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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid
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Accession:CHEBI:385425 term browser browse the term
Definition:A trisubstituted guanidine, carrying 4-cyanophenyl, diphenylmethyl and carboxymethyl substituents, which is known to act as a highly potent sweetening agent.
Synonyms:exact_synonym: (Z)-N-{[(4-cyanophenyl)amino][(diphenylmethyl)amino]methylidene}glycine
 related_synonym: 2-[[(benzhydrylamino)-[(4-cyanophenyl)amino]methylidene]amino]ethanoic acid;   CP-Dpm-GA;   Formula=C23H20N4O2;   InChI=1S/C23H20N4O2/c24-15-17-11-13-20(14-12-17)26-23(25-16-21(28)29)27-22(18-7-3-1-4-8-18)19-9-5-2-6-10-19/h1-14,22H,16H2,(H,28,29)(H2,25,26,27);   InChIKey=KGHMYJFHUHFOGL-UHFFFAOYSA-N;   N-(4-Cyanophenyl)-N'-(diphenylmethyl)guanidineacetic acid;   N-(P-CYANOPHENYL)-N'-DIPHENYLMETHYL-GUANIDINE-ACETIC ACID;   N-(p-Cyanophenyl)-N'-(diphenylmethyl)-N''-(carboxymethyl)guanidine;   NC-174;   SMILES=OC(=O)C\\N=C(\\NC(c1ccccc1)c1ccccc1)Nc1ccc(cc1)C#N
 alt_id: CHEBI:42679
 xref: CAS:138460-25-0;   DrugBank:DB07816
 xref_mesh: MESH:C083643
 xref: PDB:1ETZ;   PDB:2CGR;   PDBeChem:GAS;   PMID:10993728;   PMID:7893280;   PMID:9871559;   Reaxys:25965952


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[N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnat3 G protein subunit alpha transducin 3 affects response to substance ISO GNAT3 protein affects the susceptibility to NC 174 CTD PMID:16740645 NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283 		JBrowse link
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Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    role 19825
      biological role 19823
        epitope 7030
          [N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19797
                    main group molecular entity 19797
                      s-block molecular entity 19629
                        hydrogen molecular entity 19610
                          hydrides 19121
                            inorganic hydride 18128
                              pnictogen hydride 18118
                                nitrogen hydride 18030
                                  azane 17835
                                    ammonia 17834
                                      organic amino compound 17834
                                        amino acid 16012
                                          alpha-amino acid 13872
                                            L-alpha-amino acid 12865
                                              serine family amino acid 5579
                                                glycine 3108
                                                  glycine derivative 3098
                                                    [N-(4-cyanophenyl)-N'-(diphenylmethyl)guanidine]acetic acid 1
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