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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:thiadiazinane
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Accession:CHEBI:38781 term browser browse the term
Synonyms:related_synonym: thiadiazinanes



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2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aen apoptosis enhancing nuclease increases expression ISO buprofezin results in increased expression of AEN mRNA CTD PMID:36287832 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO buprofezin results in increased expression of AIFM1 mRNA CTD PMID:36287832 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aifm3 apoptosis inducing factor, mitochondria associated 3 increases expression ISO buprofezin results in increased expression of AIFM3 mRNA CTD PMID:36287832 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 increases expression ISO buprofezin results in increased expression of AMBRA1 mRNA CTD PMID:36287832 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Atg10 autophagy related 10 increases expression ISO buprofezin results in increased expression of ATG10 mRNA CTD PMID:36287832 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
JBrowse link
G Atg12 autophagy related 12 increases expression ISO buprofezin results in increased expression of ATG12 mRNA CTD PMID:36287832 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg5 autophagy related 5 increases expression ISO buprofezin results in increased expression of ATG5 mRNA CTD PMID:36287832 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 increases expression ISO buprofezin results in increased expression of ATG7 mRNA CTD PMID:36287832 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 decreases expression ISO buprofezin results in decreased expression of ATP2B4 mRNA CTD PMID:36287832 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO buprofezin results in increased expression of BAX protein CTD PMID:36287832 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO buprofezin results in decreased expression of BCL2 mRNA; buprofezin results in decreased expression of BCL2 protein CTD PMID:36287832 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Becn1 beclin 1 increases expression ISO buprofezin results in increased expression of BECN1 protein CTD PMID:36287832 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bok BCL2 family apoptosis regulator BOK increases expression ISO buprofezin results in increased expression of BOK mRNA CTD PMID:36287832 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO buprofezin results in decreased expression of CAAP1 mRNA CTD PMID:36287832 NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
JBrowse link
G Casp3 caspase 3 increases activity ISO buprofezin results in increased activity of CASP3 protein CTD PMID:36287832 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO buprofezin results in increased activity of CASP9 protein CTD PMID:36287832 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases activity ISO buprofezin results in decreased activity of CAT protein CTD PMID:31199169 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyct cytochrome c, testis increases localization ISO buprofezin results in increased localization of CYCT protein CTD PMID:36287832 NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO buprofezin results in increased expression of GOT1 protein CTD PMID:31199169 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression ISO buprofezin results in increased expression of GPT protein CTD PMID:31199169 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO buprofezin results in increased lipidation of and results in increased localization of MAP1LC3B protein CTD PMID:36287832 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO buprofezin results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO buprofezin results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Sod1 superoxide dismutase 1 decreases activity ISO buprofezin results in decreased activity of SOD1 protein CTD PMID:31199169 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO buprofezin results in decreased expression of SQSTM1 protein CTD PMID:36287832 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 decreases expression ISO buprofezin results in decreased expression of TRIAP1 mRNA CTD PMID:36287832 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042
JBrowse link
buprofezin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aen apoptosis enhancing nuclease increases expression ISO buprofezin results in increased expression of AEN mRNA CTD PMID:36287832 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO buprofezin results in increased expression of AIFM1 mRNA CTD PMID:36287832 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Aifm3 apoptosis inducing factor, mitochondria associated 3 increases expression ISO buprofezin results in increased expression of AIFM3 mRNA CTD PMID:36287832 NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 increases expression ISO buprofezin results in increased expression of AMBRA1 mRNA CTD PMID:36287832 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
JBrowse link
G Atg10 autophagy related 10 increases expression ISO buprofezin results in increased expression of ATG10 mRNA CTD PMID:36287832 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
JBrowse link
G Atg12 autophagy related 12 increases expression ISO buprofezin results in increased expression of ATG12 mRNA CTD PMID:36287832 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
JBrowse link
G Atg5 autophagy related 5 increases expression ISO buprofezin results in increased expression of ATG5 mRNA CTD PMID:36287832 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 increases expression ISO buprofezin results in increased expression of ATG7 mRNA CTD PMID:36287832 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 decreases expression ISO buprofezin results in decreased expression of ATP2B4 mRNA CTD PMID:36287832 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO buprofezin results in increased expression of BAX protein CTD PMID:36287832 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO buprofezin results in decreased expression of BCL2 mRNA; buprofezin results in decreased expression of BCL2 protein CTD PMID:36287832 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Becn1 beclin 1 increases expression ISO buprofezin results in increased expression of BECN1 protein CTD PMID:36287832 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bok BCL2 family apoptosis regulator BOK increases expression ISO buprofezin results in increased expression of BOK mRNA CTD PMID:36287832 NCBI chr 9:94,223,493...94,234,476
Ensembl chr 9:94,223,389...94,234,476
JBrowse link
G Caap1 caspase activity and apoptosis inhibitor 1 decreases expression ISO buprofezin results in decreased expression of CAAP1 mRNA CTD PMID:36287832 NCBI chr 5:109,313,253...109,414,323
Ensembl chr 5:109,361,912...109,414,314
JBrowse link
G Casp3 caspase 3 increases activity ISO buprofezin results in increased activity of CASP3 protein CTD PMID:36287832 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO buprofezin results in increased activity of CASP9 protein CTD PMID:36287832 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases activity ISO buprofezin results in decreased activity of CAT protein CTD PMID:31199169 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyct cytochrome c, testis increases localization ISO buprofezin results in increased localization of CYCT protein CTD PMID:36287832 NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression ISO buprofezin results in increased expression of GOT1 protein CTD PMID:31199169 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression ISO buprofezin results in increased expression of GPT protein CTD PMID:31199169 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO buprofezin results in increased lipidation of and results in increased localization of MAP1LC3B protein CTD PMID:36287832 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO buprofezin results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO buprofezin results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Sod1 superoxide dismutase 1 decreases activity ISO buprofezin results in decreased activity of SOD1 protein CTD PMID:31199169 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sqstm1 sequestosome 1 decreases expression ISO buprofezin results in decreased expression of SQSTM1 protein CTD PMID:36287832 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 decreases expression ISO buprofezin results in decreased expression of TRIAP1 mRNA CTD PMID:36287832 NCBI chr12:41,267,534...41,270,053
Ensembl chr12:41,267,549...41,270,042
JBrowse link
dazomet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO dazomet results in increased activity of NFE2L2 protein CTD PMID:20143881 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    chemical entity 19829
      atom 19829
        nonmetal atom 19767
          nitrogen atom 18955
            nitrogen molecular entity 18955
              organonitrogen compound 18804
                organonitrogen heterocyclic compound 18148
                  thiadiazinane 27
                    1,3,5-thiadiazinane 0
                    2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one + 26
                    3-(2-furanylmethyl)-5-(2-methoxyethyl)-1,3,5-thiadiazinane-2-thione 0
                    5-tert-butyl-3-(phenylmethyl)-1,3,5-thiadiazinane-2-thione 0
                    Thiadiazin 0
                    dazomet 1
                    taurolidine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            organic molecule 19677
                              organic cyclic compound 19490
                                organic heterocyclic compound 18852
                                  organic heteromonocyclic compound 17794
                                    thiadiazinane 27
                                      1,3,5-thiadiazinane 0
                                      2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one + 26
                                      3-(2-furanylmethyl)-5-(2-methoxyethyl)-1,3,5-thiadiazinane-2-thione 0
                                      5-tert-butyl-3-(phenylmethyl)-1,3,5-thiadiazinane-2-thione 0
                                      Thiadiazin 0
                                      dazomet 1
                                      taurolidine 0
paths to the root