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G |
Ache |
acetylcholinesterase |
multiple interactions decreases activity |
ISO EXP |
[Methyl Parathion co-treated with decamethrin] results in decreased activity of ACHE protein; [Methyl Parathion co-treated with Parathion] results in decreased activity of ACHE protein Methyl Parathion results in decreased activity of ACHE protein [Methyl Parathion co-treated with Chlorpyrifos] results in decreased activity of ACHE protein; [Methyl Parathion co-treated with NADP] results in decreased activity of ACHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of ACHE protein; [Methyl Parathion co-treated with pralidoxime] results in decreased expression of ACHE protein; Atropine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; CYP2B1 protein affects the reaction [Methyl Parathion results in decreased activity of ACHE protein]; CYP2B2 protein affects the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Glutathione inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Memantine inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein]; Phenobarbital inhibits the reaction [Methyl Parathion results in decreased activity of ACHE protein] |
CTD |
PMID:1455421 PMID:1512808 PMID:2241428 PMID:3247000 PMID:3975908 PMID:6483827 PMID:7322183 PMID:7966439 PMID:9588345 PMID:10918524 PMID:11405414 PMID:11481665 PMID:11495289 PMID:11684353 PMID:12191869 PMID:12478623 PMID:14514956 PMID:14746346 PMID:15342957 PMID:15591769 PMID:15793557 PMID:16645783 PMID:16766477 PMID:17963125 PMID:19784758 PMID:20100039 PMID:29540303 PMID:32294493 More...
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NCBI chr12:25,042,882...25,050,608
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G |
Add3 |
adducin 3 |
decreases expression affects expression increases expression |
EXP |
Methyl Parathion results in decreased expression of ADD3 mRNA Methyl Parathion affects the expression of ADD3 mRNA Methyl Parathion results in increased expression of ADD3 mRNA |
CTD |
PMID:19784758 |
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NCBI chr 1:262,152,722...262,260,504
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G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
increases activity multiple interactions increases expression |
ISO |
Methyl Parathion results in increased activity of AKR1C1 protein AKR1C1 protein affects the susceptibility to [Benzo(a)pyrene co-treated with Methyl Parathion]; Benzo(a)pyrene promotes the reaction [Methyl Parathion results in increased activity of AKR1C1 protein]; Methyl Parathion promotes the reaction [Benzo(a)pyrene results in increased expression of AKR1C1 mRNA] Methyl Parathion results in increased expression of AKR1C1 mRNA |
CTD |
PMID:19800895 |
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NCBI chr17:70,720,397...70,747,285
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
multiple interactions increases activity increases expression |
ISO |
AKR1C2 protein affects the susceptibility to [Benzo(a)pyrene co-treated with Methyl Parathion]; Benzo(a)pyrene promotes the reaction [Methyl Parathion results in increased activity of AKR1C2 protein]; Methyl Parathion promotes the reaction [Benzo(a)pyrene results in increased expression of AKR1C2 mRNA] Methyl Parathion results in increased expression of AKR1C2 mRNA |
CTD |
PMID:19800895 |
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NCBI chr17:70,669,684...70,717,935
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G |
Alb |
albumin |
affects binding |
ISO |
Methyl Parathion binds to ALB protein |
CTD |
PMID:14700528 |
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NCBI chr14:17,891,564...17,907,043
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G |
Ar |
androgen receptor |
multiple interactions affects binding |
ISO EXP |
Dihydrotestosterone inhibits the reaction [Methyl Parathion results in increased activity of AR protein]; Methyl Parathion inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; Methyl Parathion inhibits the reaction [Metribolone results in increased activity of AR protein] Methyl Parathion binds to AR protein |
CTD |
PMID:14565775 PMID:15064155 PMID:18324785 PMID:33049310 |
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NCBI chr X:63,104,771...63,273,934
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G |
Bax |
BCL2 associated X, apoptosis regulator |
decreases expression |
EXP |
Methyl Parathion results in decreased expression of BAX mRNA |
CTD |
PMID:29319433 |
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NCBI chr 1:105,076,472...105,081,906
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G |
Bche |
butyrylcholinesterase |
multiple interactions decreases activity |
ISO EXP |
[Methyl Parathion co-treated with Parathion] results in decreased activity of BCHE protein [Methyl Parathion co-treated with Chlorpyrifos] results in decreased activity of BCHE protein; [Methyl Parathion co-treated with Diazinon] results in decreased activity of BCHE protein; [Methyl Parathion co-treated with pralidoxime co-treated with Atropine] results in decreased expression of BCHE protein; [Methyl Parathion co-treated with pralidoxime] results in decreased expression of BCHE protein Methyl Parathion results in decreased activity of BCHE protein |
CTD |
PMID:1512808 PMID:11405414 PMID:11481665 PMID:17963125 |
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NCBI chr 2:160,607,289...160,699,760
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G |
Bdnf |
brain-derived neurotrophic factor |
increases expression |
EXP |
Methyl Parathion results in increased expression of BDNF mRNA; Methyl Parathion results in increased expression of BDNF protein |
CTD |
PMID:17893397 |
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NCBI chr 3:116,619,633...116,670,212
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G |
Casp3 |
caspase 3 |
increases activity |
EXP |
Methyl Parathion results in increased activity of CASP3 protein |
CTD |
PMID:27941166 |
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NCBI chr16:52,395,539...52,413,794
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G |
Casp9 |
caspase 9 |
increases activity |
EXP |
Methyl Parathion results in increased activity of CASP9 protein |
CTD |
PMID:27941166 |
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G |
Cat |
catalase |
increases activity |
EXP |
Methyl Parathion results in increased activity of CAT protein |
CTD |
PMID:3975908 |
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NCBI chr 3:110,297,340...110,329,526
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G |
Cck |
cholecystokinin |
affects expression decreases expression increases expression |
EXP |
Methyl Parathion affects the expression of CCK mRNA Methyl Parathion results in decreased expression of CCK mRNA Methyl Parathion results in increased expression of CCK mRNA |
CTD |
PMID:19784758 |
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NCBI chr 8:121,153,499...121,160,194
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Methyl Parathion results in increased expression of CDKN1A mRNA |
CTD |
PMID:18418871 |
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NCBI chr20:7,150,820...7,161,373
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G |
Chrm1 |
cholinergic receptor, muscarinic 1 |
decreases activity decreases expression |
EXP |
Methyl Parathion results in decreased activity of CHRM1 protein Methyl Parathion results in decreased expression of CHRM1 protein |
CTD |
PMID:14746346 PMID:16645783 PMID:17666426 PMID:18650256 PMID:30035273 |
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NCBI chr 1:205,567,226...205,583,001
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G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
decreases activity decreases expression |
EXP |
Methyl Parathion results in decreased activity of CHRM2 protein Methyl Parathion results in decreased expression of CHRM2 protein |
CTD |
PMID:14746346 PMID:16645783 PMID:17666426 PMID:18650256 |
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NCBI chr 4:65,981,136...66,116,128
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G |
Chrm3 |
cholinergic receptor, muscarinic 3 |
decreases activity decreases expression |
EXP |
Methyl Parathion results in decreased activity of CHRM3 protein Methyl Parathion results in decreased expression of CHRM3 protein |
CTD |
PMID:17666426 PMID:30035273 |
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NCBI chr17:64,696,549...65,158,622
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G |
Chrm4 |
cholinergic receptor, muscarinic 4 |
decreases activity |
EXP |
Methyl Parathion results in decreased activity of CHRM4 protein |
CTD |
PMID:17666426 |
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NCBI chr 3:98,349,080...98,356,821
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G |
Chrna6 |
cholinergic receptor nicotinic alpha 6 subunit |
increases expression |
EXP |
Methyl Parathion results in increased expression of CHRNA6 mRNA |
CTD |
PMID:18977431 |
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NCBI chr16:64,697,741...64,704,441
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G |
Chrna7 |
cholinergic receptor nicotinic alpha 7 subunit |
affects expression |
EXP |
Methyl Parathion affects the expression of CHRNA7 mRNA |
CTD |
PMID:18977431 |
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NCBI chr 1:126,123,425...126,249,181
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
increases activity |
ISO |
Methyl Parathion results in increased activity of CYP19A1 protein |
CTD |
PMID:16996190 |
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NCBI chr 8:63,449,148...63,476,534
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO |
Methyl Parathion results in increased expression of CYP1A1 mRNA Methyl Parathion inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:19800895 |
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NCBI chr 8:66,991,940...66,998,014
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
CYP2B1 protein affects the reaction [Methyl Parathion results in decreased activity of ACHE protein] |
CTD |
PMID:11684353 |
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NCBI chr 1:90,646,098...90,669,762
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G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
multiple interactions |
EXP |
CYP2B2 protein affects the reaction [Methyl Parathion results in decreased activity of ACHE protein] |
CTD |
PMID:11684353 |
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NCBI chr 1:90,722,243...90,736,272
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
increases metabolic processing |
EXP |
CYP2C11 protein results in increased metabolism of Methyl Parathion |
CTD |
PMID:22271348 |
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NCBI chr 1:246,175,216...246,211,445
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G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
increases metabolic processing |
EXP |
CYP3A23-3A1 protein results in increased metabolism of Methyl Parathion |
CTD |
PMID:22271348 |
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NCBI chr12:14,369,950...14,398,803
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
Methyl Parathion binds to and results in increased activity of ESR1 protein |
CTD |
PMID:33049310 |
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NCBI chr 1:43,511,685...43,904,454
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
Methyl Parathion binds to and results in increased activity of ESR2 protein |
CTD |
PMID:33049310 |
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NCBI chr 6:100,589,553...100,645,240
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Methyl Parathion results in increased expression of FOS mRNA |
CTD |
PMID:17893397 |
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NCBI chr 6:110,852,188...110,855,054
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G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
increases expression |
EXP |
Methyl Parathion results in increased expression of GABBR2 mRNA |
CTD |
PMID:19784758 |
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NCBI chr 5:60,947,517...61,288,104
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G |
Gabrr2 |
gamma-aminobutyric acid type A receptor subunit rho 2 |
increases expression |
EXP |
Methyl Parathion results in increased expression of GABRR2 mRNA |
CTD |
PMID:19784758 |
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NCBI chr 5:47,445,280...47,489,929
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Methyl Parathion results in increased expression of GADD45A mRNA |
CTD |
PMID:18418871 |
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NCBI chr 4:97,484,497...97,486,799
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G |
Gp1bb |
glycoprotein Ib platelet subunit beta |
increases expression |
EXP |
Methyl Parathion results in increased expression of GP1BB mRNA |
CTD |
PMID:19784758 |
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NCBI chr11:82,378,216...82,379,393
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G |
Gpt |
glutamic--pyruvic transaminase |
increases activity multiple interactions |
EXP |
Methyl Parathion results in increased activity of GPT protein Glutathione inhibits the reaction [Methyl Parathion results in increased activity of GPT protein] |
CTD |
PMID:20100039 |
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NCBI chr 7:110,295,599...110,300,134
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G |
Gsr |
glutathione-disulfide reductase |
affects expression |
EXP |
Methyl Parathion affects the expression of GSR protein |
CTD |
PMID:18571824 |
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NCBI chr16:65,185,574...65,228,742
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions increases expression |
ISO |
GSTA1 protein affects the metabolism of and results in decreased alkylation of Methyl Parathion Methyl Parathion results in increased expression of GSTA1 mRNA; Methyl Parathion results in increased expression of GSTA1 protein |
CTD |
PMID:15103050 PMID:21907274 |
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NCBI chr 9:23,703,476...23,720,121
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G |
Gstt1 |
glutathione S-transferase theta 1 |
multiple interactions |
ISO |
GSTT1 protein affects the metabolism of and results in decreased alkylation of Methyl Parathion |
CTD |
PMID:15103050 |
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NCBI chr20:12,856,068...12,873,020
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G |
Gusb |
glucuronidase, beta |
decreases activity |
EXP |
Methyl Parathion results in decreased activity of GUSB protein |
CTD |
PMID:3008131 PMID:3008132 |
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NCBI chr12:32,337,281...32,350,838
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G |
Il1b |
interleukin 1 beta |
increases expression |
ISO |
Methyl Parathion results in increased expression of IL1B mRNA |
CTD |
PMID:26948828 |
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NCBI chr 3:137,030,200...137,036,581
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G |
Il6 |
interleukin 6 |
increases expression |
ISO |
Methyl Parathion results in increased expression of IL6 mRNA |
CTD |
PMID:26948828 |
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NCBI chr 4:5,889,999...5,894,575
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G |
Lcat |
lecithin cholesterol acyltransferase |
decreases activity multiple interactions |
ISO |
Methyl Parathion results in decreased activity of LCAT protein Methyl Parathion inhibits the reaction [[LCAT protein results in increased metabolism of Lecithins] which results in increased chemical synthesis of Cholesterol Esters] |
CTD |
PMID:4847537 |
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NCBI chr19:33,834,748...33,838,214
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G |
Maoa |
monoamine oxidase A |
increases activity |
EXP |
Methyl Parathion results in increased activity of MAOA protein |
CTD |
PMID:11495289 |
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NCBI chr X:8,615,239...8,681,372
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G |
Mdm2 |
MDM2 proto-oncogene |
increases expression |
ISO |
Methyl Parathion results in increased expression of MDM2 mRNA |
CTD |
PMID:18418871 |
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NCBI chr 7:55,176,558...55,201,757
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G |
Mki67 |
marker of proliferation Ki-67 |
decreases expression |
ISO |
Methyl Parathion results in decreased expression of MKI67 protein |
CTD |
PMID:18418871 |
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NCBI chr 1:199,926,150...199,952,847
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases methylation |
ISO |
Methyl Parathion results in increased methylation of NFE2L2 promoter |
CTD |
PMID:29540303 |
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NCBI chr 3:81,001,529...81,031,165
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G |
Ngf |
nerve growth factor |
affects expression |
EXP |
Methyl Parathion affects the expression of NGF mRNA; Methyl Parathion affects the expression of NGF protein |
CTD |
PMID:17893397 |
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NCBI chr 2:192,589,580...192,642,971
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
Methyl Parathion binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:33049310 |
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NCBI chr11:75,965,717...76,006,733
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G |
Ogg1 |
8-oxoguanine DNA glycosylase |
increases methylation |
ISO |
Methyl Parathion results in increased methylation of OGG1 promoter |
CTD |
PMID:29540303 |
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NCBI chr 4:148,030,237...148,037,599
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G |
P2rx1 |
purinergic receptor P2X 1 |
increases expression |
EXP |
Methyl Parathion results in increased expression of P2RX1 mRNA |
CTD |
PMID:19784758 |
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NCBI chr10:57,618,586...57,633,648
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases expression |
ISO |
Methyl Parathion results in decreased expression of and results in decreased activity of PON1 protein Methyl Parathion results in decreased expression of PON1 mRNA |
CTD |
PMID:26948828 |
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NCBI chr 4:34,261,312...34,292,327
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
Methyl Parathion binds to and results in increased activity of PPARG protein |
CTD |
PMID:33049310 |
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NCBI chr 4:150,095,743...150,221,104
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
decreases expression |
ISO |
Methyl Parathion results in decreased expression of RIPK1 mRNA |
CTD |
PMID:26688254 |
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NCBI chr17:31,044,983...31,077,167
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G |
Srsf5 |
serine and arginine rich splicing factor 5 |
decreases expression affects expression increases expression |
EXP |
Methyl Parathion results in decreased expression of SRSF5 mRNA Methyl Parathion affects the expression of SRSF5 mRNA Methyl Parathion results in increased expression of SRSF5 mRNA |
CTD |
PMID:19784758 |
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NCBI chr 6:100,605,165...100,610,192
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G |
St14 |
ST14 transmembrane serine protease matriptase |
affects expression decreases expression increases expression |
EXP |
Methyl Parathion affects the expression of ST14 mRNA Methyl Parathion results in decreased expression of ST14 mRNA Methyl Parathion results in increased expression of ST14 mRNA |
CTD |
PMID:19784758 |
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NCBI chr 8:29,540,805...29,581,704
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G |
Tgm1 |
transglutaminase 1 |
decreases expression |
EXP |
Methyl Parathion results in decreased expression of TGM1 mRNA |
CTD |
PMID:19784758 |
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NCBI chr15:29,191,039...29,206,000
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G |
Timp3 |
TIMP metallopeptidase inhibitor 3 |
increases expression affects expression |
EXP |
Methyl Parathion results in increased expression of TIMP3 mRNA Methyl Parathion affects the expression of TIMP3 mRNA |
CTD |
PMID:19784758 |
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NCBI chr 7:19,408,539...19,459,558
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G |
Tnf |
tumor necrosis factor |
increases expression decreases expression |
ISO EXP |
Methyl Parathion results in increased expression of TNF mRNA Methyl Parathion results in decreased expression of TNF mRNA |
CTD |
PMID:26948828 PMID:29319433 |
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NCBI chr20:3,626,685...3,629,303
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G |
Tp53 |
tumor protein p53 |
increases expression affects activity |
ISO |
Methyl Parathion results in increased expression of TP53 mRNA Methyl Parathion metabolite affects the activity of TP53 protein |
CTD |
PMID:18418871 PMID:35435491 |
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NCBI chr10:54,798,871...54,810,300
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