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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organochlorine acaricide
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Accession:CHEBI:38657 term browser browse the term
Definition:Any organochlorine pesticide that has been used as an acaricide.
Synonyms:related_synonym: chlororganische Akarizide;   organochloride acaricide;   organochloride acaricides;   organochlorine acaricides



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azamethiphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO
EXP
azamethiphos results in decreased activity of ACHE protein CTD PMID:21251949 PMID:33844597 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA] CTD PMID:28385489 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Gap43 growth associated protein 43 multiple interactions EXP azamethiphos promotes the reaction [NGF protein results in increased expression of GAP43 mRNA] CTD PMID:28385489 NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045
JBrowse link
G Ngf nerve growth factor multiple interactions EXP azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]; azamethiphos promotes the reaction [NGF protein results in increased expression of GAP43 mRNA] CTD PMID:28385489 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
chlorfenvinfos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO
EXP
asoxime chloride inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] CTD PMID:1855619 PMID:2340983 PMID:6933967 PMID:8783813 PMID:16201202 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [Chlorfenvinphos co-treated with ethion co-treated with Linuron] results in increased expression of CYP3A4 mRNA CTD PMID:25028461 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [Chlorfenvinphos co-treated with ethion co-treated with Linuron] results in increased activity of NR1I2 protein CTD PMID:25028461 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
chloropropylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [chloropropylate results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO chloropropylate results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO chloropropylate results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO chloropropylate binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
dichlorvos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity
decreases expression
multiple interactions
decreases response to substance
increases phosphorylation
increases acylation
ISO
EXP
Dichlorvos metabolite results in decreased activity of ACHE protein; Dichlorvos results in decreased activity of ACHE protein
Dichlorvos results in decreased expression of ACHE protein
1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; 1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [Dichlorvos co-treated with Monocrotophos] results in increased activity of ACHE protein; [Monocrotophos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [sodium arsenite co-treated with Dichlorvos co-treated with Monocrotophos] results in decreased activity of ACHE protein; [sodium arsenite co-treated with Dichlorvos] results in decreased activity of ACHE protein; Dichlorvos inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]
ACHE protein results in decreased susceptibility to Dichlorvos
Dichlorvos results in increased phosphorylation of ACHE protein
Dichlorvos results in increased acylation of ACHE protein
[bacoside A co-treated with Plant Preparations] inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; coumarin inhibits the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Dichlorvos binds to and results in decreased activity of ACHE protein; Dichlorvos promotes the reaction [malaoxon results in decreased activity of ACHE protein]; Gallamine Triethiodide affects the reaction [Dichlorvos results in increased acylation of ACHE protein]; Gallamine Triethiodide promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; Propidium promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tubocurarine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]
[Carbaryl co-treated with Dichlorvos] results in decreased activity of ACHE protein; [crotoxyphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Dichlorvos results in increased phosphorylation of ACHE protein] inhibits the reaction [thioflavin T binds to ACHE protein]; [malaoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Mevinphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Paraoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Parathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Phosphamidon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Physostigmine co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Trichlorfon co-treated with Dichlorvos] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Dichlorvos promotes the reaction [Chlorpromazine results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]
CTD PMID:119426 PMID:235931 PMID:473212 PMID:475593 PMID:597376 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization
multiple interactions
EXP Dichlorvos affects the localization of AIFM1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos affects the localization of AIFM1 protein]
CTD PMID:24231740 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Dichlorvos results in increased expression of AKR7A3 mRNA CTD PMID:21813463 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Alb albumin affects binding ISO Dichlorvos binds to ALB protein CTD PMID:15525694 PMID:17188226 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Dichlorvos results in increased expression of ALDH1A1 mRNA CTD PMID:21813463 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Anxa2 annexin A2 increases expression EXP Dichlorvos results in increased expression of ANXA2 mRNA CTD PMID:21813463 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apeh acylaminoacyl-peptide hydrolase decreases activity ISO
EXP
Dichlorvos results in decreased activity of APEH protein CTD PMID:15888665 PMID:19379766 NCBI chr 8:108,773,791...108,782,903
Ensembl chr 8:108,773,794...108,782,933
JBrowse link
G App amyloid beta precursor protein increases secretion ISO
EXP
Dichlorvos results in increased secretion of APP protein alternative form
Dichlorvos results in increased secretion of APP protein modified form
CTD PMID:7605915 PMID:8624119 PMID:11526466 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ar androgen receptor multiple interactions ISO Dichlorvos promotes the reaction [Metribolone results in increased activity of AR protein] CTD PMID:17219378 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ATM mRNA]
Dichlorvos results in increased expression of ATM mRNA; Dichlorvos results in increased expression of ATM protein
CTD PMID:24369695 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Dichlorvos results in increased expression of BAX protein CTD PMID:22817663 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases expression
decreases activity
ISO
EXP
[Dichlorvos results in decreased activity of BCHE protein] which results in increased susceptibility to Succinylcholine; Dichlorvos binds to and results in decreased activity of BCHE protein; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]
Dichlorvos results in decreased expression of BCHE protein
diacetylmonoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Magnesium Sulfate promotes the reaction [Dichlorvos results in decreased activity of BCHE protein]
[bacoside A co-treated with Plant Preparations] inhibits the reaction [Dichlorvos results in decreased expression of BCHE protein]; Dichlorvos binds to and results in decreased activity of BCHE protein
CTD PMID:235931 PMID:423703 PMID:1276991 PMID:4631366 PMID:7150809 More... NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Dichlorvos results in increased expression of BTG2 mRNA CTD PMID:21813463 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Casp1 caspase 1 increases expression EXP Dichlorvos results in increased expression of CASP1 mRNA CTD PMID:23053939 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
increases expression
decreases expression
multiple interactions
ISO
EXP
Dichlorvos results in increased activity of CASP3 protein
Dichlorvos results in increased cleavage of CASP3 protein
Dichlorvos results in increased expression of CASP3 mRNA
Dichlorvos results in decreased expression of CASP3 mRNA
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; Dichlorvos results in increased cleavage of and results in increased activity of CASP3 protein; TEMPOL-H inhibits the reaction [Dichlorvos results in increased cleavage of CASP3 protein]
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]
CTD PMID:16973328 PMID:17681413 PMID:17850875 PMID:19815060 PMID:21784090 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
EXP [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein] CTD PMID:16973328 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
increases activity
decreases activity
EXP
ISO
[Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of CAT protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of CAT protein; [Phorate co-treated with acephate co-treated with Dichlorvos co-treated with Dimethoate] results in decreased activity of CAT protein; Acetylcysteine inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; coenzyme Q10 inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]
Dichlorvos results in increased activity of CAT protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]
CTD PMID:1587340 PMID:20302853 PMID:22034174 PMID:22224058 PMID:22751200 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cdc25a cell division cycle 25A increases expression
multiple interactions
EXP Dichlorvos results in increased expression of CDC25A mRNA; Dichlorvos results in increased expression of CDC25A protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDC25A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDC25A protein]
CTD PMID:24369695 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
EXP Dichlorvos results in increased expression of CDKN1A mRNA; Dichlorvos results in increased expression of CDKN1A protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A protein]
CTD PMID:21813463 PMID:24369695 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Dichlorvos results in increased expression of CES2 mRNA CTD PMID:21813463 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Chat choline O-acetyltransferase increases activity EXP Dichlorvos results in increased activity of CHAT protein CTD PMID:17722737 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 protein]
Dichlorvos results in increased expression of CHEK2 mRNA; Dichlorvos results in increased expression of CHEK2 protein
CTD PMID:24369695 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP Dichlorvos results in decreased expression of CHRM1 protein CTD PMID:19100812 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases expression EXP Dichlorvos results in decreased expression of CHRM2 protein CTD PMID:19100812 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 decreases expression EXP Dichlorvos results in decreased expression of CHRM3 protein CTD PMID:19100812 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Dichlorvos inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:15733544 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Dichlorvos inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:15733544 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases activity
ISO Dichlorvos inhibits the reaction [CP 55244 binds to CNR1 protein]
Dichlorvos results in decreased activity of CNR1 protein
CTD PMID:12243867 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation EXP Dichlorvos results in decreased phosphorylation of CREB1 protein CTD PMID:19100812 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression EXP Dichlorvos results in increased expression of CYBB mRNA; Dichlorvos results in increased expression of CYBB protein CTD PMID:21964614 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
EXP Dichlorvos affects the localization of CYCS protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [Dichlorvos affects the localization of CYCS protein]
CTD PMID:17850875 PMID:21784090 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Dbh dopamine beta-hydroxylase increases activity
multiple interactions
EXP Dichlorvos results in increased activity of DBH protein
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of DBH protein]
CTD PMID:12186780 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 affects response to substance ISO DLG2 gene SNP affects the susceptibility to Dichlorvos CTD PMID:25622337 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475
JBrowse link
G Drd2 dopamine receptor D2 decreases activity
multiple interactions
EXP Dichlorvos results in decreased activity of DRD2 protein
Nimodipine inhibits the reaction [Dichlorvos results in decreased activity of DRD2 protein]
CTD PMID:12186780 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Esr1 estrogen receptor 1 decreases activity ISO Dichlorvos results in decreased activity of ESR1 protein CTD PMID:22562034 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Dichlorvos results in decreased expression of FAS protein CTD PMID:15369847 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand decreases expression ISO Dichlorvos results in decreased expression of FASL protein CTD PMID:15369847 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta decreases expression EXP Dichlorvos results in decreased expression of GABRD mRNA CTD PMID:19146868 NCBI chr 5:165,958,508...165,970,407
Ensembl chr 5:165,958,484...165,970,411
JBrowse link
G Gck glucokinase decreases activity
increases expression
EXP Dichlorvos results in decreased activity of GCK protein
Dichlorvos results in increased expression of GCK mRNA
CTD PMID:16153661 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
increases activity
decreases activity
multiple interactions
EXP Dichlorvos results in decreased expression of GSR protein
Dichlorvos results in increased activity of GSR protein
Dichlorvos results in decreased activity of GSR protein
[Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of GSR protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of GSR protein; Dichlorvos inhibits the reaction [sodium arsenite results in increased activity of GSR protein]; Plant Extracts inhibits the reaction [Dichlorvos results in decreased activity of GSR protein]; sodium arsenite inhibits the reaction [Dichlorvos results in increased activity of GSR protein]
CTD PMID:18539328 PMID:20302853 PMID:22224058 PMID:22751200 PMID:25895260 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gys2 glycogen synthase 2 increases activity EXP Dichlorvos results in increased activity of GYS2 protein CTD PMID:222008 NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228
JBrowse link
G Gzma granzyme A decreases expression ISO Dichlorvos results in decreased expression of GZMA mRNA; Dichlorvos results in decreased expression of GZMA protein CTD PMID:16002202 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G Gzmb granzyme B decreases expression ISO Dichlorvos results in decreased expression of GZMB protein CTD PMID:18063463 NCBI chr15:30,343,361...30,346,792 JBrowse link
G Gzmk granzyme K decreases expression ISO Dichlorvos results in decreased expression of GZMK protein CTD PMID:18063463 NCBI chr 2:44,840,811...44,848,829
Ensembl chr 2:44,840,811...44,848,894
JBrowse link
G Hdc histidine decarboxylase increases activity EXP Dichlorvos results in increased activity of HDC protein CTD PMID:119426 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hk1 hexokinase 1 decreases activity EXP Dichlorvos results in decreased activity of HK1 protein CTD PMID:10544956 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO Dichlorvos results in decreased expression of HMOX1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of HMOX1 protein]
CTD PMID:26814074 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma decreases expression EXP Dichlorvos results in decreased expression of IFNG protein CTD PMID:19145326 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion
EXP Dichlorvos results in increased expression of IL1B mRNA; Dichlorvos results in increased expression of IL1B protein
Dichlorvos results in increased secretion of IL1B protein
CTD PMID:21964614 PMID:22817663 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 decreases response to substance ISO Dichlorvos results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il6 interleukin 6 increases expression EXP Dichlorvos results in increased expression of IL6 mRNA; Dichlorvos results in increased expression of IL6 protein CTD PMID:21964614 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
EXP Dichlorvos results in increased expression of ITGAM mRNA; Dichlorvos results in increased expression of ITGAM protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ITGAM protein]
CTD PMID:21964614 PMID:22817663 PMID:24369695 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Lcat lecithin cholesterol acyltransferase decreases activity
multiple interactions
ISO Dichlorvos results in decreased activity of LCAT protein
Dichlorvos inhibits the reaction [[LCAT protein results in increased metabolism of Lecithins] which results in increased chemical synthesis of Cholesterol Esters]
CTD PMID:4847537 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lpl lipoprotein lipase decreases activity EXP Dichlorvos results in decreased activity of LPL protein CTD PMID:3196159 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Maoa monoamine oxidase A decreases activity EXP Dichlorvos results in decreased activity of MAOA protein CTD PMID:12018584 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases activity EXP Dichlorvos results in decreased activity of MAOB protein CTD PMID:12018584 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
increases phosphorylation
EXP Nimodipine inhibits the reaction [Dichlorvos results in increased phosphorylation of MAP2 protein] CTD PMID:11282359 PMID:16635102 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP Dichlorvos results in increased expression of MGMT mRNA CTD PMID:21813463 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 affects expression
decreases activity
EXP
ISO
Dichlorvos affects the expression of NCEH1 protein modified form
Dichlorvos results in decreased activity of NCEH1 protein
CTD PMID:6245657 PMID:16978018 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Dichlorvos affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nefl neurofilament light chain decreases expression EXP Dichlorvos results in decreased expression of NEFL mRNA CTD PMID:19146868 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity
decreases expression
multiple interactions
ISO Dichlorvos results in increased activity of NFE2L2 protein
Dichlorvos results in decreased expression of NFE2L2 mRNA; Dichlorvos results in decreased expression of NFE2L2 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 protein]
CTD PMID:20143881 PMID:25891459 PMID:26814074 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
EXP Dichlorvos results in increased expression of NOS2 mRNA; Dichlorvos results in increased expression of NOS2 protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of NOS2 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of NOS2 protein]
CTD PMID:22817663 PMID:24369695 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO Dichlorvos results in decreased expression of NQO1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NQO1 protein]
CTD PMID:26814074 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases activity
increases cleavage
multiple interactions
EXP Dichlorvos results in increased activity of PARP1 protein
Dichlorvos results in increased cleavage of PARP1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in increased activity of PARP1 protein]
CTD PMID:24231740 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases activity ISO
EXP
Dichlorvos results in decreased activity of PNPLA6 protein CTD PMID:7713347 PMID:9268605 PMID:9586870 PMID:10776595 PMID:11282359 More... NCBI chr12:1,574,387...1,603,735
Ensembl chr12:1,560,363...1,603,734
JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases secretion
EXP Dichlorvos inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones]
Dichlorvos results in increased secretion of POMC protein modified form
CTD PMID:2993719 PMID:6245657 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
decreases expression
decreases response to substance
EXP
ISO
1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)but-2-ene inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; asoxime chloride inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]
Dichlorvos results in decreased expression of PON1 mRNA; Dichlorvos results in decreased expression of PON1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of HMOX1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NQO1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of PON1 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of PON1 protein]
PON1 protein results in decreased susceptibility to Dichlorvos
CTD PMID:20412842 PMID:25891459 PMID:26814074 PMID:29098328 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Prf1 perforin 1 decreases expression ISO Dichlorvos results in decreased expression of PRF1 mRNA; Dichlorvos results in decreased expression of PRF1 protein CTD PMID:16002202 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of PRKDC mRNA]
Dichlorvos results in increased expression of PRKDC mRNA; Dichlorvos results in increased expression of PRKDC protein
CTD PMID:24369695 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Pygb glycogen phosphorylase B increases activity EXP Dichlorvos results in increased activity of PYGB protein CTD PMID:10544956 NCBI chr 3:139,611,724...139,658,521
Ensembl chr 3:139,611,749...139,663,553
JBrowse link
G Pygl glycogen phosphorylase L increases activity EXP Dichlorvos results in increased activity of PYGL protein CTD PMID:222008 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Snca synuclein alpha multiple interactions
affects localization
EXP coenzyme Q10 inhibits the reaction [Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]]; Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]
Dichlorvos affects the localization of SNCA protein
CTD PMID:21073741 PMID:21843543 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases activity
EXP [10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide results in increased expression of SOD2 protein] which results in decreased susceptibility to Dichlorvos; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of SOD2 protein] CTD PMID:17850875 PMID:21784090 PMID:24231740 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression EXP Dichlorvos results in increased expression of TAP1 mRNA CTD PMID:21813463 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tat tyrosine aminotransferase multiple interactions
increases expression
EXP [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tf transferrin affects binding ISO Dichlorvos binds to TF protein
Dichlorvos binds to TRF protein
CTD PMID:18930948 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Th tyrosine hydroxylase increases activity
multiple interactions
EXP Dichlorvos results in increased activity of TH protein
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein]
CTD PMID:12186780 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tnf tumor necrosis factor increases expression
increases secretion
EXP Dichlorvos results in increased expression of TNF mRNA; Dichlorvos results in increased expression of TNF protein
Dichlorvos results in increased secretion of TNF protein
CTD PMID:21964614 PMID:22817663 PMID:23053939 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 decreases expression
increases expression
multiple interactions
EXP Dichlorvos results in decreased expression of TP53 mRNA
Dichlorvos results in increased expression of TP53 mRNA; Dichlorvos results in increased expression of TP53 protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 protein]
CTD PMID:23053939 PMID:24369695 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tubb5 tubulin, beta 5 class I increases phosphorylation EXP Dichlorvos results in increased phosphorylation of TUBB protein CTD PMID:11282359 PMID:16635102 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 decreases activity EXP Dichlorvos results in decreased activity of UGP2 protein CTD PMID:222008 NCBI chr14:95,456,330...95,497,483
Ensembl chr14:95,456,330...95,496,830
JBrowse link
G Xab2 XPA binding protein 2 affects response to substance ISO XAB2 gene SNP affects the susceptibility to Dichlorvos CTD PMID:22102698 NCBI chr12:1,667,672...1,679,702
Ensembl chr12:1,667,672...1,679,692
JBrowse link
dicofol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding
multiple interactions
ISO Dicofol binds to AR protein
Dicofol inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Dicofol inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [Dicofol results in increased activity of AR protein]
CTD PMID:15064155 PMID:15253041 PMID:18324785 PMID:21310686 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Dicofol results in decreased activity of CYP19A1 protein CTD PMID:10806373 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP1A1 mRNA; Dicofol results in increased expression of CYP1A1 protein CTD PMID:19595748 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP Dicofol results in increased expression of CYP1A2 mRNA CTD PMID:19595748 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP2B1 protein CTD PMID:19595748 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Dicofol results in increased expression of CYP2B2 protein CTD PMID:19595748 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP2E1 protein CTD PMID:19595748 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP3A23-3A1 mRNA CTD PMID:19595748 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Dicofol results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
increases activity
ISO Dicofol binds to ESR1 protein
Dicofol binds to and results in increased activity of ESR1 protein
Dicofol results in increased activity of ESR1 protein
CTD PMID:10789375 PMID:15064155 PMID:15253041 PMID:16337670 PMID:29162470 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO Dicofol results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases activity EXP Dicofol results in increased activity of GGT1 protein CTD PMID:2387028 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP Dicofol results in increased activity of GPT protein CTD PMID:2387028 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Dicofol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Dicofol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Dicofol inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Dicofol binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Dicofol results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Prkcb protein kinase C, beta multiple interactions
increases activity
ISO Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein]; Phosphatidylserines promotes the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Ttr transthyretin affects binding EXP Dicofol binds to TTR protein CTD PMID:2043046 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
fluvalinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO fluvalinate analog promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:25684042 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cdk2 cyclin dependent kinase 2 affects binding ISO fluvalinate binds to CDK2 protein CTD PMID:32278787 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects binding ISO fluvalinate binds to CYP3A4 protein CTD PMID:32278787 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects binding ISO fluvalinate binds to ERBB2 protein CTD PMID:32278787 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO fluvalinate binds to FGFR2 protein CTD PMID:32278787 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects binding ISO fluvalinate binds to MMP9 protein CTD PMID:32278787 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 affects binding ISO fluvalinate binds to NQO1 protein CTD PMID:32278787 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO fluvalinate inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO fluvalinate binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO fluvalinate binds to PPARD protein CTD PMID:32278787 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO fluvalinate binds to RORA protein CTD PMID:32278787 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO fluvalinate binds to RORC protein CTD PMID:32278787 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
pyridaben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco2 aconitase 2 decreases activity EXP pyridaben results in decreased activity of ACO2 protein CTD PMID:26141520 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 increases expression ISO pyridaben results in increased expression of ADAM22 mRNA CTD PMID:22563483 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases expression ISO pyridaben results in increased expression of ADCYAP1 mRNA CTD PMID:22563483 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Ago3 argonaute RISC catalytic component 3 increases expression ISO pyridaben results in increased expression of AGO3 mRNA CTD PMID:22563483 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230
JBrowse link
G Amn amnion associated transmembrane protein decreases expression ISO pyridaben results in decreased expression of AMN mRNA CTD PMID:22563483 NCBI chr 6:130,311,372...130,318,815
Ensembl chr 6:130,311,372...130,318,815
JBrowse link
G Ar androgen receptor multiple interactions ISO pyridaben inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:30818834 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atoh7 atonal bHLH transcription factor 7 decreases expression ISO pyridaben results in decreased expression of ATOH7 mRNA CTD PMID:22563483 NCBI chr20:25,530,826...25,531,275
Ensembl chr20:25,530,826...25,531,275
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
multiple interactions
ISO BCL2 protein results in decreased susceptibility to pyridaben
PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to pyridaben]
CTD PMID:12730627 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO pyridaben results in increased expression of BCL2A1 mRNA CTD PMID:22563483 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bicd1 BICD cargo adaptor 1 increases expression ISO pyridaben results in increased expression of BICD1 mRNA CTD PMID:22563483 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434
JBrowse link
G C2cd4d C2 calcium-dependent domain containing 4D decreases expression ISO pyridaben results in decreased expression of C2CD4D mRNA CTD PMID:22563483 NCBI chr 2:181,997,393...182,001,938
Ensembl chr 2:181,997,078...182,002,087
JBrowse link
G Cabyr calcium binding tyrosine phosphorylation regulated increases expression ISO pyridaben results in increased expression of CABYR mRNA CTD PMID:22563483 NCBI chr18:3,892,062...3,904,391
Ensembl chr18:3,892,132...3,903,840
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases expression ISO pyridaben results in increased expression of CACNA1E mRNA CTD PMID:22563483 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450
JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression ISO pyridaben results in increased expression of CAMP mRNA CTD PMID:22563483 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
JBrowse link
G Capn11 calpain 11 decreases expression ISO pyridaben results in decreased expression of CAPN11 mRNA CTD PMID:22563483 NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601
JBrowse link
G Ccdc88a coiled coil domain containing 88A increases expression ISO pyridaben results in increased expression of CCDC88A mRNA CTD PMID:22563483 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO pyridaben results in increased expression of CCL19 mRNA CTD PMID:22563483 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 increases expression ISO pyridaben results in increased expression of CCL21A mRNA CTD PMID:22563483 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686
JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression ISO pyridaben results in decreased expression of CDHR4 mRNA CTD PMID:22563483 NCBI chr 8:108,682,594...108,690,358 JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO pyridaben results in decreased expression of CEBPD mRNA CTD PMID:22563483 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO pyridaben results in increased expression of CEP290 mRNA CTD PMID:22563483 NCBI chr 7:35,310,071...35,399,392
Ensembl chr 7:35,310,199...35,399,392
JBrowse link
G Cldn3 claudin 3 decreases expression ISO pyridaben results in decreased expression of CLDN3 mRNA CTD PMID:22563483 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Crlf2 cytokine receptor-like factor 2 decreases expression ISO pyridaben results in decreased expression of CRLF2 mRNA CTD PMID:22563483 NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642
JBrowse link
G Dgki diacylglycerol kinase, iota increases expression ISO pyridaben results in increased expression of DGKI mRNA CTD PMID:22563483 NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733
JBrowse link
G Dip2b disco-interacting protein 2 homolog B increases expression ISO pyridaben results in increased expression of DIP2B mRNA CTD PMID:22563483 NCBI chr 7:131,174,575...131,350,417
Ensembl chr 7:131,174,567...131,349,092
JBrowse link
G Dmrta2 DMRT-like family A2 decreases expression ISO pyridaben results in decreased expression of DMRTA2 mRNA CTD PMID:22563483 NCBI chr 5:124,805,883...124,811,694
Ensembl chr 5:124,805,883...124,811,630
JBrowse link
G Drd4 dopamine receptor D4 decreases expression ISO pyridaben results in decreased expression of DRD4 mRNA CTD PMID:22563483 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Egr4 early growth response 4 decreases expression ISO pyridaben results in decreased expression of EGR4 mRNA CTD PMID:22563483 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328
JBrowse link
G Elane elastase, neutrophil expressed increases expression ISO pyridaben results in increased expression of ELANE mRNA CTD PMID:22563483 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100
JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
ISO pyridaben results in increased activity of ESR1 protein
pyridaben binds to and results in increased activity of ESR1 protein; pyridaben inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
CTD PMID:20143881 PMID:30818834 PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO pyridaben inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:30818834 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO pyridaben inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]; pyridaben inhibits the reaction [XCT790 results in decreased activity of ESRRA protein] CTD PMID:30818834 NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268
JBrowse link
G Etl4 enhancer trap locus 4 increases expression ISO pyridaben results in increased expression of ETL4 mRNA CTD PMID:22563483 NCBI chr17:82,841,075...83,304,868
Ensembl chr17:82,495,041...83,304,715
JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO pyridaben results in decreased expression of H2BC9 mRNA CTD PMID:22563483 NCBI chr17:42,470,593...42,478,605 JBrowse link
G H3c1 H3 clustered histone 1 decreases expression ISO pyridaben results in decreased expression of H3C1 mRNA CTD PMID:22563483 NCBI chr17:41,367,824...41,368,902 JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP zinc chloride inhibits the reaction [pyridaben results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hmx3 H6 family homeobox 3 decreases expression ISO pyridaben results in decreased expression of HMX3 mRNA CTD PMID:22563483 NCBI chr 1:186,313,237...186,315,201
Ensembl chr 1:186,313,063...186,315,201
JBrowse link
G Hs3st6 heparan sulfate-glucosamine 3-sulfotransferase 6 decreases expression ISO pyridaben results in decreased expression of HS3ST6 mRNA CTD PMID:22563483 NCBI chr10:13,781,999...13,788,133
Ensembl chr10:13,781,993...13,788,133
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO pyridaben results in decreased expression of IDH3A mRNA CTD PMID:30818834 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO pyridaben results in increased expression of INHBA mRNA CTD PMID:22563483 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Insl3 insulin-like 3 decreases expression ISO pyridaben results in decreased expression of INSL3 mRNA CTD PMID:22563483 NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
JBrowse link
G Itgb8 integrin subunit beta 8 increases expression ISO pyridaben results in increased expression of ITGB8 mRNA CTD PMID:22563483 NCBI chr 6:140,124,997...140,208,254
Ensembl chr 6:140,127,203...140,208,476
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 increases expression ISO pyridaben results in increased expression of KCNA2 mRNA CTD PMID:22563483 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 increases expression ISO pyridaben results in increased expression of KCNMA1 mRNA CTD PMID:22563483 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kif1b kinesin family member 1B increases expression ISO pyridaben results in increased expression of KIF1B mRNA CTD PMID:22563483 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Klf2 Kruppel-like factor 2 decreases expression ISO pyridaben results in decreased expression of KLF2 mRNA CTD PMID:22563483 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Klhl15 kelch-like family member 15 increases expression ISO pyridaben results in increased expression of KLHL15 mRNA CTD PMID:22563483 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO pyridaben results in increased expression of LAMC2 mRNA CTD PMID:22563483 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lifr LIF receptor subunit alpha increases expression ISO pyridaben results in increased expression of LIFR mRNA CTD PMID:22563483 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699
JBrowse link
G Lrp4 LDL receptor related protein 4 increases expression ISO pyridaben results in increased expression of LRP4 mRNA CTD PMID:22563483 NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593
JBrowse link
G Lrrc63 leucine rich repeat containing 63 decreases expression ISO pyridaben results in decreased expression of LRRC63 mRNA CTD PMID:22563483 NCBI chr15:50,400,199...50,437,321
Ensembl chr15:50,400,200...50,437,321
JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 decreases expression ISO pyridaben results in decreased expression of LTB4R2 mRNA CTD PMID:22563483 NCBI chr15:29,258,427...29,260,340
Ensembl chr15:29,259,240...29,260,316
JBrowse link
G Ltf lactotransferrin increases expression ISO pyridaben results in increased expression of LTF mRNA CTD PMID:22563483 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 decreases expression ISO pyridaben results in decreased expression of MAPK15 mRNA CTD PMID:22563483 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645
JBrowse link
G Marchf9 membrane associated ring-CH-type finger 9 decreases expression ISO pyridaben results in decreased expression of MARCHF9 mRNA CTD PMID:22563483 NCBI chr 7:62,879,017...62,882,495 JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 increases expression ISO pyridaben results in increased expression of MBOAT2 mRNA CTD PMID:22563483 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485
JBrowse link
G Mdfi MyoD family inhibitor decreases expression ISO pyridaben results in decreased expression of MDFI mRNA CTD PMID:22563483 NCBI chr 9:13,156,806...13,175,218
Ensembl chr 9:13,156,866...13,175,217
JBrowse link
G Mpo myeloperoxidase increases expression ISO pyridaben results in increased expression of MPO mRNA CTD PMID:22563483 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrtfb myocardin related transcription factor B increases expression ISO pyridaben results in increased expression of MRTFB mRNA CTD PMID:22563483 NCBI chr10:1,116,315...1,278,106 JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming increases expression ISO pyridaben results in increased expression of MUC6 mRNA CTD PMID:22563483 NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842
JBrowse link
G Myoc myocilin increases expression ISO pyridaben results in increased expression of MYOC mRNA CTD PMID:22563483 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO pyridaben results in increased expression of NFAT5 mRNA CTD PMID:22563483 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO pyridaben results in increased activity of NFE2L2 protein CTD PMID:30818834 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfib nuclear factor I/B increases expression ISO pyridaben results in increased expression of NFIB mRNA CTD PMID:22563483 NCBI chr 5:96,759,208...96,973,092
Ensembl chr 5:96,764,653...96,975,479
JBrowse link
G Nipbl NIPBL, cohesin loading factor increases expression ISO pyridaben results in increased expression of NIPBL mRNA CTD PMID:22563483 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 decreases response to substance ISO NMNAT3 protein results in decreased susceptibility to pyridaben CTD PMID:18463239 NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645
JBrowse link
G Nps neuropeptide S increases expression ISO pyridaben results in increased expression of NPS mRNA CTD PMID:22563483 NCBI chr 1:190,077,040...190,080,821
Ensembl chr 1:190,077,040...190,080,821
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO pyridaben binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO pyridaben results in decreased expression of NR4A1 mRNA CTD PMID:22563483 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases activity
ISO pyridaben inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]
pyridaben results in increased activity of ODC1 protein
CTD PMID:9834970 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide decreases expression ISO pyridaben results in decreased expression of OXT mRNA CTD PMID:22563483 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490
JBrowse link
G Park7 Parkinsonism associated deglycase decreases response to substance ISO PARK7 protein results in decreased susceptibility to pyridaben CTD PMID:21219333 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO pyridaben results in increased cleavage of PARP1 protein
[pyridaben co-treated with Paraquat] results in increased cleavage of PARP1 protein
CTD PMID:16237197 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pgr progesterone receptor multiple interactions ISO pyridaben inhibits the reaction [Promegestone results in increased activity of PGR protein] CTD PMID:30818834 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link
G Phox2a paired-like homeobox 2a decreases expression ISO pyridaben results in decreased expression of PHOX2A mRNA CTD PMID:22563483 NCBI chr 1:156,178,754...156,183,118
Ensembl chr 1:156,178,754...156,183,118
JBrowse link
G Plce1 phospholipase C, epsilon 1 increases expression ISO pyridaben results in increased expression of PLCE1 mRNA CTD PMID:22563483 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO pyridaben binds to and results in increased activity of PPARG protein; pyridaben inhibits the reaction [Rosiglitazone results in increased activity of PPARG protein] CTD PMID:30818834 PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions
ISO pyridaben results in increased expression of PPARGC1A mRNA
pyridaben inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]
CTD PMID:22563483 PMID:30818834 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Prr7 proline rich 7 (synaptic) decreases expression ISO pyridaben results in decreased expression of PRR7 mRNA CTD PMID:22563483 NCBI chr17:9,164,375...9,173,669
Ensembl chr17:9,165,269...9,172,536
JBrowse link
G Retnlb resistin like beta increases expression ISO pyridaben results in increased expression of RETNLB mRNA CTD PMID:22563483 NCBI chr11:51,983,482...51,985,368
Ensembl chr11:51,983,483...51,985,368
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 increases expression ISO pyridaben results in increased expression of ROCK1 mRNA CTD PMID:22563483 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO pyridaben results in increased expression of S100A8 mRNA CTD PMID:22563483 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO pyridaben results in increased expression of S100A9 mRNA CTD PMID:22563483 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Shox2 short stature homeobox 2 decreases expression ISO pyridaben results in decreased expression of SHOX2 mRNA CTD PMID:22563483 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143
JBrowse link
G Slc8a1 solute carrier family 8 member A1 increases expression ISO pyridaben results in increased expression of SLC8A1 mRNA CTD PMID:22563483 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 increases expression ISO pyridaben results in increased expression of SMOC2 mRNA CTD PMID:22563483 NCBI chr 1:55,262,472...55,391,804
Ensembl chr 1:55,262,530...55,391,693
JBrowse link
G Snca synuclein alpha increases response to substance ISO SNCA protein results in increased susceptibility to pyridaben CTD PMID:16239214 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO pyridaben results in decreased expression of SOCS1 mRNA CTD PMID:22563483 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Ston2 stonin 2 increases expression ISO pyridaben results in increased expression of STON2 mRNA CTD PMID:22563483 NCBI chr 6:110,567,485...110,676,376
Ensembl chr 6:110,567,485...110,676,376
JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression ISO pyridaben results in increased expression of STRBP mRNA CTD PMID:22563483 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949
JBrowse link
G Tbck TBC1 domain containing kinase increases expression ISO pyridaben results in increased expression of TBCK mRNA CTD PMID:22563483 NCBI chr 2:221,175,749...221,348,126
Ensembl chr 2:221,175,785...221,348,126
JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO pyridaben results in decreased expression of TCF15 mRNA CTD PMID:22563483 NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO pyridaben binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Tmem42 transmembrane protein 42 decreases expression ISO pyridaben results in decreased expression of TMEM42 mRNA CTD PMID:22563483 NCBI chr 8:122,674,793...122,677,290
Ensembl chr 8:122,674,070...122,677,276
JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression ISO pyridaben results in increased expression of TNNT2 mRNA CTD PMID:22563483 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 increases expression ISO pyridaben results in increased expression of TRPM3 mRNA CTD PMID:22563483 NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
JBrowse link
G Tusc1 tumor suppressor candidate 1 decreases expression ISO pyridaben results in decreased expression of TUSC1 mRNA CTD PMID:22563483 NCBI chr 5:108,089,952...108,091,636 JBrowse link
G Ubxn7 UBX domain protein 7 increases expression ISO pyridaben results in increased expression of UBXN7 mRNA CTD PMID:22563483 NCBI chr11:68,427,896...68,460,100 JBrowse link
G Ucn urocortin decreases expression ISO pyridaben results in decreased expression of UCN mRNA CTD PMID:22563483 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
G Unc13c unc-13 homolog C increases expression ISO pyridaben results in increased expression of UNC13C mRNA CTD PMID:22563483 NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223
JBrowse link
G Vdr vitamin D receptor increases activity ISO pyridaben results in increased activity of VDR protein CTD PMID:20143881 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Zbtb44 zinc finger and BTB domain containing 44 increases expression ISO pyridaben results in increased expression of ZBTB44 mRNA CTD PMID:22563483 NCBI chr 8:29,466,055...29,524,027
Ensembl chr 8:29,466,352...29,518,163
JBrowse link
G Zfp580 zinc finger protein 580 decreases expression ISO pyridaben results in decreased expression of ZFP580 mRNA CTD PMID:22563483 NCBI chr 1:68,787,118...68,789,286
Ensembl chr 1:68,787,118...68,789,286
JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 increases expression ISO pyridaben results in increased expression of ZHX3 mRNA CTD PMID:22563483 NCBI chr 3:149,417,843...149,548,671
Ensembl chr 3:149,417,818...149,527,079
JBrowse link
tetradifon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 increases activity ISO tetradifon results in increased activity of ESR1 protein CTD PMID:26139245 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO tetradifon results in increased activity of ESR2 protein CTD PMID:26139245 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        pesticide 17134
          organochlorine pesticide 6350
            organochlorine acaricide 212
              azamethiphos 5
              benzoximate 0
              chlorfenapyr 0
              chlorfenvinfos 3
              chloropropylate 4
              clofentezine 0
              dichlorvos 83
              dicofol 20
              fluazuron 0
              flumethrin 0
              fluvalinate + 12
              hexythiazox + 0
              pyridaben 104
              spirodiclofen 0
              tetradifon 2
              tralopyril + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organohalogen compound 17938
                                organochlorine compound 17755
                                  organochlorine pesticide 6350
                                    organochlorine acaricide 212
                                      azamethiphos 5
                                      benzoximate 0
                                      chlorfenapyr 0
                                      chlorfenvinfos 3
                                      chloropropylate 4
                                      clofentezine 0
                                      dichlorvos 83
                                      dicofol 20
                                      fluazuron 0
                                      flumethrin 0
                                      fluvalinate + 12
                                      hexythiazox + 0
                                      pyridaben 104
                                      spirodiclofen 0
                                      tetradifon 2
                                      tralopyril + 0
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