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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dihydropterin
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Accession:CHEBI:38797 term browser browse the term
Synonyms:related_synonym: dihydropterins


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L-erythro-7,8-dihydrobiopterin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein increases abundance
multiple interactions
ISO APP gene mutant form results in increased abundance of 7,8-dihydrobiopterin
GW 501516 inhibits the reaction [APP gene mutant form results in increased abundance of 7,8-dihydrobiopterin]
CTD PMID:22886847 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein inhibits the reaction [[GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin]; EPO protein inhibits the reaction [HPH1 gene mutant form results in increased abundance of 7,8-dihydrobiopterin] CTD PMID:25041251 PMID:25490417 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Gch1 GTP cyclohydrolase 1 increases abundance
multiple interactions
ISO GCH1 gene mutant form results in increased abundance of 7,8-dihydrobiopterin
[GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin; EPO protein inhibits the reaction [[GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin]
CTD PMID:25490417 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO 7,8-dihydrobiopterin promotes the reaction [NOS3 protein results in increased abundance of Superoxides] CTD PMID:19011239 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    chemical entity 19841
      atom 19839
        nonmetal atom 19720
          nitrogen atom 18613
            nitrogen molecular entity 18613
              organonitrogen compound 18386
                organonitrogen heterocyclic compound 17559
                  pteridines 10209
                    pterins 9372
                      dihydropterin 4
                        (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate 0
                        (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin 0
                        2-amino-4-oxo-6-(erythro-1,2,3-trihydroxypropyl)-7,8-dihydroxypteridine triphosphate 0
                        2-amino-6-(1-hydroxyethyl)-7-methyl-7,8-dihydropteridin-4-one 0
                        2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol 0
                        2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-one + 0
                        2-amino-6-hydroxymethyl-7,7-dimethyl-7,8-dihydropteridin-4-one 0
                        6,7-dihydrobiopterin + 0
                        6-(1,2-dihydroxy-1-methyl-3-triphosphooxypropyl)-7-methyl-7,8-dihydropterin 0
                        6-pyruvoyl-7,8-dihydropterin 0
                        7,8-dihydro-D-neopterin 2',3'-cyclic phosphate 0
                        7,8-dihydrobiopterin + 4
                        7,8-dihydromonapterin 0
                        7,8-dihydromonapterin 3-triphosphate 0
                        7,8-dihydroneopterin + 0
                        7,8-dihydroneopterin 2'-phosphate 0
                        7,8-dihydroneopterin 3'-phosphate 0
                        7,8-dihydroneopterin 3'-triphosphate 0
                        7,8-dihydroxanthopterin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic molecule 19556
                              organic cyclic compound 19365
                                organic heterocyclic compound 18486
                                  organic heteropolycyclic compound 17874
                                    organic heterobicyclic compound 16808
                                      pteridines 10209
                                        pterins 9372
                                          dihydropterin 4
                                            (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl trihydrogen diphosphate 0
                                            (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin 0
                                            2-amino-4-oxo-6-(erythro-1,2,3-trihydroxypropyl)-7,8-dihydroxypteridine triphosphate 0
                                            2-amino-6-(1-hydroxyethyl)-7-methyl-7,8-dihydropteridin-4-one 0
                                            2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol 0
                                            2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-one + 0
                                            2-amino-6-hydroxymethyl-7,7-dimethyl-7,8-dihydropteridin-4-one 0
                                            6,7-dihydrobiopterin + 0
                                            6-(1,2-dihydroxy-1-methyl-3-triphosphooxypropyl)-7-methyl-7,8-dihydropterin 0
                                            6-pyruvoyl-7,8-dihydropterin 0
                                            7,8-dihydro-D-neopterin 2',3'-cyclic phosphate 0
                                            7,8-dihydrobiopterin + 4
                                            7,8-dihydromonapterin 0
                                            7,8-dihydromonapterin 3-triphosphate 0
                                            7,8-dihydroneopterin + 0
                                            7,8-dihydroneopterin 2'-phosphate 0
                                            7,8-dihydroneopterin 3'-phosphate 0
                                            7,8-dihydroneopterin 3'-triphosphate 0
                                            7,8-dihydroxanthopterin 0
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