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Pathways

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:methoxyisoflavone
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Accession:CHEBI:38756 term browser browse the term
Definition:Members of the class of isoflavones with at least one methoxy substituent.
Synonyms:related_synonym: methoxyisoflavones



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afrormosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects activity ISO afromosin affects the activity of ABCC1 protein CTD PMID:15796199 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
biochanin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO biochanin A inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]; biochanin A inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]; biochanin A promotes the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]; biochanin A promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]] CTD PMID:34217736 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity ISO biochanin A results in decreased activity of ABCC1 protein CTD PMID:15581599 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO biochanin A inhibits the reaction [ABCC2 protein affects the export of ochratoxin A] CTD PMID:15955639 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Ache acetylcholinesterase multiple interactions ISO [[sodium arsenite results in increased abundance of Arsenic] which co-treated with biochanin A] results in increased activity of ACHE protein; [coenzyme Q10 co-treated with biochanin A co-treated with Phloretin] inhibits the reaction [[sodium arsenite co-treated with Potassium Dichromate] results in decreased activity of ACHE protein]; biochanin A inhibits the reaction [[sodium arsenite co-treated with Potassium Dichromate] results in decreased activity of ACHE protein] CTD PMID:33410021 PMID:35547012 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
JBrowse link
G Agrn agrin decreases expression ISO biochanin A results in decreased expression of AGRN mRNA CTD PMID:12111696 NCBI chr 5:172,031,528...172,064,429
Ensembl chr 5:172,031,528...172,064,539
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
affects binding
ISO
EXP
AHR protein affects the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein binds to CYP1A1 promoter]]; biochanin A promotes the reaction [AHR protein binds to CYP1A1 promoter]
biochanin A results in increased activity of AHR protein
biochanin A binds to AHR protein
CTD PMID:16903077 PMID:28985473 PMID:31621310 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 decreases expression ISO biochanin A results in decreased expression of ALDH7A1 mRNA CTD PMID:12111696 NCBI chr18:52,208,035...52,240,293
Ensembl chr18:52,204,161...52,240,467
JBrowse link
G Arid5b AT-rich interaction domain 5B increases expression ISO biochanin A results in increased expression of ARID5B mRNA CTD PMID:12111696 NCBI chr20:20,305,693...20,489,689
Ensembl chr20:20,306,712...20,489,686
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 increases expression ISO biochanin A results in increased expression of BABAM2 mRNA CTD PMID:12111696 NCBI chr 6:30,089,065...30,467,508
Ensembl chr 6:30,071,611...30,467,341
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [coenzyme Q10 co-treated with biochanin A co-treated with Phloretin] inhibits the reaction [[sodium arsenite co-treated with Potassium Dichromate] results in decreased activity of BCHE protein]; biochanin A inhibits the reaction [[sodium arsenite co-treated with Potassium Dichromate] results in decreased activity of BCHE protein] CTD PMID:35547012 NCBI chr 2:160,607,289...160,699,760
Ensembl chr 2:160,606,288...160,699,760
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO biochanin A results in decreased expression of BCL2 protein CTD PMID:12791511 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO biochanin A results in decreased expression of BCL2L1 protein CTD PMID:12791511 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO biochanin A results in increased activity of CASP3 protein
biochanin A inhibits the reaction [Dextran Sulfate results in increased cleavage of CASP3 protein]
CTD PMID:12791511 PMID:38648921 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions ISO biochanin A inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of CAT protein] CTD PMID:33410021 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO biochanin A results in decreased expression of CDH2 mRNA CTD PMID:12111696 NCBI chr18:8,051,097...8,265,288
Ensembl chr18:8,051,097...8,265,288
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO biochanin A results in decreased expression of CDKN1A protein CTD PMID:12111696 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Ckb creatine kinase B increases activity ISO biochanin A results in increased activity of CKB protein CTD PMID:16621514 NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
JBrowse link
G Cldn1 claudin 1 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of CLDN1 protein] CTD PMID:38648921 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
decreases expression
decreases activity
ISO [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein; [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA; biochanin A binds to and results in decreased activity of CYP19A1 protein
biochanin A results in decreased expression of CYP19A1 mRNA
biochanin A results in decreased activity of CYP19A1 protein
CTD PMID:9435150 PMID:16965912 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases hydroxylation
decreases methylation
increases expression
increases activity
ISO AHR protein affects the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene promotes the reaction [AHR protein binds to CYP1A1 promoter]]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP1A1 protein]; biochanin A inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1A1 mRNA]; biochanin A promotes the reaction [AHR protein binds to CYP1A1 promoter]; Fulvestrant promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]; Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in increased hydroxylation of biochanin A
CYP1A1 protein results in decreased methylation of biochanin A
biochanin A results in increased activity of CYP1A1 protein
CTD PMID:15479032 PMID:16903077 PMID:28985473 PMID:31621310 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing
decreases activity
ISO
EXP
CYP1A2 protein results in increased metabolism of biochanin A
biochanin A results in decreased activity of CYP1A2 protein
CTD PMID:12814970 PMID:26278343 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases methylation
multiple interactions
increases expression
ISO CYP1B1 protein results in decreased methylation of biochanin A
Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]
AHR protein affects the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Butyric Acid promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; Sodium Acetate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]; sodium propionate promotes the reaction [biochanin A results in increased expression of CYP1B1 mRNA]
CTD PMID:15479032 PMID:28985473 PMID:31621310 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 affects activity
increases activity
increases expression
affects expression
ISO biochanin A affects the activity of CYP27B1 protein
biochanin A analog results in increased activity of CYP27B1 protein; biochanin A results in increased activity of CYP27B1 protein
biochanin A analog results in increased expression of CYP27B1 mRNA; biochanin A results in increased expression of CYP27B1 mRNA
biochanin A affects the expression of CYP27B1 mRNA; biochanin A analog affects the expression of CYP27B1 mRNA
CTD PMID:15795327 PMID:17659868 NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:64,756,626...64,761,570
JBrowse link
G Dera deoxyribose-phosphate aldolase decreases expression ISO biochanin A results in decreased expression of DERA mRNA CTD PMID:12111696 NCBI chr 4:172,394,971...172,473,746
Ensembl chr 4:172,394,962...172,490,142
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 decreases expression ISO biochanin A results in decreased expression of EIF5 mRNA CTD PMID:12111696 NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:136,407,440...136,418,821
JBrowse link
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 decreases expression ISO biochanin A results in decreased expression of ENPP5 mRNA CTD PMID:12111696 NCBI chr 9:24,407,574...24,415,029
Ensembl chr 9:24,408,218...24,414,867
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 decreases expression ISO biochanin A results in decreased expression of EPS15 mRNA CTD PMID:12111696 NCBI chr 5:129,274,487...129,374,856
Ensembl chr 5:129,274,502...129,374,856
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression
affects binding
ISO
EXP
biochanin A binds to and results in increased activity of ESR1 protein; biochanin A inhibits the reaction [Estradiol binds to ESR1 protein]
biochanin A results in decreased expression of ESR1 protein
[Fulvestrant co-treated with biochanin A] results in decreased expression of ESR1 protein; [Fulvestrant co-treated with biochanin A] results in increased expression of ESR1 mRNA
biochanin A binds to ESR1 protein
CTD PMID:9751507 PMID:12598185 PMID:14579009 PMID:16076101 PMID:19913605 More... NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
decreases expression
affects binding
ISO
EXP
biochanin A binds to and results in increased activity of ESR2 protein; biochanin A inhibits the reaction [Estradiol binds to ESR2 protein]
[Fulvestrant co-treated with biochanin A] results in increased expression of ESR2 mRNA; Fulvestrant inhibits the reaction [biochanin A results in decreased expression of ESR2 protein]
biochanin A results in increased expression of ESR2 mRNA
biochanin A binds to ESR2 protein
CTD PMID:9751507 PMID:12224631 PMID:16076101 PMID:16566672 PMID:19913605 More... NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions
affects binding
ISO biochanin A binds to and results in increased activity of ESRRA protein; biochanin A promotes the reaction [ESRRA protein binds to PNRC1 protein]
biochanin A binds to ESRRA protein mutant form
CTD PMID:14638870 NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811
JBrowse link
G Esrrb estrogen-related receptor beta multiple interactions ISO biochanin A binds to and results in increased activity of ESRRB protein; biochanin A promotes the reaction [ESRRB protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 6:111,738,662...111,894,087
Ensembl chr 6:111,738,662...111,894,087
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO biochanin A promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877
JBrowse link
G Fbl fibrillarin increases expression ISO biochanin A results in increased expression of FBL mRNA CTD PMID:12111696 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506
JBrowse link
G Folr1 folate receptor alpha decreases expression ISO biochanin A results in decreased expression of FOLR1 mRNA CTD PMID:12111696 NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:165,631,462...165,642,669
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase affects binding
decreases activity
decreases expression
ISO biochanin A binds to G6PD protein
biochanin A results in decreased activity of G6PD protein
biochanin A results in decreased expression of G6PD mRNA
CTD PMID:38266663 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144
JBrowse link
G Gm2a ganglioside GM2 activator decreases expression ISO biochanin A results in decreased expression of GM2A mRNA CTD PMID:12111696 NCBI chr10:39,719,919...39,732,452
Ensembl chr10:39,719,938...39,732,451
JBrowse link
G Gnai3 G protein subunit alpha i3 decreases expression ISO biochanin A results in decreased expression of GNAI3 mRNA CTD PMID:12111696 NCBI chr 2:198,430,920...198,468,874 JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO biochanin A results in decreased expression of GPX1 mRNA CTD PMID:12111696 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased expression of ICAM1 protein] CTD PMID:22387535 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions EXP [Fulvestrant co-treated with biochanin A] results in decreased expression of IGF1 mRNA CTD PMID:34848279 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:24,130,137...24,246,764
JBrowse link
G Il10 interleukin 10 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of IL10 protein] CTD PMID:38648921 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il17a interleukin 17A multiple interactions ISO biochanin A promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:25583575 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
JBrowse link
G Il18 interleukin 18 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein]; biochanin A inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL18 protein] CTD PMID:38764152 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; biochanin A inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein] CTD PMID:38648921 PMID:38764152 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il4 interleukin 4 increases expression ISO biochanin A results in increased expression of IL4 mRNA; biochanin A results in increased expression of IL4 protein CTD PMID:16169028 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
JBrowse link
G Il6 interleukin 6 multiple interactions ISO biochanin A inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA] CTD PMID:37016276 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased phosphorylation of LCK protein] CTD PMID:22387535 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267
JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 decreases expression ISO biochanin A results in decreased expression of LDLRAD4 mRNA CTD PMID:12111696 NCBI chr18:63,789,089...64,118,166
Ensembl chr18:63,790,440...64,113,064
JBrowse link
G Lxn latexin increases expression ISO biochanin A results in increased expression of LXN mRNA CTD PMID:12111696 NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein] CTD PMID:38764152 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein] CTD PMID:38764152 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of MKI67 protein] CTD PMID:38648921 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:199,926,150...199,952,593
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases expression ISO biochanin A results in decreased expression of MMP14 protein CTD PMID:16598420 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
decreases expression
ISO biochanin A results in decreased activity of MMP2 protein
biochanin A results in decreased expression of MMP2 mRNA
CTD PMID:16598420 PMID:38266663 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
decreases expression
ISO biochanin A results in decreased activity of MMP9 protein
biochanin A results in decreased expression of MMP9 mRNA
CTD PMID:16598420 PMID:38266663 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:38648921 PMID:38764152 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Mt2 metallothionein 2 increases expression ISO biochanin A results in increased expression of MT2A mRNA CTD PMID:10656621 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MTOR protein] CTD PMID:38648921 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of MUC2 protein] CTD PMID:38648921 NCBI chr 1:206,225,775...206,261,280
Ensembl chr 1:206,229,035...206,261,280
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO biochanin A promotes the reaction [RORC protein binds to NCOA1 protein] CTD PMID:25583575 NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 decreases expression ISO biochanin A results in decreased expression of NDUFA5 mRNA CTD PMID:12111696 NCBI chr 4:53,962,877...53,971,235
Ensembl chr 4:53,962,877...53,971,235
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [[sodium arsenite results in increased abundance of Arsenic] which co-treated with biochanin A] results in increased expression of NFE2L2 mRNA CTD PMID:33410021 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; biochanin A inhibits the reaction [pervanadate results in increased phosphorylation of NFKBIA protein]
biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]
CTD PMID:22387535 PMID:38764152 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nono non-POU domain containing, octamer-binding decreases expression ISO biochanin A results in decreased expression of NONO mRNA CTD PMID:12111696 NCBI chr  X:70,594,116...70,611,976
Ensembl chr  X:70,593,888...70,611,979
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO biochanin A inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] CTD PMID:38764152 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO biochanin A inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO biochanin A binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Ocln occludin multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of OCLN protein] CTD PMID:38648921 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G P2ry14 purinergic receptor P2Y14 decreases expression
multiple interactions
EXP biochanin A results in decreased expression of P2RY14 mRNA
Fulvestrant inhibits the reaction [biochanin A results in decreased expression of P2RY14 mRNA]
CTD PMID:34848279 NCBI chr 2:145,522,598...145,563,074
Ensembl chr 2:145,516,390...145,564,788
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO biochanin A results in increased cleavage of PARP1 protein CTD PMID:12791511 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of PCNA protein] CTD PMID:38648921 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pfdn5 prefoldin subunit 5 decreases expression ISO biochanin A results in decreased expression of PFDN5 mRNA CTD PMID:12111696 NCBI chr 7:135,330,364...135,335,102
Ensembl chr 7:135,330,172...135,335,099
JBrowse link
G Pgr progesterone receptor affects binding
multiple interactions
increases expression
ISO
EXP
biochanin A binds to PGR protein
Fulvestrant inhibits the reaction [biochanin A results in increased expression of PGR mRNA]
biochanin A inhibits the reaction [Progesterone binds to PGR protein]
CTD PMID:14579009 PMID:16076101 PMID:34848279 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression ISO biochanin A results in decreased expression of PLAUR protein CTD PMID:16598420 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 multiple interactions ISO biochanin A promotes the reaction [ESRRA protein binds to PNRC1 protein]; biochanin A promotes the reaction [ESRRB protein binds to PNRC1 protein]; biochanin A promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 5:52,443,400...52,489,303
Ensembl chr 5:52,443,400...52,446,491
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO biochanin A binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased phosphorylation of PRKAA1 protein] CTD PMID:38648921 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased expression of PTGS2 protein]
biochanin A inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]
CTD PMID:22387535 PMID:38764152 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rabl6 RAB, member RAS oncogene family-like 6 decreases expression ISO biochanin A results in decreased expression of RABL6 mRNA CTD PMID:12111696 NCBI chr 3:28,800,802...28,826,722
Ensembl chr 3:28,800,802...28,826,722
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions
ISO biochanin A results in decreased expression of RELA mRNA
biochanin A inhibits the reaction [Dextran Sulfate results in increased phosphorylation of RELA protein]
CTD PMID:12111696 PMID:38764152 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rif1 replication timing regulatory factor 1 decreases expression ISO biochanin A results in decreased expression of RIF1 mRNA CTD PMID:12111696 NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:56,963,854...57,017,106
JBrowse link
G Rorc RAR-related orphan receptor C multiple interactions ISO biochanin A promotes the reaction [RORC protein binds to NCOA1 protein] CTD PMID:25583575 NCBI chr 2:184,698,779...184,723,942
Ensembl chr 2:184,698,818...184,724,566
JBrowse link
G Rpusd3 RNA pseudouridine synthase D3 decreases expression ISO biochanin A results in decreased expression of RPUSD3 mRNA CTD PMID:12111696 NCBI chr 4:148,108,857...148,118,246
Ensembl chr 4:148,109,383...148,118,206
JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 increases expression ISO biochanin A results in increased expression of SH3GL1 mRNA CTD PMID:12111696 NCBI chr 9:929,459...956,922
Ensembl chr 9:928,563...956,890
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions EXP [biochanin A results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate CTD PMID:17108059 NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977
JBrowse link
G Slc25a3 solute carrier family 25 member 3 decreases expression ISO biochanin A results in decreased expression of SLC25A3 mRNA CTD PMID:12111696 NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309
JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 decreases activity
multiple interactions
EXP biochanin A results in decreased activity of SLCO1B1 protein
[biochanin A results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Bosentan; [biochanin A results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Methotrexate
CTD PMID:32259555 NCBI chr 4:176,197,736...176,244,401
Ensembl chr 4:176,197,741...176,244,395
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in increased expression of SQSTM1 protein] CTD PMID:38648921 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:35,026,598...35,037,750
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO biochanin A results in decreased expression of SRSF1 mRNA CTD PMID:12111696 NCBI chr10:73,335,519...73,342,549
Ensembl chr10:73,336,422...73,342,548
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases expression EXP biochanin A results in increased expression of SULT1A1 mRNA; biochanin A results in increased expression of SULT1A1 protein CTD PMID:20391625 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 increases expression EXP biochanin A results in increased expression of SULT1E1 mRNA; biochanin A results in increased expression of SULT1E1 protein CTD PMID:20391625 NCBI chr14:20,700,444...20,718,719
Ensembl chr14:20,700,292...20,718,716
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression EXP biochanin A results in increased expression of SULT2A1 mRNA; biochanin A results in increased expression of SULT2A1 protein CTD PMID:20391625 NCBI chr 1:84,582,011...84,639,001 JBrowse link
G Susd6 sushi domain containing 6 increases expression ISO biochanin A results in increased expression of SUSD6 mRNA CTD PMID:12111696 NCBI chr 6:106,130,183...106,262,900
Ensembl chr 6:106,169,118...106,262,900
JBrowse link
G Syk spleen associated tyrosine kinase multiple interactions ISO biochanin A inhibits the reaction [CXCL8 protein results in increased phosphorylation of SYK protein] CTD PMID:22387535 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO biochanin A binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of TJP1 protein] CTD PMID:38648921 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
biochanin A inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
biochanin A inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; biochanin A inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]
CTD PMID:16735947 PMID:38648921 PMID:38764152 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 decreases expression ISO biochanin A results in decreased expression of TNFRSF21 mRNA CTD PMID:12111696 NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:25,376,400...25,451,323
JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO biochanin A results in increased expression of TUBB mRNA CTD PMID:12111696 NCBI chr20:2,917,577...2,921,726
Ensembl chr20:2,917,539...2,921,726
JBrowse link
G Tyr tyrosinase increases expression ISO biochanin A results in increased expression of TYR mRNA CTD PMID:21071833 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 decreases expression ISO biochanin A results in decreased expression of UBE2D2 mRNA CTD PMID:12111696 NCBI chr18:27,638,399...27,680,386
Ensembl chr18:27,638,527...27,683,074
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
increases expression
ISO UGT1A1 protein results in increased glucuronidation of biochanin A
biochanin A results in increased expression of UGT1A1 mRNA
CTD PMID:14557274 PMID:31621310 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of biochanin A CTD PMID:14557274 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO biochanin A inhibits the reaction [Dextran Sulfate results in decreased phosphorylation of ULK1 protein] CTD PMID:38648921 NCBI chr12:51,511,492...51,537,746
Ensembl chr12:51,511,492...51,537,746
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
decreases expression
EXP biochanin A inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Fulvestrant inhibits the reaction [biochanin A results in decreased expression of VCAM1 protein] CTD PMID:16223672 PMID:16735947 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
JBrowse link
G Wdr74 WD repeat domain 74 decreases expression ISO biochanin A results in decreased expression of WDR74 mRNA CTD PMID:12111696 NCBI chr 1:215,060,901...215,065,687
Ensembl chr 1:215,060,961...215,066,336
JBrowse link
G Wwc2 WW and C2 domain containing 2 decreases expression ISO biochanin A results in decreased expression of WWC2 mRNA CTD PMID:12111696 NCBI chr16:50,991,096...51,154,529
Ensembl chr16:50,991,096...51,154,526
JBrowse link
calycosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd14b abhydrolase domain containing 14b increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of ABHD14B protein CTD PMID:24455688 NCBI chr 8:115,966,792...115,970,829
Ensembl chr 8:115,965,932...115,970,833
JBrowse link
G Ache acetylcholinesterase increases expression
multiple interactions
EXP 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of ACHE mRNA
7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of and results in increased activity of ACHE protein
CTD PMID:27019979 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Glycation End Products, Advanced results in increased expression of AGER protein] CTD PMID:36195188 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,151,965...4,155,685
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Glycation End Products, Advanced results in increased expression of APP protein] CTD PMID:36195188 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression
multiple interactions
EXP
ISO
7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of ATP5F1A mRNA
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A protein]
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A mRNA]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A protein]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A mRNA]]
CTD PMID:36436616 NCBI chr18:73,567,537...73,575,473
Ensembl chr18:73,567,526...73,575,922
JBrowse link
G Bace1 beta-secretase 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Glycation End Products, Advanced results in increased expression of BACE1 protein] CTD PMID:36195188 NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:55,038,823...55,064,918
JBrowse link
G Blvrb biliverdin reductase B increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of BLVRB protein CTD PMID:24455688 NCBI chr 1:91,866,258...91,883,921
Ensembl chr 1:91,866,258...91,884,225
JBrowse link
G Casp3 caspase 3 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Glycation End Products, Advanced results in increased expression of CASP3 protein] CTD PMID:36195188 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Ccnb1 cyclin B1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of CCNB1 mRNA CTD PMID:24455688 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CCND3 mRNA CTD PMID:24455688 NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:20,891,704...20,987,033
JBrowse link
G Ccng1 cyclin G1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of CCNG1 mRNA CTD PMID:24455688 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of CDK7 mRNA CTD PMID:24455688 NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CDKN1A mRNA CTD PMID:24455688 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CDKN1C mRNA CTD PMID:24455688 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of CDKN2D mRNA CTD PMID:24455688 NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:28,108,044...28,110,809
JBrowse link
G Epo erythropoietin increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of EPO mRNA CTD PMID:21309574 PMID:37348668 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725
JBrowse link
G Erp29 endoplasmic reticulum protein 29 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of ERP29 protein CTD PMID:24455688 NCBI chr12:40,750,177...40,756,607
Ensembl chr12:40,750,314...40,757,010
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Glycation End Products, Advanced results in decreased phosphorylation of GSK3B protein] CTD PMID:36195188 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:76,009,507...76,153,249
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased degradation of and results in increased expression of HIF1A protein modified form; 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of and results in decreased degradation of HIF1A protein
7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of HIF1A mRNA; 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of HIF1A protein
CTD PMID:21309574 PMID:37348668 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
JBrowse link
G Hmgb1 high mobility group box 1 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of HMGB1 protein CTD PMID:24455688 NCBI chr12:11,009,236...11,015,941
Ensembl chr16:39,039,050...39,041,327
Ensembl chr12:39,039,050...39,041,327
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein] CTD PMID:31726037 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA] CTD PMID:31726037 NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:50,204,551...50,222,891
JBrowse link
G Il33 interleukin 33 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein] CTD PMID:31726037 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:237,115,572...237,150,901
JBrowse link
G Il6 interleukin 6 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein] CTD PMID:31726037 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Krt1 keratin 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of KRT1 protein CTD PMID:24455688 NCBI chr 7:134,855,311...134,860,537
Ensembl chr 7:134,855,313...134,860,537
JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of LASP1 protein CTD PMID:24455688 NCBI chr10:83,290,820...83,331,989
Ensembl chr10:83,290,865...83,331,988
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased phosphorylation of MAPK1 protein CTD PMID:20686605 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased phosphorylation of MAPK3 protein CTD PMID:20686605 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Glycation End Products, Advanced results in increased phosphorylation of MAPT protein] CTD PMID:36195188 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,638,599...89,736,108
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of MCM5 mRNA CTD PMID:24455688 NCBI chr19:13,488,813...13,510,131
Ensembl chr19:13,488,813...13,517,758
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of MCM6 mRNA CTD PMID:24455688 NCBI chr13:42,379,161...42,404,352
Ensembl chr13:42,379,162...42,465,467
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 multiple interactions EXP
ISO
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 protein]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 protein]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 mRNA]] CTD PMID:36436616 NCBI chr 1:253,357,878...253,362,936
Ensembl chr 1:253,357,841...253,362,936
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein] CTD PMID:31726037 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of NME1 protein CTD PMID:24455688 NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of and affects the localization of NRF1 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NRF1 mRNA]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of ATP5F1A protein]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NDUFB8 protein]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB protein]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 protein]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of NRF1 mRNA]] CTD PMID:36436616 NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:59,632,372...59,738,353
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PEBP1 protein CTD PMID:24455688 NCBI chr12:44,946,307...44,967,890
Ensembl chr12:44,963,675...44,971,780
JBrowse link
G Pgam1 phosphoglycerate mutase 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PGAM1 protein CTD PMID:24455688 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:250,673,049...250,690,203
JBrowse link
G Pnpo pyridoxamine 5'-phosphate oxidase increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PNPO protein CTD PMID:24455688 NCBI chr10:82,421,027...82,427,288
Ensembl chr10:82,421,027...82,427,288
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Glycation End Products, Advanced results in decreased expression of PPARGC1A protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in increased acetylation of and affects the localization of PPARGC1A protein]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in increased acetylation of PPARGC1A protein]] CTD PMID:36195188 PMID:36436616 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PRDX1 protein CTD PMID:24455688 NCBI chr 5:135,383,906...135,399,504
Ensembl chr 5:135,383,906...135,399,504
JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of PRDX2 protein CTD PMID:24455688 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:128,103,175...128,154,865
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO [Calycosin cotreated with gallic acid] increases expression of PTGR1 mRNA in hepatocellular carcinoma cells RGD PMID:26265982 RGD:401959214 NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811
JBrowse link
G Rad9a RAD9 checkpoint clamp component A decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of RAD9A mRNA CTD PMID:24455688 NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:210,917,970...210,925,161
JBrowse link
G Rbx1 ring-box 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of RBX1 mRNA CTD PMID:24455688 NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:114,870,972...114,881,191
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein] CTD PMID:31726037 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions ISO
EXP
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB protein]
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB mRNA]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB protein]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB mRNA]]; SR18292 inhibits the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SDHB protein]]
CTD PMID:36436616 NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:158,547,689...158,569,667
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of SIRT1 protein] CTD PMID:36436616 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
G Skp1 S-phase kinase-associated protein 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of SKP1 mRNA CTD PMID:24455688 NCBI chr10:36,898,670...36,917,828
Ensembl chr10:36,903,078...36,918,308
JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in decreased expression of SKP2 mRNA CTD PMID:24455688 NCBI chr 2:59,888,406...59,916,471
Ensembl chr 2:59,888,413...59,916,438
JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of STIP1 protein CTD PMID:24455688 NCBI chr 1:213,638,641...213,657,654
Ensembl chr 1:213,638,641...213,657,654
JBrowse link
G Tagln2 transgelin 2 increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of TAGLN2 protein CTD PMID:24455688 NCBI chr13:87,499,350...87,506,328
Ensembl chr13:87,499,394...87,506,330
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [Glycation End Products, Advanced results in decreased expression of TFAM protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of TFAM mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of TFAM protein] CTD PMID:36195188 PMID:36436616 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein] CTD PMID:31726037 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein] CTD PMID:31726037 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnni3 troponin I3, cardiac type multiple interactions ISO 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in increased expression of TNNI3 protein] CTD PMID:36436616 NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:78,342,592...78,346,253
JBrowse link
G Ube3a ubiquitin protein ligase E3A increases expression ISO 7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of UBE3A mRNA CTD PMID:24455688 NCBI chr 1:119,204,244...119,297,097
Ensembl chr 1:119,206,148...119,297,097
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of 7,3'-dihydroxy-4'-methoxyisoflavone CTD PMID:25044472 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions
increases expression
ISO
EXP
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 protein]
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 protein]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 mRNA]]; NRF1 protein affects the reaction [7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [triptolide results in decreased expression of UQCRC2 protein]]
7,3'-dihydroxy-4'-methoxyisoflavone results in increased expression of UQCRC2 mRNA
CTD PMID:36436616 NCBI chr 1:184,599,240...184,629,804
Ensembl chr 1:184,599,212...184,630,946
JBrowse link
calycosin-7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein]
calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA; calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein
CTD PMID:36812960 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein]
calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA; calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein
CTD PMID:36812960 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression
ISO calycosin-7-O-beta-D-glucoside results in increased cleavage of CASP3 protein
TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased cleavage of CASP3 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of CASP3 mRNA]
CTD PMID:36812960 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase decreases expression ISO calycosin-7-O-beta-D-glucoside results in decreased expression of CAT protein CTD PMID:36812960 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Epo erythropoietin increases expression ISO calycosin-7-O-beta-D-glucoside results in increased expression of EPO mRNA CTD PMID:21309574 PMID:37348668 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725
JBrowse link
G Gpt glutamic--pyruvic transaminase decreases expression ISO calycosin-7-O-beta-D-glucoside results in decreased expression of GPT protein CTD PMID:36812960 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO calycosin-7-O-beta-D-glucoside results in decreased degradation of and results in increased expression of HIF1A protein modified form; calycosin-7-O-beta-D-glucoside results in increased expression of and results in decreased degradation of HIF1A protein
calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A mRNA; calycosin-7-O-beta-D-glucoside results in increased expression of HIF1A protein
CTD PMID:21309574 PMID:37348668 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
JBrowse link
G Txn1 thioredoxin 1 multiple interactions
decreases expression
ISO TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in decreased expression of BCL2 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased cleavage of CASP3 protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX mRNA]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of BAX protein]; TXN protein affects the reaction [calycosin-7-O-beta-D-glucoside results in increased expression of CASP3 mRNA]
calycosin-7-O-beta-D-glucoside results in decreased expression of TXN protein
calycosin-7-O-beta-D-glucoside results in decreased expression of TXN mRNA; calycosin-7-O-beta-D-glucoside results in decreased expression of TXN protein
CTD PMID:36812960 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
JBrowse link
formononetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
increases expression
affects activity
ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]; formononetin promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]]
formononetin results in decreased activity of ABCB1 protein
formononetin affects the activity of ABCB1 protein
CTD PMID:15796199 PMID:23867903 PMID:27996361 PMID:34217736 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects activity
decreases expression
multiple interactions
ISO formononetin affects the activity of ABCC1 protein
formononetin results in decreased expression of ABCC1 mRNA
Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC1 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCC1 mRNA]
CTD PMID:15796199 PMID:23867903 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases expression
ISO
EXP
Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]
formononetin promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA]
CTD PMID:23867903 PMID:28414026 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions EXP formononetin promotes the reaction [Cisplatin results in increased expression of ABCC4 mRNA] CTD PMID:28414026 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased activity of ACP5 protein]; formononetin inhibits the reaction [Streptozocin results in increased expression of ACP5 mRNA] CTD PMID:35315182 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO fulvestrant promotes the reaction [formononetin results in increased activity of AHR protein] CTD PMID:28985473 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO formononetin results in increased expression of AKR1B10 mRNA CTD PMID:37793997 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:64,007,420...64,020,847
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
ISO formononetin promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of AKT1 protein]]
formononetin decreases phosphorylation of AKT1 protein in lung
CTD
RGD
PMID:34077701 PMID:32276600 RGD:151357000 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
formononetin promotes the reaction [Epirubicin results in increased expression of BAX mRNA]
formononetin inhibits the reaction [Cisplatin results in increased expression of BAX protein]
CTD PMID:23867903 PMID:28414026 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
formononetin results in decreased expression of BCL2 mRNA
formononetin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]
formononetin promotes the reaction [Cisplatin results in increased expression of BCL2 protein]
CTD PMID:23867903 PMID:28414026 PMID:34077701 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of BIRC2 protein] CTD PMID:39855309 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:13,253,706...13,271,911
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
ISO
EXP
Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP3 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP3 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP3 mRNA]; formononetin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]; formononetin promotes the reaction [Epirubicin results in increased activity of CASP3 protein]; formononetin promotes the reaction [Epirubicin results in increased expression of CASP3 mRNA]
formononetin increases activity of CASP3 protein in lung
formononetin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]
CTD
RGD
PMID:23867903 PMID:28414026 PMID:34077701 PMID:32276600 RGD:151357000 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp7 caspase 7 multiple interactions ISO formononetin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP7 protein] CTD PMID:34077701 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
increases activity
ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP8 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP8 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP8 mRNA] CTD PMID:23867903 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP9 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP9 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP9 mRNA]; formononetin promotes the reaction [Epirubicin results in increased activity of CASP9 protein]; formononetin promotes the reaction [Epirubicin results in increased expression of CASP9 mRNA] CTD PMID:23867903 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Ccnb1 cyclin B1 increases expression
multiple interactions
ISO
EXP
formononetin results in increased expression of CCNB1 protein
XI-006 inhibits the reaction [formononetin results in increased expression of CCNB1 protein]
CTD PMID:28414026 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
EXP
ISO
formononetin results in increased expression of CCND1 protein
XI-006 inhibits the reaction [formononetin results in increased expression of CCND1 protein]
CTD PMID:28414026 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO formononetin results in increased expression of CPT1A mRNA CTD PMID:37793997 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
JBrowse link
G Ctsk cathepsin K multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK protein] CTD PMID:35315182 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases hydroxylation
increases expression
multiple interactions
decreases methylation
ISO CYP1A1 protein results in increased hydroxylation of formononetin
formononetin results in increased expression of CYP1A1 mRNA
fulvestrant promotes the reaction [formononetin results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in decreased methylation of formononetin
CTD PMID:15479032 PMID:28985473 PMID:37793997 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO
EXP
formononetin results in decreased activity of CYP1A2 protein CTD PMID:26278343 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases methylation
increases expression
ISO CYP1B1 protein results in decreased methylation of formononetin
formononetin results in increased expression of CYP1B1 mRNA
CTD PMID:15479032 PMID:28985473 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO formononetin results in decreased activity of CYP2D6 protein CTD PMID:26278343 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation ISO formononetin decreases phosphorylation of EGFR protein in lung RGD PMID:32276600 RGD:151357000 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Epo erythropoietin increases expression ISO formononetin results in increased expression of EPO mRNA CTD PMID:21309574 PMID:37348668 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO formononetin binds to ESR1 protein
[Lipopolysaccharides co-treated with formononetin] results in increased expression of ESR1 protein
formononetin binds to and results in increased activity of ESR1 protein
CTD PMID:9751507 PMID:16076101 PMID:16773531 PMID:37269934 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
ISO formononetin binds to and results in increased activity of ESR2 protein
formononetin binds to ESR2 protein
CTD PMID:9751507 PMID:12224631 PMID:16076101 PMID:16773531 PMID:19913605 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of FOS mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of FOS protein] CTD PMID:35315182 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [formononetin co-treated with Hydrogen Peroxide] results in increased expression of GCLM protein; formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]]; Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]] CTD PMID:34077701 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP formononetin inhibits the reaction [Cisplatin results in increased expression of HAVCR1 mRNA] CTD PMID:28414026 NCBI chr10:31,619,914...31,652,955
Ensembl chr10:31,619,897...31,653,268
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
ISO formononetin results in increased expression of HIF1A mRNA; formononetin results in increased expression of HIF1A protein
formononetin results in decreased degradation of and results in increased expression of HIF1A protein modified form; formononetin results in increased expression of and results in decreased degradation of HIF1A protein
CTD PMID:21309574 PMID:37348668 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO
EXP
[formononetin co-treated with Hydrogen Peroxide] results in increased expression of HMOX1 protein; formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]]; Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]]
formononetin inhibits the reaction [Glucose results in decreased expression of HMOX1 mRNA]
CTD PMID:34077701 PMID:37944786 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Il17a interleukin 17A multiple interactions ISO formononetin promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:25583575 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL1B protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of IL1B mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:39855309 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il4 interleukin 4 increases expression ISO formononetin results in increased expression of IL4 mRNA; formononetin results in increased expression of IL4 protein CTD PMID:16108819 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
JBrowse link
G Il6 interleukin 6 multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of IL6 protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of IL6 mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:37269934 PMID:39855309 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of JUN protein] CTD PMID:35315182 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO formononetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]
formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK1 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]
CTD PMID:34077701 PMID:39855309 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK11 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK11 protein] CTD PMID:39855309 NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK12 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK12 protein] CTD PMID:39855309 NCBI chr 7:122,085,647...122,096,307
Ensembl chr 7:122,085,913...122,096,307
JBrowse link
G Mapk13 mitogen activated protein kinase 13 multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK13 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK13 protein] CTD PMID:39855309 NCBI chr20:6,836,979...6,847,197
Ensembl chr20:6,837,013...6,847,191
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK14 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK14 protein] CTD PMID:39855309 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO formononetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]
formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK3 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]
CTD PMID:34077701 PMID:39855309 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO formononetin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]
formononetin inhibits the reaction [Dextran Sulfate results in increased phosphorylation of MAPK8 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]
CTD PMID:34077701 PMID:39855309 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Matn3 matrilin 3 decreases expression ISO formononetin results in decreased expression of MATN3 mRNA CTD PMID:37793997 NCBI chr 6:37,467,729...37,487,776
Ensembl chr 6:37,467,729...37,487,776
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression ISO formononetin decreases expression of MCL1 protein in lung RGD PMID:32276600 RGD:151357000 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:185,908,168...185,938,782
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP formononetin results in increased expression of MDM2 protein CTD PMID:28414026 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:55,176,560...55,200,791
JBrowse link
G Mdm4 MDM4 regulator of p53 increases expression EXP formononetin results in increased expression of MDM4 protein CTD PMID:28414026 NCBI chr13:46,922,236...47,068,241
Ensembl chr13:46,958,298...47,026,372
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 protein] CTD PMID:35315182 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 protein] CTD PMID:35315182 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [formononetin co-treated with Hydrogen Peroxide] results in increased expression of NFE2L2 mRNA; formononetin promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 mRNA]; NFE2L2 protein affects the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of GCLM mRNA]]; NFE2L2 protein affects the reaction [formononetin promotes the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]]; Wortmannin inhibits the reaction [formononetin promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]]
formononetin inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in decreased expression of NFE2L2 protein]
CTD PMID:34077701 PMID:37269934 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO formononetin inhibits the reaction [CXCL8 protein results in increased phosphorylation of NFKBIA protein]
formononetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
CTD PMID:22387535 PMID:39855309 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Ngf nerve growth factor multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of NGF mRNA]; formononetin inhibits the reaction [Glucose results in decreased secretion of and results in decreased expression of NGF protein] CTD PMID:37944786 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:192,589,582...192,643,834
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein] CTD PMID:37269934 PMID:39855309 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:39855309 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions
EXP formononetin results in increased expression of NOS3 mRNA
formononetin results in increased phosphorylation of and results in increased activity of NOS3 protein
CTD PMID:19570671 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 mRNA; [formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 protein; NFE2L2 protein affects the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 mRNA]; Wortmannin inhibits the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of NQO1 mRNA] CTD PMID:34077701 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Pgc progastricsin decreases expression ISO formononetin results in decreased expression of PGC mRNA CTD PMID:37793997 NCBI chr 9:20,755,002...20,763,220
Ensembl chr 9:20,755,002...20,763,220
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in decreased localization of PPARG protein]; formononetin inhibits the reaction [Lipopolysaccharides results in decreased expression of PPARG mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in decreased localization of PPARG protein] CTD PMID:39855309 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of PPARGC1A mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of PPARGC1A protein] CTD PMID:37944786 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation
multiple interactions
ISO formononetin results in increased phosphorylation of PRKAA1 protein
Lipopolysaccharides promotes the reaction [formononetin results in increased phosphorylation of PRKAA1 protein]
CTD PMID:37269934 NCBI chr 2:55,967,766...56,003,450
Ensembl chr 2:55,967,351...56,003,450
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 multiple interactions
increases phosphorylation
ISO Lipopolysaccharides promotes the reaction [formononetin results in increased phosphorylation of PRKAA2 protein] CTD PMID:37269934 NCBI chr 5:125,036,945...125,109,010
Ensembl chr 5:125,042,179...125,108,324
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta multiple interactions ISO [Lipopolysaccharides co-treated with formononetin] results in increased phosphorylation of PRKACB protein CTD PMID:37269934 NCBI chr 2:238,297,140...238,389,317
Ensembl chr 2:238,300,127...238,386,315
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO [Formononetin cotreated with gallic acid] increases expression of PTGR1 mRNA in hepatocellular carcinoma cells RGD PMID:26265982 RGD:401959214 NCBI chr 5:78,579,060...78,597,671
Ensembl chr 5:78,579,057...78,597,811
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:37269934 PMID:39855309 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in increased localization of RELA protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased localization of RELA protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA] CTD PMID:39855309 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Sirt1 sirtuin 1 multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of SIRT1 mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of SIRT1 protein] CTD PMID:37944786 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
G Sirt3 sirtuin 3 affects binding
multiple interactions
EXP formononetin binds to SIRT3 protein
formononetin inhibits the reaction [Glucose results in decreased expression of SIRT3 mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of SIRT3 protein]
CTD PMID:37944786 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases expression EXP formononetin results in decreased expression of SLC22A2 mRNA CTD PMID:28414026 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Slc6a14 solute carrier family 6 member 14 decreases expression ISO formononetin results in decreased expression of SLC6A14 mRNA CTD PMID:37793997 NCBI chr  X:117,109,063...117,169,522
Ensembl chr  X:117,108,947...117,169,828
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of SOD1 mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of SOD1 protein] CTD PMID:37944786 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP
ISO
formononetin inhibits the reaction [Glucose results in decreased expression of SOD2 mRNA]; formononetin inhibits the reaction [Glucose results in decreased expression of SOD2 protein]
formononetin inhibits the reaction [Dextran Sulfate results in decreased expression of SOD2 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD2 protein]
CTD PMID:37944786 PMID:39855309 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO [Lipopolysaccharides co-treated with formononetin] results in increased phosphorylation of STK11 protein CTD PMID:37269934 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:10,225,204...10,241,965
JBrowse link
G Tagln transgelin decreases expression ISO formononetin results in decreased expression of TAGLN mRNA CTD PMID:37793997 NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:55,121,301...55,127,563
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of TFAM mRNA] CTD PMID:37944786 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877
JBrowse link
G Tfb2m transcription factor B2, mitochondrial multiple interactions EXP formononetin inhibits the reaction [Glucose results in decreased expression of TFB2M mRNA] CTD PMID:37944786 NCBI chr13:93,810,859...93,828,678
Ensembl chr13:93,810,731...93,828,594
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein] CTD PMID:37269934 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO formononetin inhibits the reaction [Dextran Sulfate results in increased expression of and results in increased secretion of TNF protein]; formononetin inhibits the reaction [Dextran Sulfate results in increased expression of TNF mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; formononetin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:39855309 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression
EXP
ISO
formononetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]
formononetin results in decreased expression of TP53 protein
XI-006 inhibits the reaction [formononetin results in decreased expression of TP53 protein]
CTD PMID:28414026 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV5 mRNA] CTD PMID:35315182 NCBI chr 4:71,503,085...71,531,134
Ensembl chr 4:71,503,093...71,529,384
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions ISO formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV6 mRNA] CTD PMID:35315182 NCBI chr 4:71,474,006...71,489,667
Ensembl chr 4:71,474,007...71,489,671
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO formononetin results in increased expression of TXNIP mRNA CTD PMID:37793997 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 mRNA; [formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 protein; NFE2L2 protein affects the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 mRNA]; Wortmannin inhibits the reaction [[formononetin co-treated with Hydrogen Peroxide] results in increased expression of TXNRD1 mRNA] CTD PMID:34077701 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
increases expression
ISO UGT1A1 protein results in increased glucuronidation of formononetin
formononetin results in increased expression of UGT1A1 mRNA
CTD PMID:14557274 PMID:37793997 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of formononetin CTD PMID:14557274 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
glycitein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA CTD PMID:16963248 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO glycitein inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]; glycitein promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Daunorubicin]]; glycitein promotes the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]] CTD PMID:34217736 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:87,563,601...87,613,097
JBrowse link
G Add2 adducin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ADD2 mRNA CTD PMID:16963248 NCBI chr 4:120,001,977...120,101,090
Ensembl chr 4:120,002,054...120,101,091
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity ISO glycitein results in increased activity of AHR protein CTD PMID:17869316 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO glycitein results in decreased expression of ARHGDIA mRNA CTD PMID:15757668 NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:105,818,203...105,850,379
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ATP6V0A2 mRNA CTD PMID:16963248 NCBI chr12:37,608,211...37,640,860
Ensembl chr12:37,472,813...37,640,860
JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of BAZ1A mRNA CTD PMID:16963248 NCBI chr 6:78,124,872...78,247,672
Ensembl chr 6:78,124,872...78,247,648
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:64,106,809...64,135,749
Ensembl chr 4:64,106,804...64,135,627
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:83,486,396...83,499,421
Ensembl chr 1:83,486,396...83,499,421
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO glycitein results in decreased expression of CCNA2 CTD PMID:21161820 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO glycitein results in increased expression of CCND1 mRNA CTD PMID:19800779 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:69,392,943...69,427,213
Ensembl chr11:69,392,975...69,427,128
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity ISO glycitein results in decreased activity of CDK4 protein CTD PMID:21161820 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO ESR2 affects the reaction [glycitein results in increased expression of CDKN1A] CTD PMID:21161820 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:38,923,154...38,997,881
Ensembl chr12:38,922,330...38,954,783
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:76,342,231...76,369,846
Ensembl chr 3:76,342,404...76,370,061
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:196,661,465...196,680,505
Ensembl chr 2:196,661,345...196,682,397
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
JBrowse link
G Dock3 dedicator of cyto-kinesis 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of DOCK3 mRNA CTD PMID:16963248 NCBI chr 8:116,431,158...116,782,218
Ensembl chr 8:116,431,159...116,782,195
JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:1,098,505...1,133,500
Ensembl chr 9:1,095,929...1,177,715
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:197,869,873...197,908,693
Ensembl chr 1:197,870,962...197,908,731
JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798
JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of EPHA1 mRNA CTD PMID:16963248 NCBI chr 4:72,213,022...72,227,543
Ensembl chr 4:72,213,037...72,227,474
JBrowse link
G Espn espin multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ESPN mRNA CTD PMID:16963248 NCBI chr 5:167,909,271...167,943,168
Ensembl chr 5:167,909,271...167,942,984
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
ISO glycitein inhibits the reaction [Estradiol binds to ESR1 protein]
glycitein binds to ESR1 protein
CTD PMID:14579009 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects response to substance
ISO
EXP
ESR2 affects the reaction [glycitein results in increased expression of CDKN1A]
[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA
ESR2 affects the susceptibility to glycitein
CTD PMID:21161820 PMID:28964809 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:87,894,049...87,904,213
Ensembl chr10:87,893,543...87,904,247
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:64,959,999...64,975,176
Ensembl chr 4:64,959,999...64,975,176
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:181,536,665...181,546,830
Ensembl chr 3:181,536,673...181,546,834
JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:30,595,082...30,598,007
Ensembl chr20:30,595,084...30,597,844
Ensembl chr 6:30,595,084...30,597,844
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:30,484,600...30,599,898
Ensembl chr 7:30,484,600...30,595,806
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326
JBrowse link
G Fmn2 formin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of FMN2 mRNA CTD PMID:16963248 NCBI chr13:88,986,863...89,303,789
Ensembl chr13:88,986,842...89,303,789
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:7,233,524...7,273,290
Ensembl chr16:7,233,606...7,273,285
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:238,054,954...238,063,451
Ensembl chr11:58,096,362...58,096,565
Ensembl chr 2:58,096,362...58,096,565
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:91,938,308...91,948,680
Ensembl chr 1:91,938,278...91,948,683
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:65,165,532...65,634,681
Ensembl chr13:65,165,532...65,634,519
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Ifrd2 interferon-related developmental regulator 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IFRD2 mRNA CTD PMID:16963248 NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Irf2bp1 interferon regulatory factor 2 binding protein 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IRF2BP1 mRNA CTD PMID:16963248 NCBI chr 1:87,780,782...87,783,483
Ensembl chr 1:87,779,406...87,785,661
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:175,694,638...175,704,125
Ensembl chr 2:175,695,615...175,705,095
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity ISO glycitein results in increased activity of JUN protein CTD PMID:17088408 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Kcng2 potassium voltage-gated channel modifier subfamily G member 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA CTD PMID:16963248 NCBI chr18:76,017,225...76,085,377
Ensembl chr18:76,018,047...76,083,688
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:155,238,124...155,316,121
Ensembl chr 4:155,238,044...155,316,121
JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:126,254,633...126,274,412
Ensembl chr 3:126,254,663...126,274,418
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:152,239,296...152,262,290
Ensembl chr 5:152,229,505...152,262,290
JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:49,305,693...49,347,970
Ensembl chr13:49,305,830...49,348,116
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:1,034,679...1,037,337
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:95,313,830...95,329,471
Ensembl chr 1:95,313,033...95,329,354
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
glycitein results in increased phosphorylation of MAPK1 protein
CTD PMID:17088408 PMID:20188714 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]
glycitein results in increased phosphorylation of MAPK3 protein
CTD PMID:17088408 PMID:20188714 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO glycitein results in decreased expression of MMP3 mRNA; glycitein results in decreased expression of MMP3 protein CTD PMID:20188714 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]
glycitein results in decreased expression of MMP9 mRNA; glycitein results in decreased expression of MMP9 protein
CTD PMID:20188714 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:30,545,794...30,553,987
Ensembl chr 6:30,545,794...30,553,987
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:186,410,851...186,421,024
Ensembl chr 2:186,412,291...186,421,026
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
ISO glycitein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; glycitein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
glycitein results in decreased activity of NOS2 protein
CTD PMID:11308324 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO glycitein results in increased expression of NRIP1 mRNA CTD PMID:15757668 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353
JBrowse link
G Olfml3 olfactomedin-like 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of OLFML3 mRNA CTD PMID:16963248 NCBI chr 2:193,932,665...193,935,494
Ensembl chr 2:193,932,665...193,935,494
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO glycitein results in decreased expression of PCNA CTD PMID:21161820 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pdlim2 PDZ and LIM domain 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PDLIM2 mRNA CTD PMID:16963248 NCBI chr15:51,647,195...51,659,904
Ensembl chr15:51,647,197...51,658,958
JBrowse link
G Pnn pinin, desmosome associated protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PNN mRNA CTD PMID:16963248 NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933
JBrowse link
G Pou4f2 POU class 4 homeobox 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of POU4F2 mRNA CTD PMID:16963248 NCBI chr19:46,390,958...46,394,599
Ensembl chr19:46,390,958...46,394,599
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:58,036,779...58,098,996
Ensembl chr 3:58,038,042...58,099,363
JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:34,941,445...35,027,460
Ensembl chr15:34,967,477...35,026,828
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:119,572,295...119,597,405
Ensembl chr 8:119,575,868...119,598,108
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:45,189,768...45,255,277
Ensembl chr13:45,189,804...45,255,277
JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:69,073,681...69,194,041
Ensembl chr 7:69,075,562...69,194,102
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO glycitein results in increased expression of RPS6KA3 mRNA CTD PMID:15757668 NCBI chr  X:39,325,926...39,432,017
Ensembl chr  X:39,325,926...39,433,678
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197
JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:48,457,102...48,470,444
Ensembl chr12:48,456,932...48,473,154
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA CTD PMID:16963248 NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:100,161,024...100,182,259
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:102,953,894...102,962,964
Ensembl chr 1:102,953,918...102,962,964
JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO glycitein results in decreased expression of SLC12A2 mRNA CTD PMID:15757668 NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases uptake ISO SLC22A8 protein results in increased uptake of glycitein analog CTD PMID:21244849 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:79,478,804...79,608,118
Ensembl chr 5:79,478,912...79,607,052
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions
increases activity
ISO glycitein promotes the reaction [SP1 protein binds to VDR promoter]; U 0126 inhibits the reaction [glycitein results in increased activity of SP1 protein] CTD PMID:17088408 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:135,420,050...135,450,513
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:77,920,781...77,939,284
Ensembl chr 1:77,920,783...77,938,574
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
JBrowse link
G Stc1 stanniocalcin 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNA CTD PMID:16963248 NCBI chr15:50,709,439...50,720,093
Ensembl chr15:50,709,415...50,720,082
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:26,544,059...26,576,365
Ensembl chr12:26,544,067...26,576,366
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:68,572,901...68,602,803
Ensembl chr 9:68,572,911...68,602,890
JBrowse link
G Tacr3 tachykinin receptor 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of TACR3 mRNA CTD PMID:16963248 NCBI chr 2:225,940,497...226,037,756
Ensembl chr 2:225,940,444...226,037,756
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:126,526,006...126,622,163
Ensembl chr 6:126,526,009...126,614,215
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA CTD PMID:16963248 NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:56,911,252...56,930,796
JBrowse link
G Tp53 tumor protein p53 increases expression ISO glycitein results in increased expression of TP53 protein CTD PMID:19800779 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 decreases expression
multiple interactions
ISO glycitein results in decreased expression of TP53I11 mRNA
[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA
CTD PMID:15757668 PMID:27424125 NCBI chr 3:99,600,213...99,615,462
Ensembl chr 3:99,600,159...99,615,432
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of UCHL1 mRNA CTD PMID:16963248 NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,838,861...41,849,417
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:14,317,083...14,343,724
Ensembl chr 5:14,316,918...14,347,778
JBrowse link
G Vdr vitamin D receptor multiple interactions
increases expression
ISO fulvestrant inhibits the reaction [glycitein results in increased expression of VDR protein]; glycitein promotes the reaction [SP1 protein binds to VDR promoter]; U 0126 inhibits the reaction [glycitein results in increased expression of VDR protein]
glycitein results in increased expression of VDR mRNA; glycitein results in increased expression of VDR protein
CTD PMID:17088408 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757
JBrowse link
glycitin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:87,563,601...87,613,097
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP glycitin inhibits the reaction [APP protein binds to APP protein] CTD PMID:17323972 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:105,818,203...105,850,379
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:64,106,809...64,135,749
Ensembl chr 4:64,106,804...64,135,627
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:83,486,396...83,499,421
Ensembl chr 1:83,486,396...83,499,421
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:69,392,943...69,427,213
Ensembl chr11:69,392,975...69,427,128
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:38,923,154...38,997,881
Ensembl chr12:38,922,330...38,954,783
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:76,342,231...76,369,846
Ensembl chr 3:76,342,404...76,370,061
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:196,661,465...196,680,505
Ensembl chr 2:196,661,345...196,682,397
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:1,098,505...1,133,500
Ensembl chr 9:1,095,929...1,177,715
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:197,869,873...197,908,693
Ensembl chr 1:197,870,962...197,908,731
JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:87,894,049...87,904,213
Ensembl chr10:87,893,543...87,904,247
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:64,959,999...64,975,176
Ensembl chr 4:64,959,999...64,975,176
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:181,536,665...181,546,830
Ensembl chr 3:181,536,673...181,546,834
JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:30,595,082...30,598,007
Ensembl chr20:30,595,084...30,597,844
Ensembl chr 6:30,595,084...30,597,844
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:30,484,600...30,599,898
Ensembl chr 7:30,484,600...30,595,806
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:7,233,524...7,273,290
Ensembl chr16:7,233,606...7,273,285
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:238,054,954...238,063,451
Ensembl chr11:58,096,362...58,096,565
Ensembl chr 2:58,096,362...58,096,565
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:91,938,308...91,948,680
Ensembl chr 1:91,938,278...91,948,683
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:65,165,532...65,634,681
Ensembl chr13:65,165,532...65,634,519
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:175,694,638...175,704,125
Ensembl chr 2:175,695,615...175,705,095
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:155,238,124...155,316,121
Ensembl chr 4:155,238,044...155,316,121
JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:126,254,633...126,274,412
Ensembl chr 3:126,254,663...126,274,418
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:152,239,296...152,262,290
Ensembl chr 5:152,229,505...152,262,290
JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:49,305,693...49,347,970
Ensembl chr13:49,305,830...49,348,116
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:1,034,679...1,037,337
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:95,313,830...95,329,471
Ensembl chr 1:95,313,033...95,329,354
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:30,545,794...30,553,987
Ensembl chr 6:30,545,794...30,553,987
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:186,410,851...186,421,024
Ensembl chr 2:186,412,291...186,421,026
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:58,036,779...58,098,996
Ensembl chr 3:58,038,042...58,099,363
JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:34,941,445...35,027,460
Ensembl chr15:34,967,477...35,026,828
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:119,572,295...119,597,405
Ensembl chr 8:119,575,868...119,598,108
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:45,189,768...45,255,277
Ensembl chr13:45,189,804...45,255,277
JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:69,073,681...69,194,041
Ensembl chr 7:69,075,562...69,194,102
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197
JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:48,457,102...48,470,444
Ensembl chr12:48,456,932...48,473,154
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:102,953,894...102,962,964
Ensembl chr 1:102,953,918...102,962,964
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:79,478,804...79,608,118
Ensembl chr 5:79,478,912...79,607,052
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:77,920,781...77,939,284
Ensembl chr 1:77,920,783...77,938,574
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:26,544,059...26,576,365
Ensembl chr12:26,544,067...26,576,366
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:68,572,901...68,602,803
Ensembl chr 9:68,572,911...68,602,890
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:126,526,006...126,622,163
Ensembl chr 6:126,526,009...126,614,215
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr 3:99,600,213...99,615,462
Ensembl chr 3:99,600,159...99,615,432
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:14,317,083...14,343,724
Ensembl chr 5:14,316,918...14,347,778
JBrowse link
irigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan multiple interactions ISO irigenin inhibits the reaction [TNF protein results in decreased expression of ACAN mRNA]; irigenin inhibits the reaction [TNF protein results in decreased expression of ACAN protein] CTD PMID:34600870 NCBI chr 1:142,390,951...142,453,779
Ensembl chr 1:142,390,951...142,453,779
JBrowse link
G Casp3 caspase 3 multiple interactions ISO irigenin inhibits the reaction [TNF protein results in increased activity of and results in increased cleavage of CASP3 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of CASP3 mRNA] CTD PMID:34600870 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions ISO irigenin inhibits the reaction [TNF protein results in decreased expression of COL2A1 mRNA]; irigenin inhibits the reaction [TNF protein results in decreased expression of COL2A1 protein] CTD PMID:34600870 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:130,977,561...131,006,627
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO irigenin inhibits the reaction [TNF protein results in increased expression of MMP13 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP13 protein] CTD PMID:34600870 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:12,782,813...12,793,105
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO irigenin inhibits the reaction [TNF protein results in increased expression of MMP2 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP2 protein] CTD PMID:34600870 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO irigenin inhibits the reaction [TNF protein results in increased expression of MMP3 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP3 protein] CTD PMID:34600870 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:12,925,280...12,938,826
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO irigenin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP9 protein] CTD PMID:34600870 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO irigenin inhibits the reaction [TNF protein results in decreased expression of ACAN mRNA]; irigenin inhibits the reaction [TNF protein results in decreased expression of ACAN protein]; irigenin inhibits the reaction [TNF protein results in decreased expression of COL2A1 mRNA]; irigenin inhibits the reaction [TNF protein results in decreased expression of COL2A1 protein]; irigenin inhibits the reaction [TNF protein results in increased activity of and results in increased cleavage of CASP3 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of CASP3 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP13 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP2 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP2 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP3 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP3 protein]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; irigenin inhibits the reaction [TNF protein results in increased expression of MMP9 protein] CTD PMID:34600870 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
Irisflorentin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
increases activity
EXP 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [irisflorentin results in increased activity of ACHE protein] CTD PMID:31034797 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
JBrowse link
prunetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity EXP prunetin results in decreased activity of ALDH2 protein CTD PMID:11142365 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:40,610,224...40,643,219
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B mRNA]; prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein] CTD PMID:23597450 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 multiple interactions ISO prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] CTD PMID:23597450 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:23597450 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
ISO [prunetin results in decreased expression of NOS2 mRNA] inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased chemical synthesis of Nitric Oxide]; prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 protein] CTD PMID:23597450 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
ISO [prunetin results in decreased expression of PTGS2 mRNA] which results in decreased chemical synthesis of Dinoprostone; prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein] CTD PMID:23597450 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; prunetin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein] CTD PMID:23597450 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
tectoridin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of ACADM mRNA] CTD PMID:20637825 NCBI chr 2:245,518,693...245,542,864
Ensembl chr 2:245,518,693...245,542,864
JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of ACOX1 mRNA] CTD PMID:20637825 NCBI chr10:101,905,083...101,930,136
Ensembl chr10:101,905,083...101,930,136
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of CPT1A mRNA] CTD PMID:20637825 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT1 mRNA] CTD PMID:20637825 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:110,098,906...110,115,016
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of DGAT2 mRNA] CTD PMID:20637825 NCBI chr 1:162,866,237...162,896,655
Ensembl chr 1:162,866,237...162,896,566
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions ISO [Xiao-Ke-An results in increased abundance of tectoridin] which results in decreased activity of DPP4 protein CTD PMID:32535096 NCBI chr 3:67,370,794...67,452,422
Ensembl chr 3:67,370,804...67,452,422
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in increased expression of GPAM mRNA] CTD PMID:20637825 NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:264,113,813...264,175,911
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO tectoridin inhibits the reaction [Ethanol results in decreased expression of PPARA mRNA] CTD PMID:20637825 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
tectorigenin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCB11 mRNA; [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCB11 protein CTD PMID:37348807 NCBI chr 3:74,424,620...74,520,646
Ensembl chr 3:74,424,979...74,520,581
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC2 protein CTD PMID:37348807 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of ABCC4 protein CTD PMID:37348807 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
JBrowse link
G Cat catalase multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased activity of CAT protein CTD PMID:37348807 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of CPT1A mRNA] CTD PMID:35390440 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 protein] CTD PMID:35390440 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:24,174,505...24,184,202
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in increased expression of FASN mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of FASN protein] CTD PMID:35390440 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of GCLC protein; tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of GCLC mRNA] CTD PMID:37348807 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of GCLM protein; tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of GCLM mRNA] CTD PMID:37348807 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:213,031,838...213,055,003
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of GPT protein] CTD PMID:37348807 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of HMOX1 protein; tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of HMOX1 mRNA] CTD PMID:37348807 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of NFE2L2 protein; tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NFE2L2 mRNA] CTD PMID:37348807 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in increased expression of NFKB1 mRNA] CTD PMID:35390440 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [tectorigenin co-treated with 1-Naphthylisothiocyanate] results in increased expression of NQO1 protein CTD PMID:37348807 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1H4 protein]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of NR1H4 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of NR1H4 protein] CTD PMID:35390440 PMID:37348807 NCBI chr 7:25,733,471...25,829,440
Ensembl chr 7:25,733,471...25,829,389
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO tectorigenin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of NR1I3 mRNA] CTD PMID:37348807 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
JBrowse link
G Ocln occludin multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of OCLN mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of OCLN protein] CTD PMID:35390440 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of PPARA mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of PPARA protein] CTD PMID:35390440 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of SREBF1 protein] CTD PMID:35390440 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of TJP1 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in decreased expression of TJP1 protein] CTD PMID:35390440 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in increased expression of TLR4 mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of TLR4 protein] CTD PMID:35390440 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO tectorigenin inhibits the reaction [Dietary Fats results in increased expression of TNF mRNA]; tectorigenin inhibits the reaction [Dietary Fats results in increased expression of TNF protein] CTD PMID:35390440 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    chemical entity 20860
      atom 20860
        nonmetal atom 20766
          oxygen atom 20457
            oxygen molecular entity 20457
              organooxygen compound 19806
                ether 17649
                  methoxyisoflavone 318
                    2',5-Dihydroxy-4',7-dimethoxyisoflavone 0
                    2',7-Dihydroxy-4',5'-dimethoxyisoflavone 0
                    2'-Hydroxypiscerythrinetin 0
                    2'-Methoxyformonetin 0
                    2'-hydroxy-3'-methoxygenistein 0
                    2'-hydroxybiochanin A 0
                    3',4'-Dimethoxy-6,7-methylenedioxyisoflavone 0
                    3'-O-methylorobol 0
                    3'-methoxyisoflavones 0
                    3-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxy-8-methyl-4H-chromen-4-one 0
                    4',5-Dihydroxy-3',7-dimethoxyisoflavone 0
                    4'-hydroxy-6,7-dimethoxyisoflavone 0
                    4'-methoxyisoflavones + 213
                    5,7-Dihydroxy-8,4'-dimethoxyisoflavone 0
                    5,7-Dimethoxyisoflavone 0
                    5,7-Trihydroxy-3',4'-dimethoxyisoflavone 0
                    5-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-7-methoxy-8-methyl-4H-chromen-4-one 0
                    5-hydroxy-7-methoxy-3-(3-methoxyphenyl)-8-methyl-4H-chromen-4-one 0
                    5-hydroxy-7-methoxy-4′-O-(3-methylbut-2-enyl) isoflavone 0
                    7,4'-Di-O-methyldaidzein 0
                    7,4'-dihydroxy-3'-methoxyisoflavone 0
                    7,8-Dimethoxy-3',4'-methylenedioxyisoflavone 0
                    7-Geranylformononetin 0
                    7-Methoxy-2-methylisoflavone 0
                    7-O-Methylisolupalbigenin 0
                    7-O-methyl-8-chlorogenistein 0
                    7-hydroxy-5-methoxy-6,8-dimethylisoflavone 0
                    7-methoxyisoflavones + 7
                    Alfalone 0
                    Cabreuvin 0
                    Durlettone 0
                    Fujikinetin methyl ether 0
                    Gancaonin M 0
                    Glabrescione B 0
                    Irisolone methyl ether 0
                    Maduraktermol C 0
                    Maduraktermol I 0
                    Maduraktermol J 0
                    Maduraktermol K 0
                    Maximaisoflavone D 0
                    Maximaisoflavone J 0
                    Retusin 7-Methyl Ether 0
                    Santal 0
                    [4-(5-hydroxy-7-methoxy-8-methyl-4-oxo-4H-chromen-3-yl)-2-methoxyphenyl]oxidanesulfonic acid 0
                    betavulgarin 0
                    bowdichione 0
                    dalpatein 0
                    dihydrofuro-7-O-methylluteone 0
                    glycitein + 105
                    glycitein 4'-O-glucuronide 0
                    glycitein 7-(6-O-acetyl-beta-D-glucoside) 0
                    glycitein 7-O-beta-D-(2'',4'',6''-O-triacetyl)glucopyranoside 0
                    glycitin + 64
                    lmpk12050091 0
                    malonylglycitin 0
                    pierreione A 0
                    pierreione B 0
                    pierreione C 0
                    pierreione D 0
                    piscerythramine 0
                    pisonianone 0
                    tectoridin 8
                    tectorigenin + 28
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic heterocyclic compound 19388
                                  oxacycle 18300
                                    benzopyran 12186
                                      1-benzopyran 11917
                                        isoflavonoid 3903
                                          isoflavones 3883
                                            methoxyisoflavone 318
                                              2',5-Dihydroxy-4',7-dimethoxyisoflavone 0
                                              2',7-Dihydroxy-4',5'-dimethoxyisoflavone 0
                                              2'-Hydroxypiscerythrinetin 0
                                              2'-Methoxyformonetin 0
                                              2'-hydroxy-3'-methoxygenistein 0
                                              2'-hydroxybiochanin A 0
                                              3',4'-Dimethoxy-6,7-methylenedioxyisoflavone 0
                                              3'-O-methylorobol 0
                                              3'-methoxyisoflavones 0
                                              3-(3,4-dimethoxyphenyl)-5-hydroxy-7-methoxy-8-methyl-4H-chromen-4-one 0
                                              4',5-Dihydroxy-3',7-dimethoxyisoflavone 0
                                              4'-hydroxy-6,7-dimethoxyisoflavone 0
                                              4'-methoxyisoflavones + 213
                                              5,7-Dihydroxy-8,4'-dimethoxyisoflavone 0
                                              5,7-Dimethoxyisoflavone 0
                                              5,7-Trihydroxy-3',4'-dimethoxyisoflavone 0
                                              5-hydroxy-3-(4-hydroxy-3-methoxyphenyl)-7-methoxy-8-methyl-4H-chromen-4-one 0
                                              5-hydroxy-7-methoxy-3-(3-methoxyphenyl)-8-methyl-4H-chromen-4-one 0
                                              5-hydroxy-7-methoxy-4′-O-(3-methylbut-2-enyl) isoflavone 0
                                              7,4'-Di-O-methyldaidzein 0
                                              7,4'-dihydroxy-3'-methoxyisoflavone 0
                                              7,8-Dimethoxy-3',4'-methylenedioxyisoflavone 0
                                              7-Geranylformononetin 0
                                              7-Methoxy-2-methylisoflavone 0
                                              7-O-Methylisolupalbigenin 0
                                              7-O-methyl-8-chlorogenistein 0
                                              7-hydroxy-5-methoxy-6,8-dimethylisoflavone 0
                                              7-methoxyisoflavones + 7
                                              Alfalone 0
                                              Cabreuvin 0
                                              Durlettone 0
                                              Fujikinetin methyl ether 0
                                              Gancaonin M 0
                                              Glabrescione B 0
                                              Irisolone methyl ether 0
                                              Maduraktermol C 0
                                              Maduraktermol I 0
                                              Maduraktermol J 0
                                              Maduraktermol K 0
                                              Maximaisoflavone D 0
                                              Maximaisoflavone J 0
                                              Retusin 7-Methyl Ether 0
                                              Santal 0
                                              [4-(5-hydroxy-7-methoxy-8-methyl-4-oxo-4H-chromen-3-yl)-2-methoxyphenyl]oxidanesulfonic acid 0
                                              betavulgarin 0
                                              bowdichione 0
                                              dalpatein 0
                                              dihydrofuro-7-O-methylluteone 0
                                              glycitein + 105
                                              glycitein 4'-O-glucuronide 0
                                              glycitein 7-(6-O-acetyl-beta-D-glucoside) 0
                                              glycitein 7-O-beta-D-(2'',4'',6''-O-triacetyl)glucopyranoside 0
                                              glycitin + 64
                                              lmpk12050091 0
                                              malonylglycitin 0
                                              pierreione A 0
                                              pierreione B 0
                                              pierreione C 0
                                              pierreione D 0
                                              piscerythramine 0
                                              pisonianone 0
                                              tectoridin 8
                                              tectorigenin + 28
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