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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyclopiazonic acid
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Accession:CHEBI:38615 term browser browse the term
Synonyms:related_synonym: Cyclopiazonsaeuren;   Zyklopiazonsaeuren;   cyclopiazonic acids
 alt_id: CHEBI:23498;   CHEBI:23499


show annotations for term's descendants           Sort by:
(6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator decreases expression ISO cyclopiazonic acid results in decreased expression of BCL2 mRNA CTD PMID:33400354 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression		 EXP
ISO		 cyclopiazonic acid inhibits the reaction [Demecolcine results in increased activity of CASP3 protein]
cyclopiazonic acid results in increased expression of CASP3 mRNA		 CTD PMID:12530016 PMID:33400354 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 multiple interactions EXP cyclopiazonic acid inhibits the reaction [F2RL1 protein results in increased transport of Chlorides] CTD PMID:11804840 NCBI chr 5:76,819,030...76,835,315
Ensembl chr 5:76,818,933...76,835,315 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit affects response to substance ISO JUNB mRNA affects the susceptibility to cyclopiazonic acid CTD PMID:18716665 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 increases cleavage EXP cyclopiazonic acid results in increased cleavage of SPTAN1 protein CTD PMID:21516125 NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662 		JBrowse link
G STAR steroidogenic acute regulatory protein increases expression ISO cyclopiazonic acid results in increased expression of STAR protein CTD PMID:22001352 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992 		JBrowse link
G TP53 tumor protein p53 increases expression ISO cyclopiazonic acid results in increased expression of TRP53 mRNA CTD PMID:33400354 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538 		JBrowse link
G TP73 tumor protein p73 increases degradation EXP cyclopiazonic acid results in increased degradation of TP73 protein modified form CTD PMID:21516125 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26041
    role 25957
      biological role 25936
        poison 22509
          toxin 18390
            mycotoxin 13430
              cyclopiazonic acid 8
                alpha-cyclopiazonic acids + 8
                beta-cyclopiazonic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 26041
    subatomic particle 26016
      composite particle 26016
        hadron 26016
          baryon 26016
            nucleon 26016
              atomic nucleus 26016
                atom 26016
                  main group element atom 25841
                    p-block element atom 25841
                      carbon group element atom 25441
                        carbon atom 25399
                          organic molecular entity 25399
                            organic molecule 25228
                              organic cyclic compound 24281
                                organic heterocyclic compound 22324
                                  organic heteropolycyclic compound 21329
                                    organic heterobicyclic compound 18582
                                      benzopyrrole 10287
                                        indoles 9965
                                          cyclopiazonic acid 8
                                            alpha-cyclopiazonic acids + 8
                                            beta-cyclopiazonic acid + 0
paths to the root