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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:disulfoton
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Accession:CHEBI:38661 term browser browse the term
Definition:An organic thiophosphate that is the diethyl ester of S-[2-(ethylsulfanyl)ethyl] dihydrogen phosphorodithioate.
Synonyms:exact_synonym: O,O-diethyl S-[2-(ethylsulfanyl)ethyl] dithiophosphate
 related_synonym: Ethylthiometon;   Formula=C8H19O2PS3;   InChI=1S/C8H19O2PS3/c1-4-9-11(12,10-5-2)14-8-7-13-6-3/h4-8H2,1-3H3;   InChIKey=DOFZAZXDOSGAJZ-UHFFFAOYSA-N;   O,O-Diethyl S-(2-(ethylthio)ethyl) dithiophosphate;   O,O-Diethyl S-(2-ethylmercaptoethyl) dithiophosphate;   Phosphorodithioic acid, O,O-diethyl S-(2-(ethylthio)ethyl) ester;   S-[2-(ethylsulfanyl)ethyl] O,O-dimethyl dithiophosphate;   SMILES=CCOP(=S)(OCC)SCCSCC
 xref: Beilstein:1709167;   CAS:298-04-4;   KEGG:C18400
 xref_mesh: MESH:D004222
 xref: PMID:15294458;   PMID:22818267;   PMID:22968680;   PMID:23303564;   Reaxys:1709167;   Wikipedia:Disulfoton

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disulfoton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases expression
decreases activity		 EXP Disulfoton results in decreased expression of ACHE mRNA
Disulfoton results in decreased activity of ACHE protein		 CTD PMID:8856746 PMID:12935443 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP Disulfoton results in decreased expression of CHRM1 mRNA CTD PMID:8856746 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases expression EXP Disulfoton results in decreased expression of CHRM2 mRNA CTD PMID:8856746 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 decreases expression EXP Disulfoton results in decreased expression of CHRM3 mRNA CTD PMID:8856746 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit decreases expression EXP Disulfoton results in decreased expression of CHRNA1 mRNA CTD PMID:12935443 NCBI chr 3:60,445,657...60,460,724
Ensembl chr 3:60,445,666...60,460,724 		JBrowse link
G Eno2 enolase 2 increases expression EXP Disulfoton results in increased expression of ENO2 mRNA CTD PMID:12935443 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
Ensembl chr 9:157,285,179...157,294,047 		JBrowse link
G Eno3 enolase 3 decreases expression EXP Disulfoton results in decreased expression of ENO3 mRNA CTD PMID:12935443 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Disulfoton binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19817
    role 19767
      application 19445
        agrochemical 14667
          disulfoton 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19817
    subatomic particle 19815
      composite particle 19815
        hadron 19815
          baryon 19815
            nucleon 19815
              atomic nucleus 19815
                atom 19815
                  main group element atom 19705
                    p-block element atom 19705
                      chalcogen 19407
                        oxygen atom 19368
                          oxygen molecular entity 19368
                            hydroxides 19094
                              oxoacid 18243
                                pnictogen oxoacid 10301
                                  phosphorus oxoacid 9222
                                    phosphoric acids 7942
                                      phosphoric acid 7942
                                        phosphoric acid derivative 7622
                                          phosphate 7622
                                            organic phosphate 7621
                                              organic thiophosphate 2894
                                                disulfoton 8
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