Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organochlorine acaricide
go back to main search page
Accession:CHEBI:38657 term browser browse the term
Definition:Any organochlorine pesticide that has been used as an acaricide.
Synonyms:related_synonym: chlororganische Akarizide;   organochloride acaricide;   organochloride acaricides;   organochlorine acaricides


show annotations for term's descendants           Sort by:
 
azamethiphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO
EXP
azamethiphos results in decreased activity of ACHE protein CTD PMID:21251949 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA] CTD PMID:28385489 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta multiple interactions EXP azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA] CTD PMID:28385489 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Gap43 growth associated protein 43 multiple interactions EXP azamethiphos promotes the reaction [NGF protein results in increased expression of GAP43 mRNA] CTD PMID:28385489 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Ngf nerve growth factor multiple interactions EXP azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]; azamethiphos promotes the reaction [NGF protein results in increased expression of GAP43 mRNA] CTD PMID:28385489 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
chlorfenvinfos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO
EXP
asoxime chloride inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Chlorfenvinphos results in decreased activity of ACHE protein] CTD PMID:1855619, PMID:2340983, PMID:6933967, PMID:8783813, PMID:16201202 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [Chlorfenvinphos co-treated with ethion co-treated with Linuron] results in increased activity of NR1I2 protein CTD PMID:25028461 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
chloropropylate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO Dihydrotestosterone inhibits the reaction [chloropropylate results in increased activity of AR protein] CTD PMID:15064155 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO chloropropylate results in increased activity of ESR1 protein CTD PMID:15064155 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO chloropropylate results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO chloropropylate binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
dichlorvos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity
decreases expression
multiple interactions
decreases response to substance
increases phosphorylation
increases acylation
ISO
EXP
Dichlorvos metabolite results in decreased activity of ACHE protein; Dichlorvos results in decreased activity of ACHE protein
Dichlorvos results in decreased expression of ACHE protein
1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; 1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [Dichlorvos co-treated with Monocrotophos] results in increased activity of ACHE protein; [Monocrotophos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [sodium arsenite co-treated with Dichlorvos co-treated with Monocrotophos] results in decreased activity of ACHE protein; [sodium arsenite co-treated with Dichlorvos] results in decreased activity of ACHE protein; Dichlorvos inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]
ACHE protein results in decreased susceptibility to Dichlorvos
Dichlorvos results in increased phosphorylation of ACHE protein
Dichlorvos results in increased acylation of ACHE protein
[bacoside A co-treated with Plant Preparations] inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; coumarin inhibits the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Dichlorvos binds to and results in decreased activity of ACHE protein; Dichlorvos promotes the reaction [malaoxon results in decreased activity of ACHE protein]; Gallamine Triethiodide affects the reaction [Dichlorvos results in increased acylation of ACHE protein]; Gallamine Triethiodide promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; Propidium promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tubocurarine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]
[Carbaryl co-treated with Dichlorvos] results in decreased activity of ACHE protein; [crotoxyphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Dichlorvos results in increased phosphorylation of ACHE protein] inhibits the reaction [thioflavin T binds to ACHE protein]; [malaoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Mevinphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Paraoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Parathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Phosphamidon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Physostigmine co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Trichlorfon co-treated with Dichlorvos] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Dichlorvos promotes the reaction [Chlorpromazine results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]
CTD PMID:119426, PMID:235931, PMID:473212, PMID:475593, PMID:597376, PMID:1258061, PMID:1494302, PMID:1609424, PMID:1855619, PMID:2086312, PMID:2537085, PMID:3247000, PMID:3945941, PMID:4859365, PMID:6933967, PMID:7150809, PMID:7218377, PMID:7234437, PMID:7713347, PMID:8231460, PMID:8359835, PMID:8579882, PMID:8783813, PMID:9268605, PMID:9515941, PMID:9586870, PMID:10421444, PMID:10975133, PMID:12018594, PMID:14631503, PMID:15033007, PMID:15679473, PMID:15793557, PMID:15979224, PMID:16036766, PMID:16193528, PMID:16598855, PMID:16978018, PMID:17188317, PMID:17722737, PMID:18070496, PMID:18423506, PMID:19100812, PMID:19631781, PMID:20026515, PMID:20396698, PMID:20412842, PMID:21251949, PMID:21349312, PMID:21673941, PMID:21767560, PMID:22209767, PMID:22783142, PMID:23220589, PMID:25082528, PMID:25895260, PMID:26814074, PMID:27899289, PMID:30625376 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization
multiple interactions
EXP Dichlorvos affects the localization of AIFM1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos affects the localization of AIFM1 protein]
CTD PMID:24231740 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Dichlorvos results in increased expression of AKR7A3 mRNA CTD PMID:21813463 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Alb albumin affects binding ISO Dichlorvos binds to ALB protein CTD PMID:15525694, PMID:17188226 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Dichlorvos results in increased expression of ALDH1A1 mRNA CTD PMID:21813463 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Anxa2 annexin A2 increases expression EXP Dichlorvos results in increased expression of ANXA2 mRNA CTD PMID:21813463 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Apeh acylaminoacyl-peptide hydrolase decreases activity ISO
EXP
Dichlorvos results in decreased activity of APEH protein CTD PMID:15888665, PMID:19379766 NCBI chr 8:116,862,664...116,871,776
Ensembl chr 8:116,862,625...116,872,215
JBrowse link
G App amyloid beta precursor protein increases secretion ISO
EXP
Dichlorvos results in increased secretion of APP protein alternative form
Dichlorvos results in increased secretion of APP protein modified form
CTD PMID:7605915, PMID:8624119, PMID:11526466 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor multiple interactions ISO Dichlorvos promotes the reaction [Metribolone results in increased activity of AR protein] CTD PMID:17219378 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ATM mRNA]
Dichlorvos results in increased expression of ATM mRNA; Dichlorvos results in increased expression of ATM protein
CTD PMID:24369695 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Dichlorvos results in increased expression of BAX protein CTD PMID:22817663 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases expression
decreases activity
ISO
EXP
[Dichlorvos results in decreased activity of BCHE protein] which results in increased susceptibility to Succinylcholine; Dichlorvos binds to and results in decreased activity of BCHE protein; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]
Dichlorvos results in decreased expression of BCHE protein
diacetylmonoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Magnesium Sulfate promotes the reaction [Dichlorvos results in decreased activity of BCHE protein]
[bacoside A co-treated with Plant Preparations] inhibits the reaction [Dichlorvos results in decreased expression of BCHE protein]; Dichlorvos binds to and results in decreased activity of BCHE protein
CTD PMID:235931, PMID:423703, PMID:1276991, PMID:4631366, PMID:7150809, PMID:12190811, PMID:12828128, PMID:16036766, PMID:16193528, PMID:16598855, PMID:17698511, PMID:19504058, PMID:20229498, PMID:20395308, PMID:21673941, PMID:21767560, PMID:22209767, PMID:27899289 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Dichlorvos results in increased expression of BTG2 mRNA CTD PMID:21813463 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Casp1 caspase 1 increases expression EXP Dichlorvos results in increased expression of CASP1 mRNA CTD PMID:23053939 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
increases expression
decreases expression
multiple interactions
ISO
EXP
Dichlorvos results in increased activity of CASP3 protein
Dichlorvos results in increased cleavage of CASP3 protein
Dichlorvos results in increased expression of CASP3 mRNA
Dichlorvos results in decreased expression of CASP3 mRNA
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; Dichlorvos results in increased cleavage of and results in increased activity of CASP3 protein; TEMPOL-H inhibits the reaction [Dichlorvos results in increased cleavage of CASP3 protein]
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]
CTD PMID:16973328, PMID:17681413, PMID:17850875, PMID:19815060, PMID:21784090, PMID:22817663, PMID:24369695 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
EXP [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein] CTD PMID:16973328 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
increases activity
decreases activity
EXP
ISO
[Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of CAT protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of CAT protein; [Phorate co-treated with acephate co-treated with Dichlorvos co-treated with Dimethoate] results in decreased activity of CAT protein; Acetylcysteine inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; coenzyme Q10 inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]
Dichlorvos results in increased activity of CAT protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]
CTD PMID:1587340, PMID:20302853, PMID:22034174, PMID:22224058, PMID:22751200, PMID:25891459, PMID:26814074, PMID:27180203, PMID:29143438 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cdc25a cell division cycle 25A increases expression
multiple interactions
EXP Dichlorvos results in increased expression of CDC25A mRNA; Dichlorvos results in increased expression of CDC25A protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDC25A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDC25A protein]
CTD PMID:24369695 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
EXP Dichlorvos results in increased expression of CDKN1A mRNA; Dichlorvos results in increased expression of CDKN1A protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A protein]
CTD PMID:21813463, PMID:24369695 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Dichlorvos results in increased expression of CES2 mRNA CTD PMID:21813463 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Chat choline O-acetyltransferase increases activity EXP Dichlorvos results in increased activity of CHAT protein CTD PMID:17722737 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 protein]
Dichlorvos results in increased expression of CHEK2 mRNA; Dichlorvos results in increased expression of CHEK2 protein
CTD PMID:24369695 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP Dichlorvos results in decreased expression of CHRM1 protein CTD PMID:19100812 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases expression EXP Dichlorvos results in decreased expression of CHRM2 protein CTD PMID:19100812 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 decreases expression EXP Dichlorvos results in decreased expression of CHRM3 protein CTD PMID:19100812 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Dichlorvos inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:15733544 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Dichlorvos inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:15733544 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases activity
ISO Dichlorvos inhibits the reaction [CP 55244 binds to CNR1 protein]
Dichlorvos results in decreased activity of CNR1 protein
CTD PMID:12243867 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation EXP Dichlorvos results in decreased phosphorylation of CREB1 protein CTD PMID:19100812 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression EXP Dichlorvos results in increased expression of CYBB mRNA; Dichlorvos results in increased expression of CYBB protein CTD PMID:21964614 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
EXP Dichlorvos affects the localization of CYCS protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [Dichlorvos affects the localization of CYCS protein]
CTD PMID:17850875, PMID:21784090 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Dbh dopamine beta-hydroxylase increases activity
multiple interactions
EXP Dichlorvos results in increased activity of DBH protein
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of DBH protein]
CTD PMID:12186780 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 affects response to substance ISO DLG2 gene SNP affects the susceptibility to Dichlorvos CTD PMID:25622337 NCBI chr 1:154,916,274...157,274,077
Ensembl chr 1:156,552,328...157,269,747
JBrowse link
G Drd2 dopamine receptor D2 decreases activity
multiple interactions
EXP Dichlorvos results in decreased activity of DRD2 protein
Nimodipine inhibits the reaction [Dichlorvos results in decreased activity of DRD2 protein]
CTD PMID:12186780 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Esr1 estrogen receptor 1 decreases activity ISO Dichlorvos results in decreased activity of ESR1 protein CTD PMID:22562034 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Dichlorvos results in decreased expression of FAS protein CTD PMID:15369847 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand decreases expression ISO Dichlorvos results in decreased expression of FASL protein CTD PMID:15369847 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta decreases expression EXP Dichlorvos results in decreased expression of GABRD mRNA CTD PMID:19146868 NCBI chr 5:172,797,478...172,809,374
Ensembl chr 5:172,797,450...172,809,353
JBrowse link
G Gck glucokinase decreases activity
increases expression
EXP Dichlorvos results in decreased activity of GCK protein
Dichlorvos results in increased expression of GCK mRNA
CTD PMID:16153661 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
increases activity
decreases activity
multiple interactions
EXP Dichlorvos results in decreased expression of GSR protein
Dichlorvos results in increased activity of GSR protein
Dichlorvos results in decreased activity of GSR protein
[Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of GSR protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of GSR protein; Dichlorvos inhibits the reaction [sodium arsenite results in increased activity of GSR protein]; Plant Extracts inhibits the reaction [Dichlorvos results in decreased activity of GSR protein]; sodium arsenite inhibits the reaction [Dichlorvos results in increased activity of GSR protein]
CTD PMID:18539328, PMID:20302853, PMID:22224058, PMID:22751200, PMID:25895260 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gys2 glycogen synthase 2 increases activity EXP Dichlorvos results in increased activity of GYS2 protein CTD PMID:222008 NCBI chr 4:176,638,632...176,679,805
Ensembl chr 4:176,638,629...176,679,815
JBrowse link
G Gzma granzyme A decreases expression ISO Dichlorvos results in decreased expression of GZMA mRNA; Dichlorvos results in decreased expression of GZMA protein CTD PMID:16002202 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Gzmb granzyme B decreases expression ISO Dichlorvos results in decreased expression of GZMB protein CTD PMID:18063463 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Gzmk granzyme K decreases expression ISO Dichlorvos results in decreased expression of GZMK protein CTD PMID:18063463 NCBI chr 2:45,069,136...45,077,154
Ensembl chr 2:45,068,967...45,077,219
JBrowse link
G Hdc histidine decarboxylase increases activity EXP Dichlorvos results in increased activity of HDC protein CTD PMID:119426 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hk1 hexokinase 1 decreases activity EXP Dichlorvos results in decreased activity of HK1 protein CTD PMID:10544956 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO Dichlorvos results in decreased expression of HMOX1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of HMOX1 protein]
CTD PMID:26814074 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifng interferon gamma decreases expression EXP Dichlorvos results in decreased expression of IFNG protein CTD PMID:19145326 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion
EXP Dichlorvos results in increased expression of IL1B mRNA; Dichlorvos results in increased expression of IL1B protein
Dichlorvos results in increased secretion of IL1B protein
CTD PMID:21964614, PMID:22817663 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 decreases response to substance ISO Dichlorvos results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6 interleukin 6 increases expression EXP Dichlorvos results in increased expression of IL6 mRNA; Dichlorvos results in increased expression of IL6 protein CTD PMID:21964614 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
EXP Dichlorvos results in increased expression of ITGAM mRNA; Dichlorvos results in increased expression of ITGAM protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ITGAM protein]
CTD PMID:21964614, PMID:22817663, PMID:24369695 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Lcat lecithin cholesterol acyltransferase decreases activity
multiple interactions
ISO Dichlorvos results in decreased activity of LCAT protein
Dichlorvos inhibits the reaction [[LCAT protein results in increased metabolism of Lecithins] which results in increased chemical synthesis of Cholesterol Esters]
CTD PMID:4847537 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lpl lipoprotein lipase decreases activity EXP Dichlorvos results in decreased activity of LPL protein CTD PMID:3196159 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Maoa monoamine oxidase A decreases activity EXP Dichlorvos results in decreased activity of MAOA protein CTD PMID:12018584 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Maob monoamine oxidase B decreases activity EXP Dichlorvos results in decreased activity of MAOB protein CTD PMID:12018584 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
increases phosphorylation
EXP Nimodipine inhibits the reaction [Dichlorvos results in increased phosphorylation of MAP2 protein] CTD PMID:11282359, PMID:16635102 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP Dichlorvos results in increased expression of MGMT mRNA CTD PMID:21813463 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 affects expression
decreases activity
EXP
ISO
Dichlorvos affects the expression of NCEH1 protein modified form
Dichlorvos results in decreased activity of NCEH1 protein
CTD PMID:6245657, PMID:16978018 NCBI chr 2:112,868,834...112,932,622
Ensembl chr 2:112,868,707...112,934,953
JBrowse link
G Nefh neurofilament heavy affects expression EXP Dichlorvos affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light decreases expression EXP Dichlorvos results in decreased expression of NEFL mRNA CTD PMID:19146868 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
decreases expression
multiple interactions
ISO Dichlorvos results in increased activity of NFE2L2 protein
Dichlorvos results in decreased expression of NFE2L2 mRNA; Dichlorvos results in decreased expression of NFE2L2 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 protein]
CTD PMID:20143881, PMID:25891459, PMID:26814074 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
EXP Dichlorvos results in increased expression of NOS2 mRNA; Dichlorvos results in increased expression of NOS2 protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of NOS2 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of NOS2 protein]
CTD PMID:22817663, PMID:24369695 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO Dichlorvos results in decreased expression of NQO1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NQO1 protein]
CTD PMID:26814074 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases activity
increases cleavage
multiple interactions
EXP Dichlorvos results in increased activity of PARP1 protein
Dichlorvos results in increased cleavage of PARP1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in increased activity of PARP1 protein]
CTD PMID:24231740 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases activity ISO
EXP
Dichlorvos results in decreased activity of PNPLA6 protein CTD PMID:7713347, PMID:9268605, PMID:9586870, PMID:10776595, PMID:11282359, PMID:11705460 NCBI chr12:2,068,749...2,098,139
Ensembl chr12:2,069,959...2,097,904
JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases secretion
EXP Dichlorvos inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones]
Dichlorvos results in increased secretion of POMC protein modified form
CTD PMID:2993719, PMID:6245657 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
decreases expression
decreases response to substance
EXP
ISO
1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)but-2-ene inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; asoxime chloride inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]
Dichlorvos results in decreased expression of PON1 mRNA; Dichlorvos results in decreased expression of PON1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of HMOX1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NQO1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of PON1 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of PON1 protein]
PON1 protein results in decreased susceptibility to Dichlorvos
CTD PMID:20412842, PMID:25891459, PMID:26814074, PMID:29098328 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Prf1 perforin 1 decreases expression ISO Dichlorvos results in decreased expression of PRF1 mRNA; Dichlorvos results in decreased expression of PRF1 protein CTD PMID:16002202 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of PRKDC mRNA]
Dichlorvos results in increased expression of PRKDC mRNA; Dichlorvos results in increased expression of PRKDC protein
CTD PMID:24369695 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Pygb glycogen phosphorylase B increases activity EXP Dichlorvos results in increased activity of PYGB protein CTD PMID:10544956 NCBI chr 3:146,581,063...146,629,504
Ensembl chr 3:146,582,752...146,634,535
JBrowse link
G Pygl glycogen phosphorylase L increases activity EXP Dichlorvos results in increased activity of PYGL protein CTD PMID:222008 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Snca synuclein alpha multiple interactions
affects localization
EXP coenzyme Q10 inhibits the reaction [Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]]; Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]
Dichlorvos affects the localization of SNCA protein
CTD PMID:21073741, PMID:21843543 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases activity
EXP [10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide results in increased expression of SOD2 protein] which results in decreased susceptibility to Dichlorvos; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of SOD2 protein] CTD PMID:17850875, PMID:21784090, PMID:24231740 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression EXP Dichlorvos results in increased expression of TAP1 mRNA CTD PMID:21813463 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tat tyrosine aminotransferase multiple interactions
increases expression
EXP [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tf transferrin affects binding ISO Dichlorvos binds to TF protein
Dichlorvos binds to TRF protein
CTD PMID:18930948 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Th tyrosine hydroxylase increases activity
multiple interactions
EXP Dichlorvos results in increased activity of TH protein
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein]
CTD PMID:12186780 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tnf tumor necrosis factor increases expression
increases secretion
EXP Dichlorvos results in increased expression of TNF mRNA; Dichlorvos results in increased expression of TNF protein
Dichlorvos results in increased secretion of TNF protein
CTD PMID:21964614, PMID:22817663, PMID:23053939 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 decreases expression
increases expression
multiple interactions
EXP Dichlorvos results in decreased expression of TP53 mRNA
Dichlorvos results in increased expression of TP53 mRNA; Dichlorvos results in increased expression of TP53 protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 protein]
CTD PMID:23053939, PMID:24369695 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tubb5 tubulin, beta 5 class I increases phosphorylation EXP Dichlorvos results in increased phosphorylation of TUBB protein CTD PMID:11282359, PMID:16635102 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 decreases activity EXP Dichlorvos results in decreased activity of UGP2 protein CTD PMID:222008 NCBI chr14:106,208,174...106,249,322
Ensembl chr14:106,208,176...106,248,539
JBrowse link
G Xab2 XPA binding protein 2 affects response to substance ISO XAB2 gene SNP affects the susceptibility to Dichlorvos CTD PMID:22102698 NCBI chr12:2,158,391...2,170,397
Ensembl chr12:2,158,389...2,170,504
JBrowse link
dicofol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor affects binding
multiple interactions
ISO Dicofol binds to AR protein
Dicofol inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Dicofol inhibits the reaction [Metribolone results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [Dicofol results in increased activity of AR protein]
CTD PMID:15064155, PMID:15253041, PMID:18324785, PMID:21310686 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Dicofol results in decreased activity of CYP19A1 protein CTD PMID:10806373 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP1A1 mRNA; Dicofol results in increased expression of CYP1A1 protein CTD PMID:19595748 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP Dicofol results in increased expression of CYP1A2 mRNA CTD PMID:19595748 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP2B1 protein CTD PMID:19595748 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Dicofol results in increased expression of CYP2B2 protein CTD PMID:19595748 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP2E1 protein CTD PMID:19595748 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Dicofol results in increased expression of CYP3A23-3A1 mRNA CTD PMID:19595748 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Dicofol results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
increases activity
ISO Dicofol binds to ESR1 protein
Dicofol binds to and results in increased activity of ESR1 protein
Dicofol results in increased activity of ESR1 protein
CTD PMID:10789375, PMID:15064155, PMID:15253041, PMID:16337670, PMID:29162470 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO Dicofol results in increased activity of ESR2 protein CTD PMID:15064155 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases activity EXP Dicofol results in increased activity of GGT1 protein CTD PMID:2387028 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP Dicofol results in increased activity of GPT protein CTD PMID:2387028 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Dicofol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Dicofol inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Dicofol binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Dicofol results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Prkcb protein kinase C, beta multiple interactions
increases activity
ISO Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein]; Phosphatidylserines promotes the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Ttr transthyretin affects binding EXP Dicofol binds to TTR protein CTD PMID:2043046 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
fluvalinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO fluvalinate analog promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:25684042 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Cdk2 cyclin dependent kinase 2 affects binding ISO fluvalinate binds to CDK2 protein CTD PMID:32278787 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects binding ISO fluvalinate binds to ERBB2 protein CTD PMID:32278787 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects binding ISO fluvalinate binds to FGFR2 protein CTD PMID:32278787 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Mmp9 matrix metallopeptidase 9 affects binding ISO fluvalinate binds to MMP9 protein CTD PMID:32278787 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 affects binding ISO fluvalinate binds to NQO1 protein CTD PMID:32278787 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO fluvalinate inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO fluvalinate binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO fluvalinate binds to PPARD protein CTD PMID:32278787 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Rora RAR-related orphan receptor A affects binding ISO fluvalinate binds to RORA protein CTD PMID:32278787 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rorc RAR-related orphan receptor C affects binding ISO fluvalinate binds to RORC protein CTD PMID:32278787 NCBI chr 2:195,612,471...195,636,797
Ensembl chr 2:195,617,021...195,637,630
JBrowse link
pyridaben term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco2 aconitase 2 decreases activity EXP pyridaben results in decreased activity of ACO2 protein CTD PMID:26141520 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 increases expression ISO pyridaben results in increased expression of ADAM22 mRNA CTD PMID:22563483 NCBI chr 4:22,864,485...23,002,969
Ensembl chr 4:22,859,622...22,996,645
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases expression ISO pyridaben results in increased expression of ADCYAP1 mRNA CTD PMID:22563483 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Ago3 argonaute RISC catalytic component 3 increases expression ISO pyridaben results in increased expression of AGO3 mRNA CTD PMID:22563483 NCBI chr 5:144,355,792...144,436,509
Ensembl chr 5:144,364,269...144,436,509
JBrowse link
G Amn amnion associated transmembrane protein decreases expression ISO pyridaben results in decreased expression of AMN mRNA CTD PMID:22563483 NCBI chr 6:135,724,455...135,731,896
Ensembl chr 6:135,724,455...135,731,896
JBrowse link
G Ar androgen receptor multiple interactions ISO pyridaben inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:30818834 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atoh7 atonal bHLH transcription factor 7 decreases expression ISO pyridaben results in decreased expression of ATOH7 mRNA CTD PMID:22563483 NCBI chr20:27,082,961...27,083,410
Ensembl chr20:27,082,961...27,083,410
JBrowse link
G Atp8a2 ATPase phospholipid transporting 8A2 increases expression ISO pyridaben results in increased expression of ATP8A2 mRNA CTD PMID:22563483 NCBI chr15:39,955,689...40,488,737
Ensembl chr15:40,000,322...40,428,800
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
multiple interactions
ISO BCL2 protein results in decreased susceptibility to pyridaben
PK 11195 inhibits the reaction [BCL2 protein results in decreased susceptibility to pyridaben]
CTD PMID:12730627 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO pyridaben results in increased expression of BCL2A1 mRNA CTD PMID:22563483 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bicd1 BICD cargo adaptor 1 increases expression ISO pyridaben results in increased expression of BICD1 mRNA CTD PMID:22563483 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540
JBrowse link
G C2cd4d C2 calcium-dependent domain containing 4D decreases expression ISO pyridaben results in decreased expression of C2CD4D mRNA CTD PMID:22563483 NCBI chr 2:195,599,706...195,604,730
Ensembl chr 2:195,603,599...195,604,624
JBrowse link
G Cabyr calcium binding tyrosine phosphorylation regulated increases expression ISO pyridaben results in increased expression of CABYR mRNA CTD PMID:22563483 NCBI chr18:4,082,175...4,096,650
Ensembl chr18:4,084,228...4,095,936
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases expression ISO pyridaben results in increased expression of CACNA1E mRNA CTD PMID:22563483 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression ISO pyridaben results in increased expression of CAMP mRNA CTD PMID:22563483 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518
JBrowse link
G Capn11 calpain 11 decreases expression ISO pyridaben results in decreased expression of CAPN11 mRNA CTD PMID:22563483 NCBI chr 9:17,728,845...17,750,357
Ensembl chr 9:17,728,816...17,750,363
JBrowse link
G Ccdc88a coiled coil domain containing 88A increases expression ISO pyridaben results in increased expression of CCDC88A mRNA CTD PMID:22563483 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO pyridaben results in increased expression of CCL19 mRNA CTD PMID:22563483 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 increases expression ISO pyridaben results in increased expression of CCL21A mRNA CTD PMID:22563483 NCBI chr 5:58,197,678...58,198,782
Ensembl chr 5:58,197,680...58,198,782
JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression ISO pyridaben results in decreased expression of CDHR4 mRNA CTD PMID:22563483 NCBI chr 8:116,771,377...116,779,242 JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression ISO pyridaben results in decreased expression of CEBPD mRNA CTD PMID:22563483 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cep290 centrosomal protein 290 increases expression ISO pyridaben results in increased expression of CEP290 mRNA CTD PMID:22563483 NCBI chr 7:40,217,269...40,306,327
Ensembl chr 7:40,217,269...40,306,327
JBrowse link
G Cldn3 claudin 3 decreases expression ISO pyridaben results in decreased expression of CLDN3 mRNA CTD PMID:22563483 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Crlf2 cytokine receptor-like factor 2 decreases expression ISO pyridaben results in decreased expression of CRLF2 mRNA CTD PMID:22563483 NCBI chr14:1,456,843...1,461,543
Ensembl chr14:1,456,844...1,461,543
JBrowse link
G Dgki diacylglycerol kinase, iota increases expression ISO pyridaben results in increased expression of DGKI mRNA CTD PMID:22563483 NCBI chr 4:64,365,115...64,831,473
Ensembl chr 4:64,374,342...64,831,473
JBrowse link
G Dip2b disco-interacting protein 2 homolog B increases expression ISO pyridaben results in increased expression of DIP2B mRNA CTD PMID:22563483 NCBI chr 7:141,702,034...141,878,945
Ensembl chr 7:141,702,038...141,879,951
JBrowse link
G Dmrta2 DMRT-like family A2 decreases expression ISO pyridaben results in decreased expression of DMRTA2 mRNA CTD PMID:22563483 NCBI chr 5:129,754,295...129,760,045
Ensembl chr 5:129,756,149...129,758,986
JBrowse link
G Drd4 dopamine receptor D4 decreases expression ISO pyridaben results in decreased expression of DRD4 mRNA CTD PMID:22563483 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Egr4 early growth response 4 decreases expression ISO pyridaben results in decreased expression of EGR4 mRNA CTD PMID:22563483 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
JBrowse link
G Elane elastase, neutrophil expressed increases expression ISO pyridaben results in increased expression of ELANE mRNA CTD PMID:22563483 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Esr1 estrogen receptor 1 increases activity
multiple interactions
ISO pyridaben results in increased activity of ESR1 protein
pyridaben inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
CTD PMID:20143881, PMID:30818834 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO pyridaben inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:30818834 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO pyridaben inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]; pyridaben inhibits the reaction [XCT790 results in decreased activity of ESRRA protein] CTD PMID:30818834 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Etl4 enhancer trap locus 4 increases expression ISO pyridaben results in increased expression of ETL4 mRNA CTD PMID:22563483 NCBI chr17:87,173,265...87,681,268
Ensembl chr17:87,274,944...87,681,317
JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO pyridaben results in decreased expression of H2BC9 mRNA CTD PMID:22563483 NCBI chr17:44,519,815...44,520,269
Ensembl chr17:44,519,860...44,520,240
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions EXP zinc chloride inhibits the reaction [pyridaben results in increased secretion of HEXB protein] CTD PMID:15272608 NCBI chr 2:27,983,925...28,003,260
Ensembl chr 2:27,984,117...28,003,186
JBrowse link
G Hist2h3c2 histone cluster 2 H3 family member C2 decreases expression ISO pyridaben results in decreased expression of H3C1 mRNA CTD PMID:22563483 NCBI chr 2:198,390,024...198,418,075
Ensembl chr 2:198,417,619...198,418,029
JBrowse link
G Hmx3 H6 family homeobox 3 decreases expression ISO pyridaben results in decreased expression of HMX3 mRNA CTD PMID:22563483 NCBI chr 1:203,509,731...203,511,695
Ensembl chr 1:203,509,731...203,511,695
JBrowse link
G Hs3st6 heparan sulfate-glucosamine 3-sulfotransferase 6 decreases expression ISO pyridaben results in decreased expression of HS3ST6 mRNA CTD PMID:22563483 NCBI chr10:14,122,856...14,128,984
Ensembl chr10:14,122,878...14,128,983
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO pyridaben results in decreased expression of IDH3A mRNA CTD PMID:30818834 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Inhba inhibin subunit beta A increases expression ISO pyridaben results in increased expression of INHBA mRNA CTD PMID:22563483 NCBI chr17:51,894,869...51,919,998
Ensembl chr17:51,898,217...51,912,496
JBrowse link
G Insl3 insulin-like 3 decreases expression ISO pyridaben results in decreased expression of INSL3 mRNA CTD PMID:22563483 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Itgb8 integrin subunit beta 8 increases expression ISO pyridaben results in increased expression of ITGB8 mRNA CTD PMID:22563483 NCBI chr 6:147,089,280...147,172,846
Ensembl chr 6:147,094,097...147,172,813
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 increases expression ISO pyridaben results in increased expression of KCNA2 mRNA CTD PMID:22563483 NCBI chr 2:209,838,607...209,852,471
Ensembl chr 2:209,838,869...209,852,471
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 increases expression ISO pyridaben results in increased expression of KCNMA1 mRNA CTD PMID:22563483 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Kif1b kinesin family member 1B increases expression ISO pyridaben results in increased expression of KIF1B mRNA CTD PMID:22563483 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Klf2 Kruppel-like factor 2 decreases expression ISO pyridaben results in decreased expression of KLF2 mRNA CTD PMID:22563483 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037
JBrowse link
G Klhl15 kelch-like family member 15 increases expression ISO pyridaben results in increased expression of KLHL15 mRNA CTD PMID:22563483 NCBI chr  X:63,342,277...63,390,915
Ensembl chr  X:63,343,546...63,389,989
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO pyridaben results in increased expression of LAMC2 mRNA CTD PMID:22563483 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Lifr LIF receptor subunit alpha increases expression ISO pyridaben results in increased expression of LIFR mRNA CTD PMID:22563483 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link
G LOC102548682 histone H4-like decreases expression ISO pyridaben results in decreased expression of H4C14 mRNA CTD PMID:22563483 NCBI chr17:43,616,218...43,673,659
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr17:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
Ensembl chr 2:43,791,657...43,792,067
JBrowse link
G Lrp4 LDL receptor related protein 4 increases expression ISO pyridaben results in increased expression of LRP4 mRNA CTD PMID:22563483 NCBI chr 3:80,362,643...80,416,684
Ensembl chr 3:80,362,858...80,416,679
JBrowse link
G Lrrc63 leucine rich repeat containing 63 decreases expression ISO pyridaben results in decreased expression of LRRC63 mRNA CTD PMID:22563483 NCBI chr15:57,132,507...57,170,467
Ensembl chr15:57,133,192...57,170,443
JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 decreases expression ISO pyridaben results in decreased expression of LTB4R2 mRNA CTD PMID:22563483 NCBI chr15:34,446,478...34,448,220
Ensembl chr15:34,446,878...34,447,954
JBrowse link
G Ltf lactotransferrin increases expression ISO pyridaben results in increased expression of LTF mRNA CTD PMID:22563483 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Mapk15 mitogen-activated protein kinase 15 decreases expression ISO pyridaben results in decreased expression of MAPK15 mRNA CTD PMID:22563483 NCBI chr 7:117,041,287...117,061,799
Ensembl chr 7:117,055,395...117,061,047
JBrowse link
G Marchf9 membrane associated ring-CH-type finger 9 decreases expression ISO pyridaben results in decreased expression of MARCHF9 mRNA CTD PMID:22563483 NCBI chr 7:70,341,989...70,349,126 JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 increases expression ISO pyridaben results in increased expression of MBOAT2 mRNA CTD PMID:22563483 NCBI chr 6:44,009,872...44,135,501
Ensembl chr 6:44,009,872...44,131,387
JBrowse link
G Mdfi MyoD family inhibitor decreases expression ISO pyridaben results in decreased expression of MDFI mRNA CTD PMID:22563483 NCBI chr 9:15,166,118...15,184,469
Ensembl chr 9:15,166,118...15,184,468
JBrowse link
G Mpo myeloperoxidase increases expression ISO pyridaben results in increased expression of MPO mRNA CTD PMID:22563483 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrtfb myocardin related transcription factor B increases expression ISO pyridaben results in increased expression of MRTFB mRNA CTD PMID:22563483 NCBI chr10:1,151,163...1,273,269 JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming increases expression ISO pyridaben results in increased expression of MUC6 mRNA CTD PMID:22563483 NCBI chr 1:214,608,453...214,630,524
Ensembl chr 1:214,608,704...214,629,938
JBrowse link
G Myoc myocilin increases expression ISO pyridaben results in increased expression of MYOC mRNA CTD PMID:22563483 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928
JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO pyridaben results in increased expression of NFAT5 mRNA CTD PMID:22563483 NCBI chr19:38,446,059...38,533,735
Ensembl chr19:38,446,059...38,533,735
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity ISO pyridaben results in increased activity of NFE2L2 protein CTD PMID:30818834 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfib nuclear factor I/B increases expression ISO pyridaben results in increased expression of NFIB mRNA CTD PMID:22563483 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nipbl NIPBL, cohesin loading factor increases expression ISO pyridaben results in increased expression of NIPBL mRNA CTD PMID:22563483 NCBI chr 2:57,508,830...57,676,197
Ensembl chr 2:57,509,428...57,600,820
JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 decreases response to substance ISO NMNAT3 protein results in decreased susceptibility to pyridaben CTD PMID:18463239 NCBI chr 8:106,317,038...106,429,535
Ensembl chr 8:106,317,124...106,429,522
JBrowse link
G Nps neuropeptide S increases expression ISO pyridaben results in increased expression of NPS mRNA CTD PMID:22563483 NCBI chr 1:207,508,414...207,512,195
Ensembl chr 1:207,508,414...207,512,195
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression ISO pyridaben results in decreased expression of NR4A1 mRNA CTD PMID:22563483 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases activity
ISO pyridaben inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]
pyridaben results in increased activity of ODC1 protein
CTD PMID:9834970 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide decreases expression ISO pyridaben results in decreased expression of OXT mRNA CTD PMID:22563483 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Park7 Parkinsonism associated deglycase decreases response to substance ISO PARK7 protein results in decreased susceptibility to pyridaben CTD PMID:21219333 NCBI chr 5:167,982,438...168,004,724
Ensembl chr 5:167,982,439...168,004,724
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO pyridaben results in increased cleavage of PARP1 protein
[pyridaben co-treated with Paraquat] results in increased cleavage of PARP1 protein
CTD PMID:16237197 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pgr progesterone receptor multiple interactions ISO pyridaben inhibits the reaction [Promegestone results in increased activity of PGR protein] CTD PMID:30818834 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Phox2a paired-like homeobox 2a decreases expression ISO pyridaben results in decreased expression of PHOX2A mRNA CTD PMID:22563483 NCBI chr 1:166,893,734...166,898,252
Ensembl chr 1:166,893,734...166,898,252
JBrowse link
G Plce1 phospholipase C, epsilon 1 increases expression ISO pyridaben results in increased expression of PLCE1 mRNA CTD PMID:22563483 NCBI chr 1:257,156,023...257,465,440
Ensembl chr 1:257,157,264...257,466,064
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO pyridaben inhibits the reaction [Rosiglitazone results in increased activity of PPARG protein] CTD PMID:30818834 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression
multiple interactions
ISO pyridaben results in increased expression of PPARGC1A mRNA
pyridaben inhibits the reaction [PPARGC1A protein results in increased activity of ESRRA protein]
CTD PMID:22563483, PMID:30818834 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prr7 proline rich 7 (synaptic) decreases expression ISO pyridaben results in decreased expression of PRR7 mRNA CTD PMID:22563483 NCBI chr17:9,693,274...9,702,795
Ensembl chr17:9,694,168...9,695,292
JBrowse link
G Retnlb resistin like beta increases expression ISO pyridaben results in increased expression of RETNLB mRNA CTD PMID:22563483 NCBI chr11:54,565,471...54,567,578
Ensembl chr11:54,565,472...54,567,357
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 increases expression ISO pyridaben results in increased expression of ROCK1 mRNA CTD PMID:22563483 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO pyridaben results in increased expression of S100A8 mRNA CTD PMID:22563483 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO pyridaben results in increased expression of S100A9 mRNA CTD PMID:22563483 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Shox2 short stature homeobox 2 decreases expression ISO pyridaben results in decreased expression of SHOX2 mRNA CTD PMID:22563483 NCBI chr 2:164,118,175...164,126,783
Ensembl chr 2:164,118,191...164,126,783
JBrowse link
G Slc8a1 solute carrier family 8 member A1 increases expression ISO pyridaben results in increased expression of SLC8A1 mRNA CTD PMID:22563483 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Smoc2 SPARC related modular calcium binding 2 increases expression ISO pyridaben results in increased expression of SMOC2 mRNA CTD PMID:22563483 NCBI chr 1:56,242,289...56,374,106
Ensembl chr 1:56,242,346...56,374,120
JBrowse link
G Snca synuclein alpha increases response to substance ISO SNCA protein results in increased susceptibility to pyridaben CTD PMID:16239214 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO pyridaben results in decreased expression of SOCS1 mRNA CTD PMID:22563483 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Ston2 stonin 2 increases expression ISO pyridaben results in increased expression of STON2 mRNA CTD PMID:22563483 NCBI chr 6:115,398,586...115,547,552
Ensembl chr 6:115,399,326...115,513,354
JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression ISO pyridaben results in increased expression of STRBP mRNA CTD PMID:22563483 NCBI chr 3:21,817,680...21,956,988
Ensembl chr 3:21,828,298...21,904,270
JBrowse link
G Tbck TBC1 domain containing kinase increases expression ISO pyridaben results in increased expression of TBCK mRNA CTD PMID:22563483 NCBI chr 2:237,751,646...237,958,497
Ensembl chr 2:237,751,654...237,958,497
JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO pyridaben results in decreased expression of TCF15 mRNA CTD PMID:22563483 NCBI chr 3:147,643,250...147,649,511
Ensembl chr 3:147,643,250...147,649,504
JBrowse link
G Tmem42 transmembrane protein 42 decreases expression ISO pyridaben results in decreased expression of TMEM42 mRNA CTD PMID:22563483 NCBI chr 8:132,105,965...132,108,462
Ensembl chr 8:132,105,443...132,108,462
JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression ISO pyridaben results in increased expression of TNNT2 mRNA CTD PMID:22563483 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 increases expression ISO pyridaben results in increased expression of TRPM3 mRNA CTD PMID:22563483 NCBI chr 1:239,741,572...240,757,583
Ensembl chr 1:240,355,149...240,757,583
JBrowse link
G Ubxn7 UBX domain protein 7 increases expression ISO pyridaben results in increased expression of UBXN7 mRNA CTD PMID:22563483 NCBI chr11:71,662,786...71,695,031 JBrowse link
G Ucn urocortin decreases expression ISO pyridaben results in decreased expression of UCN mRNA CTD PMID:22563483 NCBI chr 6:26,602,144...26,602,974
Ensembl chr 6:26,602,144...26,602,974
JBrowse link
G Unc13c unc-13 homolog C increases expression ISO pyridaben results in increased expression of UNC13C mRNA CTD PMID:22563483 NCBI chr 8:80,202,736...80,656,363
Ensembl chr 8:80,203,609...80,631,926
JBrowse link
G Vdr vitamin D receptor increases activity ISO pyridaben results in increased activity of VDR protein CTD PMID:20143881 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Zbtb44 zinc finger and BTB domain containing 44 increases expression ISO pyridaben results in increased expression of ZBTB44 mRNA CTD PMID:22563483 NCBI chr 8:32,165,388...32,223,341
Ensembl chr 8:32,165,810...32,217,476
JBrowse link
G Zfp580 zinc finger protein 580 decreases expression ISO pyridaben results in decreased expression of ZFP580 mRNA CTD PMID:22563483 NCBI chr 1:72,338,468...72,340,636
Ensembl chr 1:72,338,877...72,339,395
JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 increases expression ISO pyridaben results in increased expression of ZHX3 mRNA CTD PMID:22563483 NCBI chr 3:156,759,820...156,868,173
Ensembl chr 3:156,764,751...156,777,999
JBrowse link
tetradifon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 increases activity ISO tetradifon results in increased activity of ESR1 protein CTD PMID:26139245 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 increases activity ISO tetradifon results in increased activity of ESR2 protein CTD PMID:26139245 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        pesticide 16264
          organochlorine pesticide 6113
            organochlorine acaricide 209
              azamethiphos 5
              benzoximate 0
              chlorfenapyr 0
              chlorfenvinfos 2
              chloropropylate 4
              clofentezine 0
              dichlorvos 83
              dicofol 19
              fluazuron 0
              flumethrin 0
              fluvalinate + 11
              hexythiazox + 0
              pyridaben 102
              spirodiclofen 0
              tetradifon 2
              tralopyril + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            heteroorganic entity 19148
                              organohalogen compound 17712
                                organochlorine compound 17466
                                  organochlorine pesticide 6113
                                    organochlorine acaricide 209
                                      azamethiphos 5
                                      benzoximate 0
                                      chlorfenapyr 0
                                      chlorfenvinfos 2
                                      chloropropylate 4
                                      clofentezine 0
                                      dichlorvos 83
                                      dicofol 19
                                      fluazuron 0
                                      flumethrin 0
                                      fluvalinate + 11
                                      hexythiazox + 0
                                      pyridaben 102
                                      spirodiclofen 0
                                      tetradifon 2
                                      tralopyril + 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.