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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrrolizines
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Accession:CHEBI:38522 term browser browse the term


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Echimidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP echimidine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP echimidine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP echimidine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Casp3 caspase 3 multiple interactions ISO echimidine results in increased activity of and results in increased cleavage of CASP3 protein CTD PMID:29458164 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO echimidine results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:29458164 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity ISO echimidine results in increased activity of CASP9 protein CTD PMID:29458164 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP echimidine results in increased expression of CDKN1A mRNA CTD PMID:32419051 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression EXP echimidine results in increased expression of CKAP2 mRNA CTD PMID:32419051 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP echimidine results in decreased expression of CLEC4F mRNA CTD PMID:32419051 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP echimidine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression EXP echimidine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:66,560,200...66,602,509
Ensembl chr  X:66,561,286...66,602,506
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO echimidine metabolite results in increased expression of FAS mRNA CTD PMID:30465738 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases expression EXP echimidine results in decreased expression of HPGD mRNA CTD PMID:32419051 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression EXP echimidine results in increased expression of IFIT2 mRNA CTD PMID:32419051 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP echimidine results in decreased expression of INMT mRNA CTD PMID:32419051 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP echimidine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP echimidine results in increased expression of MKI67 mRNA CTD PMID:32419051 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP echimidine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO echimidine results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:29458164 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP echimidine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
Heliotrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO heliotrine results in decreased expression of ABCB11 mRNA CTD PMID:26100227 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP heliotrine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO heliotrine results in decreased expression of ABCC6 mRNA CTD PMID:26100227 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO
EXP
heliotrine results in decreased expression of ACSM3 mRNA CTD PMID:26100227, PMID:32419051 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP heliotrine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Aff3 AF4/FMR2 family, member 3 decreases expression ISO heliotrine results in decreased expression of AFF3 mRNA CTD PMID:26100227 NCBI chr 9:44,837,979...45,291,964
Ensembl chr 9:44,839,960...45,292,047
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression ISO heliotrine results in decreased expression of AGXT mRNA CTD PMID:26100227 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP heliotrine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases expression ISO heliotrine results in decreased expression of ALDH5A1 mRNA CTD PMID:26100227 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO heliotrine results in decreased expression of ALDH6A1 mRNA CTD PMID:26100227 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO heliotrine results in decreased expression of ALDH8A1 mRNA CTD PMID:26100227 NCBI chr 1:16,910,043...16,929,465
Ensembl chr 1:16,910,069...16,930,481
JBrowse link
G Areg amphiregulin increases expression ISO heliotrine results in increased expression of AREG mRNA CTD PMID:26100227 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP heliotrine results in increased expression of ATP6V1D mRNA CTD PMID:32419051 NCBI chr 6:102,032,271...102,047,754
Ensembl chr 6:102,032,276...102,047,758
JBrowse link
G Casp3 caspase 3 multiple interactions ISO heliotrine results in increased activity of and results in increased cleavage of CASP3 protein CTD PMID:29458164 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 increases cleavage ISO heliotrine results in increased cleavage of CASP8 protein CTD PMID:29458164 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity ISO heliotrine results in increased activity of CASP9 protein CTD PMID:29458164 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccng1 cyclin G1 increases expression EXP heliotrine results in increased expression of CCNG1 mRNA CTD PMID:32419051 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP heliotrine results in increased expression of CDKN1A mRNA CTD PMID:32419051 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression EXP heliotrine results in increased expression of CKAP2 mRNA CTD PMID:32419051 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP heliotrine results in decreased expression of CLEC4F mRNA CTD PMID:32419051 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP heliotrine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO heliotrine results in decreased expression of CYP3A5 mRNA CTD PMID:26100227 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression ISO heliotrine results in decreased expression of CYP4A22 mRNA CTD PMID:26100227 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases expression ISO heliotrine results in decreased expression of CYP4F3 mRNA CTD PMID:26100227 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO heliotrine results in decreased expression of CYP7A1 mRNA CTD PMID:26100227 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO heliotrine results in decreased expression of CYP8B1 mRNA CTD PMID:26100227 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases expression EXP heliotrine results in increased expression of CYRIA mRNA CTD PMID:32419051 NCBI chr 6:37,555,167...37,661,196
Ensembl chr 6:37,555,182...37,665,064
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor increases expression EXP heliotrine results in increased expression of DDIAS mRNA CTD PMID:32419051 NCBI chr 1:157,675,754...157,700,064
Ensembl chr 1:157,675,765...157,700,064
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression ISO heliotrine results in increased expression of DHRS9 mRNA CTD PMID:26100227 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression ISO heliotrine results in decreased expression of DPYD mRNA CTD PMID:26100227 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression EXP heliotrine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:66,560,200...66,602,509
Ensembl chr  X:66,561,286...66,602,506
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP heliotrine results in increased expression of EPHX1 mRNA CTD PMID:32419051 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO heliotrine results in decreased expression of EPHX2 mRNA CTD PMID:26100227 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO
EXP
heliotrine metabolite results in increased expression of FAS mRNA
heliotrine results in increased expression of FAS mRNA
CTD PMID:30465738, PMID:32419051 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 decreases expression ISO heliotrine results in decreased expression of FMO3 mRNA CTD PMID:26100227 NCBI chr13:80,837,418...80,856,214
Ensembl chr13:80,837,420...80,862,963
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 decreases expression ISO heliotrine results in decreased expression of FMO4 mRNA CTD PMID:26100227 NCBI chr13:80,685,385...80,703,575
Ensembl chr13:80,685,325...80,703,615
JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO heliotrine results in decreased expression of GAMT mRNA CTD PMID:26100227 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO heliotrine results in increased expression of GEM mRNA CTD PMID:26100227 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gls glutaminase increases expression ISO heliotrine results in increased expression of GLS mRNA CTD PMID:26100227 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Glyat glycine-N-acyltransferase decreases expression ISO heliotrine results in decreased expression of GLYAT mRNA CTD PMID:26100227 NCBI chr 1:229,060,125...229,081,113
Ensembl chr 1:229,063,714...229,080,410
JBrowse link
G Gphn gephyrin decreases expression ISO heliotrine results in decreased expression of GPHN mRNA CTD PMID:26100227 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A increases expression ISO heliotrine results in increased expression of GPRC5A mRNA CTD PMID:26100227 NCBI chr 4:168,832,937...168,851,650
Ensembl chr 4:168,832,910...168,851,652
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP heliotrine results in increased expression of GRIA3 mRNA CTD PMID:32419051 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO heliotrine results in decreased expression of HNMT mRNA CTD PMID:26100227 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 increases expression EXP heliotrine results in increased expression of HSD17B13 mRNA CTD PMID:32419051 NCBI chr14:7,113,544...7,128,218
Ensembl chr14:7,113,544...7,128,218
JBrowse link
G Il17rd interleukin 17 receptor D increases expression EXP heliotrine results in increased expression of IL17RD mRNA CTD PMID:32419051 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP heliotrine results in decreased expression of INMT mRNA CTD PMID:32419051 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression ISO heliotrine results in increased expression of ISG20 mRNA CTD PMID:26100227 NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946
JBrowse link
G Jam3 junctional adhesion molecule 3 increases expression EXP heliotrine results in increased expression of JAM3 mRNA CTD PMID:32419051 NCBI chr 8:28,147,110...28,208,466
Ensembl chr 8:28,147,111...28,208,466
JBrowse link
G LOC100911204 protein CASC5-like increases expression EXP heliotrine results in increased expression of KNL1 mRNA CTD PMID:32419051 NCBI chr 3:112,531,429...112,560,698
Ensembl chr 3:112,531,703...112,560,634
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO heliotrine results in increased expression of MAFF mRNA CTD PMID:26100227 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Maoa monoamine oxidase A decreases expression ISO heliotrine results in decreased expression of MAOA mRNA CTD PMID:26100227 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Maob monoamine oxidase B decreases expression ISO heliotrine results in decreased expression of MAOB mRNA CTD PMID:26100227 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like increases expression EXP heliotrine results in increased expression of MASTL mRNA CTD PMID:32419051 NCBI chr17:89,839,562...89,875,855
Ensembl chr17:89,742,140...89,876,825
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP heliotrine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP heliotrine results in increased expression of MKI67 mRNA CTD PMID:32419051 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO heliotrine results in increased expression of MMP1 mRNA CTD PMID:26100227 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mok MOK protein kinase increases expression EXP heliotrine results in increased expression of MOK mRNA CTD PMID:32419051 NCBI chr 6:135,228,755...135,259,645
Ensembl chr 6:135,228,803...135,259,603
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP heliotrine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression EXP heliotrine results in increased expression of MYBL2 mRNA CTD PMID:32419051 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Neb nebulin decreases expression ISO heliotrine results in decreased expression of NEB mRNA CTD PMID:26100227 NCBI chr 3:37,658,081...37,855,843
Ensembl chr 3:37,658,563...37,854,561
JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression ISO heliotrine results in decreased expression of NNMT mRNA CTD PMID:26100227 NCBI chr 8:52,918,437...52,938,172
Ensembl chr 8:52,925,175...52,937,972
JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression EXP heliotrine results in increased expression of NRCAM mRNA CTD PMID:32419051 NCBI chr 6:64,297,843...64,867,408
Ensembl chr 6:64,297,888...64,864,996
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP heliotrine results in increased expression of NRG1 mRNA CTD PMID:32419051 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO heliotrine results in decreased expression of PARP1 protein CTD PMID:29458164 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression ISO heliotrine results in decreased expression of PTPRD mRNA CTD PMID:26100227 NCBI chr 5:92,862,229...93,514,071
Ensembl chr 5:92,862,267...93,244,202
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO heliotrine results in decreased expression of RAPGEF4 mRNA CTD PMID:26100227 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO heliotrine results in increased expression of RRAD mRNA CTD PMID:26100227 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G Sgcb sarcoglycan, beta increases expression EXP heliotrine results in increased expression of SGCB mRNA CTD PMID:32419051 NCBI chr14:37,113,194...37,128,623
Ensembl chr14:37,113,210...37,128,737
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO heliotrine results in decreased expression of SLC10A1 mRNA CTD PMID:26100227 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc22a25 solute carrier family 22, member 25 decreases expression ISO heliotrine results in decreased expression of SLC22A9 mRNA CTD PMID:26100227 NCBI chr 1:224,596,886...224,698,512
Ensembl chr 1:224,596,887...224,698,514
JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression ISO heliotrine results in decreased expression of SLC22A7 mRNA CTD PMID:26100227 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression ISO heliotrine results in decreased expression of SLCO2B1 mRNA CTD PMID:26100227 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP heliotrine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases expression ISO heliotrine results in decreased expression of SULT1E1 mRNA CTD PMID:26100227 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression ISO heliotrine results in decreased expression of SULT2A1 mRNA CTD PMID:26100227 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tenm1 teneurin transmembrane protein 1 decreases expression ISO heliotrine results in decreased expression of TENM1 mRNA CTD PMID:26100227 NCBI chr  X:129,034,755...129,336,023
NCBI chr  X:128,923,951...128,951,520
JBrowse link
G Tenm2 teneurin transmembrane protein 2 decreases expression ISO heliotrine results in decreased expression of TENM2 mRNA CTD PMID:26100227 NCBI chr10:20,846,091...21,791,771
Ensembl chr10:20,844,899...21,265,026
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP heliotrine results in increased expression of TOP2A mRNA CTD PMID:32419051 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tyms thymidylate synthetase increases expression EXP heliotrine results in increased expression of TYMS mRNA CTD PMID:32419051 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Ugt3a2 UDP glycosyltransferase 3 family, polypeptide A2 decreases expression ISO heliotrine results in decreased expression of UGT3A1 mRNA CTD PMID:26100227 NCBI chr 2:58,666,337...58,682,212
Ensembl chr 2:58,668,157...58,681,747
JBrowse link
G Vps13b vacuolar protein sorting 13 homolog B decreases expression ISO heliotrine results in decreased expression of VPS13B mRNA CTD PMID:26100227 NCBI chr 7:74,118,834...74,722,341 JBrowse link
ketorolac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP Ketorolac results in decreased expression of CXCL1 mRNA CTD PMID:19620882 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions ISO Ketorolac inhibits the reaction [IL4 results in increased expression of CYSLTR1 mRNA] CTD PMID:19767084 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression ISO Ketorolac results in decreased expression of EPAS1 protein CTD PMID:12912967 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia multiple interactions ISO Ketorolac inhibits the reaction [IL4 results in increased expression of FCER1A mRNA] CTD PMID:19767084 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Ketorolac inhibits the reaction [IL1B protein results in increased expression of FOS mRNA] CTD PMID:10800959 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Ketorolac results in decreased expression of HIF1A protein CTD PMID:12912967 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP Ketorolac results in decreased expression of ICAM1 mRNA CTD PMID:19620882 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Ketorolac co-treated with IL1B protein] results in increased secretion of Dinoprostone; Ketorolac inhibits the reaction [IL1B protein results in increased expression of FOS mRNA]; Ketorolac inhibits the reaction [IL1B protein results in increased expression of NR4A1 mRNA]; Ketorolac inhibits the reaction [IL1B protein results in increased expression of PTGER4 mRNA]; Ketorolac inhibits the reaction [IL1B protein results in increased secretion of Corticosterone] CTD PMID:10800959 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Ketorolac inhibits the reaction [IL4 results in increased activity of STAT6 protein]; Ketorolac inhibits the reaction [IL4 results in increased expression of CYSLTR1 mRNA]; Ketorolac inhibits the reaction [IL4 results in increased expression of FCER1A mRNA]; Ketorolac inhibits the reaction [IL4 results in increased phosphorylation of STAT6 protein] CTD PMID:19767084 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like affects expression ISO Ketorolac affects the expression of HLA-A mRNA CTD PMID:25811541 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G Mpo myeloperoxidase decreases activity EXP Ketorolac results in decreased activity of MPO CTD PMID:11996850 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions EXP Ketorolac inhibits the reaction [IL1B protein results in increased expression of NR4A1 mRNA] CTD PMID:10800959 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions EXP Ketorolac inhibits the reaction [IL1B protein results in increased expression of PTGER4 mRNA] CTD PMID:10800959 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression
decreases activity
ISO Ketorolac results in decreased expression of PTGS1 mRNA
Ketorolac results in decreased activity of PTGS1 protein
CTD PMID:17175104 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
decreases expression
ISO
EXP
Ketorolac results in increased expression of PTGS2 mRNA
Ketorolac inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]]
Ketorolac results in decreased expression of PTGS2 mRNA
CTD PMID:17175104, PMID:17258197, PMID:19620882 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression ISO Ketorolac affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G Sele selectin E decreases expression EXP Ketorolac results in decreased expression of SELE mRNA CTD PMID:19620882 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions ISO Ketorolac inhibits the reaction [IL4 results in increased activity of STAT6 protein]; Ketorolac inhibits the reaction [IL4 results in increased phosphorylation of STAT6 protein] CTD PMID:19767084 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO Ketorolac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Ketorolac inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Aldosterone] CTD PMID:19740398 NCBI chr14:22,597,103...22,619,968 JBrowse link
Lasiocarpine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO lasiocarpine results in decreased expression of ABCB11 mRNA CTD PMID:32234424 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP lasiocarpine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ace angiotensin I converting enzyme decreases expression ISO lasiocarpine metabolite results in decreased expression of ACE mRNA CTD PMID:30465738 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP lasiocarpine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 increases expression ISO lasiocarpine results in increased expression of ADGRG1 mRNA CTD PMID:32234424 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO lasiocarpine results in decreased expression of ADH4 mRNA CTD PMID:32234424 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Akap5 A-kinase anchoring protein 5 increases expression ISO lasiocarpine results in increased expression of AKAP5 mRNA CTD PMID:32234424 NCBI chr 6:99,356,509...99,361,909
Ensembl chr 6:99,356,509...99,361,909
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 decreases expression ISO lasiocarpine results in decreased expression of AKR1D1 mRNA CTD PMID:32234424 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP lasiocarpine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression ISO lasiocarpine results in decreased expression of ALPI mRNA CTD PMID:32234424 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Angpt1 angiopoietin 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of ANGPT1 mRNA CTD PMID:30465738 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Arg1 arginase 1 decreases expression ISO lasiocarpine results in decreased expression of ARG1 mRNA CTD PMID:32234424 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arl14 ADP-ribosylation factor like GTPase 14 increases expression ISO lasiocarpine results in increased expression of ARL14 mRNA CTD PMID:32234424 NCBI chr 2:165,835,196...165,836,291
Ensembl chr 2:165,835,701...165,836,279
JBrowse link
G Aspdh aspartate dehydrogenase domain containing decreases expression ISO lasiocarpine results in decreased expression of ASPDH mRNA CTD PMID:32234424 NCBI chr 1:100,471,066...100,473,327
Ensembl chr 1:100,470,722...100,473,459
JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 decreases expression ISO lasiocarpine results in decreased expression of ASPRV1 mRNA CTD PMID:32234424 NCBI chr 4:118,431,755...118,433,286
Ensembl chr 4:118,431,755...118,432,775
JBrowse link
G Aunip aurora kinase A and ninein interacting protein increases expression ISO lasiocarpine results in increased expression of AUNIP mRNA CTD PMID:32234424 NCBI chr 5:152,721,799...152,734,577
Ensembl chr 5:152,721,940...152,734,572
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression EXP lasiocarpine results in decreased expression of AXL mRNA CTD PMID:32419051 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO lasiocarpine results in decreased expression of BDH1 mRNA CTD PMID:32234424 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Blm BLM RecQ like helicase increases expression ISO lasiocarpine results in increased expression of BLM mRNA CTD PMID:32234424 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO lasiocarpine results in increased expression of BRCA1 mRNA CTD PMID:32234424 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression ISO lasiocarpine results in increased expression of BRCA2 mRNA CTD PMID:32234424 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Casp16 caspase 16 decreases expression ISO lasiocarpine results in decreased expression of CASP16P mRNA CTD PMID:32234424 NCBI chr10:12,878,933...12,885,492 JBrowse link
G Ccdc152 coiled-coil domain containing 152 increases expression ISO lasiocarpine results in increased expression of CCDC152 mRNA CTD PMID:32234424 NCBI chr 2:53,116,105...53,140,661
Ensembl chr 2:53,116,101...53,140,637
JBrowse link
G Ccne2 cyclin E2 increases expression ISO lasiocarpine results in increased expression of CCNE2 mRNA CTD PMID:32234424 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng1 cyclin G1 increases expression EXP lasiocarpine results in increased expression of CCNG1 mRNA CTD PMID:32419051 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd83 CD83 molecule increases expression ISO lasiocarpine results in increased expression of CD83 mRNA CTD PMID:32234424 NCBI chr17:24,416,651...24,435,790
Ensembl chr17:24,416,651...24,435,790
JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO lasiocarpine results in increased expression of CDC25A mRNA CTD PMID:32234424 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdc42bpg CDC42 binding protein kinase gamma increases expression ISO lasiocarpine results in increased expression of CDC42BPG mRNA CTD PMID:32234424 NCBI chr 1:221,673,334...221,693,518
Ensembl chr 1:221,673,590...221,693,518
JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO lasiocarpine results in increased expression of CDC45 mRNA CTD PMID:32234424 NCBI chr11:86,328,785...86,354,099
Ensembl chr11:86,329,012...86,358,453
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO lasiocarpine results in increased expression of CDC6 mRNA CTD PMID:32234424 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdc7 cell division cycle 7 increases expression ISO lasiocarpine results in increased expression of CDC7 mRNA CTD PMID:32234424 NCBI chr14:3,826,658...3,846,891
Ensembl chr14:3,826,659...3,846,891
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP lasiocarpine results in increased expression of CDKN1A mRNA CTD PMID:32419051 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 increases expression ISO lasiocarpine results in increased expression of CDT1 mRNA CTD PMID:32234424 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
JBrowse link
G Cel carboxyl ester lipase increases expression ISO lasiocarpine results in increased expression of CEL mRNA CTD PMID:32234424 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Cldn14 claudin 14 decreases expression ISO lasiocarpine results in decreased expression of CLDN14 mRNA CTD PMID:32234424 NCBI chr11:34,132,581...34,142,813
Ensembl chr11:34,132,581...34,142,753
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP lasiocarpine results in decreased expression of CLEC4F mRNA CTD PMID:32419051 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Clspn claspin increases expression ISO lasiocarpine results in increased expression of CLSPN mRNA CTD PMID:32234424 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335
JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO lasiocarpine results in decreased expression of COL5A2 mRNA CTD PMID:32234424 NCBI chr 9:52,091,088...52,238,735
Ensembl chr 9:52,092,511...52,238,564
JBrowse link
G Crppa CDP-L-ribitol pyrophosphorylase A decreases expression ISO lasiocarpine results in decreased expression of CRPPA mRNA CTD PMID:32234424 NCBI chr 6:55,880,136...56,159,466
Ensembl chr 6:55,881,387...56,159,464
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP lasiocarpine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression ISO lasiocarpine results in decreased expression of CYBA mRNA CTD PMID:32234424 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO lasiocarpine results in increased expression of CYP1A1 mRNA CTD PMID:32234424 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression ISO lasiocarpine results in decreased expression of CYP2A7 mRNA CTD PMID:32234424 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO lasiocarpine results in decreased expression of CYP2E1 mRNA CTD PMID:32234424 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing EXP CYP3A2 protein results in increased metabolism of lasiocarpine CTD PMID:31103741 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases metabolic processing EXP CYP3A23-3A1 protein results in increased metabolism of lasiocarpine CTD PMID:31103741 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing ISO CYP3A5 protein results in increased metabolism of lasiocarpine CTD PMID:31103741 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO lasiocarpine results in decreased expression of CYP7A1 mRNA CTD PMID:32234424 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases expression EXP lasiocarpine results in increased expression of CYRIA mRNA CTD PMID:32419051 NCBI chr 6:37,555,167...37,661,196
Ensembl chr 6:37,555,182...37,665,064
JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 increases expression ISO lasiocarpine results in increased expression of DSCC1 mRNA CTD PMID:32234424 NCBI chr 7:94,759,076...94,774,787
Ensembl chr 7:94,758,800...94,774,569
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog increases expression ISO lasiocarpine results in increased expression of DTL mRNA CTD PMID:32234424 NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO lasiocarpine results in increased expression of E2F2 mRNA CTD PMID:32234424 NCBI chr 5:154,516,611...154,540,228
Ensembl chr 5:154,522,119...154,540,265
JBrowse link
G E2f7 E2F transcription factor 7 increases expression ISO lasiocarpine results in increased expression of E2F7 mRNA CTD PMID:32234424 NCBI chr 7:53,275,659...53,318,261
Ensembl chr 7:53,275,676...53,316,481
JBrowse link
G E2f8 E2F transcription factor 8 increases expression ISO lasiocarpine results in increased expression of E2F8 mRNA CTD PMID:32234424 NCBI chr 1:104,185,436...104,203,683
Ensembl chr 1:104,187,100...104,202,591
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression EXP lasiocarpine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:66,560,200...66,602,509
Ensembl chr  X:66,561,286...66,602,506
JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 decreases expression ISO lasiocarpine results in decreased expression of ENOX1 mRNA CTD PMID:32234424 NCBI chr15:59,331,134...59,884,512
Ensembl chr15:59,678,165...59,884,511
JBrowse link
G Exo1 exonuclease 1 increases expression ISO lasiocarpine results in increased expression of EXO1 mRNA CTD PMID:32234424 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO lasiocarpine results in decreased expression of FABP1 mRNA CTD PMID:32234424 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fam151a family with sequence similarity 151, member A decreases expression ISO lasiocarpine results in decreased expression of FAM151A mRNA CTD PMID:32234424 NCBI chr 5:126,334,847...126,347,598
Ensembl chr 5:126,334,803...126,347,770
JBrowse link
G Fancg FA complementation group G increases expression ISO lasiocarpine results in increased expression of FANCG mRNA CTD PMID:32234424 NCBI chr 5:58,448,060...58,456,416
Ensembl chr 5:58,448,822...58,455,819
JBrowse link
G Fanci FA complementation group I increases expression ISO lasiocarpine results in increased expression of FANCI mRNA CTD PMID:32234424 NCBI chr 1:141,116,565...141,172,997
Ensembl chr 1:141,120,166...141,172,483
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO lasiocarpine metabolite results in increased expression of FAS mRNA CTD PMID:30465738 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fcna ficolin A decreases expression EXP lasiocarpine results in decreased expression of FCNA mRNA CTD PMID:32419051 NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272
JBrowse link
G Fendrr FOXF1 adjacent non-coding developmental regulatory RNA increases expression ISO lasiocarpine results in increased expression of FENDRR mRNA CTD PMID:32234424 NCBI chr19:52,991,283...53,010,509 JBrowse link
G Fgf13 fibroblast growth factor 13 decreases expression ISO lasiocarpine results in decreased expression of FGF13 mRNA CTD PMID:32234424 NCBI chr  X:142,053,648...142,589,274
Ensembl chr  X:142,053,654...142,248,369
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO lasiocarpine metabolite results in decreased expression of FGF2 mRNA CTD PMID:30465738 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression ISO lasiocarpine results in decreased expression of FHIT mRNA CTD PMID:32234424 NCBI chr15:15,697,292...16,862,873 JBrowse link
G Fn1 fibronectin 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of FN1 mRNA CTD PMID:30465738 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO lasiocarpine results in increased expression of FOSL1 mRNA CTD PMID:32234424 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO lasiocarpine results in decreased expression of G6PC mRNA CTD PMID:32234424 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO lasiocarpine results in increased expression of GDF15 mRNA CTD PMID:32234424 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression ISO lasiocarpine results in decreased expression of GNMT mRNA CTD PMID:32234424 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Gpc6 glypican 6 decreases expression ISO lasiocarpine results in decreased expression of GPC6 mRNA CTD PMID:32234424 NCBI chr15:102,164,091...103,174,721
Ensembl chr15:102,164,751...103,170,847
JBrowse link
G Gpr161 G protein-coupled receptor 161 increases expression ISO lasiocarpine results in increased expression of GPR161 mRNA CTD PMID:32234424 NCBI chr13:83,530,389...83,576,117
Ensembl chr13:83,531,018...83,571,505
JBrowse link
G Gpt glutamic--pyruvic transaminase affects activity EXP lasiocarpine affects the activity of GPT protein CTD PMID:32419051 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grap2 GRB2-related adaptor protein 2 increases expression ISO lasiocarpine results in increased expression of GRAP2 mRNA CTD PMID:32234424 NCBI chr 7:121,791,330...121,864,835
Ensembl chr 7:121,841,855...121,864,679
JBrowse link
G Gucy2d guanylate cyclase 2D, retinal decreases expression ISO lasiocarpine results in decreased expression of GUCY2D mRNA CTD PMID:32234424 NCBI chr10:55,835,695...55,851,235
Ensembl chr10:55,835,695...55,851,235
JBrowse link
G Gzma granzyme A decreases expression EXP lasiocarpine results in decreased expression of GZMA mRNA CTD PMID:32419051 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Hells helicase, lymphoid specific increases expression ISO lasiocarpine results in increased expression of HELLS mRNA CTD PMID:32234424 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Hhat hedgehog acyltransferase decreases expression ISO lasiocarpine results in decreased expression of HHAT mRNA CTD PMID:32234424 NCBI chr13:111,235,325...111,489,075
Ensembl chr13:111,236,466...111,474,411
JBrowse link
G Hjv hemojuvelin BMP co-receptor decreases expression ISO lasiocarpine results in decreased expression of HJV mRNA CTD PMID:32234424 NCBI chr 2:198,655,437...198,659,318
Ensembl chr 2:198,655,437...198,659,317
JBrowse link
G Hmcn1 hemicentin 1 decreases expression ISO lasiocarpine results in decreased expression of HMCN1 mRNA CTD PMID:32234424 NCBI chr13:67,799,791...68,360,664
Ensembl chr13:67,799,791...68,360,664
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases expression EXP lasiocarpine results in decreased expression of HPGD mRNA CTD PMID:32419051 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hs6st3 heparan sulfate 6-O-sulfotransferase 3 decreases expression ISO lasiocarpine results in decreased expression of HS6ST3 mRNA CTD PMID:32234424 NCBI chr15:104,448,479...105,254,540
Ensembl chr15:104,448,600...105,254,214
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 increases expression EXP lasiocarpine results in increased expression of HSD17B13 mRNA CTD PMID:32419051 NCBI chr14:7,113,544...7,128,218
Ensembl chr14:7,113,544...7,128,218
JBrowse link
G Igsf23 immunoglobulin superfamily, member 23 decreases expression ISO lasiocarpine results in decreased expression of IGSF23 mRNA CTD PMID:32234424 NCBI chr 1:80,850,783...80,869,481
Ensembl chr 1:80,852,528...80,864,846
JBrowse link
G Il11 interleukin 11 increases expression ISO lasiocarpine metabolite results in increased expression of IL11 mRNA CTD PMID:30465738 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il17rd interleukin 17 receptor D increases expression EXP lasiocarpine results in increased expression of IL17RD mRNA CTD PMID:32419051 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Il1b interleukin 1 beta increases expression ISO lasiocarpine metabolite results in increased expression of IL1B mRNA CTD PMID:30465738 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 decreases expression ISO lasiocarpine results in decreased expression of IMMP2L mRNA CTD PMID:32234424 NCBI chr 6:60,958,351...61,859,457 JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression ISO lasiocarpine results in increased expression of INPP5D mRNA CTD PMID:32234424 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771
JBrowse link
G Itga8 integrin subunit alpha 8 decreases expression ISO lasiocarpine results in decreased expression of ITGA8 mRNA CTD PMID:32234424 NCBI chr17:79,321,893...79,676,927
Ensembl chr17:79,321,900...79,676,499
JBrowse link
G Jam3 junctional adhesion molecule 3 increases expression EXP lasiocarpine results in increased expression of JAM3 mRNA CTD PMID:32419051 NCBI chr 8:28,147,110...28,208,466
Ensembl chr 8:28,147,111...28,208,466
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 decreases expression ISO lasiocarpine results in decreased expression of KCNMA1 mRNA CTD PMID:32234424 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Kmo kynurenine 3-monooxygenase decreases expression ISO lasiocarpine results in decreased expression of KMO mRNA CTD PMID:32234424 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 increases expression ISO lasiocarpine results in increased expression of LAMP3 mRNA CTD PMID:32234424 NCBI chr11:84,930,965...85,000,694
Ensembl chr11:84,972,132...85,000,681
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO lasiocarpine results in increased expression of LIF mRNA CTD PMID:32234424 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lingo4 leucine rich repeat and Ig domain containing 4 decreases expression ISO lasiocarpine results in decreased expression of LINGO4 mRNA CTD PMID:32234424 NCBI chr 2:195,617,044...195,643,502
Ensembl chr 2:195,617,044...195,643,502
JBrowse link
G LOC498265 similar to hypothetical protein FLJ10706 increases expression ISO lasiocarpine results in increased expression of C1ORF112 mRNA CTD PMID:32234424 NCBI chr13:82,254,516...82,298,467
Ensembl chr13:82,254,453...82,298,404
JBrowse link
G Lrmda leucine rich melanocyte differentiation associated decreases expression ISO lasiocarpine results in decreased expression of LRMDA mRNA CTD PMID:32234424 NCBI chr15:1,269,869...2,346,246 JBrowse link
G Lrrc39 leucine rich repeat containing 39 decreases expression ISO lasiocarpine results in decreased expression of LRRC39 mRNA CTD PMID:32234424 NCBI chr 2:219,598,162...219,617,498
Ensembl chr 2:219,598,162...219,617,498
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 increases expression ISO lasiocarpine results in increased expression of LZTS1 mRNA CTD PMID:32234424 NCBI chr16:22,250,452...22,306,667
Ensembl chr16:22,250,470...22,306,662
JBrowse link
G Mab21l4 mab-21 like 4 decreases expression ISO lasiocarpine results in decreased expression of MAB21L4 mRNA CTD PMID:32234424 NCBI chr 9:100,296,780...100,307,415
Ensembl chr 9:100,296,781...100,306,829
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 decreases expression ISO lasiocarpine results in decreased expression of MACROD2 mRNA CTD PMID:32234424 NCBI chr 3:135,729,839...136,422,082 JBrowse link
G Mbl2 mannose binding lectin 2 decreases expression ISO lasiocarpine results in decreased expression of MBL2 mRNA CTD PMID:32234424 NCBI chr 1:248,435,069...248,442,669
Ensembl chr 1:248,723,397...248,729,962
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor increases expression ISO lasiocarpine results in increased expression of MCM10 mRNA CTD PMID:32234424 NCBI chr17:77,224,218...77,245,486
Ensembl chr17:77,224,112...77,246,478
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP lasiocarpine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mnd1 meiotic nuclear divisions 1 increases expression ISO lasiocarpine results in increased expression of MND1 mRNA CTD PMID:32234424 NCBI chr 2:183,073,029...183,140,768
Ensembl chr 2:183,073,187...183,128,932
JBrowse link
G Mpp2 membrane palmitoylated protein 2 increases expression ISO lasiocarpine results in increased expression of MPP2 mRNA CTD PMID:32234424 NCBI chr10:89,998,284...90,030,766
Ensembl chr10:89,999,917...90,030,639
JBrowse link
G Muc13 mucin 13, cell surface associated increases expression ISO lasiocarpine results in increased expression of MUC13 mRNA CTD PMID:32234424 NCBI chr11:70,185,757...70,223,012
Ensembl chr11:70,185,757...70,211,701
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP lasiocarpine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression ISO
EXP
lasiocarpine results in increased expression of MYBL2 mRNA CTD PMID:32234424, PMID:32419051 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Myo10 myosin X increases expression ISO lasiocarpine results in increased expression of MYO10 mRNA CTD PMID:32234424 NCBI chr 2:77,868,398...78,072,443
Ensembl chr 2:77,868,412...78,071,309
JBrowse link
G Naaladl2 N-acetylated alpha-linked acidic dipeptidase-like 2 decreases expression ISO lasiocarpine results in decreased expression of NAALADL2 mRNA CTD PMID:32234424 NCBI chr 2:109,092,931...110,424,885 JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO lasiocarpine results in increased expression of NCF2 mRNA CTD PMID:32234424 NCBI chr13:70,226,441...70,259,019
Ensembl chr13:70,226,647...70,257,576
JBrowse link
G Nectin4 nectin cell adhesion molecule 4 increases expression ISO lasiocarpine results in increased expression of NECTIN4 mRNA CTD PMID:32234424 NCBI chr13:89,755,665...89,774,185
Ensembl chr13:89,755,845...89,774,378
JBrowse link
G Ninl ninein-like decreases expression ISO lasiocarpine results in decreased expression of NINL mRNA CTD PMID:32234424 NCBI chr 3:146,719,210...146,785,450
Ensembl chr 3:146,719,911...146,764,015
JBrowse link
G Npas3 neuronal PAS domain protein 3 decreases expression ISO lasiocarpine results in decreased expression of NPAS3 mRNA CTD PMID:32234424 NCBI chr 6:74,081,995...74,913,025 JBrowse link
G Npr1 natriuretic peptide receptor 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of NPR1 mRNA CTD PMID:30465738 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO lasiocarpine results in decreased expression of NR0B2 mRNA CTD PMID:32234424 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression ISO lasiocarpine results in decreased expression of NR1I3 mRNA CTD PMID:32234424 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression EXP lasiocarpine results in increased expression of NRCAM mRNA CTD PMID:32419051 NCBI chr 6:64,297,843...64,867,408
Ensembl chr 6:64,297,888...64,864,996
JBrowse link
G Nrgn neurogranin increases expression ISO lasiocarpine results in increased expression of NRGN mRNA CTD PMID:32234424 NCBI chr 8:40,015,049...40,023,193
Ensembl chr 8:40,015,049...40,023,193
JBrowse link
G Nts neurotensin decreases expression ISO lasiocarpine results in decreased expression of NTS mRNA CTD PMID:32234424 NCBI chr 7:44,111,594...44,120,998
Ensembl chr 7:44,111,151...44,121,130
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP lasiocarpine results in increased expression of NUPR1 mRNA CTD PMID:32419051 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression ISO lasiocarpine results in increased expression of ORC1 mRNA CTD PMID:32234424 NCBI chr 5:128,186,651...128,212,901
Ensembl chr 5:128,190,708...128,210,445
JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 decreases expression ISO lasiocarpine results in decreased expression of PAK5 mRNA CTD PMID:32234424 NCBI chr 3:129,042,232...129,357,512
Ensembl chr 3:129,042,742...129,357,491
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of PECAM1 mRNA CTD PMID:30465738 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 decreases expression ISO lasiocarpine results in decreased expression of PFKFB1 mRNA CTD PMID:32234424 NCBI chr  X:23,092,143...23,145,923
Ensembl chr  X:23,092,159...23,144,324
JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 decreases expression ISO lasiocarpine results in decreased expression of PGLYRP2 mRNA CTD PMID:32234424 NCBI chr 7:14,426,481...14,435,987
Ensembl chr 7:14,429,701...14,435,967
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO lasiocarpine results in decreased expression of PKLR mRNA CTD PMID:32234424 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Plg plasminogen decreases expression ISO lasiocarpine results in decreased expression of PLG mRNA CTD PMID:32234424 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Pltp phospholipid transfer protein decreases expression EXP lasiocarpine results in decreased expression of PLTP mRNA CTD PMID:32419051 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit increases expression ISO lasiocarpine results in increased expression of POLE2 mRNA CTD PMID:32234424 NCBI chr 6:91,494,348...91,532,355
Ensembl chr 6:91,494,393...91,518,996
JBrowse link
G Polq DNA polymerase theta increases expression ISO lasiocarpine results in increased expression of POLQ mRNA CTD PMID:32234424 NCBI chr11:66,585,860...66,695,369
Ensembl chr11:66,585,881...66,695,353
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO lasiocarpine results in decreased expression of PPP2R2B mRNA CTD PMID:32234424 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases expression ISO lasiocarpine results in decreased expression of PRKN mRNA CTD PMID:32234424 NCBI chr 1:48,880,015...50,069,998 JBrowse link
G Psmc3ip PSMC3 interacting protein increases expression ISO lasiocarpine results in increased expression of PSMC3IP mRNA CTD PMID:32234424 NCBI chr10:89,002,109...89,006,075
Ensembl chr10:89,002,116...89,005,213
JBrowse link
G Ptgis prostaglandin I2 synthase decreases expression ISO lasiocarpine metabolite results in decreased expression of PTGIS mRNA; lasiocarpine metabolite results in decreased expression of PTGIS protein CTD PMID:30465738 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO lasiocarpine metabolite results in increased expression of PTGS2 mRNA; lasiocarpine metabolite results in increased expression of PTGS2 protein CTD PMID:30465738 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rad51b RAD51 paralog B decreases expression ISO lasiocarpine results in decreased expression of RAD51B mRNA CTD PMID:32234424 NCBI chr 6:102,473,978...103,018,185
Ensembl chr 6:102,477,036...102,512,505
JBrowse link
G Rdh16 retinol dehydrogenase 16 decreases expression ISO lasiocarpine results in decreased expression of RDH16 mRNA CTD PMID:32234424 NCBI chr 7:71,058,150...71,072,685
Ensembl chr 7:70,980,422...71,072,689
JBrowse link
G RGD1307443 similar to mKIAA0319 protein increases expression ISO lasiocarpine results in increased expression of KIAA0319 mRNA CTD PMID:32234424 NCBI chr17:42,163,245...42,226,725
Ensembl chr17:42,165,817...42,226,377
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO lasiocarpine results in increased expression of RGS16 mRNA CTD PMID:32234424 NCBI chr13:71,163,411...71,185,147
Ensembl chr13:71,179,910...71,185,216
JBrowse link
G Rhbdl3 rhomboid like 3 increases expression ISO lasiocarpine results in increased expression of RHBDL3 mRNA CTD PMID:32234424 NCBI chr10:67,676,999...67,731,670
Ensembl chr10:67,677,071...67,731,670
JBrowse link
G Rhbg Rh family B glycoprotein decreases expression ISO lasiocarpine results in decreased expression of RHBG mRNA CTD PMID:32234424 NCBI chr 2:187,610,081...187,622,408
Ensembl chr 2:187,610,087...187,622,373
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO lasiocarpine results in increased expression of RRAD mRNA CTD PMID:32234424 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G Sbk1 SH3 domain binding kinase 1 increases expression ISO lasiocarpine results in increased expression of SBK1 mRNA CTD PMID:32234424 NCBI chr 1:197,636,230...197,681,031
Ensembl chr 1:67,368,384...67,390,141
Ensembl chr 1:67,368,384...67,390,141
JBrowse link
G Sdk1 sidekick cell adhesion molecule 1 decreases expression ISO lasiocarpine results in decreased expression of SDK1 mRNA CTD PMID:32234424 NCBI chr12:14,445,798...15,443,442
Ensembl chr12:14,449,010...15,098,786
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO lasiocarpine results in increased expression of SERPINB2 mRNA CTD PMID:32234424 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Sfn stratifin increases expression ISO lasiocarpine results in increased expression of SFN mRNA CTD PMID:32234424 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 decreases expression ISO lasiocarpine results in decreased expression of SH3RF3 mRNA CTD PMID:32234424 NCBI chr20:28,355,671...28,720,020
Ensembl chr20:28,572,242...28,717,243
JBrowse link
G Slc27a5 solute carrier family 27 member 5 decreases expression ISO lasiocarpine results in decreased expression of SLC27A5 mRNA CTD PMID:32234424 NCBI chr 1:65,576,599...65,587,192
Ensembl chr 1:65,576,535...65,587,186
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 decreases expression ISO lasiocarpine results in decreased expression of SMPD3 mRNA CTD PMID:32234424 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Sparcl1 SPARC like 1 decreases expression ISO lasiocarpine results in decreased expression of SPARCL1 mRNA CTD PMID:32234424 NCBI chr14:6,994,261...7,025,309
Ensembl chr14:6,994,190...7,025,308
JBrowse link
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 decreases expression ISO lasiocarpine results in decreased expression of SPOCK3 mRNA CTD PMID:32234424 NCBI chr16:28,372,067...28,716,762
Ensembl chr16:28,372,411...28,716,885
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases expression ISO lasiocarpine results in increased expression of SRC mRNA CTD PMID:32234424 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP lasiocarpine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Stk31 serine threonine kinase 31 decreases expression ISO lasiocarpine results in decreased expression of STK31 mRNA CTD PMID:32234424 NCBI chr 4:79,055,493...79,153,849
Ensembl chr 4:79,055,280...79,153,831
JBrowse link
G Sucnr1 succinate receptor 1 decreases expression ISO lasiocarpine results in decreased expression of SUCNR1 mRNA CTD PMID:32234424 NCBI chr 2:150,211,897...150,212,848
Ensembl chr 2:150,211,898...150,212,848
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase decreases expression ISO lasiocarpine results in decreased expression of SUGCT mRNA CTD PMID:32234424 NCBI chr17:49,991,314...51,030,950 JBrowse link
G Tcf19 transcription factor 19 increases expression ISO lasiocarpine results in increased expression of TCF19 mRNA CTD PMID:32234424 NCBI chr20:3,740,454...3,746,964
Ensembl chr20:3,744,395...3,746,964
JBrowse link
G Tek TEK receptor tyrosine kinase decreases expression ISO lasiocarpine metabolite results in decreased expression of TEK mRNA CTD PMID:30465738 NCBI chr 5:113,725,717...113,852,799
Ensembl chr 5:113,725,717...113,852,799
JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated increases expression ISO lasiocarpine results in increased expression of TEX15 mRNA CTD PMID:32234424 NCBI chr16:62,313,284...62,373,288
Ensembl chr16:62,313,263...62,373,253
JBrowse link
G Tfpi tissue factor pathway inhibitor decreases expression ISO lasiocarpine metabolite results in decreased expression of TFPI mRNA CTD PMID:30465738 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of TGFB1 mRNA CTD PMID:30465738 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO lasiocarpine results in decreased expression of THRSP mRNA CTD PMID:32234424 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Tmem266 transmembrane protein 266 decreases expression ISO lasiocarpine results in decreased expression of TMEM266 mRNA CTD PMID:32234424 NCBI chr 8:59,952,732...60,014,363
Ensembl chr 8:59,900,651...60,014,363
JBrowse link
G Tmsb15b2 thymosin beta 15B2 increases expression ISO lasiocarpine results in increased expression of TMSB15A mRNA CTD PMID:32234424 NCBI chr  X:107,612,518...107,614,632
Ensembl chr  X:107,612,518...107,614,632
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO lasiocarpine metabolite results in decreased expression of TNFSF10 mRNA CTD PMID:30465738 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp73 tumor protein p73 increases expression ISO lasiocarpine results in increased expression of TP73 mRNA CTD PMID:32234424 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression ISO lasiocarpine results in increased expression of TRIP13 mRNA CTD PMID:32234424 NCBI chr 1:31,967,980...32,012,923
Ensembl chr 1:31,967,978...32,012,919
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases expression ISO lasiocarpine results in increased expression of TRPA1 mRNA CTD PMID:32234424 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Tspan15 tetraspanin 15 increases expression ISO lasiocarpine results in increased expression of TSPAN15 mRNA CTD PMID:32234424 NCBI chr20:31,812,558...31,857,191
Ensembl chr20:31,813,192...31,857,097
JBrowse link
G Tymp thymidine phosphorylase increases expression ISO lasiocarpine metabolite results in increased expression of TYMP mRNA CTD PMID:30465738 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO lasiocarpine results in decreased expression of TYRP1 mRNA CTD PMID:32234424 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP lasiocarpine results in increased expression of UGT2B17 mRNA CTD PMID:32419051 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 increases expression ISO lasiocarpine results in increased expression of UHRF1 mRNA CTD PMID:32234424 NCBI chr 9:10,738,211...10,758,403
Ensembl chr 9:10,738,222...10,757,954
JBrowse link
G Vwf von Willebrand factor decreases expression ISO lasiocarpine metabolite results in decreased expression of VWF mRNA CTD PMID:30465738 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wnt7b Wnt family member 7B increases expression ISO lasiocarpine results in increased expression of WNT7B mRNA CTD PMID:32234424 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723
JBrowse link
G Wwox WW domain-containing oxidoreductase decreases expression ISO lasiocarpine results in decreased expression of WWOX mRNA CTD PMID:32234424 NCBI chr19:46,761,353...47,695,247 JBrowse link
riddelliine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP riddelliine results in increased expression of ABCB1 mRNA; riddelliine results in increased expression of ABCB1A mRNA CTD PMID:18047722, PMID:18047727 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 decreases expression EXP riddelliine results in decreased expression of ABCB9 mRNA CTD PMID:18047722 NCBI chr12:37,923,974...37,956,678
Ensembl chr12:37,923,528...37,958,363
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP riddelliine results in increased expression of ABCC3 mRNA CTD PMID:18047722, PMID:18047727 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 decreases expression EXP riddelliine results in decreased expression of ABCC8 mRNA CTD PMID:18047722, PMID:18047727 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression EXP riddelliine results in decreased expression of ABCC9 mRNA CTD PMID:18047727 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Adm adrenomedullin decreases expression EXP riddelliine results in decreased expression of ADM mRNA CTD PMID:18047727 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression EXP riddelliine results in increased expression of AHR mRNA CTD PMID:18047727 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Atp13a5 ATPase 13A5 decreases expression EXP riddelliine results in decreased expression of ATP13A5 mRNA CTD PMID:18047722 NCBI chr11:74,984,538...75,124,249
Ensembl chr11:74,984,613...75,124,249
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP riddelliine results in increased expression of CES2 mRNA CTD PMID:18047722 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression EXP riddelliine results in increased expression of CXCR1 mRNA CTD PMID:18047727 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression EXP riddelliine results in increased expression of CYP26A1 mRNA CTD PMID:18047727 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP riddelliine results in decreased expression of CYP2C mRNA CTD PMID:18047722, PMID:18047727 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 increases expression EXP riddelliine results in increased expression of CYP2C12 mRNA CTD PMID:18047727 NCBI chr 1:258,709,726...258,766,873
Ensembl chr 1:258,709,721...258,766,881
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP riddelliine results in decreased expression of CYP2C13 mRNA CTD PMID:18047727 NCBI chr 1:258,796,624...258,877,023
Ensembl chr 1:258,796,622...258,877,045
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 decreases expression EXP riddelliine results in decreased expression of CYP2C22 mRNA CTD PMID:18047727 NCBI chr 1:259,257,658...259,297,270
Ensembl chr 1:259,257,657...259,287,684
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP riddelliine results in increased expression of CYP2E1 mRNA CTD PMID:18047722, PMID:18047727 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 decreases expression EXP riddelliine results in decreased expression of CYP3A18 mRNA CTD PMID:18047727 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression EXP riddelliine results in decreased expression of CYP3A2 mRNA CTD PMID:18047727 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression EXP riddelliine results in increased expression of CYP3A9 mRNA CTD PMID:18047727 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 decreases expression EXP riddelliine results in decreased expression of CYP4A8 mRNA CTD PMID:18047727 NCBI chr 5:133,978,953...134,008,255
Ensembl chr 5:133,978,954...134,008,255
JBrowse link
G Egr1 early growth response 1 increases expression EXP riddelliine results in increased expression of EGR1 mRNA CTD PMID:18047727 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP riddelliine results in decreased expression of ENPP2 mRNA CTD PMID:18047727 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G F11r F11 receptor decreases expression EXP riddelliine results in decreased expression of F11R mRNA CTD PMID:18047727 NCBI chr13:89,826,272...89,850,151
Ensembl chr13:89,826,254...89,850,612
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression EXP riddelliine results in decreased expression of F3 mRNA CTD PMID:18047727 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G F7 coagulation factor VII increases expression EXP riddelliine results in increased expression of F7 mRNA CTD PMID:18047727 NCBI chr16:81,824,610...81,834,923
Ensembl chr16:81,824,111...81,834,945
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP riddelliine results in increased expression of FAS mRNA CTD PMID:18047727 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 increases expression EXP riddelliine results in increased expression of FMO5 mRNA CTD PMID:18047722 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP riddelliine results in increased expression of GSTA3 mRNA CTD PMID:18047722, PMID:18047727 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP riddelliine results in decreased expression of GSTM1 mRNA CTD PMID:18047727 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP riddelliine results in decreased expression of GSTM2 mRNA CTD PMID:18047727 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Hgf hepatocyte growth factor increases expression EXP riddelliine results in increased expression of HGF mRNA CTD PMID:18047727 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP riddelliine results in increased expression of IGFBP1 mRNA CTD PMID:18047727 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression EXP riddelliine results in increased expression of IGFBP2 mRNA CTD PMID:18047727 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Il11 interleukin 11 increases expression EXP riddelliine results in increased expression of IL11 mRNA CTD PMID:18047727 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il15 interleukin 15 increases expression EXP riddelliine results in increased expression of IL15 mRNA CTD PMID:18047727 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
JBrowse link
G Il7 interleukin 7 decreases expression EXP riddelliine results in decreased expression of IL7 mRNA CTD PMID:18047727 NCBI chr 2:96,427,884...96,474,979
Ensembl chr 2:96,439,286...96,474,977
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP riddelliine results in decreased expression of INMT mRNA CTD PMID:18047722 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Itga4 integrin subunit alpha 4 increases expression EXP riddelliine results in increased expression of ITGA4 mRNA CTD PMID:18047727 NCBI chr 3:66,178,745...66,265,547
Ensembl chr 3:66,193,059...66,263,960
JBrowse link
G Itga6 integrin subunit alpha 6 decreases expression EXP riddelliine results in decreased expression of ITGA6 mRNA CTD PMID:18047727 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Kdr kinase insert domain receptor multiple interactions
increases expression
EXP riddelliine results in increased phosphorylation of and results in increased activity of KDR protein
riddelliine results in increased expression of KDR protein
CTD PMID:12460743, PMID:15384251 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases mutagenesis ISO riddelliine results in increased mutagenesis of KRAS gene CTD PMID:13678655, PMID:20737008 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Lepr leptin receptor increases expression EXP riddelliine results in increased expression of LEPR mRNA CTD PMID:18047727 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression EXP riddelliine results in decreased expression of MMP7 mRNA CTD PMID:18047727 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mt1 metallothionein 1 increases expression EXP riddelliine results in increased expression of MT1A mRNA CTD PMID:18047727 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression EXP riddelliine results in decreased expression of MTHFD2 mRNA CTD PMID:18047727 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP riddelliine results in increased expression of NQO1 mRNA CTD PMID:18047722, PMID:18047727 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression EXP riddelliine results in decreased expression of PPARG mRNA CTD PMID:18047727 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Prkca protein kinase C, alpha increases expression EXP riddelliine results in increased expression of PRKCA mRNA CTD PMID:18047727 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP riddelliine results in increased expression of PRKCZ mRNA CTD PMID:18047727 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Ren renin increases expression EXP riddelliine results in increased expression of REN mRNA CTD PMID:18047727 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 decreases expression EXP riddelliine results in decreased expression of S1PR2 mRNA CTD PMID:18047727 NCBI chr 8:21,984,914...21,995,806
Ensembl chr 8:21,984,914...21,995,806
JBrowse link
G Slc13a5 solute carrier family 13 member 5 decreases expression EXP riddelliine results in decreased expression of SLC13A5 mRNA CTD PMID:18047722 NCBI chr10:58,806,581...58,835,549
Ensembl chr10:58,810,058...58,834,538
JBrowse link
G Slc16a4 solute carrier family 16, member 4 decreases expression EXP riddelliine results in decreased expression of SLC16A4 mRNA CTD PMID:18047722 NCBI chr 2:210,045,122...210,161,017
Ensembl chr 2:210,045,161...210,068,502
JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases expression EXP riddelliine results in decreased expression of SLC22A6 mRNA CTD PMID:18047722 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases expression EXP riddelliine results in decreased expression of SLC22A8 mRNA CTD PMID:18047722 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc25a21 solute carrier family 25 member 21 increases expression EXP riddelliine results in increased expression of SLC25A21 mRNA CTD PMID:18047722 NCBI chr 6:77,624,384...78,121,339
Ensembl chr 6:77,624,385...77,848,434
JBrowse link
G Slc25a30 solute carrier family 25, member 30 decreases expression EXP riddelliine results in decreased expression of SLC25A30 mRNA CTD PMID:18047722 NCBI chr15:57,811,612...57,834,173
Ensembl chr15:57,813,356...57,834,173
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression EXP riddelliine results in increased expression of SLC7A5 mRNA CTD PMID:18047727 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases expression EXP riddelliine results in increased expression of SRC mRNA CTD PMID:18047727 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 decreases expression EXP riddelliine results in decreased expression of SULT1C1 mRNA CTD PMID:18047722 NCBI chr 9:4,931,038...4,978,847
Ensembl chr 9:4,930,818...4,978,892
JBrowse link
G Tgfa transforming growth factor alpha decreases expression EXP riddelliine results in decreased expression of TGFA mRNA CTD PMID:18047727 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tnf tumor necrosis factor decreases expression EXP riddelliine results in decreased expression of TNF mRNA CTD PMID:18047727 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression EXP riddelliine results in increased expression of TNFSF10 mRNA CTD PMID:18047727 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tp53 tumor protein p53 increases expression
increases mutagenesis
EXP
ISO
riddelliine results in increased expression of TP53 protein
riddelliine results in increased mutagenesis of TRP53 gene
CTD PMID:12460743, PMID:13678655, PMID:20737008 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
senecionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO senecionine results in decreased expression of ABCB11 mRNA CTD PMID:26100227, PMID:31606820 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO senecionine results in decreased expression of ABCB1 mRNA CTD PMID:31606820 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP senecionine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO senecionine results in decreased expression of ABCB4 mRNA CTD PMID:31606820 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO senecionine results in increased expression of ABCC1 mRNA CTD PMID:31606820 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO senecionine results in decreased expression of ABCC2 mRNA CTD PMID:26100227, PMID:31606820 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
EXP
ISO
senecionine results in increased expression of ABCC3 mRNA
senecionine results in decreased expression of ABCC3 mRNA
CTD PMID:24641316, PMID:26100227, PMID:31606820 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO senecionine results in decreased expression of ABCC4 mRNA CTD PMID:31606820 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO senecionine results in decreased expression of ABCC6 mRNA CTD PMID:26100227 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO senecionine results in decreased expression of ACSL3 mRNA CTD PMID:26100227 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO senecionine results in decreased expression of ACSM3 mRNA CTD PMID:26100227 NCBI chr 1:189,514,504...189,541,233
Ensembl chr 1:189,514,553...189,541,224
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP senecionine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:212,317,510...212,332,895
Ensembl chr 1:212,317,848...212,330,349
JBrowse link
G Aff3 AF4/FMR2 family, member 3 decreases expression ISO senecionine results in decreased expression of AFF3 mRNA CTD PMID:26100227 NCBI chr 9:44,837,979...45,291,964
Ensembl chr 9:44,839,960...45,292,047
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression ISO senecionine results in decreased expression of AGXT mRNA CTD PMID:26100227 NCBI chr 9:100,281,339...100,291,292
Ensembl chr 9:100,281,339...100,291,291
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP senecionine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO senecionine results in increased expression of ALDH6A1 mRNA CTD PMID:26100227 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO senecionine results in decreased expression of ALDH8A1 mRNA CTD PMID:26100227 NCBI chr 1:16,910,043...16,929,465
Ensembl chr 1:16,910,069...16,930,481
JBrowse link
G Areg amphiregulin increases expression ISO senecionine results in increased expression of AREG mRNA CTD PMID:26100227 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A increases expression EXP senecionine results in increased expression of ARHGAP11A mRNA CTD PMID:32419051 NCBI chr 3:105,281,827...105,298,108
Ensembl chr 3:105,281,827...105,298,108
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression EXP senecionine results in increased expression of ATAD2 mRNA CTD PMID:32419051 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Axin2 axin 2 decreases expression ISO senecionine results in decreased expression of AXIN2 mRNA CTD PMID:31606820 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression EXP
ISO
senecionine results in decreased expression of BAAT mRNA CTD PMID:24641316, PMID:26100227 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO senecionine results in decreased expression of BCL2L1 protein CTD PMID:29458164 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Casp12 caspase 12 increases expression EXP senecionine results in increased expression of CASP12 mRNA CTD PMID:32419051 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions ISO senecionine results in increased activity of and results in increased cleavage of CASP3 protein CTD PMID:29458164 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO senecionine results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:29458164 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases activity ISO senecionine results in increased activity of CASP9 protein CTD PMID:29458164 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccna2 cyclin A2 increases expression EXP senecionine results in increased expression of CCNA2 mRNA CTD PMID:32419051 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccne2 cyclin E2 increases expression EXP senecionine results in increased expression of CCNE2 mRNA CTD PMID:32419051 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng1 cyclin G1 increases expression EXP senecionine results in increased expression of CCNG1 mRNA CTD PMID:32419051 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP senecionine results in increased expression of CDKN1A mRNA CTD PMID:32419051 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cenpq centromere protein Q increases expression EXP senecionine results in increased expression of CENPQ mRNA CTD PMID:32419051 NCBI chr 9:23,352,271...23,368,774 JBrowse link
G Cenpw centromere protein W increases expression EXP senecionine results in increased expression of CENPW mRNA CTD PMID:32419051 NCBI chr 1:29,915,443...29,920,598
Ensembl chr 1:29,915,443...29,920,598
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression EXP senecionine results in increased expression of CKAP2 mRNA CTD PMID:32419051 NCBI chr16:74,752,655...74,779,184
Ensembl chr16:74,752,655...74,779,184
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP senecionine results in decreased expression of CLEC4F mRNA CTD PMID:32419051 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP senecionine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP11A1 mRNA CTD PMID:26100227 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP1A1 mRNA CTD PMID:26100227 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
decreases expression
ISO senecionine results in increased expression of CYP1A2 mRNA
senecionine results in decreased expression of CYP1A2 mRNA
CTD PMID:26100227, PMID:31606820 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP1B1 mRNA CTD PMID:26100227 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 affects expression ISO senecionine affects the expression of CYP2B10 mRNA CTD PMID:31606820 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO senecionine results in increased expression of CYP2B6 mRNA CTD PMID:26100227 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 decreases expression ISO senecionine results in decreased expression of CYP2C18 mRNA CTD PMID:26100227 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
decreases expression
ISO senecionine results in increased expression of CYP2E1 mRNA
senecionine results in decreased expression of CYP2E1 mRNA
CTD PMID:26100227, PMID:31606820 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression ISO senecionine results in increased expression of CYP3A43 mRNA CTD PMID:26100227 NCBI chr12:10,636,294...10,684,273
Ensembl chr12:10,636,275...10,684,278
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO senecionine results in decreased expression of CYP3A5 mRNA CTD PMID:26100227 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO senecionine results in decreased expression of CYP4F12 mRNA CTD PMID:26100227 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP
ISO
senecionine results in decreased expression of CYP7A1 mRNA CTD PMID:24641316, PMID:26100227, PMID:31606820 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO senecionine results in decreased expression of CYP8B1 mRNA CTD PMID:26100227 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases expression EXP senecionine results in increased expression of CYRIA mRNA CTD PMID:32419051 NCBI chr 6:37,555,167...37,661,196
Ensembl chr 6:37,555,182...37,665,064
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor increases expression EXP senecionine results in increased expression of DDIAS mRNA CTD PMID:32419051 NCBI chr 1:157,675,754...157,700,064
Ensembl chr 1:157,675,765...157,700,064
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO senecionine results in increased expression of DHRS2 mRNA CTD PMID:26100227 NCBI chr15:33,876,701...33,891,559
Ensembl chr15:33,885,106...33,891,539
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression ISO senecionine results in increased expression of DHRS9 mRNA CTD PMID:26100227 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325
JBrowse link
G Diaph3 diaphanous-related formin 3 increases expression EXP senecionine results in increased expression of DIAPH3 mRNA CTD PMID:32419051 NCBI chr15:69,928,507...70,400,077
Ensembl chr15:70,039,424...70,399,924
JBrowse link
G Dlgap5 DLG associated protein 5 increases expression EXP senecionine results in increased expression of DLGAP5 mRNA CTD PMID:32419051 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression ISO senecionine results in decreased expression of DPYD mRNA CTD PMID:26100227 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog increases expression EXP senecionine results in increased expression of DTL mRNA CTD PMID:32419051 NCBI chr13:110,219,276...110,257,345
Ensembl chr13:110,220,283...110,257,367
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression EXP senecionine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:66,560,200...66,602,509
Ensembl chr  X:66,561,286...66,602,506
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO senecionine results in decreased expression of EPHX2 mRNA CTD PMID:26100227 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 increases expression EXP senecionine results in increased expression of ESCO2 mRNA CTD PMID:32419051 NCBI chr15:42,500,929...42,519,019
Ensembl chr15:42,500,929...42,518,855
JBrowse link
G Ethe1 ETHE1, persulfide dioxygenase decreases expression EXP senecionine results in decreased expression of ETHE1 mRNA CTD PMID:32419051 NCBI chr 1:81,457,008...81,472,061
Ensembl chr 1:81,456,984...81,472,097
JBrowse link
G Fancd2 FA complementation group D2 increases expression EXP senecionine results in increased expression of FANCD2 mRNA CTD PMID:32419051 NCBI chr 4:145,489,869...145,551,479
Ensembl chr 4:145,489,869...145,551,479
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO
EXP
senecionine metabolite results in increased expression of FAS mRNA
senecionine results in increased expression of FAS mRNA
CTD PMID:30465738, PMID:32419051 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 decreases expression ISO senecionine results in decreased expression of FMO4 mRNA CTD PMID:26100227 NCBI chr13:80,685,385...80,703,575
Ensembl chr13:80,685,325...80,703,615
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 decreases expression ISO senecionine results in decreased expression of FMO5 mRNA CTD PMID:26100227 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO senecionine results in increased expression of GEM mRNA CTD PMID:26100227 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gls glutaminase increases expression ISO senecionine results in increased expression of GLS mRNA CTD PMID:26100227 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Glyat glycine-N-acyltransferase decreases expression ISO senecionine results in decreased expression of GLYAT mRNA CTD PMID:26100227 NCBI chr 1:229,060,125...229,081,113
Ensembl chr 1:229,063,714...229,080,410
JBrowse link
G Gnmt glycine N-methyltransferase increases expression ISO senecionine results in increased expression of GNMT mRNA CTD PMID:26100227 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Gphn gephyrin decreases expression ISO senecionine results in decreased expression of GPHN mRNA CTD PMID:26100227 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A increases expression ISO senecionine results in increased expression of GPRC5A mRNA CTD PMID:26100227 NCBI chr 4:168,832,937...168,851,650
Ensembl chr 4:168,832,910...168,851,652
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
increases expression
multiple interactions
EXP
ISO
senecionine results in increased activity of GPT protein
senecionine results in increased expression of GPT protein
POR protein affects the reaction [senecionine results in increased expression of GPT protein]
CTD PMID:24641316, PMID:31606820 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP senecionine results in increased expression of GRIA3 mRNA CTD PMID:32419051 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 decreases expression ISO senecionine results in decreased expression of GSTA4 mRNA CTD PMID:26100227 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstt1 glutathione S-transferase theta 1 decreases expression ISO senecionine results in decreased expression of GSTT1 mRNA CTD PMID:26100227 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gzma granzyme A decreases expression EXP senecionine results in decreased expression of GZMA mRNA CTD PMID:32419051 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 increases expression EXP senecionine results in increased expression of HERC6 mRNA CTD PMID:32419051 NCBI chr 4:88,606,851...88,649,424
Ensembl chr 4:88,607,518...88,649,216
JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression EXP senecionine results in increased expression of HMMR mRNA CTD PMID:32419051 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO senecionine results in decreased expression of HNMT mRNA CTD PMID:26100227 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression EXP senecionine results in increased expression of IFIT2 mRNA CTD PMID:32419051 NCBI chr 1:252,894,663...252,900,727
Ensembl chr 1:252,894,663...252,900,726
JBrowse link
G Il11 interleukin 11 increases expression ISO senecionine metabolite results in increased expression of IL11 mRNA CTD PMID:30465738 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il17rd interleukin 17 receptor D increases expression EXP senecionine results in increased expression of IL17RD mRNA CTD PMID:32419051 NCBI chr16:2,670,471...2,737,271
Ensembl chr16:2,670,618...2,731,808
JBrowse link
G Il1b interleukin 1 beta increases expression ISO senecionine metabolite results in increased expression of IL1B mRNA CTD PMID:30465738 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP senecionine results in decreased expression of INMT mRNA CTD PMID:32419051 NCBI chr 4:85,381,907...85,386,203
Ensembl chr 4:85,381,889...85,386,231
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression ISO senecionine results in increased expression of ISG20 mRNA CTD PMID:26100227 NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946
JBrowse link
G Jam3 junctional adhesion molecule 3 increases expression EXP senecionine results in increased expression of JAM3 mRNA CTD PMID:32419051 NCBI chr 8:28,147,110...28,208,466
Ensembl chr 8:28,147,111...28,208,466
JBrowse link
G Kif11 kinesin family member 11 increases expression EXP senecionine results in increased expression of KIF11 mRNA CTD PMID:32419051 NCBI chr 1:256,035,866...256,088,299
Ensembl chr 1:256,035,866...256,088,299
JBrowse link
G Kif18a kinesin family member 18A increases expression EXP senecionine results in increased expression of KIF18A mRNA CTD PMID:32419051 NCBI chr 3:100,366,168...100,426,867
Ensembl chr 3:100,366,168...100,427,030
JBrowse link
G Kntc1 kinetochore associated 1 increases expression EXP senecionine results in increased expression of KNTC1 mRNA CTD PMID:32419051 NCBI chr12:38,200,463...38,274,162
Ensembl chr12:38,200,463...38,274,036
JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases expression ISO senecionine results in decreased expression of KYAT1 mRNA CTD PMID:26100227 NCBI chr 3:8,752,289...8,785,617
Ensembl chr 3:8,752,625...8,766,433
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP senecionine results in increased expression of LBP mRNA CTD PMID:32419051 NCBI chr 3:154,786,232...154,812,910
Ensembl chr 3:154,786,215...154,813,464
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO senecionine results in increased expression of LCN2 mRNA CTD PMID:31606820 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lgr5 leucine rich repeat containing G protein coupled receptor 5 decreases expression ISO senecionine results in decreased expression of LGR5 mRNA CTD PMID:31606820 NCBI chr 7:58,447,097...58,587,787
Ensembl chr 7:58,448,277...58,587,787
JBrowse link
G LOC100911204 protein CASC5-like increases expression EXP senecionine results in increased expression of KNL1 mRNA CTD PMID:32419051 NCBI chr 3:112,531,429...112,560,698
Ensembl chr 3:112,531,703...112,560,634
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 increases expression EXP senecionine results in increased expression of MAD2L1 mRNA CTD PMID:32419051 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO senecionine results in increased expression of MAFF mRNA CTD PMID:26100227 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Maoa monoamine oxidase A decreases expression ISO senecionine results in decreased expression of MAOA mRNA CTD PMID:26100227 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like increases expression EXP senecionine results in increased expression of MASTL mRNA CTD PMID:32419051 NCBI chr17:89,839,562...89,875,855
Ensembl chr17:89,742,140...89,876,825
JBrowse link
G Mcm3 minichromosome maintenance complex component 3 increases expression EXP senecionine results in increased expression of MCM3 mRNA CTD PMID:32419051 NCBI chr 9:26,914,057...26,932,201
Ensembl chr 9:26,914,057...26,932,201
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 increases expression EXP senecionine results in increased expression of MCM5 mRNA CTD PMID:32419051 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP senecionine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP senecionine results in increased expression of MKI67 mRNA CTD PMID:32419051 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO senecionine results in increased expression of MMP1 mRNA CTD PMID:26100227 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mt2A metallothionein 2A increases expression ISO senecionine results in increased expression of MT2 mRNA CTD PMID:31606820 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP senecionine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 5:9,279,756...9,315,112
Ensembl chr 5:9,279,970...9,315,114
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression EXP senecionine results in increased expression of MYBL2 mRNA CTD PMID:32419051 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H increases expression EXP senecionine results in increased expression of NCAPH mRNA CTD PMID:32419051 NCBI chr 3:119,583,798...119,611,148
Ensembl chr 3:119,583,648...119,611,136
JBrowse link
G Ndc80 NDC80 kinetochore complex component increases expression EXP senecionine results in increased expression of NDC80 mRNA CTD PMID:32419051 NCBI chr 9:119,837,857...119,871,435
Ensembl chr 9:119,839,016...119,871,382
JBrowse link
G Neb nebulin decreases expression ISO senecionine results in decreased expression of NEB mRNA CTD PMID:26100227 NCBI chr 3:37,658,081...37,855,843
Ensembl chr 3:37,658,563...37,854,561
JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression ISO senecionine results in decreased expression of NNMT mRNA CTD PMID:26100227 NCBI chr 8:52,918,437...52,938,172
Ensembl chr 8:52,925,175...52,937,972
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO senecionine results in increased expression of NQO1 mRNA CTD PMID:26100227 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression EXP
ISO
senecionine results in decreased expression of NR0B2 mRNA CTD PMID:24641316, PMID:31606820 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP senecionine results in decreased expression of NR1H4 mRNA CTD PMID:24641316 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression ISO senecionine results in decreased expression of NR1I3 mRNA CTD PMID:31606820 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP senecionine results in decreased expression of NR3C1 mRNA CTD PMID:32419051 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression EXP senecionine results in increased expression of NRCAM mRNA CTD PMID:32419051 NCBI chr 6:64,297,843...64,867,408
Ensembl chr 6:64,297,888...64,864,996
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP senecionine results in increased expression of NRG1 mRNA CTD PMID:32419051 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 increases expression EXP senecionine results in increased expression of NUSAP1 mRNA CTD PMID:32419051 NCBI chr 3:111,422,267...111,452,600
Ensembl chr 3:111,422,267...111,452,971
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO senecionine results in decreased expression of PARP1 protein CTD PMID:29458164 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pclaf PCNA clamp associated factor increases expression EXP senecionine results in increased expression of PCLAF mRNA CTD PMID:32419051 NCBI chr 8:71,514,281...71,526,182
Ensembl chr 8:71,514,281...71,526,182
JBrowse link
G Plk4 polo-like kinase 4 increases expression EXP senecionine results in increased expression of PLK4 mRNA CTD PMID:32419051 NCBI chr 2:127,686,911...127,705,518
Ensembl chr 2:127,686,925...127,705,518
JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions
affects response to substance
ISO POR protein affects the reaction [senecionine results in increased expression of GPT protein]
POR protein affects the susceptibility to senecionine
CTD PMID:31606820 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression EXP senecionine results in increased expression of PRC1 mRNA CTD PMID:32419051 NCBI chr 1:142,087,181...142,108,746
Ensembl chr 1:142,087,208...142,108,746
JBrowse link
G Ptgis prostaglandin I2 synthase decreases expression ISO senecionine metabolite results in decreased expression of PTGIS mRNA; senecionine metabolite results in decreased expression of PTGIS protein CTD PMID:30465738 NCBI chr 3:163,950,746...163,986,129 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO senecionine metabolite results in increased expression of PTGS2 mRNA; senecionine metabolite results in increased expression of PTGS2 protein CTD PMID:30465738 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression ISO senecionine results in decreased expression of PTPRD mRNA CTD PMID:26100227 NCBI chr 5:92,862,229...93,514,071
Ensembl chr 5:92,862,267...93,244,202
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO senecionine results in decreased expression of RAPGEF4 mRNA CTD PMID:26100227 NCBI chr 3:58,632,338...58,925,127
Ensembl chr 3:58,632,476...58,924,038
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO senecionine results in increased expression of RRAD mRNA CTD PMID:26100227 NCBI chr19:561,696...564,929
Ensembl chr19:561,727...564,930
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 increases expression EXP senecionine results in increased expression of RRM1 mRNA CTD PMID:32419051 NCBI chr 1:167,538,387...167,562,688
Ensembl chr 1:167,538,263...167,562,688
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO senecionine results in increased expression of SAT1 mRNA CTD PMID:26100227 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sgcb sarcoglycan, beta increases expression EXP senecionine results in increased expression of SGCB mRNA CTD PMID:32419051 NCBI chr14:37,113,194...37,128,623
Ensembl chr14:37,113,210...37,128,737
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP
ISO
senecionine results in decreased expression of SLC10A1 mRNA CTD PMID:24641316, PMID:31606820 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc22a1 solute carrier family 22 member 1 decreases expression ISO senecionine results in decreased expression of SLC22A1 mRNA CTD PMID:31606820 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a25 solute carrier family 22, member 25 decreases expression ISO senecionine results in decreased expression of SLC22A9 mRNA CTD PMID:26100227 NCBI chr 1:224,596,886...224,698,512
Ensembl chr 1:224,596,887...224,698,514
JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression ISO senecionine results in decreased expression of SLC22A7 mRNA CTD PMID:26100227, PMID:31606820 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 decreases expression EXP senecionine results in decreased expression of SLCO1A2 mRNA CTD PMID:24641316 NCBI chr 4:175,969,549...176,026,227
Ensembl chr 4:175,969,549...176,026,163
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression EXP
ISO
senecionine results in decreased expression of SLCO1B2 mRNA
senecionine results in decreased expression of SLCO1B3 mRNA
CTD PMID:24641316, PMID:26100227, PMID:31606820 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Smc2 structural maintenance of chromosomes 2 increases expression EXP senecionine results in increased expression of SMC2 mRNA CTD PMID:32419051 NCBI chr 5:68,717,509...68,764,080
Ensembl chr 5:68,717,519...68,763,850
JBrowse link
G Smc4 structural maintenance of chromosomes 4 increases expression EXP senecionine results in increased expression of SMC4 mRNA CTD PMID:32419051 NCBI chr 2:165,600,934...165,629,415
Ensembl chr 2:165,601,007...165,629,415
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP senecionine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr 7:70,807,427...70,815,271
Ensembl chr 7:70,807,867...70,815,270
JBrowse link
G Stil STIL, centriolar assembly protein increases expression EXP senecionine results in increased expression of STIL mRNA CTD PMID:32419051 NCBI chr 5:133,819,302...133,851,362
Ensembl chr 5:133,819,726...133,851,416
JBrowse link
G Stmn1 stathmin 1 increases expression EXP senecionine results in increased expression of STMN1 mRNA CTD PMID:32419051 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases expression ISO senecionine results in decreased expression of SULT1E1 mRNA CTD PMID:26100227 NCBI chr14:22,070,861...22,089,264
Ensembl chr14:22,072,024...22,089,248
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression ISO senecionine results in decreased expression of SULT2A1 mRNA CTD PMID:31606820 NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
JBrowse link
G Tcf19 transcription factor 19 increases expression EXP senecionine results in increased expression of TCF19 mRNA CTD PMID:32419051 NCBI chr20:3,740,454...3,746,964
Ensembl chr20:3,744,395...3,746,964
JBrowse link
G Tenm1 teneurin transmembrane protein 1 decreases expression ISO senecionine results in decreased expression of TENM1 mRNA CTD PMID:26100227 NCBI chr  X:129,034,755...129,336,023
NCBI chr  X:128,923,951...128,951,520
JBrowse link
G Tenm2 teneurin transmembrane protein 2 decreases expression ISO senecionine results in decreased expression of TENM2 mRNA CTD PMID:26100227 NCBI chr10:20,846,091...21,791,771
Ensembl chr10:20,844,899...21,265,026
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP senecionine results in increased expression of TOP2A mRNA CTD PMID:32419051 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Tpmt thiopurine S-methyltransferase increases expression ISO senecionine results in increased expression of TPMT mRNA CTD PMID:26100227 NCBI chr17:18,029,090...18,047,716
Ensembl chr17:18,029,124...18,047,714
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor increases expression EXP senecionine results in increased expression of TPX2 mRNA CTD PMID:32419051 NCBI chr 3:148,327,965...148,370,187
Ensembl chr 3:148,327,965...148,370,187
JBrowse link
G Ttk Ttk protein kinase increases expression EXP senecionine results in increased expression of TTK mRNA CTD PMID:32419051 NCBI chr 8:91,368,065...91,405,995
Ensembl chr 8:91,368,111...91,405,993
JBrowse link
G Tyms thymidylate synthetase increases expression EXP senecionine results in increased expression of TYMS mRNA CTD PMID:32419051 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Uchl3 ubiquitin C-terminal hydrolase L3 increases expression ISO senecionine results in increased expression of UCHL3 mRNA CTD PMID:26100227 NCBI chr15:86,153,624...86,198,127
Ensembl chr15:86,153,628...86,198,127
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glycosylation
multiple interactions
ISO UGT1A4 protein results in increased glycosylation of senecionine
[hecogenin results in decreased activity of UGT1A4 protein] which results in decreased glycosylation of senecionine
CTD PMID:20092275 NCBI chr 9:95,256,628...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 decreases expression ISO senecionine results in decreased expression of UGT2A3 mRNA CTD PMID:26100227 NCBI chr14:22,251,507...22,267,899
Ensembl chr14:22,192,970...22,619,968
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases expression ISO senecionine results in decreased expression of UGT2B1 mRNA CTD PMID:31606820 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vps13b vacuolar protein sorting 13 homolog B decreases expression ISO senecionine results in decreased expression of VPS13B mRNA CTD PMID:26100227 NCBI chr 7:74,118,834...74,722,341 JBrowse link
G Zfp367 zinc finger protein 367 increases expression EXP senecionine results in increased expression of ZFP367 mRNA CTD PMID:32419051 NCBI chr17:1,652,892...1,672,021
Ensembl chr17:1,652,895...1,672,021
JBrowse link
G Zwilch zwilch kinetochore protein increases expression EXP senecionine results in increased expression of ZWILCH mRNA CTD PMID:32419051 NCBI chr 8:69,089,449...69,121,420
Ensembl chr 8:69,091,955...69,121,192
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      atom 19808
        nonmetal atom 19683
          nitrogen atom 18565
            nitrogen molecular entity 18565
              organonitrogen compound 18335
                organonitrogen heterocyclic compound 17481
                  pyrrolizines 383
                    1-(2,3-dihydro-1H-pyrrolizin-5-yl)-2-propen-1-one 0
                    2-hydroxy-2-[(1R)-1-methoxyethyl]-3-methylbutanoic acid [(7S,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl ester 0
                    5-Acetyl-2,3-dihydro-1H-pyrrolizine 0
                    5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid + 19
                    Acetylintermedine 0
                    Acetyllycopsamine 0
                    Alexine 0
                    Angularine 0
                    Australine 0
                    Crotanecine 0
                    Echimidine 20
                    Europine 0
                    Fulvine 0
                    Heliotridine 0
                    Heliotrine 82
                    Isolycopsamine 0
                    LSM-36888 0
                    Lasiocarpine 181
                    Lycopsamine 0
                    Macrophylline 0
                    O-7-Angelylheliotridine 0
                    Phalaenopsine T 0
                    Retronecine 0
                    Rinderine 0
                    Sarracine 0
                    Senaetnine 0
                    Supinidine 0
                    Supinine 0
                    Symlandine 0
                    Trachelanthamidine 0
                    Tussilagine 0
                    Uplandicine 0
                    amabiline 0
                    indicine 0
                    intermedine 0
                    pyrrolizine + 0
                    pyrrolizine alkaloid + 213
                    symphytine + 0
                    symphytine oxide 0
                    triangularine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      p-block molecular entity 19696
                        carbon group molecular entity 19599
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                organic heterocyclic compound 18425
                                  organic heteropolycyclic compound 17838
                                    organic heterobicyclic compound 16763
                                      pyrrolizines 383
                                        1-(2,3-dihydro-1H-pyrrolizin-5-yl)-2-propen-1-one 0
                                        2-hydroxy-2-[(1R)-1-methoxyethyl]-3-methylbutanoic acid [(7S,8R)-7-hydroxy-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methyl ester 0
                                        5-Acetyl-2,3-dihydro-1H-pyrrolizine 0
                                        5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid + 19
                                        Acetylintermedine 0
                                        Acetyllycopsamine 0
                                        Alexine 0
                                        Angularine 0
                                        Australine 0
                                        Crotanecine 0
                                        Echimidine 20
                                        Europine 0
                                        Fulvine 0
                                        Heliotridine 0
                                        Heliotrine 82
                                        Isolycopsamine 0
                                        LSM-36888 0
                                        Lasiocarpine 181
                                        Lycopsamine 0
                                        Macrophylline 0
                                        O-7-Angelylheliotridine 0
                                        Phalaenopsine T 0
                                        Retronecine 0
                                        Rinderine 0
                                        Sarracine 0
                                        Senaetnine 0
                                        Supinidine 0
                                        Supinine 0
                                        Symlandine 0
                                        Trachelanthamidine 0
                                        Tussilagine 0
                                        Uplandicine 0
                                        amabiline 0
                                        indicine 0
                                        intermedine 0
                                        pyrrolizine + 0
                                        pyrrolizine alkaloid + 213
                                        symphytine + 0
                                        symphytine oxide 0
                                        triangularine 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.