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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ethoprophos
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Accession:CHEBI:38665 term browser browse the term
Definition:An organothiophosphate insecticide that has formula C8H19O2PS2.
Synonyms:exact_synonym: O-ethyl S,S-dipropyl phosphorodithioate
 related_synonym: Ethoprop;   Formula=C8H19O2PS2;   InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3;   InChIKey=VJYFKVYYMZPMAB-UHFFFAOYSA-N;   O-ethyl S,S-dipropyl dithiophosphate;   Phosphorodithioic acid, O-ethyl S,S-dipropyl ester;   SMILES=CCCSP(=O)(OCC)SCCC
 xref: Beilstein:8139788;   CAS:13194-48-4;   KEGG:C18687;   LINCS:LSM-2169
 xref_mesh: MESH:C474843
 xref: PPDB:279


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ethoprophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO ethoprop metabolite results in decreased activity of ACHE protein CTD PMID:30625376 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Anxa10 annexin A10 increases expression ISO ethoprophos results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465
JBrowse link
G Arg1 arginase 1 decreases expression ISO ethoprophos results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO ethoprophos results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO ethoprophos results in decreased expression of CYP7A1 mRNA; ethoprophos results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO ethoprophos results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO ethoprophos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      application 19494
        agrochemical 14682
          ethoprophos 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      chalcogen 19454
                        oxygen atom 19415
                          oxygen molecular entity 19415
                            hydroxides 19139
                              oxoacid 18273
                                pnictogen oxoacid 10308
                                  phosphorus oxoacid 9228
                                    phosphoric acids 7945
                                      phosphoric acid 7945
                                        phosphoric acid derivative 7624
                                          phosphate 7624
                                            organic phosphate 7623
                                              organic thiophosphate 2895
                                                ethoprophos 7
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