CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: azamethiphos
Accession: CHEBI:38578
browse the term
Definition: An organochlorine acaricide that has formula C9H10ClN2O5PS.
Synonyms: exact_synonym: S-[(6-chloro-2-oxo[1,3]oxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl phosphorothioate
related_synonym: 6-chloro-3-dimethoxyphosphinoylthiomethyl-1,3-oxazolo(4,5-b)pyridin-2(3H)-one; Formula=C9H10ClN2O5PS; InChI=1S/C9H10ClN2O5PS/c1-15-18(14,16-2)19-5-12-8-7(17-9(12)13)3-6(10)4-11-8/h3-4H,5H2,1-2H3; InChIKey=VNKBTWQZTQIWDV-UHFFFAOYSA-N; S-((6-Chloro-2,3-dihydro-2-oxo-1,3-oxazolo-(4,5-b)pyridin-3-yl)methyl) O,O-dimethyl phosphorothioate; S-((6-chloro-2-oxooxazolo(4,5-b)pyridin-3(2H)-yl)methyl) O,O-dimethylphosphorothioate; S-6-chloro-2,3-dihydro-2-oxo-1,3-oxazolo(4,5-b)pyridin-3-ylmethyl O,O-dimethyl phosphorothioate; S-[(6-chloro-2-oxo[1,3]oxazolo[4,5-b]pyridin-3(2H)-yl)methyl] O,O-dimethyl thiophosphate; SMILES=COP(=O)(OC)SCn1c2ncc(Cl)cc2oc1=O
xref: Beilstein:1086470; CAS:35575-96-3; KEGG:C18702; KEGG:D07479
xref_mesh: MESH:C072763
xref: PPDB:48; VSDB:48
G
Ache
acetylcholinesterase
decreases activity
ISO EXP
azamethiphos results in decreased activity of ACHE protein
CTD
PMID:21251949
NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
G
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
multiple interactions
EXP
azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]
CTD
PMID:28385489
NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
G
Camk2b
calcium/calmodulin-dependent protein kinase II beta
multiple interactions
EXP
azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]
CTD
PMID:28385489
NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
G
Gap43
growth associated protein 43
multiple interactions
EXP
azamethiphos promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]
CTD
PMID:28385489
NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
G
Ngf
nerve growth factor
multiple interactions
EXP
azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2A mRNA]; azamethiphos promotes the reaction [NGF protein results in increased expression of CAMK2B mRNA]; azamethiphos promotes the reaction [NGF protein results in increased expression of GAP43 mRNA]
CTD
PMID:28385489
NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
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