increased expression of PEF1 mRNA
CTD
PMID:20080153
NCBI chr 5:142,451,791...142,475,061
Ensembl chr 5:142,451,778...142,475,067
G
Per1
period circadian regulator 1
increases expression
EXP
Ketamine results in increased expression of PER1 mRNA
CTD
PMID:20080153
NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
G
Pgpep1
pyroglutamyl-peptidase I
decreases expression
EXP
Ketamine results in decreased expression of PGPEP1 mRNA
CTD
PMID:20080153
NCBI chr16:18,770,563...18,782,968
Ensembl chr16:18,771,021...18,783,478
G
Phactr3
phosphatase and actin regulator 3
decreases expression
EXP
Ketamine results in decreased expression of PHACTR3 mRNA
CTD
PMID:20080153
NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:165,205,255...165,423,153
G
Phb1
prohibitin 1
increases expression
EXP
Ketamine results in increased expression of PHB1 protein
CTD
PMID:18504422
NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
G
Phf13
PHD finger protein 13
decreases expression
EXP
Ketamine results in decreased expression of PHF13 mRNA
CTD
PMID:20080153
NCBI chr 5:162,494,574...162,501,350
Ensembl chr 5:162,494,573...162,501,350
G
Phf14
PHD finger protein 14
decreases expression
EXP
Ketamine results in decreased expression of PHF14 mRNA
CTD
PMID:20080153
NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885
G
Phrf1
PHD and ring finger domains 1
decreases expression
EXP
Ketamine results in decreased expression of PHRF1 mRNA
CTD
PMID:20080153
NCBI chr 1:196,333,663...196,366,901
Ensembl chr 1:196,333,903...196,366,892
G
Phyhip
phytanoyl-CoA 2-hydroxylase interacting protein
increases expression
EXP
Ketamine results in increased expression of PHYHIP mRNA
CTD
PMID:20080153
NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221
G
Pibf1
progesterone immunomodulatory binding factor 1
decreases expression
EXP
Ketamine results in decreased expression of PIBF1 mRNA
CTD
PMID:20080153
NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
G
Pigl
phosphatidylinositol glycan anchor biosynthesis, class L
decreases expression
EXP
Ketamine results in decreased expression of PIGL mRNA
CTD
PMID:20080153
NCBI chr10:47,142,160...47,199,892
Ensembl chr10:47,141,780...47,200,145
G
Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
decreases expression
EXP
Ketamine results in decreased expression of PIK3AP1 mRNA
CTD
PMID:20080153
NCBI chr 1:240,090,854...240,245,007
Ensembl chr 1:240,093,065...240,204,828
G
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
increases expression
EXP
Ketamine results in increased expression of PIK3IP1 mRNA
CTD
PMID:20080153
NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608
G
Pip4k2a
phosphatidylinositol-5-phosphate 4-kinase type 2 alpha
decreases expression
EXP
Ketamine results in decreased expression of PIP4K2A mRNA
CTD
PMID:20080153
NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029
G
Pkd1
polycystin 1, transient receptor potential channel interacting
increases expression
EXP
Ketamine results in increased expression of PKD1 mRNA
CTD
PMID:20080153
NCBI chr10:13,573,779...13,621,138
Ensembl chr10:13,573,021...13,621,128
G
Plaat3
phospholipase A and acyltransferase 3
increases expression
EXP
Ketamine results in increased expression of PLAAT3 mRNA
CTD
PMID:20080153
NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667
G
Plat
plasminogen activator, tissue type
increases expression
EXP
Ketamine results in increased expression of PLAT mRNA
CTD
PMID:20080153
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
G
Plcd4
phospholipase C, delta 4
increases expression
EXP
Ketamine results in increased expression of PLCD4 mRNA
CTD
PMID:20080153
NCBI chr 9:76,115,523...76,158,602
Ensembl chr 9:76,117,168...76,142,453
G
Plcl1
phospholipase C-like 1
decreases expression
EXP
Ketamine results in decreased expression of PLCL1 mRNA
CTD
PMID:20080153
NCBI chr 9:56,901,573...57,238,782
Ensembl chr 9:56,901,534...57,238,782
G
Plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
decreases expression
EXP
Ketamine results in decreased expression of PLCXD3 mRNA
CTD
PMID:20080153
NCBI chr 2:53,567,022...53,746,384
Ensembl chr 2:53,567,022...53,746,384
G
Pld4
phospholipase D family, member 4
increases expression
EXP
Ketamine results in increased expression of PLD4 mRNA
CTD
PMID:20080153
NCBI chr 6:131,818,860...131,827,457
Ensembl chr 6:131,818,860...131,826,376
G
Plekhb1
pleckstrin homology domain containing B1
increases expression
EXP
Ketamine results in increased expression of PLEKHB1 mRNA
CTD
PMID:20080153
NCBI chr 1:154,998,798...155,013,094
Ensembl chr 1:154,998,800...155,016,142
G
Plekhf2
pleckstrin homology and FYVE domain containing 2
decreases expression
EXP
Ketamine results in decreased expression of PLEKHF2 mRNA
CTD
PMID:20080153
NCBI chr 5:24,091,077...24,106,758
Ensembl chr 5:24,090,688...24,106,601
G
Plgrkt
plasminogen receptor with a C-terminal lysine
decreases expression
EXP
Ketamine results in decreased expression of PLGRKT mRNA
CTD
PMID:20080153
NCBI chr 1:227,099,005...227,111,277
Ensembl chr 1:227,099,015...227,111,194
G
Plp1
proteolipid protein 1
increases expression
EXP
Ketamine results in increased expression of PLP1 mRNA
CTD
PMID:20080153
NCBI chr X:100,184,039...100,201,035
Ensembl chr X:100,185,767...100,201,032
G
Plppr1
phospholipid phosphatase related 1
decreases expression
EXP
Ketamine results in decreased expression of PLPPR1 mRNA
CTD
PMID:20080153
NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
G
Plvap
plasmalemma vesicle associated protein
increases expression
EXP
Ketamine results in increased expression of PLVAP mRNA
CTD
PMID:20080153
NCBI chr16:18,184,985...18,197,301
Ensembl chr16:18,184,975...18,197,301
G
Plxna2
plexin A2
decreases expression
EXP
Ketamine results in decreased expression of PLXNA2 mRNA
CTD
PMID:20080153
NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979
G
Pmpca
peptidase, mitochondrial processing subunit alpha
increases expression
EXP
Ketamine results in increased expression of PMPCA mRNA
CTD
PMID:20080153
NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844
G
Pnp
purine nucleoside phosphorylase
decreases expression
EXP
Ketamine results in decreased expression of PNP mRNA
CTD
PMID:20080153
NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986
G
Pnpla2
patatin-like phospholipase domain containing 2
increases expression
EXP
Ketamine results in increased expression of PNPLA2 mRNA
CTD
PMID:20080153
NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805
G
Pofut2
protein O-fucosyltransferase 2
decreases expression
EXP
Ketamine results in decreased expression of POFUT2 mRNA
CTD
PMID:20080153
NCBI chr20:11,367,073...11,377,788
Ensembl chr20:11,367,096...11,377,743
G
Pola1
DNA polymerase alpha 1, catalytic subunit
decreases expression
EXP
Ketamine results in decreased expression of POLA1 mRNA
CTD
PMID:20080153
NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536
G
Pold1
DNA polymerase delta 1, catalytic subunit
decreases expression
EXP
Ketamine results in decreased expression of POLD1 mRNA
CTD
PMID:20080153
NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
G
Pole2
DNA polymerase epsilon 2, accessory subunit
decreases expression
EXP
Ketamine results in decreased expression of POLE2 mRNA
CTD
PMID:20080153
NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
G
Polg
DNA polymerase gamma, catalytic subunit
decreases expression
EXP
Ketamine results in decreased expression of POLG mRNA
CTD
PMID:20080153
NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
G
Polr2f
RNA polymerase II, I and III subunit F
increases expression
EXP
Ketamine results in increased expression of POLR2F mRNA
CTD
PMID:20080153
NCBI chr 7:110,712,528...110,724,234
Ensembl chr 7:110,712,572...110,724,234
G
Polr3f
RNA polymerase III subunit F
increases expression
EXP
Ketamine results in increased expression of POLR3F mRNA
CTD
PMID:20080153
NCBI chr 3:131,908,466...131,924,838
Ensembl chr 3:131,908,466...131,924,837
G
Polr3h
RNA polymerase III subunit H
decreases expression
EXP
Ketamine results in decreased expression of POLR3H mRNA
CTD
PMID:20080153
NCBI chr 7:113,429,434...113,439,743
Ensembl chr 7:113,429,451...113,439,778
G
Pomt2
protein-O-mannosyltransferase 2
decreases expression
EXP
Ketamine results in decreased expression of POMT2 mRNA
CTD
PMID:20080153
NCBI chr 6:106,755,462...106,794,849
Ensembl chr 6:106,755,462...106,794,849
G
Potem
POTE ankyrin domain family member M
increases expression
EXP
Ketamine results in increased expression of POTEM mRNA
CTD
PMID:20080153
NCBI chr16:20,193,646...20,311,924
Ensembl chr16:19,949,230...19,976,541
G
Pou3f2
POU class 3 homeobox 2
decreases expression
EXP
Ketamine results in decreased expression of POU3F2 mRNA
CTD
PMID:20080153
NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838
G
Ppp1r14b
protein phosphatase 1, regulatory (inhibitor) subunit 14B
decreases expression
EXP
Ketamine results in decreased expression of PPP1R14B mRNA
CTD
PMID:20080153
NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319
G
Ppp1r18
protein phosphatase 1, regulatory subunit 18
decreases expression
EXP
Ketamine results in decreased expression of PPP1R18 mRNA
CTD
PMID:20080153
NCBI chr20:2,877,567...2,887,526
Ensembl chr20:2,877,567...2,891,802
G
Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
increases expression
EXP
Ketamine results in increased expression of PPP1R1B mRNA
CTD
PMID:20080153
NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775
G
Pprc1
PPARG related coactivator 1
decreases expression
EXP
Ketamine results in decreased expression of PPRC1 mRNA
CTD
PMID:20080153
NCBI chr 1:244,901,985...244,918,587
Ensembl chr 1:244,902,179...244,918,587
G
Prkag2
protein kinase AMP-activated non-catalytic subunit gamma 2
decreases expression
EXP
Ketamine results in decreased expression of PRKAG2 mRNA
CTD
PMID:20080153
NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142
G
Prkcg
protein kinase C, gamma
increases expression
EXP
Ketamine results in increased expression of PRKCG mRNA
CTD
PMID:20080153
NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
G
Prmt2
protein arginine methyltransferase 2
decreases expression
EXP
Ketamine results in decreased expression of PRMT2 mRNA
CTD
PMID:20080153
NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643
G
Prpf38b
pre-mRNA processing factor 38B
decreases expression
EXP
Ketamine results in decreased expression of PRPF38B mRNA
CTD
PMID:20080153
NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250
G
Prpf4b
pre-mRNA processing factor 4B
decreases expression
EXP
Ketamine results in decreased expression of PRPF4B mRNA
CTD
PMID:20080153
NCBI chr17:29,985,343...30,020,285
Ensembl chr17:29,985,343...30,019,625
G
Prr16
proline rich 16
decreases expression
EXP
Ketamine results in decreased expression of PRR16 mRNA
CTD
PMID:20080153
NCBI chr18:44,424,348...44,764,796
Ensembl chr18:44,424,616...44,632,329
G
Psap
prosaposin
increases expression
EXP
Ketamine results in increased expression of PSAP mRNA
CTD
PMID:20080153
NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498
G
Ptchd1
patched domain containing 1
decreases expression
EXP
Ketamine results in decreased expression of PTCHD1 mRNA
CTD
PMID:20080153
NCBI chr X:39,681,910...39,733,416
Ensembl chr X:39,681,910...39,733,519
G
Ptk2
protein tyrosine kinase 2
decreases expression
EXP
Ketamine results in decreased expression of PTK2 mRNA
CTD
PMID:20080153
NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
G
Ptprh
protein tyrosine phosphatase, receptor type, H
decreases expression
EXP
Ketamine results in decreased expression of PTPRH mRNA
CTD
PMID:20080153
NCBI chr 1:69,243,704...69,276,294
Ensembl chr 1:69,242,321...69,285,077
G
Ptprn
protein tyrosine phosphatase, receptor type, N
increases expression
EXP
Ketamine results in increased expression of PTPRN mRNA
CTD
PMID:20080153
NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
G
Ptpru
protein tyrosine phosphatase, receptor type, U
increases expression
EXP
Ketamine results in increased expression of PTPRU mRNA
CTD
PMID:20080153
NCBI chr 5:143,950,542...144,024,791
Ensembl chr 5:143,950,965...144,024,768
G
Pvalb
parvalbumin
multiple interactions decreases expression
ISO
acetovanillone inhibits the reaction [Ketamine results in decreased expression of PVALB protein]
CTD
PMID:18063801
NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
G
Pwwp3a
PWWP domain containing 3A, DNA repair factor
decreases expression
EXP
Ketamine results in decreased expression of PWWP3A mRNA
CTD
PMID:20080153
NCBI chr 7:9,465,180...9,482,053
Ensembl chr 7:9,465,195...9,481,966
G
Pygm
glycogen phosphorylase, muscle associated
increases expression
EXP
Ketamine results in increased expression of PYGM mRNA
CTD
PMID:20080153
NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
G
Rab26
RAB26, member RAS oncogene family
increases expression
EXP
Ketamine results in increased expression of RAB26 mRNA
CTD
PMID:20080153
NCBI chr10:13,553,395...13,558,063
Ensembl chr10:13,553,395...13,558,030
G
Ramp1
receptor activity modifying protein 1
increases expression
EXP
Ketamine results in increased expression of RAMP1 mRNA
CTD
PMID:20080153
NCBI chr 9:91,765,481...91,816,152
Ensembl chr 9:91,781,285...91,816,151
G
Rasa1
RAS p21 protein activator 1
decreases expression
EXP
Ketamine results in decreased expression of RASA1 mRNA
CTD
PMID:20080153
NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
G
Rasd2
RASD family, member 2
increases expression
EXP
Ketamine results in increased expression of RASD2 mRNA
CTD
PMID:20080153
NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016
G
Rasgrf1
RAS protein-specific guanine nucleotide-releasing factor 1
increases expression
EXP
Ketamine results in increased expression of RASGRF1 mRNA
CTD
PMID:20080153
NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
G
Rasl11a
RAS-like family 11 member A
increases expression
EXP
Ketamine results in increased expression of RASL11A mRNA
CTD
PMID:20080153
NCBI chr12:8,258,148...8,260,909
Ensembl chr12:8,258,159...8,262,576
G
Rasl11b
RAS-like family 11 member B
increases expression
EXP
Ketamine results in increased expression of RASL11B mRNA
CTD
PMID:20080153
NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152
G
Rassf2
Ras association domain family member 2
decreases expression
EXP
Ketamine results in decreased expression of RASSF2 mRNA
CTD
PMID:20080153
NCBI chr 3:119,244,288...119,280,462
Ensembl chr 3:119,245,821...119,280,431
G
Rassf5
Ras association domain family member 5
increases expression
EXP
Ketamine results in increased expression of RASSF5 mRNA
CTD
PMID:20080153
NCBI chr13:42,637,513...42,703,024
Ensembl chr13:42,637,549...42,703,024
G
Rb1
RB transcriptional corepressor 1
decreases expression
EXP
Ketamine results in decreased expression of RB1 mRNA
CTD
PMID:20080153
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
G
Rbbp6
RB binding protein 6, ubiquitin ligase
increases expression
EXP
Ketamine results in increased expression of RBBP6 mRNA
CTD
PMID:20080153
NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678
G
Rbbp8
RB binding protein 8, endonuclease
decreases expression
EXP
Ketamine results in decreased expression of RBBP8 mRNA
CTD
PMID:20080153
NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
G
Rbm12b
RNA binding motif protein 12B
decreases expression
EXP
Ketamine results in decreased expression of RBM12B mRNA
CTD
PMID:20080153
NCBI chr 5:25,597,405...25,610,324
Ensembl chr 5:25,590,493...25,611,245
G
Rbm4
RNA binding motif protein 4
decreases expression
EXP
Ketamine results in decreased expression of RBM4 mRNA
CTD
PMID:20080153
NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380
G
Rbm4b
RNA binding motif protein 4B
decreases expression
EXP
Ketamine results in decreased expression of RBM4B mRNA
CTD
PMID:20080153
NCBI chr 1:202,047,934...202,058,025
Ensembl chr 1:202,047,927...202,058,020
G
Rbms1
RNA binding motif, single stranded interacting protein 1
decreases expression
EXP
Ketamine results in decreased expression of RBMS1 mRNA
CTD
PMID:20080153
NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376
G
Recql
RecQ like helicase
decreases expression
EXP
Ketamine results in decreased expression of RECQL mRNA
CTD
PMID:20080153
NCBI chr 4:175,308,337...175,332,965
Ensembl chr 4:175,304,117...175,332,945
G
Reep5
receptor accessory protein 5
decreases expression
EXP
Ketamine results in decreased expression of REEP5 mRNA
CTD
PMID:20080153
NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509
G
Rela
RELA proto-oncogene, NF-kB subunit
increases phosphorylation multiple interactions
EXP
Ketamine results in increased phosphorylation of RELA protein TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of RELA protein]
CTD
PMID:33536391
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Rem2
RRAD and GEM like GTPase 2
decreases expression
EXP
Ketamine results in decreased expression of REM2 mRNA
CTD
PMID:20080153
NCBI chr15:27,933,950...27,938,429
Ensembl chr15:27,933,950...27,938,429
G
Ren
renin
increases expression
ISO
Ketamine results in increased expression of REN protein
CTD
PMID:6349867
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Resp18
regulated endocrine-specific protein 18
increases expression
EXP
Ketamine results in increased expression of RESP18 mRNA
CTD
PMID:20080153
NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722
G
Rev1
REV1, DNA directed polymerase
increases expression
EXP
Ketamine results in increased expression of REV1 mRNA
CTD
PMID:20080153
NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576
G
Rgs19
regulator of G-protein signaling 19
decreases expression
EXP
Ketamine results in decreased expression of RGS19 mRNA
CTD
PMID:20080153
NCBI chr 3:168,804,532...168,813,035
Ensembl chr 3:168,804,874...168,810,097
G
Rgs2
regulator of G-protein signaling 2
decreases expression
EXP
Ketamine results in decreased expression of RGS2 mRNA
CTD
PMID:20080153
NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
G
Rgs9
regulator of G-protein signaling 9
increases expression
EXP
Ketamine results in increased expression of RGS9 mRNA
CTD
PMID:20080153
NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892
G
Rnase4
ribonuclease A family member 4
increases expression
EXP
Ketamine results in increased expression of RNASE4 mRNA
CTD
PMID:20080153
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
G
Rnd3
Rho family GTPase 3
decreases expression
EXP
Ketamine results in decreased expression of RND3 mRNA
CTD
PMID:20080153
NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327
G
Rnf112
ring finger protein 112
increases expression
EXP
Ketamine results in increased expression of RNF112 mRNA
CTD
PMID:20080153
NCBI chr10:46,121,146...46,126,691
Ensembl chr10:46,121,148...46,126,699
G
Rnf138
ring finger protein 138
decreases expression
EXP
Ketamine results in decreased expression of RNF138 mRNA
CTD
PMID:20080153
NCBI chr18:12,291,557...12,315,931
Ensembl chr18:12,291,590...12,315,930
G
Rnf31
ring finger protein 31
increases expression
EXP
Ketamine results in increased expression of RNF31 mRNA
CTD
PMID:20080153
NCBI chr15:29,083,047...29,095,328
Ensembl chr15:29,083,631...29,101,915
G
Rnls
renalase, FAD-dependent amine oxidase
increases expression
EXP
Ketamine results in increased expression of RNLS mRNA
CTD
PMID:20080153
NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823
G
Rora
RAR-related orphan receptor A
increases expression
EXP
Ketamine results in increased expression of RORA mRNA
CTD
PMID:20080153
NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
G
Rpf2
ribosome production factor 2 homolog
decreases expression
EXP
Ketamine results in decreased expression of RPF2 mRNA
CTD
PMID:20080153
NCBI chr20:43,630,003...43,651,477
Ensembl chr20:43,629,951...43,651,509
G
Rpusd3
RNA pseudouridine synthase D3
increases expression
EXP
Ketamine results in increased expression of RPUSD3 mRNA
CTD
PMID:20080153
NCBI chr 4:146,553,743...146,562,789
Ensembl chr 4:146,558,562...146,562,794
G
Rras2
RAS related 2
decreases expression
EXP
Ketamine results in decreased expression of RRAS2 mRNA
CTD
PMID:20080153
NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
G
Rrm2
ribonucleotide reductase regulatory subunit M2
decreases expression
EXP
Ketamine results in decreased expression of RRM2 mRNA
CTD
PMID:20080153
NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
G
Rrp1b
ribosomal RNA processing 1B
increases expression
EXP
Ketamine results in increased expression of RRP1B mRNA
CTD
PMID:20080153
NCBI chr20:10,123,111...10,148,704
Ensembl chr20:10,123,125...10,147,928
G
Rrp7a
ribosomal RNA processing 7 homolog A
decreases expression
EXP
Ketamine results in decreased expression of RRP7A mRNA
CTD
PMID:20080153
NCBI chr 7:114,262,929...114,272,817
Ensembl chr 7:114,256,472...114,272,817
G
RT1-S3
RT1 class Ib, locus S3
increases expression
EXP
Ketamine results in increased expression of RT1-S3 mRNA
CTD
PMID:20080153
NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
G
RT1-T24-4
RT1 class I, locus T24, gene 4
increases expression
EXP
Ketamine results in increased expression of RT1-T24-4 mRNA
CTD
PMID:20080153
NCBI chr20:2,684,515...2,747,878
Ensembl chr20:2,684,515...2,692,511
G
Rtkn
rhotekin
increases expression
EXP
Ketamine results in increased expression of RTKN mRNA
CTD
PMID:20080153
NCBI chr 4:115,640,813...115,657,952
Ensembl chr 4:115,640,774...115,657,952
G
Rundc3a
RUN domain containing 3A
increases expression
EXP
Ketamine results in increased expression of RUNDC3A mRNA
CTD
PMID:20080153
NCBI chr10:87,352,624...87,361,767
Ensembl chr10:87,352,646...87,361,765
G
Rwdd2a
RWD domain containing 2A
increases expression
EXP
Ketamine results in increased expression of RWDD2A mRNA
CTD
PMID:20080153
NCBI chr 8:87,536,153...87,539,301
Ensembl chr 8:87,536,176...87,539,300
G
Rxfp1
relaxin family peptide receptor 1
decreases expression
EXP
Ketamine results in decreased expression of RXFP1 mRNA
CTD
PMID:20080153
NCBI chr 2:164,772,270...164,893,484
Ensembl chr 2:164,774,799...164,893,412
G
Rxrg
retinoid X receptor gamma
decreases expression
EXP
Ketamine results in decreased expression of RXRG mRNA
CTD
PMID:20080153
NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
G
S100a11
S100 calcium binding protein A11
decreases expression
EXP
Ketamine results in decreased expression of S100A11 mRNA
CTD
PMID:20080153
NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044
G
S100a4
S100 calcium-binding protein A4
increases expression
EXP ISO
Ketamine results in increased expression of S100A4 mRNA
CTD
PMID:20080153 PMID:28331066
NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
G
S100b
S100 calcium binding protein B
increases expression
EXP
Ketamine results in increased expression of S100B mRNA
CTD
PMID:20080153
NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
G
S1pr2
sphingosine-1-phosphate receptor 2
decreases expression
EXP
Ketamine results in decreased expression of S1PR2 mRNA
CTD
PMID:20080153
NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574
G
Samd9l
sterile alpha motif domain containing 9 like
decreases expression
EXP
Ketamine results in decreased expression of SAMD9L mRNA
CTD
PMID:20080153
NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415
G
Satb2
SATB homeobox 2
decreases expression
EXP
Ketamine results in decreased expression of SATB2 mRNA
CTD
PMID:20080153
NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707
G
Scaper
S-phase cyclin A-associated protein in the ER
decreases expression
EXP
Ketamine results in decreased expression of SCAPER mRNA
CTD
PMID:20080153
NCBI chr 8:55,932,717...56,332,222
Ensembl chr 8:55,933,306...56,332,122
G
Scara3
scavenger receptor class A, member 3
increases expression
EXP
Ketamine results in increased expression of SCARA3 mRNA
CTD
PMID:20080153
NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894
G
Scarf2
scavenger receptor class F, member 2
increases expression
EXP
Ketamine results in increased expression of SCARF2 mRNA
CTD
PMID:20080153
NCBI chr11:83,175,956...83,187,415
Ensembl chr11:83,175,963...83,187,348
G
Scd
stearoyl-CoA desaturase
increases expression
EXP
Ketamine results in increased expression of SCD1 mRNA
CTD
PMID:20080153
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scn4b
sodium voltage-gated channel beta subunit 4
increases expression
EXP
Ketamine results in increased expression of SCN4B mRNA
CTD
PMID:20080153
NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292
G
Sdc1
syndecan 1
decreases expression
EXP
Ketamine results in decreased expression of SDC1 mRNA
CTD
PMID:20080153
NCBI chr 6:31,562,799...31,585,267
Ensembl chr 6:31,562,739...31,585,264
G
Sdsl
serine dehydratase-like
increases expression
EXP
Ketamine results in increased expression of SDSL mRNA
CTD
PMID:20080153
NCBI chr12:36,099,693...36,109,914
Ensembl chr12:36,099,693...36,109,906
G
Senp7
SUMO specific peptidase 7
decreases expression
EXP
Ketamine results in decreased expression of SENP7 mRNA
CTD
PMID:20080153
NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711
G
Septin4
septin 4
increases expression
EXP
Ketamine results in increased expression of SEPTIN4 mRNA
CTD
PMID:20080153
NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768
G
Serpinb1a
serpin family B member 1A
increases expression
EXP
Ketamine results in increased expression of SERPINB1A mRNA
CTD
PMID:20080153
NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
G
Sesn1
sestrin 1
increases expression
EXP
Ketamine results in increased expression of SESN1 mRNA
CTD
PMID:20080153
NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697
G
Setmar
SET domain and mariner transposase fusion gene
decreases expression
EXP
Ketamine results in decreased expression of SETMAR mRNA
CTD
PMID:20080153
NCBI chr 4:141,046,058...141,058,183
Ensembl chr 4:141,046,069...141,058,197
G
Sfpq
splicing factor proline and glutamine rich
decreases expression
EXP
Ketamine results in decreased expression of SFPQ mRNA
CTD
PMID:20080153
NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
G
Sh2b2
SH2B adaptor protein 2
decreases expression
EXP
Ketamine results in decreased expression of SH2B2 mRNA
CTD
PMID:20080153
NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
G
Shoc2
SHOC2 leucine-rich repeat scaffold protein
decreases expression
EXP
Ketamine results in decreased expression of SHOC2 mRNA
CTD
PMID:20080153
NCBI chr 1:252,958,939...253,048,820
Ensembl chr 1:252,959,723...253,047,337
G
Slain2
SLAIN motif family, member 2
decreases expression
EXP
Ketamine results in decreased expression of SLAIN2 mRNA
CTD
PMID:20080153
NCBI chr14:35,236,034...35,314,186
Ensembl chr14:35,236,041...35,304,678
G
Slc15a5
solute carrier family 15, member 5
decreases expression
EXP
Ketamine results in decreased expression of SLC15A5 mRNA
CTD
PMID:20080153
NCBI chr 4:170,878,021...170,971,620
Ensembl chr 4:170,878,021...170,971,620
G
Slc17a7
solute carrier family 17 member 7
increases expression
EXP
Ketamine results in increased expression of SLC17A7 mRNA
CTD
PMID:20080153
NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
G
Slc1a2
solute carrier family 1 member 2
increases expression multiple interactions
EXP ISO
Ketamine results in increased expression of SLC1A2 mRNA [Guanosine co-treated with Ketamine] results in increased expression of SLC1A2 protein
CTD
PMID:20080153 PMID:36878458
NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498
G
Slc20a2
solute carrier family 20 member 2
increases expression
EXP
Ketamine results in increased expression of SLC20A2 mRNA
CTD
PMID:20080153
NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711
G
Slc25a1
solute carrier family 25 member 1
decreases expression
EXP
Ketamine results in decreased expression of SLC25A1 mRNA
CTD
PMID:20080153
NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781
G
Slc26a6
solute carrier family 26 member 6
increases expression
EXP
Ketamine results in increased expression of SLC26A6 mRNA
CTD
PMID:20080153
NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778
G
Slc2a2
solute carrier family 2 member 2
increases expression
EXP
Ketamine results in increased expression of SLC2A2 mRNA
CTD
PMID:20080153
NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
G
Slc2a5
solute carrier family 2 member 5
increases expression
EXP
Ketamine results in increased expression of SLC2A5 mRNA
CTD
PMID:20080153
NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
G
Slc2a6
solute carrier family 2 member 6
decreases expression
EXP
Ketamine results in decreased expression of SLC2A6 mRNA
CTD
PMID:20080153
NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
G
Slc30a6
solute carrier family 30 member 6
decreases expression
EXP
Ketamine results in decreased expression of SLC30A6 mRNA
CTD
PMID:20080153
NCBI chr 6:21,020,931...21,050,785
Ensembl chr 6:21,020,931...21,050,785
G
Slc32a1
solute carrier family 32 member 1
increases expression
EXP
Ketamine results in increased expression of SLC32A1 mRNA
CTD
PMID:20080153
NCBI chr 3:147,267,373...147,271,842
Ensembl chr 3:147,267,373...147,271,844
G
Slc35e3
solute carrier family 35, member E3
decreases expression
EXP
Ketamine results in decreased expression of SLC35E3 mRNA
CTD
PMID:20080153
NCBI chr 7:53,337,091...53,350,152
Ensembl chr 7:53,337,095...53,350,165
G
Slc38a3
solute carrier family 38, member 3
increases expression
EXP
Ketamine results in increased expression of SLC38A3 mRNA
CTD
PMID:20080153
NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
G
Slc38a5
solute carrier family 38, member 5
decreases expression
EXP
Ketamine results in decreased expression of SLC38A5 mRNA
CTD
PMID:20080153
NCBI chr X:14,213,727...14,222,498
Ensembl chr X:14,213,729...14,222,498
G
Slc39a12
solute carrier family 39 member 12
increases expression
EXP
Ketamine results in increased expression of SLC39A12 mRNA
CTD
PMID:20080153
NCBI chr17:77,353,761...77,440,384
Ensembl chr17:77,353,805...77,440,353
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Slc45a4
solute carrier family 45, member 4
increases expression
EXP
Ketamine results in increased expression of SLC45A4 mRNA
CTD
PMID:20080153
NCBI chr 7:105,478,886...105,550,160
Ensembl chr 7:105,481,792...105,550,170
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Slc52a2
solute carrier family 52 member 2
decreases expression
EXP
Ketamine results in decreased expression of SLC52A2 mRNA
CTD
PMID:20080153
NCBI chr 7:108,246,003...108,267,642
Ensembl chr 7:108,262,612...108,268,034
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Slc5a3
solute carrier family 5 member 3
decreases expression
EXP
Ketamine results in decreased expression of SLC5A3 mRNA
CTD
PMID:20080153
NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
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Slc6a2
solute carrier family 6 member 2
multiple interactions decreases activity
ISO
[Ketamine co-treated with Xylenes] results in decreased activity of SLC6A2 protein Ketamine results in decreased activity of SLC6A2 protein
CTD
PMID:17934728
NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357
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Slc6a3
solute carrier family 6 member 3
multiple interactions
ISO
Ketamine inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine]
CTD
PMID:31009648
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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Slc7a10
solute carrier family 7 member 10
increases expression
EXP
Ketamine results in increased expression of SLC7A10 mRNA
CTD
PMID:20080153
NCBI chr 1:87,829,084...87,845,073
Ensembl chr 1:87,829,175...87,845,071
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Slc9a1
solute carrier family 9 member A1
increases expression
EXP
Ketamine results in increased expression of SLC9A1 mRNA
CTD
PMID:20080153
NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
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Slc9a6
solute carrier family 9 member A6
decreases expression
ISO
Ketamine results in decreased expression of SLC9A6 protein
CTD
PMID:35378374
NCBI chr X:134,430,677...134,486,747
Ensembl chr X:134,420,756...134,485,375
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Slco1c1
solute carrier organic anion transporter family, member 1c1
decreases expression
EXP
Ketamine results in decreased expression of SLCO1C1 mRNA
CTD
PMID:20080153
NCBI chr 4:174,466,621...174,513,290
Ensembl chr 4:174,466,631...174,513,289
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Slco5a1
solute carrier organic anion transporter family, member 5A1
decreases expression
EXP
Ketamine results in decreased expression of SLCO5A1 mRNA
CTD
PMID:20080153
NCBI chr 5:6,228,938...6,358,124
Ensembl chr 5:6,228,973...6,352,913
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Sltm
SAFB-like, transcription modulator
decreases expression
EXP
Ketamine results in decreased expression of SLTM mRNA
CTD
PMID:20080153
NCBI chr 8:71,215,995...71,261,821
Ensembl chr 8:71,216,612...71,261,825
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Smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
decreases expression
EXP
Ketamine results in decreased expression of SMARCA1 mRNA
CTD
PMID:20080153
NCBI chr X:126,980,201...127,066,385
Ensembl chr X:126,994,947...127,066,347
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Smc6
structural maintenance of chromosomes 6
decreases expression
EXP
Ketamine results in decreased expression of SMC6 mRNA
CTD
PMID:20080153
NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746
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Smoc2
SPARC related modular calcium binding 2
decreases expression
EXP
Ketamine results in decreased expression of SMOC2 mRNA
CTD
PMID:20080153
NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693
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Smox
spermine oxidase
increases expression
EXP
Ketamine results in increased expression of SMOX mRNA
CTD
PMID:20080153
NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
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Snai1
snail family transcriptional repressor 1
increases expression
ISO
Ketamine results in increased expression of SNAI1 mRNA
CTD
PMID:28331066
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Snai2
snail family transcriptional repressor 2
increases expression
ISO
Ketamine results in increased expression of SNAI2 mRNA
CTD
PMID:28331066
NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200
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Snapc3
small nuclear RNA activating complex, polypeptide 3
decreases expression
EXP
Ketamine results in decreased expression of SNAPC3 mRNA
CTD
PMID:20080153
NCBI chr 5:97,817,827...97,868,494
Ensembl chr 5:97,817,947...97,844,650
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Snorc
secondary ossification center associated regulator of chondrocyte maturation
increases expression
EXP
Ketamine results in increased expression of SNORC mRNA
CTD
PMID:20080153
NCBI chr 9:88,140,510...88,145,527
Ensembl chr 9:88,140,419...88,145,891
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Snta1
syntrophin, alpha 1
increases expression
EXP
Ketamine results in increased expression of SNTA1 mRNA
CTD
PMID:20080153
NCBI chr 3:142,876,285...142,906,737
Ensembl chr 3:142,876,296...142,906,709
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Sntg2
syntrophin, gamma 2
decreases expression
EXP
Ketamine results in decreased expression of SNTG2 mRNA
CTD
PMID:20080153
NCBI chr 6:46,801,893...47,003,390
Ensembl chr 6:46,801,377...47,003,372
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Snx16
sorting nexin 16
decreases expression
EXP
Ketamine results in decreased expression of SNX16 mRNA
CTD
PMID:20080153
NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619
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Socs3
suppressor of cytokine signaling 3
multiple interactions
ISO
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of SOCS3 mRNA]
CTD
PMID:22245128
NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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Socs5
suppressor of cytokine signaling 5
decreases expression
EXP
Ketamine results in decreased expression of SOCS5 mRNA
CTD
PMID:20080153
NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
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Sod3
superoxide dismutase 3
increases expression
EXP
Ketamine results in increased expression of SOD3 mRNA
CTD
PMID:20080153
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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Sorcs1
sortilin-related VPS10 domain containing receptor 1
decreases expression
EXP
Ketamine results in decreased expression of SORCS1 mRNA
CTD
PMID:20080153
NCBI chr 1:249,080,662...249,594,520
Ensembl chr 1:249,081,355...249,594,507
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Sox11
SRY-box transcription factor 11
decreases expression
EXP
Ketamine results in decreased expression of SOX11 mRNA
CTD
PMID:20080153
NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
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Sox4
SRY-box transcription factor 4
decreases expression
EXP
Ketamine results in decreased expression of SOX4 mRNA
CTD
PMID:20080153
NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
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Spatc1
spermatogenesis and centriole associated 1
decreases expression
EXP
Ketamine results in decreased expression of SPATC1 mRNA
CTD
PMID:20080153
NCBI chr 7:107,980,857...108,007,716
Ensembl chr 7:107,983,796...108,007,479
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Spdya
speedy/RINGO cell cycle regulator family member A
increases expression
EXP
Ketamine results in increased expression of SPDYA mRNA
CTD
PMID:20080153
NCBI chr 6:23,905,574...23,954,926
Ensembl chr 6:23,910,223...23,954,850
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Spsb1
splA/ryanodine receptor domain and SOCS box containing 1
increases expression
EXP
Ketamine results in increased expression of SPSB1 mRNA
CTD
PMID:20080153
NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
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Sptbn4
spectrin, beta, non-erythrocytic 4
increases expression
EXP
Ketamine results in increased expression of SPTBN4 mRNA
CTD
PMID:20080153
NCBI chr 1:82,650,750...82,738,345
Ensembl chr 1:82,650,751...82,737,228
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Sqle
squalene epoxidase
decreases expression
EXP
Ketamine results in decreased expression of SQLE mRNA
CTD
PMID:20080153
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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Sqstm1
sequestosome 1
increases expression
ISO
Ketamine results in increased expression of SQSTM1 mRNA; Ketamine results in increased expression of SQSTM1 protein
CTD
PMID:34487425
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srebf1
sterol regulatory element binding transcription factor 1
increases expression
EXP
Ketamine results in increased expression of SREBF1 mRNA
CTD
PMID:20080153
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srpk1
SRSF protein kinase 1
decreases expression
EXP
Ketamine results in decreased expression of SRPK1 mRNA
CTD
PMID:20080153
NCBI chr20:6,645,809...6,682,448
Ensembl chr20:6,645,809...6,682,134
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Srsf6
serine and arginine rich splicing factor 6
decreases expression
EXP
Ketamine results in decreased expression of SFRS6 mRNA
CTD
PMID:20080153
NCBI chr 3:151,589,546...151,594,869
Ensembl chr 3:151,589,535...151,594,860
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Ssr1
signal sequence receptor subunit 1
increases expression
EXP
Ketamine results in increased expression of SSR1 mRNA
CTD
PMID:20080153
NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821
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Sstr1
somatostatin receptor 1
decreases expression
EXP
Ketamine results in decreased expression of SSTR1 mRNA
CTD
PMID:20080153
NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
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Stim1
stromal interaction molecule 1
increases expression
EXP
Ketamine results in increased expression of STIM1 mRNA
CTD
PMID:20080153
NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
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Sult1a1
sulfotransferase family 1A member 1
increases expression
EXP
Ketamine results in increased expression of SULT1A1 mRNA
CTD
PMID:20080153
NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
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Sumf1
sulfatase modifying factor 1
increases expression
EXP
Ketamine results in increased expression of SUMF1 mRNA
CTD
PMID:20080153
NCBI chr 4:141,078,735...141,160,711
Ensembl chr 4:141,078,741...141,160,708
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Suox
sulfite oxidase
decreases expression
EXP
Ketamine results in decreased expression of SUOX mRNA
CTD
PMID:20080153
NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
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Syn1
synapsin I
multiple interactions increases expression
ISO
Ketamine inhibits the reaction [Corticosterone results in decreased expression of SYN1 protein]; Sirolimus inhibits the reaction [Ketamine results in increased expression of SYN1 protein]
CTD
PMID:33022268 PMID:33872575
NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396
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Syt12
synaptotagmin 12
increases expression
EXP
Ketamine results in increased expression of SYT12 mRNA
CTD
PMID:20080153
NCBI chr 1:201,729,307...201,760,192
Ensembl chr 1:201,730,371...201,759,609
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Sytl2
synaptotagmin-like 2
increases expression
EXP
Ketamine results in increased expression of SYTL2 mRNA
CTD
PMID:20080153
NCBI chr 1:144,272,870...144,379,310
Ensembl chr 1:144,273,360...144,379,222
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Tac3
tachykinin precursor 3
increases expression
EXP
Ketamine results in increased expression of TAC2 mRNA
CTD
PMID:20080153
NCBI chr 7:63,562,552...63,569,170
Ensembl chr 7:63,562,552...63,569,170
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Tacstd2
tumor-associated calcium signal transducer 2
decreases expression
EXP
Ketamine results in decreased expression of TACSTD2 mRNA
CTD
PMID:20080153
NCBI chr 4:96,707,950...96,709,650
Ensembl chr 4:96,707,951...96,709,650
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Tafa1
TAFA chemokine like family member 1
decreases expression
EXP
Ketamine results in decreased expression of TAFA1 mRNA
CTD
PMID:20080153
NCBI chr 4:128,738,028...129,244,223
Ensembl chr 4:128,739,313...129,243,777
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Tagln3
transgelin 3
increases expression
EXP
Ketamine results in increased expression of TAGLN3 protein
CTD
PMID:18504422
NCBI chr11:55,099,887...55,113,457
Ensembl chr11:55,099,743...55,113,485
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Tax1bp3
Tax1 binding protein 3
decreases expression
EXP
Ketamine results in decreased expression of TAX1BP3 mRNA
CTD
PMID:20080153
NCBI chr10:57,795,845...57,800,363
Ensembl chr10:57,795,382...57,800,363
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Tbc1d10b
TBC1 domain family, member 10b
decreases expression
EXP
Ketamine results in decreased expression of TBC1D10B mRNA
CTD
PMID:20080153
NCBI chr 1:181,814,972...181,826,628
Ensembl chr 1:181,814,972...181,826,628
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Tbccd1
TBCC domain containing 1
decreases expression
EXP
Ketamine results in decreased expression of TBCCD1 mRNA
CTD
PMID:20080153
NCBI chr11:78,168,386...78,205,314
Ensembl chr11:78,168,388...78,205,523
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Tef
TEF transcription factor, PAR bZIP family member
increases expression
EXP
Ketamine results in increased expression of TEF mRNA
CTD
PMID:20080153
NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783
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Tekt2
tektin 2
increases expression
EXP
Ketamine results in increased expression of TEKT2 mRNA
CTD
PMID:20080153
NCBI chr 5:138,619,665...138,623,301
Ensembl chr 5:138,619,667...138,623,204
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Tes
testin LIM domain protein
decreases expression
EXP
Ketamine results in decreased expression of TES mRNA
CTD
PMID:20080153
NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829
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Tesc
tescalcin
increases expression
EXP
Ketamine results in increased expression of TESC mRNA
CTD
PMID:20080153
NCBI chr12:38,521,832...38,555,665
Ensembl chr12:38,521,861...38,555,824
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Tf
transferrin
increases expression
EXP
Ketamine results in increased expression of TF mRNA
CTD
PMID:20080153
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
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Tfap2d
transcription factor AP-2 delta
decreases expression
EXP
Ketamine results in decreased expression of TFAP2D mRNA
CTD
PMID:20080153
NCBI chr 9:21,680,577...21,744,840
Ensembl chr 9:21,680,577...21,740,728
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Tfe3
transcription factor binding to IGHM enhancer 3
increases expression
EXP
Ketamine results in increased expression of TFE3 mRNA
CTD
PMID:20080153
NCBI chr X:14,729,547...14,742,830
Ensembl chr X:14,729,550...14,742,571
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Tgfb1
transforming growth factor, beta 1
increases expression increases secretion
EXP ISO
Ketamine results in increased expression of TGFB1 protein Ketamine results in increased expression of TGFB1 mRNA Ketamine results in increased secretion of TGFB1 protein
CTD
PMID:28331066
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbr1
transforming growth factor, beta receptor 1
increases expression
ISO
Ketamine results in increased expression of TGFBR1 mRNA
CTD
PMID:28331066
NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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Tgfbr2
transforming growth factor, beta receptor 2
increases expression
ISO
Ketamine results in increased expression of TGFBR2 mRNA
CTD
PMID:28331066
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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Thnsl2
threonine synthase-like 2
increases expression
EXP
Ketamine results in increased expression of THNSL2 mRNA
CTD
PMID:20080153
NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
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Thrsp
thyroid hormone responsive
increases expression
EXP
Ketamine results in increased expression of THRSP mRNA
CTD
PMID:20080153
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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Thumpd3
THUMP domain containing 3
decreases expression
EXP
Ketamine results in decreased expression of THUMPD3 mRNA
CTD
PMID:20080153
NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246
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Thy1
Thy-1 cell surface antigen
increases expression
EXP
Ketamine results in increased expression of THY1 mRNA
CTD
PMID:20080153
NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659
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Tia1
TIA1 cytotoxic granule-associated RNA binding protein
decreases expression
EXP
Ketamine results in decreased expression of TIA1 mRNA
CTD
PMID:20080153
NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586
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Tifa
TRAF-interacting protein with forkhead-associated domain
increases expression
EXP
Ketamine results in increased expression of TIFA mRNA
CTD
PMID:20080153
NCBI chr 2:216,257,926...216,267,635
Ensembl chr 2:216,234,774...216,267,841
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Tigd2
tigger transposable element derived 2
increases expression
EXP
Ketamine results in increased expression of TIGD2 mRNA
CTD
PMID:20080153
NCBI chr 4:88,414,366...88,417,458
Ensembl chr 4:88,414,518...88,417,785
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Tlcd3a
TLC domain containing 3A
decreases expression
EXP
Ketamine results in decreased expression of TLCD3A mRNA
CTD
PMID:20080153
NCBI chr10:61,057,470...61,065,293
Ensembl chr10:61,058,042...61,065,283
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Tlr4
toll-like receptor 4
multiple interactions
ISO
TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; TLR4 mutant form promotes the reaction [Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]
CTD
PMID:19540866
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
decreases expression
EXP
Ketamine results in decreased expression of TMEFF1 mRNA
CTD
PMID:20080153
NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:62,910,740...62,996,493
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Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
decreases expression
EXP
Ketamine results in decreased expression of TMEFF2 mRNA
CTD
PMID:20080153
NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475
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Tmem140
transmembrane protein 140
increases expression
EXP
Ketamine results in increased expression of TMEM140 mRNA
CTD
PMID:20080153
NCBI chr 4:63,536,477...63,547,478
Ensembl chr 4:63,536,168...63,548,455
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Tmem200a
transmembrane protein 200A
decreases expression
EXP
Ketamine results in decreased expression of TMEM200A mRNA
CTD
PMID:20080153
NCBI chr 1:19,323,646...19,408,324
Ensembl chr 1:19,323,829...19,406,453
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Tmem222
transmembrane protein 222
increases expression
EXP
Ketamine results in increased expression of TMEM222 mRNA
CTD
PMID:20080153
NCBI chr 5:145,465,847...145,477,932
Ensembl chr 5:145,465,847...145,484,491
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Tmem248
transmembrane protein 248
increases expression
EXP
Ketamine results in increased expression of TMEM248 mRNA
CTD
PMID:20080153
NCBI chr12:26,430,775...26,457,105
Ensembl chr12:26,432,953...26,457,105
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Tmem74
transmembrane protein 74
decreases expression
EXP
Ketamine results in decreased expression of TMEM74 mRNA
CTD
PMID:20080153
NCBI chr 7:74,929,290...74,937,929
Ensembl chr 7:74,931,694...74,937,934
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Tmem74b
transmembrane protein 74B
decreases expression
EXP
Ketamine results in decreased expression of TMEM74B mRNA
CTD
PMID:20080153
NCBI chr 3:140,219,592...140,224,208
Ensembl chr 3:140,219,412...140,235,872
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Tmpo
thymopoietin
decreases expression
EXP
Ketamine results in decreased expression of TMPO mRNA
CTD
PMID:20080153
NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
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Tmtc4
transmembrane O-mannosyltransferase targeting cadherins 4
decreases expression
EXP
Ketamine results in decreased expression of TMTC4 mRNA
CTD
PMID:20080153
NCBI chr15:100,000,157...100,056,573
Ensembl chr15:100,000,152...100,056,543
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Tnf
tumor necrosis factor
multiple interactions increases expression affects expression decreases expression
ISO EXP IEP
Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] Ketamine results in increased expression of TNF protein Ketamine co-treated with xylazine inhibits the reaction [lipopolysaccharide increases expression of Tnf protein in serum and mucosa of stomach] [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF mRNA]; [Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of TNF protein]; Ketamine inhibits the reaction [Acetaminophen results in increased expression of TNF protein]; Ketamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] Ozone inhibits the reaction [Ketamine results in decreased expression of TNF mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of TNF protein]
CTD RGD
PMID:15207037 PMID:15207038 PMID:15720977 PMID:19540866 PMID:22245128 PMID:33536391 PMID:37491939 PMID:12813371 More...
RGD:14995427
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip1
TNF alpha induced protein 1
decreases expression
EXP
Ketamine results in decreased expression of TNFAIP1 mRNA
CTD
PMID:20080153
NCBI chr10:63,417,774...63,432,466
Ensembl chr10:63,417,775...63,432,466
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Tnfrsf11b
TNF receptor superfamily member 11B
decreases expression
EXP
Ketamine results in decreased expression of TNFRSF11B mRNA
CTD
PMID:20080153
NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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Tnnc2
troponin C2, fast skeletal type
increases expression
EXP
Ketamine results in increased expression of TNNC2 mRNA
CTD
PMID:20080153
NCBI chr 3:153,513,272...153,516,033
Ensembl chr 3:153,513,271...153,516,029
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Tnnt1
troponin T1, slow skeletal type
increases expression
ISO
Ketamine results in increased expression of TNNT1 mRNA
CTD
PMID:19162068
NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
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Tnpo1
transportin 1
decreases expression
EXP
Ketamine results in decreased expression of TNPO1 mRNA
CTD
PMID:20080153
NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
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Tns3
tensin 3
increases expression
EXP
Ketamine results in increased expression of TNS3 mRNA
CTD
PMID:20080153
NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
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Tp53
tumor protein p53
increases expression
ISO
Ketamine results in increased expression of TP53 protein
CTD
PMID:19919587
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpm1
tropomyosin 1
increases expression
EXP
Ketamine results in increased expression of TPM1 mRNA
CTD
PMID:20080153
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
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Tpm4
tropomyosin 4
decreases expression
EXP
Ketamine results in decreased expression of TPM4 mRNA
CTD
PMID:20080153
NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
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Tra2a
transformer 2 alpha
decreases expression
EXP
Ketamine results in decreased expression of TRA2A mRNA
CTD
PMID:20080153
NCBI chr 4:78,220,838...78,239,737
Ensembl chr 4:78,220,883...78,239,712
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Traip
TRAF-interacting protein
increases expression
EXP
Ketamine results in increased expression of TRAIP mRNA
CTD
PMID:20080153
NCBI chr 8:108,641,860...108,661,640
Ensembl chr 8:108,641,852...108,661,638
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Trem2
triggering receptor expressed on myeloid cells 2
increases expression
EXP
Ketamine results in increased expression of TREM2 mRNA
CTD
PMID:20080153
NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170
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Trh
thyrotropin releasing hormone
increases expression
EXP
Ketamine results in increased expression of TRH mRNA
CTD
PMID:20080153
NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
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Trim13
tripartite motif-containing 13
decreases expression
EXP
Ketamine results in decreased expression of TRIM13 mRNA
CTD
PMID:20080153
NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677
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Trim36
tripartite motif-containing 36
decreases expression
EXP
Ketamine results in decreased expression of TRIM36 mRNA
CTD
PMID:20080153
NCBI chr18:38,859,604...38,912,859
Ensembl chr18:38,861,018...38,912,859
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Trim39
tripartite motif-containing 39
decreases expression
EXP
Ketamine results in decreased expression of TRIM39 mRNA
CTD
PMID:20080153
NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
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Trim54
tripartite motif-containing 54
increases expression
EXP
Ketamine results in increased expression of TRIM54 mRNA
CTD
PMID:20080153
NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511
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Trpc3
transient receptor potential cation channel, subfamily C, member 3
decreases expression multiple interactions
EXP
Ketamine results in decreased expression of TRPC3 mRNA; Ketamine results in decreased expression of TRPC3 protein Chir 99021 promotes the reaction [Ketamine results in decreased expression of TRPC3 protein]
CTD
PMID:36334642
NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855
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Trpv2
transient receptor potential cation channel, subfamily V, member 2
decreases expression
EXP
Ketamine results in decreased expression of TRPV2 mRNA
CTD
PMID:20080153
NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
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Trpv4
transient receptor potential cation channel, subfamily V, member 4
increases expression multiple interactions
EXP
Ketamine results in increased expression of TRPV4 mRNA; Ketamine results in increased expression of TRPV4 protein TRPV4 protein affects the reaction [Ketamine results in decreased activity of CAT protein]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 mRNA]; TRPV4 protein affects the reaction [Ketamine results in decreased expression of BCL2 protein]; TRPV4 protein affects the reaction [Ketamine results in increased cleavage of CASP3 protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of BAX protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of CASP3 mRNA]; TRPV4 protein affects the reaction [Ketamine results in increased expression of IL1B protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of IL6 protein]; TRPV4 protein affects the reaction [Ketamine results in increased expression of TNF protein]; TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of NFKBIA protein]; TRPV4 protein affects the reaction [Ketamine results in increased phosphorylation of RELA protein]
CTD
PMID:33536391
NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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Tsen2
tRNA splicing endonuclease subunit 2
decreases expression
EXP
Ketamine results in decreased expression of TSEN2 mRNA
CTD
PMID:20080153
NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215
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Tspan14
tetraspanin 14
decreases expression
EXP
Ketamine results in decreased expression of TSPAN14 mRNA
CTD
PMID:20080153
NCBI chr16:16,784,242...16,841,368
Ensembl chr16:16,783,234...16,841,400
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Tspan33
tetraspanin 33
increases expression
EXP
Ketamine results in increased expression of TSPAN33 mRNA
CTD
PMID:20080153
NCBI chr 4:58,305,378...58,330,013
Ensembl chr 4:58,305,437...58,328,940
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Tspo
translocator protein
multiple interactions
EXP
[Ketamine co-treated with Midazolam co-treated with Valproic Acid] inhibits the reaction [[Sarin co-treated with [Atropine co-treated with trimethylene-bis(4-hydroxyiminomethylpyridinium)]] results in increased expression of TSPO protein]
CTD
PMID:33823148
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
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Ttc14
tetratricopeptide repeat domain 14
decreases expression
EXP
Ketamine results in decreased expression of TTC14 mRNA
CTD
PMID:20080153
NCBI chr 2:116,653,543...116,665,072
Ensembl chr 2:116,653,595...116,664,158
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Ttc21b
tetratricopeptide repeat domain 21B
decreases expression
EXP
Ketamine results in decreased expression of TTC21B mRNA
CTD
PMID:20080153
NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903
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Ttll1
TTL family tubulin polyglutamylase complex subunit L1
decreases expression
EXP
Ketamine results in decreased expression of TTLL1 mRNA
CTD
PMID:20080153
NCBI chr 7:114,619,509...114,648,850
Ensembl chr 7:114,619,508...114,648,761
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Ttll7
tubulin tyrosine ligase like 7
decreases expression
EXP
Ketamine results in decreased expression of TTLL7 mRNA
CTD
PMID:20080153
NCBI chr 2:235,765,786...235,889,047
Ensembl chr 2:235,765,835...235,885,047
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Tuba1c
tubulin, alpha 1C
decreases expression
EXP
Ketamine results in decreased expression of TUBA1C protein
CTD
PMID:18504422
NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647 Ensembl chr X:130,192,016...130,199,647
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Tuba4a
tubulin, alpha 4A
increases expression
EXP
Ketamine results in increased expression of TUBA4A mRNA
CTD
PMID:20080153
NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
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Twist1
twist family bHLH transcription factor 1
increases expression
ISO
Ketamine results in increased expression of TWIST1 mRNA
CTD
PMID:28331066
NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653
G
Txndc17
thioredoxin domain containing 17
decreases expression
EXP
Ketamine results in decreased expression of TXNDC17 mRNA
CTD
PMID:20080153
NCBI chr10:56,832,749...56,835,721
G
Txnip
thioredoxin interacting protein
increases expression
EXP
Ketamine results in increased expression of TXNIP mRNA
CTD
PMID:20080153
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Tyms
thymidylate synthetase
decreases expression
EXP
Ketamine results in decreased expression of TYMS mRNA
CTD
PMID:20080153
NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
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U2surp
U2 snRNP-associated SURP domain containing
decreases expression
EXP
Ketamine results in decreased expression of U2SURP mRNA
CTD
PMID:20080153
NCBI chr 8:96,018,932...96,075,795
Ensembl chr 8:96,022,957...96,075,691
G
Uap1
UDP-N-acetylglucosamine pyrophosphorylase 1
decreases expression
EXP
Ketamine results in decreased expression of UAP1 mRNA
CTD
PMID:20080153
NCBI chr13:82,342,946...82,377,558
Ensembl chr13:82,342,946...82,377,469
G
Ubap1
ubiquitin-associated protein 1
decreases expression
EXP
Ketamine results in decreased expression of UBAP1 mRNA
CTD
PMID:20080153
NCBI chr 5:56,520,722...56,561,153
Ensembl chr 5:56,520,743...56,561,152
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Ubap2
ubiquitin-associated protein 2
decreases expression
EXP
Ketamine results in decreased expression of UBAP2 mRNA
CTD
PMID:20080153
NCBI chr 5:56,348,243...56,437,403
Ensembl chr 5:56,348,246...56,437,049
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Ube2b
ubiquitin-conjugating enzyme E2B
increases expression
EXP
Ketamine results in increased expression of UBE2B mRNA
CTD
PMID:20080153
NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665
G
Ubqln1
ubiquilin 1
decreases expression
EXP
Ketamine results in decreased expression of UBQLN1 mRNA
CTD
PMID:20080153
NCBI chr17:6,439,002...6,477,096
Ensembl chr17:6,439,002...6,477,090
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Ugdh
UDP-glucose 6-dehydrogenase
decreases expression
EXP
Ketamine results in decreased expression of UGDH mRNA
CTD
PMID:20080153
NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
G
Unc5c
unc-5 netrin receptor C
decreases expression
EXP
Ketamine results in decreased expression of UNC5C mRNA
CTD
PMID:20080153
NCBI chr 2:230,180,353...230,535,219
Ensembl chr 2:230,180,951...230,535,217
G
Usp2
ubiquitin specific peptidase 2
increases expression
EXP
Ketamine results in increased expression of USP2 mRNA
CTD
PMID:20080153
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
G
Usp43
ubiquitin specific peptidase 43
decreases expression
EXP
Ketamine results in decreased expression of USP43 mRNA
CTD
PMID:20080153
NCBI chr10:52,549,200...52,611,168
Ensembl chr10:52,548,963...52,611,533
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Utp6
UTP6 small subunit processome component
decreases expression
EXP
Ketamine results in decreased expression of UTP6 mRNA
CTD
PMID:20080153
NCBI chr10:64,897,321...64,927,997
Ensembl chr10:64,897,328...64,927,997
G
Vcam1
vascular cell adhesion molecule 1
multiple interactions
ISO
[Ketamine co-treated with Atropine] inhibits the reaction [Soman results in increased expression of VCAM1 mRNA]
CTD
PMID:22245128
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
G
Vcan
versican
decreases expression
EXP
Ketamine results in decreased expression of VCAN mRNA
CTD
PMID:20080153
NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
G
Vcpip1
valosin containing protein interacting protein 1
decreases expression
EXP
Ketamine results in decreased expression of VCPIP1 mRNA
CTD
PMID:20080153
NCBI chr 5:9,534,247...9,560,889
Ensembl chr 5:9,534,129...9,562,040
G
Vdac2
voltage-dependent anion channel 2
increases expression
EXP
Ketamine results in increased expression of VDAC2 protein
CTD
PMID:18504422
NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
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Vim
vimentin
increases expression multiple interactions
ISO EXP
Ketamine results in increased expression of VIM mRNA 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride inhibits the reaction [Ketamine results in increased expression of VIM protein]
CTD
PMID:28331066
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vps13a
vacuolar protein sorting 13 homolog A
decreases expression
EXP
Ketamine results in decreased expression of VPS13A mRNA
CTD
PMID:20080153
NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555
G
Vps36
vacuolar protein sorting 36 homolog
decreases expression
EXP
Ketamine results in decreased expression of VPS36 mRNA
CTD
PMID:20080153
NCBI chr16:69,810,404...69,834,789
Ensembl chr16:69,808,193...69,834,810
G
Washc3
WASH complex subunit 3
decreases expression
EXP
Ketamine results in decreased expression of WASHC3 mRNA
CTD
PMID:20080153
NCBI chr 7:22,621,078...22,665,550
Ensembl chr 7:22,621,078...22,690,696
G
Wdr36
WD repeat domain 36
decreases expression
EXP
Ketamine results in decreased expression of WDR36 mRNA
CTD
PMID:20080153
NCBI chr18:24,473,657...24,501,773
Ensembl chr18:24,473,663...24,508,092
G
Wdr47
WD repeat domain 47
decreases expression
EXP
Ketamine results in decreased expression of WDR47 mRNA
CTD
PMID:20080153
NCBI chr 2:196,226,757...196,287,739
Ensembl chr 2:196,205,238...196,287,739
G
Wfdc6a
WAP four-disulfide core domain 6A
increases expression
EXP
Ketamine results in increased expression of WFDC6A mRNA
CTD
PMID:20080153
NCBI chr 3:153,305,336...153,309,144
Ensembl chr 3:153,305,336...153,309,144
G
Wfs1
wolframin ER transmembrane glycoprotein
increases expression
EXP
Ketamine results in increased expression of WFS1 mRNA
CTD
PMID:20080153
NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
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Wrn
WRN RecQ like helicase
decreases expression
EXP
Ketamine results in decreased expression of WRN mRNA
CTD
PMID:20080153
NCBI chr16:58,763,517...58,898,604
Ensembl chr16:58,763,504...58,895,450
G
Wtap
WT1 associated protein
increases expression
EXP
Ketamine results in increased expression of WTAP mRNA
CTD
PMID:20080153
NCBI chr 1:47,665,965...47,691,067
Ensembl chr 1:47,665,965...47,691,065
G
Xbp1
X-box binding protein 1
multiple interactions
ISO
Ketamine affects the expression of and affects the splicing of XBP1 mRNA
CTD
PMID:35728656
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
G
Xylt2
xylosyltransferase 2
increases expression
EXP
Ketamine results in increased expression of XYLT2 mRNA
CTD
PMID:20080153
NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
G
Yars2
tyrosyl-tRNA synthetase 2
decreases expression
EXP
Ketamine results in decreased expression of YARS2 mRNA
CTD
PMID:20080153
NCBI chr11:84,632,350...84,638,138
Ensembl chr11:84,624,369...84,638,125
G
Ybx3
Y box binding protein 3
decreases expression
EXP
Ketamine results in decreased expression of YBX3 mRNA
CTD
PMID:20080153
NCBI chr 4:165,129,747...165,153,101
Ensembl chr 4:165,129,758...165,153,161
G
Yjefn3
YjeF N-terminal domain containing 3
increases expression
EXP
Ketamine results in increased expression of YJEFN3 mRNA
CTD
PMID:20080153
NCBI chr16:19,533,742...19,539,759
Ensembl chr16:19,533,788...19,539,728
G
Ypel5
yippee-like 5
increases expression
EXP
Ketamine results in increased expression of YPEL5 mRNA
CTD
PMID:20080153
NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691
G
Yy1
YY1 transcription factor
decreases expression
EXP
Ketamine results in decreased expression of YY1 mRNA
CTD
PMID:20080153
NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747
G
Zbed5
zinc finger BED-type containing 5
decreases expression
EXP
Ketamine results in decreased expression of ZBED5 mRNA
CTD
PMID:20080153
NCBI chr12:26,807,652...26,813,706
Ensembl chr12:26,807,600...26,813,664
G
Zbtb8b
zinc finger and BTB domain containing 8b
decreases expression
EXP
Ketamine results in decreased expression of ZBTB8B mRNA
CTD
PMID:20080153
NCBI chr 5:141,765,925...141,781,619
Ensembl chr 5:141,766,309...141,781,600
G
Zcchc9
zinc finger CCHC-type containing 9
decreases expression
EXP
Ketamine results in decreased expression of ZCCHC9 mRNA
CTD
PMID:20080153
NCBI chr 2:23,038,156...23,048,249
Ensembl chr 2:23,038,317...23,048,217
G
Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
decreases expression
EXP
Ketamine results in decreased expression of ZDHHC23 mRNA
CTD
PMID:20080153
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
G
Zfand2a
zinc finger AN1-type containing 2A
increases expression
EXP
Ketamine results in increased expression of ZFAND2A mRNA
CTD
PMID:20080153
NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677
G
Zfhx4
zinc finger homeobox 4
decreases expression
EXP
Ketamine results in decreased expression of ZFHX4 mRNA
CTD
PMID:20080153
NCBI chr 2:96,224,763...96,408,245
Ensembl chr 2:96,224,767...96,408,228
G
Zfp36
zinc finger protein 36
increases expression
EXP
Ketamine results in increased expression of ZFP36 mRNA
CTD
PMID:20080153
NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
G
Zfp524
zinc finger protein 524
decreases expression
EXP
Ketamine results in decreased expression of ZFP524 mRNA
CTD
PMID:20080153
NCBI chr 1:68,824,803...68,828,363
Ensembl chr 1:68,824,803...68,828,594
G
Zfp57
zinc finger protein 57
decreases expression
EXP
Ketamine results in decreased expression of ZFP57 mRNA
CTD
PMID:20080153
NCBI chr20:1,521,323...1,534,884
Ensembl chr20:1,521,323...1,529,846
G
Zfp638
zinc finger protein 638
decreases expression
EXP
Ketamine results in decreased expression of ZFP638 mRNA
CTD
PMID:20080153
NCBI chr 4:116,355,934...116,475,051
Ensembl chr 4:116,402,428...116,479,845
G
Zmynd8
zinc finger, MYND-type containing 8
decreases expression
EXP
Ketamine results in decreased expression of ZMYND8 mRNA
CTD
PMID:20080153
NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463
G
Znf235-ps1
zinc finger protein 235, pseudogene 1
decreases expression
EXP
Ketamine results in decreased expression of ZFP61 mRNA
CTD
PMID:20080153
NCBI chr 1:79,799,766...79,808,543
Ensembl chr 1:79,799,769...79,808,465
G
Znhit6
zinc finger, HIT-type containing 6
decreases expression
EXP
Ketamine results in decreased expression of ZNHIT6 mRNA
CTD
PMID:20080153
NCBI chr 2:234,486,686...234,517,952
Ensembl chr 2:234,486,704...234,517,960
G
Zswim5
zinc finger, SWIM-type containing 5
decreases expression
EXP
Ketamine results in decreased expression of ZSWIM5 mRNA
CTD
PMID:20080153
NCBI chr 5:130,346,733...130,463,791
Ensembl chr 5:130,343,034...130,463,784
G
Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]
CTD
PMID:15263067
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
G
Kras
KRAS proto-oncogene, GTPase
multiple interactions
ISO
Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]
CTD
PMID:15263067
NCBI chr 4:178,185,418...178,218,484
G
Mapk1
mitogen activated protein kinase 1
decreases phosphorylation
ISO
Methohexital results in decreased phosphorylation of MAPK1 protein
CTD
PMID:15263067
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
decreases phosphorylation
ISO
Methohexital results in decreased phosphorylation of MAPK3 protein
CTD
PMID:15263067
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
G
Rac1
Rac family small GTPase 1
multiple interactions
ISO
Methohexital inhibits the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased activity of RAC1 protein]
CTD
PMID:15263067
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
G
Abhd11-as1
ABHD11 antisense RNA 1 (tail to tail)
increases expression
ISO
Propofol results in increased expression of ABHD11-AS1 mRNA
CTD
PMID:35238236
NCBI chr12:21,681,118...21,682,106
G
Acta1
actin, alpha 1, skeletal muscle
multiple interactions
EXP
HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]; Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]
CTD
PMID:24810525
NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
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Akt1
AKT serine/threonine kinase 1
multiple interactions decreases phosphorylation increases phosphorylation
EXP ISO
Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein] CASC9 protein inhibits the reaction [Propofol results in decreased phosphorylation of AKT1 protein] Propofol results in increased phosphorylation of AKT1 protein
CTD
PMID:24810525 PMID:35238236
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
G
Apaf1
apoptotic peptidase activating factor 1
decreases expression multiple interactions
EXP
Propofol results in decreased expression of APAF1 protein Propofol inhibits the reaction [Doxorubicin results in increased expression of APAF1 protein]
CTD
PMID:21468576 PMID:22015447
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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Arc
activity-regulated cytoskeleton-associated protein
multiple interactions decreases expression
EXP
Bicuculline inhibits the reaction [Propofol results in decreased expression of ARC protein]
CTD
PMID:18946287
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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Avp
arginine vasopressin
multiple interactions
ISO
[Propofol co-treated with desflurane] results in increased expression of AVP protein
CTD
PMID:8017643
NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression decreases expression
EXP ISO
[resveratrol co-treated with Propofol] results in decreased expression of BAX; Propofol inhibits the reaction [Doxorubicin results in increased expression of BAX protein] Acetylcysteine inhibits the reaction [Propofol results in increased expression of BAX protein] Propofol results in decreased expression of BAX
CTD
PMID:21786383 PMID:22015447 PMID:23353162 PMID:28804952
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bcl2
BCL2, apoptosis regulator
increases expression decreases expression multiple interactions
EXP ISO
Propofol results in increased expression of BCL2; Propofol results in increased expression of BCL2 mRNA; Propofol results in increased expression of BCL2 protein Propofol results in decreased expression of BCL2 protein Acetylcysteine inhibits the reaction [Propofol results in decreased expression of BCL2 protein] [resveratrol co-treated with Propofol] results in increased expression of BCL2; Propofol inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; Propofol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; wortmannin inhibits the reaction [Propofol results in increased expression of BCL2 protein]
CTD
PMID:19703415 PMID:21786383 PMID:22015447 PMID:23353162 PMID:24810525 PMID:28804952 More...
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1
Bcl2-like 1
decreases expression
EXP
Propofol results in decreased expression of BCL2L1 mRNA; Propofol results in decreased expression of BCL2L1 protein
CTD
PMID:26254736
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Blacat1
BLACAT1 overlapping LEMD1 locus
increases expression
ISO
Propofol results in increased expression of BLACAT1 mRNA
CTD
PMID:35238236
G
Bnip3
BCL2 interacting protein 3
multiple interactions
ISO
Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of BNIP3 mRNA]; Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of BNIP3 protein]
CTD
PMID:21307008
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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C17h10orf67
similar to human chromosome 10 open reading frame 67
increases expression
ISO
Propofol results in increased expression of C10ORF67 mRNA
CTD
PMID:35238236
NCBI chr17:82,062,461...82,174,401
Ensembl chr17:82,071,838...82,174,353
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C1h10orf143
similar to human chromosome 10 open reading frame 143
decreases expression
ISO
Propofol results in decreased expression of C10ORF143 mRNA
CTD
PMID:35238236
NCBI chr 1:192,184,440...192,222,676
Ensembl chr 1:192,184,445...192,222,398
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C3
complement C3
multiple interactions
ISO
[Triglycerides co-treated with Propofol] results in increased expression of C3 protein modified form
CTD
PMID:15983144
NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429
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Cacna1i
calcium voltage-gated channel subunit alpha1 I
affects response to substance
EXP
CACNA1I protein affects the susceptibility to Propofol
CTD
PMID:15644869
NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
G
Car1
carbonic anhydrase 1
decreases activity
ISO
Propofol analog results in decreased activity of CA1 protein; Propofol results in decreased activity of CA1 protein
CTD
PMID:19231207
NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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Car2
carbonic anhydrase 2
decreases activity
ISO
Propofol analog results in decreased activity of CA2 protein; Propofol results in decreased activity of CA2 protein
CTD
PMID:19231207
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car5a
carbonic anhydrase 5A
decreases expression
ISO
Propofol results in decreased expression of CA5A mRNA
CTD
PMID:35238236
NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906
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Casp3
caspase 3
multiple interactions increases cleavage increases expression decreases expression increases activity
EXP ISO
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole promotes the reaction [Propofol results in increased cleavage of CASP3 protein]; [Resveratrol co-treated with Propofol] results in decreased expression of CASP3; calpeptin inhibits the reaction [Propofol results in increased cleavage of CASP3 protein]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; hyperforin inhibits the reaction [Propofol results in increased cleavage of CASP3 protein]; Propofol inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]; Propofol inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Propofol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]] Acetylcysteine inhibits the reaction [Propofol results in increased cleavage of CASP3 protein] Propofol results in increased expression of CASP3 protein modified form Propofol results in decreased expression of CASP3 Propofol results in increased activity of CASP3 protein
CTD
PMID:17640472 PMID:21786383 PMID:22015447 PMID:23353162 PMID:24810525 PMID:26254736 PMID:28804952 PMID:36640868 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
decreases cleavage multiple interactions increases cleavage increases activity
EXP ISO
Propofol results in decreased cleavage of CASP9 protein Acetylcysteine inhibits the reaction [Propofol results in increased cleavage of CASP9 protein] Propofol results in increased activity of CASP9 protein
CTD
PMID:21468576 PMID:21786383 PMID:28804952
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
increases expression decreases activity multiple interactions
ISO EXP
Propofol results in increased expression of CAT protein Propofol results in decreased activity of CAT protein Acetylcysteine inhibits the reaction [Propofol results in decreased activity of CAT protein]
CTD
PMID:16938161 PMID:21468576 PMID:28804952
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Ccdc196
coiled-coil domain containing 196
affects expression
ISO
Propofol affects the expression of CCDC196 mRNA
CTD
PMID:35238236
NCBI chr 6:96,913,960...96,939,415
Ensembl chr 6:96,915,869...96,931,141
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Ccnb1
cyclin B1
decreases expression
ISO
Propofol results in decreased expression of CCNB1 protein
CTD
PMID:28804952
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnd1
cyclin D1
increases expression
ISO
Propofol results in increased expression of CCND1 protein
CTD
PMID:28804952
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Cd68
Cd68 molecule
increases expression multiple interactions
ISO
Propofol results in increased expression of CD68 mRNA Lipopolysaccharides inhibits the reaction [Propofol results in increased expression of CD68 mRNA]
CTD
PMID:35953652
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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Cdh11
cadherin 11
multiple interactions
ISO
Propofol inhibits the reaction [Lipopolysaccharides results in decreased expression of CDH11 mRNA]
CTD
PMID:35953652
NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
G
Cdk1
cyclin-dependent kinase 1
decreases expression multiple interactions
ISO
Propofol results in decreased expression of CDK1 protein [Propofol results in increased susceptibility to STA 9090] which results in decreased expression of CDK1 protein
CTD
PMID:24784839 PMID:28804952
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
G
Cdk5r1
cyclin-dependent kinase 5 regulatory subunit 1
multiple interactions increases expression
EXP
Dexmedetomidine inhibits the reaction [Propofol results in increased expression of CDK5R1 protein]
CTD
PMID:31187143
NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
G
Chrm1
cholinergic receptor, muscarinic 1
multiple interactions
EXP
Propofol inhibits the reaction [Acetylcholine results in increased activity of CHRM1 protein]; Propofol inhibits the reaction [Scopolamine Derivatives results in increased activity of CHRM1 protein]
CTD
PMID:14534362
NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
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Cxcl12
C-X-C motif chemokine ligand 12
decreases expression
ISO
Propofol results in decreased expression of CXCL12 protein
CTD
PMID:36207479
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions
ISO
Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 mRNA]
CTD
PMID:21307008
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
G
Cxcr4
C-X-C motif chemokine receptor 4
decreases expression
ISO
Propofol results in decreased expression of CXCR4 protein
CTD
PMID:36207479
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cycs
cytochrome c, somatic
increases expression
ISO
Propofol results in increased expression of CYCS protein
CTD
PMID:21786383
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases metabolic processing
ISO
CYP2B6 protein results in increased metabolism of Propofol
CTD
PMID:15769884
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Dio3os
DIO3 opposite strand upstream RNA
decreases expression
ISO
Propofol results in decreased expression of DIO3OS mRNA
CTD
PMID:35238236
G
Dpysl2
dihydropyrimidinase-like 2
increases phosphorylation multiple interactions
EXP
Propofol results in increased phosphorylation of DPYSL2 protein Dexmedetomidine inhibits the reaction [Propofol results in increased phosphorylation of DPYSL2 protein]
CTD
PMID:31187143
NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
G
Edn1
endothelin 1
decreases expression multiple interactions
EXP ISO
Propofol results in decreased expression of EDN1 protein Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium]
CTD
PMID:9138053 PMID:17470888
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
G
Egfr
epidermal growth factor receptor
multiple interactions
ISO
[Propofol results in increased susceptibility to STA 9090] which results in decreased expression of EGFR protein
CTD
PMID:24784839
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
G
Ephb2
Eph receptor B2
increases expression
ISO
Propofol results in increased expression of EPHB2 mRNA
CTD
PMID:35953652
NCBI chr 5:148,889,574...149,077,027
Ensembl chr 5:148,897,246...149,077,059
G
Ewsr1
EWS RNA-binding protein 1
increases expression
ISO
Propofol results in increased expression of EWSR1 mRNA
CTD
PMID:35953652
NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544
G
Fam95c
family with sequence similarity 95 member C
decreases expression
ISO
Propofol results in decreased expression of FAM95C mRNA
CTD
PMID:35238236
NCBI chr17:54,681,040...54,721,106
Ensembl chr17:54,681,044...54,720,740
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Fas
Fas cell surface death receptor
increases expression
ISO
Propofol results in increased expression of FAS protein
CTD
PMID:21786383
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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Fendrr
FOXF1 adjacent non-coding developmental regulatory RNA
decreases expression
ISO
Propofol results in decreased expression of FENDRR mRNA
CTD
PMID:35238236
NCBI chr19:49,127,225...49,152,780
Ensembl chr19:49,121,214...49,153,240
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Fn1
fibronectin 1
increases expression
ISO
Propofol results in increased expression of FN1 mRNA
CTD
PMID:35953652
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions increases expression
EXP
Lidocaine inhibits the reaction [Propofol results in increased expression of FOS protein] Propofol results in increased expression of FOS mRNA; Propofol results in increased expression of FOS protein
CTD
PMID:10781476 PMID:17136530
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
ISO EXP
[Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Propofol affects the reaction [Flunitrazepam binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol affects the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form] Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Propofol results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; Propofol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
CTD
PMID:9316872 PMID:10049148 PMID:11399263 PMID:12939268 PMID:22029276 PMID:29038840 More...
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
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Gabra2
gamma-aminobutyric acid type A receptor subunit alpha 2
multiple interactions
ISO
Propofol results in increased activity of [GABRA2 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA2 protein binds to GABRB3]
CTD
PMID:29038840
NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944
G
Gabra4
gamma-aminobutyric acid type A receptor subunit alpha 4
increases expression
ISO
Propofol results in increased expression of GABRA4 mRNA
CTD
PMID:16733821
NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
G
Gabra6
gamma-aminobutyric acid type A receptor subunit alpha6
multiple interactions
ISO
Propofol results in increased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]
CTD
PMID:29038840
NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769
G
Gabrb1
gamma-aminobutyric acid type A receptor subunit beta1
multiple interactions
ISO
Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; Propofol results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]
CTD
PMID:10049148 PMID:29038840
NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
G
Gabrb2
gamma-aminobutyric acid type A receptor subunit beta 2
affects response to substance multiple interactions
EXP ISO
GABRB2 protein affects the susceptibility to Propofol Propofol results in increased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA2 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form] Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Propofol results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; Propofol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
CTD
PMID:11399263 PMID:12939268 PMID:29038840
NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
G
Gabrb3
gamma-aminobutyric acid type A receptor subunit beta 3
multiple interactions
ISO
[Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Propofol affects the reaction [Flunitrazepam binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol affects the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol results in increased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA2 protein binds to GABRB3]; Propofol results in increased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form]
CTD
PMID:9316872 PMID:22029276 PMID:29038840
NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
G
Gabre
gamma-aminobutyric acid type A receptor subunit epsilon
multiple interactions decreases response to substance
ISO EXP
Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]] GABRE protein results in decreased susceptibility to Propofol
CTD
PMID:9039914 PMID:10049148
NCBI chr X:150,060,035...150,078,773
Ensembl chr X:150,060,040...150,078,693
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
ISO EXP
[Propofol co-treated with Pentobarbital] promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; delta-hexachlorocyclohexane inhibits the reaction [Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Propofol affects the reaction [Flunitrazepam binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol affects the reaction [Muscimol binds to [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]; Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Propofol results in increased activity of [GABRA1 protein binds to GABRB1 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA1 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA1 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA2 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA2 protein binds to GABRB3 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA6 protein binds to GABRB2 binds to GABRG2 protein alternative form]; Propofol results in increased activity of [GABRA6 protein binds to GABRB3 binds to GABRG2 protein alternative form] Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Propofol results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]; Propofol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]
CTD
PMID:9316872 PMID:10049148 PMID:11399263 PMID:12939268 PMID:22029276 PMID:29038840 More...
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
G
Gas5
growth arrest specific 5
increases expression
ISO
Propofol results in increased expression of GAS5 mRNA
CTD
PMID:35238236
NCBI chr13:73,303,611...73,306,932
G
Gcnt4
glucosaminyl (N-acetyl) transferase 4
increases expression
ISO
Propofol results in increased expression of GCNT4 mRNA
CTD
PMID:35238236
NCBI chr 2:28,253,325...28,283,082
Ensembl chr 2:28,252,860...28,283,082
G
Glud1
glutamate dehydrogenase 1
decreases expression
ISO
Propofol results in decreased expression of GLUD1 protein
CTD
PMID:36207479
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Gnai2
G protein subunit alpha i2
decreases expression
ISO
Propofol results in decreased expression of GNAI2 mRNA
CTD
PMID:35238236
NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
G
Gnrh1
gonadotropin releasing hormone 1
increases expression multiple interactions
ISO
Propofol results in increased expression of GNRH1 mRNA Lipopolysaccharides promotes the reaction [Propofol results in increased expression of GNRH1 mRNA]
CTD
PMID:35953652
NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581 Ensembl chr15:41,972,905...41,973,581
G
Gria2
glutamate ionotropic receptor AMPA type subunit 2
increases expression multiple interactions
EXP
Propofol results in increased expression of GRIA2 protein alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Propofol results in increased expression of GRIA2 protein]
CTD
PMID:28663055
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
G
Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
affects response to substance
ISO
GRIN2A protein affects the susceptibility to Propofol
CTD
PMID:15731593
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
G
Gsk3b
glycogen synthase kinase 3 beta
multiple interactions
EXP
Dexmedetomidine inhibits the reaction [Propofol results in decreased phosphorylation of and results in increased activity of GSK3B protein]; Propofol results in decreased phosphorylation of and results in increased activity of GSK3B protein
CTD
PMID:31187143
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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H19
H19 imprinted maternally expressed transcript
decreases expression
ISO
Propofol results in decreased expression of H19 mRNA
CTD
PMID:35238236
NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
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Hgf
hepatocyte growth factor
multiple interactions
ISO
Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of HGF mRNA]
CTD
PMID:35953652
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions decreases expression
ISO
Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A mRNA]; Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of HIF1A protein] Propofol results in decreased expression of HIF1A protein
CTD
PMID:21307008 PMID:36207479
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hmox1
heme oxygenase 1
increases expression multiple interactions
EXP
Propofol results in increased expression of HMOX1 protein HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]; HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]; Propofol inhibits the reaction [Glucose results in decreased activity of HMOX1 protein]; Propofol inhibits the reaction [Streptozocin results in decreased activity of HMOX1 protein]; Propofol promotes the reaction [Glucose results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased activity of HMOX1 protein]]; zinc protoporphyrin inhibits the reaction [Propofol promotes the reaction [Glucose results in increased expression of HMOX1 protein]]
CTD
PMID:21468576 PMID:24810525
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hpse
heparanase
increases expression multiple interactions
ISO
Propofol results in increased expression of HPSE mRNA Lipopolysaccharides promotes the reaction [Propofol results in increased expression of HPSE mRNA]
CTD
PMID:35953652
NCBI chr14:8,896,593...8,937,011
Ensembl chr14:8,896,593...8,937,010
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Htatip2
HIV-1 Tat interactive protein 2
multiple interactions increases expression
ISO
Lipopolysaccharides promotes the reaction [Propofol results in increased expression of HTATIP2 mRNA]
CTD
PMID:35953652
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
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Igf1
insulin-like growth factor 1
increases expression
ISO
Propofol results in increased expression of IGF1 mRNA
CTD
PMID:35953652
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igsf9b
immunoglobulin superfamily, member 9B
decreases expression
ISO
Propofol results in decreased expression of IGSF9B mRNA
CTD
PMID:35238236
NCBI chr 8:25,712,644...25,769,481
Ensembl chr 8:25,712,644...25,758,554
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Il10
interleukin 10
increases expression
ISO
Propofol results in increased expression of IL10 protein
CTD
PMID:17032661
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il18
interleukin 18
multiple interactions increases expression
ISO
Lipopolysaccharides promotes the reaction [Propofol results in increased expression of IL18 mRNA]
CTD
PMID:35953652
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il1b
interleukin 1 beta
multiple interactions decreases expression
ISO
Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] Propofol results in decreased expression of IL1B mRNA
CTD
PMID:35953652
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il2ra
interleukin 2 receptor subunit alpha
decreases secretion
ISO
Propofol results in decreased secretion of IL2RA protein
CTD
PMID:16119599
NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
G
Il6
interleukin 6
decreases expression multiple interactions
ISO
Propofol results in decreased expression of IL6 protein Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD
PMID:17032661 PMID:21307008
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Jak2
Janus kinase 2
decreases phosphorylation
ISO
Propofol decreases phosphorylation of JAK2 protein in colon epithelium
RGD
PMID:32386021
RGD:125097524
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
EXP
Propofol results in increased expression of JUN mRNA
CTD
PMID:10781476
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Kng1
kininogen 1
multiple interactions
ISO
[Propofol co-treated with Pharmaceutical Vehicles] results in increased expression of KNG1 protein modified form; [Triglycerides co-treated with Propofol] results in increased expression of KNG1 protein modified form; Lidocaine inhibits the reaction [[Propofol co-treated with Pharmaceutical Vehicles] results in increased expression of KNG1 protein modified form]; nafamostat inhibits the reaction [[Propofol co-treated with Pharmaceutical Vehicles] results in increased expression of KNG1 protein modified form]
CTD
PMID:10655909 PMID:15983144
NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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Ldha
lactate dehydrogenase A
increases activity
ISO
Propofol increases activity of LDHA protein in colon epithelium
RGD
PMID:32386021
RGD:125097524
NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
G
Lrcol1
leucine rich colipase-like 1
decreases expression
ISO
Propofol results in decreased expression of LRCOL1 mRNA
CTD
PMID:35238236
NCBI chr12:46,326,049...46,339,475
Ensembl chr12:46,326,077...46,337,953
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Lrg1
leucine-rich alpha-2-glycoprotein 1
increases expression
ISO
Propofol results in increased expression of LRG1 mRNA
CTD
PMID:21786383
NCBI chr 9:947,516...949,773
Ensembl chr 9:947,516...949,813
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Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
ISO
Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAP2K1 protein]
CTD
PMID:19573522
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
G
Map2k2
mitogen activated protein kinase kinase 2
multiple interactions
ISO
Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAP2K2 protein]
CTD
PMID:19573522
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
G
Mapk1
mitogen activated protein kinase 1
multiple interactions decreases phosphorylation
ISO
Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAPK1 protein] Propofol results in decreased phosphorylation of MAPK1 protein
CTD
PMID:19573522 PMID:36207479
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
G
Mapk3
mitogen activated protein kinase 3
multiple interactions decreases phosphorylation
ISO
Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of MAPK3 protein] Propofol results in decreased phosphorylation of MAPK3 protein
CTD
PMID:19573522 PMID:36207479
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Met
MET proto-oncogene, receptor tyrosine kinase
multiple interactions increases expression
ISO
Lipopolysaccharides promotes the reaction [Propofol results in increased expression of MET mRNA]
CTD
PMID:35953652
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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Mgat5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
multiple interactions increases expression
ISO
Lipopolysaccharides promotes the reaction [Propofol results in increased expression of MGAT5 mRNA]
CTD
PMID:35953652
NCBI chr13:38,675,776...38,959,697
Ensembl chr13:38,676,119...38,959,513
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Mir1224
microRNA 1224
increases expression
EXP
Propofol results in increased expression of MIR1224 mRNA
CTD
PMID:26254736
NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986
G
Mir146a
microRNA 146a
decreases expression
EXP
Propofol results in decreased expression of MIR146A mRNA
CTD
PMID:26254736
NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
G
Mir146b
microRNA 146b
decreases expression
EXP
Propofol results in decreased expression of MIR146B mRNA
CTD
PMID:26254736
NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
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Mir155
microRNA 155
decreases expression
EXP
Propofol results in decreased expression of MIR155 mRNA
CTD
PMID:26254736
NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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Mir221
microRNA 221
decreases expression
EXP
Propofol results in decreased expression of MIR221 mRNA
CTD
PMID:26254736
NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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Mir222
microRNA 222
decreases expression
EXP
Propofol results in decreased expression of MIR222 mRNA
CTD
PMID:26254736
NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
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Mir27b
microRNA 27b
increases expression
EXP
Propofol results in increased expression of MIR27B mRNA
CTD
PMID:26254736
NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
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Mir3473
microRNA 3473
increases expression
EXP
Propofol results in increased expression of MIR3473 mRNA
CTD
PMID:26254736
NCBI chr13:39,499,246...39,499,312
Ensembl chr13:39,499,246...39,499,312
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Mir378
microRNA 378
increases expression
EXP
Propofol results in increased expression of MIR378 mRNA
CTD
PMID:26254736
NCBI chr18:54,858,559...54,858,623
G
Mir6215
microRNA 6215
increases expression
EXP
Propofol results in increased expression of MIR6215 mRNA
CTD
PMID:26254736
NCBI chr 5:151,850,759...151,850,825
Ensembl chr 5:151,850,759...151,850,825
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Mir665
microRNA 665
increases expression
EXP
Propofol results in increased expression of MIR665 mRNA
CTD
PMID:26254736
NCBI chr 6:128,539,440...128,539,533
Ensembl chr 6:128,539,440...128,539,533
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Mir99a
microRNA 99a
increases expression
EXP
Propofol results in increased expression of MIR99A mRNA
CTD
PMID:26254736
NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
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Mki67
marker of proliferation Ki-67
decreases expression
ISO
Propofol results in decreased expression of MKI67 protein
CTD
PMID:36207479
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mmp2
matrix metallopeptidase 2
multiple interactions decreases expression
ISO
Lipopolysaccharides inhibits the reaction [Propofol results in decreased expression of MMP2 mRNA]
CTD
PMID:35953652
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp24os
MMP24 opposite strand
decreases expression
ISO
Propofol results in decreased expression of MMP24OS mRNA
CTD
PMID:35238236
NCBI chr 3:144,322,936...144,324,449
G
Mmp7
matrix metallopeptidase 7
multiple interactions increases expression
ISO
Lipopolysaccharides promotes the reaction [Propofol results in increased expression of MMP7 mRNA]
CTD
PMID:35953652
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
G
Mpc1
mitochondrial pyruvate carrier 1
decreases expression
ISO
Propofol results in decreased expression of MPC1 protein
CTD
PMID:36207479
NCBI chr 1:52,437,745...52,449,399
Ensembl chr 1:52,437,741...52,449,400
G
Mtor
mechanistic target of rapamycin kinase
decreases phosphorylation multiple interactions
ISO
Propofol results in decreased phosphorylation of MTOR protein CASC9 protein inhibits the reaction [Propofol results in decreased phosphorylation of MTOR protein]
CTD
PMID:35238236
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
G
Nfkbia
NFKB inhibitor alpha
multiple interactions
EXP
Propofol inhibits the reaction [Halothane results in increased phosphorylation of NFKBIA protein]
CTD
PMID:16965849
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
G
Ngf
nerve growth factor
multiple interactions
EXP
Bicuculline inhibits the reaction [Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]; Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]
CTD
PMID:11991087
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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Nos2
nitric oxide synthase 2
multiple interactions
EXP ISO
Propofol inhibits the reaction [Halothane results in increased expression of NOS2 protein] Propofol inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 mRNA]; Propofol inhibits the reaction [lipoteichoic acid results in increased expression of NOS2 protein]
CTD
PMID:16965849 PMID:19573522
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nppa
natriuretic peptide A
multiple interactions
EXP
HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]; Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]
CTD
PMID:24810525
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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Npy
neuropeptide Y
multiple interactions
EXP
Propofol inhibits the reaction [Potassium results in increased secretion of NPY protein]
CTD
PMID:29320738
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
G
Or5ac16
olfactory receptor family 5 subfamily AC member 16
decreases expression
ISO
Propofol results in decreased expression of OR5AC16 mRNA
CTD
PMID:21786383
G
Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
[Propofol results in increased susceptibility to STA 9090] which results in increased cleavage of PARP1 protein
CTD
PMID:24784839
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pcna
proliferating cell nuclear antigen
decreases expression multiple interactions
ISO
Propofol results in decreased expression of PCNA protein CASC9 protein inhibits the reaction [Propofol results in decreased expression of PCNA protein]
CTD
PMID:35238236
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
G
Pkd1l3
polycystin 1 like 3, transient receptor potential channel interacting
decreases expression
ISO
Propofol results in decreased expression of PKD1L3 mRNA
CTD
PMID:35238236
NCBI chr19:37,585,564...37,650,083
Ensembl chr19:37,585,725...37,650,155
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Pla2g2c
phospholipase A2, group IIC
increases expression
ISO
Propofol results in increased expression of PLA2G2C mRNA
CTD
PMID:35238236
NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377
G
Pln
phospholamban
decreases phosphorylation
EXP
Propofol results in decreased phosphorylation of PLN protein
CTD
PMID:27495954
NCBI chr20:32,629,537...32,639,559
G
Pnn
pinin, desmosome associated protein
multiple interactions decreases expression
ISO
Lipopolysaccharides inhibits the reaction [Propofol results in decreased expression of PNN mRNA]
CTD
PMID:35953652
NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889
G
Prkcd
protein kinase C, delta
multiple interactions
EXP
Propofol inhibits the reaction [Doxorubicin results in increased cleavage of PRKCD protein]
CTD
PMID:22015447
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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Prl
prolactin
increases secretion
ISO
Propofol results in increased secretion of PRL protein
CTD
PMID:18482853
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Pten
phosphatase and tensin homolog
increases expression multiple interactions
ISO
Propofol results in increased expression of PTEN protein CASC9 protein inhibits the reaction [Propofol results in increased expression of PTEN protein]
CTD
PMID:35238236
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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Raf1
Raf-1 proto-oncogene, serine/threonine kinase
multiple interactions
ISO
Propofol inhibits the reaction [lipoteichoic acid results in increased phosphorylation of RAF1 protein]
CTD
PMID:19573522
NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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Ren
renin
multiple interactions
ISO
[Propofol co-treated with desflurane] results in increased expression of REN protein
CTD
PMID:8017643
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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Rnu12
RNA, U12 small nuclear
decreases expression
ISO
Propofol results in decreased expression of RNU12 mRNA
CTD
PMID:35238236
NCBI chr 7:114,303,546...114,303,696
Ensembl chr 7:114,303,546...114,303,696
G
Rorb
RAR-related orphan receptor B
multiple interactions decreases expression
ISO
Lipopolysaccharides inhibits the reaction [Propofol results in decreased expression of RORB mRNA]
CTD
PMID:35953652
NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390
G
Rpsa
ribosomal protein SA
increases expression multiple interactions
ISO
Propofol results in increased expression of RPSA mRNA Lipopolysaccharides promotes the reaction [Propofol results in increased expression of RPSA mRNA]
CTD
PMID:35953652
NCBI chr 8:119,851,225...119,855,103
Ensembl chr 8:119,851,225...119,855,247
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Ryr2
ryanodine receptor 2
decreases phosphorylation
EXP
Propofol results in decreased phosphorylation of RYR2 protein
CTD
PMID:27495954
NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
G
Serpinf1
serpin family F member 1
increases expression
ISO
Propofol results in increased expression of SERPINF1 protein
CTD
PMID:36207479
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
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Set
Set nuclear proto-oncogene
decreases expression multiple interactions
ISO
Propofol results in decreased expression of SET mRNA Lipopolysaccharides inhibits the reaction [Propofol results in decreased expression of SET mRNA]
CTD
PMID:35953652
NCBI chr 3:13,334,564...13,345,598
Ensembl chr 3:13,335,041...13,363,567
G
Slc1a1
solute carrier family 1 member 1
multiple interactions
EXP
[Tetradecanoylphorbol Acetate co-treated with Propofol] inhibits the reaction [tert-Butylhydroperoxide results in decreased activity of SLC1A1 protein]
CTD
PMID:17382927
NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
G
Slc2a1
solute carrier family 2 member 1
decreases expression
ISO
Propofol results in decreased expression of SLC2A1 protein
CTD
PMID:36207479
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
G
Slc38a3
solute carrier family 38, member 3
decreases expression
ISO
Propofol results in decreased expression of SLC38A3 mRNA
CTD
PMID:35238236
NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
G
Slc6a3
solute carrier family 6 member 3
decreases expression
ISO
Propofol results in decreased expression of SLC6A3 protein
CTD
PMID:32612007
NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
G
Slc7a11
solute carrier family 7 member 11
decreases expression multiple interactions
EXP
Propofol results in decreased expression of SLC7A11 protein alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid inhibits the reaction [Propofol results in decreased expression of SLC7A11 protein]
CTD
PMID:28663055
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Smad2
SMAD family member 2
multiple interactions decreases expression
ISO
Lipopolysaccharides inhibits the reaction [Propofol results in decreased expression of SMAD2 mRNA]
CTD
PMID:35953652
NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
G
Snap25
synaptosome associated protein 25
multiple interactions
EXP
SNAP25 protein affects the reaction [Propofol affects the localization of STX1A protein]
CTD
PMID:29320738
NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760
G
Sod1
superoxide dismutase 1
multiple interactions
EXP
Propofol inhibits the reaction [Doxorubicin results in decreased expression of SOD1 protein]
CTD
PMID:22015447
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
G
Sod2
superoxide dismutase 2
increases expression multiple interactions
EXP
Propofol results in increased expression of SOD2 protein Propofol inhibits the reaction [Doxorubicin results in decreased expression of SOD2 protein]
CTD
PMID:21468576 PMID:22015447
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Src
SRC proto-oncogene, non-receptor tyrosine kinase
increases expression
ISO
Propofol results in increased expression of SRC mRNA
CTD
PMID:35953652
NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
G
Srd5a2
steroid 5 alpha-reductase 2
decreases expression
ISO
Propofol results in decreased expression of SRD5A2 mRNA
CTD
PMID:35238236
NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112
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Stat3
signal transducer and activator of transcription 3
multiple interactions decreases phosphorylation increases phosphorylation
EXP ISO
HMOX1 protein affects the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]]; Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased cleavage of CASP3 protein]]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of ACTA1 mRNA]]; STAT3 protein affects the reaction [Propofol inhibits the reaction [Glucose results in increased expression of NPPA mRNA]]; zinc protoporphyrin inhibits the reaction [Propofol inhibits the reaction [Glucose results in decreased phosphorylation of STAT3 protein]] Propofol decreases phosphorylation of STAT3 protein in colon epithelium Propofol results in increased phosphorylation of STAT3 protein
CTD RGD
PMID:24810525 PMID:32386021
RGD:125097524
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
G
Stx1a
syntaxin 1A
multiple interactions affects localization
EXP
Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]; SNAP25 protein affects the reaction [Propofol affects the localization of STX1A protein]; STX1A protein modified form inhibits the reaction [Propofol affects the localization of STX1A protein]; STX1A protein modified form inhibits the reaction [Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]]
CTD
PMID:29320738
NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
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Tdh
L-threonine dehydrogenase
decreases expression
ISO
Propofol results in decreased expression of TDH mRNA
CTD
PMID:21786383
NCBI chr15:37,739,823...37,753,365
Ensembl chr15:37,739,823...37,753,365
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Th
tyrosine hydroxylase
decreases expression
ISO
Propofol results in decreased expression of TH protein
CTD
PMID:32612007
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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Timp2
TIMP metallopeptidase inhibitor 2
increases expression multiple interactions
ISO
Propofol results in increased expression of TIMP2 mRNA; Propofol results in increased expression of TIMP2 protein Lipopolysaccharides promotes the reaction [Propofol results in increased expression of TIMP2 mRNA]
CTD
PMID:35953652
NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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Tincr
TINCR ubiquitin domain containing
increases expression
ISO
Propofol results in increased expression of TINCR mRNA
CTD
PMID:35238236
NCBI chr 9:1,387,105...1,389,337
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Tlr4
toll-like receptor 4
multiple interactions
ISO
Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 mRNA]; Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]; TLR4 protein affects the reaction [Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
CTD
PMID:19433076
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tmc6
transmembrane channel like 6
increases expression
ISO
Propofol results in increased expression of TMC6 mRNA
CTD
PMID:35238236
NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960
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Tnf
tumor necrosis factor
multiple interactions
ISO
Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; TLR4 protein affects the reaction [Propofol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]]
CTD
PMID:19433076 PMID:21307008
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tp53
tumor protein p53
multiple interactions increases expression
EXP ISO
Propofol inhibits the reaction [Doxorubicin results in increased expression of TP53 protein] Propofol results in increased expression of TP53 protein
CTD
PMID:22015447 PMID:28804952
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Trpc6
transient receptor potential cation channel, subfamily C, member 6
decreases expression multiple interactions
EXP
Propofol results in decreased expression of TRPC6 protein 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole promotes the reaction [Propofol results in decreased expression of TRPC6 protein]; hyperforin inhibits the reaction [Propofol results in decreased expression of TRPC6 protein]
CTD
PMID:36640868
NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
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Ugt1a7c
UDP glucuronosyltransferase 1 family, polypeptide A7C
increases glucuronidation
EXP
UGT1A7 protein results in increased glucuronidation of Propofol
CTD
PMID:15502008
NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a9
UDP glucuronosyltransferase family 1 member A9
decreases activity multiple interactions increases glucuronidation affects metabolic processing
ISO
Propofol results in decreased activity of UGT1A9 protein [Warfarin binds to and affects the activity of UGT1A9 protein] which affects the glucuronidation of Propofol; licochalcone A inhibits the reaction [UGT1A9 protein results in increased glucuronidation of Propofol]; shikonin inhibits the reaction [UGT1A9 protein results in increased glucuronidation of Propofol]; Warfarin affects the reaction [UGT1A9 protein results in increased glucuronidation of Propofol] UGT1A9 protein affects the metabolism of Propofol
CTD
PMID:12756209 PMID:14570768 PMID:15286053 PMID:15378558 PMID:15769885 PMID:15988124 PMID:18816295 PMID:25393417 PMID:26875642 PMID:31128210 More...
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Uhrf1
ubiquitin-like with PHD and ring finger domains 1
increases expression
ISO
Propofol results in increased expression of UHRF1 mRNA
CTD
PMID:35238236
NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
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Xist
X inactive specific transcript
increases expression
ISO
Propofol results in increased expression of XIST mRNA
CTD
PMID:35238236
NCBI chr X:68,474,987...68,492,500
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Casp3
caspase 3
multiple interactions
EXP
[Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]]; [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP3 protein modified form]]; MIR205 mRNA inhibits the reaction [Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]]; Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]; Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP3 protein modified form]
CTD
PMID:34078833
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
multiple interactions increases phosphorylation
EXP
Ketamine inhibits the reaction [remifentanil results in increased phosphorylation of GRIN2B protein]
CTD
PMID:20042082
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Htr3a
5-hydroxytryptamine receptor 3A
affects activity
ISO
remifentanil affects the activity of HTR3A protein
CTD
PMID:18635474
NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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Mir205
microRNA 205
multiple interactions
EXP
[Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]]; [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PINK1 protein]]; [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CASP3 protein modified form]]; [Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MIR205 mRNA]]; [Antagomirs results in decreased expression of MIR205 mRNA] which results in increased susceptibility to Remifentanil; MIR205 mRNA inhibits the reaction [Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of CASP3 protein modified form]]; Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in increased expression of MIR205 mRNA]; Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of MIR205 mRNA]
CTD
PMID:34078833
NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
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Pink1
PTEN induced kinase 1
multiple interactions
EXP
[Antagomirs results in decreased expression of MIR205 mRNA] promotes the reaction [Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PINK1 protein]]; Remifentanil inhibits the reaction [[Oxygen co-treated with Dithionite] results in decreased expression of PINK1 protein]; Remifentanil inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of PINK1 protein]
CTD
PMID:34078833
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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Prkcg
protein kinase C, gamma
multiple interactions affects localization
EXP
Lidocaine inhibits the reaction [remifentanil affects the localization of PRKCG protein]
CTD
PMID:19955894
NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
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Htr3a
5-hydroxytryptamine receptor 3A
affects activity
ISO
Sufentanil affects the activity of HTR3A protein
CTD
PMID:18635474
NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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Pomc
proopiomelanocortin
decreases expression
ISO
Sufentanil results in decreased expression of POMC protein modified form
CTD
PMID:15714323
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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Agt
angiotensinogen
increases expression
ISO
Thiopental results in increased expression of AGT protein
CTD
PMID:6349867
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Cacna1i
calcium voltage-gated channel subunit alpha1 I
affects response to substance
EXP
CACNA1I protein affects the susceptibility to Thiopental
CTD
PMID:15644869
NCBI chr 7:111,835,996...111,947,418
Ensembl chr 7:111,836,012...111,944,688
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Casp3
caspase 3
increases activity multiple interactions
ISO
Thiopental results in increased activity of CASP3 protein Thiopental inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]
CTD
PMID:16129983 PMID:18218830
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Chrm3
cholinergic receptor, muscarinic 3
multiple interactions
ISO
Thiopental binds to and results in decreased activity of CHRM3 protein; Thiopental inhibits the reaction [Scopolamine Derivatives binds to CHRM3 protein]
CTD
PMID:12456425
NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
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Chuk
component of inhibitor of nuclear factor kappa B kinase complex
multiple interactions
ISO
Thiopental affects the reaction [TNF protein results in increased activity of CHUK protein]
CTD
PMID:12883408
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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Gria2
glutamate ionotropic receptor AMPA type subunit 2
affects response to substance
ISO
GRIA2 protein affects the susceptibility to Thiopental
CTD
PMID:10551584
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
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Hsf1
heat shock transcription factor 1
increases phosphorylation increases activity
ISO
Thiopental results in increased phosphorylation of HSF1 protein Thiopental results in increased activity of HSF1 protein
CTD
PMID:18218830
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
increases expression
ISO
Thiopental results in increased expression of HSP90AA1 mRNA
CTD
PMID:18218830
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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Hspb1
heat shock protein family B (small) member 1
increases expression
ISO
Thiopental results in increased expression of HSPB1 mRNA
CTD
PMID:18218830
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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Il1b
interleukin 1 beta
multiple interactions
EXP
Thiopental promotes the reaction [IL1B protein results in increased abundance of Nitrites]; Thiopental promotes the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Thiopental promotes the reaction [IL1B protein results in increased expression of NOS2 protein]
CTD
PMID:9436821
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il2ra
interleukin 2 receptor subunit alpha
decreases secretion
ISO
Thiopental results in decreased secretion of IL2RA protein
CTD
PMID:16119599
NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
Thiopental inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]
CTD
PMID:15263067
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Nfkbia
NFKB inhibitor alpha
decreases degradation multiple interactions
ISO
Thiopental results in decreased degradation of NFKBIA protein TNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein]
CTD
PMID:12883408
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Ngf
nerve growth factor
multiple interactions
EXP
Bicuculline inhibits the reaction [Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]; Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]
CTD
PMID:11991087
NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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Nos2
nitric oxide synthase 2
multiple interactions
EXP
Thiopental promotes the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Thiopental promotes the reaction [IL1B protein results in increased expression of NOS2 protein]
CTD
PMID:9436821
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Npy
neuropeptide Y
multiple interactions
EXP
Thiopental inhibits the reaction [Kainic Acid results in increased expression of NPY mRNA]
CTD
PMID:9427505
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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Penk
proenkephalin
multiple interactions
EXP
Thiopental inhibits the reaction [Kainic Acid results in increased expression of PENK mRNA]
CTD
PMID:9427505
NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
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Tnf
tumor necrosis factor
multiple interactions
ISO
Thiopental affects the reaction [TNF protein results in increased activity of CHUK protein]; TNF protein affects the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Thiopental] affects the phosphorylation of NFKBIA protein]
CTD
PMID:12883408
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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