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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoflavanones
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Accession:CHEBI:38741 term browser browse the term
Definition:Members of the class of isoflavans that have a 3,4-dihydro-3-aryl-2H-1-benzopyran-4-one skeleton and its substituted derivatives.
Synonyms:related_synonym: Formula=C15O2R12;   SMILES=[*]c1c([*])c([*])c(c([*])c1[*])C1([*])C(=O)c2c([*])c([*])c([*])c([*])c2OC1([*])[*]


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alpinumisoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein affects localization ISO alpinumisoflavone affects the localization of BAX protein CTD PMID:23850732 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO alpinumisoflavone results in decreased expression of BCL2 protein CTD PMID:23850732 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO alpinumisoflavone results in decreased expression of BID protein CTD PMID:23850732 NCBI chr 6:120,893,119...120,917,062
Ensembl chr 6:120,891,930...120,916,853
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO [alpinumisoflavone results in increased expression of FAS protein] which results in increased cleavage of CASP3 protein
alpinumisoflavone results in increased cleavage of CASP3 protein
CTD PMID:23850732 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 increases cleavage
multiple interactions
ISO alpinumisoflavone results in increased cleavage of CASP9 protein
[alpinumisoflavone results in increased expression of FAS protein] which results in increased cleavage of CASP9 protein
CTD PMID:23850732 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase decreases expression ISO alpinumisoflavone results in decreased expression of CHUK protein CTD PMID:23850732 NCBI chr19:44,073,334...44,107,505
Ensembl chr19:44,073,335...44,107,480
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO alpinumisoflavone affects the localization of CYCS protein CTD PMID:23850732 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) multiple interactions
increases expression
ISO [alpinumisoflavone results in increased expression of FAS protein] which results in increased cleavage of CASP3 protein; [alpinumisoflavone results in increased expression of FAS protein] which results in increased cleavage of CASP9 protein CTD PMID:23850732 NCBI chr19:34,290,647...34,327,775
Ensembl chr19:34,290,666...34,327,772
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions ISO alpinumisoflavone inhibits the reaction [1,10-phenanthroline deficiency results in increased activity of HIF1A protein]; alpinumisoflavone inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein] CTD PMID:19091749 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO alpinumisoflavone results in increased cleavage of PARP1 protein CTD PMID:23850732 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) decreases expression ISO alpinumisoflavone results in decreased expression of RELA protein CTD PMID:23850732 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO alpinumisoflavone results in decreased phosphorylation of and results in decreased activity of STAT3 protein CTD PMID:23850732 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions ISO alpinumisoflavone results in decreased phosphorylation of and results in decreased activity of STAT5A protein CTD PMID:23850732 NCBI chr11:100,859,351...100,885,169
Ensembl chr11:100,859,351...100,885,169
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions ISO alpinumisoflavone results in decreased phosphorylation of and results in decreased activity of STAT6 protein CTD PMID:23850732 NCBI chr10:127,642,955...127,660,987
Ensembl chr10:127,642,986...127,660,957
JBrowse link
cajanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein multiple interactions
increases expression
ISO [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP3 protein; [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP9 protein; [[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein CTD PMID:20638373 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
ISO cajanol results in decreased expression of BCL2 protein
[[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP3 protein; [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP9 protein; [[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein
CTD PMID:20638373 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP3 protein
cajanol results in increased activity of CASP3 protein
CTD PMID:20638373 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP9 protein
cajanol results in increased activity of CASP9 protein
CTD PMID:20638373 NCBI chr 4:141,793,612...141,815,978
Ensembl chr 4:141,793,612...141,815,976
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
ISO cajanol affects the localization of CYCS protein
[[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP3 protein; [[[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein] which results in increased activity of CASP9 protein; [[cajanol results in decreased expression of BCL2 protein] co-treated with [cajanol results in increased expression of BAX protein]] affects the localization of CYCS protein
CTD PMID:20638373 NCBI chr 6:50,562,563...50,566,569
Ensembl chr 6:50,562,563...50,566,538
JBrowse link
Deguelin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ADM mRNA] CTD PMID:22745725 NCBI chr 7:110,627,657...110,629,820
Ensembl chr 7:110,627,661...110,629,820
JBrowse link
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 multiple interactions ISO deguelin results in increased expression of and affects the localization of AIFM1 protein CTD PMID:26592500 NCBI chr  X:48,474,944...48,513,563
Ensembl chr  X:48,474,944...48,513,563
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases expression
affects phosphorylation
increases phosphorylation
multiple interactions
decreases phosphorylation
ISO
EXP
deguelin metabolite results in decreased expression of AKT1 protein; deguelin results in decreased expression of AKT1 protein
deguelin affects the phosphorylation of AKT1 protein
deguelin results in increased phosphorylation of AKT1 protein
deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]
deguelin results in decreased phosphorylation of AKT1 protein
CTD PMID:16288123 PMID:17015749 PMID:18593368 PMID:19139008 PMID:19336726 PMID:19901985 PMID:25322282 PMID:29512685 NCBI chr12:112,653,821...112,674,884
Ensembl chr12:112,653,821...112,674,884
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ANGPTL4 mRNA] CTD PMID:22745725 NCBI chr17:33,774,900...33,781,575
Ensembl chr17:33,773,750...33,781,830
JBrowse link
G Ar androgen receptor multiple interactions ISO deguelin results in decreased expression of and affects the localization of AR protein CTD PMID:27255535 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Atm ataxia telangiectasia mutated decreases expression ISO deguelin results in decreased expression of ATM mRNA CTD PMID:22227970 NCBI chr 9:53,437,122...53,536,828
Ensembl chr 9:53,439,149...53,536,740
JBrowse link
G Atr ataxia telangiectasia and Rad3 related decreases expression ISO deguelin results in decreased expression of ATR mRNA CTD PMID:22227970 NCBI chr 9:95,857,597...95,953,217
Ensembl chr 9:95,857,597...95,951,781
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO deguelin results in increased expression of BAK1 protein CTD PMID:26592500 NCBI chr17:27,019,812...27,028,627
Ensembl chr17:27,019,810...27,029,009
JBrowse link
G Bax BCL2-associated X protein increases expression ISO deguelin results in increased expression of BAX mRNA; deguelin results in increased expression of BAX protein CTD PMID:26592500 PMID:29512685 NCBI chr 7:45,461,695...45,466,903
Ensembl chr 7:45,461,697...45,466,898
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
ISO deguelin results in decreased expression of BCL2 mRNA; deguelin results in decreased expression of BCL2 protein
deguelin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]
CTD PMID:19365708 PMID:22623043 PMID:26592500 PMID:29512685 NCBI chr 1:106,538,176...106,714,290
Ensembl chr 1:106,538,178...106,714,274
JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions
decreases expression
ISO deguelin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]
deguelin results in decreased expression of BCL2L1 mRNA; deguelin results in decreased expression of BCL2L1 protein
CTD PMID:19365708 PMID:21472727 PMID:22623043 PMID:26592500 NCBI chr 2:152,758,732...152,833,803
Ensembl chr 2:152,780,668...152,831,728
JBrowse link
G Bdnf brain derived neurotrophic factor multiple interactions EXP deguelin inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein] CTD PMID:17209049 NCBI chr 2:109,674,700...109,727,043
Ensembl chr 2:109,674,700...109,727,007
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression
ISO deguelin inhibits the reaction [docetaxel results in increased expression of BIRC5 protein]; deguelin inhibits the reaction [Doxorubicin results in increased expression of BIRC5 protein]
deguelin results in decreased expression of BIRC5 protein
CTD PMID:17035597 PMID:18593368 PMID:21472727 NCBI chr11:117,849,237...117,855,743
Ensembl chr11:117,849,251...117,855,743
JBrowse link
G Brca1 breast cancer 1, early onset decreases expression ISO deguelin results in decreased expression of BRCA1 mRNA CTD PMID:22227970 NCBI chr11:101,488,761...101,551,955
Ensembl chr11:101,488,764...101,551,955
JBrowse link
G Car9 carbonic anhydrase 9 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of CA9 mRNA] CTD PMID:22745725 NCBI chr 4:43,507,026...43,513,729
Ensembl chr 4:43,506,966...43,513,729
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases activity
ISO deguelin results in increased cleavage of CASP3 protein
[NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of CASP3 protein
deguelin results in increased activity of CASP3 protein
CTD PMID:18593368 PMID:19336726 PMID:22623043 PMID:22986522 PMID:25242579 PMID:26592500 NCBI chr 8:46,617,291...46,639,698
Ensembl chr 8:46,617,291...46,639,689
JBrowse link
G Casp6 caspase 6 multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP6 protein CTD PMID:25242579 NCBI chr 3:129,901,415...129,914,112
Ensembl chr 3:129,901,425...129,914,103
JBrowse link
G Casp7 caspase 7 increases expression ISO deguelin metabolite results in increased expression of CASP7 protein modified form; deguelin results in increased expression of CASP7 protein modified form CTD PMID:19139008 NCBI chr19:56,396,833...56,442,348
Ensembl chr19:56,397,129...56,442,344
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP8 protein CTD PMID:25242579 NCBI chr 1:58,795,233...58,847,503
Ensembl chr 1:58,795,374...58,847,503
JBrowse link
G Ccl2 chemokine (C-C motif) ligand 2 multiple interactions ISO deguelin promotes the reaction [Oxygen deficiency results in increased expression of CCL2 mRNA] CTD PMID:22745725 NCBI chr11:82,035,577...82,037,452
Ensembl chr11:82,035,571...82,037,453
JBrowse link
G Ccl5 chemokine (C-C motif) ligand 5 multiple interactions ISO deguelin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:28529457 NCBI chr11:83,525,778...83,530,518
Ensembl chr11:83,525,778...83,530,518
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of CCND1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CCND1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of CCND1 protein] CTD PMID:15960896 PMID:17015749 PMID:19861542 PMID:21472727 NCBI chr 7:144,929,931...144,939,831
Ensembl chr 7:144,929,931...144,939,925
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO deguelin results in decreased expression of CCNE1 mRNA CTD PMID:29512685 NCBI chr 7:38,097,984...38,107,490
Ensembl chr 7:38,097,984...38,107,534
JBrowse link
G Cd14 CD14 antigen multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of CD14 protein CTD PMID:25242579 NCBI chr18:36,725,064...36,726,815
Ensembl chr18:36,725,067...36,726,798
JBrowse link
G Cd163 CD163 antigen multiple interactions ISO [deguelin co-treated with Oxygen deficiency] results in increased expression of CD163 mRNA CTD PMID:22745725 NCBI chr 6:124,304,636...124,330,529
Ensembl chr 6:124,304,656...124,330,527
JBrowse link
G Cd44 CD44 antigen decreases expression ISO deguelin results in decreased expression of CD44 mRNA; deguelin results in decreased expression of CD44 protein CTD PMID:26884827 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665
JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions
affects localization
ISO deguelin results in increased expression of CDH1 mRNA; deguelin results in increased expression of CDH1 protein
deguelin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; deguelin promotes the reaction [CTNNB1 protein binds to CDH1 protein]
deguelin affects the localization of CDH1 protein
CTD PMID:22986522 PMID:28509438 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO deguelin results in decreased expression of CDH2 protein CTD PMID:22986522 NCBI chr18:16,588,877...16,809,246
Ensembl chr18:16,588,877...16,809,246
JBrowse link
G Cdh3 cadherin 3 increases expression ISO deguelin results in increased expression of CDH3 mRNA CTD PMID:19861542 NCBI chr 8:106,510,852...106,556,911
Ensembl chr 8:106,510,891...106,557,297
JBrowse link
G Cdh7 cadherin 7, type 2 increases expression ISO deguelin results in increased expression of CDH7 mRNA CTD PMID:19861542 NCBI chr 1:109,982,237...110,145,272
Ensembl chr 1:109,982,431...110,140,157
JBrowse link
G Cdh9 cadherin 9 increases expression ISO deguelin results in increased expression of CDH9 mRNA CTD PMID:19861542 NCBI chr15:16,728,550...16,857,138
Ensembl chr15:16,728,756...16,857,094
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO deguelin metabolite results in decreased expression of CDK4 protein; deguelin results in decreased expression of CDK4 protein CTD PMID:19139008 PMID:19336726 NCBI chr10:127,063,535...127,067,288
Ensembl chr10:127,063,534...127,067,920
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) decreases expression
increases expression
ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CDKN1A protein; deguelin metabolite results in decreased expression of CDKN1A protein; deguelin results in decreased expression of CDKN1A protein
deguelin results in increased expression of CDKN1A mRNA
CTD PMID:19139008 PMID:25242579 PMID:29512685 NCBI chr17:29,090,979...29,100,722
Ensembl chr17:29,090,976...29,100,727
JBrowse link
G Cebpa CCAAT/enhancer binding protein (C/EBP), alpha decreases expression ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CEBPA protein CTD PMID:25242579 NCBI chr 7:35,119,293...35,121,928
Ensembl chr 7:35,119,293...35,121,928
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
decreases expression
ISO deguelin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]
deguelin results in decreased expression of CFLAR mRNA
CTD PMID:22623043 NCBI chr 1:58,711,311...58,758,884
Ensembl chr 1:58,711,508...58,758,884
JBrowse link
G Cldn2 claudin 2 increases expression ISO deguelin results in increased expression of CLDN2 mRNA CTD PMID:19861542 NCBI chr  X:139,800,808...139,811,386
Ensembl chr  X:139,800,828...139,811,386
JBrowse link
G Cldn5 claudin 5 increases expression ISO deguelin results in increased expression of CLDN5 mRNA CTD PMID:19861542 NCBI chr16:18,776,847...18,778,262
Ensembl chr16:18,776,847...18,778,262
JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 multiple interactions
decreases expression
increases degradation
ISO [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of CCND1 protein; [deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of MYC protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of CTNNB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of CTNNB1 protein]; deguelin promotes the reaction [CTNNB1 protein binds to CDH1 protein] CTD PMID:21472727 PMID:22986522 NCBI chr 9:120,933,400...120,960,507
Ensembl chr 9:120,929,216...120,960,507
JBrowse link
G Cxcl15 chemokine (C-X-C motif) ligand 15 multiple interactions ISO deguelin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] CTD PMID:22623043 NCBI chr 5:90,794,534...90,803,067
Ensembl chr 5:90,794,534...90,803,067
JBrowse link
G Cxcr4 chemokine (C-X-C motif) receptor 4 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of CXCR4 mRNA] CTD PMID:22745725 NCBI chr 1:128,588,199...128,592,299
Ensembl chr 1:128,588,199...128,592,293
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions EXP deguelin inhibits the reaction [1-nitropyrene results in increased stability of CYP1A1 mRNA] CTD PMID:19961161 NCBI chr 9:57,687,928...57,703,824
Ensembl chr 9:57,687,928...57,703,824
JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 decreases expression ISO deguelin results in decreased expression of DKK2 mRNA CTD PMID:19861542 NCBI chr 3:132,085,266...132,180,304
Ensembl chr 3:132,085,292...132,180,304
JBrowse link
G Dkk4 dickkopf WNT signaling pathway inhibitor 4 increases expression ISO deguelin results in increased expression of DKK4 mRNA CTD PMID:19861542 NCBI chr 8:22,623,685...22,628,018
Ensembl chr 8:22,624,043...22,627,547
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO deguelin metabolite results in decreased expression of EGFR protein; deguelin results in decreased expression of EGFR protein CTD PMID:19139008 NCBI chr11:16,752,203...16,913,907
Ensembl chr11:16,752,203...16,918,158
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of EGLN3 mRNA] CTD PMID:22745725 NCBI chr12:54,178,981...54,203,874
Ensembl chr12:54,178,981...54,203,860
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation ISO deguelin results in increased phosphorylation of EIF2AK3 protein CTD PMID:25322282 NCBI chr 6:70,844,484...70,905,241
Ensembl chr 6:70,844,515...70,905,245
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of EIF4EBP1 protein modified form; deguelin results in decreased expression of EIF4EBP1 protein modified form
deguelin results in decreased phosphorylation of EIF4EBP1 protein
CTD PMID:19139008 PMID:27255535 NCBI chr 8:27,260,327...27,275,656
Ensembl chr 8:27,260,329...27,276,674
JBrowse link
G Eno2 enolase 2, gamma neuronal decreases secretion ISO deguelin results in decreased secretion of ENO2 protein CTD PMID:26884827 NCBI chr 6:124,760,053...124,769,673
Ensembl chr 6:124,760,053...124,769,673
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ENTPD1 protein] CTD PMID:27899277 NCBI chr19:40,612,366...40,741,602
Ensembl chr19:40,612,366...40,741,602
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression ISO deguelin results in decreased expression of EPAS1 protein CTD PMID:19336726 NCBI chr17:86,753,864...86,833,410
Ensembl chr17:86,753,700...86,833,410
JBrowse link
G Ern1 endoplasmic reticulum (ER) to nucleus signalling 1 decreases expression ISO deguelin results in decreased expression of ERN1 protein CTD PMID:25322282 NCBI chr11:106,397,620...106,487,796
Ensembl chr11:106,394,650...106,487,852
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions EXP deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] CTD PMID:9270009 NCBI chr12:85,473,890...85,477,274
Ensembl chr12:85,473,890...85,477,273
JBrowse link
G Frzb frizzled-related protein increases expression ISO deguelin results in increased expression of FRZB mRNA CTD PMID:19861542 NCBI chr 2:80,411,970...80,447,396
Ensembl chr 2:80,411,970...80,447,625
JBrowse link
G Fzd10 frizzled class receptor 10 increases expression ISO deguelin results in increased expression of FZD10 mRNA CTD PMID:19861542 NCBI chr 5:128,601,106...128,604,093
Ensembl chr 5:128,600,844...128,604,093
JBrowse link
G Fzd4 frizzled class receptor 4 increases expression ISO deguelin results in increased expression of FZD4 mRNA CTD PMID:19861542 NCBI chr 7:89,404,366...89,410,110
Ensembl chr 7:89,404,355...89,413,134
JBrowse link
G Fzd8 frizzled class receptor 8 increases expression ISO deguelin results in increased expression of FZD8 mRNA CTD PMID:19861542 NCBI chr18:9,212,856...9,216,201
Ensembl chr18:9,212,163...9,218,136
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO deguelin results in decreased phosphorylation of GSK3B protein CTD PMID:19336726 PMID:21472727 NCBI chr16:38,089,001...38,246,084
Ensembl chr16:38,089,001...38,246,084
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases degradation
multiple interactions
ISO deguelin results in increased degradation of HIF1A protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in increased degradation of HIF1A protein]; deguelin inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; deguelin metabolite inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]
CTD PMID:17764071 PMID:18575727 PMID:19139008 PMID:22745725 PMID:27899277 NCBI chr12:73,901,324...73,947,554
Ensembl chr12:73,901,375...73,947,530
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ICAM1 mRNA]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of ICAM1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:17015749 PMID:22745725 NCBI chr 9:21,015,940...21,028,814
Ensembl chr 9:21,015,985...21,028,817
JBrowse link
G Ifng interferon gamma multiple interactions ISO
EXP
deguelin inhibits the reaction [Perfadex results in increased expression of IFNG protein]
[deguelin co-treated with OVAL protein] results in increased expression of IFNG protein
CTD PMID:22745725 PMID:28529457 NCBI chr10:118,441,046...118,445,894
Ensembl chr10:118,441,046...118,445,892
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO deguelin inhibits the reaction [IGF1 protein results in increased expression of HIF1A protein]; deguelin inhibits the reaction [IGF1 protein results in increased expression of VEGFA mRNA] CTD PMID:17764071 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Igf1r insulin-like growth factor I receptor decreases expression ISO deguelin metabolite results in decreased expression of IGF1R protein; deguelin results in decreased expression of IGF1R protein CTD PMID:19139008 NCBI chr 7:67,952,257...68,233,668
Ensembl chr 7:67,952,827...68,233,668
JBrowse link
G Ihh Indian hedgehog increases expression ISO deguelin results in increased expression of IHH mRNA CTD PMID:19861542 NCBI chr 1:74,945,315...74,951,672
Ensembl chr 1:74,945,315...74,951,672
JBrowse link
G Il10 interleukin 10 multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of IL10 mRNA] CTD PMID:22745725 NCBI chr 1:131,019,845...131,024,970
Ensembl chr 1:131,019,845...131,024,974
JBrowse link
G Il13 interleukin 13 multiple interactions EXP deguelin inhibits the reaction [OVAL protein results in increased expression of IL13 protein] CTD PMID:28529457 NCBI chr11:53,631,323...53,634,702
Ensembl chr11:53,631,324...53,634,702
JBrowse link
G Il4 interleukin 4 multiple interactions ISO
EXP
deguelin inhibits the reaction [Oxygen deficiency results in decreased expression of IL4 mRNA]
deguelin inhibits the reaction [OVAL protein results in increased expression of IL4 mRNA]; deguelin inhibits the reaction [OVAL protein results in increased expression of IL4 protein]
CTD PMID:22745725 PMID:28529457 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il5 interleukin 5 multiple interactions EXP deguelin inhibits the reaction [OVAL protein results in increased expression of IL5 protein] CTD PMID:28529457 NCBI chr11:53,720,794...53,725,103
Ensembl chr11:53,720,794...53,725,106
JBrowse link
G Il6 interleukin 6 multiple interactions ISO deguelin inhibits the reaction [Perfadex results in decreased expression of IL6 protein] CTD PMID:22745725 NCBI chr 5:30,013,114...30,019,975
Ensembl chr 5:30,013,114...30,019,981
JBrowse link
G Itgam integrin alpha M multiple interactions ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of ITGAM protein CTD PMID:25242579 NCBI chr 7:128,062,640...128,118,491
Ensembl chr 7:128,062,640...128,118,491
JBrowse link
G Jun jun proto-oncogene increases phosphorylation ISO deguelin results in increased phosphorylation of JUN protein CTD PMID:25322282 NCBI chr 4:95,049,036...95,052,222
Ensembl chr 4:95,049,034...95,052,222
JBrowse link
G Kdr kinase insert domain protein receptor decreases expression ISO deguelin metabolite results in decreased expression of KDR protein; deguelin results in decreased expression of KDR protein CTD PMID:19139008 NCBI chr 5:75,932,827...75,979,072
Ensembl chr 5:75,932,827...75,978,458
JBrowse link
G Krt18 keratin 18 multiple interactions
increases expression
ISO deguelin inhibits the reaction [TGFB1 protein results in decreased expression of KRT18 protein]
deguelin results in increased expression of KRT18 protein
CTD PMID:22986522 NCBI chr15:102,028,216...102,032,026
Ensembl chr15:102,028,180...102,032,027
JBrowse link
G Lox lysyl oxidase multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of LOX mRNA] CTD PMID:22745725 NCBI chr18:52,516,060...52,529,867
Ensembl chr18:52,516,067...52,529,867
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 decreases expression ISO deguelin metabolite results in decreased expression of MAP2K1 protein; deguelin results in decreased expression of MAP2K1 protein CTD PMID:19139008 PMID:19336726 NCBI chr 9:64,185,769...64,253,605
Ensembl chr 9:64,185,770...64,253,631
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 decreases expression ISO deguelin results in decreased expression of MAP2K2 protein CTD PMID:19336726 NCBI chr10:81,105,913...81,124,697
Ensembl chr10:81,105,915...81,133,975
JBrowse link
G Map2k7 mitogen-activated protein kinase kinase 7 decreases expression ISO deguelin results in decreased expression of MAP2K7 protein CTD PMID:25322282 NCBI chr 8:4,238,740...4,247,897
Ensembl chr 8:4,238,740...4,247,897
Ensembl chr 8:4,238,740...4,247,897
JBrowse link
G Map3k3 mitogen-activated protein kinase kinase kinase 3 affects expression ISO deguelin affects the expression of MAP3K3 protein CTD PMID:25322282 NCBI chr11:106,084,587...106,156,656
Ensembl chr11:106,084,613...106,155,446
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 affects phosphorylation ISO deguelin affects the phosphorylation of MAPK1 protein CTD PMID:25322282 NCBI chr16:16,983,382...17,047,453
Ensembl chr16:16,983,382...17,047,453
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 affects phosphorylation ISO deguelin affects the phosphorylation of MAPK3 protein CTD PMID:25322282 NCBI chr 7:126,759,626...126,765,816
Ensembl chr 7:126,759,601...126,765,819
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 decreases expression ISO deguelin results in decreased expression of MCL1 protein CTD PMID:21472727 NCBI chr 3:95,656,944...95,663,179
Ensembl chr 3:95,658,788...95,663,176
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases expression ISO deguelin results in decreased expression of MGMT mRNA CTD PMID:22227970 NCBI chr 7:136,894,463...137,128,193
Ensembl chr 7:136,894,614...137,130,266
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 decreases expression ISO deguelin results in decreased expression of MKI67 protein CTD PMID:22623043 NCBI chr 7:135,689,784...135,716,450
Ensembl chr 7:135,689,784...135,716,361
JBrowse link
G Mmp13 matrix metallopeptidase 13 decreases expression ISO deguelin results in decreased expression of MMP13 protein CTD PMID:25322282 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) decreases expression ISO deguelin results in decreased expression of MMP1 protein CTD PMID:25322282 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO deguelin results in decreased expression of and results in decreased activity of MMP2 protein
deguelin results in decreased expression of MMP2 mRNA; deguelin results in decreased expression of MMP2 protein
CTD PMID:25322282 PMID:26884827 NCBI chr 8:92,827,290...92,853,421
Ensembl chr 8:92,827,291...92,853,420
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO deguelin results in decreased expression of MMP7 mRNA CTD PMID:25322282 NCBI chr 9:7,692,090...7,699,585
Ensembl chr 9:7,692,090...7,699,585
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
decreases activity
ISO deguelin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]
deguelin results in decreased expression of MMP9 mRNA; deguelin results in decreased expression of MMP9 protein
deguelin results in decreased activity of MMP9 protein
CTD PMID:17015749 PMID:25322282 PMID:26884827 NCBI chr 2:164,940,326...164,955,850
Ensembl chr 2:164,940,780...164,955,850
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions ISO deguelin promotes the reaction [Oxygen deficiency results in increased expression of MRC1 mRNA] CTD PMID:22745725 NCBI chr 2:14,229,414...14,332,023
Ensembl chr 2:14,229,392...14,332,057
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of MTOR protein; deguelin results in decreased expression of MTOR protein
deguelin results in decreased phosphorylation of MTOR protein
CTD PMID:19139008 PMID:27255535 NCBI chr 4:148,448,582...148,557,685
Ensembl chr 4:148,448,611...148,557,683
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric multiple interactions EXP deguelin inhibits the reaction [OVAL protein results in increased expression of MUC5AC mRNA] CTD PMID:28529457 NCBI chr 7:141,788,958...141,819,227
Ensembl chr 7:141,788,972...141,819,231
JBrowse link
G Myc myelocytomatosis oncogene multiple interactions
decreases expression
ISO
EXP
[deguelin results in increased degradation of CTNNB1 protein] which results in decreased expression of MYC protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [deguelin results in decreased expression of MYC protein]; deguelin inhibits the reaction [TNF protein results in increased expression of MYC protein]
deguelin inhibits the reaction [MYC protein results in increased activity of ODC1 protein]
CTD PMID:9270009 PMID:17015749 PMID:21472727 NCBI chr15:61,985,341...61,990,361
Ensembl chr15:61,985,391...61,990,374
JBrowse link
G Ncoa3 nuclear receptor coactivator 3 decreases expression ISO deguelin results in decreased expression of NCOA3 mRNA; deguelin results in decreased expression of NCOA3 protein CTD PMID:19365708 NCBI chr 2:165,992,637...166,073,242
Ensembl chr 2:165,992,636...166,073,242
JBrowse link
G Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 decreases expression ISO deguelin results in decreased expression of NEK2 mRNA; deguelin results in decreased expression of NEK2 protein CTD PMID:28509438 NCBI chr 1:191,821,449...191,833,049
Ensembl chr 1:191,821,444...191,833,050
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions ISO
EXP
deguelin inhibits the reaction [TNF protein results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
deguelin inhibits the reaction [OVAL protein results in increased degradation of and results in increased phosphorylation of NFKBIA protein]
CTD PMID:17015749 PMID:22623043 PMID:28529457 NCBI chr12:55,489,409...55,492,647
Ensembl chr12:55,489,410...55,492,647
JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression
multiple interactions
ISO
EXP
deguelin results in decreased expression of NOS2 protein
deguelin inhibits the reaction [OVAL protein results in increased expression of NOS2 mRNA]
CTD PMID:25322282 PMID:28529457 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell decreases expression ISO deguelin results in decreased expression of NOS3 protein CTD PMID:19336726 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Npm1 nucleophosmin 1 decreases expression
multiple interactions
increases response to substance
ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CDKN1A protein; [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of CEBPA protein; [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of TP53 protein
[NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP6 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in decreased expression of and results in increased activity of CASP8 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of CASP3 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of PARP1 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of CD14 protein; [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased expression of ITGAM protein
CTD PMID:25242579 NCBI chr11:33,152,498...33,164,142
Ensembl chr11:33,152,287...33,163,206
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO deguelin inhibits the reaction [Oxygen deficiency results in increased expression of NT5E protein] CTD PMID:27899277 NCBI chr 9:88,327,609...88,372,089
Ensembl chr 9:88,327,197...88,372,092
JBrowse link
G Nup98 nucleoporin 98 decreases expression ISO deguelin results in decreased expression of NUP98 mRNA; deguelin results in decreased expression of NUP98 protein CTD PMID:17490514 NCBI chr 7:102,119,400...102,210,166
Ensembl chr 7:102,119,398...102,210,176
JBrowse link
G Odc1 ornithine decarboxylase, structural 1 increases activity
multiple interactions
ISO
EXP
deguelin results in increased activity of ODC1 protein
deguelin inhibits the reaction [MYC protein results in increased activity of ODC1 protein]; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]
CTD PMID:9270009 PMID:9834970 NCBI chr12:17,544,808...17,551,502
Ensembl chr12:17,544,794...17,551,505
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases cleavage
increases expression
ISO [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of PARP1 protein; deguelin inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein]
deguelin results in increased cleavage of PARP1 protein
deguelin metabolite results in increased expression of PARP1 protein modified form; deguelin results in increased expression of PARP1 protein modified form
CTD PMID:17015749 PMID:17035597 PMID:19139008 PMID:22986522 PMID:25242579 NCBI chr 1:180,568,891...180,600,999
Ensembl chr 1:180,568,924...180,601,254
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 decreases expression ISO deguelin metabolite results in decreased expression of PDK1 protein; deguelin results in decreased expression of PDK1 protein CTD PMID:19139008 NCBI chr 2:71,873,215...71,903,858
Ensembl chr 2:71,873,224...71,903,858
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha decreases expression ISO deguelin metabolite results in decreased expression of PIK3CA protein; deguelin results in decreased expression of PIK3CA protein CTD PMID:19139008 NCBI chr 3:32,397,065...32,466,112
Ensembl chr 3:32,397,671...32,468,486
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation EXP deguelin results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 2:160,731,310...160,775,760
Ensembl chr 2:160,731,300...160,775,760
JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory inhibitor subunit 1B multiple interactions EXP deguelin inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein] CTD PMID:17209049 NCBI chr11:98,348,406...98,357,796
Ensembl chr11:98,348,404...98,357,796
JBrowse link
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit increases phosphorylation EXP deguelin results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr15:5,143,861...5,181,899
Ensembl chr15:5,143,861...5,181,899
JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide decreases expression ISO deguelin results in decreased expression of PRKDC mRNA CTD PMID:22227970 NCBI chr16:15,637,444...15,842,239
Ensembl chr16:15,637,866...15,842,235
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
ISO deguelin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
deguelin results in decreased expression of PTGS2 protein
CTD PMID:17015749 PMID:25322282 NCBI chr 1:150,100,031...150,108,234
Ensembl chr 1:150,100,031...150,108,227
JBrowse link
G Ptk2 PTK2 protein tyrosine kinase 2 decreases expression ISO deguelin results in decreased expression of PTK2 protein CTD PMID:25322282 NCBI chr15:73,205,102...73,423,820
Ensembl chr15:73,205,102...73,423,280
JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression ISO deguelin results in decreased expression of RAC1 protein CTD PMID:26884827 NCBI chr 5:143,505,481...143,528,031
Ensembl chr 5:143,503,634...143,528,036
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO deguelin results in decreased expression of RB1 protein CTD PMID:15960896 NCBI chr14:73,192,858...73,325,951
Ensembl chr14:73,183,673...73,325,822
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) decreases expression
multiple interactions
decreases phosphorylation
ISO
EXP
deguelin results in decreased expression of RELA mRNA; deguelin results in decreased expression of RELA protein
deguelin inhibits the reaction [OVAL protein affects the localization of and results in increased phosphorylation of RELA protein]
deguelin results in decreased phosphorylation of RELA protein
deguelin inhibits the reaction [TNF protein affects the localization of and results in increased phosphorylation of RELA protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and affects the localization of RELA protein]
CTD PMID:17015749 PMID:19365708 PMID:22623043 PMID:28529457 NCBI chr19:5,637,442...5,648,134
Ensembl chr19:5,637,483...5,648,130
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO deguelin results in decreased expression of RHOA mRNA; deguelin results in decreased expression of RHOA protein CTD PMID:25322282 NCBI chr 9:108,306,160...108,337,943
Ensembl chr 9:108,306,129...108,337,934
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression ISO deguelin results in decreased expression of ROCK1 protein CTD PMID:25322282 PMID:26884827 NCBI chr18:10,064,401...10,182,251
Ensembl chr18:10,064,401...10,182,045
JBrowse link
G Rps6 ribosomal protein S6 decreases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of RPS6 protein; deguelin metabolite results in decreased expression of RPS6 protein modified form; deguelin results in decreased expression of RPS6 protein; deguelin results in decreased expression of RPS6 protein modified form
deguelin results in decreased phosphorylation of RPS6 protein
CTD PMID:19139008 PMID:27255535 NCBI chr 4:86,854,099...86,857,367
Ensembl chr 4:86,854,660...86,857,412
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 decreases expression
decreases phosphorylation
ISO deguelin metabolite results in decreased expression of RPS6KB1 protein; deguelin results in decreased expression of RPS6KB1 protein
deguelin results in decreased phosphorylation of RPS6KB1 protein
CTD PMID:19139008 PMID:27255535 NCBI chr11:86,498,869...86,544,885
Ensembl chr11:86,498,871...86,544,805
JBrowse link
G Sele selectin, endothelial cell multiple interactions ISO
EXP
deguelin inhibits the reaction [TNF protein results in increased expression of SELE mRNA]
deguelin inhibits the reaction [OVAL protein results in increased expression of SELE mRNA]
CTD PMID:28529457 NCBI chr 1:164,039,614...164,058,487
Ensembl chr 1:164,048,234...164,057,677
JBrowse link
G Serpinb3d serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D decreases secretion ISO deguelin results in decreased secretion of SERPINB3 protein CTD PMID:26884827 NCBI chr 1:107,078,163...107,083,480
Ensembl chr 1:107,078,167...107,083,506
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression ISO deguelin results in decreased expression of SFRP2 mRNA CTD PMID:19861542 NCBI chr 3:83,765,750...83,774,314
Ensembl chr 3:83,766,321...83,774,316
JBrowse link
G Smad3 SMAD family member 3 decreases phosphorylation ISO deguelin results in decreased phosphorylation of SMAD3 protein CTD PMID:22986522 NCBI chr 9:63,646,766...63,757,994
Ensembl chr 9:63,646,767...63,757,994
JBrowse link
G Smad4 SMAD family member 4 multiple interactions ISO deguelin inhibits the reaction [TGFB1 protein affects the localization of SMAD4 protein] CTD PMID:22986522 NCBI chr18:73,634,790...73,703,791
Ensembl chr18:73,639,009...73,703,780
JBrowse link
G Snai1 snail family zinc finger 1 decreases expression
multiple interactions
ISO deguelin results in decreased expression of SNAI1 mRNA; deguelin results in decreased expression of SNAI1 protein
deguelin inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein]
CTD PMID:19861542 PMID:22986522 NCBI chr 2:167,538,195...167,542,814
Ensembl chr 2:167,538,195...167,542,814
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 decreases expression ISO deguelin results in decreased expression of SOS1 protein CTD PMID:25322282 NCBI chr17:80,393,752...80,480,453
Ensembl chr17:80,393,751...80,480,453
JBrowse link
G Sox14 SRY (sex determining region Y)-box 14 increases expression ISO deguelin results in increased expression of SOX14 mRNA CTD PMID:19861542 NCBI chr 9:99,874,106...99,876,170
Ensembl chr 9:99,874,106...99,876,170
JBrowse link
G Sox30 SRY (sex determining region Y)-box 30 increases expression ISO deguelin results in increased expression of SOX30 mRNA CTD PMID:19861542 NCBI chr11:45,979,069...46,017,992
Ensembl chr11:45,980,310...46,017,994
JBrowse link
G Sox5 SRY (sex determining region Y)-box 5 increases expression ISO deguelin results in increased expression of SOX5 mRNA CTD PMID:19861542 NCBI chr 6:143,828,425...144,782,287
Ensembl chr 6:143,828,425...144,781,977
JBrowse link
G Src Rous sarcoma oncogene increases activity ISO deguelin metabolite results in increased activity of SRC protein; deguelin results in increased activity of SRC protein CTD PMID:19139008 NCBI chr 2:157,423,906...157,471,838
Ensembl chr 2:157,418,444...157,471,862
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases activity ISO deguelin metabolite results in increased activity of STAT3 protein; deguelin results in increased activity of STAT3 protein CTD PMID:19139008 NCBI chr11:100,886,806...100,939,594
Ensembl chr11:100,885,098...100,939,540
JBrowse link
G Stat6 signal transducer and activator of transcription 6 increases phosphorylation ISO deguelin metabolite results in increased phosphorylation of STAT6 protein; deguelin results in increased phosphorylation of STAT6 protein CTD PMID:19139008 NCBI chr10:127,642,955...127,660,987
Ensembl chr10:127,642,986...127,660,957
JBrowse link
G Sts steroid sulfatase multiple interactions ISO deguelin inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010
G Tcf4 transcription factor 4 increases expression ISO deguelin results in increased expression of TCF4 mRNA CTD PMID:19861542 NCBI chr18:69,343,429...69,687,967
Ensembl chr18:69,343,356...69,689,079
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO deguelin inhibits the reaction [TGFB1 protein affects the localization of SMAD4 protein]; deguelin inhibits the reaction [TGFB1 protein results in decreased expression of KRT18 protein]; deguelin inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; deguelin inhibits the reaction [TGFB1 protein results in increased expression of SNAI1 protein] CTD PMID:22986522 NCBI chr 7:25,687,002...25,705,077
Ensembl chr 7:25,687,002...25,705,077
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression ISO deguelin results in increased expression of TIMP1 protein CTD PMID:25322282 NCBI chr  X:20,870,166...20,874,737
Ensembl chr  X:20,870,166...20,874,735
JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 increases expression ISO deguelin results in increased expression of TIMP2 protein CTD PMID:25322282 NCBI chr11:118,301,061...118,355,411
Ensembl chr11:118,301,069...118,355,740
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO deguelin inhibits the reaction [TNF protein affects the localization of and results in increased phosphorylation of RELA protein]; deguelin inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein]; deguelin inhibits the reaction [TNF protein results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; deguelin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of MUC mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of MYC protein]; deguelin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of TSLP mRNA]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and affects the localization of RELA protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein] CTD PMID:17015749 PMID:22623043 PMID:28529457 NCBI chr17:35,199,367...35,202,007
Ensembl chr17:35,199,381...35,202,007
JBrowse link
G Trp53 transformation related protein 53 decreases expression ISO [deguelin results in decreased expression of NPM1 protein mutant form] which results in decreased expression of TP53 protein; deguelin results in decreased expression of TP53 mRNA CTD PMID:22227970 PMID:25242579 NCBI chr11:69,580,348...69,591,873
Ensembl chr11:69,580,359...69,591,873
JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions EXP
ISO
deguelin inhibits the reaction [OVAL protein results in increased expression of TSLP mRNA]; deguelin inhibits the reaction [OVAL protein results in increased expression of TSLP protein]
deguelin inhibits the reaction [TNF protein results in increased expression of TSLP mRNA]
CTD PMID:28529457 NCBI chr18:32,815,383...32,819,799
Ensembl chr18:32,815,383...32,819,797
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
decreases expression
decreases response to substance
ISO deguelin inhibits the reaction [IGF1 protein results in increased expression of VEGFA mRNA]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]; deguelin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein]
deguelin results in decreased expression of VEGFA protein
VEGFA protein results in decreased susceptibility to deguelin
CTD PMID:17764071 PMID:18575727 PMID:22623043 PMID:22745725 PMID:25322282 NCBI chr17:46,016,993...46,032,377
Ensembl chr17:46,016,993...46,032,369
JBrowse link
G Vim vimentin decreases expression ISO deguelin results in decreased expression of VIM protein CTD PMID:22986522 PMID:28509438 NCBI chr 2:13,574,311...13,582,826
Ensembl chr 2:13,573,927...13,582,826
JBrowse link
G Wif1 Wnt inhibitory factor 1 increases expression ISO deguelin results in increased expression of WIF1 mRNA CTD PMID:19861542 NCBI chr10:121,034,004...121,100,642
Ensembl chr10:121,033,960...121,100,650
JBrowse link
G Wnt10a wingless-type MMTV integration site family, member 10A increases expression ISO deguelin results in increased expression of WNT10A mRNA CTD PMID:19861542 NCBI chr 1:74,792,019...74,804,176
Ensembl chr 1:74,791,516...74,804,179
JBrowse link
G Wnt11 wingless-type MMTV integration site family, member 11 increases expression ISO deguelin results in increased expression of WNT11 mRNA CTD PMID:19861542 NCBI chr 7:98,835,084...98,854,747
Ensembl chr 7:98,835,112...98,855,195
JBrowse link
G Wnt2 wingless-type MMTV integration site family, member 2 increases expression ISO deguelin results in increased expression of WNT2 mRNA CTD PMID:19861542 NCBI chr 6:17,985,474...18,032,772
Ensembl chr 6:17,988,940...18,030,585
JBrowse link
G Wnt2b wingless-type MMTV integration site family, member 2B decreases expression ISO deguelin results in decreased expression of WNT2B mRNA CTD PMID:19861542 NCBI chr 3:104,944,805...104,961,709
Ensembl chr 3:104,945,272...104,961,921
JBrowse link
G Wnt3a wingless-type MMTV integration site family, member 3A decreases expression ISO deguelin results in decreased expression of WNT3A mRNA CTD PMID:19861542 NCBI chr11:59,248,036...59,290,751
Ensembl chr11:59,248,033...59,290,752
JBrowse link
G Wnt9a wingless-type MMTV integration site family, member 9A decreases expression ISO deguelin results in decreased expression of WNT9A mRNA CTD PMID:19861542 NCBI chr11:59,306,849...59,333,552
Ensembl chr11:59,306,928...59,333,552
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO deguelin results in decreased expression of XIAP protein CTD PMID:17035597 NCBI chr  X:42,059,613...42,109,664
Ensembl chr  X:42,059,679...42,109,656
JBrowse link
Osajin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase increases expression ISO osajin results in increased expression of ACLY mRNA CTD PMID:20706672 NCBI chr11:100,476,352...100,528,000
Ensembl chr11:100,476,353...100,528,000
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO osajin results in increased expression of AQP1 mRNA CTD PMID:20706672 NCBI chr 6:55,336,299...55,348,555
Ensembl chr 6:55,336,432...55,348,555
JBrowse link
G Aqp3 aquaporin 3 increases expression ISO osajin results in increased expression of AQP3 mRNA CTD PMID:20706672 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Ar androgen receptor decreases expression ISO osajin results in decreased expression of AR mRNA CTD PMID:20706672 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Cd44 CD44 antigen increases expression ISO osajin results in increased expression of CD44 mRNA CTD PMID:20706672 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665
JBrowse link
G Cdh1 cadherin 1 increases expression ISO osajin results in increased expression of CDH1 mRNA CTD PMID:20706672 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246
JBrowse link
G Col1a1 collagen, type I, alpha 1 increases expression ISO osajin results in increased expression of COL1A1 mRNA CTD PMID:20706672 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Cygb cytoglobin decreases expression ISO osajin results in decreased expression of CYGB mRNA CTD PMID:20706672 NCBI chr11:116,645,595...116,654,504
Ensembl chr11:116,645,595...116,654,313
JBrowse link
G Dsg3 desmoglein 3 decreases expression ISO osajin results in decreased expression of DSG3 mRNA CTD PMID:20706672 NCBI chr18:20,510,274...20,541,310
Ensembl chr18:20,510,274...20,547,459
JBrowse link
G Egf epidermal growth factor decreases expression ISO osajin results in decreased expression of EGF mRNA CTD PMID:20706672 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316
JBrowse link
G Esr2 estrogen receptor 2 (beta) decreases expression ISO osajin results in decreased expression of ESR2 mRNA CTD PMID:20706672 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO osajin results in increased expression of FGF1 mRNA CTD PMID:20706672 NCBI chr18:38,838,672...38,929,470
Ensembl chr18:38,838,673...38,929,472
JBrowse link
G Grn granulin increases expression ISO osajin results in increased expression of GRN mRNA CTD PMID:20706672 NCBI chr11:102,430,507...102,436,809
Ensembl chr11:102,430,315...102,437,048
JBrowse link
G Has1 hyaluronan synthase 1 decreases expression ISO osajin results in decreased expression of HAS1 mRNA CTD PMID:20706672 NCBI chr17:17,833,691...17,855,589
Ensembl chr17:17,843,323...17,855,205
JBrowse link
G Hspb1 heat shock protein 1 increases expression ISO osajin results in increased expression of HSPB1 mRNA CTD PMID:20706672 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO osajin results in decreased expression of IGF1 mRNA CTD PMID:20706672 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Il1a interleukin 1 alpha decreases expression ISO osajin results in decreased expression of IL1A mRNA CTD PMID:20706672 NCBI chr 2:129,299,609...129,310,186
Ensembl chr 2:129,299,610...129,309,972
JBrowse link
G Kl klotho decreases expression ISO osajin results in decreased expression of KL mRNA CTD PMID:20706672 NCBI chr 5:150,952,607...150,993,817
Ensembl chr 5:150,952,607...150,993,817
JBrowse link
G Krt5 keratin 5 increases expression ISO osajin results in increased expression of KRT5 mRNA CTD PMID:20706672 NCBI chr15:101,707,069...101,712,905
Ensembl chr15:101,707,070...101,712,898
JBrowse link
G Mc1r melanocortin 1 receptor decreases expression ISO osajin results in decreased expression of MC1R mRNA CTD PMID:20706672 NCBI chr 8:123,407,082...123,410,744
Ensembl chr 8:123,407,107...123,410,744
JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial increases expression ISO osajin results in increased expression of COX1 mRNA CTD PMID:20706672 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
JBrowse link
G Nos2 nitric oxide synthase 2, inducible decreases expression ISO osajin results in decreased expression of NOS2 mRNA CTD PMID:20706672 NCBI chr11:78,920,787...78,960,226
Ensembl chr11:78,920,787...78,960,254
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell increases expression ISO osajin results in increased expression of NOS3 mRNA CTD PMID:20706672 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Pgr progesterone receptor decreases expression ISO osajin results in decreased expression of PGR mRNA CTD PMID:20706672 NCBI chr 9:8,898,900...8,968,611
Ensembl chr 9:8,899,833...8,968,611
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 increases expression ISO osajin results in increased expression of PLOD3 mRNA CTD PMID:20706672 NCBI chr 5:136,987,019...136,996,646
Ensembl chr 5:136,987,019...136,996,648
JBrowse link
G Pomc pro-opiomelanocortin-alpha decreases expression ISO osajin results in decreased expression of POMC mRNA CTD PMID:20706672 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression ISO osajin results in decreased expression of PPARG mRNA CTD PMID:20706672 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ptger1 prostaglandin E receptor 1 (subtype EP1) decreases expression ISO osajin results in decreased expression of PTGER1 mRNA CTD PMID:20706672 NCBI chr 8:83,666,644...83,672,756
Ensembl chr 8:83,666,678...83,672,753
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO osajin results in decreased expression of RAD23A mRNA CTD PMID:20706672 NCBI chr 8:84,834,927...84,840,652
Ensembl chr 8:84,834,019...84,840,665
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO osajin results in increased expression of RARA mRNA CTD PMID:20706672 NCBI chr11:98,927,800...98,974,942
Ensembl chr11:98,927,818...98,974,942
JBrowse link
G Rxra retinoid X receptor alpha decreases expression ISO osajin results in decreased expression of RXRA mRNA CTD PMID:20706672 NCBI chr 2:27,676,445...27,763,319
Ensembl chr 2:27,676,440...27,762,957
JBrowse link
G Sod3 superoxide dismutase 3, extracellular decreases expression ISO osajin results in decreased expression of SOD3 mRNA CTD PMID:20706672 NCBI chr 5:52,363,804...52,369,738
Ensembl chr 5:52,363,791...52,371,418
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO osajin results in decreased expression of SRD5A2 mRNA CTD PMID:20706672 NCBI chr17:74,014,891...74,047,860
Ensembl chr17:74,016,955...74,047,916
JBrowse link
G Tert telomerase reverse transcriptase decreases expression ISO osajin results in decreased expression of TERT mRNA CTD PMID:20706672 NCBI chr13:73,626,911...73,649,843
Ensembl chr13:73,626,911...73,649,843
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression ISO osajin results in increased expression of TPT1 mRNA CTD PMID:20706672 NCBI chr14:75,845,256...75,848,303
Ensembl chr14:75,845,093...75,848,525
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO osajin results in increased expression of TXN mRNA CTD PMID:20706672 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
Pomiferin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase increases expression ISO pomiferin results in increased expression of ACLY mRNA CTD PMID:20706672 NCBI chr11:100,476,352...100,528,000
Ensembl chr11:100,476,353...100,528,000
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO pomiferin results in increased expression of AQP1 mRNA CTD PMID:20706672 NCBI chr 6:55,336,299...55,348,555
Ensembl chr 6:55,336,432...55,348,555
JBrowse link
G Aqp3 aquaporin 3 increases expression ISO pomiferin results in increased expression of AQP3 mRNA CTD PMID:20706672 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Ar androgen receptor decreases expression ISO pomiferin results in decreased expression of AR mRNA CTD PMID:20706672 NCBI chr  X:98,148,757...98,323,218
Ensembl chr  X:98,148,769...98,323,215
JBrowse link
G Cd44 CD44 antigen increases expression ISO pomiferin results in increased expression of CD44 mRNA CTD PMID:20706672 NCBI chr 2:102,811,141...102,901,669
Ensembl chr 2:102,811,141...102,901,665
JBrowse link
G Cdh1 cadherin 1 increases expression ISO pomiferin results in increased expression of CDH1 mRNA CTD PMID:20706672 NCBI chr 8:106,603,350...106,670,247
Ensembl chr 8:106,603,351...106,670,246
JBrowse link
G Col1a1 collagen, type I, alpha 1 increases expression ISO pomiferin results in increased expression of COL1A1 mRNA CTD PMID:20706672 NCBI chr11:94,936,224...94,953,042
Ensembl chr11:94,936,224...94,953,042
JBrowse link
G Cygb cytoglobin decreases expression ISO pomiferin results in decreased expression of CYGB mRNA CTD PMID:20706672 NCBI chr11:116,645,595...116,654,504
Ensembl chr11:116,645,595...116,654,313
JBrowse link
G Egf epidermal growth factor decreases expression ISO pomiferin results in decreased expression of EGF mRNA CTD PMID:20706672 NCBI chr 3:129,677,574...129,755,322
Ensembl chr 3:129,677,565...129,755,316
JBrowse link
G Esr2 estrogen receptor 2 (beta) decreases expression ISO pomiferin results in decreased expression of ESR2 mRNA CTD PMID:20706672 NCBI chr12:76,120,419...76,177,259
Ensembl chr12:76,120,419...76,177,259
JBrowse link
G Fbn1 fibrillin 1 decreases expression ISO pomiferin results in decreased expression of FBN1 mRNA CTD PMID:20706672 NCBI chr 2:125,300,594...125,506,485
Ensembl chr 2:125,300,594...125,507,993
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO pomiferin results in increased expression of FGF1 mRNA CTD PMID:20706672 NCBI chr18:38,838,672...38,929,470
Ensembl chr18:38,838,673...38,929,472
JBrowse link
G Grn granulin increases expression ISO pomiferin results in increased expression of GRN mRNA CTD PMID:20706672 NCBI chr11:102,430,507...102,436,809
Ensembl chr11:102,430,315...102,437,048
JBrowse link
G Hspb1 heat shock protein 1 increases expression ISO pomiferin results in increased expression of HSPB1 mRNA CTD PMID:20706672 NCBI chr 5:135,887,919...135,889,563
Ensembl chr 5:135,887,919...135,889,563
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO pomiferin results in decreased expression of IGF1 mRNA CTD PMID:20706672 NCBI chr10:87,858,265...87,937,047
Ensembl chr10:87,858,265...87,937,042
JBrowse link
G Kl klotho decreases expression ISO pomiferin results in decreased expression of KL mRNA CTD PMID:20706672 NCBI chr 5:150,952,607...150,993,817
Ensembl chr 5:150,952,607...150,993,817
JBrowse link
G Krt5 keratin 5 increases expression ISO pomiferin results in increased expression of KRT5 mRNA CTD PMID:20706672 NCBI chr15:101,707,069...101,712,905
Ensembl chr15:101,707,070...101,712,898
JBrowse link
G Mc1r melanocortin 1 receptor decreases expression ISO pomiferin results in decreased expression of MC1R mRNA CTD PMID:20706672 NCBI chr 8:123,407,082...123,410,744
Ensembl chr 8:123,407,107...123,410,744
JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial increases expression ISO pomiferin results in increased expression of COX1 mRNA CTD PMID:20706672 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell increases expression ISO pomiferin results in increased expression of NOS3 mRNA CTD PMID:20706672 NCBI chr 5:24,364,816...24,384,474
Ensembl chr 5:24,364,810...24,384,474
JBrowse link
G Pgr progesterone receptor decreases expression ISO pomiferin results in decreased expression of PGR mRNA CTD PMID:20706672 NCBI chr 9:8,898,900...8,968,611
Ensembl chr 9:8,899,833...8,968,611
JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 increases expression ISO pomiferin results in increased expression of PLOD3 mRNA CTD PMID:20706672 NCBI chr 5:136,987,019...136,996,646
Ensembl chr 5:136,987,019...136,996,648
JBrowse link
G Pomc pro-opiomelanocortin-alpha decreases expression ISO pomiferin results in decreased expression of POMC mRNA CTD PMID:20706672 NCBI chr12:3,954,945...3,960,643
Ensembl chr12:3,954,951...3,960,642
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression ISO pomiferin results in decreased expression of PPARG mRNA CTD PMID:20706672 NCBI chr 6:115,360,879...115,490,404
Ensembl chr 6:115,360,951...115,490,399
JBrowse link
G Ptger1 prostaglandin E receptor 1 (subtype EP1) decreases expression ISO pomiferin results in decreased expression of PTGER1 mRNA CTD PMID:20706672 NCBI chr 8:83,666,644...83,672,756
Ensembl chr 8:83,666,678...83,672,753
JBrowse link
G Rad23a RAD23 homolog A, nucleotide excision repair protein decreases expression ISO pomiferin results in decreased expression of RAD23A mRNA CTD PMID:20706672 NCBI chr 8:84,834,927...84,840,652
Ensembl chr 8:84,834,019...84,840,665
JBrowse link
G Rara retinoic acid receptor, alpha increases expression ISO pomiferin results in increased expression of RARA mRNA CTD PMID:20706672 NCBI chr11:98,927,800...98,974,942
Ensembl chr11:98,927,818...98,974,942
JBrowse link
G Sod3 superoxide dismutase 3, extracellular decreases expression ISO pomiferin results in decreased expression of SOD3 mRNA CTD PMID:20706672 NCBI chr 5:52,363,804...52,369,738
Ensembl chr 5:52,363,791...52,371,418
JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 decreases expression ISO pomiferin results in decreased expression of SRD5A2 mRNA CTD PMID:20706672 NCBI chr17:74,014,891...74,047,860
Ensembl chr17:74,016,955...74,047,916
JBrowse link
G Tert telomerase reverse transcriptase decreases expression ISO pomiferin results in decreased expression of TERT mRNA CTD PMID:20706672 NCBI chr13:73,626,911...73,649,843
Ensembl chr13:73,626,911...73,649,843
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression ISO pomiferin results in increased expression of TPT1 mRNA CTD PMID:20706672 NCBI chr14:75,845,256...75,848,303
Ensembl chr14:75,845,093...75,848,525
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO pomiferin results in increased expression of TXN mRNA CTD PMID:20706672 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO pomiferin results in decreased expression of TYRP1 mRNA CTD PMID:20706672 NCBI chr 4:80,834,123...80,851,736
Ensembl chr 4:80,834,123...80,851,719
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21560
    chemical entity 21558
      group 21417
        inorganic group 20214
          oxo group 19540
            organic oxo compound 19540
              carbonyl compound 19540
                ketone 16727
                  cyclic ketone 14289
                    isoflavanones 185
                      (+)-Sophorol 0
                      (+-)-5-Deoxykievitone 0
                      (-)-Sophorol 0
                      3-(1,3-benzodioxol-5-yl)-5,7-dihydroxy-6-(3-methylbut-2-enyl)-1-benzopyran-4-one 0
                      7-(1,3-benzodioxol-5-yl)-5-methoxy-2,2-dimethyl-6-pyrano[3,2-g][1]benzopyranone 0
                      Cyclokievitone 0
                      Deguelin 147
                      Euchretin A 0
                      Lachnoisoflavones A, (rac)- 0
                      Lachnoisoflavones B 0
                      Licoagroisoflavone 0
                      Millettone 0
                      Osajin 36
                      Pomiferin 33
                      Sumatrol 0
                      Toxicarol 0
                      alpinumisoflavone 14
                      hydroxyisoflavanone + 5
                      isoflavanone + 5
                      methoxyisoflavanone + 5
                      sophoraisoflavanone B 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21560
    subatomic particle 21546
      composite particle 21546
        hadron 21546
          baryon 21546
            nucleon 21546
              atomic nucleus 21546
                atom 21546
                  main group element atom 21449
                    p-block element atom 21449
                      carbon group element atom 21240
                        carbon atom 21135
                          organic molecular entity 21135
                            organic molecule 21027
                              organic cyclic compound 20576
                                organic heterocyclic compound 19401
                                  oxacycle 17575
                                    benzopyran 10458
                                      1-benzopyran 10180
                                        isoflavonoid 3992
                                          isoflavans 221
                                            isoflavanones 185
                                              (+)-Sophorol 0
                                              (+-)-5-Deoxykievitone 0
                                              (-)-Sophorol 0
                                              3-(1,3-benzodioxol-5-yl)-5,7-dihydroxy-6-(3-methylbut-2-enyl)-1-benzopyran-4-one 0
                                              7-(1,3-benzodioxol-5-yl)-5-methoxy-2,2-dimethyl-6-pyrano[3,2-g][1]benzopyranone 0
                                              Cyclokievitone 0
                                              Deguelin 147
                                              Euchretin A 0
                                              Lachnoisoflavones A, (rac)- 0
                                              Lachnoisoflavones B 0
                                              Licoagroisoflavone 0
                                              Millettone 0
                                              Osajin 36
                                              Pomiferin 33
                                              Sumatrol 0
                                              Toxicarol 0
                                              alpinumisoflavone 14
                                              hydroxyisoflavanone + 5
                                              isoflavanone + 5
                                              methoxyisoflavanone + 5
                                              sophoraisoflavanone B 0
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