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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:azocanes
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Accession:CHEBI:38791 term browser browse the term


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guanethidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Guanethidine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant affects expression
increases expression
EXP Guanethidine affects the expression of ACP5 protein
Guanethidine results in increased expression of ACP5 mRNA
CTD PMID:14527964 NCBI chr 8:23,142,733...23,149,067
Ensembl chr 8:23,142,734...23,148,396
JBrowse link
G Ctsk cathepsin K increases expression
affects expression
EXP Guanethidine results in increased expression of CTSK mRNA
Guanethidine affects the expression of CTSK protein
CTD PMID:14527964 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP Guanethidine inhibits the reaction [Benzo(a)pyrene results in increased activity of CYP1A2 protein] CTD PMID:16510159 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression EXP Guanethidine results in increased expression of MMP13 mRNA CTD PMID:14527964 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Npy neuropeptide Y decreases expression
decreases secretion
EXP
ISO
Guanethidine results in decreased expression of NPY protein
Guanethidine results in decreased secretion of NPY protein
CTD PMID:9460767, PMID:14527964, PMID:15003356 NCBI chr 4:79,557,856...79,565,059
Ensembl chr 4:79,557,854...79,565,097
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO Guanethidine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:15850565 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Th tyrosine hydroxylase decreases expression EXP Guanethidine results in decreased expression of TH protein CTD PMID:9460767 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Vip vasoactive intestinal peptide decreases expression EXP Guanethidine results in decreased expression of VIP protein CTD PMID:14527964 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          nitrogen atom 18565
            nitrogen molecular entity 18565
              organonitrogen compound 18335
                organonitrogen heterocyclic compound 17481
                  azocanes 9
                    azocane + 9
                    guanethidine + 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  organic heteromonocyclic compound 16467
                                    azocanes 9
                                      azocane + 9
                                      guanethidine + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.