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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:organofluorine pesticide
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Accession:CHEBI:38805 term browser browse the term
Synonyms:related_synonym: fluoroorganic pesticide;   fluororganische Pestizide;   organofluorine pesticides


show annotations for term's descendants           Sort by:
etoxazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 affects phosphorylation
multiple interactions		 EXP etoxazole affects the phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; pyrazolanthrone affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; SB 203580 affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]; U 0126 affects the reaction [etoxazole affects the phosphorylation of AKT1 protein]		 CTD PMID:31744678
G ATF6 activating transcription factor 6 increases cleavage EXP etoxazole results in increased cleavage of ATF6 protein CTD PMID:31744678 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 increases expression EXP etoxazole results in increased expression of BAK1 protein CTD PMID:31744678 NCBI chr 7:29,808,849...29,815,345 JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP etoxazole results in increased expression of BAX protein CTD PMID:31744678 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G CCND1 cyclin D1 decreases expression EXP etoxazole results in decreased expression of CCND1 mRNA CTD PMID:31744678 NCBI chr 2:3,621,242...3,633,380
Ensembl chr 2:3,621,246...3,633,296 		JBrowse link
G CCNE1 cyclin E1 decreases expression EXP etoxazole results in decreased expression of CCNE1 mRNA CTD PMID:31744678 NCBI chr 6:39,919,541...39,933,224
Ensembl chr 6:39,919,624...39,933,363 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 increases expression EXP etoxazole results in increased expression of CXCL12 mRNA CTD PMID:31744678 NCBI chr14:91,516,383...91,543,857
Ensembl chr14:91,516,431...91,552,752 		JBrowse link
G CYCS cytochrome c, somatic increases expression EXP etoxazole results in increased expression of CYCS protein CTD PMID:31744678 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation EXP etoxazole results in increased phosphorylation of EIF2AK3 protein CTD PMID:31744678 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP etoxazole results in increased phosphorylation of EIF2S1 protein CTD PMID:31744678 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP etoxazole results in increased expression of HSPA5 protein CTD PMID:31744678 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G LEPR leptin receptor decreases expression EXP etoxazole results in decreased expression of LEPR mRNA CTD PMID:31744678 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions		 EXP etoxazole results in increased phosphorylation of MAPK1 protein
[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein; [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK1 protein; SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK1 protein]		 CTD PMID:31744678 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation		 EXP [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein] CTD PMID:31744678 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 EXP 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole results in increased phosphorylation of MAPK8 protein]; [SB 203580 co-treated with etoxazole] results in increased phosphorylation of MAPK8 protein; pyrazolanthrone inhibits the reaction [etoxazole results in increased phosphorylation of MAPK8 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK8 protein] CTD PMID:31744678 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G RPS6 ribosomal protein S6 affects phosphorylation
multiple interactions		 EXP etoxazole affects the phosphorylation of RPS6 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of RPS6 protein]; pyrazolanthrone affects the reaction [etoxazole affects the phosphorylation of RPS6 protein]; SB 203580 affects the reaction [etoxazole affects the phosphorylation of RPS6 protein]; U 0126 affects the reaction [etoxazole affects the phosphorylation of RPS6 protein]		 CTD PMID:31744678 NCBI chr 1:203,444,360...203,447,643
Ensembl chr 1:203,444,450...203,451,468 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 affects phosphorylation
multiple interactions		 EXP etoxazole affects the phosphorylation of RPS6KB1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein]; pyrazolanthrone affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein]; SB 203580 affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein]; U 0126 affects the reaction [etoxazole affects the phosphorylation of RPS6KB1 protein]		 CTD PMID:31744678 NCBI chr12:36,111,584...36,159,287
Ensembl chr12:36,111,653...36,160,376 		JBrowse link
G RXRB retinoid X receptor beta decreases expression EXP etoxazole results in decreased expression of RXRB mRNA CTD PMID:31744678 NCBI chr 7:25,236,005...25,242,842
Ensembl chr 7:25,236,007...25,242,875 		JBrowse link
G TNF tumor necrosis factor increases expression EXP etoxazole results in increased expression of TNF mRNA CTD PMID:31744678 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5066
    role 5030
      application 869
        pesticide 184
          organofluorine pesticide 19
            N-\{2-[(4,6-dimethoxypyrimidin-2-yl)(hydroxy)methyl]-6-(methoxymethyl)phenyl\}-1,1-difluoromethanesulfonamide + 0
            fluazaindolizine 0
            flucofuron 0
            fluensulfone 0
            fluoroimide 0
            inpyrfluxam 0
            isoflucypram 0
            organofluorine acaricide + 19
            organofluorine insecticide + 0
            pyraziflumid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5066
    subatomic particle 5057
      composite particle 5057
        hadron 5057
          baryon 5057
            nucleon 5057
              atomic nucleus 5057
                atom 5057
                  main group element atom 5026
                    p-block element atom 5023
                      carbon group element atom 4940
                        carbon atom 4939
                          organic molecular entity 4939
                            heteroorganic entity 4779
                              organohalogen compound 305
                                organofluorine compound 72
                                  organofluorine pesticide 19
                                    N-\{2-[(4,6-dimethoxypyrimidin-2-yl)(hydroxy)methyl]-6-(methoxymethyl)phenyl\}-1,1-difluoromethanesulfonamide + 0
                                    fluazaindolizine 0
                                    flucofuron 0
                                    fluensulfone 0
                                    fluoroimide 0
                                    inpyrfluxam 0
                                    isoflucypram 0
                                    organofluorine acaricide + 19
                                    organofluorine insecticide + 0
                                    pyraziflumid 0
paths to the root