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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:cyclopentapyran
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Accession:CHEBI:38606 term browser browse the term
Synonyms:related_synonym: cyclopentapyrans


show annotations for term's descendants           Sort by:
loganin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO loganin results in decreased activity of ACHE protein CTD PMID:19666019 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] CTD PMID:35279615 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression ISO loganin results in increased expression of BCL2 mRNA CTD PMID:20966881 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 decreases expression ISO loganin results in decreased expression of CASP3 mRNA CTD PMID:20966881 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 decreases expression ISO loganin results in decreased expression of CASP9 mRNA CTD PMID:20966881 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression ISO loganin affects the expression of CCL2 protein CTD PMID:21864639 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cyba cytochrome b-245 alpha chain affects expression ISO loganin affects the expression of CYBA protein CTD PMID:21864639 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Hmox1 heme oxygenase 1 affects expression ISO loganin affects the expression of HMOX1 protein CTD PMID:21864639 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO		 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:35279615 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO		 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] CTD PMID:35279615 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Lep leptin affects expression ISO loganin affects the expression of LEP protein CTD PMID:21864639 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects expression ISO loganin affects the expression of NFE2L2 protein CTD PMID:21864639 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos2 nitric oxide synthase 2 affects expression ISO loganin affects the expression of NOS2 protein CTD PMID:21864639 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nox4 NADPH oxidase 4 affects expression ISO loganin affects the expression of NOX4 protein CTD PMID:21864639 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression ISO loganin affects the expression of PTGS2 protein CTD PMID:21864639 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects expression
multiple interactions		 ISO
EXP		 loganin affects the expression of RELA protein
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of RELA protein]		 CTD PMID:21864639 PMID:35279615 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP		 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT3 protein]
loganin inhibits the reaction [Lipopolysaccharides results in increased expression of STAT3 protein]		 CTD PMID:35279615 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO loganin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA] CTD PMID:35279615 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 loganin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] CTD PMID:35279615 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO loganin results in decreased expression of TNFSF11 mRNA CTD PMID:20966881 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
monotropein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO monotropein inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:23261679 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:23261679 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:23261679 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate affects the localization of NFKB1 protein]; monotropein inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein] CTD PMID:23261679 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases degradation		 ISO monotropein inhibits the reaction [Dextran Sulfate results in increased phosphorylation of NFKBIA protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
monotropein results in decreased degradation of NFKBIA protein		 CTD PMID:23261679 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate results in increased expression of NOS2 protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23261679 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate results in increased expression of PTGS2 protein]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:23261679 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO monotropein inhibits the reaction [Dextran Sulfate affects the localization of RELA protein]; monotropein inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:23261679 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; monotropein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:23261679 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19740
    chemical entity 19738
      atom 19738
        nonmetal atom 19678
          oxygen atom 19459
            oxygen molecular entity 19459
              organooxygen compound 19095
                oxacycle 17728
                  cyclopentapyran 24
                    7-deoxyloganetic acid + 0
                    7-deoxyloganetic alcohol 0
                    7-deoxyloganetic aldehyde 0
                    7-deoxyloganetin 0
                    7-deoxyloganic acid 0
                    agnuside 0
                    cis-cis-nepetalactol 0
                    cis-cis-nepetalactone 0
                    cis-trans-nepetalactol 0
                    cis-trans-nepetalactone 0
                    gardenoside 0
                    hastatoside 0
                    loganic acid 0
                    loganin + 20
                    monotropein 9
                    trans-cis-nepetalactone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      carbon group element atom 19631
                        carbon atom 19627
                          organic molecular entity 19627
                            organic molecule 19587
                              organic cyclic compound 19393
                                organic heterocyclic compound 18766
                                  organic heteropolycyclic compound 18254
                                    organic heterobicyclic compound 17226
                                      cyclopentapyran 24
                                        7-deoxyloganetic acid + 0
                                        7-deoxyloganetic alcohol 0
                                        7-deoxyloganetic aldehyde 0
                                        7-deoxyloganetin 0
                                        7-deoxyloganic acid 0
                                        agnuside 0
                                        cis-cis-nepetalactol 0
                                        cis-cis-nepetalactone 0
                                        cis-trans-nepetalactol 0
                                        cis-trans-nepetalactone 0
                                        gardenoside 0
                                        hastatoside 0
                                        loganic acid 0
                                        loganin + 20
                                        monotropein 9
                                        trans-cis-nepetalactone 0
paths to the root