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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:oxamyl
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Accession:CHEBI:38539 term browser browse the term
Definition:A carbamate ester that has formula C7H13N3O3S.
Synonyms:exact_synonym: methyl 2-(dimethylamino)-N-(methylcarbamoyloxy)-2-oxoethanimidothioate
 related_synonym: 2-(Dimethylamino)-N-(((methylamino)carbonyl)oxy)-2-oxoethanimidothioic acid methyl ester;   2-Dimethylamino-1-(methylthio)glyoxal O-methylcarbamoylmonoxime;   Dioxamyl;   Formula=C7H13N3O3S;   InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12);   InChIKey=KZAUOCCYDRDERY-UHFFFAOYSA-N;   N',N'-dimethyl-N-((methylcarbamoyl)oxy)-1-methylthio-oxamimidic acid;   N,N-Dimethyl-alpha-methylcarbamoyloxyimino-alpha-(methylthio)acetamide;   S-Methyl 1-(dimethylcarbamoyl)-N-((methylcarbamoyl)oxy)thioformimidate;   S-Methyl N',N'-dimethyl-N-(methylcarbamoyloxy)-1-thio-oxamimidate;   SMILES=CNC(=O)ON=C(SC)C(=O)N(C)C
 xref: Beilstein:2050910;   CAS:23135-22-0;   KEGG:C18419
 xref_mesh: MESH:C011960
 xref: PPDB:498



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oxamyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) decreases activity ISO
EXP
oxamyl results in decreased activity of ACHE protein CTD PMID:19934164 PMID:21251949 PMID:27132127 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G BCHE butyrylcholinesterase multiple interactions ISO [Carbaryl co-treated with Propoxur co-treated with Methiocarb co-treated with Methomyl co-treated with formetanate co-treated with oxamyl co-treated with Carbofuran] affects the activity of BCHE protein CTD PMID:22649187 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP oxamyl inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G PARK7 Parkinsonism associated deglycase decreases activity EXP oxamyl results in decreased activity of PARK7 protein CTD PMID:36842454 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PGR progesterone receptor multiple interactions EXP oxamyl inhibits the reaction [Progesterone results in increased activity of PGR protein] CTD PMID:9126867 NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
JBrowse link
G PON1 paraoxonase 1 multiple interactions EXP
ISO
[Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to oxamyl; [Egtazic Acid results in decreased activity of PON1 protein] which results in increased susceptibility to oxamyl
[Calcium results in increased activity of PON1 protein] which affects the susceptibility to oxamyl; [Egtazic Acid results in decreased activity of PON1 protein] which affects the susceptibility to oxamyl
CTD PMID:27132127 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532
JBrowse link
G TP53 tumor protein p53 affects activity EXP oxamyl metabolite affects the activity of TP53 protein CTD PMID:35435491 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      application 25172
        agrochemical 17514
          oxamyl 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    main group molecular entity 25834
                      s-block molecular entity 25166
                        hydrogen molecular entity 24765
                          hydrides 22965
                            inorganic hydride 20483
                              pnictogen hydride 20424
                                nitrogen hydride 20200
                                  azane 19942
                                    ammonia 19941
                                      organic amino compound 19941
                                        amino acid 17170
                                          methylcarbamic acid 87
                                            oxamyl 7
paths to the root