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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid
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Accession:CHEBI:385425 term browser browse the term
Definition:A trisubstituted guanidine, carrying 4-cyanophenyl, diphenylmethyl and carboxymethyl substituents, which is known to act as a highly potent sweetening agent.
Synonyms:exact_synonym: (Z)-N-{[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylidene}glycine
 related_synonym: 2-[[(benzhydrylamino)-[(4-cyanophenyl)amino]methylidene]amino]ethanoic acid;   CP-Dpm-GA;   Formula=C23H20N4O2;   InChI=1S/C23H20N4O2/c24-15-17-11-13-20(14-12-17)26-23(25-16-21(28)29)27-22(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14,22H,16H2,(H,28,29)(H2,25,26,27);   InChIKey=KGHMYJFHUHFOGL-UHFFFAOYSA-N;   N-(4-Cyanophenyl)-N'-(diphenylmethyl)guanidineacetic acid;   N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID;   N-(p-Cyanophenyl)-N'-(diphenylmethyl)-N''-(carboxymethyl)guanidine;   NC-174;   SMILES=OC(=O)C\\N=C(\\NC(c1ccccc1)c1ccccc1)Nc1ccc(cc1)C#N
 alt_id: CHEBI:42679
 xref: CAS:138460-25-0;   DrugBank:DB07816
 xref_mesh: MESH:C083643
 xref: PDB:1ETZ;   PDB:2CGR;   PDBeChem:GAS;   PMID:10993728;   PMID:7893280;   PMID:9871559;   Reaxys:25965952


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[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnat3 G protein subunit alpha transducin 3 affects response to substance ISO GNAT3 protein affects the susceptibility to NC 174 CTD PMID:16740645 NCBI chr 4:13,827,764...13,878,126
Ensembl chr 4:13,827,756...13,878,126
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  CHEBI ontology 19853
    role 19804
      biological role 19804
        epitope 6845
          [N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic group 18550
                              organic divalent group 18541
                                organodiyl group 18541
                                  carbonyl group 18447
                                    carbonyl compound 18447
                                      carboxylic acid 18125
                                        amino acid 14110
                                          alpha-amino acid 11593
                                            L-alpha-amino acid 11430
                                              serine family amino acid 2057
                                                glycine 1212
                                                  glycine derivative 1201
                                                    [N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid 1
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