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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-benzofurans
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Accession:CHEBI:38830 term browser browse the term
Definition:A member of the class of benzofurans consisting of a 1-benzofuran skeleton and its substituted derivatives thereof.



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(+)-alpha-viniferin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases activity
ISO alpha-viniferin inhibits the reaction [ABCC1 protein results in increased transport of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]
alpha-viniferin results in decreased activity of ABCC1 protein
CTD PMID:16827148 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Casp3 caspase 3 increases activity ISO alpha-viniferin analog results in increased activity of CASP3 protein; alpha-viniferin results in increased activity of CASP3 protein CTD PMID:16158945 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO alpha-viniferin analog results in increased activity of CASP8 protein; alpha-viniferin results in increased activity of CASP8 protein CTD PMID:16158945 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO alpha-viniferin analog results in increased activity of CASP9 protein; alpha-viniferin results in increased activity of CASP9 protein CTD PMID:16158945 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of CXCL10 mRNA]; alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of CXCL10 protein]; alpha-viniferin inhibits the reaction [IRF1 protein results in increased expression of CXCL10 mRNA]; alpha-viniferin inhibits the reaction [IRF1 protein results in increased expression of CXCL10 protein] CTD PMID:20424383 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of CXCL9 mRNA]; alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of CXCL9 protein] CTD PMID:20424383 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO alpha-viniferin results in increased expression of HMOX1 mRNA; alpha-viniferin results in increased expression of HMOX1 protein
[NFE2L2 protein results in increased expression of HMOX1] affects the reaction [alpha-viniferin results in decreased susceptibility to Lipopolysaccharides]; NFE2L2 protein affects the reaction [alpha-viniferin results in increased expression of HMOX1 mRNA]
CTD PMID:24859013 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma multiple interactions ISO alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of CXCL10 mRNA]; alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of CXCL10 protein]; alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of CXCL9 mRNA]; alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of CXCL9 protein]; alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of NOS2 protein]; alpha-viniferin inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; alpha-viniferin inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:20424383 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO alpha-viniferin inhibits the reaction [IRF1 protein results in increased expression of CXCL10 mRNA]; alpha-viniferin inhibits the reaction [IRF1 protein results in increased expression of CXCL10 protein] CTD PMID:20424383 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO alpha-viniferin inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:20424383 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO alpha-viniferin inhibits the reaction [MAPK9 protein results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:20424383 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
affects response to substance
ISO [NFE2L2 protein results in increased expression of HMOX1] affects the reaction [alpha-viniferin results in decreased susceptibility to Lipopolysaccharides]; alpha-viniferin results in increased expression of and results in increased activity of NFE2L2 protein; NFE2L2 protein affects the reaction [alpha-viniferin results in increased expression of HMOX1 mRNA]
NFE2L2 protein affects the susceptibility to alpha-viniferin
CTD PMID:24859013 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of NOS2 mRNA]; alpha-viniferin inhibits the reaction [IFNG protein results in increased expression of NOS2 protein]; alpha-viniferin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; alpha-viniferin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:14531020 PMID:20424383 PMID:24859013 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases activity ISO alpha-viniferin results in decreased activity of PTGS1 protein CTD PMID:14531020 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases activity
multiple interactions
ISO alpha-viniferin results in decreased activity of PTGS2 protein
alpha-viniferin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; alpha-viniferin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
CTD PMID:14531020 PMID:24859013 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO alpha-viniferin inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of STAT1 protein]; alpha-viniferin inhibits the reaction [MAPK9 protein results in increased phosphorylation of and results in increased activity of STAT1 protein] CTD PMID:20424383 NCBI chr 9:49,419,561...49,459,969 JBrowse link
(-)-trans-epsilon-viniferin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases activity
ISO epsilon-viniferin inhibits the reaction [ABCC1 protein results in increased transport of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]
epsilon-viniferin results in decreased activity of ABCC1 protein
CTD PMID:16827148 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO epsilon-viniferin inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of AKT1 protein] CTD PMID:34144024 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Ctsg cathepsin G multiple interactions ISO epsilon-viniferin inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased secretion of CTSG protein] CTD PMID:34144024 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO epsilon-viniferin results in decreased activity of CYP1A1 protein CTD PMID:12818727 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO epsilon-viniferin results in decreased activity of CYP1A2 protein CTD PMID:12818727 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO epsilon-viniferin results in decreased activity of CYP1B1 protein CTD PMID:12818727 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity ISO epsilon-viniferin results in decreased activity of CYP2B6 protein CTD PMID:12818727 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO epsilon-viniferin results in decreased activity of CYP2E1 protein CTD PMID:12818727 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO epsilon-viniferin results in decreased activity of CYP3A4 protein CTD PMID:12818727 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO epsilon-viniferin results in increased expression of LDLR mRNA CTD PMID:22153697 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO epsilon-viniferin inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK1 protein] CTD PMID:34144024 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO epsilon-viniferin inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of MAPK3 protein] CTD PMID:34144024 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO epsilon-viniferin inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased phosphorylation of SRC protein] CTD PMID:34144024 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
1-benzofuran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsm1 acyl-CoA synthetase medium-chain family member 1 affects expression
increases expression
ISO benzofuran affects the expression of ACSM1 mRNA
benzofuran results in increased expression of ACSM1 mRNA
CTD PMID:17114358 PMID:17311802 NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions EXP benzofuran binds to and results in increased activity of AHR protein CTD PMID:21431309 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ces1d carboxylesterase 1D affects expression
increases expression
ISO benzofuran affects the expression of CES1 mRNA
benzofuran results in increased expression of CES1 mRNA
CTD PMID:17114358 PMID:17311802 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO benzofuran analog results in decreased activity of CYP19A1 protein CTD PMID:15968818 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO benzofuran analog results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
affects expression
ISO benzofuran results in increased expression of EPHX1 mRNA
benzofuran affects the expression of EPHX1 mRNA
CTD PMID:17114358 PMID:17311802 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects expression ISO benzofuran affects the expression of GSTM1 mRNA CTD PMID:17114358 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma affects expression ISO benzofuran affects the expression of IKBKG mRNA CTD PMID:17114358 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 affects expression ISO benzofuran affects the expression of ITIH1 mRNA CTD PMID:17114358 NCBI chr16:6,122,246...6,136,363
Ensembl chr16:6,122,248...6,136,363
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO benzofuran results in increased activity of NFE2L2 protein CTD PMID:30114225 PMID:30203046 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO benzofuran results in increased expression of NQO1 mRNA CTD PMID:17311802 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO benzofuran results in increased activity of NR1I3 protein CTD PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pls1 plastin 1 affects expression ISO benzofuran affects the expression of PLS1 mRNA CTD PMID:17114358 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
increases activity
ISO benzofuran results in increased expression of PPARA mRNA
benzofuran results in increased activity of PPARA protein
CTD PMID:25689681 PMID:30203046 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Snhg11 small nucleolar RNA host gene 11 affects expression ISO benzofuran affects the expression of SNHG11 mRNA CTD PMID:17114358 NCBI chr 3:147,031,411...147,037,809 JBrowse link
G Stat5b signal transducer and activator of transcription 5B increases activity ISO benzofuran results in increased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Ttc39a tetratricopeptide repeat domain 39A affects expression ISO benzofuran affects the expression of TTC39A mRNA CTD PMID:17114358 NCBI chr 5:124,165,102...124,204,973
Ensembl chr 5:124,151,760...124,204,973
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase affects expression ISO benzofuran affects the expression of UGDH mRNA CTD PMID:17114358 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
2,3-dihydrobenzofuran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO coumaran results in decreased activity of CYP1A2 protein CTD PMID:15916432 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
amiodarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase affects expression EXP Amiodarone affects the expression of AADAT mRNA CTD PMID:18355885 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Amiodarone results in decreased expression of ABCA1 mRNA CTD PMID:29248575 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca2 ATP binding cassette subfamily A member 2 increases expression ISO Amiodarone results in increased expression of ABCA2 mRNA CTD PMID:19774075 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression
decreases activity
ISO
EXP
Amiodarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Amiodarone results in decreased expression of ABCB11 mRNA
Amiodarone results in decreased activity of ABCB11 protein
CTD PMID:20829430 PMID:24014644 PMID:27765674 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
affects expression
affects response to substance
decreases activity
ISO
EXP
Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]
Amiodarone affects the expression of ABCB1 mRNA; Amiodarone affects the expression of ABCB1A mRNA
Amiodarone inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
ABCB1A protein affects the susceptibility to Amiodarone
Amiodarone results in decreased activity of ABCB1 protein
CTD PMID:11231118 PMID:12235267 PMID:15502009 PMID:18355885 PMID:19483382 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B affects response to substance ISO ABCB1B protein affects the susceptibility to Amiodarone CTD PMID:15502009 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
decreases expression
ISO
EXP
Amiodarone results in increased expression of ABCB4 mRNA
Amiodarone results in decreased expression of ABCB4 mRNA
CTD PMID:24489787 PMID:27765674 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Amiodarone results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
ISO
EXP
Amiodarone results in increased expression of ABCC3 mRNA
Amiodarone results in decreased expression of ABCC3 mRNA
CTD PMID:24489787 PMID:27765674 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression EXP Amiodarone results in decreased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects expression EXP Amiodarone affects the expression of ABCC6 mRNA CTD PMID:19483382 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression ISO Amiodarone results in increased expression of ABCD3 mRNA CTD PMID:24489787 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 increases expression ISO Amiodarone results in increased expression of ABCD4 mRNA CTD PMID:24489787 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression
increases expression
EXP Amiodarone affects the expression of ABCG5 mRNA
Amiodarone results in increased expression of ABCG5 mRNA
CTD PMID:19483382 PMID:27765674 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression EXP Amiodarone affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression EXP Amiodarone affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Amiodarone affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Amiodarone results in increased expression of ABL1 mRNA CTD PMID:19774075 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO Amiodarone results in increased expression of ACAA1 mRNA CTD PMID:15265979 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of ACACA mRNA
Amiodarone results in increased expression of ACACA mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression EXP
ISO
Amiodarone results in increased expression of ACACB mRNA CTD PMID:19224547 PMID:24489787 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acad10 acyl-CoA dehydrogenase family, member 10 increases expression ISO Amiodarone results in increased expression of ACAD10 mRNA CTD PMID:24535564 NCBI chr12:34,901,211...34,943,973
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 increases expression ISO Amiodarone results in increased expression of ACAD9 mRNA CTD PMID:24489787 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Amiodarone affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO Amiodarone results in increased expression of ACADM mRNA CTD PMID:24489787 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression ISO Amiodarone results in increased expression of ACAT1 mRNA CTD PMID:24489787 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression EXP Amiodarone results in increased expression of ACER2 mRNA CTD PMID:25580480 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Acly ATP citrate lyase increases expression ISO Amiodarone results in increased expression of ACLY mRNA CTD PMID:32535746 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Aco1 aconitase 1 affects expression EXP Amiodarone affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 affects expression EXP Amiodarone affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO Amiodarone results in increased expression of ACOT1 mRNA CTD PMID:24489787 PMID:24535564 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of ACOT12 mRNA
Amiodarone results in increased expression of ACOT12 mRNA
CTD PMID:19483382 PMID:24489787 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Amiodarone results in increased expression of ACOT2 mRNA CTD PMID:24489787 PMID:24535564 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO Amiodarone results in increased expression of ACOT3 mRNA CTD PMID:24535564 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,723,326...103,729,482
JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression EXP Amiodarone affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
JBrowse link
G Acot8 acyl-CoA thioesterase 8 increases expression ISO Amiodarone results in increased expression of ACOT8 mRNA CTD PMID:19774075 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Amiodarone results in increased expression of ACOX1 mRNA CTD PMID:15265979 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acox2 acyl-CoA oxidase 2 increases expression ISO Amiodarone results in increased expression of ACOX2 mRNA CTD PMID:24489787 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acsf3 acyl-CoA synthetase family member 3 increases expression ISO Amiodarone results in increased expression of ACSF3 mRNA CTD PMID:19774075 NCBI chr19:50,835,116...50,875,557
Ensembl chr19:50,835,221...50,875,553
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO Amiodarone results in increased expression of ACSS2 mRNA CTD PMID:24535564 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Actr3b actin related protein 3B increases expression ISO Amiodarone results in increased expression of ACTR3B mRNA CTD PMID:19774075 NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441
JBrowse link
G Acvr1b activin A receptor type 1B increases expression ISO Amiodarone results in increased expression of ACVR1B mRNA CTD PMID:19774075 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Acyp1 acylphosphatase 1 increases expression ISO Amiodarone results in increased expression of ACYP1 mRNA CTD PMID:19774075 NCBI chr 6:104,919,162...104,932,348
Ensembl chr 6:104,919,162...104,932,387
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression EXP Amiodarone affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 2:174,754,631...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Add1 adducin 1 affects expression EXP Amiodarone affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO Amiodarone results in increased expression of ADGRD1 mRNA CTD PMID:19774075 NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO Amiodarone results in decreased expression of ADGRF1 mRNA CTD PMID:24535564 NCBI chr 9:17,661,258...17,696,359 JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Amiodarone affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Adora3 adenosine A3 receptor increases expression ISO Amiodarone results in increased expression of ADORA3 mRNA CTD PMID:19774075
G Adra2a adrenoceptor alpha 2A increases expression ISO Amiodarone results in increased expression of ADRA2A mRNA CTD PMID:19774075 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Adrb1 adrenoceptor beta 1 decreases expression ISO Amiodarone results in decreased expression of ADRB1 protein CTD PMID:1653643 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression ISO Amiodarone results in decreased expression of ADRB2 protein CTD PMID:1653643 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions EXP Amiodarone inhibits the reaction [Triiodothyronine results in decreased expression of ADRB3 protein] CTD PMID:10217540 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression EXP Amiodarone affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr17:22,930,012...22,993,834
Ensembl chr17:22,930,740...22,993,826
JBrowse link
G Afm afamin affects expression EXP Amiodarone affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr14:17,531,026...17,563,868
Ensembl chr14:17,531,024...17,563,870
JBrowse link
G Afp alpha-fetoprotein increases expression ISO Amiodarone results in increased expression of AFP mRNA CTD PMID:24489787 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Agt angiotensinogen increases expression
affects expression
multiple interactions
ISO
EXP
Amiodarone results in increased expression of AGT mRNA; Amiodarone results in increased expression of AGT protein
Amiodarone affects the expression of AGT mRNA
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD PMID:17214612 PMID:19483382 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Amiodarone affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Amiodarone results in increased expression of AHNAK mRNA CTD PMID:19774075 NCBI chr 1:205,882,223...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Amiodarone results in increased expression of AIFM1 mRNA CTD PMID:24489787 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Ak4 adenylate kinase 4 increases expression EXP Amiodarone results in increased expression of AK4 protein CTD PMID:16538043 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 affects expression EXP Amiodarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Amiodarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Amiodarone affects the expression of AKR7A3 mRNA CTD PMID:19483382 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Amiodarone results in decreased phosphorylation of AKT1 protein CTD PMID:23912912 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO Amiodarone results in increased expression of ALAS1 mRNA CTD PMID:19774075 NCBI chr 8:106,876,514...106,889,852
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression ISO Amiodarone results in decreased expression of ALAS2 mRNA CTD PMID:24535564 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Alb albumin increases expression ISO Amiodarone results in increased expression of ALB mRNA CTD PMID:19774075 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Amiodarone affects the expression of ALDH1A1 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 affects expression EXP Amiodarone affects the expression of ALDH1A4 mRNA CTD PMID:18355885 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression EXP Amiodarone affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:34,949,549...34,982,527 JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 increases expression ISO Amiodarone results in increased expression of ALDH3A2 mRNA CTD PMID:24535564 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression EXP Amiodarone results in increased expression of ALDH6A1 mRNA CTD PMID:17991464 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase increases expression ISO Amiodarone results in increased expression of ALG12 mRNA CTD PMID:19774075 NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase increases expression ISO Amiodarone results in increased expression of ALG2 mRNA CTD PMID:19774075 NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297
JBrowse link
G Alk ALK receptor tyrosine kinase increases expression ISO Amiodarone results in increased expression of ALK mRNA CTD PMID:19774075 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Alkal1 ALK and LTK ligand 1 increases expression ISO Amiodarone results in increased expression of ALKAL1 mRNA CTD PMID:19774075 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948
JBrowse link
G Alkbh7 alkB homolog 7 affects expression EXP Amiodarone affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 increases expression ISO Amiodarone results in increased expression of AMIGO1 mRNA CTD PMID:19774075 NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585
JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Amiodarone results in decreased expression of ANGPTL3 mRNA CTD PMID:27089845 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Amiodarone results in increased expression of ANGPTL4 mRNA CTD PMID:24489787 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Anxa4 annexin A4 increases expression ISO Amiodarone results in increased expression of ANXA4 mRNA CTD PMID:19774075 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression
increases expression
ISO Amiodarone results in decreased expression of AP1S1 mRNA
Amiodarone results in increased expression of AP1S1 mRNA
CTD PMID:17175557 PMID:17567588 PMID:29248575 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 affects expression EXP Amiodarone affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Apcs amyloid P component, serum affects expression EXP Amiodarone affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Amiodarone affects the expression of APOA4 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 increases expression ISO Amiodarone results in increased expression of APOA5 mRNA CTD PMID:24489787 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apob apolipoprotein B decreases expression ISO Amiodarone results in decreased expression of APOB mRNA CTD PMID:29248575 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc2 apolipoprotein C2 increases expression ISO Amiodarone results in increased expression of APOC2 mRNA CTD PMID:24489787 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoe apolipoprotein E decreases expression EXP Amiodarone results in decreased expression of APOE mRNA CTD PMID:17991464 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apoh apolipoprotein H affects expression EXP Amiodarone affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Apool apolipoprotein O-like affects expression EXP Amiodarone affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:77,377,685...77,443,670
Ensembl chr  X:77,377,781...77,443,900
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression ISO Amiodarone results in increased expression of ARC mRNA CTD PMID:19774075 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arg1 arginase 1 affects expression EXP Amiodarone affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgap15 Rho GTPase activating protein 15 increases expression ISO Amiodarone results in increased expression of ARHGAP15 mRNA CTD PMID:19774075 NCBI chr 3:27,989,368...28,592,722
Ensembl chr 3:27,989,633...28,600,265
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 increases expression ISO Amiodarone results in increased expression of ARHGAP35 mRNA CTD PMID:19774075 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298
JBrowse link
G Arhgap4 Rho GTPase activating protein 4 increases expression ISO Amiodarone results in increased expression of ARHGAP4 mRNA CTD PMID:19774075 NCBI chr  X:151,636,071...151,651,528
Ensembl chr  X:151,632,454...151,651,128
JBrowse link
G Arhgap45 Rho GTPase activating protein 45 increases expression ISO Amiodarone results in increased expression of ARHGAP45 mRNA CTD PMID:19774075 NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases expression ISO Amiodarone results in increased expression of ARHGAP9 mRNA CTD PMID:19774075 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
JBrowse link
G Arhgef10l Rho guanine nucleotide exchange factor 10 like increases expression ISO Amiodarone results in increased expression of ARHGEF10L mRNA CTD PMID:19774075 NCBI chr 5:152,792,247...152,935,255
Ensembl chr 5:152,792,252...152,919,538
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 increases expression ISO Amiodarone results in increased expression of ARHGEF7 mRNA CTD PMID:19774075 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697
JBrowse link
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 increases expression ISO Amiodarone results in increased expression of ARHGEF9 mRNA CTD PMID:19774075 NCBI chr  X:59,919,560...60,077,538
Ensembl chr  X:59,920,870...60,077,513
JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Amiodarone results in increased expression of ARID5A mRNA CTD PMID:19774075 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 affects expression EXP Amiodarone affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
JBrowse link
G Armc9 armadillo repeat containing 9 increases expression ISO Amiodarone results in increased expression of ARMC9 mRNA CTD PMID:19774075 NCBI chr 9:86,802,791...86,928,860
Ensembl chr 9:86,802,868...86,928,860
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Amiodarone results in increased expression of ARPC4 mRNA CTD PMID:19774075 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression EXP
ISO
Amiodarone results in increased expression of ASAH1 mRNA CTD PMID:15342952 PMID:17567588 PMID:19224547 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Asb7 ankyrin repeat and SOCS box-containing 7 increases expression ISO Amiodarone results in increased expression of ASB7 mRNA CTD PMID:19774075 NCBI chr 1:120,222,835...120,267,411
Ensembl chr 1:120,222,745...120,267,282
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression EXP Amiodarone affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Amiodarone results in increased expression of ASNS mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Amiodarone results in increased expression of ATF3 mRNA CTD PMID:19774075 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
ISO Amiodarone results in increased expression of ATF4 protein
Amiodarone results in increased expression of ATF4 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of ATF4 mRNA]
CTD PMID:21292685 PMID:28962527 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf5 activating transcription factor 5 affects expression EXP Amiodarone affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO Amiodarone results in increased expression of and affects the localization of ATF6 protein CTD PMID:28962527 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atf6b activating transcription factor 6 beta increases expression ISO Amiodarone results in increased expression of ATF6B mRNA CTD PMID:19774075 NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894
JBrowse link
G Atg5 autophagy related 5 affects response to substance ISO ATG5 protein affects the susceptibility to Amiodarone CTD PMID:32651653 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 increases expression
affects response to substance
multiple interactions
ISO Amiodarone results in increased expression of ATG7 protein
ATG7 protein affects the susceptibility to Amiodarone
ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]
CTD PMID:23912912 PMID:32651653 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atoh1 atonal bHLH transcription factor 1 increases expression ISO Amiodarone results in increased expression of ATOH1 mRNA CTD PMID:19774075 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
JBrowse link
G Atp11c ATPase phospholipid transporting 11C increases expression ISO Amiodarone results in increased expression of ATP11C mRNA CTD PMID:19774075 NCBI chr  X:138,564,459...138,752,116
Ensembl chr  X:138,565,836...138,751,204
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP Amiodarone results in decreased expression of ATP1A1 protein CTD PMID:8071999 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression EXP Amiodarone results in decreased expression of ATP1A2 mRNA; Amiodarone results in decreased expression of ATP1A2 protein CTD PMID:7573397 PMID:8071999 PMID:12479229 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Amiodarone results in decreased expression of ATP1B1 protein CTD PMID:8071999 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 decreases expression EXP Amiodarone results in decreased expression of ATP1B2 mRNA CTD PMID:8071999 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression EXP Amiodarone results in decreased expression of ATP2A2 mRNA CTD PMID:17535870 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP Amiodarone results in increased expression of ATP5F1B mRNA CTD PMID:17991464 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Amiodarone affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression EXP Amiodarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP Amiodarone affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F affects expression EXP Amiodarone affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP Amiodarone affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Bag1 BAG cochaperone 1 increases expression ISO Amiodarone results in increased expression of BAG1 mRNA CTD PMID:19774075 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bag3 BAG cochaperone 3 decreases expression EXP Amiodarone results in decreased expression of BAG3 mRNA CTD PMID:17991464 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 increases expression ISO Amiodarone results in increased expression of BAIAP2L1 mRNA CTD PMID:19774075 NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Amiodarone results in increased expression of BAX mRNA CTD PMID:12084619 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 increases expression ISO Amiodarone results in increased expression of BBOX1 mRNA CTD PMID:19774075 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha increases expression EXP Amiodarone results in increased expression of BCKDHA protein CTD PMID:16538043 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
EXP
ISO
Amiodarone results in decreased expression of BCL2 protein
[3-methyladenine co-treated with Amiodarone] results in decreased expression of BCL2 protein
CTD PMID:21224497 PMID:23912912 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO Amiodarone results in increased expression of BCL2L11 mRNA CTD PMID:19774075 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression EXP Amiodarone results in increased expression of BCL3 mRNA CTD PMID:22015988 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl6b BCL6B, transcription repressor affects expression EXP Amiodarone affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Bco1 beta-carotene oxygenase 1 decreases expression ISO Amiodarone results in decreased expression of BCO1 mRNA CTD PMID:24535564 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101
JBrowse link
G Bdnf brain-derived neurotrophic factor affects expression EXP Amiodarone affects the expression of BDNF mRNA CTD PMID:31324950 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Amiodarone results in increased expression of BHLHE40 mRNA CTD PMID:19774075 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase affects expression EXP Amiodarone affects the expression of BHMT mRNA CTD PMID:18355885 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [TNFSF10 co-treated with Amiodarone] results in increased cleavage of BID protein CTD PMID:21292685 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP Amiodarone results in decreased expression of BIRC5 protein CTD PMID:21224497 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP Amiodarone affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmp2k BMP-2 inducible kinase increases expression ISO Amiodarone results in increased expression of BMP2K mRNA CTD PMID:19774075 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression EXP Amiodarone affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bola2 bolA family member 2 increases expression ISO Amiodarone results in increased expression of BOLA2 mRNA CTD PMID:19774075 NCBI chr 1:181,291,777...181,292,836
Ensembl chr 1:181,291,398...181,292,676
JBrowse link
G Boll boule homolog, RNA binding protein increases expression ISO Amiodarone results in increased expression of BOLL mRNA CTD PMID:19774075 NCBI chr 9:56,734,890...56,859,917
Ensembl chr 9:56,733,584...56,859,916
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO Amiodarone results in increased expression of BRCA1 mRNA CTD PMID:24489787 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 increases expression ISO Amiodarone results in increased expression of BRCC3 mRNA CTD PMID:19774075 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
JBrowse link
G Brpf1 bromodomain and PHD finger containing, 1 increases expression ISO Amiodarone results in increased expression of BRPF1 mRNA CTD PMID:19774075 NCBI chr 4:146,456,344...146,472,781
Ensembl chr 4:146,456,318...146,472,649
JBrowse link
G Bsg basigin (Ok blood group) increases expression ISO Amiodarone results in increased expression of BSG mRNA CTD PMID:19774075 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Btf3 basic transcription factor 3 affects expression EXP Amiodarone affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G C1qbp complement C1q binding protein affects expression EXP Amiodarone affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C1s complement C1s affects expression EXP Amiodarone affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression EXP Amiodarone affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression ISO Amiodarone results in increased expression of NLF2 mRNA CTD PMID:19774075 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
JBrowse link
G C4bpa complement component 4 binding protein, alpha affects expression EXP Amiodarone affects the expression of C4BPA mRNA CTD PMID:19483382 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C7 complement C7 affects expression EXP Amiodarone affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G C8b complement C8 beta chain affects expression
decreases expression
EXP
ISO
Amiodarone affects the expression of C8B mRNA
Amiodarone results in decreased expression of C8B mRNA
CTD PMID:19483382 PMID:24535564 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
JBrowse link
G Ca3 carbonic anhydrase 3 affects expression
increases expression
EXP Amiodarone affects the expression of CAR3 mRNA
Amiodarone results in increased expression of CAR3 protein
CTD PMID:16538043 PMID:19483382 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C decreases expression ISO Amiodarone results in decreased expression of CACNA1C mRNA CTD PMID:15520326 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects expression EXP Amiodarone affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO Amiodarone results in increased expression of CAMK2A mRNA CTD PMID:19774075 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Capn11 calpain 11 increases expression ISO Amiodarone results in increased expression of CAPN11 mRNA CTD PMID:19774075 NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601
JBrowse link
G Capn3 calpain 3 increases expression ISO Amiodarone results in increased expression of CAPN3 mRNA CTD PMID:19774075 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression EXP Amiodarone affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Amiodarone affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Card9 caspase recruitment domain family, member 9 increases expression ISO Amiodarone results in increased expression of CARD9 mRNA CTD PMID:19774075 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Caskin2 cask-interacting protein 2 increases expression ISO Amiodarone results in increased expression of CASKIN2 mRNA CTD PMID:19774075 NCBI chr10:101,027,196...101,041,429
Ensembl chr10:101,027,260...101,041,414
JBrowse link
G Casp3 caspase 3 affects expression
increases cleavage
increases activity
increases expression
decreases expression
multiple interactions
EXP
ISO
Amiodarone affects the expression of CASP3 mRNA
Amiodarone results in increased cleavage of CASP3 protein
Amiodarone results in increased activity of CASP3 protein
Amiodarone results in increased expression of CASP3 mRNA
Amiodarone results in decreased expression of CASP3 protein modified form
3-methyladenine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP3 protein; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; Amiodarone results in increased activity of and results in increased cleavage of CASP3 protein; ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]
CTD PMID:12084619 PMID:12747577 PMID:19483382 PMID:19815060 PMID:21224497 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases expression
increases activity
ISO alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]
Amiodarone results in increased expression of CASP7 mRNA
CTD PMID:23042730 PMID:23135547 PMID:24489787 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
ISO
EXP
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP8 protein
Amiodarone results in increased expression of CASP8 protein modified form
CTD PMID:21224497 PMID:21292685 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
ISO Amiodarone results in increased expression of CASP9 mRNA
[Amiodarone co-treated with TNF protein] results in increased activity of CASP9 protein
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP9 protein
CTD PMID:19774075 PMID:21292685 PMID:23042730 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP Amiodarone inhibits the reaction [Indomethacin results in increased activity of CAT protein] CTD PMID:18087811 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav3 caveolin 3 increases expression ISO Amiodarone results in increased expression of CAV3 mRNA CTD PMID:19774075 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression EXP Amiodarone affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Ccdc134 coiled-coil domain containing 134 increases expression ISO Amiodarone results in increased expression of CCDC134 mRNA CTD PMID:19774075 NCBI chr 7:113,644,557...113,659,050
Ensembl chr 7:113,644,639...113,659,050
JBrowse link
G Ccdc17 coiled-coil domain containing 17 increases expression ISO Amiodarone results in increased expression of CCDC17 mRNA CTD PMID:19774075 NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673
JBrowse link
G Ccdc9 coiled-coil domain containing 9 increases expression ISO Amiodarone results in increased expression of CCDC9 mRNA CTD PMID:19774075 NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:76,974,091...76,991,607
JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression ISO Amiodarone results in increased expression of CCDC96 mRNA CTD PMID:19774075 NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]
[Amiodarone co-treated with Dexamethasone] results in increased expression of CCL2 mRNA
Amiodarone results in increased expression of CCL2 mRNA
CTD PMID:19225199 PMID:23397585 PMID:25900201 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnt1 cyclin T1 increases expression ISO Amiodarone results in increased expression of CCNT1 mRNA CTD PMID:19774075 NCBI chr 7:129,687,146...129,718,082
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 increases expression ISO Amiodarone results in increased expression of CCR9 mRNA CTD PMID:19774075 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
JBrowse link
G Cd320 CD320 molecule increases expression ISO Amiodarone results in increased expression of CD320 mRNA CTD PMID:19774075 NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976
JBrowse link
G Cd36 CD36 molecule increases expression
decreases expression
ISO Amiodarone results in increased expression of CD36 mRNA
Amiodarone results in decreased expression of CD36 mRNA
CTD PMID:24535564 PMID:29248575 PMID:32535746 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd86 CD86 molecule multiple interactions ISO [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein CTD PMID:22785256 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cda cytidine deaminase increases expression ISO Amiodarone results in increased expression of CDA mRNA CTD PMID:24535564 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO Amiodarone results in increased expression of CDC25A mRNA CTD PMID:19774075 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc42se1 CDC42 small effector 1 increases expression ISO Amiodarone results in increased expression of CDC42SE1 mRNA CTD PMID:19774075 NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028
JBrowse link
G Cdh15 cadherin 15 increases expression ISO Amiodarone results in increased expression of CDH15 mRNA CTD PMID:19774075 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
JBrowse link
G Cdh26 cadherin 26 increases expression ISO Amiodarone results in increased expression of CDH26 mRNA CTD PMID:19774075 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149
JBrowse link
G Cdk17 cyclin-dependent kinase 17 increases expression ISO Amiodarone results in increased expression of CDK17 mRNA CTD PMID:19774075 NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression EXP Amiodarone affects the expression of CDKN2C mRNA CTD PMID:18355885 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Amiodarone affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO
EXP
Amiodarone results in increased expression of CEBPB mRNA CTD PMID:19774075 PMID:25580480 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression ISO Amiodarone results in increased expression of CELF6 mRNA CTD PMID:19774075 NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 affects expression EXP Amiodarone affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Amiodarone results in increased expression of CES1 mRNA CTD PMID:21163907 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Amiodarone affects the expression of CES2 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfi complement factor I affects expression EXP Amiodarone affects the expression of CFI mRNA CTD PMID:19483382 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression EXP Amiodarone results in decreased expression of CFLAR protein CTD PMID:21224497 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression EXP Amiodarone results in increased expression of CGA mRNA CTD PMID:3427795 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Amiodarone results in increased expression of CHAC1 mRNA CTD PMID:19774075 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression EXP Amiodarone results in decreased expression of CHAF1A mRNA CTD PMID:17991464 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP Amiodarone results in decreased expression of CHAT protein CTD PMID:25659768 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chga chromogranin A increases expression ISO Amiodarone results in increased expression of CHGA mRNA CTD PMID:19774075 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 affects expression EXP Amiodarone affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO Amiodarone results in increased expression of CHRNB3 mRNA CTD PMID:19774075 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression ISO Amiodarone results in increased expression of CHST6 mRNA CTD PMID:19774075 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064
JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions
increases expression
ISO 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA] CTD PMID:28962527 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression
multiple interactions
ISO Amiodarone results in increased expression of CIDEC mRNA; Amiodarone results in increased expression of CIDEC protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]
CTD PMID:28962527 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression EXP Amiodarone affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP Amiodarone affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression ISO Amiodarone results in increased expression of CLCN5 mRNA CTD PMID:19774075 NCBI chr  X:15,185,353...15,339,977
Ensembl chr  X:15,185,451...15,334,264
JBrowse link
G Clcn6 chloride voltage-gated channel 6 increases expression ISO Amiodarone results in increased expression of CLCN6 mRNA CTD PMID:19774075 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Amiodarone affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
JBrowse link
G Clptm1l CLPTM1-like affects expression EXP Amiodarone affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO Amiodarone results in increased expression of CLPX mRNA CTD PMID:24535564 NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
JBrowse link
G Clvs2 clavesin 2 increases expression ISO Amiodarone results in increased expression of CLVS2 mRNA CTD PMID:19774075 NCBI chr 1:23,735,272...23,762,997
Ensembl chr 1:23,735,272...23,842,692
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of CMBL mRNA
Amiodarone results in increased expression of CMBL mRNA
CTD PMID:19483382 PMID:24535564 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression EXP Amiodarone affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 affects expression EXP Amiodarone affects the expression of CMTM6 mRNA CTD PMID:18355885 NCBI chr 8:114,422,681...114,441,034
Ensembl chr 8:114,422,921...114,441,033
JBrowse link
G Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 increases expression ISO Amiodarone results in increased expression of CMTM7 mRNA CTD PMID:19774075 NCBI chr 8:114,448,037...114,474,958
Ensembl chr 8:114,448,042...114,474,621
JBrowse link
G Cmya5 cardiomyopathy associated 5 increases expression ISO Amiodarone results in increased expression of CMYA5 mRNA CTD PMID:19774075 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364
JBrowse link
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 increases expression ISO Amiodarone results in increased expression of CNIH3 mRNA CTD PMID:19774075 NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121
JBrowse link
G Cnnm2 cyclin and CBS domain divalent metal cation transport mediator 2 increases expression ISO Amiodarone results in increased expression of CNNM2 mRNA CTD PMID:19774075 NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 increases expression ISO Amiodarone results in increased expression of CNOT7 mRNA CTD PMID:19774075 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase increases expression ISO Amiodarone results in increased expression of CNP mRNA CTD PMID:19774075 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression ISO Amiodarone results in increased expression of COL11A1 mRNA CTD PMID:19774075 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
JBrowse link
G Col27a1 collagen type XXVII alpha 1 chain increases expression ISO Amiodarone results in increased expression of COL27A1 mRNA CTD PMID:19774075 NCBI chr 5:76,647,302...76,765,987
Ensembl chr 5:76,647,429...76,765,174
JBrowse link
G Col8a2 collagen type VIII alpha 2 chain increases expression ISO Amiodarone results in increased expression of COL8A2 mRNA CTD PMID:19774075 NCBI chr 5:138,586,201...138,613,627
Ensembl chr 5:138,585,999...138,612,850
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects expression EXP Amiodarone affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 4:120,366,540...120,392,502 JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression EXP Amiodarone affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
JBrowse link
G Copz2 COPI coat complex subunit zeta 2 increases expression ISO Amiodarone results in increased expression of COPZ2 mRNA CTD PMID:24535564 NCBI chr10:81,832,441...81,845,514
Ensembl chr10:81,832,418...81,845,514
JBrowse link
G Coq2 coenzyme Q2, polyprenyltransferase increases expression ISO Amiodarone results in increased expression of COQ2 mRNA CTD PMID:24489787 NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of COQ3 mRNA
Amiodarone results in increased expression of COQ3 mRNA
CTD PMID:19483382 PMID:24489787 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Coro2a coronin 2A increases expression ISO Amiodarone results in increased expression of CORO2A mRNA CTD PMID:19774075 NCBI chr 5:60,825,630...60,881,917
Ensembl chr 5:60,828,247...60,859,035
JBrowse link
G Cort cortistatin affects expression EXP Amiodarone affects the expression of CORT mRNA CTD PMID:31324950 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 increases expression ISO Amiodarone results in increased expression of COX15 mRNA CTD PMID:24489787 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 increases expression ISO Amiodarone results in increased expression of COX17 mRNA CTD PMID:24489787 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP Amiodarone affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cox6b2 cytochrome c oxidase subunit 6B2 increases expression ISO Amiodarone results in increased expression of COX6B2 mRNA CTD PMID:24535564 NCBI chr 1:69,094,009...69,095,312 JBrowse link
G Cplx2 complexin 2 increases expression ISO Amiodarone results in increased expression of CPLX2 mRNA CTD PMID:19774075 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression EXP Amiodarone affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
JBrowse link
G Cpped1 calcineurin-like phosphoesterase domain containing 1 affects expression EXP Amiodarone affects the expression of CPPED1 mRNA CTD PMID:18355885 NCBI chr10:3,701,522...3,821,050
Ensembl chr10:3,701,459...3,821,054
JBrowse link
G Cpq carboxypeptidase Q affects expression EXP Amiodarone affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
affects expression
ISO Amiodarone results in increased expression of CPT1A mRNA
Amiodarone affects the expression of CPT1A mRNA
CTD PMID:24489787 PMID:29248575 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression ISO Amiodarone results in increased expression of CPT2 mRNA CTD PMID:24489787 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crb3 crumbs cell polarity complex component 3 increases expression ISO Amiodarone results in increased expression of CRB3 mRNA CTD PMID:19774075 NCBI chr 9:1,898,531...1,903,860
Ensembl chr 9:1,896,623...1,903,859
JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Amiodarone affects the expression of CREM mRNA CTD PMID:18355885 PMID:19483382 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression ISO Amiodarone results in decreased expression of CROT mRNA CTD PMID:27089845 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Crp C-reactive protein multiple interactions ISO Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]; Amiodarone inhibits the reaction [CRP protein results in increased expression of TNF protein] CTD PMID:19225199 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 decreases expression EXP Amiodarone results in decreased expression of CRTC1 mRNA CTD PMID:17991464 NCBI chr16:18,988,197...19,046,913
Ensembl chr16:18,988,250...19,043,381
JBrowse link
G Csnk2b casein kinase 2 beta affects expression EXP Amiodarone affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression EXP Amiodarone affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression ISO Amiodarone results in increased expression of CSRP3 mRNA CTD PMID:24535564 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cst6 cystatin E/M increases expression ISO Amiodarone results in increased expression of CST6 mRNA CTD PMID:19774075 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
JBrowse link
G Cst7 cystatin F increases expression ISO Amiodarone results in increased expression of CST7 mRNA CTD PMID:19774075 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Ctc1 CST telomere replication complex component 1 increases expression ISO Amiodarone results in increased expression of CTC1 mRNA CTD PMID:19774075 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 increases expression ISO Amiodarone results in increased expression of CTLA4 mRNA CTD PMID:19774075 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Ctnna1 catenin alpha 1 affects expression EXP Amiodarone affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Amiodarone inhibits the reaction [Dexamethasone results in increased expression of CXCL2 mRNA] CTD PMID:25900201 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity
increases response to substance
multiple interactions
EXP
ISO
Amiodarone results in increased expression of CYP1A1 mRNA
Amiodarone results in decreased activity of CYP1A1 protein
CYP1A1 protein results in increased susceptibility to Amiodarone
Amiodarone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CTD PMID:19224547 PMID:20362646 PMID:26477383 PMID:34181028 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
multiple interactions
decreases response to substance
ISO Amiodarone results in decreased activity of CYP1A2 protein
[Amiodarone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin
CYP1A2 protein results in decreased susceptibility to Amiodarone
CTD PMID:16449812 PMID:26477383 PMID:26599973 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases response to substance ISO CYP1B1 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Amiodarone results in increased expression of CYP26A1 mRNA CTD PMID:19774075 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression EXP Amiodarone affects the expression of CYP2A1 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression ISO Amiodarone results in increased expression of CYP2B10 mRNA CTD PMID:24535564 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 affects expression EXP Amiodarone affects the expression of CYP2B15 mRNA CTD PMID:18355885 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression EXP Amiodarone affects the expression of CYP2B2 mRNA CTD PMID:19483382 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression
decreases response to substance
EXP
ISO
Amiodarone affects the expression of CYP2B3 mRNA
CYP2B6 protein results in decreased susceptibility to Amiodarone
CTD PMID:19483382 PMID:26477383 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 decreases response to substance ISO CYP2C18 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases response to substance ISO CYP2C19 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
decreases response to substance
multiple interactions
increases metabolic processing
ISO Amiodarone results in decreased activity of CYP2C8 protein
CYP2C8 protein results in decreased susceptibility to Amiodarone
torsemide inhibits the reaction [Amiodarone results in decreased activity of CYP2C8 protein]
CYP2C8 protein results in increased metabolism of Amiodarone
CTD PMID:15304522 PMID:15716363 PMID:26477383
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 affects expression EXP Amiodarone affects the expression of CYP2D3 mRNA CTD PMID:19483382 NCBI chr 7:113,917,711...113,922,068 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects expression
multiple interactions
increases expression
decreases activity
EXP
ISO
Amiodarone affects the expression of CYP2D4 mRNA
CYP2D6 gene polymorphism affects the reaction [Amiodarone results in increased abundance of Metoprolol]
Amiodarone results in increased expression of CYP2D6 mRNA
Amiodarone results in decreased activity of CYP2D6 protein
CTD PMID:15541258 PMID:16449812 PMID:19483382 PMID:19774075 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases response to substance ISO CYP2E1 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP Amiodarone affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of CYP2J2 mRNA
Amiodarone affects the expression of CYP2J4 mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 increases expression ISO Amiodarone results in increased expression of CYP2R1 mRNA CTD PMID:19774075 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 affects expression EXP Amiodarone affects the expression of CYP2T1 mRNA CTD PMID:19483382 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 decreases expression ISO Amiodarone results in decreased expression of CYP2U1 mRNA CTD PMID:24535564 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression ISO Amiodarone results in decreased expression of CYP39A1 mRNA CTD PMID:24535564 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
decreases activity
multiple interactions
increases metabolic processing
increases response to substance
decreases ethylation
EXP
ISO
Amiodarone results in increased expression of CYP3A4 mRNA
Amiodarone results in decreased activity of CYP3A4 protein
[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of CXCL8 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of TNF protein; [CYP3A4 protein results in increased metabolism of Amiodarone] which results in increased abundance of mono-N-desethylamiodarone; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Amiodarone]
CYP3A4 protein results in increased susceptibility to Amiodarone
CYP3A4 protein results in decreased ethylation of Amiodarone
CTD PMID:7905403 PMID:8445979 PMID:15304522 PMID:15869686 PMID:16449812 More... NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression EXP Amiodarone affects the expression of CYP3A23-3A1 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression
decreases response to substance
EXP
ISO
Amiodarone affects the expression of CYP3A9 mRNA
CYP3A5 protein results in decreased susceptibility to Amiodarone
CTD PMID:19483382 PMID:26477383 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Amiodarone results in increased expression of CYP4A1 mRNA CTD PMID:12883083 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Amiodarone affects the expression of CYP4A8 mRNA CTD PMID:19483382 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 affects expression EXP Amiodarone affects the expression of CYP4F2 mRNA CTD PMID:18355885 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 affects expression EXP Amiodarone affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP Amiodarone results in decreased expression of CYP7A1 mRNA CTD PMID:19224547 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Amiodarone results in decreased expression of CYP7B1 mRNA CTD PMID:24535564 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression ISO Amiodarone results in decreased expression of DACT1 mRNA CTD PMID:24535564 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
JBrowse link
G Dapk2 death-associated protein kinase 2 increases expression ISO Amiodarone results in increased expression of DAPK2 mRNA CTD PMID:19774075 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein affects expression EXP Amiodarone affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Dbn1 drebrin 1 increases expression ISO Amiodarone results in increased expression of DBN1 mRNA CTD PMID:19774075 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
G Dbndd1 dysbindin domain containing 1 increases expression ISO Amiodarone results in increased expression of DBNDD1 mRNA CTD PMID:19774075 NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression EXP Amiodarone affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression EXP Amiodarone affects the expression of DCAF8 mRNA CTD PMID:18355885 NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726
JBrowse link
G Dcst2 DC-STAMP domain containing 2 increases expression ISO Amiodarone results in increased expression of DCST2 mRNA CTD PMID:19774075 NCBI chr 2:174,781,806...174,795,834
Ensembl chr 2:174,781,902...174,795,832
JBrowse link
G Dctn1 dynactin subunit 1 increases expression ISO Amiodarone results in increased expression of DCTN1 mRNA CTD PMID:19774075 NCBI chr 4:115,671,024...115,703,824
Ensembl chr 4:115,661,638...115,703,815
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP Amiodarone affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddc dopa decarboxylase increases expression ISO Amiodarone results in increased expression of DDC mRNA CTD PMID:24489787 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
decreases response to substance
multiple interactions
ISO [Amiodarone results in increased expression of DDIT3 mRNA] which results in increased expression of TNFRSF10B mRNA; [Amiodarone results in increased expression of DDIT3 protein] which results in increased expression of TNFRSF10B protein; Amiodarone results in increased expression of DDIT3 mRNA; Amiodarone results in increased expression of DDIT3 protein
DDIT3 gene mutant form results in decreased susceptibility to Amiodarone
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; Amiodarone results in increased expression of and affects the localization of DDIT3 protein; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA]
DDIT3 mutant form inhibits the reaction [Amiodarone results in increased expression of TNFRSF10B]; Egtazic Acid inhibits the reaction [Amiodarone results in increased expression of DDIT3]
CTD PMID:19774075 PMID:21292685 PMID:28962527 PMID:32651653 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Amiodarone results in increased expression of DDIT4 mRNA CTD PMID:19774075 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO Amiodarone results in increased expression of DDX17 mRNA CTD PMID:19774075 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Ddx31 DEAD-box helicase 31 increases expression ISO Amiodarone results in increased expression of DDX31 mRNA CTD PMID:19774075 NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873
JBrowse link
G Ddx39a DExD-box helicase 39A increases expression ISO Amiodarone results in increased expression of DDX39A mRNA CTD PMID:19774075 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954
JBrowse link
G Ddx49 DEAD-box helicase 49 increases expression ISO Amiodarone results in increased expression of DDX49 mRNA CTD PMID:19774075 NCBI chr16:19,125,388...19,133,042
Ensembl chr16:19,125,384...19,133,616
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP Amiodarone affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dedd death effector domain-containing increases expression ISO Amiodarone results in increased expression of DEDD mRNA CTD PMID:19774075 NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332
JBrowse link
G Depp1 DEPP1, autophagy regulator increases expression ISO Amiodarone results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein increases expression ISO Amiodarone results in increased expression of DEPTOR mRNA CTD PMID:19774075 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Dexi Dexi homolog affects expression EXP Amiodarone affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of DGAT1 mRNA
Amiodarone results in increased expression of DGAT1 mRNA
CTD PMID:19483382 PMID:32651653 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO Amiodarone results in decreased expression of DGAT2 mRNA CTD PMID:28962527 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression EXP Amiodarone affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Amiodarone results in increased expression of DHRS2 mRNA CTD PMID:19774075 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression EXP Amiodarone affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression EXP Amiodarone affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression EXP Amiodarone affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
JBrowse link
G Dhx57 DExH-box helicase 57 increases expression ISO Amiodarone results in increased expression of DHX57 mRNA CTD PMID:19774075 NCBI chr 6:14,725,305...14,776,321
Ensembl chr 6:14,725,303...14,776,321
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity EXP
ISO
Amiodarone results in decreased activity of DIO1 protein CTD PMID:12538616 PMID:16131326 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression ISO Amiodarone results in increased expression of DLG4 mRNA CTD PMID:19774075 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 increases expression ISO Amiodarone results in increased expression of DLK2 mRNA CTD PMID:19774075 NCBI chr 9:14,677,102...14,681,515
Ensembl chr 9:14,676,562...14,681,594
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression EXP Amiodarone affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
JBrowse link
G Dnaaf3 dynein, axonemal, assembly factor 3 increases expression ISO Amiodarone results in increased expression of DNAAF3 mRNA CTD PMID:19774075 NCBI chr 1:69,291,300...69,299,365
Ensembl chr 1:69,291,454...69,299,344
JBrowse link
G Dnah7 dynein, axonemal, heavy chain 7 increases expression ISO Amiodarone results in increased expression of DNAH7 mRNA CTD PMID:19774075 NCBI chr 9:54,960,235...55,266,529
Ensembl chr 9:54,960,440...55,262,297
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 decreases expression ISO Amiodarone results in decreased expression of DNAJB11 mRNA CTD PMID:24535564 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 increases expression ISO Amiodarone results in increased expression of DNAJB12 mRNA CTD PMID:19774075 NCBI chr20:27,828,216...27,846,428
Ensembl chr20:27,828,235...27,846,427
JBrowse link
G Dnajb7 DnaJ heat shock protein family (Hsp40) member B7 increases expression ISO Amiodarone results in increased expression of DNAJB7 mRNA CTD PMID:19774075 NCBI chr 7:112,932,736...112,934,050
Ensembl chr 7:112,932,616...112,945,537
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression
multiple interactions
ISO Amiodarone results in increased expression of DNAJB9 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]
Amiodarone results in increased expression of DNAJB9 mRNA; Amiodarone results in increased expression of DNAJB9 protein
CTD PMID:19774075 PMID:28962527 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression
increases expression
multiple interactions
EXP
ISO
Amiodarone affects the expression of DNAJC3 mRNA
Amiodarone results in increased expression of DNAJC3 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJC3 mRNA]
CTD PMID:19483382 PMID:28962527 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dnase1 deoxyribonuclease 1 increases expression ISO Amiodarone results in increased expression of DNASE1 mRNA CTD PMID:19774075 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dock5 dedicator of cytokinesis 5 increases expression ISO Amiodarone results in increased expression of DOCK5 mRNA CTD PMID:19774075 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
JBrowse link
G Dpm2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory increases expression ISO Amiodarone results in increased expression of DPM2 mRNA CTD PMID:19774075 NCBI chr 3:15,855,952...15,858,867 JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP Amiodarone affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression EXP Amiodarone affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Drc7 dynein regulatory complex subunit 7 increases expression ISO Amiodarone results in increased expression of DRC7 mRNA CTD PMID:19774075 NCBI chr19:9,943,452...9,961,266
Ensembl chr19:9,943,456...9,961,163
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Amiodarone results in increased expression of DUSP1 mRNA CTD PMID:19774075 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Amiodarone results in increased expression of DUSP10 mRNA CTD PMID:19774075 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dut deoxyuridine triphosphatase increases expression ISO Amiodarone results in increased expression of DUT mRNA CTD PMID:19774075 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Eaf2 ELL associated factor 2 increases expression ISO Amiodarone results in increased expression of EAF2 mRNA CTD PMID:19774075 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression EXP Amiodarone affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression ISO Amiodarone results in increased expression of ECH1 mRNA CTD PMID:24535564 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects expression EXP Amiodarone affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Amiodarone affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Amiodarone affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
JBrowse link
G Ecpas Ecm29 proteasome adaptor and scaffold decreases expression EXP Amiodarone results in decreased expression of ECPAS mRNA CTD PMID:17991464 NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860
JBrowse link
G Eed embryonic ectoderm development increases expression ISO Amiodarone results in increased expression of EED mRNA CTD PMID:19774075 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP Amiodarone affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO Amiodarone results in increased expression of EEPD1 mRNA CTD PMID:19774075 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340
JBrowse link
G Efcab5 EF-hand calcium binding domain 5 increases expression ISO Amiodarone results in increased expression of EFCAB5 mRNA CTD PMID:19774075 NCBI chr10:61,926,031...62,041,708
Ensembl chr10:61,926,953...62,042,749
JBrowse link
G Efcc1 EF-hand and coiled-coil domain containing 1 increases expression ISO Amiodarone results in increased expression of EFCC1 mRNA CTD PMID:19774075 NCBI chr 4:120,188,202...120,223,464
Ensembl chr 4:120,188,470...120,217,516
JBrowse link
G Egfl6 EGF-like-domain, multiple 6 increases expression ISO Amiodarone results in increased expression of EGFL6 mRNA CTD PMID:19774075 NCBI chr  X:27,884,087...27,942,044
Ensembl chr  X:27,884,125...27,942,044
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Amiodarone results in decreased expression of EGFR mRNA CTD PMID:24535564 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 increases expression ISO Amiodarone results in increased expression of EGR1 mRNA CTD PMID:19774075 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression ISO Amiodarone results in increased expression of EGR2 mRNA CTD PMID:19774075 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression
decreases expression
increases expression
EXP
ISO
Amiodarone affects the expression of EHHADH mRNA
Amiodarone results in decreased expression of EHHADH mRNA
Amiodarone results in increased expression of EHHADH mRNA
CTD PMID:15265979 PMID:19483382 PMID:24489787 PMID:24535564 PMID:27089845 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 increases expression ISO Amiodarone results in increased expression of EHMT1 mRNA CTD PMID:19774075 NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO Amiodarone results in increased phosphorylation of EIF2A protein CTD PMID:21292685 PMID:28962527 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO Amiodarone results in increased expression of EIF2AK3 mRNA CTD PMID:19774075 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation ISO Amiodarone results in increased phosphorylation of EIF2S1 protein CTD PMID:32651653 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression EXP Amiodarone affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B affects expression EXP Amiodarone affects the expression of EIF4B mRNA CTD PMID:18355885 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
affects expression
ISO
EXP
Amiodarone inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]
Amiodarone results in decreased phosphorylation of EIF4EBP1 protein
Amiodarone affects the expression of EIF4EBP1 mRNA
CTD PMID:19483382 PMID:19771169 PMID:23912912 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression EXP Amiodarone affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression ISO Amiodarone results in increased expression of EIF5 mRNA CTD PMID:19774075
G Elmo3 engulfment and cell motility 3 increases expression ISO Amiodarone results in increased expression of ELMO3 mRNA CTD PMID:19774075 NCBI chr19:33,181,952...33,186,399
Ensembl chr19:33,182,036...33,186,410
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression ISO Amiodarone results in increased expression of ELOVL6 mRNA CTD PMID:24489787 PMID:29248575 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 increases expression ISO Amiodarone results in increased expression of ELP1 mRNA CTD PMID:19774075 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP Amiodarone affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Enho energy homeostasis associated decreases expression ISO Amiodarone results in decreased expression of ENHO mRNA CTD PMID:24535564 NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777
JBrowse link
G Eno1 enolase 1 affects expression EXP Amiodarone affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP Amiodarone affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression EXP Amiodarone affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 increases expression ISO Amiodarone results in increased expression of ENPP7 mRNA CTD PMID:19774075 NCBI chr10:104,242,223...104,246,589
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Epc1 enhancer of polycomb homolog 1 increases expression ISO Amiodarone results in increased expression of EPC1 mRNA CTD PMID:19774075 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425
JBrowse link
G Epc2 enhancer of polycomb homolog 2 increases expression ISO Amiodarone results in increased expression of EPC2 mRNA CTD PMID:19774075 NCBI chr 3:33,867,219...33,967,908
Ensembl chr 3:33,867,219...33,967,150
JBrowse link
G Epcam epithelial cell adhesion molecule affects expression EXP Amiodarone affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression EXP Amiodarone affects the expression of EPHX1 mRNA CTD PMID:18355885 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 increases expression ISO Amiodarone results in increased expression of ERI2 mRNA CTD PMID:19774075 NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665
JBrowse link
G Ermn ermin increases expression ISO Amiodarone results in increased expression of ERMN mRNA CTD PMID:19774075 NCBI chr 3:42,628,160...42,633,816
Ensembl chr 3:42,626,309...42,633,744
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation ISO Amiodarone results in increased phosphorylation of ERN1 protein CTD PMID:28962527 PMID:32651653 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta decreases expression ISO Amiodarone results in decreased expression of ERO1B mRNA CTD PMID:24535564 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Amiodarone affects the expression of ERP29 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Esd esterase D affects expression EXP Amiodarone affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects expression EXP Amiodarone affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase increases expression ISO Amiodarone results in increased expression of ETFDH mRNA CTD PMID:24489787 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745
JBrowse link
G Exo1 exonuclease 1 increases expression ISO Amiodarone results in increased expression of EXO1 mRNA CTD PMID:19774075 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G F11 coagulation factor XI decreases expression ISO Amiodarone results in decreased expression of F11 mRNA CTD PMID:24535564 NCBI chr16:46,986,107...47,009,015
Ensembl chr16:46,986,107...47,008,437
JBrowse link
G F2 coagulation factor II multiple interactions ISO Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein] CTD PMID:18974383 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases activity
ISO Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of and results in increased activity of F3 protein]
Amiodarone results in decreased activity of F3 protein
CTD PMID:18974383 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Faah fatty acid amide hydrolase affects expression EXP Amiodarone affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 5:129,479,774...129,499,018 JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression
decreases expression
ISO Amiodarone results in increased expression of FABP1 mRNA
Amiodarone results in decreased expression of FABP1 mRNA
CTD PMID:15342952 PMID:17567588 PMID:28962527 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression EXP Amiodarone results in increased expression of FADS1 mRNA CTD PMID:19224547 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions
affects expression
increases expression
ISO
EXP
[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of FADS2 mRNA]; FADS2 protein affects the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]
Amiodarone affects the expression of FADS2 mRNA
CTD PMID:19483382 PMID:21123845 PMID:29248575 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fam81a family with sequence similarity 81, member A increases expression ISO Amiodarone results in increased expression of FAM81A mRNA CTD PMID:19774075 NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875
JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Amiodarone results in increased expression of FAM89A mRNA CTD PMID:19774075 NCBI chr19:52,710,003...52,722,591
Ensembl chr19:52,710,019...52,722,631
JBrowse link
G Fanca FA complementation group A increases expression ISO Amiodarone results in increased expression of FANCA mRNA CTD PMID:19774075 NCBI chr19:51,304,021...51,362,586
Ensembl chr19:51,304,021...51,362,527
JBrowse link
G Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 increases expression ISO Amiodarone results in increased expression of FARP2 mRNA CTD PMID:19774075 NCBI chr 9:94,053,650...94,162,212
Ensembl chr 9:94,053,726...94,162,212
JBrowse link
G Fasn fatty acid synthase increases expression
affects expression
ISO Amiodarone results in increased expression of FASN mRNA
Amiodarone affects the expression of FASN mRNA
CTD PMID:24489787 PMID:29248575 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression EXP Amiodarone affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fbxo16 F-box protein 16 increases expression ISO Amiodarone results in increased expression of FBXO16 mRNA CTD PMID:19774075 NCBI chr15:39,492,268...39,541,493
Ensembl chr15:39,492,377...39,541,480
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Amiodarone results in increased expression of FBXO32 mRNA CTD PMID:19774075 NCBI chr 7:89,731,626...89,764,761
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb increases expression EXP Amiodarone results in increased expression of FCGR2B mRNA CTD PMID:25580480 NCBI chr13:83,191,253...83,207,776
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fcrl1 Fc receptor-like 1 increases expression ISO Amiodarone results in increased expression of FCRL1 mRNA CTD PMID:19774075 NCBI chr 2:172,809,451...172,829,780
Ensembl chr 2:172,790,934...172,829,753
JBrowse link
G Fcrl2 Fc receptor-like 2 increases expression ISO Amiodarone results in increased expression of FCRL2 mRNA CTD PMID:19774075 NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression EXP Amiodarone affects the expression of FDFT1 mRNA CTD PMID:19483382 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase affects expression EXP Amiodarone affects the expression of FDPS mRNA CTD PMID:19483382 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fdx2 ferredoxin 2 affects expression EXP Amiodarone affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849
JBrowse link
G Ffar3 free fatty acid receptor 3 increases expression ISO Amiodarone results in increased expression of FFAR3 mRNA CTD PMID:19774075 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 increases expression ISO Amiodarone results in increased expression of FGD4 mRNA CTD PMID:19774075 NCBI chr11:84,399,885...84,551,013
Ensembl chr11:84,399,816...84,546,972
JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 increases expression ISO Amiodarone results in increased expression of FGD5 mRNA CTD PMID:19774075 NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563
JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO Amiodarone results in increased expression of FGF21 mRNA CTD PMID:24489787 NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Fgfr1op2 FGFR1 oncogene partner 2 increases expression ISO Amiodarone results in increased expression of FGFR1OP2 mRNA CTD PMID:19774075 NCBI chr 4:179,491,602...179,512,630
Ensembl chr 4:179,491,599...179,512,630
JBrowse link
G Fibcd1 fibrinogen C domain containing 1 increases expression ISO Amiodarone results in increased expression of FIBCD1 mRNA CTD PMID:19774075 NCBI chr 3:15,092,681...15,126,399
Ensembl chr 3:15,092,681...15,126,399
JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO Amiodarone results in increased expression of FKBP10 mRNA CTD PMID:19774075 NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 decreases expression ISO Amiodarone results in decreased expression of FKBP11 mRNA CTD PMID:24535564 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
JBrowse link
G Flcn folliculin increases expression ISO Amiodarone results in increased expression of FLCN mRNA CTD PMID:19774075 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Amiodarone affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Amiodarone results in increased expression of FNDC4 mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 6:25,077,155...25,080,812 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO Amiodarone results in increased expression of FOS mRNA
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD PMID:17214612 PMID:19774075 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Amiodarone results in increased expression of FOSB mRNA CTD PMID:19774075 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO Amiodarone results in decreased expression of FOXA1 mRNA CTD PMID:27089845 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa3 forkhead box A3 decreases expression EXP
ISO
Amiodarone results in decreased expression of FOXA3 mRNA CTD PMID:17991464 PMID:24535564 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Amiodarone results in increased expression of FOXP3 mRNA CTD PMID:19774075 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression ISO Amiodarone results in increased expression of FRAS1 mRNA CTD PMID:19774075 NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726
JBrowse link
G Frmd3 FERM domain containing 3 increases expression ISO Amiodarone results in increased expression of FRMD3 mRNA CTD PMID:19774075 NCBI chr 5:87,764,604...88,032,261
Ensembl chr 5:87,764,604...88,031,091
JBrowse link
G Frmd5 FERM domain containing 5 increases expression ISO Amiodarone results in increased expression of FRMD5 mRNA CTD PMID:19774075 NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498
JBrowse link
G Fundc2 FUN14 domain containing 2 increases expression ISO Amiodarone results in increased expression of FUNDC2 mRNA CTD PMID:19774075 NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345
JBrowse link
G Fut4 fucosyltransferase 4 decreases expression EXP Amiodarone results in decreased expression of FUT4 mRNA CTD PMID:17991464 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
JBrowse link
G Fuz fuzzy planar cell polarity protein increases expression ISO Amiodarone results in increased expression of FUZ mRNA CTD PMID:19774075 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 increases expression ISO Amiodarone results in increased expression of FXYD1 mRNA CTD PMID:19774075 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression EXP
ISO
Amiodarone results in increased expression of G6PDX mRNA
Amiodarone results in increased expression of G6PD mRNA
CTD PMID:19224547 PMID:19774075 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Amiodarone results in increased expression of GADD45A mRNA CTD PMID:19774075 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Amiodarone results in increased expression of GADD45G mRNA CTD PMID:19774075 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression EXP Amiodarone results in increased expression of GAL mRNA CTD PMID:25580480 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Gal3st3 galactose-3-O-sulfotransferase 3 increases expression ISO Amiodarone results in increased expression of GAL3ST3 mRNA CTD PMID:19774075 NCBI chr 1:202,593,692...202,603,446
Ensembl chr 1:202,593,692...202,603,445
JBrowse link
G Galnt17 polypeptide N-acetylgalactosaminyltransferase 17 increases expression ISO Amiodarone results in increased expression of GALNT17 mRNA CTD PMID:19774075 NCBI chr12:25,323,839...25,780,036
Ensembl chr12:25,322,701...25,781,290
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression EXP Amiodarone affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Amiodarone affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gata2 GATA binding protein 2 decreases expression EXP Amiodarone results in decreased expression of GATA2 mRNA CTD PMID:17991464 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gatb glutamyl-tRNA amidotransferase subunit B increases expression ISO Amiodarone results in increased expression of GATB mRNA CTD PMID:24535564 NCBI chr 2:170,930,536...171,017,062
Ensembl chr 2:170,930,542...171,016,695
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression EXP Amiodarone affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Amiodarone results in increased expression of GBP2 mRNA CTD PMID:19774075 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression EXP Amiodarone affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
JBrowse link
G Gckr glucokinase regulator affects expression EXP Amiodarone affects the expression of GCKR mRNA CTD PMID:18355885 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Amiodarone results in increased expression of GDF15 mRNA CTD PMID:19774075 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdf5 growth differentiation factor 5 increases expression ISO Amiodarone results in increased expression of GDF5 mRNA CTD PMID:19774075 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Amiodarone results in increased expression of GDPD3 mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Amiodarone results in increased expression of GEM mRNA CTD PMID:19774075 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP Amiodarone results in increased expression of GFAP mRNA CTD PMID:22954530 PMID:25659768 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfod1 glucose-fructose oxidoreductase domain containing 1 increases expression ISO Amiodarone results in increased expression of GFOD1 mRNA CTD PMID:19774075 NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938
JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression EXP Amiodarone affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP Amiodarone inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA] CTD PMID:2910914 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Gins1 GINS complex subunit 1 increases expression ISO Amiodarone results in increased expression of GINS1 mRNA CTD PMID:19774075 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO Amiodarone results in decreased expression of GJA1 mRNA CTD PMID:15520326 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression ISO Amiodarone results in increased expression of GJA5 mRNA CTD PMID:19774075 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Amiodarone affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gjd3 gap junction protein, delta 3 increases expression ISO Amiodarone results in increased expression of GJD3 mRNA CTD PMID:19774075 NCBI chr10:83,933,694...83,935,759
Ensembl chr10:83,934,135...83,934,971
JBrowse link
G Gk5 glycerol kinase 5 increases expression ISO Amiodarone results in increased expression of GK5 mRNA CTD PMID:19774075 NCBI chr 8:96,682,469...96,751,407
Ensembl chr 8:96,682,470...96,749,166
JBrowse link
G Gkap1 G kinase anchoring protein 1 increases expression ISO Amiodarone results in increased expression of GKAP1 mRNA CTD PMID:19774075 NCBI chr17:6,383,963...6,423,684
Ensembl chr17:6,383,963...6,423,679
JBrowse link
G Gls2 glutaminase 2 affects expression EXP Amiodarone affects the expression of GLS2 mRNA CTD PMID:18355885 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression EXP Amiodarone results in increased expression of GLUD1 protein CTD PMID:16538043 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Gnas GNAS complex locus increases expression ISO Amiodarone results in increased expression of GNAS mRNA CTD PMID:19774075 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gnl1 G protein nucleolar 1 decreases expression EXP Amiodarone results in decreased expression of GNL1 mRNA CTD PMID:17991464 NCBI chr20:2,783,130...2,792,115
Ensembl chr20:2,778,985...2,792,115
JBrowse link
G Gon4l gon-4 like increases expression ISO Amiodarone results in increased expression of GON4L mRNA CTD PMID:19774075 NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 affects expression EXP Amiodarone affects the expression of GOT2 mRNA CTD PMID:18355885 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Amiodarone results in increased expression of GPAM mRNA CTD PMID:19224547 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Amiodarone results in increased expression of GPAT3 mRNA CTD PMID:24535564 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression EXP Amiodarone affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C increases expression ISO Amiodarone results in increased expression of GPRC5C mRNA CTD PMID:19774075 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
multiple interactions
increases activity
ISO Amiodarone results in increased expression of GPT protein
1-aminobenzotriazole promotes the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]; [Dexamethasone results in increased susceptibility to Amiodarone] which results in increased expression of GPT protein; Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]; gadolinium chloride inhibits the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]
Amiodarone results in increased activity of GPT protein
CTD PMID:8522712 PMID:24685772 PMID:25900201 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Amiodarone results in increased expression of GPT2 mRNA CTD PMID:24489787 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Amiodarone affects the expression of GPX1 mRNA CTD PMID:19483382 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression EXP Amiodarone affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Grb14 growth factor receptor bound protein 14 affects expression EXP Amiodarone affects the expression of GRB14 mRNA CTD PMID:18355885 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Amiodarone affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 7:107,962,194...107,965,368
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases expression ISO Amiodarone results in increased expression of GRM2 mRNA CTD PMID:19774075 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression EXP Amiodarone affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
JBrowse link
G Gsn gelsolin increases expression EXP Amiodarone results in increased expression of GSN mRNA CTD PMID:17991464 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsto2 glutathione S-transferase omega 2 increases expression ISO Amiodarone results in increased expression of GSTO2 mRNA CTD PMID:19774075 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Amiodarone affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 increases expression ISO Amiodarone results in increased expression of GSTZ1 mRNA CTD PMID:19774075 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 affects expression EXP Amiodarone affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 increases expression ISO Amiodarone results in increased expression of GUCY1A2 mRNA CTD PMID:19774075 NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO Amiodarone results in increased expression of GUCY1B1 mRNA CTD PMID:19774075 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Gzma granzyme A affects expression EXP Amiodarone affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G H2aj H2A.J histone increases expression ISO Amiodarone results in increased expression of H2AJ mRNA CTD PMID:19774075 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006
JBrowse link
G H3f3b H3.3 histone B affects expression EXP Amiodarone affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Amiodarone affects the expression of HAL mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression EXP Amiodarone affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression EXP Amiodarone affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr10:15,323,830...15,324,677 JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Amiodarone affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 increases expression ISO Amiodarone results in increased expression of HCN1 mRNA CTD PMID:19774075 NCBI chr 2:49,495,771...49,899,702
Ensembl chr 2:49,495,771...49,899,774
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 decreases expression EXP Amiodarone results in decreased expression of HCN2 mRNA CTD PMID:17711693 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 decreases expression EXP Amiodarone results in decreased expression of HCN4 mRNA CTD PMID:17711693 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639
JBrowse link
G Hdc histidine decarboxylase affects expression EXP Amiodarone affects the expression of HDC mRNA CTD PMID:19483382 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hdx highly divergent homeobox increases expression ISO Amiodarone results in increased expression of HDX mRNA CTD PMID:19774075 NCBI chr  X:76,552,539...76,869,972
Ensembl chr  X:76,560,665...76,869,972
JBrowse link
G Helb DNA helicase B increases expression ISO Amiodarone results in increased expression of HELB mRNA CTD PMID:19774075 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Amiodarone results in increased expression of HERPUD1 mRNA CTD PMID:19774075 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression EXP Amiodarone results in decreased expression of HES6 mRNA CTD PMID:17991464 NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression ISO Amiodarone results in increased expression of HEXIM1 mRNA CTD PMID:19774075 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression EXP Amiodarone affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
JBrowse link
G Hgfac HGF activator increases expression ISO Amiodarone results in increased expression of HGFAC mRNA CTD PMID:19774075 NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278
JBrowse link
G Hira histone cell cycle regulator increases expression ISO Amiodarone results in increased expression of HIRA mRNA CTD PMID:19774075 NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529
JBrowse link
G Hist1h3b histone cluster 1, H3b increases expression ISO Amiodarone results in increased expression of H3C12 mRNA CTD PMID:19774075 NCBI chr17:42,722,805...42,723,925 JBrowse link
G Hjv hemojuvelin BMP co-receptor increases expression ISO Amiodarone results in increased expression of HJV mRNA CTD PMID:24535564 NCBI chr 2:184,065,970...184,069,851
Ensembl chr 2:184,065,970...184,069,850
JBrowse link
G Hmgb2 high mobility group box 2 affects expression EXP Amiodarone affects the expression of HMGB2 mRNA CTD PMID:18355885 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Amiodarone results in increased expression of HMGCR mRNA CTD PMID:24489787 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 affects expression EXP Amiodarone affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
JBrowse link
G Hmgxb4 HMG-box containing 4 increases expression ISO Amiodarone results in increased expression of HMGXB4 mRNA CTD PMID:19774075 NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of HMOX1 mRNA
Amiodarone affects the expression of HMOX1 mRNA
CTD PMID:18020914 PMID:19224547 PMID:19774075 PMID:25659768 PMID:31324950 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO Amiodarone results in increased expression of HNF4A mRNA CTD PMID:24489787 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnf4g hepatocyte nuclear factor 4, gamma increases expression ISO Amiodarone results in increased expression of HNF4G mRNA CTD PMID:19774075 NCBI chr 2:97,885,773...98,036,954
Ensembl chr 2:97,887,432...98,036,592
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO Amiodarone results in increased expression of HNRNPA1 mRNA CTD PMID:21163907 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hoxb6 homeo box B6 increases expression ISO Amiodarone results in increased expression of HOXB6 mRNA CTD PMID:19774075 NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449
JBrowse link
G Hoxc4 homeo box C4 increases expression ISO Amiodarone results in increased expression of HOXC4 mRNA CTD PMID:19774075 NCBI chr 7:134,135,279...134,173,133
Ensembl chr 7:134,170,591...134,173,133
JBrowse link
G Hpn hepsin increases expression ISO Amiodarone results in increased expression of HPN mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression EXP Amiodarone affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression EXP Amiodarone affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression ISO Amiodarone results in increased expression of HRK mRNA CTD PMID:19774075 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone increases expression ISO Amiodarone results in increased expression of HSCB mRNA CTD PMID:24535564 NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO Amiodarone results in increased expression of HSD17B11 mRNA CTD PMID:24535564 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Amiodarone affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression EXP Amiodarone affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Amiodarone results in increased expression of HSPD1 protein CTD PMID:16538043 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Amiodarone results in increased expression of HTATIP2 mRNA CTD PMID:24535564 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression EXP Amiodarone affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Htra2 HtrA serine peptidase 2 increases expression ISO Amiodarone results in increased expression of HTRA2 mRNA CTD PMID:24489787 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO Amiodarone results in increased expression of HUS1 mRNA CTD PMID:19774075 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions
ISO Amiodarone results in increased expression of ICAM1 mRNA
[Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein
CTD PMID:19774075 PMID:22785256 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Amiodarone results in increased expression of ID2 mRNA CTD PMID:23397585 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases expression ISO Amiodarone results in increased expression of IDH2 mRNA CTD PMID:24489787 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP Amiodarone affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of IGFALS mRNA
Amiodarone affects the expression of IGFALS mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Amiodarone results in increased expression of IGFBP1 mRNA CTD PMID:27089845 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Amiodarone affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Igsf8 immunoglobulin superfamily, member 8 increases expression ISO Amiodarone results in increased expression of IGSF8 mRNA CTD PMID:19774075 NCBI chr13:84,770,348...84,781,534
Ensembl chr13:84,770,279...84,778,576
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO Amiodarone results in increased expression of IL10RA mRNA CTD PMID:19774075 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Il18 interleukin 18 multiple interactions ISO Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA] CTD PMID:25900201 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO Amiodarone results in increased expression of IL1A mRNA
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone
CTD PMID:19362101 PMID:19774075 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
[Amiodarone co-treated with Dexamethasone] results in decreased expression of IL1B mRNA
Amiodarone results in increased expression of IL1B mRNA
CTD PMID:25580480 PMID:25900201 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il33 interleukin 33 affects expression EXP Amiodarone affects the expression of IL33 mRNA CTD PMID:18355885 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
increases secretion
ISO Amiodarone results in increased expression of IL6 mRNA
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone; Prednisolone inhibits the reaction [Amiodarone results in increased secretion of IL6 protein]
CTD PMID:11288978 PMID:19362101 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Impa1 inositol monophosphatase 1 affects expression EXP Amiodarone affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Inhba inhibin subunit beta A decreases expression ISO Amiodarone results in decreased expression of INHBA mRNA CTD PMID:24535564 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inhbe inhibin subunit beta E affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of INHBE mRNA
Amiodarone results in increased expression of INHBE mRNA
CTD PMID:15342952 PMID:17175557 PMID:17567588 PMID:19483382 PMID:19774075 NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Amiodarone results in increased expression of INKA2 mRNA CTD PMID:19774075 NCBI chr 2:193,185,275...193,200,643
Ensembl chr 2:193,185,275...193,200,642
JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein] CTD PMID:28962527 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase increases expression ISO Amiodarone results in increased expression of IPPK mRNA CTD PMID:19774075 NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO Amiodarone results in increased expression of IRAK2 mRNA CTD PMID:19774075 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO Amiodarone results in increased expression of IRF1 mRNA CTD PMID:19774075 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Isx intestine-specific homeobox increases expression ISO Amiodarone results in increased expression of ISX mRNA CTD PMID:19774075 NCBI chr19:13,218,552...13,239,754
Ensembl chr19:13,218,552...13,239,760
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 affects expression EXP Amiodarone affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO Amiodarone results in decreased expression of ITGB5 mRNA CTD PMID:23397585 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 increases expression ISO Amiodarone results in increased expression of ITIH2 mRNA CTD PMID:19774075 NCBI chr17:68,375,518...68,411,849
Ensembl chr17:68,375,567...68,411,841
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression EXP Amiodarone affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Ivns1abp influenza virus NS1A binding protein increases expression EXP Amiodarone results in increased expression of IVNS1ABP mRNA CTD PMID:17991464 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Jak1 Janus kinase 1 affects expression EXP Amiodarone affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 increases expression ISO Amiodarone results in increased expression of JAKMIP3 mRNA CTD PMID:19774075 NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:193,811,513...193,881,104
JBrowse link
G Jrkl JRK-like increases expression ISO Amiodarone results in increased expression of JRKL mRNA CTD PMID:19774075 NCBI chr 8:10,224,172...10,227,068
Ensembl chr 8:10,224,172...10,227,068
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
EXP
ISO
Amiodarone results in increased expression of JUN mRNA; Amiodarone results in increased expression of JUN protein
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD PMID:11597910 PMID:17214612 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 increases expression ISO Amiodarone results in increased expression of KCNA4 mRNA CTD PMID:15520326 NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases expression ISO
EXP
Amiodarone results in decreased expression of KCNA5 mRNA CTD PMID:8973384 PMID:9302343 PMID:15520326 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 increases expression ISO Amiodarone results in increased expression of KCNAB1 mRNA CTD PMID:15520326 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Amiodarone results in decreased expression of KCNB1 mRNA CTD PMID:15520326 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Amiodarone results in decreased expression of KCND2 mRNA CTD PMID:15520326 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 increases expression ISO Amiodarone results in increased expression of KCNE3 mRNA CTD PMID:15520326 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 increases expression ISO Amiodarone results in increased expression of KCNE5 mRNA CTD PMID:19774075 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects activity
decreases activity
multiple interactions
ISO Amiodarone affects the activity of KCNH2 protein
Amiodarone results in decreased activity of KCNH2 protein
Amiodarone binds to and results in decreased activity of KCNH2 protein; Amiodarone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]; Amiodarone promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [Amiodarone results in decreased activity of KCNH2 protein]; Potassium inhibits the reaction [Amiodarone results in decreased activity of KCNH2 protein]
CTD PMID:10208308 PMID:11238279 PMID:15272206 PMID:15618689 PMID:15671647 More... NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 increases expression ISO Amiodarone results in increased expression of KCNJ2 mRNA CTD PMID:19774075 NCBI chr10:96,060,849...96,071,401
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 increases expression ISO Amiodarone results in increased expression of KCNK1 mRNA CTD PMID:15520326 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
JBrowse link
G Kcnk12 potassium two pore domain channel subfamily K member 12 increases expression ISO Amiodarone results in increased expression of KCNK12 mRNA CTD PMID:19774075 NCBI chr 6:6,740,147...6,790,664
Ensembl chr 6:6,739,991...6,790,661
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 increases expression ISO Amiodarone results in increased expression of KCNMA1 mRNA CTD PMID:19774075 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kctd14 potassium channel tetramerization domain containing 14 increases expression ISO Amiodarone results in increased expression of KCTD14 mRNA CTD PMID:19774075 NCBI chr 1:151,761,045...151,766,693
Ensembl chr 1:151,761,663...151,766,691
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression EXP Amiodarone affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
JBrowse link
G Kdr kinase insert domain receptor affects expression EXP Amiodarone affects the expression of KDR mRNA CTD PMID:19483382 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression EXP Amiodarone results in decreased expression of KEAP1 mRNA CTD PMID:17991464 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 increases expression ISO Amiodarone results in increased expression of KHDRBS3 mRNA CTD PMID:24535564 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
JBrowse link
G Kif16b kinesin family member 16B increases expression ISO Amiodarone results in increased expression of KIF16B mRNA CTD PMID:19774075 NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019
JBrowse link
G Kif17 kinesin family member 17 increases expression ISO Amiodarone results in increased expression of KIF17 mRNA CTD PMID:19774075 NCBI chr 5:150,482,288...150,521,471
Ensembl chr 5:150,481,578...150,519,638
JBrowse link
G Kifc1 kinesin family member C1 increases expression ISO Amiodarone results in increased expression of KIFC1 mRNA CTD PMID:19774075 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Kitlg KIT ligand increases expression ISO Amiodarone results in increased expression of KITLG mRNA CTD PMID:19774075 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klf10 Kruppel-like factor 10 increases expression ISO Amiodarone results in increased expression of KLF10 mRNA CTD PMID:19774075 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klf15 Kruppel-like factor 15 increases expression ISO Amiodarone results in increased expression of KLF15 mRNA CTD PMID:19774075 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
JBrowse link
G Klf16 Kruppel-like factor 16 increases expression ISO Amiodarone results in increased expression of KLF16 mRNA CTD PMID:19774075 NCBI chr 7:9,138,503...9,148,322
Ensembl chr 7:9,138,503...9,148,317
JBrowse link
G Klf4 Kruppel like factor 4 increases expression ISO Amiodarone results in increased expression of KLF4 mRNA CTD PMID:19774075 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klhl28 kelch-like family member 28 increases expression ISO Amiodarone results in increased expression of KLHL28 mRNA CTD PMID:19774075 NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164
JBrowse link
G Klk14 kallikrein related-peptidase 14 increases expression ISO Amiodarone results in increased expression of KLK14 mRNA CTD PMID:19774075 NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240
JBrowse link
G Krt17 keratin 17 increases expression ISO Amiodarone results in increased expression of KRT17 mRNA CTD PMID:19774075 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt23 keratin 23 increases expression ISO Amiodarone results in increased expression of KRT23 mRNA CTD PMID:24535564 NCBI chr10:84,434,675...84,450,722
Ensembl chr10:84,434,380...84,450,983
JBrowse link
G Krt8 keratin 8 affects expression EXP Amiodarone affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 increases expression ISO Amiodarone results in increased expression of L3MBTL1 mRNA CTD PMID:19774075 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
JBrowse link
G Lama2 laminin subunit alpha 2 increases expression ISO Amiodarone results in increased expression of LAMA2 mRNA CTD PMID:24489787 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530
JBrowse link
G Lars2 leucyl-tRNA synthetase 2, mitochondrial increases expression ISO Amiodarone results in increased expression of LARS2 mRNA CTD PMID:24489787 NCBI chr 8:123,010,271...123,108,957
Ensembl chr 8:123,010,293...123,106,395
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression EXP Amiodarone affects the expression of LCAT mRNA CTD PMID:19483382 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression EXP Amiodarone affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
JBrowse link
G Lctl lactase-like increases expression ISO Amiodarone results in increased expression of LCTL mRNA CTD PMID:19774075 NCBI chr 8:64,618,356...64,654,851
Ensembl chr 8:64,618,350...64,639,357
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
decreases expression
ISO
EXP
Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA]
Amiodarone results in decreased expression of LDLR mRNA; Amiodarone results in decreased expression of LDLR protein
Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein]
CTD PMID:8137927 PMID:9071962 PMID:9712728 PMID:9751232 PMID:12538616 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lelp1 late cornified envelope-like proline-rich 1 increases expression ISO Amiodarone results in increased expression of LELP1 mRNA CTD PMID:19774075
G Lhcgr luteinizing hormone/choriogonadotropin receptor increases expression ISO Amiodarone results in increased expression of LHCGR mRNA CTD PMID:19774075 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Amiodarone results in increased expression of LIF mRNA CTD PMID:19774075 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component increases expression ISO Amiodarone results in increased expression of LIN7A mRNA CTD PMID:19774075 NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550
JBrowse link
G Lipc lipase C, hepatic type affects expression EXP Amiodarone affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipe lipase E, hormone sensitive type multiple interactions
increases phosphorylation
ISO INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein] CTD PMID:28962527 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G LOC100909569 zinc finger protein 91-like increases expression ISO Amiodarone results in increased expression of ZNF624 mRNA CTD PMID:19774075 NCBI chr 7:7,853,363...7,891,014
Ensembl chr 7:7,853,403...7,890,974
JBrowse link
G LOC103689958 olfactory receptor 49-like increases expression ISO Amiodarone results in increased expression of OR6T1 mRNA CTD PMID:19774075 NCBI chr 1:65,911,907...65,913,255
Ensembl chr 1:65,912,105...65,913,079
JBrowse link
G LOC499240 similar to predicted gene ICRFP703B1614Q5.5 increases expression ISO Amiodarone results in increased expression of C11ORF16 mRNA CTD PMID:19774075 NCBI chr 1:163,742,987...163,754,926
Ensembl chr 1:163,743,021...163,754,089
JBrowse link
G LOC500124 similar to RIKEN cDNA 4921507P07 increases expression ISO Amiodarone results in increased expression of C7ORF31 mRNA CTD PMID:19774075 NCBI chr 4:79,663,375...79,688,282
Ensembl chr 4:79,663,376...79,689,072
JBrowse link
G LOC684819 similar to H3 histone, family 2 isoform 2 increases expression ISO Amiodarone results in increased expression of H3C11 mRNA CTD PMID:19774075
G LOC688459 hypothetical protein LOC688459 increases expression ISO Amiodarone results in increased expression of C6ORF141 mRNA CTD PMID:19774075 NCBI chr 9:20,024,916...20,029,094
Ensembl chr 9:20,024,916...20,029,094
JBrowse link
G Lox lysyl oxidase affects expression EXP Amiodarone affects the expression of LOX mRNA CTD PMID:18355885 PMID:19483382 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 increases expression ISO Amiodarone results in increased expression of LPCAT3 mRNA CTD PMID:24489787 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
G Lpin3 lipin 3 increases expression ISO Amiodarone results in increased expression of LPIN3 mRNA CTD PMID:24489787 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP Amiodarone affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
JBrowse link
G Lrp5 LDL receptor related protein 5 increases expression ISO Amiodarone results in increased expression of LRP5 mRNA CTD PMID:19774075 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lss lanosterol synthase increases expression
affects expression
EXP
ISO
Amiodarone results in increased expression of LSS mRNA
Amiodarone affects the expression of LSS mRNA
CTD PMID:15342952 PMID:17567588 PMID:19224547 PMID:24489787 PMID:29248575 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO Amiodarone results in increased expression of LY6D mRNA CTD PMID:24489787 NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733
JBrowse link
G Lyz2 lysozyme 2 increases expression ISO Amiodarone results in increased expression of LYZ mRNA CTD PMID:19774075 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 increases expression ISO Amiodarone results in increased expression of MACROD2 mRNA CTD PMID:19774075 NCBI chr 3:127,720,066...129,737,511 JBrowse link
G Macroh2a1 macroH2A.1 histone affects expression EXP Amiodarone affects the expression of MACROH2A1 mRNA CTD PMID:18355885 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Amiodarone results in increased expression of MAFG mRNA CTD PMID:19774075 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 affects expression EXP Amiodarone affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
JBrowse link
G Manba mannosidase beta affects expression EXP Amiodarone affects the expression of MANBA mRNA CTD PMID:18355885 NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation ISO Amiodarone results in increased lipidation of MAP1LC3B protein CTD PMID:32651653 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Amiodarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Masp1 MBL associated serine protease 1 increases expression ISO Amiodarone results in increased expression of MASP1 mRNA CTD PMID:19774075 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
G Masp2 MBL associated serine protease 2 affects expression EXP Amiodarone affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
JBrowse link
G Mbp myelin basic protein affects expression EXP Amiodarone affects the expression of MBP mRNA CTD PMID:25659768 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Amiodarone results in increased expression of MCAM mRNA CTD PMID:19774075 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
JBrowse link
G Mcf2 MCF.2 cell line derived transforming sequence increases expression ISO Amiodarone results in increased expression of MCF2 mRNA CTD PMID:19774075 NCBI chr  X:138,414,077...138,514,828
Ensembl chr  X:138,409,256...138,514,446
JBrowse link
G Me1 malic enzyme 1 increases expression
affects expression
EXP Amiodarone results in increased expression of ME1 protein
Amiodarone affects the expression of ME1 mRNA
CTD PMID:16538043 PMID:19483382 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Med11 mediator complex subunit 11 increases expression ISO Amiodarone results in increased expression of MED11 mRNA CTD PMID:19774075 NCBI chr10:55,164,304...55,166,134
Ensembl chr10:55,164,326...55,166,533
JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression ISO Amiodarone results in increased expression of MEF2C mRNA CTD PMID:19774075 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 increases expression
decreases expression
ISO Amiodarone results in increased expression of MFHAS1 mRNA
Amiodarone results in decreased expression of MFHAS1 mRNA
CTD PMID:19774075 PMID:24535564 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743
JBrowse link
G Mfn2 mitofusin 2 increases expression ISO Amiodarone results in increased expression of MFN2 mRNA CTD PMID:24489787 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mfsd1 major facilitator superfamily domain containing 1 decreases expression EXP Amiodarone results in decreased expression of MFSD1 mRNA CTD PMID:17991464 NCBI chr 2:151,846,130...151,866,168
Ensembl chr 2:151,846,146...151,867,045
JBrowse link
G Mgat4a alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A increases expression ISO Amiodarone results in increased expression of MGAT4A mRNA CTD PMID:19774075 NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Amiodarone results in increased expression of MGST1 mRNA CTD PMID:19774075 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO Amiodarone results in increased expression of MGST3 mRNA CTD PMID:24535564 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Micall2 MICAL-like 2 increases expression ISO Amiodarone results in increased expression of MICALL2 mRNA CTD PMID:19774075 NCBI chr12:14,899,151...14,927,949
Ensembl chr12:14,899,157...14,927,946
JBrowse link
G Mid2 midline 2 increases expression ISO Amiodarone results in increased expression of MID2 mRNA CTD PMID:19774075 NCBI chr  X:104,354,692...104,456,757
Ensembl chr  X:104,355,316...104,453,473
JBrowse link
G Mipep mitochondrial intermediate peptidase increases expression ISO Amiodarone results in increased expression of MIPEP mRNA CTD PMID:24489787 NCBI chr15:34,926,198...35,051,722
Ensembl chr15:34,926,207...35,051,727
JBrowse link
G Mir16 microRNA 16 decreases expression EXP Amiodarone results in decreased expression of MIR16 mRNA CTD PMID:17991464 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir224 microRNA 224 d