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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:disulfoton
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Accession:CHEBI:38661 term browser browse the term
Definition:An organic thiophosphate that is the diethyl ester of S-[2-(ethylsulfanyl)ethyl] dihydrogen phosphorodithioate.
Synonyms:exact_synonym: O,O-diethyl S-[2-(ethylsulfanyl)ethyl] dithiophosphate
 related_synonym: Ethylthiometon;   Formula=C8H19O2PS3;   InChI=1S/C8H19O2PS3/c1-4-9-11(12,10-5-2)14-8-7-13-6-3/h4-8H2,1-3H3;   InChIKey=DOFZAZXDOSGAJZ-UHFFFAOYSA-N;   O,O-Diethyl S-(2-(ethylthio)ethyl) dithiophosphate;   O,O-Diethyl S-(2-ethylmercaptoethyl) dithiophosphate;   Phosphorodithioic acid, O,O-diethyl S-(2-(ethylthio)ethyl) ester;   S-[2-(ethylsulfanyl)ethyl] O,O-dimethyl dithiophosphate;   SMILES=CCOP(=S)(OCC)SCCSCC
 xref: Beilstein:1709167;   CAS:298-04-4;   KEGG:C18400
 xref_mesh: MESH:D004222
 xref: PMID:15294458;   PMID:22818267;   PMID:22968680;   PMID:23303564;   Reaxys:1709167;   Wikipedia:Disulfoton



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disulfoton term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases expression
decreases activity
EXP Disulfoton results in decreased expression of ACHE mRNA
Disulfoton results in decreased activity of ACHE protein
CTD PMID:8856746 PMID:12935443 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP Disulfoton results in decreased expression of CHRM1 mRNA CTD PMID:8856746 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases expression EXP Disulfoton results in decreased expression of CHRM2 mRNA CTD PMID:8856746 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 decreases expression EXP Disulfoton results in decreased expression of CHRM3 mRNA CTD PMID:8856746 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit decreases expression EXP Disulfoton results in decreased expression of CHRNA1 mRNA CTD PMID:12935443 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840
JBrowse link
G Eno2 enolase 2 increases expression EXP Disulfoton results in increased expression of ENO2 mRNA CTD PMID:12935443 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Eno3 enolase 3 decreases expression EXP Disulfoton results in decreased expression of ENO3 mRNA CTD PMID:12935443 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Disulfoton binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link

Term paths to the root
Path 1
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  CHEBI ontology 20039
    role 19990
      application 19729
        agrochemical 15211
          disulfoton 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 20039
    subatomic particle 20037
      composite particle 20037
        hadron 20037
          baryon 20037
            nucleon 20037
              atomic nucleus 20037
                atom 20037
                  main group element atom 19938
                    p-block element atom 19938
                      chalcogen 19666
                        oxygen atom 19638
                          oxygen molecular entity 19638
                            hydroxides 19369
                              oxoacid 18670
                                pnictogen oxoacid 10746
                                  phosphorus oxoacid 9742
                                    phosphoric acids 8547
                                      phosphoric acid 8547
                                        phosphoric acid derivative 8249
                                          phosphate 8249
                                            organic phosphate 8248
                                              organic thiophosphate 3819
                                                disulfoton 8
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