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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tyrosine kinase inhibitor
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Accession:CHEBI:38637 term browser browse the term
Definition:Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
Synonyms:related_synonym: TKI inhibitor;   TKI inhibitors;   protein tyrosine kinase inhibitor;   protein tyrosine kinase inhibitors;   tyrosine kinase inhibitors;   tyrphostin;   tyrphostins
 xref: Wikipedia:Tyrosine-kinase_inhibitor


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    Path 1
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      CHEBI ontology 19900
        role 19875
          biological role 19873
            biochemical role 19567
              enzyme inhibitor 18735
                EC 2.* (transferase) inhibitor 14786
                  EC 2.7.* (P-containing group transferase) inhibitor 14260
                    protein kinase inhibitor 13853
                      tyrosine kinase inhibitor 11493
                        1-NA-PP1 0
                        1-NM-PP1 0
                        4,5-dianilinophthalimide 1
                        BE-23372M 0
                        DCC-2036 0
                        EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor + 9168
                        EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor + 1002
                        PD173955 + 0
                        PP121 0
                        SKLB-677 0
                        WZ4002 0
                        afatinib + 17
                        afatinib dimaleate 0
                        axitinib 8
                        biochanin A + 87
                        bosutinib + 22
                        bosutinib hydrate 0
                        butein 27
                        cabozantinib + 3
                        cabozantinib malate 0
                        canertinib 12
                        dasatinib (anhydrous) + 0
                        dasatinib monohydrate 0
                        emodin + 217
                        emodin(1-) 0
                        genistein + 3605
                        herbimycin 30
                        hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester 1
                        imatinib + 2
                        imatinib methanesulfonate 1
                        lapatinib 62
                        leflunomide 2627
                        masitinib 9
                        melemeleone B 0
                        neratinib 5
                        nilotinib 63
                        nintedanib 1
                        nintedanib esylate 0
                        pazopanib 18
                        pazopanib hydrochloride 0
                        piceatannol + 0
                        picropodophyllotoxin 16
                        ponatinib 77
                        ponatinib hydrochloride 0
                        radicicol 15
                        regorafenib + 22
                        regorafenib hydrate 0
                        sorafenib + 179
                        teriflunomide 43
                        vandetanib + 36
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