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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-diethylamino-6-methylpyrimidin-4(1H)-one
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Accession:CHEBI:38844 term browser browse the term
Definition:A pyrimidone that has formula C9H15N3O.
Synonyms:related_synonym: 2-(Diethylamino)-6-methyl-1H-pyrimidin-4-one;   Formula=C9H15N3O;   InChI=1S/C9H15N3O/c1-4-12(5-2)9-10-7(3)6-8(13)11-9/h6H,4-5H2,1-3H3,(H,10,11,13);   InChIKey=NQCPECCCWDWTJJ-UHFFFAOYSA-N;   SMILES=CCN(CC)c1nc(=O)cc(C)[nH]1
 xref: Beilstein:642602;   CAS:42487-72-9



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pirimiphos-methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO pirimiphos methyl results in decreased activity of ACHE protein CTD PMID:8658539 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases activity EXP pirimiphos methyl results in decreased activity of ANPEP protein CTD PMID:9204212 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
JBrowse link
G Ar androgen receptor multiple interactions ISO pirimiphos methyl inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] CTD PMID:21310686 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Ctsc cathepsin C decreases activity
increases activity
EXP pirimiphos methyl results in decreased activity of CTSC protein
pirimiphos methyl results in increased activity of CTSC protein
CTD PMID:9204212 NCBI chr 1:142,028,386...142,059,841
Ensembl chr 1:142,028,392...142,060,387
JBrowse link
G Ctsd cathepsin D decreases activity
increases activity
EXP pirimiphos methyl results in decreased activity of CTSD protein
pirimiphos methyl results in increased activity of CTSD protein
CTD PMID:9204212 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsl cathepsin L increases activity EXP pirimiphos methyl results in increased activity of CTSL protein CTD PMID:9204212 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Dpp6 dipeptidyl peptidase like 6 decreases activity EXP pirimiphos methyl results in decreased activity of DPP6 protein CTD PMID:9204212 NCBI chr 4:7,589,386...8,508,666
Ensembl chr 4:7,591,009...8,508,532
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO pirimiphos methyl results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO pirimiphos methyl binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases activity ISO pirimiphos methyl results in increased activity of NR4A2 protein CTD PMID:20143881 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Park7 Parkinsonism associated deglycase decreases activity ISO pirimiphos methyl results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Prep prolyl endopeptidase decreases activity EXP pirimiphos methyl results in decreased activity of PREP protein CTD PMID:9204212 NCBI chr20:48,556,211...48,653,165
Ensembl chr20:48,556,280...48,654,466
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [pirimiphos methyl binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 CTD PMID:26359731 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rnpep arginyl aminopeptidase decreases activity EXP pirimiphos methyl results in decreased activity of RNPEP protein CTD PMID:9204212 NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998
JBrowse link
G Tpp1 tripeptidyl peptidase 1 decreases activity EXP pirimiphos methyl results in decreased activity of TPP1 protein CTD PMID:9204212 NCBI chr 1:160,097,984...160,104,108
Ensembl chr 1:160,096,833...160,104,129
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    role 19854
      application 19722
        NMR chemical shift reference compound 18090
          ammonia 17865
            organic amino compound 17888
              aromatic amine 15504
                aminopyrimidine 2024
                  2-diethylamino-6-methylpyrimidin-4(1H)-one 15
                    pirimiphos-methyl 15
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19880
          baryon 19880
            nucleon 19909
              atomic nucleus 19880
                atom 19909
                  main group element atom 19849
                    main group molecular entity 19849
                      s-block molecular entity 19681
                        hydrogen molecular entity 19662
                          hydrides 19167
                            inorganic hydride 18182
                              pnictogen hydride 18172
                                nitrogen hydride 18085
                                  azane 17866
                                    ammonia 17865
                                      organic amino compound 17888
                                        aromatic amine 15504
                                          aminopyrimidine 2024
                                            2-diethylamino-6-methylpyrimidin-4(1H)-one 15
                                              pirimiphos-methyl 15
paths to the root