CHEBI ONTOLOGY - ANNOTATIONS |
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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
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Term: | benzothiophenes |
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Accession: | CHEBI:38767
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browse the term
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Synonyms: | alt_id: | CHEBI:38766 |
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Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
benzothiophene analog binds to and results in increased activity of ESR1 protein |
CTD |
PMID:15713417 |
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NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
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Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
ISO |
LY 117018 results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:15876410 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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Esr1 |
estrogen receptor 1 |
affects binding |
ISO |
LY 117018 binds to ESR1 protein |
CTD |
PMID:10397250 |
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NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
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Mapk1 |
mitogen activated protein kinase 1 |
increases phosphorylation multiple interactions |
ISO |
LY 117018 results in increased phosphorylation of MAPK1 protein U 0126 inhibits the reaction [LY 117018 results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:17174166 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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Mapk3 |
mitogen activated protein kinase 3 |
increases phosphorylation multiple interactions |
ISO |
LY 117018 results in increased phosphorylation of MAPK3 protein U 0126 inhibits the reaction [LY 117018 results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:17174166 |
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NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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Ptpn13 |
protein tyrosine phosphatase, non-receptor type 13 |
increases expression |
ISO |
LY 117018 results in increased expression of PTPN13 mRNA |
CTD |
PMID:15876410 |
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NCBI chr14:7,688,551...7,863,664
Ensembl chr14:7,688,551...7,863,664
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Rbm17 |
RNA binding motif protein 17 |
multiple interactions |
ISO |
LY 117018 inhibits the reaction [RBM17 protein results in decreased susceptibility to Mitoxantrone] |
CTD |
PMID:16061639 |
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NCBI chr17:70,586,345...70,603,289
Ensembl chr17:70,586,394...70,603,267
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Aatk |
apoptosis-associated tyrosine kinase |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of AATK mRNA |
CTD |
PMID:15576828 |
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NCBI chr10:109,184,338...109,224,455
Ensembl chr10:109,188,112...109,224,370
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Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases expression affects activity multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of ABCB1 mRNA; Raloxifene Hydrochloride results in decreased expression of ABCB1 protein ABCB1 protein affects the activity of Raloxifene Hydrochloride [Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 mRNA; [Cyclosporine co-treated with Raloxifene Hydrochloride] results in decreased expression of ABCB1 protein |
CTD |
PMID:16959878 PMID:17096884 |
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NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
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Abcb9 |
ATP binding cassette subfamily B member 9 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABCB9 mRNA |
CTD |
PMID:14699072 |
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NCBI chr12:37,923,974...37,956,678
Ensembl chr12:37,923,528...37,958,363
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Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
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Abcg1 |
ATP binding cassette subfamily G member 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABCG1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489
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Abhd2 |
abhydrolase domain containing 2, acylglycerol lipase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ABHD2 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 1:140,998,240...141,087,405
Ensembl chr 1:140,998,240...141,087,405
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Abhd5 |
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABHD5 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 8:130,973,222...131,001,448
Ensembl chr 8:130,973,201...131,001,458
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Ablim3 |
actin binding LIM protein family, member 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ABLIM3 mRNA |
CTD |
PMID:14699072 |
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NCBI chr18:57,126,534...57,245,965
Ensembl chr18:57,128,399...57,245,666
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Ace |
angiotensin I converting enzyme |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ACE mRNA |
CTD |
PMID:15849065 |
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NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
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Ackr3 |
atypical chemokine receptor 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of ACKR3 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
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Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
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Acvrl1 |
activin A receptor like type 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ACVRL1 mRNA; Raloxifene Hydrochloride results in increased expression of ACVRL1 protein |
CTD |
PMID:20135064 |
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NCBI chr 7:142,769,942...142,787,336
Ensembl chr 7:142,776,252...142,787,335
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Adam19 |
ADAM metallopeptidase domain 19 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
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Adam22 |
ADAM metallopeptidase domain 22 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ADAM22 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 4:22,864,485...23,002,969
Ensembl chr 4:22,859,622...22,996,645
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Adamtsl3 |
ADAMTS-like 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADAMTSL3 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:144,238,958...144,561,065
Ensembl chr 1:144,239,020...144,561,247
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Adcy2 |
adenylate cyclase 2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ADCY2 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
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Adcyap1 |
adenylate cyclase activating polypeptide 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ADCYAP1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
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Adgra3 |
adhesion G protein-coupled receptor A3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADGRA3 mRNA |
CTD |
PMID:19429434 |
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NCBI chr14:64,686,677...64,786,813
Ensembl chr14:64,686,793...64,786,497
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Adgrb2 |
adhesion G protein-coupled receptor B2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADGRB2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 5:148,168,530...148,231,587
Ensembl chr 5:148,193,710...148,231,587
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Adgrg1 |
adhesion G protein-coupled receptor G1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ADGRG1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
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Adh1 |
alcohol dehydrogenase 1 (class I) |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of ADH1 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
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Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADIPOQ mRNA |
CTD |
PMID:16643890 |
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NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
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Adora2a |
adenosine A2a receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ADORA2A mRNA |
CTD |
PMID:15849065 |
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NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
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Adora2b |
adenosine A2B receptor |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
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Adra1a |
adrenoceptor alpha 1A |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of ADRA1A mRNA |
CTD |
PMID:20201831 |
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NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
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Aebp1 |
AE binding protein 1 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of AEBP1 mRNA |
CTD |
PMID:15576828 |
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NCBI chr14:86,101,253...86,111,323
Ensembl chr14:86,101,277...86,111,306
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Ago2 |
argonaute RISC catalytic component 2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of AGO2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
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Agt |
angiotensinogen |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein]] |
CTD |
PMID:17336289 |
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NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
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Ahcyl1 |
adenosylhomocysteinase-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AHCYL1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761
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Ahnak |
AHNAK nucleoprotein |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of AHNAK mRNA |
CTD |
PMID:16514628 |
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NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015
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Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Raloxifene Hydrochloride results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA |
CTD |
PMID:19901195 |
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NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
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Aimp1 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of AIMP1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 2:237,727,782...237,751,327
Ensembl chr 2:237,727,764...237,751,378
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Ak3 |
adenylate kinase 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of AK3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
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Akap1 |
A-kinase anchoring protein 1 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA Raloxifene Hydrochloride affects the expression of AKAP1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276
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Akr7a2 |
aldo-keto reductase family 7, member A2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of AKR7A2 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
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Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation increases phosphorylation |
ISO EXP |
Raloxifene Hydrochloride results in decreased phosphorylation of AKT1 protein Raloxifene Hydrochloride results in increased phosphorylation of AKT1 protein |
CTD |
PMID:15590986 PMID:15876410 PMID:16798746 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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Alad |
aminolevulinate dehydratase |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ALAD mRNA |
CTD |
PMID:26865669 |
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NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
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Alas2 |
5'-aminolevulinate synthase 2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ALAS2 mRNA |
CTD |
PMID:16079270 |
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NCBI chr X:23,167,576...23,187,356
Ensembl chr X:23,167,696...23,187,341
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Alcam |
activated leukocyte cell adhesion molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ALCAM mRNA] |
CTD |
PMID:21185374 |
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NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
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Amigo2 |
adhesion molecule with Ig like domain 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 7:138,704,124...138,707,221
Ensembl chr 7:138,704,126...138,707,221
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Amotl2 |
angiomotin like 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AMOTL2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 8:111,210,261...111,226,217
Ensembl chr 8:111,209,908...111,226,226
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Ang |
angiogenin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ANG mRNA |
CTD |
PMID:19429434 |
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NCBI chr15:28,022,926...28,028,636
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Angptl2 |
angiopoietin-like 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ANGPTL2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 3:12,262,822...12,292,665
Ensembl chr 3:12,262,822...12,292,663
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Angptl7 |
angiopoietin like 7 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ANGPTL7 mRNA |
CTD |
PMID:16202921 |
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NCBI chr 5:165,311,794...165,318,361
Ensembl chr 5:165,312,130...165,316,652
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Ank3 |
ankyrin 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ANK3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
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Ankrd1 |
ankyrin repeat domain 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
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Ankrd28 |
ankyrin repeat domain 28 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ANKRD28 mRNA |
CTD |
PMID:19059307 |
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NCBI chr16:7,816,876...7,879,023
Ensembl chr16:7,818,667...7,928,518
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Aopep |
aminopeptidase O |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of AOPEP mRNA |
CTD |
PMID:21185374 |
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NCBI chr17:507,389...825,062
Ensembl chr17:507,377...821,582
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Aox1 |
aldehyde oxidase 1 |
multiple interactions decreases activity |
ISO |
Raloxifene Hydrochloride inhibits the reaction [AOX1 protein results in increased metabolism of zoniporide] Raloxifene Hydrochloride results in decreased activity of AOX1 protein |
CTD |
PMID:20040581 |
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NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
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Ap1g1 |
adaptor related protein complex 1 subunit gamma 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of AP1G1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr19:41,805,252...41,860,076
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Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions increases expression |
EXP |
[Raloxifene Hydrochloride co-treated with Kainic Acid] results in increased expression of APEX1 mRNA Raloxifene Hydrochloride results in increased expression of APEX1 mRNA |
CTD |
PMID:16120186 |
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NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
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Apod |
apolipoprotein D |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of APOD mRNA |
CTD |
PMID:16514628 |
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NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
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App |
amyloid beta precursor protein |
multiple interactions affects binding |
ISO |
Raloxifene Hydrochloride inhibits the reaction [APP protein results in increased expression of TGFB1 mRNA]; Raloxifene Hydrochloride inhibits the reaction [APP protein results in increased expression of TNF mRNA] Raloxifene Hydrochloride binds to APP protein |
CTD |
PMID:31583774 |
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NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
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Ar |
androgen receptor |
decreases expression |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of AR mRNA Raloxifene Hydrochloride results in decreased expression of AR protein |
CTD |
PMID:11867264 PMID:15731164 PMID:16837883 |
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NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
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Areg |
amphiregulin |
multiple interactions increases expression decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA Raloxifene Hydrochloride results in increased expression of AREG mRNA Raloxifene Hydrochloride inhibits the reaction [Estrogens, Conjugated (USP) results in increased expression of AREG mRNA] Raloxifene Hydrochloride results in decreased expression of AREG mRNA |
CTD |
PMID:16514628 PMID:19022889 PMID:19059307 PMID:26865669 |
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NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
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Arg2 |
arginase 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ARG2 mRNA |
CTD |
PMID:22841776 |
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NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
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Arhgap29 |
Rho GTPase activating protein 29 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ARHGAP29 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 2:225,552,075...225,613,349
Ensembl chr 2:225,552,148...225,613,359
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Arid5a |
AT-rich interaction domain 5A |
multiple interactions |
ISO |
ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein] |
CTD |
PMID:15941852 |
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NCBI chr 9:42,871,907...42,886,725
Ensembl chr 9:42,871,950...42,884,855
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Arid5b |
AT-rich interaction domain 5B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ARID5B mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:21,713,900...21,881,193
Ensembl chr20:21,564,975...21,880,715
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Arl1 |
ADP-ribosylation factor like GTPase 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ARL1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 7:29,282,411...29,293,455
Ensembl chr 7:29,282,305...29,293,399
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G |
Arl4c |
ADP ribosylation factor like GTPase 4C |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA Raloxifene Hydrochloride affects the expression of ARL4C mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094
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G |
Arnt2 |
aryl hydrocarbon receptor nuclear translocator 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ARNT2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171
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G |
Asb13 |
ankyrin repeat and SOCS box-containing 13 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr17:70,215,401...70,234,103
Ensembl chr17:70,215,401...70,234,103
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ASNS mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA Raloxifene Hydrochloride results in increased expression of ATF3 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
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NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ATF7IP mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:170,476,998...170,563,063
Ensembl chr 4:170,518,673...170,559,532
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G |
Atp1a1 |
ATPase Na+/K+ transporting subunit alpha 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ATP1A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
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G |
Atp9a |
ATPase phospholipid transporting 9A (putative) |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ATP9A mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:165,405,588...165,511,104
Ensembl chr 3:165,412,803...165,477,771
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G |
Aurka |
aurora kinase A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of AURKA mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
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G |
Bad |
BCL2-associated agonist of cell death |
increases cleavage |
ISO |
Raloxifene Hydrochloride results in increased cleavage of BAD protein |
CTD |
PMID:12084714 |
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NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
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G |
Bak1 |
BCL2-antagonist/killer 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BAK1 mRNA |
CTD |
PMID:16202921 |
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NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
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G |
Bax |
BCL2 associated X, apoptosis regulator |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of BAX protein |
CTD |
PMID:16009171 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
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G |
Bcas1 |
brain enriched myelin associated protein 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of BCAS1 mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 3:167,957,994...168,033,462
Ensembl chr 3:167,957,994...168,033,457
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G |
Bcl2 |
BCL2, apoptosis regulator |
affects expression increases expression decreases expression |
ISO |
Raloxifene Hydrochloride affects the expression of BCL2 protein Raloxifene Hydrochloride results in increased expression of BCL2 protein Raloxifene Hydrochloride results in decreased expression of BCL2 mRNA; Raloxifene Hydrochloride results in decreased expression of BCL2 protein |
CTD |
PMID:16009171 PMID:16566921 PMID:16973256 PMID:17220163 PMID:20945400 |
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NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
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G |
Bcl2l11 |
BCL2 like 11 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BCL2L11 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
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G |
Bcl3 |
BCL3, transcription coactivator |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA] |
CTD |
PMID:12072388 |
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NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
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G |
Bcl6 |
BCL6, transcription repressor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of BCL6 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr11:80,255,790...80,279,075
Ensembl chr11:80,255,790...80,279,075
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G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BGLAP protein |
CTD |
PMID:17823083 |
|
NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
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G |
Bgn |
biglycan |
increases expression |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of BGN mRNA |
CTD |
PMID:15576828 PMID:19429434 |
|
NCBI chr X:157,319,042...157,331,204
Ensembl chr X:157,319,046...157,331,204
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
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G |
Blzf1 |
basic leucine zipper nuclear factor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of BLZF1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr13:82,592,170...82,607,379
Ensembl chr13:82,592,170...82,607,379
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G |
Bmp7 |
bone morphogenetic protein 7 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of BMP7 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
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G |
Brinp2 |
BMP/retinoic acid inducible neural specific 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of BRINP2 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr13:75,948,679...76,049,363
Ensembl chr13:75,948,679...76,049,363
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G |
C1qb |
complement C1q B chain |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of C1QB mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
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G |
C2cd2 |
C2 calcium-dependent domain containing 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA Raloxifene Hydrochloride affects the expression of C2CD2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr11:38,354,746...38,420,133
Ensembl chr11:38,357,424...38,420,119
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G |
C3 |
complement C3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of C3 mRNA |
CTD |
PMID:12370124 |
|
NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
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G |
Ca12 |
carbonic anhydrase 12 |
affects expression decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of CA12 mRNA Raloxifene Hydrochloride results in decreased expression of CA12 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA |
CTD |
PMID:14699072 PMID:19059307 PMID:26865669 |
|
NCBI chr 8:72,405,770...72,461,425
Ensembl chr 8:72,405,748...72,460,240
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G |
Ca4 |
carbonic anhydrase 4 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CA4 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
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G |
Cabin1 |
calcineurin binding protein 1 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of CABIN1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr20:13,836,032...13,963,003
Ensembl chr20:13,836,030...13,963,003
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G |
Cacna1h |
calcium voltage-gated channel subunit alpha1 H |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CACNA1H mRNA |
CTD |
PMID:21228613 |
|
NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
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G |
Cacna1i |
calcium voltage-gated channel subunit alpha1 I |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CACNA1I mRNA |
CTD |
PMID:21228613 |
|
NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
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G |
Calb2 |
calbindin 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CALB2 mRNA |
CTD |
PMID:17962382 |
|
NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
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G |
Cald1 |
caldesmon 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CALD1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
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G |
Cap2 |
cyclase associated actin cytoskeleton regulatory protein 2 |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of CAP2 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr17:18,441,614...18,592,866
Ensembl chr17:18,442,127...18,592,750
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G |
Capn2 |
calpain 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CAPN2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
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G |
Card10 |
caspase recruitment domain family, member 10 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CARD10 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:119,998,639...120,028,632
Ensembl chr 7:119,999,472...120,027,026
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G |
Caskin2 |
cask-interacting protein 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:104,344,035...104,358,256
Ensembl chr10:104,344,099...104,358,253
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G |
Casp3 |
caspase 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CASP3 protein modified form |
CTD |
PMID:20945400 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Casp4 |
caspase 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CASP4 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
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G |
Casp7 |
caspase 7 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA Raloxifene Hydrochloride affects the expression of CASP7 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
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G |
Cat |
catalase |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of CAT protein |
CTD |
PMID:17227729 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
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G |
Cav1 |
caveolin 1 |
affects expression increases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride affects the expression of CAV1 mRNA Raloxifene Hydrochloride results in increased expression of CAV1 mRNA; Raloxifene Hydrochloride results in increased expression of CAV1 protein fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 mRNA]; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of CAV1 protein] |
CTD |
PMID:14699072 PMID:17091190 |
|
NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
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G |
Cbx1 |
chromobox 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CBX1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr10:84,656,698...84,677,112
Ensembl chr10:84,669,914...84,675,741
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G |
Cbx3 |
chromobox 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CBX3 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:81,243,809...81,257,898
Ensembl chr 4:81,244,469...81,257,897
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases activity affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA; fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased activity of CCL2 protein] Raloxifene Hydrochloride affects the expression of CCL2 mRNA |
CTD |
PMID:14699072 PMID:17006379 PMID:19059307 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of CCL20 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to CCL3 promoter]; Raloxifene Hydrochloride inhibits the reaction [RELA protein binds to CCL3 promoter] Raloxifene Hydrochloride results in decreased expression of CCL3 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression decreases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCL5 mRNA Raloxifene Hydrochloride results in decreased expression of CCL5 protein |
CTD |
PMID:12154049 PMID:16842799 |
|
NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
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G |
Ccn3 |
cellular communication network factor 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CCN3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
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G |
Ccna2 |
cyclin A2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNA2 mRNA; Raloxifene Hydrochloride results in increased expression of CCNA2 protein |
CTD |
PMID:17445807 |
|
NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
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G |
Ccnb1 |
cyclin B1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNB1 mRNA; Raloxifene Hydrochloride results in increased expression of CCNB1 protein |
CTD |
PMID:12154049 PMID:17445807 |
|
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
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G |
Ccnd1 |
cyclin D1 |
multiple interactions decreases expression affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA Raloxifene Hydrochloride results in decreased expression of CCND1 mRNA Raloxifene Hydrochloride affects the expression of CCND1 mRNA |
CTD |
PMID:14699072 PMID:19059307 PMID:26865669 |
|
NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
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G |
Ccng2 |
cyclin G2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CCNG2 mRNA |
CTD |
PMID:16497877 PMID:26865669 |
|
NCBI chr14:16,267,572...16,276,068
Ensembl chr14:16,267,573...16,276,068
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G |
Cd200 |
Cd200 molecule |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of CD200 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr11:60,371,617...60,398,450
Ensembl chr11:60,371,684...60,403,196
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G |
Cd24 |
CD24 molecule |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CD24 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
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|
G |
Cd3g |
CD3g molecule |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CD3G mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 8:49,274,553...49,280,943
Ensembl chr 8:49,274,960...49,280,901
|
|
G |
Cd40 |
CD40 molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein] |
CTD |
PMID:16081843 |
|
NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
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|
G |
Cd44 |
CD44 molecule (Indian blood group) |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CD44 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
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G |
Cd52 |
CD52 molecule |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CD52 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 5:152,322,910...152,324,469
Ensembl chr 5:152,322,916...152,324,469
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G |
Cd74 |
CD74 molecule |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CD74 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
|
|
G |
Cd80 |
Cd80 molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] |
CTD |
PMID:16081843 |
|
NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
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|
G |
Cd86 |
CD86 molecule |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] |
CTD |
PMID:16081843 |
|
NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
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G |
Cd8a |
CD8a molecule |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CD8A mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 4:99,217,640...99,243,352
Ensembl chr 4:99,239,115...99,243,351
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|
G |
Cdh2 |
cadherin 2 |
affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride affects the expression of CDH2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA |
CTD |
PMID:14699072 PMID:16079270 PMID:19059307 |
|
NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
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G |
Cdh6 |
cadherin 6 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CDH6 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 2:63,100,723...63,246,618
Ensembl chr 2:63,101,739...63,166,509
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G |
Cdk5r1 |
cyclin-dependent kinase 5 regulatory subunit 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
|
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G |
Cdk5rap3 |
CDK5 regulatory subunit associated protein 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CDK5RAP3 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:84,780,644...84,789,800
Ensembl chr10:84,780,608...84,789,832
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CDKN1A mRNA; Raloxifene Hydrochloride results in increased expression of CDKN1A protein |
CTD |
PMID:12154049 PMID:16497877 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CDKN1B protein |
CTD |
PMID:16536755 |
|
NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
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|
G |
Cdo1 |
cysteine dioxygenase type 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
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|
G |
Cdon |
cell adhesion associated, oncogene regulated |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CDON mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 8:36,625,757...36,712,091
Ensembl chr 8:36,625,733...36,710,949
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CEBPA mRNA |
CTD |
PMID:15849065 |
|
NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
affects expression increases expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of CEBPB mRNA Raloxifene Hydrochloride results in increased expression of CEBPB mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA |
CTD |
PMID:14699072 PMID:16497877 PMID:19059307 |
|
NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
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|
G |
Cenpa |
centromere protein A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CENPA mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 6:27,072,259...27,080,863
Ensembl chr 6:27,072,166...27,080,856
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|
G |
Cers6 |
ceramide synthase 6 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 3:55,094,240...55,338,370
Ensembl chr 3:55,094,637...55,338,445
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|
G |
Cfd |
complement factor D |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of CFD mRNA |
CTD |
PMID:15576828 |
|
NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
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|
G |
Chrd |
chordin |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CHRD mRNA |
CTD |
PMID:14699072 |
|
NCBI chr11:83,858,503...83,867,543
Ensembl chr11:83,858,503...83,867,203
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|
G |
Cish |
cytokine inducible SH2-containing protein |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CISH mRNA] |
CTD |
PMID:12072388 |
|
NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
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|
G |
Ckb |
creatine kinase B |
increases activity multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in increased activity of CKB protein Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased activity of CKB protein] |
CTD |
PMID:16621514 PMID:17029789 |
|
NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
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G |
Clcn4 |
chloride voltage-gated channel 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr X:25,016,177...25,082,563
Ensembl chr X:25,016,401...25,080,410
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|
G |
Clcn6 |
chloride voltage-gated channel 6 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLCN6 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 5:164,811,815...164,844,554
Ensembl chr 5:164,811,816...164,844,586
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|
G |
Clic4 |
chloride intracellular channel 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLIC4 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
|
|
G |
Clk1 |
CDC-like kinase 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLK1 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 9:65,296,777...65,308,017
Ensembl chr 9:65,296,778...65,307,995
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|
G |
Clmn |
calmin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLMN mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 6:128,473,592...128,567,267
Ensembl chr 6:128,473,570...128,567,198
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|
G |
Clstn1 |
calsyntenin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CLSTN1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 5:166,533,262...166,601,686
Ensembl chr 5:166,533,181...166,601,684
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G |
Cltb |
clathrin, light chain B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CLTB mRNA |
CTD |
PMID:14699072 |
|
NCBI chr17:10,537,348...10,554,999
Ensembl chr17:10,537,365...10,554,989
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|
G |
Clu |
clusterin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CLU mRNA |
CTD |
PMID:12370124 PMID:16202921 |
|
NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
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|
G |
Cnbp |
CCHC-type zinc finger, nucleic acid binding protein |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CNBP mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 4:119,747,890...119,756,787
Ensembl chr 4:119,747,911...119,756,765
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|
G |
Col11a1 |
collagen type XI alpha 1 chain |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of COL11A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
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G |
Col1a2 |
collagen type I alpha 2 chain |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of COL1A2 mRNA |
CTD |
PMID:19401787 |
|
NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
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|
G |
Col26a1 |
collagen type XXVI alpha 1 chain |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of COL26A1 mRNA |
CTD |
PMID:17962382 |
|
NCBI chr12:22,834,866...22,980,603
Ensembl chr12:22,835,019...22,980,603
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G |
Col5a1 |
collagen type V alpha 1 chain |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of COL5A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
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G |
Col5a2 |
collagen type V alpha 2 chain |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of COL5A2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
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G |
Copb2 |
COPI coat complex subunit beta 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of COPB2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 8:106,582,339...106,603,763
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|
G |
Cpb2 |
carboxypeptidase B2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CPB2 protein |
CTD |
PMID:16167916 |
|
NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
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G |
Cpe |
carboxypeptidase E |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CPE mRNA |
CTD |
PMID:16079270 |
|
NCBI chr16:26,906,716...27,014,811
Ensembl chr16:26,906,716...27,014,813
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G |
Cpm |
carboxypeptidase M |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CPM mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 7:60,654,350...60,714,620
Ensembl chr 7:60,654,350...60,714,620
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G |
Creb1 |
cAMP responsive element binding protein 1 |
increases phosphorylation |
EXP |
Raloxifene Hydrochloride results in increased phosphorylation of CREB protein |
CTD |
PMID:24782323 |
|
NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
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G |
Crebbp |
CREB binding protein |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to PTGS2 promoter] |
CTD |
PMID:17872375 |
|
NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
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|
G |
Crispld2 |
cysteine-rich secretory protein LCCL domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
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G |
Crybb2 |
crystallin, beta B2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CRYBB2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr12:49,577,580...49,588,555
Ensembl chr12:49,578,633...49,588,555
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|
G |
Csdc2 |
cold shock domain containing C2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:123,168,811...123,183,336
Ensembl chr 7:123,168,811...123,183,335
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G |
Csf1 |
colony stimulating factor 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CSF1 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 2:210,522,370...210,550,546
Ensembl chr 2:210,522,375...210,550,560
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
EXP |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of CSF1R protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of CSF1R protein |
CTD |
PMID:31332895 |
|
NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
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|
G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CSF2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
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G |
Csf3 |
colony stimulating factor 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CSF3 mRNA |
CTD |
PMID:16298037 |
|
NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
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G |
Ctsb |
cathepsin B |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CTSB mRNA |
CTD |
PMID:16079270 |
|
NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
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G |
Ctsh |
cathepsin H |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CTSH mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
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G |
Ctsk |
cathepsin K |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CTSK mRNA |
CTD |
PMID:17166402 |
|
NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
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G |
Cuedc1 |
CUE domain containing 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:75,495,817...75,516,280
Ensembl chr10:75,495,817...75,516,304
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G |
Cxadr |
CXADR, Ig-like cell adhesion molecule |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of CXADR mRNA |
CTD |
PMID:14699072 |
|
NCBI chr11:16,826,269...16,873,564
Ensembl chr11:16,826,399...16,873,562
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of CXCL10 protein] |
CTD |
PMID:19533603 |
|
NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
|
|
G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of CXCL12 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased secretion of CXCL12 protein] Raloxifene Hydrochloride results in decreased expression of CXCL12 mRNA |
CTD |
PMID:19059307 PMID:20549624 PMID:21185374 PMID:26865669 |
|
NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CXCL5 mRNA] |
CTD |
PMID:12072388 |
|
NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
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G |
Cylc2 |
cylicin 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CYLC2 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 5:66,292,607...66,327,552
Ensembl chr 5:66,313,815...66,322,567
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA Raloxifene Hydrochloride results in decreased expression of CYP19A1 mRNA |
CTD |
PMID:10704911 PMID:19059307 |
|
NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO EXP |
[Raloxifene Hydrochloride results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; Raloxifene Hydrochloride inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] Raloxifene Hydrochloride results in increased expression of CYP1A1 mRNA |
CTD |
PMID:18493746 PMID:19901195 |
|
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of CYP26A1 mRNA |
CTD |
PMID:29990529 |
|
NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CYP27A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
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G |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of CYP27B1 mRNA |
CTD |
PMID:15795327 |
|
NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
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G |
Cyp2a1 |
cytochrome P450, family 2, subfamily a, polypeptide 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of CYP2A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
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G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
decreases activity |
ISO |
Raloxifene Hydrochloride results in decreased activity of CYP2C8 protein |
CTD |
PMID:15601807 |
|
NCBI chr 1:147,236,480...147,307,988
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|
G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
multiple interactions decreases activity |
ISO |
Raloxifene Hydrochloride inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin] Raloxifene Hydrochloride results in decreased activity of CYP3A4 protein |
CTD |
PMID:15860655 PMID:19299527 PMID:23721565 |
|
NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
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G |
Dact1 |
dishevelled-binding antagonist of beta-catenin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:93,740,440...93,751,003
Ensembl chr 6:93,740,586...93,749,809
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G |
Dag1 |
dystroglycan 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DAG1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 8:116,980,501...116,993,182
Ensembl chr 8:116,980,497...116,993,193
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G |
Daxx |
death-domain associated protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DAXX mRNA |
CTD |
PMID:14699072 |
|
NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
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G |
Dbp |
D-box binding PAR bZIP transcription factor |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of DBP mRNA |
CTD |
PMID:15576828 |
|
NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
|
|
G |
Dcbld2 |
discoidin, CUB and LCCL domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr11:44,237,814...44,292,884
Ensembl chr11:44,241,111...44,292,884
|
|
G |
Ddit4 |
DNA-damage-inducible transcript 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DDIT4 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
|
|
G |
Ddx21 |
DExD-box helicase 21 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DDX21 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr20:32,213,147...32,232,632
Ensembl chr20:32,213,148...32,232,632
|
|
G |
Ddx3 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DDX3Y mRNA |
CTD |
PMID:16514628 |
|
NCBI chr Y:1,217,800...1,238,454
Ensembl chr Y:1,217,800...1,238,420
|
|
G |
Ddx50 |
DExD-box helicase 50 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of DDX50 mRNA |
CTD |
PMID:16079270 |
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NCBI chr20:32,239,736...32,269,522
Ensembl chr20:32,239,748...32,269,145
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G |
Defb1 |
defensin beta 1 |
multiple interactions |
ISO |
[Progesterone co-treated with Raloxifene Hydrochloride] results in increased expression of DEFB1 mRNA |
CTD |
PMID:18367319 |
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NCBI chr16:75,294,385...75,309,127
Ensembl chr16:75,294,376...75,309,176
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G |
Depp1 |
DEPP1, autophagy regulator |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DEPP1 mRNA |
CTD |
PMID:16298037 |
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NCBI chr 4:148,780,330...148,784,566
Ensembl chr 4:148,782,479...148,784,562
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G |
Dhcr24 |
24-dehydrocholesterol reductase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DHCR24 mRNA |
CTD |
PMID:15585566 |
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NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
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G |
Dhrs2 |
dehydrogenase/reductase 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of DHRS2 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr15:33,876,701...33,891,559
Ensembl chr15:33,885,106...33,891,539
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G |
Dhx9 |
DExH-box helicase 9 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DHX9 mRNA |
CTD |
PMID:16514628 |
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NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
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G |
Dicer1 |
dicer 1 ribonuclease III |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DICER1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 6:128,388,084...128,453,234
Ensembl chr 6:128,388,053...128,434,183
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G |
Dkk2 |
dickkopf WNT signaling pathway inhibitor 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DKK2 mRNA |
CTD |
PMID:19429434 |
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NCBI chr 2:237,148,918...237,240,883
Ensembl chr 2:237,148,941...237,241,350
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G |
Dmbt1 |
deleted in malignant brain tumors 1 |
increases expression |
EXP ISO |
Raloxifene Hydrochloride results in increased expression of DMBT1 mRNA; Raloxifene Hydrochloride results in increased expression of DMBT1 protein |
CTD |
PMID:15564322 |
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NCBI chr 1:201,620,642...201,689,905 NCBI chr 1:203,149,414...203,228,705
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G |
Dnaja1 |
DnaJ heat shock protein family (Hsp40) member A1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DNAJA1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 5:57,028,467...57,039,378
Ensembl chr 5:57,028,467...57,039,378
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
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G |
Dnajb4 |
DnaJ heat shock protein family (Hsp40) member B4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB4 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 2:257,394,692...257,425,344
Ensembl chr 2:257,394,818...257,425,242
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DNAJB9 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
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G |
Dnmbp |
dynamin binding protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DNMBP mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:263,625,503...263,718,784
Ensembl chr 1:263,625,501...263,718,745
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G |
Dock9 |
dedicator of cytokinesis 9 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA |
CTD |
PMID:19059307 |
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NCBI chr15:107,945,664...108,210,967
Ensembl chr15:107,945,664...108,210,826
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G |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of DRAM1 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 7:28,898,647...28,932,641
Ensembl chr 7:28,898,649...28,932,641
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G |
Drd5 |
dopamine receptor D5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DRD5 mRNA |
CTD |
PMID:19429434 |
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NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
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G |
Dusp2 |
dual specificity phosphatase 2 |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of DUSP2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
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NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
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G |
Dusp4 |
dual specificity phosphatase 4 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of DUSP4 mRNA |
CTD |
PMID:16497877 |
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NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
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G |
Dusp6 |
dual specificity phosphatase 6 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of DUSP6 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
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G |
Dync1li2 |
dynein, cytoplasmic 1 light intermediate chain 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of DYNC1LI2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr19:740,007...762,897
Ensembl chr19:740,028...762,897
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G |
Dynll1 |
dynein light chain LC8-type 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DYNLL1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
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G |
Dyrk2 |
dual specificity tyrosine phosphorylation regulated kinase 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of DYRK2 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 7:61,785,423...61,816,775
Ensembl chr 7:61,786,309...61,798,729
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G |
E2f2 |
E2F transcription factor 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of E2F2 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 5:154,516,611...154,540,228
Ensembl chr 5:154,522,119...154,540,265
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G |
Eci1 |
enoyl-CoA delta isomerase 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of ECI1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
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G |
Edn3 |
endothelin 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of EDN3 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
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G |
Ednra |
endothelin receptor type A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA |
CTD |
PMID:19059307 |
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NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
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G |
Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of EFEMP1 mRNA Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of EFEMP1 mRNA] |
CTD |
PMID:14699072 PMID:21185374 |
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NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
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G |
Efna1 |
ephrin A1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EFNA1 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases phosphorylation |
ISO EXP |
[Raloxifene Hydrochloride co-treated with epigallocatechin gallate] results in decreased phosphorylation of EGFR protein Raloxifene Hydrochloride results in increased phosphorylation of EGFR protein |
CTD |
PMID:18371987 PMID:24782323 |
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NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
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G |
Egln3 |
egl-9 family hypoxia-inducible factor 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of EGLN3 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
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G |
Egr1 |
early growth response 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
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G |
Egr3 |
early growth response 3 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of EGR3 mRNA] Raloxifene Hydrochloride results in decreased expression of EGR3 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
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NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EIF1 mRNA Raloxifene Hydrochloride results in increased expression of SUI1 mRNA |
CTD |
PMID:16497877 PMID:19059307 |
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NCBI chr10:88,227,455...88,229,546
Ensembl chr10:88,227,360...88,229,765
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF2S1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF5 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:136,002,983...136,011,409
Ensembl chr 6:136,004,214...136,011,406
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of EIF5A mRNA |
CTD |
PMID:16497877 |
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NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
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G |
Elf3 |
E74 like ETS transcription factor 3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA Raloxifene Hydrochloride results in increased expression of ELF3 mRNA |
CTD |
PMID:16202921 PMID:19059307 |
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NCBI chr13:52,083,873...52,088,798
Ensembl chr13:52,083,859...52,088,780
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G |
Ell |
elongation factor for RNA polymerase II |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ELL mRNA |
CTD |
PMID:15849065 |
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NCBI chr16:20,594,129...20,641,441
Ensembl chr16:20,594,072...20,641,908
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G |
Elob |
elongin B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ELOB mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:13,163,032...13,168,217
Ensembl chr10:13,163,036...13,168,217
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G |
Elovl5 |
ELOVL fatty acid elongase 5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ELOVL5 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
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G |
Emp1 |
epithelial membrane protein 1 |
multiple interactions |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EMP1 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
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G |
Enc1 |
ectodermal-neural cortex 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of ENC1 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
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G |
Endod1 |
endonuclease domain containing 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 8:12,898,430...12,928,156
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G |
Eng |
endoglin |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ENG mRNA; Raloxifene Hydrochloride results in increased expression of ENG protein |
CTD |
PMID:20135064 |
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NCBI chr 3:11,679,530...11,717,486
Ensembl chr 3:11,679,530...11,717,485
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G |
Eno2 |
enolase 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ENO2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 Ensembl chr 9:157,285,179...157,294,047
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ENPP2 mRNA Raloxifene Hydrochloride affects the expression of ENPP2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
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G |
Entpd2 |
ectonucleoside triphosphate diphosphohydrolase 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of ENTPD2 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
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G |
Epha1 |
Eph receptor A1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EPHA1 mRNA |
CTD |
PMID:12154049 |
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NCBI chr 4:71,749,100...71,763,681
Ensembl chr 4:71,749,242...71,763,679
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G |
Epha4 |
Eph receptor A4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of EPHA4 mRNA |
CTD |
PMID:26865669 |
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NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
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G |
Epor |
erythropoietin receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of EPOR mRNA |
CTD |
PMID:14699072 |
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NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
decreases response to substance |
ISO |
ERBB2 protein results in decreased susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:16609042 |
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NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
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G |
Erbb3 |
erb-b2 receptor tyrosine kinase 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ERBB3 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of ERBB4 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
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G |
Esr1 |
estrogen receptor 1 |
affects response to substance multiple interactions affects expression affects binding increases expression decreases expression decreases activity affects folding increases response to substance |
ISO EXP |
ESR1 gene polymorphism affects the susceptibility to Raloxifene Hydrochloride Raloxifene Hydrochloride binds to and affects the folding of ESR1 protein mutant form Raloxifene Hydrochloride affects the expression of ESR1 mRNA Raloxifene Hydrochloride metabolite binds to ESR1 protein ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA] Raloxifene Hydrochloride results in increased expression of ESR1 mRNA Raloxifene Hydrochloride results in decreased expression of ESR1 protein Raloxifene Hydrochloride results in decreased activity of ESR1 protein Raloxifene Hydrochloride binds to ESR1 protein [Raloxifene Hydrochloride binds to ESR1 protein] which binds to SERPINB9 protein; [Raloxifene Hydrochloride binds to ESR1 protein] which binds to TFF1 protein; Raloxifene Hydrochloride binds to ESR1 protein Raloxifene Hydrochloride affects the folding of ESR1 protein [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ANKRD28 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CCN3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of CSF2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of HAS2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of KCNN4 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LINC00312 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of PLAU mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of RGS16 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of SLN mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TGFBI mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TNFRSF11B mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of TXNIP mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of EIF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ENPP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of G0S2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of GRK5 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of IDH2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ISG20 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KLRC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of LPL mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PFKFB3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PTPRE mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RHOBTB3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RIPOR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SEMA3B mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SGK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of SYBU mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TIPARP mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TMOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of TMPRSS3 mRNA; [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ZNF395 mRNA; ARID5A protein inhibits the reaction [Raloxifene Hydrochloride results in increased activity of ESR1 protein]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EMP1 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of HSPA1B mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MFAP5 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of IDH2 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC2 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of PLPP3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of TGFB3 mRNA]; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of ZFP36 mRNA]; ESR1 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride affects the folding of and affects the activity of ESR1 protein; Raloxifene Hydrochloride binds to and affects the activity of ESR1 protein; Raloxifene Hydrochloride binds to and results in decreased activity of ESR1 protein; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to CCL3 promoter]; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to RELA protein]; Raloxifene Hydrochloride inhibits the reaction [Estradiol binds to ESR1 protein]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to PTGS2 promoter]; Raloxifene Hydrochloride results in increased activity of and affects the localization of ESR1 protein ESR1 exon polymorphism results in increased susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:9751507 PMID:11535548 PMID:11867264 PMID:14617632 PMID:14699072 PMID:15161930 PMID:15521089 PMID:15807179 PMID:15842231 PMID:15941852 PMID:15961563 PMID:16497877 PMID:16604479 PMID:16790557 PMID:16798746 PMID:17203231 PMID:17299137 PMID:17350824 PMID:17395694 PMID:17654759 PMID:17872375 PMID:18976723 PMID:19059307 PMID:19350480 PMID:19432593 PMID:20362049 PMID:20435135 PMID:21256200 PMID:21543282 PMID:24782323 PMID:25012808 PMID:26865669 PMID:27721470 |
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NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects expression increases activity decreases activity increases response to substance |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ABCC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACKR3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ACSL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AGO2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of AKAP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ARL4C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ASB13 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C2CD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CA12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CALM1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASKIN2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CASP7 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CCND1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CDK5R1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CEBPB mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CERS6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CLCN4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CRISPLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CSDC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CUEDC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP19A1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP24A1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of CYP26B1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of DOCK9 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EDNRA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ELF3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ENDOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAGEA8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PRKCZ mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGER3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGES mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RCOR3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RETREG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RFTN1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RGL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RHOF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RPS6KA2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SALL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SCNN1A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SEMA3F mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SERPINB6 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SLC18A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SREBF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SSH1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ST3GAL1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of STK24 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYBU mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNJ2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of SYNPO mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TACC2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TBXA2R mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TGFA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TMOD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TNS3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TOB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of TRAF3IP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of UPF1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of WNT5A mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZCCHC24 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZMIZ1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of ZNF395 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADAM19 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ADORA2B mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AMIGO2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ANKRD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of AREG mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ATF3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of BIRC3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CCL20 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDH2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CDO1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of CXCL8 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DACT1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DCBLD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of DUSP5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of EGR1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ENC1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTP4A3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTX3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RCAN2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RFK mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RRAD mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SLCO4C1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SOD2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TCIM mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFB2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TGFBI mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TMEM158 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNC mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF11B mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNFRSF21 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TNIK mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRAF5 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIB1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRIM36 mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of EDN3 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of METTL7A mRNA]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased activity of TERT protein]; Raloxifene Hydrochloride binds to and results in increased activity of ESR2 protein; Raloxifene Hydrochloride inhibits the reaction [3,3'-diindolylmethane results in increased expression of ESR2 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to PTGS2 promoter] Raloxifene Hydrochloride affects the expression of ESR2 mRNA ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; ESR2 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA] Raloxifene Hydrochloride binds to and affects the activity of ESR2 protein alternative form Raloxifene Hydrochloride results in increased activity of ESR2 protein Raloxifene Hydrochloride results in decreased activity of ESR2 protein ESR2 protein results in increased susceptibility to Raloxifene Hydrochloride |
CTD |
PMID:14699072 PMID:15924412 PMID:16798746 PMID:17638070 PMID:17654759 PMID:17872375 PMID:17962382 PMID:19059307 PMID:19350480 PMID:20160136 PMID:24782323 |
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NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
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G |
Evi2a |
ecotropic viral integration site 2A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of EVI2A mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:66,870,048...66,873,948
Ensembl chr10:66,870,067...66,873,948
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G |
F11 |
coagulation factor XI |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of F11 protein |
CTD |
PMID:16359964 |
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NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698
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G |
F12 |
coagulation factor XII |
increases activity |
ISO |
Raloxifene Hydrochloride results in increased activity of F12 protein |
CTD |
PMID:16359964 |
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NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
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G |
F13a1 |
coagulation factor XIII A1 chain |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of F13A1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr17:28,504,650...28,680,015
Ensembl chr17:28,504,623...28,680,362
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G |
F2r |
coagulation factor II (thrombin) receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of F2R mRNA |
CTD |
PMID:12154049 |
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NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
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G |
F8 |
coagulation factor VIII |
increases activity increases expression |
ISO |
Raloxifene Hydrochloride results in increased activity of F8 protein Raloxifene Hydrochloride results in increased expression of F8 protein |
CTD |
PMID:15850603 PMID:16359964 |
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NCBI chr18:367,862...399,242
Ensembl chr18:367,862...399,242
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of FABP4 mRNA |
CTD |
PMID:16643890 |
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NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
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G |
Fadd |
Fas associated via death domain |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FADD mRNA |
CTD |
PMID:19059307 |
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NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
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G |
Fam171b |
family with sequence similarity 171, member B |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of FAM171B mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 3:71,210,048...71,265,419
Ensembl chr 3:71,210,301...71,262,615
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G |
Fap |
fibroblast activation protein, alpha |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FAP mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:48,467,781...48,536,242
Ensembl chr 3:48,467,781...48,536,235
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|
G |
Fgd6 |
FYVE, RhoGEF and PH domain containing 6 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGD6 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929
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G |
Fgf8 |
fibroblast growth factor 8 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of FGF8 mRNA |
CTD |
PMID:29990529 |
|
NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
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G |
Fgf9 |
fibroblast growth factor 9 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of FGF9 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
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|
G |
Fgfr2 |
fibroblast growth factor receptor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FGFR2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
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G |
Fhl1 |
four and a half LIM domains 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of FHL1 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr X:159,112,516...159,172,528
Ensembl chr X:159,112,880...159,172,524
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G |
Fhl2 |
four and a half LIM domains 2 |
multiple interactions decreases expression affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of FHL2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FHL2 mRNA Raloxifene Hydrochloride results in decreased expression of FHL2 mRNA Raloxifene Hydrochloride affects the expression of FHL2 mRNA |
CTD |
PMID:14699072 PMID:19059307 PMID:26865669 |
|
NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
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G |
Fis1 |
fission, mitochondrial 1 |
affects expression increases expression |
EXP |
Raloxifene Hydrochloride affects the expression of FIS1 mRNA Raloxifene Hydrochloride results in increased expression of FIS1 mRNA |
CTD |
PMID:15576828 PMID:16079270 |
|
NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
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G |
Fkbp3 |
FKBP prolyl isomerase 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of FKBP3 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 6:86,810,865...86,822,115
Ensembl chr 6:86,810,809...86,822,094
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G |
Flnb |
filamin B |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FLNB mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FLNB mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of FLNB mRNA] |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr15:18,750,152...18,883,019
Ensembl chr15:18,750,118...18,883,005
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G |
Flnc |
filamin C |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FLNC mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
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G |
Flrt1 |
fibronectin leucine rich transmembrane protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FLRT1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:222,340,481...222,417,915
Ensembl chr 1:222,344,713...222,350,173
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G |
Fmnl1 |
formin-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FMNL1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr10:91,253,757...91,281,422
Ensembl chr10:91,254,058...91,281,418
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|
G |
Fn1 |
fibronectin 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [TGFB1 protein results in increased expression of FN1 mRNA] |
CTD |
PMID:15920148 |
|
NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
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|
G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOSL2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
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G |
Foxa2 |
forkhead box A2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of FOXA2 mRNA |
CTD |
PMID:23184660 |
|
NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
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G |
Foxc1 |
forkhead box C1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FOXC1 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr17:33,947,501...33,951,484
Ensembl chr17:33,947,506...33,951,484
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G |
Foxe1 |
forkhead box E1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of FOXE1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 5:61,954,549...61,957,357
Ensembl chr 5:61,954,549...61,957,357
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G |
Foxo1 |
forkhead box O1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FOXO1 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FOXO1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
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G |
Fst |
follistatin |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of FST mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of FST mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
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G |
Fut9 |
fucosyltransferase 9 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of FUT9 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 5:40,032,855...40,237,591
Ensembl chr 5:40,032,855...40,237,591
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G |
Fyttd1 |
forty-two-three domain containing 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of FYTTD1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr11:71,113,931...71,136,694
Ensembl chr11:71,116,579...71,136,673
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G |
Fzd6 |
frizzled class receptor 6 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of FZD6 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
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G |
G0s2 |
G0/G1switch 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of G0S2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
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G |
Gabarap |
GABA type A receptor-associated protein |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GABARAP mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:56,601,288...56,604,223
Ensembl chr10:56,601,288...56,604,221
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G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of GABBR2 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
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G |
Gabpa |
GA binding protein transcription factor subunit alpha |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GABPA mRNA |
CTD |
PMID:12154049 |
|
NCBI chr11:24,293,845...24,322,822
Ensembl chr11:24,263,281...24,322,815
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G |
Gabrg1 |
gamma-aminobutyric acid type A receptor subunit gamma 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GABRG1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr14:39,964,502...40,051,306
Ensembl chr14:39,964,588...40,049,354
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G |
Gabrr1 |
gamma-aminobutyric acid type A receptor subunit rho 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GABRR1 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of GABRR1 mRNA] |
CTD |
PMID:14699072 |
|
NCBI chr 5:48,374,048...48,411,170
Ensembl chr 5:48,374,096...48,411,170
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G |
Gad1 |
glutamate decarboxylase 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GAD1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
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G |
Gal |
galanin and GMAP prepropeptide |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GAL mRNA |
CTD |
PMID:16202921 |
|
NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
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G |
Gas6 |
growth arrest specific 6 |
increases expression affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of GAS6 mRNA Raloxifene Hydrochloride affects the expression of GAS6 mRNA fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of GAS6 mRNA] |
CTD |
PMID:16079270 PMID:19429434 |
|
NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
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G |
Gata2 |
GATA binding protein 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GATA2 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
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|
G |
Gcnt1 |
glucosaminyl (N-acetyl) transferase 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GCNT1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:236,547,729...236,585,037
Ensembl chr 1:236,580,034...236,585,035
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G |
Gdf9 |
growth differentiation factor 9 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GDF9 mRNA |
CTD |
PMID:22841776 |
|
NCBI chr10:38,782,519...38,793,238
Ensembl chr10:38,788,992...38,792,940
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G |
Gfra2 |
GDNF family receptor alpha 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of GFRA2 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr15:52,557,004...52,648,984
Ensembl chr15:52,557,607...52,648,972
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G |
Gh1 |
growth hormone 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] |
CTD |
PMID:17272397 |
|
NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
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G |
Ghr |
growth hormone receptor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GHR mRNA |
CTD |
PMID:16202921 |
|
NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
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G |
Ghrh |
growth hormone releasing hormone |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GHRH mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 3:153,449,124...153,468,794
Ensembl chr 3:153,449,125...153,468,794
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G |
Ghrhr |
growth hormone releasing hormone receptor |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GHRHR mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 4:85,587,321...85,602,389
Ensembl chr 4:85,588,595...85,601,666
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G |
Gjb2 |
gap junction protein, beta 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GJB2 mRNA |
CTD |
PMID:12370124 |
|
NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
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G |
Glrb |
glycine receptor, beta |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLRB mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:179,768,040...179,842,612
Ensembl chr 2:179,769,009...179,842,547
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G |
Glrx |
glutaredoxin |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLRX mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
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G |
Glul |
glutamate-ammonia ligase |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GLUL mRNA |
CTD |
PMID:16079270 |
|
NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
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G |
Glyat |
glycine-N-acyltransferase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GLYAT mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:229,060,125...229,081,113
Ensembl chr 1:229,063,714...229,080,410
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G |
Gnb1 |
G protein subunit beta 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GNB1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
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G |
Gnb4 |
G protein subunit beta 4 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of GNB4 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 2:118,978,965...119,007,877
Ensembl chr 2:118,978,973...119,007,835
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|
G |
Gnrh1 |
gonadotropin releasing hormone 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol promotes the reaction [GNRH1 protein results in increased secretion of PRL protein]] |
CTD |
PMID:17054466 |
|
NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875 Ensembl chr15:44,442,555...44,442,875
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G |
Golga5 |
golgin A5 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GOLGA5 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 6:126,350,572...126,378,735
Ensembl chr 6:126,353,223...126,378,610
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G |
Gpc1 |
glypican 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of GPC1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 9:99,998,275...100,026,818
Ensembl chr 9:99,998,275...100,026,818
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G |
Gpc3 |
glypican 3 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of GPC3 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr X:139,579,268...139,947,093
Ensembl chr X:139,579,268...139,916,883
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G |
Gper1 |
G protein-coupled estrogen receptor 1 |
multiple interactions increases activity |
EXP |
[4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline binds to and results in decreased activity of GPER1 protein] inhibits the reaction [[Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; [4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline results in decreased activity of GPER1 protein] inhibits the reaction [[Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A3 protein]; [Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein; [Raloxifene Hydrochloride results in increased activity of GPER1 protein] which results in increased expression of SLC1A3 protein |
CTD |
PMID:24782323 |
|
NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
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G |
Gpnmb |
glycoprotein nmb |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of GPNMB mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
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G |
Gprc5c |
G protein-coupled receptor, class C, group 5, member C |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of GPRC5C mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:103,395,222...103,417,360
Ensembl chr10:103,395,511...103,417,358
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G |
Grb10 |
growth factor receptor bound protein 10 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GRB10 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GRB10 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr14:92,021,851...92,122,249
Ensembl chr14:92,021,851...92,117,923
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G |
Greb1 |
growth regulating estrogen receptor binding 1 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of GREB1 mRNA] Raloxifene Hydrochloride results in decreased expression of GREB1 mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 6:41,932,941...42,002,770
Ensembl chr 6:41,932,244...42,002,819
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G |
Grhl1 |
grainyhead-like transcription factor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of GRHL1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 6:43,734,837...43,795,757
Ensembl chr 6:43,743,702...43,794,342
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G |
Grina |
glutamate ionotropic receptor NMDA type subunit associated protein 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of GRINA mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916
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G |
Grk5 |
G protein-coupled receptor kinase 5 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of GRK5 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of GRK5 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 1:282,265,371...282,467,842
Ensembl chr 1:282,265,370...282,462,605
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G |
Gyg1 |
glycogenin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of GYG1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 2:104,916,734...104,958,219
Ensembl chr 2:104,916,738...104,958,034
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G |
Hal |
histidine ammonia lyase |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HAL mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
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|
G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HAPLN1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:18,354,542...18,419,077
Ensembl chr 2:18,354,542...18,419,071
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|
G |
Has2 |
hyaluronan synthase 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of HAS2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
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G |
Hba-a1 |
hemoglobin alpha, adult chain 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HBA-A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649
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|
G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of HBEGF mRNA |
CTD |
PMID:19059307 |
|
NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
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|
G |
Hbg1 |
hemoglobin subunit gamma 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HBG1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:168,992,841...168,994,219
Ensembl chr 1:168,992,722...168,994,253
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G |
Hbp1 |
HMG-box transcription factor 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of HBP1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr 6:51,231,479...51,257,699
Ensembl chr 6:51,231,480...51,257,625
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G |
Heg1 |
heart development protein with EGF-like domains 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of HEG1 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HEG1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HEG1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr11:70,234,248...70,322,966
Ensembl chr11:70,236,888...70,322,690
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G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of HERPUD1 mRNA |
CTD |
PMID:16497877 |
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NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
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G |
Hey2 |
hes-related family bHLH transcription factor with YRPW motif 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HEY2 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
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G |
Hgf |
hepatocyte growth factor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HGF mRNA |
CTD |
PMID:16497877 |
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NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
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G |
Hk1 |
hexokinase 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of HK1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HK1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
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G |
Hmcn1 |
hemicentin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of HMCN1 mRNA |
CTD |
PMID:21185374 |
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NCBI chr13:67,799,791...68,360,664
Ensembl chr13:67,799,791...68,360,664
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G |
Hmga2 |
high mobility group AT-hook 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HMGA2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
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G |
Hmgb1 |
high mobility group box 1 |
decreases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of HMGB1 mRNA Raloxifene Hydrochloride affects the expression of HMGB1 mRNA |
CTD |
PMID:16079270 PMID:16514628 |
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NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions affects expression decreases expression increases expression |
ISO EXP |
1,10-phenanthroline inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HMOX1 mRNA; Allopurinol inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Buthionine Sulfoximine promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Copper promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; dimethyl sulfate inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; Glutathione inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; HMOX1 protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]; Iron promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA]; MAP2K6 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 protein]; TEMPO inhibits the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA] Raloxifene Hydrochloride affects the expression of HMOX1 mRNA Raloxifene Hydrochloride results in decreased expression of HMOX1 mRNA Raloxifene Hydrochloride results in increased expression of HMOX1 mRNA; Raloxifene Hydrochloride results in increased expression of HMOX1 protein |
CTD |
PMID:16079270 PMID:16298037 PMID:19059307 PMID:20888885 |
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NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
decreases expression multiple interactions |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in decreased expression of HNF4A mRNA] |
CTD |
PMID:23184660 |
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NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPA2B1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
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G |
Hnrnph1 |
heterogeneous nuclear ribonucleoprotein H1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPH1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:35,872,619...35,879,911
Ensembl chr10:35,870,232...35,879,910
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G |
Hnrnpu |
heterogeneous nuclear ribonucleoprotein U |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HNRNPU mRNA |
CTD |
PMID:16514628 |
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NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
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G |
Homer2 |
homer scaffold protein 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of HOMER2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583
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G |
Hoxa1 |
homeobox A1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HOXA1 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 4:82,124,358...82,127,182
Ensembl chr 4:82,125,406...82,127,066
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G |
Hpcal1 |
hippocalcin-like 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HPCAL1 mRNA |
CTD |
PMID:19059307 |
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NCBI chr 6:43,001,920...43,109,083
Ensembl chr 6:43,001,948...43,109,071
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HPGD mRNA] |
CTD |
PMID:21185374 |
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NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
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G |
Hsd17b11 |
hydroxysteroid (17-beta) dehydrogenase 11 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of HSD17B11 mRNA |
CTD |
PMID:21185374 |
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NCBI chr14:7,054,724...7,104,567
Ensembl chr14:7,073,445...7,104,566
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G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HSD17B4 mRNA |
CTD |
PMID:16079270 |
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NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
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G |
Hsp90ab1 |
heat shock protein 90 alpha family class B member 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSP90AB1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSP90B1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
affects expression increases expression |
ISO EXP |
Raloxifene Hydrochloride affects the expression of HSPA1A mRNA Raloxifene Hydrochloride results in increased expression of HSPA1A protein |
CTD |
PMID:14699072 PMID:15860553 |
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NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
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G |
Hspa1b |
heat shock protein family A (Hsp70) member 1B |
multiple interactions affects expression |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of HSPA1B mRNA] Raloxifene Hydrochloride affects the expression of HSPA1B mRNA |
CTD |
PMID:14699072 |
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NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
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G |
Hspa4 |
heat shock protein family A (Hsp70) member 4 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSPA4 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of HSPA8 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
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G |
Hspb8 |
heat shock protein family B (small) member 8 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HSPB8 mRNA; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of HSPB8 mRNA] |
CTD |
PMID:19059307 PMID:21185374 |
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NCBI chr12:45,905,371...45,920,014
Ensembl chr12:45,905,371...45,920,013
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of HSPD1 mRNA Raloxifene Hydrochloride affects the expression of HSPD1 mRNA |
CTD |
PMID:16079270 PMID:16514628 |
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NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
affects expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride affects the expression of HTR2A mRNA Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A mRNA]; Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased expression of HTR2A protein] |
CTD |
PMID:14699072 PMID:17398000 |
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NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
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G |
Htr3a |
5-hydroxytryptamine receptor 3A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of HTR3A mRNA |
CTD |
PMID:19059307 |
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NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
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G |
Htr5a |
5-hydroxytryptamine receptor 5A |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of HTR5A mRNA |
CTD |
PMID:16079270 |
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NCBI chr 4:199,916...209,599
Ensembl chr 4:199,916...209,599
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G |
Id1 |
inhibitor of DNA binding 1, HLH protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ID1 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
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G |
Id4 |
inhibitor of DNA binding 4, HLH protein |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of ID4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr17:16,692,557...16,695,126
Ensembl chr17:16,692,557...16,695,126
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions affects expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of IDH2 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of IDH2 mRNA] Raloxifene Hydrochloride affects the expression of IDH2 mRNA |
CTD |
PMID:14699072 PMID:16079270 PMID:19059307 |
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NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
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G |
Ido1 |
indoleamine 2,3-dioxygenase 1 |
multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of IDO1 mRNA] Raloxifene Hydrochloride results in increased expression of IDO1 mRNA |
CTD |
PMID:18367319 |
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NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
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G |
Ier3 |
immediate early response 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of IER3 mRNA ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of IER3 mRNA] |
CTD |
PMID:14699072 |
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NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
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G |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IFIT2 mRNA |
CTD |
PMID:14699072 |
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NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
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G |
Ifngr2 |
interferon gamma receptor 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of IFNGR2 mRNA |
CTD |
PMID:19059307 |
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NCBI chr11:31,694,339...31,712,611
Ensembl chr11:31,694,339...31,712,611
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G |
Ifrd1 |
interferon-related developmental regulator 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IFRD1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions affects expression increases expression decreases expression |
ISO EXP |
Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA1 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to IGF1 promoter] Raloxifene Hydrochloride affects the expression of IGF1 mRNA Raloxifene Hydrochloride results in increased expression of IGF1 mRNA Raloxifene Hydrochloride results in decreased expression of IGF1 mRNA; Raloxifene Hydrochloride results in decreased expression of IGF1 protein |
CTD |
PMID:15762036 PMID:15978972 PMID:16912660 PMID:17645796 PMID:17872375 PMID:19350480 |
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NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
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G |
Igf2 |
insulin-like growth factor 2 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of IGF2 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IGFBP3 protein |
CTD |
PMID:15855258 PMID:16912660 |
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NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IGFBP4 mRNA |
CTD |
PMID:14699072 |
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NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
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G |
Igfbp6 |
insulin-like growth factor binding protein 6 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of IGFBP6 mRNA |
CTD |
PMID:15576828 |
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NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
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G |
Il10ra |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of IL10RA mRNA |
CTD |
PMID:16497877 |
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NCBI chr 8:49,558,062...49,573,891
Ensembl chr 8:49,560,035...49,573,742
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G |
Il12a |
interleukin 12A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IL12A mRNA |
CTD |
PMID:19429434 |
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NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with IL1B protein] results in increased expression of PTGDS mRNA; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of BCL3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CISH mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of CXCL5 mRNA]; Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA] |
CTD |
PMID:12072388 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il1r1 |
interleukin 1 receptor type 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of IL1R1 mRNA] |
CTD |
PMID:21185374 |
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NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
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G |
Il1rap |
interleukin 1 receptor accessory protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL1RAP mRNA |
CTD |
PMID:14699072 |
|
NCBI chr11:77,456,648...77,593,208
Ensembl chr11:77,463,954...77,593,207
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G |
Il4r |
interleukin 4 receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL4R mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
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G |
Il6 |
interleukin 6 |
decreases expression multiple interactions |
ISO EXP |
Raloxifene Hydrochloride results in decreased expression of IL6 mRNA; Raloxifene Hydrochloride results in decreased expression of IL6 protein Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 mRNA]; Raloxifene Hydrochloride inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL6 protein]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] |
CTD |
PMID:15579764 PMID:15762036 PMID:15953991 PMID:16298037 PMID:19533603 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Il7r |
interleukin 7 receptor |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of IL7R mRNA |
CTD |
PMID:14699072 |
|
|
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G |
Ilrun |
inflammation and lipid regulator with UBA-like and NBR1-like domains |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of ILRUN mRNA |
CTD |
PMID:16514628 |
|
NCBI chr20:7,331,321...7,397,588
Ensembl chr20:7,331,326...7,397,448
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G |
Inhba |
inhibin subunit beta A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of INHBA mRNA |
CTD |
PMID:19059307 |
|
NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
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G |
Inpp4b |
inositol polyphosphate-4-phosphatase type II B |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of INPP4B mRNA |
CTD |
PMID:14699072 |
|
NCBI chr19:29,592,889...30,341,528
Ensembl chr19:29,597,905...29,968,424
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G |
Inpp5a |
inositol polyphosphate-5-phosphatase A |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of INPP5A mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:211,732,163...211,920,844
Ensembl chr 1:211,732,713...211,921,099
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G |
Insig1 |
insulin induced gene 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of INSIG1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
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G |
Iqgap1 |
IQ motif containing GTPase activating protein 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of IQGAP1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 1:142,525,041...142,615,673
Ensembl chr 1:142,525,046...142,615,673
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G |
Irf7 |
interferon regulatory factor 7 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of IRF7 mRNA |
CTD |
PMID:16079270 |
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NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
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G |
Isg20 |
interferon stimulated exonuclease gene 20 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of ISG20 mRNA Raloxifene Hydrochloride affects the expression of ISG20 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946
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G |
Itgb1 |
integrin subunit beta 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of ITGB1 mRNA |
CTD |
PMID:12154049 PMID:19429434 |
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NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
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G |
Itpr3 |
inositol 1,4,5-trisphosphate receptor, type 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of ITPR3 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr20:5,645,894...5,711,702
Ensembl chr20:5,646,097...5,711,702
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G |
Ivl |
involucrin |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of IVL mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of IVL mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
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G |
Jag1 |
jagged canonical Notch ligand 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of JAG1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
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G |
Jak2 |
Janus kinase 2 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] Raloxifene Hydrochloride results in decreased expression of JAK2 mRNA |
CTD |
PMID:17272397 PMID:26865669 |
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NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
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Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of JUN mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
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G |
Kazn |
kazrin, periplakin interacting protein |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KAZN mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 5:160,637,235...161,730,513
Ensembl chr 5:160,639,578...160,742,479
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G |
Kcne1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of KCNE1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
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G |
Kcnh5 |
potassium voltage-gated channel subfamily H member 5 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of KCNH5 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 6:97,872,831...98,157,087
Ensembl chr 6:97,872,831...98,157,087
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G |
Kcnn4 |
potassium calcium-activated channel subfamily N member 4 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of KCNN4 mRNA Raloxifene Hydrochloride affects the expression of KCNN4 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
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G |
Kctd12 |
potassium channel tetramerization domain containing 12 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KCTD12 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KCTD12 mRNA Raloxifene Hydrochloride affects the expression of KCTD12 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr15:87,384,632...87,390,627
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G |
Kif20a |
kinesin family member 20A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KIF20A mRNA |
CTD |
PMID:16514628 |
|
NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
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G |
Kif3c |
kinesin family member 3C |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KIF3C mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:27,768,943...27,815,611
Ensembl chr 6:27,768,943...27,815,611
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G |
Kiss1 |
KiSS-1 metastasis-suppressor |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of KISS1 mRNA |
CTD |
PMID:27395752 |
|
NCBI chr13:50,529,506...50,537,603
Ensembl chr13:50,529,510...50,535,389
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G |
Klf10 |
Kruppel-like factor 10 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of KLF10 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:77,156,010...77,162,096
Ensembl chr 7:77,156,006...77,162,148
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G |
Klf6 |
Kruppel-like factor 6 |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of KLF6 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
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G |
Klhl24 |
kelch-like family member 24 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of KLHL24 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr11:84,613,101...84,643,674
Ensembl chr11:84,615,760...84,633,504
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G |
Klrc1 |
killer cell lectin like receptor C1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of KLRC1 mRNA |
CTD |
PMID:17962382 |
|
NCBI chr 4:163,453,435...163,463,718
Ensembl chr 4:163,458,528...163,463,718
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G |
Klrc2 |
killer cell lectin like receptor C2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of KLRC2 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of KLRC2 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC2 mRNA]; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of KLRC2 mRNA] |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 4:163,433,993...163,445,136
Ensembl chr 4:163,416,351...163,445,302
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G |
Klrc3 |
killer cell lectin like receptor C3 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRC3 mRNA; ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of KLRC3 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of KLRC3 mRNA]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to KLRC3 gene] |
CTD |
PMID:17395694 PMID:19059307 |
|
NCBI chr 4:163,416,373...163,427,331
Ensembl chr 4:163,416,351...163,445,302
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G |
Klrk1 |
killer cell lectin like receptor K1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of KLRK1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 4:163,392,652...163,403,735
Ensembl chr 4:163,393,217...163,403,653
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G |
Kpna2 |
karyopherin subunit alpha 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KPNA2 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr10:95,200,029...95,212,111
Ensembl chr10:95,200,030...95,212,111
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G |
Kpnb1 |
karyopherin subunit beta 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of KPNB1 mRNA |
CTD |
PMID:16514628 |
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NCBI chr10:85,096,517...85,124,641
Ensembl chr10:85,093,841...85,124,644
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G |
Krt17 |
keratin 17 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT17 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:88,158,993...88,163,712
Ensembl chr10:88,118,001...88,163,723
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G |
Krt34 |
keratin 34 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of KRT34 mRNA |
CTD |
PMID:19059307 |
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NCBI chr10:87,950,364...87,954,055
Ensembl chr10:87,950,001...87,954,055
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G |
L3mbtl1 |
L3MBTL histone methyl-lysine binding protein 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of L3MBTL1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 3:159,316,580...159,348,914
Ensembl chr 3:159,321,310...159,347,631
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G |
Lamc1 |
laminin subunit gamma 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LAMC1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
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G |
Lbh |
LBH regulator of WNT signaling pathway |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LBH mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:24,154,207...24,184,217
Ensembl chr 6:24,160,226...24,181,866
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G |
Lcn2 |
lipocalin 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LCN2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
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G |
Ldlr |
low density lipoprotein receptor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of LDLR mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
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G |
Ldlrad4 |
low density lipoprotein receptor class A domain containing 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LDLRAD4 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr18:63,717,423...64,045,224
Ensembl chr18:63,882,610...64,044,023
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G |
Lepr |
leptin receptor |
affects expression |
EXP |
Raloxifene decreases Lepr protein expression in adipose tissue at 7 weeks and increases it at 22 weeks |
RGD |
PMID:15059958 |
RGD:1581837 |
NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
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G |
Lhb |
luteinizing hormone subunit beta |
multiple interactions decreases secretion |
EXP |
Raloxifene Hydrochloride inhibits the reaction [estradiol 3-benzoate results in increased secretion of LHB protein] Raloxifene Hydrochloride results in decreased secretion of LHB protein |
CTD |
PMID:17398000 PMID:27395752 |
|
NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
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G |
Limch1 |
LIM and calponin homology domains 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of LIMCH1 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr14:42,760,363...43,072,976
Ensembl chr14:42,762,587...43,072,843
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G |
Liph |
lipase H |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of LIPH mRNA |
CTD |
PMID:21185374 |
|
NCBI chr11:82,680,167...82,732,145
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G |
Lmcd1 |
LIM and cysteine-rich domains 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of LMCD1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of LMCD1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 4:144,192,989...144,252,554
Ensembl chr 4:144,192,989...144,252,551
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G |
Lmnb2 |
lamin B2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of LMNB2 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LMNB2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 7:11,657,870...11,676,936
Ensembl chr 7:11,660,934...11,675,472
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G |
LOC100909954 |
uncharacterized LOC100909954 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of C14ORF132 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of C14ORF132 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 6:129,259,581...129,322,113
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G |
LOC299277 |
similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of SERPINA3 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 6:127,871,895...127,888,287
Ensembl chr 6:127,872,666...127,886,540
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G |
Lox |
lysyl oxidase |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of LOX mRNA |
CTD |
PMID:16079270 |
|
NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
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G |
Lpl |
lipoprotein lipase |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of LPL mRNA Raloxifene Hydrochloride results in increased expression of LPL mRNA |
CTD |
PMID:16643890 PMID:19059307 |
|
NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
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G |
Lrig1 |
leucine-rich repeats and immunoglobulin-like domains 1 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRIG1 mRNA Raloxifene Hydrochloride affects the expression of LRIG1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 4:126,615,998...126,717,434
Ensembl chr 4:126,617,244...126,644,895
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G |
Lrrc20 |
leucine rich repeat containing 20 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LRRC20 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr20:31,069,406...31,202,502
Ensembl chr20:31,096,214...31,202,514
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G |
Ltb |
lymphotoxin beta |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of LTB mRNA |
CTD |
PMID:19429434 |
|
NCBI chr20:5,184,631...5,186,476
Ensembl chr20:5,184,515...5,186,503 Ensembl chr20:5,184,515...5,186,503
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G |
Ltbp1 |
latent transforming growth factor beta binding protein 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LTBP1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 6:21,203,502...21,600,441
Ensembl chr 6:21,203,502...21,600,451
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G |
Lum |
lumican |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of LUM mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:38,820,058...38,826,862
Ensembl chr 7:38,819,771...38,826,862
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G |
Lyn |
LYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of LYN mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
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G |
Lysmd4 |
LysM domain containing 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of LYSMD4 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:128,199,100...128,204,989
Ensembl chr 1:128,199,322...128,203,268
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G |
Macroh2a1 |
macroH2A.1 histone |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of MACROH2A1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr17:9,282,109...9,344,698
Ensembl chr17:9,282,675...9,344,678
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G |
Maf |
MAF bZIP transcription factor |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MAF mRNA |
CTD |
PMID:19429434 |
|
NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748
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G |
Maff |
MAF bZIP transcription factor F |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAFF mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
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G |
Man2a2 |
mannosidase, alpha, class 2A, member 2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MAN2A2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:142,141,695...142,164,561
Ensembl chr 1:142,143,799...142,164,263
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G |
Map2k3 |
mitogen activated protein kinase kinase 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of MAP2K3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753 Ensembl chr10:47,182,433...47,203,753
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
multiple interactions |
ISO |
MAP2K6 protein promotes the reaction [Raloxifene Hydrochloride results in increased expression of HMOX1 protein] |
CTD |
PMID:20888885 |
|
NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
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G |
Map3k11 |
mitogen-activated protein kinase kinase kinase 11 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MAP3K11 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 1:221,043,119...221,056,420
Ensembl chr 1:221,043,119...221,056,417
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G |
Map3k20 |
mitogen-activated protein kinase kinase kinase 20 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MAP3K20 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 3:58,965,025...59,120,507
Ensembl chr 3:58,965,552...59,067,369
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K5 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
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G |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAP3K8 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO EXP |
U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK1 protein] Raloxifene Hydrochloride inhibits the reaction [Methylmercury Compounds results in increased activity of MAPK1 protein] |
CTD |
PMID:15712295 PMID:16798746 PMID:17174166 PMID:20945400 PMID:24782323 |
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NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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G |
Mapk14 |
mitogen activated protein kinase 14 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of MAPK14 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
Raloxifene Hydrochloride inhibits the reaction [Methylmercury Compounds results in increased activity of MAPK3 protein] Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein U 0126 inhibits the reaction [Raloxifene Hydrochloride results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:15712295 PMID:16798746 PMID:17174166 PMID:20945400 PMID:24782323 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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G |
Mapkapk2 |
MAPK activated protein kinase 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MAPKAPK2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
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G |
Marcksl1 |
MARCKS-like 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MARCKSL1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 5:147,714,163...147,716,486
Ensembl chr 5:147,714,163...147,716,485
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G |
Matr3 |
matrin 3 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MATR3 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr18:28,351,691...28,390,764
Ensembl chr18:28,361,283...28,390,717
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G |
Mbnl2 |
muscleblind-like splicing regulator 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MBNL2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr15:105,640,097...105,797,933
Ensembl chr15:105,640,097...105,797,932
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G |
Mctp1 |
multiple C2 and transmembrane domain containing 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MCTP1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 2:3,400,883...4,089,949
Ensembl chr 2:3,400,977...4,088,989
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G |
Mdfic |
MyoD family inhibitor domain containing |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of MDFIC mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MDFIC mRNA |
CTD |
PMID:14699072 PMID:19059307 |
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NCBI chr 4:42,202,546...42,282,499
Ensembl chr 4:42,202,838...42,282,496
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G |
Mef2a |
myocyte enhancer factor 2a |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MEF2A mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:128,207,715...128,341,681
Ensembl chr 1:128,209,971...128,341,263
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G |
Mettl7a |
methyltransferase like 7A |
multiple interactions affects expression |
ISO |
ESR2 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of METTL7A mRNA] Raloxifene Hydrochloride affects the expression of METTL7A mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:141,973,447...142,021,344
Ensembl chr 7:141,973,553...141,981,432
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G |
Mfap5 |
microfibril associated protein 5 |
multiple interactions affects expression |
ISO |
ESR1 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MFAP5 mRNA] Raloxifene Hydrochloride affects the expression of MFAP5 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 4:155,313,671...155,336,228
Ensembl chr 4:155,313,671...155,336,228
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G |
Mgp |
matrix Gla protein |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of MGP mRNA] Raloxifene Hydrochloride results in decreased expression of MGP mRNA |
CTD |
PMID:16514628 PMID:21185374 |
|
NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
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G |
Mical2 |
microtubule associated monooxygenase, calponin and LIM domain containing 2 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MICAL2 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 1:177,048,607...177,173,729
Ensembl chr 1:177,048,655...177,173,995
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G |
Mid1 |
midline 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of MID1 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr X:25,458,782...25,839,941
Ensembl chr X:25,458,771...25,628,272
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G |
Mki67 |
marker of proliferation Ki-67 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MKI67 protein |
CTD |
PMID:11535548 |
|
NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
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G |
Mmd2 |
monocyte to macrophage differentiation-associated 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MMD2 mRNA |
CTD |
PMID:22841776 |
|
NCBI chr12:14,021,724...14,078,121
Ensembl chr12:14,021,727...14,078,134
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G |
Mmp12 |
matrix metallopeptidase 12 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of MMP12 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MMP12 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
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G |
Mmp2 |
matrix metallopeptidase 2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of MMP2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
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G |
Mmp9 |
matrix metallopeptidase 9 |
decreases activity multiple interactions increases expression decreases expression |
ISO EXP |
Raloxifene Hydrochloride results in decreased activity of MMP9 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride co-treated with Fluoxetine] affects the expression of MMP9 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Raloxifene Hydrochloride] affects the expression of MMP9 protein Raloxifene Hydrochloride results in increased expression of MMP9 mRNA Raloxifene Hydrochloride results in decreased expression of MMP9 mRNA |
CTD |
PMID:17582780 PMID:22841776 PMID:31332895 |
|
NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
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G |
Mn1 |
MN1 proto-oncogene, transcriptional regulator |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MN1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr12:51,214,192...51,250,230
Ensembl chr12:51,214,192...51,250,230
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G |
Mpo |
myeloperoxidase |
multiple interactions |
EXP |
Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased activity of MPO protein] |
CTD |
PMID:15860553 |
|
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
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G |
Mpped2 |
metallophosphoesterase domain containing 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MPPED2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 3:97,720,308...97,899,735
Ensembl chr 3:97,721,668...97,896,422
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G |
Mr1 |
major histocompatibility complex, class I-related |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MR1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
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G |
Mrpl33 |
mitochondrial ribosomal protein L33 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MRPL33 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 6:26,130,278...26,138,498
Ensembl chr 6:26,130,488...26,138,414
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G |
Msmb |
microseminoprotein, beta |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of MSMB mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of MSMB mRNA] Raloxifene Hydrochloride affects the expression of MSMB mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr16:8,280,275...8,300,853
Ensembl chr16:8,280,275...8,300,852
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G |
Mst1 |
macrophage stimulating 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MST1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
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G |
Mt2A |
metallothionein 2A |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of MT2A mRNA |
CTD |
PMID:20945400 |
|
NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
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G |
Mthfr |
methylenetetrahydrofolate reductase |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MTHFR mRNA |
CTD |
PMID:15849065 |
|
NCBI chr 5:164,844,642...164,864,360
Ensembl chr 5:164,845,925...164,860,910
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G |
Muc1 |
mucin 1, cell surface associated |
increases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of MUC1 protein Raloxifene Hydrochloride affects the expression of MUC1 mRNA |
CTD |
PMID:16012748 PMID:16079270 |
|
NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
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G |
Myb |
MYB proto-oncogene, transcription factor |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of MYB mRNA] Raloxifene Hydrochloride results in decreased expression of MYB mRNA |
CTD |
PMID:21185374 PMID:26865669 |
|
NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817
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G |
Mybl1 |
MYB proto-oncogene like 1 |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in decreased expression of MYBL1 mRNA Raloxifene Hydrochloride results in decreased expression of MYBL1 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
|
NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein] Raloxifene Hydrochloride results in decreased expression of MYC mRNA; Raloxifene Hydrochloride results in decreased expression of MYC protein |
CTD |
PMID:16497877 PMID:20945400 PMID:26502914 |
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NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
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G |
Myl9 |
myosin light chain 9 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of MYL9 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
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G |
Myo10 |
myosin X |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of MYO10 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 2:77,868,398...78,072,443
Ensembl chr 2:77,868,412...78,071,309
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G |
Myod1 |
myogenic differentiation 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of MYOD1 mRNA |
CTD |
PMID:19432593 |
|
NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
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G |
Myt1l |
myelin transcription factor 1-like |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of MYT1L mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:48,452,385...48,843,443
Ensembl chr 6:48,452,369...48,857,936
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G |
Nab1 |
Ngfi-A binding protein 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NAB1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 9:53,906,073...53,945,474
Ensembl chr 9:53,906,073...53,945,473
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G |
Nars1 |
asparaginyl-tRNA synthetase 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NARS1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr18:59,986,350...60,002,644
Ensembl chr18:59,986,360...60,002,569
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G |
Nav2 |
neuron navigator 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NAV2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 1:104,575,765...104,941,554
Ensembl chr 1:104,576,589...104,941,552
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G |
Nbl1 |
NBL1, DAN family BMP antagonist |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of NBL1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr 5:157,524,569...157,535,701
Ensembl chr 5:157,524,513...157,535,664
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G |
Ncaph |
non-SMC condensin I complex, subunit H |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NCAPH mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 3:119,583,798...119,611,148
Ensembl chr 3:119,583,648...119,611,136
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCF2 mRNA; ESR2 protein affects the reaction [Raloxifene Hydrochloride results in decreased expression of NCF2 mRNA] Raloxifene Hydrochloride affects the expression of NCF2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
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G |
Ncl |
nucleolin |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NCL mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 9:93,369,119...93,377,643
Ensembl chr 9:93,368,932...93,377,643
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G |
Ncoa1 |
nuclear receptor coactivator 1 |
multiple interactions increases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA1 mRNA; Raloxifene Hydrochloride promotes the reaction [NCOA1 protein binds to IGF1 promoter] Raloxifene Hydrochloride results in increased expression of NCOA1 mRNA |
CTD |
PMID:17872375 PMID:19059307 PMID:19432593 |
|
NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
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G |
Ncoa2 |
nuclear receptor coactivator 2 |
multiple interactions increases expression |
ISO |
Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to PTGS2 promoter] Raloxifene Hydrochloride results in increased expression of NCOA2 protein |
CTD |
PMID:16739346 PMID:17872375 |
|
NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
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G |
Ncoa3 |
nuclear receptor coactivator 3 |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to IGF1 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to KLRC3 gene]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to PTGS2 promoter] |
CTD |
PMID:17395694 PMID:17872375 |
|
NCBI chr 3:162,692,176...162,788,582
Ensembl chr 3:162,692,185...162,787,548
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G |
Ncoa4 |
nuclear receptor coactivator 4 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NCOA4 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NCOA4 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr16:8,302,950...8,323,294
Ensembl chr16:8,302,950...8,323,293
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G |
Ncor2 |
nuclear receptor co-repressor 2 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to IGF1 promoter]; Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to PTGS2 promoter] Raloxifene Hydrochloride results in decreased expression of NCOR2 mRNA |
CTD |
PMID:17872375 PMID:19432593 |
|
NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
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G |
Ndrg4 |
NDRG family member 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NDRG4 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr19:9,766,439...9,802,396
Ensembl chr19:9,766,439...9,801,942
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G |
Ndufa2 |
NADH:ubiquinone oxidoreductase subunit A2 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NDUFA2 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr18:29,585,671...29,587,760
Ensembl chr18:29,585,671...29,587,760
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G |
Nectin1 |
nectin cell adhesion molecule 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of NECTIN1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 8:48,094,233...48,198,499
Ensembl chr 8:48,094,673...48,157,305
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G |
Nefl |
neurofilament light |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NEFL mRNA |
CTD |
PMID:14699072 |
|
NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
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G |
Nek7 |
NIMA-related kinase 7 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NEK7 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:55,485,759...55,617,534
Ensembl chr13:55,488,531...55,561,750
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G |
Nf1 |
neurofibromin 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NF1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
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G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFATC1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
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G |
Nfe2l1 |
nuclear factor, erythroid 2-like 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NFE2L1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
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G |
Nfil3 |
nuclear factor, interleukin 3 regulated |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NFIL3 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFIL3 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr17:12,261,102...12,276,316
Ensembl chr17:12,261,102...12,276,315
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP |
Raloxifene Hydrochloride promotes the reaction [NFKB1 protein binds to SLC1A2 promoter] |
CTD |
PMID:24782323 |
|
NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions affects expression decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NFKBIA mRNA Raloxifene Hydrochloride affects the expression of NFKBIA mRNA Raloxifene Hydrochloride results in decreased expression of NFKBIA mRNA |
CTD |
PMID:14699072 PMID:16298037 PMID:19059307 |
|
NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
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G |
Nfkbie |
NFKB inhibitor epsilon |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NFKBIE mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 9:17,828,405...17,835,240
Ensembl chr 9:17,828,408...17,835,240
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G |
Ninj1 |
ninjurin 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NINJ1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NLRP3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
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G |
Nme6 |
NME/NM23 nucleoside diphosphate kinase 6 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of NME6 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 8:117,920,912...117,928,148
Ensembl chr 8:117,920,944...117,928,195
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G |
Nmrk1 |
nicotinamide riboside kinase 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NMRK1 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 1:234,721,992...234,749,452
Ensembl chr 1:234,721,974...234,749,447
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
ISO EXP |
[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide; HMOX1 protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide]; XDH protein promotes the reaction [[Raloxifene Hydrochloride results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide] Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NOS2 protein] |
CTD |
PMID:15860553 PMID:20888885 |
|
NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
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G |
Nos3 |
nitric oxide synthase 3 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of NOS3 mRNA |
CTD |
PMID:11779577 |
|
NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
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G |
Notch3 |
notch receptor 3 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NOTCH3 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:14,138,495...14,189,688
Ensembl chr 7:14,138,495...14,189,688
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G |
Npm1 |
nucleophosmin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NPM1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
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G |
Npr2 |
natriuretic peptide receptor 2 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NPR2 mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of NPR2 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NPR2 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 5:59,128,186...59,147,321
Ensembl chr 5:59,128,315...59,147,255
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G |
Npy1r |
neuropeptide Y receptor Y1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of NPY1R mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr16:24,779,480...24,789,131
Ensembl chr16:24,779,477...24,788,740
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|
G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR1D1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:86,683,875...86,690,815
Ensembl chr10:86,683,875...86,690,815
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G |
Nr2f6 |
nuclear receptor subfamily 2, group F, member 6 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NR2F6 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NR2F6 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr16:19,769,968...19,777,414
Ensembl chr16:19,769,968...19,777,414
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR3C1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NR4A1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of NR4A3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
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G |
Nrep |
neuronal regeneration related protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of NREP mRNA |
CTD |
PMID:14699072 |
|
NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions increases expression |
ISO |
fulvestrant inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA]; Vehicle Emissions inhibits the reaction [Raloxifene Hydrochloride results in increased expression of NRF1 mRNA] |
CTD |
PMID:22105178 |
|
NCBI chr 4:57,335,732...57,445,317
Ensembl chr 4:57,378,069...57,445,341
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G |
Nrg1 |
neuregulin 1 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [[NRG1 protein co-treated with Estradiol] results in increased expression of MYC protein] |
CTD |
PMID:26502914 |
|
NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
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G |
Nrg2 |
neuregulin 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NRG2 mRNA |
CTD |
PMID:15849065 |
|
NCBI chr18:28,835,391...29,015,552
Ensembl chr18:28,835,417...29,015,552
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G |
Nuak1 |
NUAK family kinase 1 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of NUAK1 mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of NUAK1 mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 7:25,039,336...25,111,118
Ensembl chr 7:25,039,335...25,113,664
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G |
Nup160 |
nucleoporin 160 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of NUP160 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 3:79,496,239...79,562,163
Ensembl chr 3:79,498,179...79,551,128
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of NUS1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr20:33,557,052...33,584,011
Ensembl chr20:33,557,052...33,584,010
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G |
Nxf1 |
nuclear RNA export factor 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of NXF1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 1:224,957,535...224,970,728
Ensembl chr 1:224,957,517...224,970,727
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G |
Ocln |
occludin |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of OCLN mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
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G |
Olfm1 |
olfactomedin 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of OLFM1 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 3:6,761,031...6,798,739
Ensembl chr 3:6,773,813...6,798,737
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G |
Olfml2a |
olfactomedin-like 2A |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of OLFML2A mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 3:23,223,468...23,259,318
Ensembl chr 3:23,223,479...23,259,321
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G |
Olr1361 |
olfactory receptor 1361 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of OLR1361 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:12,332,142...12,333,083
Ensembl chr10:12,332,142...12,333,083
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G |
Olr1696 |
olfactory receptor 1696 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of OLR1696 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr20:878,460...879,425
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G |
Osbpl3 |
oxysterol binding protein-like 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of OSBPL3 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OSBPL3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 4:80,025,453...80,202,532
Ensembl chr 4:80,025,440...80,107,884
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G |
Osbpl7 |
oxysterol binding protein-like 7 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of OSBPL7 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr10:84,986,330...85,003,947
Ensembl chr10:84,986,328...85,004,562
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G |
Otub2 |
OTU deubiquitinase, ubiquitin aldehyde binding 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of OTUB2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 6:127,282,445...127,301,086
Ensembl chr 6:127,282,466...127,301,083
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G |
P2ry14 |
purinergic receptor P2Y14 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of P2RY14 mRNA] |
CTD |
PMID:18367319 |
|
NCBI chr 2:149,331,948...149,379,336
Ensembl chr 2:149,331,948...149,347,796
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G |
Palld |
palladin, cytoskeletal associated protein |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PALLD mRNA |
CTD |
PMID:14699072 |
|
NCBI chr16:31,865,712...31,948,168
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G |
Papola |
poly (A) polymerase alpha |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PAPOLA mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 6:129,609,068...129,662,002
Ensembl chr 6:129,609,074...129,661,531
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G |
Pappa1 |
pappalysin 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAPPA mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
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G |
Pawr |
pro-apoptotic WT1 regulator |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAWR mRNA; Raloxifene Hydrochloride results in increased expression of PAWR protein |
CTD |
PMID:20945400 |
|
NCBI chr 7:51,273,764...51,353,700
Ensembl chr 7:51,273,771...51,353,068
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G |
Pax5 |
paired box 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PAX5 mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 5:60,007,587...60,191,973
Ensembl chr 5:60,007,587...60,191,941
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G |
Pcdh7 |
protocadherin 7 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PCDH7 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr14:54,649,054...55,081,632
Ensembl chr14:55,072,200...55,081,551
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G |
Pcdhga3 |
protocadherin gamma subfamily A, 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PCDHGA3 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr18:30,820,151...30,971,113
Ensembl chr18:30,820,321...30,822,735
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G |
Pclaf |
PCNA clamp associated factor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PCLAF mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 8:71,514,281...71,526,182
Ensembl chr 8:71,514,281...71,526,182
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G |
Pcna |
proliferating cell nuclear antigen |
increases expression affects expression decreases expression |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of PCNA protein Raloxifene Hydrochloride affects the expression of PCNA protein Raloxifene Hydrochloride results in decreased expression of PCNA protein |
CTD |
PMID:15731164 PMID:16009171 PMID:17220163 |
|
NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
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G |
Pcolce |
procollagen C-endopeptidase enhancer |
affects expression increases expression |
EXP |
Raloxifene Hydrochloride affects the expression of PCOLCE mRNA Raloxifene Hydrochloride results in increased expression of PCOLCE mRNA |
CTD |
PMID:15576828 PMID:16079270 |
|
NCBI chr12:22,153,995...22,160,311
Ensembl chr12:22,153,983...22,160,337
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G |
Pctp |
phosphatidylcholine transfer protein |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PCTP mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:77,491,445...77,537,268
Ensembl chr10:77,491,454...77,512,032
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G |
Pdcd5 |
programmed cell death 5 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDCD5 mRNA |
CTD |
PMID:16202921 |
|
NCBI chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801 Ensembl chr 1:91,173,473...91,178,801
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G |
Pde3b |
phosphodiesterase 3B |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDE3B mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 1:183,892,841...184,078,071
Ensembl chr 1:183,892,841...184,078,071
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G |
Pde4d |
phosphodiesterase 4D |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PDE4D mRNA |
CTD |
PMID:16497877 |
|
NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
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G |
Pde5a |
phosphodiesterase 5A |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PDE5A mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
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G |
Pdgfra |
platelet derived growth factor receptor alpha |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PDGFRA mRNA |
CTD |
PMID:14699072 |
|
NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PDGFRB mRNA |
CTD |
PMID:14699072 |
|
NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
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G |
Pdlim3 |
PDZ and LIM domain 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PDLIM3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr16:49,543,140...49,574,362
Ensembl chr16:49,543,142...49,574,390
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G |
Pdp1 |
pyruvate dehydrogenase phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PDP1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 5:25,577,593...25,584,325
Ensembl chr 5:25,577,451...25,584,288
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G |
Pdyn |
prodynorphin |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PDYN mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 3:122,194,327...122,206,671
Ensembl chr 3:122,194,329...122,206,671
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G |
Pdzk1 |
PDZ domain containing 1 |
multiple interactions decreases expression |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PDZK1 mRNA] Raloxifene Hydrochloride results in decreased expression of PDZK1 mRNA |
CTD |
PMID:21185374 PMID:26865669 |
|
NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323
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G |
Per2 |
period circadian regulator 2 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of PER2 mRNA] |
CTD |
PMID:18728223 |
|
NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
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G |
Pex5 |
peroxisomal biogenesis factor 5 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PEX5 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 4:156,983,914...157,009,675
Ensembl chr 4:156,983,915...157,009,674 Ensembl chr 4:156,983,915...157,009,674
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G |
Pfkfb3 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PFKFB3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
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G |
Pgr |
progesterone receptor |
multiple interactions decreases expression increases expression |
ISO EXP |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of PGR mRNA] Raloxifene Hydrochloride results in decreased expression of PGR mRNA; Raloxifene Hydrochloride results in decreased expression of PGR protein Raloxifene Hydrochloride results in increased expression of PGR protein |
CTD |
PMID:11867264 PMID:16837883 PMID:16973256 PMID:21185374 PMID:26865669 |
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NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
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G |
Phc2 |
polyhomeotic homolog 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHC2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 5:146,832,552...146,931,444
Ensembl chr 5:146,882,756...146,931,444
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G |
Phf11 |
PHD finger protein 11 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PHF11 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr15:38,692,817...39,683,417
Ensembl chr15:38,647,779...38,709,984
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G |
Phlpp1 |
PH domain and leucine rich repeat protein phosphatase 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PHLPP mRNA |
CTD |
PMID:16079270 |
|
NCBI chr13:26,145,989...26,394,505
Ensembl chr13:26,172,243...26,394,505
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G |
Pias3 |
protein inhibitor of activated STAT, 3 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PIAS3 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 2:198,821,377...198,831,533
Ensembl chr 2:198,823,366...198,836,372
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G |
Pign |
phosphatidylinositol glycan anchor biosynthesis, class N |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PIGN mRNA |
CTD |
PMID:22841776 |
|
NCBI chr13:25,510,593...25,662,943
Ensembl chr13:25,513,892...25,652,473
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G |
Pigr |
polymeric immunoglobulin receptor |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PIGR mRNA |
CTD |
PMID:16079270 |
|
NCBI chr13:47,564,176...47,592,093
Ensembl chr13:47,572,219...47,591,699
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G |
Pik3r3 |
phosphoinositide-3-kinase regulatory subunit 3 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PIK3R3 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 5:135,069,972...135,145,633
Ensembl chr 5:135,074,297...135,142,488
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G |
Pim1 |
Pim-1 proto-oncogene, serine/threonine kinase |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PIM1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
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G |
Pitpnc1 |
phosphatidylinositol transfer protein, cytoplasmic 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PITPNC1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr10:95,429,879...95,697,734
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G |
Pla2g10 |
phospholipase A2, group X |
multiple interactions |
ISO |
Raloxifene Hydrochloride promotes the reaction [Estradiol results in increased expression of PLA2G10 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr10:1,509,732...1,520,970
Ensembl chr10:1,509,732...1,520,970
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G |
Pla2g7 |
phospholipase A2 group VII |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PLA2G7 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 9:19,935,754...19,978,013
Ensembl chr 9:19,935,768...19,978,013
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G |
Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLAT protein |
CTD |
PMID:16167916 |
|
NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of PLAU mRNA Raloxifene Hydrochloride results in decreased expression of PLAU protein |
CTD |
PMID:16277677 PMID:19059307 |
|
NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
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G |
Plaur |
plasminogen activator, urokinase receptor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PLAUR mRNA; Raloxifene Hydrochloride results in decreased expression of PLAUR protein |
CTD |
PMID:16277677 PMID:26865669 |
|
NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
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G |
Plekhf2 |
pleckstrin homology and FYVE domain containing 2 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLEKHF2 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 5:24,240,241...24,255,922
Ensembl chr 5:24,240,242...24,255,606
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G |
Plekhs1 |
pleckstrin homology domain containing S1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of PLEKHS1 mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 1:277,261,493...277,294,194
Ensembl chr 1:277,261,681...277,291,370
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G |
Plk3 |
polo-like kinase 3 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [IL1B protein results in increased expression of PLK3 mRNA] |
CTD |
PMID:12072388 |
|
NCBI chr 5:135,997,725...136,002,900
Ensembl chr 5:135,997,725...136,002,900
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G |
Plpp1 |
phospholipid phosphatase 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PLPP1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 2:44,664,076...44,726,820
Ensembl chr 2:44,664,124...44,726,689
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G |
Plpp3 |
phospholipid phosphatase 3 |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of PLPP3 mRNA ESR1 protein affects the reaction [Raloxifene Hydrochloride results in increased expression of PLPP3 mRNA] |
CTD |
PMID:14699072 |
|
NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
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G |
Plxnd1 |
plexin D1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PLXND1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 4:147,854,309...147,894,170
Ensembl chr 4:147,854,309...147,893,992
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G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PMAIP1 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
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G |
Pmp22 |
peripheral myelin protein 22 |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in decreased expression of PMP22 mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
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G |
Pms2 |
PMS1 homolog 2, mismatch repair system component |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PMS2 mRNA |
CTD |
PMID:16202921 |
|
NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
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G |
Podxl |
podocalyxin-like |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PODXL mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
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G |
Polm |
DNA polymerase mu |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of POLM mRNA |
CTD |
PMID:16497877 |
|
NCBI chr14:86,069,378...86,079,327
Ensembl chr14:86,069,016...86,078,954
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G |
Polr2b |
RNA polymerase II subunit B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of POLR2B mRNA |
CTD |
PMID:16514628 |
|
NCBI chr14:33,070,104...33,107,792
Ensembl chr14:33,070,078...33,107,776
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G |
Ppm1d |
protein phosphatase, Mg2+/Mn2+ dependent, 1D |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PPM1D mRNA |
CTD |
PMID:16514628 |
|
NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
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G |
Ppp1r10 |
protein phosphatase 1, regulatory subunit 10 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PPP1R10 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr20:3,329,677...3,344,286
Ensembl chr20:3,329,677...3,344,286
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G |
Ppp1r13b |
protein phosphatase 1, regulatory subunit 13B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PPP1R13B mRNA |
CTD |
PMID:16202921 |
|
NCBI chr 6:136,397,658...136,469,757
Ensembl chr 6:136,398,518...136,436,818
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression affects expression |
ISO EXP |
Raloxifene Hydrochloride results in increased expression of PPP1R15A mRNA Raloxifene Hydrochloride affects the expression of PPP1R15A mRNA |
CTD |
PMID:16079270 PMID:16497877 |
|
NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
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G |
Prdx2 |
peroxiredoxin 2 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PRDX2 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
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G |
Prkcz |
protein kinase C, zeta |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PRKCZ mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
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G |
Prkdc |
protein kinase, DNA-activated, catalytic subunit |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PRKDC mRNA |
CTD |
PMID:16514628 |
|
NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
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G |
Prl |
prolactin |
multiple interactions decreases secretion |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol promotes the reaction [GNRH1 protein results in increased secretion of PRL protein]]; Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased secretion of PRL protein] Raloxifene Hydrochloride results in decreased secretion of PRL protein |
CTD |
PMID:15950373 PMID:17054466 |
|
NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
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G |
Proc |
protein C, inactivator of coagulation factors Va and VIIIa |
decreases activity |
ISO |
Raloxifene Hydrochloride results in decreased activity of PROC protein |
CTD |
PMID:16359964 |
|
NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
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G |
Pros1 |
protein S |
affects expression decreases expression |
ISO |
Raloxifene Hydrochloride affects the expression of PROS1 protein Raloxifene Hydrochloride results in decreased expression of PROS1 protein |
CTD |
PMID:15850603 PMID:16202731 |
|
NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
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G |
Prpf4b |
pre-mRNA processing factor 4B |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PRPF4B mRNA |
CTD |
PMID:16497877 |
|
NCBI chr17:30,680,454...30,714,542
Ensembl chr17:30,683,640...30,714,495
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G |
Prss23 |
serine protease 23 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PRSS23 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 1:153,732,528...153,742,111
Ensembl chr 1:153,732,532...153,752,541
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G |
Psap |
prosaposin |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PSAP mRNA |
CTD |
PMID:16079270 |
|
NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875
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G |
Psmd14 |
proteasome 26S subunit, non-ATPase 14 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PSMD14 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 3:47,578,449...47,673,330
Ensembl chr 3:47,578,384...47,673,338
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G |
Psmd6 |
proteasome 26S subunit, non-ATPase 6 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PSMD6 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr15:12,407,557...12,416,153
Ensembl chr15:12,407,524...12,416,105
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G |
Psme1 |
proteasome activator subunit 1 |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PSME1 mRNA |
CTD |
PMID:16079270 |
|
NCBI chr15:34,256,071...34,258,947
Ensembl chr15:34,256,071...34,258,947
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G |
Psme4 |
proteasome activator subunit 4 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PSME4 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr14:115,166,165...115,269,041
Ensembl chr14:115,166,416...115,269,056
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G |
Ptgds |
prostaglandin D2 synthase |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with IL1B protein] results in increased expression of PTGDS mRNA |
CTD |
PMID:12072388 |
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NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
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G |
Ptger3 |
prostaglandin E receptor 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGER3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
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G |
Ptges |
prostaglandin E synthase |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of PTGES mRNA Raloxifene Hydrochloride results in decreased expression of PTGES mRNA |
CTD |
PMID:19059307 PMID:26865669 |
|
NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
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G |
Ptgfrn |
prostaglandin F2 receptor inhibitor |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PTGFRN mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 2:203,423,143...203,494,391
Ensembl chr 2:203,423,143...203,494,391
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G |
Ptgis |
prostaglandin I2 synthase |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of PTGIS mRNA |
CTD |
PMID:16079270 |
|
NCBI chr 3:163,950,746...163,986,129
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; Raloxifene Hydrochloride inhibits the reaction [NCOR2 protein binds to PTGS2 promoter]; Raloxifene Hydrochloride promotes the reaction [CREBBP protein binds to PTGS2 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR1 protein binds to PTGS2 promoter]; Raloxifene Hydrochloride promotes the reaction [ESR2 protein binds to PTGS2 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA2 protein binds to PTGS2 promoter]; Raloxifene Hydrochloride promotes the reaction [NCOA3 protein binds to PTGS2 promoter] Carrageenan inhibits the reaction [Raloxifene Hydrochloride results in increased expression of PTGS2 protein] Raloxifene Hydrochloride results in decreased expression of PTGS2 mRNA Raloxifene Hydrochloride results in increased expression of PTGS2 mRNA |
CTD |
PMID:15860553 PMID:17549036 PMID:17872375 PMID:19059307 |
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NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
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G |
Pth |
parathyroid hormone |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of PTH protein |
CTD |
PMID:17823083 |
|
NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
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G |
Ptp4a3 |
protein tyrosine phosphatase 4A3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTP4A3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 7:114,969,699...115,002,902
Ensembl chr 7:114,997,103...115,002,902
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G |
Ptpn13 |
protein tyrosine phosphatase, non-receptor type 13 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PTPN13 mRNA |
CTD |
PMID:15876410 |
|
NCBI chr14:7,688,551...7,863,664
Ensembl chr14:7,688,551...7,863,664
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G |
Ptpn4 |
protein tyrosine phosphatase, non-receptor type 4 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PTPN4 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr13:35,678,240...35,858,414
Ensembl chr13:35,678,240...35,858,390
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G |
Ptpn6 |
protein tyrosine phosphatase, non-receptor type 6 |
decreases activity |
ISO |
Raloxifene Hydrochloride results in decreased activity of PTPN6 protein |
CTD |
PMID:17272397 |
|
NCBI chr 4:157,239,141...157,263,890
Ensembl chr 4:157,239,142...157,263,890
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G |
Ptpre |
protein tyrosine phosphatase, receptor type, E |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of PTPRE mRNA [Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of PTPRE mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 1:207,820,719...207,987,123
Ensembl chr 1:207,887,209...207,987,136
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G |
Ptprh |
protein tyrosine phosphatase, receptor type, H |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PTPRH mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:72,809,935...72,859,161
Ensembl chr 1:72,810,545...72,859,161
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G |
Ptprr |
protein tyrosine phosphatase, receptor type, R |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of PTPRR mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 7:59,039,717...59,325,925
Ensembl chr 7:59,039,720...59,325,947
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G |
Ptx3 |
pentraxin 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of PTX3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
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G |
Pyy |
peptide YY |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of PYY mRNA |
CTD |
PMID:16202921 |
|
NCBI chr10:90,047,989...90,049,155
Ensembl chr10:90,047,993...90,049,112
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G |
Qk |
quaking |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with Estradiol] results in increased expression of QKI mRNA |
CTD |
PMID:21185374 |
|
NCBI chr 1:50,983,647...51,050,692
Ensembl chr 1:50,828,134...51,052,340
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G |
Rab11b |
RAB11B, member RAS oncogene family |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of RAB11B mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 7:18,598,991...18,612,132
Ensembl chr 7:18,598,880...18,612,147
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G |
Rab2a |
RAB2A, member RAS oncogene family |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of RAB2A mRNA |
CTD |
PMID:12154049 |
|
NCBI chr 5:21,632,654...21,696,721
Ensembl chr 5:21,632,926...21,695,519
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G |
Rab31 |
RAB31, member RAS oncogene family |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of RAB31 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 9:113,370,072...113,504,606
Ensembl chr 9:113,370,033...113,504,605
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G |
Rab40c |
Rab40c, member RAS oncogene family |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of RAB40C mRNA |
CTD |
PMID:19429434 |
|
NCBI chr10:15,247,913...15,283,111
Ensembl chr10:15,247,914...15,282,951
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G |
Racgap1 |
Rac GTPase-activating protein 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of RACGAP1 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 7:141,277,303...141,308,849
Ensembl chr 7:141,277,312...141,307,233
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G |
Rap1a |
RAP1A, member of RAS oncogene family |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of RAP1A mRNA |
CTD |
PMID:16514628 |
|
NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
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G |
Rapgefl1 |
Rap guanine nucleotide exchange factor like 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of RAPGEFL1 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr10:86,749,220...86,765,677
Ensembl chr10:86,763,117...86,765,675
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G |
Rara |
retinoic acid receptor, alpha |
affects expression |
EXP |
Raloxifene Hydrochloride affects the expression of RARA mRNA |
CTD |
PMID:16079270 |
|
NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
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G |
Rasa1 |
RAS p21 protein activator 1 |
increases expression |
EXP |
Raloxifene Hydrochloride results in increased expression of RASA1 mRNA |
CTD |
PMID:15576828 |
|
NCBI chr 2:13,617,021...13,696,531
Ensembl chr 2:13,616,822...13,696,426
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G |
Rasef |
RAS and EF hand domain containing |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of RASEF mRNA |
CTD |
PMID:19429434 |
|
NCBI chr 5:90,419,044...90,488,882
Ensembl chr 5:90,419,020...90,488,896
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G |
Rasgrf1 |
RAS protein-specific guanine nucleotide-releasing factor 1 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of RASGRF1 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 8:97,277,250...97,405,095
Ensembl chr 8:97,277,456...97,405,102
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G |
Rasgrp1 |
RAS guanyl releasing protein 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RASGRP1 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RASGRP1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
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G |
Rb1 |
RB transcriptional corepressor 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of RB1 mRNA |
CTD |
PMID:19429434 |
|
NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
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G |
Rbbp7 |
RB binding protein 7, chromatin remodeling factor |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of RBBP7 mRNA |
CTD |
PMID:16514628 |
|
NCBI chr X:33,648,682...33,665,821
Ensembl chr X:33,648,682...33,665,821
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G |
Rbbp8 |
RB binding protein 8, endonuclease |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of RBBP8 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr18:3,134,630...3,227,702
Ensembl chr18:3,162,543...3,227,688
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G |
Rbm10 |
RNA binding motif protein 10 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of RBM10 mRNA |
CTD |
PMID:16497877 |
|
NCBI chr X:1,754,869...1,786,973
Ensembl chr X:1,754,861...1,786,978
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G |
Rcan2 |
regulator of calcineurin 2 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RCAN2 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 9:19,518,568...19,749,145
Ensembl chr 9:19,518,558...19,749,145
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G |
Rcl1 |
RNA terminal phosphate cyclase-like 1 |
decreases expression |
ISO |
Raloxifene Hydrochloride results in decreased expression of RCL1 mRNA |
CTD |
PMID:26865669 |
|
NCBI chr 1:247,228,012...247,272,369
Ensembl chr 1:247,228,061...247,305,693
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G |
Rcor3 |
REST corepressor 3 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RCOR3 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr13:110,822,149...110,864,469
Ensembl chr13:110,822,150...110,864,469
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases activity |
ISO EXP |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Raloxifene Hydrochloride promotes the reaction [RELA protein binds to TERT protein]]; Raloxifene Hydrochloride affects the localization of and results in decreased activity of RELA protein; Raloxifene Hydrochloride inhibits the reaction [ESR1 protein binds to RELA protein]; Raloxifene Hydrochloride inhibits the reaction [RELA protein binds to CCL3 promoter]; Raloxifene Hydrochloride promotes the reaction [RELA protein binds to TERT protein] Raloxifene Hydrochloride results in decreased activity of RELA protein Raloxifene Hydrochloride promotes the reaction [RELA protein binds to SLC1A2 promoter]; Raloxifene Hydrochloride promotes the reaction [TERT protein binds to RELA protein] |
CTD |
PMID:15590986 PMID:16497877 PMID:16798746 PMID:24782323 |
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NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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G |
Rerg |
RAS-like, estrogen-regulated, growth-inhibitor |
multiple interactions |
ISO |
Raloxifene Hydrochloride inhibits the reaction [Estradiol results in increased expression of RERG mRNA] |
CTD |
PMID:21185374 |
|
NCBI chr 4:171,069,161...171,176,678
Ensembl chr 4:171,069,191...171,176,581
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G |
Ret |
ret proto-oncogene |
multiple interactions decreases expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RET mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RET mRNA Raloxifene Hydrochloride results in decreased expression of RET mRNA |
CTD |
PMID:19059307 PMID:26865669 |
|
NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
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|
G |
Retreg1 |
reticulophagy regulator 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RETREG1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 2:78,391,921...78,401,569
Ensembl chr 2:78,391,921...78,399,987 Ensembl chr 2:78,391,921...78,399,987
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G |
Rfk |
riboflavin kinase |
affects expression multiple interactions |
ISO |
Raloxifene Hydrochloride affects the expression of RFK mRNA [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RFK mRNA |
CTD |
PMID:14699072 PMID:19059307 |
|
NCBI chr 1:236,494,221...236,501,733
Ensembl chr 1:236,494,221...236,501,733
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G |
Rftn1 |
raftlin lipid raft linker 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RFTN1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr 9:12,740,885...12,942,358
Ensembl chr 9:12,740,885...12,942,358
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G |
Rgl1 |
ral guanine nucleotide dissociation stimulator,-like 1 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of RGL1 mRNA |
CTD |
PMID:19059307 |
|
NCBI chr13:69,909,122...70,174,590
Ensembl chr13:69,909,096...70,174,565
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G |
Rgs10 |
regulator of G-protein signaling 10 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of RGS10 mRNA |
CTD |
PMID:14699072 |
|
NCBI chr 1:199,782,076...199,823,440
Ensembl chr 1:199,782,078...199,823,386
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G |
Rgs13 |
regulator of G-protein signaling 13 |
affects expression |
ISO |
Raloxifene Hydrochloride affects the expression of RGS13 mRNA |
CTD |
PMID:14699072 |
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NCBI chr13:60,970,172...61,004,260
Ensembl chr13:60,970,247...61,003,744
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G |
Rgs16 |
regulator of G-protein signaling 16 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in decreased expression of RGS16 mRNA |
CTD |
PMID:19059307 |
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NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
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G |
Rgs4 |
regulator of G-protein signaling 4 |
multiple interactions |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RGS4 mRNA; [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of RGS4 mRNA |
CTD |
PMID:19059307 |
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NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
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G |
Rhbdf1 |
rhomboid 5 homolog 1 |
increases expression |
ISO |
Raloxifene Hydrochloride results in increased expression of RHBDF1 mRNA |
CTD |
PMID:26865669 |
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NCBI chr10:15,672,370...15,685,285
Ensembl chr10:15,672,382...15,685,284
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G |
Rhoa |
ras homolog family member A |
decreases expression |
EXP |
Raloxifene Hydrochloride results in decreased expression of RHOA mRNA |
CTD |
PMID:20970835 |
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NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
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G |
Rhobtb3 |
Rho-related BTB domain containing 3 |
multiple interactions affects expression |
ISO |
[Raloxifene Hydrochloride co-treated with ESR1 protein] results in increased expression of RHOBTB3 mRNA Raloxifene Hydrochloride affects the expression of RHOBTB3 mRNA |
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