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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyclopiazonic acid
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Accession:CHEBI:38615 term browser browse the term
Synonyms:related_synonym: Cyclopiazonsaeuren;   Zyklopiazonsaeuren;   cyclopiazonic acids
 alt_id: CHEBI:23498;   CHEBI:23499


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(6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO cyclopiazonic acid results in decreased expression of BCL2 mRNA CTD PMID:33400354 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression		 ISO cyclopiazonic acid inhibits the reaction [Demecolcine results in increased activity of CASP3 protein]
cyclopiazonic acid results in increased expression of CASP3 mRNA		 CTD PMID:12530016 PMID:33400354 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO cyclopiazonic acid inhibits the reaction [F2RL1 protein results in increased transport of Chlorides] CTD PMID:11804840 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects response to substance EXP JUNB mRNA affects the susceptibility to cyclopiazonic acid CTD PMID:18716665 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases cleavage ISO cyclopiazonic acid results in increased cleavage of SPTAN1 protein CTD PMID:21516125 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046 		JBrowse link
G Star steroidogenic acute regulatory protein increases expression EXP cyclopiazonic acid results in increased expression of STAR protein CTD PMID:22001352 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO cyclopiazonic acid results in increased expression of TRP53 mRNA CTD PMID:33400354 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp73 tumor protein p73 increases degradation ISO cyclopiazonic acid results in increased degradation of TP73 protein modified form CTD PMID:21516125 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20050
    role 20001
      biological role 20000
        poison 18475
          toxin 15296
            mycotoxin 11912
              cyclopiazonic acid 8
                alpha-cyclopiazonic acids + 8
                beta-cyclopiazonic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20050
    subatomic particle 20048
      composite particle 20048
        hadron 20048
          baryon 20048
            nucleon 20048
              atomic nucleus 20048
                atom 20048
                  main group element atom 19948
                    p-block element atom 19948
                      carbon group element atom 19872
                        carbon atom 19863
                          organic molecular entity 19863
                            organic molecule 19809
                              organic cyclic compound 19572
                                organic heterocyclic compound 18799
                                  organic heteropolycyclic compound 18274
                                    organic heterobicyclic compound 17169
                                      benzopyrrole 9604
                                        indoles 9277
                                          cyclopiazonic acid 8
                                            alpha-cyclopiazonic acids + 8
                                            beta-cyclopiazonic acid + 0
paths to the root