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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrrolizines
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Accession:CHEBI:38522 term browser browse the term



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Echimidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP echimidine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Actn2 actinin alpha 2 decreases expression EXP echimidine results in decreased expression of ACTN2 mRNA CTD PMID:34185104 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP echimidine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP echimidine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Anapc2 anaphase promoting complex subunit 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of ANAPC2 mRNA CTD PMID:33884520 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178
JBrowse link
G Ankrd1 ankyrin repeat domain 1 decreases expression EXP echimidine results in decreased expression of ANKRD1 mRNA CTD PMID:34185104 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of AURKA mRNA CTD PMID:33884520 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G C3ar1 complement C3a receptor 1 increases expression EXP echimidine results in increased expression of C3AR1 mRNA CTD PMID:34185104 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Casp3 caspase 3 multiple interactions ISO echimidine results in increased activity of and results in increased cleavage of CASP3 protein CTD PMID:29458164 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO echimidine results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:29458164 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO echimidine results in increased activity of CASP9 protein CTD PMID:29458164 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CCNB1 mRNA CTD PMID:33884520 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CCNB2 mRNA CTD PMID:33884520 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Cdc16 cell division cycle 16 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of CDC16 mRNA CTD PMID:33884520 NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which affects the expression of CDC20 mRNA CTD PMID:33884520 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25b cell division cycle 25B multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDC25B mRNA CTD PMID:33884520 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDC25C mRNA CTD PMID:33884520 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDK1 mRNA CTD PMID:33884520 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDK2 mRNA CTD PMID:33884520 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
EXP
ISO
echimidine results in increased expression of CDKN1A mRNA
[CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of CDKN1A mRNA
CTD PMID:32419051 PMID:33884520 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CHEK1 mRNA CTD PMID:33884520 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression EXP echimidine results in increased expression of CKAP2 mRNA CTD PMID:32419051 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Ckm creatine kinase, M-type decreases expression EXP echimidine results in decreased expression of CKM mRNA CTD PMID:34185104 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression EXP echimidine results in decreased expression of CKMT2 mRNA CTD PMID:34185104 NCBI chr 2:23,079,920...23,110,518
Ensembl chr 2:23,079,918...23,110,430
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP echimidine results in decreased expression of CLEC4F mRNA CTD PMID:32419051 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression EXP echimidine results in decreased expression of COX6A2 mRNA CTD PMID:34185104 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP echimidine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases expression EXP echimidine results in decreased expression of CSRP3 mRNA CTD PMID:34185104 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
multiple interactions
ISO CYP3A4 protein results in increased metabolism of echimidine
[CYP3A4 protein results in increased metabolism of echimidine] which affects the expression of CDC20 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which affects the expression of PKMYT1 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which affects the expression of PLK2 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of ANAPC2 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of AURKA mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CCNB1 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CCNB2 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDC25B mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDC25C mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDK1 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CDK2 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of CHEK1 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of ESPL1 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of FBXO5 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of KIF11 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PLK1 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PLK4 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PPM1L mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PPP2R5D mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PRC1 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PTTG1 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of RAD21 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of STAG2 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of CDC16 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of CDKN1A mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of KIF23 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of PLK3 mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of PPP2CB mRNA; [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of PPP2R5E mRNA
CTD PMID:33884520 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 decreases expression EXP echimidine results in decreased expression of DNASE1L3 mRNA CTD PMID:34185104 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression EXP echimidine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 decreases expression EXP echimidine results in decreased expression of EEF1A2 mRNA CTD PMID:34185104 NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of ESPL1 mRNA CTD PMID:33884520 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO echimidine metabolite results in increased expression of FAS mRNA CTD PMID:30465738 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxo5 F-box protein 5 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of FBXO5 mRNA CTD PMID:33884520 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fcgr3a Fc gamma receptor IIIa increases expression EXP echimidine results in increased expression of FCGR3A mRNA CTD PMID:34185104 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Gpc1 glypican 1 decreases expression EXP echimidine results in decreased expression of GPC1 mRNA CTD PMID:34185104 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
JBrowse link
G H2ax H2A.X variant histone increases expression ISO echimidine results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hjv hemojuvelin BMP co-receptor decreases expression EXP echimidine results in decreased expression of HJV mRNA CTD PMID:34185104 NCBI chr 2:184,065,970...184,069,851
Ensembl chr 2:184,065,970...184,069,850
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases expression EXP echimidine results in decreased expression of HPGD mRNA CTD PMID:32419051 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hrc histidine rich calcium binding protein decreases expression EXP echimidine results in decreased expression of HRC mRNA CTD PMID:34185104 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression EXP echimidine results in increased expression of IFIT2 mRNA CTD PMID:32419051 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP echimidine results in decreased expression of INMT mRNA CTD PMID:32419051 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Kif11 kinesin family member 11 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of KIF11 mRNA CTD PMID:33884520 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif23 kinesin family member 23 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of KIF23 mRNA CTD PMID:33884520 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Mal mal, T-cell differentiation protein increases expression EXP echimidine results in increased expression of MAL mRNA CTD PMID:34185104 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
JBrowse link
G Mb myoglobin decreases expression EXP echimidine results in decreased expression of MB mRNA CTD PMID:34185104 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP echimidine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP echimidine results in increased expression of MKI67 mRNA CTD PMID:32419051 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP echimidine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Mybpc3 myosin binding protein C3 decreases expression EXP echimidine results in decreased expression of MYBPC3 mRNA CTD PMID:34185104 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP echimidine results in decreased expression of MYH6 mRNA CTD PMID:34185104 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myl4 myosin, light chain 4 decreases expression EXP echimidine results in decreased expression of MYL4 mRNA CTD PMID:34185104 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
JBrowse link
G Myoz2 myozenin 2 decreases expression EXP echimidine results in decreased expression of MYOZ2 mRNA CTD PMID:34185104 NCBI chr 2:211,141,463...211,168,202
Ensembl chr 2:211,141,463...211,168,221
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO echimidine results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:29458164 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which affects the expression of PKMYT1 mRNA CTD PMID:33884520 NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PLK1 mRNA CTD PMID:33884520 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk2 polo-like kinase 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which affects the expression of PLK2 mRNA CTD PMID:33884520 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Plk3 polo-like kinase 3 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of PLK3 mRNA CTD PMID:33884520 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Plk4 polo-like kinase 4 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PLK4 mRNA CTD PMID:33884520 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
G Pln phospholamban decreases expression EXP echimidine results in decreased expression of PLN mRNA CTD PMID:34185104 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Ppm1l protein phosphatase, Mg2+/Mn2+ dependent, 1L multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PPM1L mRNA CTD PMID:33884520 NCBI chr 2:153,566,653...153,839,434
Ensembl chr 2:153,566,653...153,839,434
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of PPP2CB mRNA CTD PMID:33884520 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r5d protein phosphatase 2, regulatory subunit B', delta multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PPP2R5D mRNA CTD PMID:33884520 NCBI chr 9:14,270,364...14,300,396
Ensembl chr 9:14,268,745...14,300,400
JBrowse link
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in increased expression of PPP2R5E mRNA CTD PMID:33884520 NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872
JBrowse link
G Prc1 protein regulator of cytokinesis 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PRC1 mRNA CTD PMID:33884520 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of PTTG1 mRNA CTD PMID:33884520 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rad21 RAD21 cohesin complex component multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of RAD21 mRNA CTD PMID:33884520 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
JBrowse link
G Slc13a4 solute carrier family 13 member 4 increases expression EXP echimidine results in increased expression of SLC13A4 mRNA CTD PMID:34185104 NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857
JBrowse link
G Sln sarcolipin decreases expression EXP echimidine results in decreased expression of SLN mRNA CTD PMID:34185104 NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:54,243,542...54,247,791
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP echimidine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
JBrowse link
G Stag2 stromal antigen 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of echimidine] which results in decreased expression of STAG2 mRNA CTD PMID:33884520 NCBI chr  X:120,974,687...121,105,677
Ensembl chr  X:120,974,857...121,105,677
JBrowse link
G Stc1 stanniocalcin 1 increases expression EXP echimidine results in increased expression of STC1 mRNA CTD PMID:34185104 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
JBrowse link
G Tlr8 toll-like receptor 8 increases expression EXP echimidine results in increased expression of TLR8 mRNA CTD PMID:34185104 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type decreases expression EXP echimidine results in decreased expression of TNNC1 mRNA CTD PMID:34185104 NCBI chr16:6,400,801...6,405,419
Ensembl chr16:6,402,171...6,405,634
JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression EXP echimidine results in decreased expression of TNNT2 mRNA CTD PMID:34185104 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Trim54 tripartite motif-containing 54 decreases expression EXP echimidine results in decreased expression of TRIM54 mRNA CTD PMID:34185104 NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511
JBrowse link
erucifoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2ax H2A.X variant histone increases expression ISO erucifoline results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
Heliotrine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO heliotrine results in decreased expression of ABCB11 mRNA CTD PMID:26100227 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP heliotrine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO heliotrine results in decreased expression of ABCC6 mRNA CTD PMID:26100227 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO
EXP
heliotrine results in decreased expression of ACSM3 mRNA CTD PMID:26100227 PMID:32419051 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP heliotrine results in decreased expression of ACTG2 mRNA CTD PMID:34185104 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Actn2 actinin alpha 2 decreases expression EXP heliotrine results in decreased expression of ACTN2 mRNA CTD PMID:34185104 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP heliotrine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Adgre4 adhesion G protein-coupled receptor E4 increases expression EXP heliotrine results in increased expression of ADGRE4 mRNA CTD PMID:34185104 NCBI chr 9:9,758,106...9,901,908
Ensembl chr 9:9,760,355...9,900,760
JBrowse link
G Aff3 AF4/FMR2 family, member 3 decreases expression ISO heliotrine results in decreased expression of AFF3 mRNA CTD PMID:26100227 NCBI chr 9:40,399,109...40,856,716
Ensembl chr 9:40,404,375...40,857,247
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression ISO heliotrine results in decreased expression of AGXT mRNA CTD PMID:26100227 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP heliotrine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases expression ISO heliotrine results in decreased expression of ALDH5A1 mRNA CTD PMID:26100227 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO heliotrine results in decreased expression of ALDH6A1 mRNA CTD PMID:26100227 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO heliotrine results in decreased expression of ALDH8A1 mRNA CTD PMID:26100227 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
JBrowse link
G Amz1 archaelysin family metallopeptidase 1 increases expression EXP heliotrine results in increased expression of AMZ1 mRNA CTD PMID:34185104 NCBI chr12:13,886,533...13,924,275
Ensembl chr12:13,891,123...13,909,783
JBrowse link
G Ankrd1 ankyrin repeat domain 1 decreases expression EXP heliotrine results in decreased expression of ANKRD1 mRNA CTD PMID:34185104 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Areg amphiregulin increases expression ISO heliotrine results in increased expression of AREG mRNA CTD PMID:26100227 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D increases expression EXP heliotrine results in increased expression of ATP6V1D mRNA CTD PMID:32419051 NCBI chr 6:97,656,725...97,672,211
Ensembl chr 6:97,656,576...97,672,303
JBrowse link
G C3ar1 complement C3a receptor 1 increases expression EXP heliotrine results in increased expression of C3AR1 mRNA CTD PMID:34185104 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Casp3 caspase 3 multiple interactions ISO heliotrine results in increased activity of and results in increased cleavage of CASP3 protein CTD PMID:29458164 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases cleavage ISO heliotrine results in increased cleavage of CASP8 protein CTD PMID:29458164 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO heliotrine results in increased activity of CASP9 protein CTD PMID:29458164 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccng1 cyclin G1 increases expression EXP heliotrine results in increased expression of CCNG1 mRNA CTD PMID:32419051 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP heliotrine results in increased expression of CDKN1A mRNA CTD PMID:32419051 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression EXP heliotrine results in increased expression of CKAP2 mRNA CTD PMID:32419051 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Ckm creatine kinase, M-type decreases expression EXP heliotrine results in decreased expression of CKM mRNA CTD PMID:34185104 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression EXP heliotrine results in decreased expression of CKMT2 mRNA CTD PMID:34185104 NCBI chr 2:23,079,920...23,110,518
Ensembl chr 2:23,079,918...23,110,430
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 increases expression EXP heliotrine results in increased expression of CLEC4A1 mRNA CTD PMID:34185104 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP heliotrine results in decreased expression of CLEC4F mRNA CTD PMID:32419051 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 decreases expression EXP heliotrine results in decreased expression of COX6A2 mRNA CTD PMID:34185104 NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP heliotrine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 decreases expression EXP heliotrine results in decreased expression of CSRP3 mRNA CTD PMID:34185104 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO heliotrine results in decreased expression of CYP3A5 mRNA CTD PMID:26100227 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression ISO heliotrine results in decreased expression of CYP4A22 mRNA CTD PMID:26100227 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 decreases expression ISO heliotrine results in decreased expression of CYP4F3 mRNA CTD PMID:26100227 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO heliotrine results in decreased expression of CYP7A1 mRNA CTD PMID:26100227 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO heliotrine results in decreased expression of CYP8B1 mRNA CTD PMID:26100227 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases expression EXP heliotrine results in increased expression of CYRIA mRNA CTD PMID:32419051 NCBI chr 6:35,045,208...35,150,669
Ensembl chr 6:35,045,208...35,150,668
JBrowse link
G Ddias DNA damage-induced apoptosis suppressor increases expression EXP heliotrine results in increased expression of DDIAS mRNA CTD PMID:32419051 NCBI chr 1:146,906,150...146,930,462
Ensembl chr 1:146,906,154...146,930,462
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression ISO heliotrine results in increased expression of DHRS9 mRNA CTD PMID:26100227 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
JBrowse link
G Dnase1l3 deoxyribonuclease 1-like 3 decreases expression EXP heliotrine results in decreased expression of DNASE1L3 mRNA CTD PMID:34185104 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase decreases expression ISO heliotrine results in decreased expression of DPYD mRNA CTD PMID:26100227 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression EXP heliotrine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 decreases expression EXP heliotrine results in decreased expression of EEF1A2 mRNA CTD PMID:34185104 NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
G Emilin2 elastin microfibril interfacer 2 increases expression EXP heliotrine results in increased expression of EMILIN2 mRNA CTD PMID:34185104 NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP heliotrine results in increased expression of EPHX1 mRNA CTD PMID:32419051 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression ISO heliotrine results in decreased expression of EPHX2 mRNA CTD PMID:26100227 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO
EXP
heliotrine metabolite results in increased expression of FAS mRNA
heliotrine results in increased expression of FAS mRNA
CTD PMID:30465738 PMID:32419051 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fcgr3a Fc gamma receptor IIIa increases expression EXP heliotrine results in increased expression of FCGR3A mRNA CTD PMID:34185104 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 decreases expression ISO heliotrine results in decreased expression of FMO3 mRNA CTD PMID:26100227 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 decreases expression ISO heliotrine results in decreased expression of FMO4 mRNA CTD PMID:26100227 NCBI chr13:75,154,683...75,172,932
Ensembl chr13:75,154,684...75,172,874
JBrowse link
G Gamt guanidinoacetate N-methyltransferase decreases expression ISO heliotrine results in decreased expression of GAMT mRNA CTD PMID:26100227 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO heliotrine results in increased expression of GEM mRNA CTD PMID:26100227 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gls glutaminase increases expression ISO heliotrine results in increased expression of GLS mRNA CTD PMID:26100227 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900
JBrowse link
G Glyat glycine-N-acyltransferase decreases expression ISO heliotrine results in decreased expression of GLYAT mRNA CTD PMID:26100227 NCBI chr 1:209,704,178...209,724,949
Ensembl chr 1:209,704,268...209,724,942
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 increases expression EXP heliotrine results in increased expression of GNAT1 mRNA CTD PMID:34185104 NCBI chr 8:108,350,935...108,355,671
Ensembl chr 8:108,350,935...108,355,671
JBrowse link
G Gpc1 glypican 1 decreases expression EXP heliotrine results in decreased expression of GPC1 mRNA CTD PMID:34185104 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
JBrowse link
G Gphn gephyrin decreases expression ISO heliotrine results in decreased expression of GPHN mRNA CTD PMID:26100227 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Gprc5a G protein-coupled receptor, class C, group 5, member A increases expression ISO heliotrine results in increased expression of GPRC5A mRNA CTD PMID:26100227 NCBI chr 4:167,903,542...167,922,276
Ensembl chr 4:167,903,542...167,922,260
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP heliotrine results in increased expression of GRIA3 mRNA CTD PMID:32419051 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 increases expression EXP heliotrine results in increased expression of GRK3 mRNA CTD PMID:34185104 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262
JBrowse link
G H2ax H2A.X variant histone increases expression ISO heliotrine results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hjv hemojuvelin BMP co-receptor decreases expression EXP heliotrine results in decreased expression of HJV mRNA CTD PMID:34185104 NCBI chr 2:184,065,970...184,069,851
Ensembl chr 2:184,065,970...184,069,850
JBrowse link
G Hnmt histamine N-methyltransferase decreases expression ISO heliotrine results in decreased expression of HNMT mRNA CTD PMID:26100227 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012
JBrowse link
G Hrc histidine rich calcium binding protein decreases expression EXP heliotrine results in decreased expression of HRC mRNA CTD PMID:34185104 NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 increases expression EXP heliotrine results in increased expression of HSD17B13 mRNA CTD PMID:32419051 NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166
JBrowse link
G Il17rd interleukin 17 receptor D increases expression EXP heliotrine results in increased expression of IL17RD mRNA CTD PMID:32419051 NCBI chr16:2,228,467...2,295,126
Ensembl chr16:2,228,287...2,292,556
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP heliotrine results in decreased expression of INMT mRNA CTD PMID:32419051 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression ISO heliotrine results in increased expression of ISG20 mRNA CTD PMID:26100227 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
JBrowse link
G Itgal integrin subunit alpha L increases expression EXP heliotrine results in increased expression of ITGAL mRNA CTD PMID:34185104 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression EXP heliotrine results in increased expression of ITGB2 mRNA CTD PMID:34185104 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Jam3 junctional adhesion molecule 3 increases expression EXP heliotrine results in increased expression of JAM3 mRNA CTD PMID:32419051 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355
JBrowse link
G Knl1 kinetochore scaffold 1 increases expression EXP heliotrine results in increased expression of KNL1 mRNA CTD PMID:32419051 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO heliotrine results in increased expression of MAFF mRNA CTD PMID:26100227 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mal mal, T-cell differentiation protein increases expression EXP heliotrine results in increased expression of MAL mRNA CTD PMID:34185104 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136
JBrowse link
G Maoa monoamine oxidase A decreases expression ISO heliotrine results in decreased expression of MAOA mRNA CTD PMID:26100227 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases expression ISO heliotrine results in decreased expression of MAOB mRNA CTD PMID:26100227 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like increases expression EXP heliotrine results in increased expression of MASTL mRNA CTD PMID:32419051 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
JBrowse link
G Mb myoglobin decreases expression EXP heliotrine results in decreased expression of MB mRNA CTD PMID:34185104 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP heliotrine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP heliotrine results in increased expression of MKI67 mRNA CTD PMID:32419051 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO heliotrine results in increased expression of MMP1 mRNA CTD PMID:26100227 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mok MOK protein kinase increases expression EXP heliotrine results in increased expression of MOK mRNA CTD PMID:32419051 NCBI chr 6:129,823,794...129,854,669
Ensembl chr 6:129,823,795...129,854,700
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP heliotrine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression EXP heliotrine results in increased expression of MYBL2 mRNA CTD PMID:32419051 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Mybpc3 myosin binding protein C3 decreases expression EXP heliotrine results in decreased expression of MYBPC3 mRNA CTD PMID:34185104 NCBI chr 3:77,095,165...77,113,406
Ensembl chr 3:77,095,252...77,113,405
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP heliotrine results in decreased expression of MYH6 mRNA CTD PMID:34185104 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myl4 myosin, light chain 4 decreases expression EXP heliotrine results in decreased expression of MYL4 mRNA CTD PMID:34185104 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
JBrowse link
G Myom1 myomesin 1 decreases expression EXP heliotrine results in decreased expression of MYOM1 mRNA CTD PMID:34185104 NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344
JBrowse link
G Myoz2 myozenin 2 decreases expression EXP heliotrine results in decreased expression of MYOZ2 mRNA CTD PMID:34185104 NCBI chr 2:211,141,463...211,168,202
Ensembl chr 2:211,141,463...211,168,221
JBrowse link
G Neb nebulin decreases expression ISO heliotrine results in decreased expression of NEB mRNA CTD PMID:26100227 NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574
JBrowse link
G Nnmt nicotinamide N-methyltransferase decreases expression ISO heliotrine results in decreased expression of NNMT mRNA CTD PMID:26100227 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655
JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression EXP heliotrine results in increased expression of NRCAM mRNA CTD PMID:32419051 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nrg1 neuregulin 1 increases expression EXP heliotrine results in increased expression of NRG1 mRNA CTD PMID:32419051 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO heliotrine results in decreased expression of PARP1 protein CTD PMID:29458164 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pld4 phospholipase D family, member 4 increases expression EXP heliotrine results in increased expression of PLD4 mRNA CTD PMID:34185104 NCBI chr 6:131,818,860...131,827,457
Ensembl chr 6:131,818,860...131,826,376
JBrowse link
G Pln phospholamban decreases expression EXP heliotrine results in decreased expression of PLN mRNA CTD PMID:34185104 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Pstpip2 proline-serine-threonine phosphatase-interacting protein 2 increases expression EXP heliotrine results in increased expression of PSTPIP2 mRNA CTD PMID:34185104 NCBI chr18:71,310,387...71,396,752
Ensembl chr18:71,311,020...71,395,709
JBrowse link
G Ptprd protein tyrosine phosphatase, receptor type, D decreases expression ISO heliotrine results in decreased expression of PTPRD mRNA CTD PMID:26100227 NCBI chr 5:90,046,993...90,698,977
Ensembl chr 5:90,048,966...92,369,396
JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO heliotrine results in decreased expression of RAPGEF4 mRNA CTD PMID:26100227 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO heliotrine results in increased expression of RRAD mRNA CTD PMID:26100227 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 increases expression EXP heliotrine results in increased expression of SAMSN1 mRNA CTD PMID:34185104 NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900
JBrowse link
G Sgcb sarcoglycan, beta increases expression EXP heliotrine results in increased expression of SGCB mRNA CTD PMID:32419051 NCBI chr14:34,563,614...34,578,614
Ensembl chr14:34,563,608...34,578,583
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO heliotrine results in decreased expression of SLC10A1 mRNA CTD PMID:26100227 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc13a4 solute carrier family 13 member 4 increases expression EXP heliotrine results in increased expression of SLC13A4 mRNA CTD PMID:34185104 NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857
JBrowse link
G Slc22a25 solute carrier family 22, member 25 decreases expression ISO heliotrine results in decreased expression of SLC22A9 mRNA CTD PMID:26100227 NCBI chr 1:205,338,698...205,498,486
Ensembl chr 1:205,338,699...205,433,085
JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression ISO heliotrine results in decreased expression of SLC22A7 mRNA CTD PMID:26100227 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
JBrowse link
G Slc38a7 solute carrier family 38, member 7 increases expression EXP heliotrine results in increased expression of SLC38A7 mRNA CTD PMID:34185104 NCBI chr19:9,209,203...9,225,472
Ensembl chr19:9,209,257...9,225,454
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression ISO heliotrine results in decreased expression of SLCO2B1 mRNA CTD PMID:26100227 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Sln sarcolipin decreases expression EXP heliotrine results in decreased expression of SLN mRNA CTD PMID:34185104 NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:54,243,542...54,247,791
JBrowse link
G Smpx small muscle protein, X-linked decreases expression EXP heliotrine results in decreased expression of SMPX mRNA CTD PMID:34185104 NCBI chr  X:37,233,209...37,292,266
Ensembl chr  X:37,234,294...37,276,708
JBrowse link
G Srl sarcalumenin decreases expression EXP heliotrine results in decreased expression of SRL mRNA CTD PMID:34185104 NCBI chr10:11,033,976...11,078,103
Ensembl chr10:11,034,035...11,078,101
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP heliotrine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
JBrowse link
G Stc1 stanniocalcin 1 increases expression EXP heliotrine results in increased expression of STC1 mRNA CTD PMID:34185104 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
JBrowse link
G Steap4 STEAP4 metalloreductase increases expression EXP heliotrine results in increased expression of STEAP4 mRNA CTD PMID:34185104 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 decreases expression ISO heliotrine results in decreased expression of SULT1E1 mRNA CTD PMID:26100227 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression ISO heliotrine results in decreased expression of SULT2A1 mRNA CTD PMID:26100227 NCBI chr 1:75,451,178...75,508,142
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Tenm1 teneurin transmembrane protein 1 decreases expression ISO heliotrine results in decreased expression of TENM1 mRNA CTD PMID:26100227 NCBI chr  X:121,400,466...122,289,877
Ensembl chr  X:121,403,649...122,290,207
JBrowse link
G Tenm2 teneurin transmembrane protein 2 decreases expression ISO heliotrine results in decreased expression of TENM2 mRNA CTD PMID:26100227 NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597
JBrowse link
G Tlr7 toll-like receptor 7 increases expression EXP heliotrine results in increased expression of TLR7 mRNA CTD PMID:34185104 NCBI chr  X:27,027,380...27,054,309
Ensembl chr  X:27,027,425...27,054,754
JBrowse link
G Tlr8 toll-like receptor 8 increases expression EXP heliotrine results in increased expression of TLR8 mRNA CTD PMID:34185104 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression EXP heliotrine results in increased expression of TNFRSF1B mRNA CTD PMID:34185104 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type decreases expression EXP heliotrine results in decreased expression of TNNC1 mRNA CTD PMID:34185104 NCBI chr16:6,400,801...6,405,419
Ensembl chr16:6,402,171...6,405,634
JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression EXP heliotrine results in decreased expression of TNNT2 mRNA CTD PMID:34185104 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP heliotrine results in increased expression of TOP2A mRNA CTD PMID:32419051 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Treml4 triggering receptor expressed on myeloid cells-like 4 increases expression EXP heliotrine results in increased expression of TREML4 mRNA CTD PMID:34185104 NCBI chr 9:12,718,968...12,743,879
Ensembl chr 9:12,721,815...12,743,253
JBrowse link
G Trim54 tripartite motif-containing 54 decreases expression EXP heliotrine results in decreased expression of TRIM54 mRNA CTD PMID:34185104 NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511
JBrowse link
G Tyms thymidylate synthetase increases expression EXP heliotrine results in increased expression of TYMS mRNA CTD PMID:32419051 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ugt3a2 UDP glycosyltransferase 3 family, polypeptide A2 decreases expression ISO heliotrine results in decreased expression of UGT3A1 mRNA CTD PMID:26100227 NCBI chr 2:58,327,058...58,350,186
Ensembl chr 2:58,334,603...58,350,186
JBrowse link
G Vps13b vacuolar protein sorting 13 homolog B decreases expression ISO heliotrine results in decreased expression of VPS13B mRNA CTD PMID:26100227 NCBI chr 7:66,557,862...67,128,429
Ensembl chr 7:66,558,471...67,128,429
JBrowse link
indicine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of indicine CTD PMID:33884520 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G H2ax H2A.X variant histone increases expression ISO indicine analog results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
intermedine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2ax H2A.X variant histone increases expression ISO intermedine analog results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
jacobine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2ax H2A.X variant histone increases expression ISO jacobine analog results in increased expression of H2AX protein; jacobine results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
ketorolac term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP Ketorolac results in decreased expression of CXCL1 mRNA CTD PMID:19620882 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions ISO Ketorolac inhibits the reaction [IL4 results in increased expression of CYSLTR1 mRNA] CTD PMID:19767084 NCBI chr  X:71,661,415...71,690,158
Ensembl chr  X:71,663,821...71,690,121
JBrowse link
G Epas1 endothelial PAS domain protein 1 decreases expression ISO Ketorolac results in decreased expression of EPAS1 protein CTD PMID:12912967 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Fcer1a Fc epsilon receptor Ia multiple interactions ISO Ketorolac inhibits the reaction [IL4 results in increased expression of FCER1A mRNA] CTD PMID:19767084 NCBI chr13:85,686,099...85,692,394
Ensembl chr13:85,686,092...85,692,351
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Ketorolac inhibits the reaction [IL1B protein results in increased expression of FOS mRNA] CTD PMID:10800959 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Ketorolac results in decreased expression of HIF1A protein CTD PMID:12912967 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression EXP Ketorolac results in decreased expression of ICAM1 mRNA CTD PMID:19620882 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Ketorolac co-treated with IL1B protein] results in increased secretion of Dinoprostone; Ketorolac inhibits the reaction [IL1B protein results in increased expression of FOS mRNA]; Ketorolac inhibits the reaction [IL1B protein results in increased expression of NR4A1 mRNA]; Ketorolac inhibits the reaction [IL1B protein results in increased expression of PTGER4 mRNA]; Ketorolac inhibits the reaction [IL1B protein results in increased secretion of Corticosterone] CTD PMID:10800959 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Ketorolac inhibits the reaction [IL4 results in increased activity of STAT6 protein]; Ketorolac inhibits the reaction [IL4 results in increased expression of CYSLTR1 mRNA]; Ketorolac inhibits the reaction [IL4 results in increased expression of FCER1A mRNA]; Ketorolac inhibits the reaction [IL4 results in increased phosphorylation of STAT6 protein] CTD PMID:19767084 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Mpo myeloperoxidase decreases activity EXP Ketorolac results in decreased activity of MPO CTD PMID:11996850 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions EXP Ketorolac inhibits the reaction [IL1B protein results in increased expression of NR4A1 mRNA] CTD PMID:10800959 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Ptger4 prostaglandin E receptor 4 multiple interactions EXP Ketorolac inhibits the reaction [IL1B protein results in increased expression of PTGER4 mRNA] CTD PMID:10800959 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression
decreases activity
ISO Ketorolac results in decreased expression of PTGS1 mRNA
Ketorolac results in decreased activity of PTGS1 protein
CTD PMID:17175104 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
decreases expression
ISO
EXP
Ketorolac results in increased expression of PTGS2 mRNA
Ketorolac inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Carrageenan results in increased expression of PTGS2 protein]]
Ketorolac results in decreased expression of PTGS2 mRNA
CTD PMID:17175104 PMID:17258197 PMID:19620882 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 affects expression ISO Ketorolac affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 affects expression ISO Ketorolac affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Sele selectin E decreases expression EXP Ketorolac results in decreased expression of SELE mRNA CTD PMID:19620882 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions ISO Ketorolac inhibits the reaction [IL4 results in increased activity of STAT6 protein]; Ketorolac inhibits the reaction [IL4 results in increased phosphorylation of STAT6 protein] CTD PMID:19767084 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO Ketorolac inhibits the reaction [UGT2B7 protein results in increased chemical synthesis of aldosterone 18-glucuronide]; Ketorolac inhibits the reaction [UGT2B7 protein results in increased glucuronidation of Aldosterone] CTD PMID:19740398 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
Lasiocarpine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO lasiocarpine results in decreased expression of ABCB11 mRNA CTD PMID:32234424 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP lasiocarpine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Ace angiotensin I converting enzyme decreases expression ISO lasiocarpine metabolite results in decreased expression of ACE mRNA CTD PMID:30465738 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP lasiocarpine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 increases expression ISO lasiocarpine results in increased expression of ADGRG1 mRNA CTD PMID:32234424 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide decreases expression ISO lasiocarpine results in decreased expression of ADH4 mRNA CTD PMID:32234424 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Akap5 A-kinase anchoring protein 5 increases expression ISO lasiocarpine results in increased expression of AKAP5 mRNA CTD PMID:32234424 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 decreases expression ISO lasiocarpine results in decreased expression of AKR1D1 mRNA CTD PMID:32234424 NCBI chr 4:66,154,246...66,187,505
Ensembl chr 4:66,154,248...66,186,372
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP lasiocarpine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alpi alkaline phosphatase, intestinal decreases expression ISO lasiocarpine results in decreased expression of ALPI mRNA CTD PMID:32234424 NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
JBrowse link
G Anapc1 anaphase promoting complex subunit 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ANAPC1 mRNA CTD PMID:33884520 NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273
JBrowse link
G Anapc11 anaphase promoting complex subunit 11 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of ANAPC11 mRNA CTD PMID:33884520 NCBI chr10:105,875,209...105,886,307 JBrowse link
G Anapc2 anaphase promoting complex subunit 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ANAPC2 mRNA CTD PMID:33884520 NCBI chr 3:8,086,434...8,098,182
Ensembl chr 3:8,086,462...8,098,178
JBrowse link
G Angpt1 angiopoietin 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of ANGPT1 mRNA CTD PMID:30465738 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Arg1 arginase 1 decreases expression ISO lasiocarpine results in decreased expression of ARG1 mRNA CTD PMID:32234424 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arid1a AT-rich interaction domain 1A multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ARID1A mRNA CTD PMID:33884520 NCBI chr 5:145,908,181...145,981,609
Ensembl chr 5:145,908,181...145,985,564
JBrowse link
G Arid2 AT-rich interaction domain 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ARID2 mRNA CTD PMID:33884520 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512
JBrowse link
G Arl14 ADP-ribosylation factor like GTPase 14 increases expression ISO lasiocarpine results in increased expression of ARL14 mRNA CTD PMID:32234424 NCBI chr 2:153,467,974...153,470,053
Ensembl chr 2:153,468,977...153,469,555
JBrowse link
G Aspdh aspartate dehydrogenase domain containing decreases expression ISO lasiocarpine results in decreased expression of ASPDH mRNA CTD PMID:32234424 NCBI chr 1:94,956,327...94,960,722
Ensembl chr 1:94,958,316...94,960,722
JBrowse link
G Asprv1 aspartic peptidase, retroviral-like 1 decreases expression ISO lasiocarpine results in decreased expression of ASPRV1 mRNA CTD PMID:32234424 NCBI chr 4:119,076,169...119,078,887
Ensembl chr 4:119,077,356...119,078,379
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ATM mRNA CTD PMID:33884520 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Aunip aurora kinase A and ninein interacting protein increases expression ISO lasiocarpine results in increased expression of AUNIP mRNA CTD PMID:32234424 NCBI chr 5:146,722,157...146,736,233
Ensembl chr 5:146,722,337...146,736,501
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of AURKA mRNA CTD PMID:33884520 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression EXP lasiocarpine results in decreased expression of AXL mRNA CTD PMID:32419051 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of BABAM2 mRNA CTD PMID:33884520 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Bard1 BRCA1 associated RING domain 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BARD1 mRNA CTD PMID:33884520 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 decreases expression ISO lasiocarpine results in decreased expression of BDH1 mRNA CTD PMID:32234424 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
JBrowse link
G Blm BLM RecQ like helicase increases expression
multiple interactions
ISO lasiocarpine results in increased expression of BLM mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BLM mRNA
CTD PMID:32234424 PMID:33884520 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Bora bora, aurora kinase A activator multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BORA mRNA CTD PMID:33884520 NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression
multiple interactions
ISO lasiocarpine results in increased expression of BRCA1 mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRCA1 mRNA
CTD PMID:32234424 PMID:33884520 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated increases expression
multiple interactions
ISO lasiocarpine results in increased expression of BRCA2 mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRCA2 mRNA
CTD PMID:32234424 PMID:33884520 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brd7 bromodomain containing 7 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRD7 mRNA CTD PMID:33884520 NCBI chr19:18,708,792...18,737,500
Ensembl chr19:18,709,022...18,737,494
JBrowse link
G Brip1 BRCA1 interacting helicase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRIP1 mRNA CTD PMID:33884520 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Capn1 calpain 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of CAPN1 mRNA CTD PMID:33884520 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177
JBrowse link
G Casp16 caspase 16 decreases expression ISO lasiocarpine results in decreased expression of CASP16P mRNA CTD PMID:32234424 NCBI chr10:12,586,009...12,592,023 JBrowse link
G Ccdc152 coiled-coil domain containing 152 increases expression ISO lasiocarpine results in increased expression of CCDC152 mRNA CTD PMID:32234424 NCBI chr 2:52,507,987...52,532,880
Ensembl chr 2:52,507,981...52,532,826
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CCNB1 mRNA CTD PMID:33884520 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CCNB2 mRNA CTD PMID:33884520 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccne2 cyclin E2 increases expression ISO lasiocarpine results in increased expression of CCNE2 mRNA CTD PMID:32234424 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng1 cyclin G1 increases expression EXP lasiocarpine results in increased expression of CCNG1 mRNA CTD PMID:32419051 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cd83 CD83 molecule increases expression ISO lasiocarpine results in increased expression of CD83 mRNA CTD PMID:32234424 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cdc16 cell division cycle 16 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC16 mRNA CTD PMID:33884520 NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC20 mRNA CTD PMID:33884520 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc23 cell division cycle 23 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of CDC23 mRNA CTD PMID:33884520 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
JBrowse link
G Cdc25a cell division cycle 25A increases expression
multiple interactions
ISO lasiocarpine results in increased expression of CDC25A mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC25A mRNA
CTD PMID:32234424 PMID:33884520 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25b cell division cycle 25B multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC25B mRNA CTD PMID:33884520 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC25C mRNA CTD PMID:33884520 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc42bpg CDC42 binding protein kinase gamma increases expression ISO lasiocarpine results in increased expression of CDC42BPG mRNA CTD PMID:32234424 NCBI chr 1:203,608,339...203,628,502
Ensembl chr 1:203,608,574...203,628,502
JBrowse link
G Cdc45 cell division cycle 45 increases expression ISO lasiocarpine results in increased expression of CDC45 mRNA CTD PMID:32234424 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdc6 cell division cycle 6 increases expression ISO lasiocarpine results in increased expression of CDC6 mRNA CTD PMID:32234424 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdc7 cell division cycle 7 increases expression
multiple interactions
ISO lasiocarpine results in increased expression of CDC7 mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC7 mRNA
CTD PMID:32234424 PMID:33884520 NCBI chr14:2,804,660...2,824,796
Ensembl chr14:2,804,661...2,824,778
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDK1 mRNA CTD PMID:33884520 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDK2 mRNA CTD PMID:33884520 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
EXP
ISO
lasiocarpine results in increased expression of CDKN1A mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of CDKN1A mRNA
CTD PMID:32419051 PMID:33884520 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdt1 chromatin licensing and DNA replication factor 1 increases expression ISO lasiocarpine results in increased expression of CDT1 mRNA CTD PMID:32234424 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Cel carboxyl ester lipase increases expression ISO lasiocarpine results in increased expression of CEL mRNA CTD PMID:32234424 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CHEK1 mRNA CTD PMID:33884520 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Cldn14 claudin 14 decreases expression ISO lasiocarpine results in decreased expression of CLDN14 mRNA CTD PMID:32234424 NCBI chr11:33,232,281...33,329,440
Ensembl chr11:33,232,220...33,329,171
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP lasiocarpine results in decreased expression of CLEC4F mRNA CTD PMID:32419051 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
JBrowse link
G Clspn claspin increases expression
multiple interactions
ISO lasiocarpine results in increased expression of CLSPN mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CLSPN mRNA
CTD PMID:32234424 PMID:33884520 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases expression ISO lasiocarpine results in decreased expression of COL5A2 mRNA CTD PMID:32234424 NCBI chr 9:47,448,736...47,598,396
Ensembl chr 9:47,448,736...47,598,154
JBrowse link
G Crppa CDP-L-ribitol pyrophosphorylase A decreases expression ISO lasiocarpine results in decreased expression of CRPPA mRNA CTD PMID:32234424 NCBI chr 6:53,120,264...53,397,030
Ensembl chr 6:53,121,438...53,397,028
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP lasiocarpine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Cyba cytochrome b-245 alpha chain decreases expression ISO lasiocarpine results in decreased expression of CYBA mRNA CTD PMID:32234424 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO lasiocarpine results in increased expression of CYP1A1 mRNA CTD PMID:32234424 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression ISO lasiocarpine results in decreased expression of CYP2A7 mRNA CTD PMID:32234424 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO lasiocarpine results in decreased expression of CYP2E1 mRNA CTD PMID:32234424 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
multiple interactions
EXP
ISO
CYP3A2 protein results in increased metabolism of lasiocarpine
CYP3A4 protein results in increased metabolism of lasiocarpine
[CYP3A4 protein results in increased metabolism of lasiocarpine] which affects the expression of KIF23 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ANAPC1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ANAPC2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ARID1A mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ARID2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ATM mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ATRIP mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of AURKA mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BARD1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BLM mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BORA mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRCA1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRCA2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRD7 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of BRIP1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CCNB1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CCNB2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC16 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC20 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC25A mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC25B mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC25C mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDC7 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDK1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CDK2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CHEK1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of CLSPN mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F3 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F5 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F8 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ESPL1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of FANCA mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of FANCB mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of FANCD2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of FBXO5 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of HLTF mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of KIF11 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MLH1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MRE11 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MSH2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MSH6 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PHF10 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PLK1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PLK4 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of POU2F1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PPP2R5D mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PRC1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PTTG1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RAD1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RAD17 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RAD21 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RBBP8 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RBL1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC3 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC4 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC5 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RPA1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of SLC19A1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of SMARCC1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of SMC1A mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of SMC3 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of STAG2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of TLK1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of TOP2A mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of TOPBP1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of WEE1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of ANAPC11 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of BABAM2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of CAPN1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of CDC23 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of CDKN1A mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of E2F7 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of GADD45A mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of PLK2 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of PLK3 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of PPP2CB mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of STAT1 mRNA; [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased phosphorylation of H2AFX protein
CTD PMID:31103741 PMID:33884520 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases metabolic processing EXP CYP3A23-3A1 protein results in increased metabolism of lasiocarpine CTD PMID:31103741 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing ISO CYP3A5 protein results in increased metabolism of lasiocarpine CTD PMID:31103741 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO lasiocarpine results in decreased expression of CYP7A1 mRNA CTD PMID:32234424 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyria CYFIP related Rac1 interactor A increases expression EXP lasiocarpine results in increased expression of CYRIA mRNA CTD PMID:32419051 NCBI chr 6:35,045,208...35,150,669
Ensembl chr 6:35,045,208...35,150,668
JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 increases expression ISO lasiocarpine results in increased expression of DSCC1 mRNA CTD PMID:32234424 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog increases expression ISO lasiocarpine results in increased expression of DTL mRNA CTD PMID:32234424 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F1 mRNA CTD PMID:33884520 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO lasiocarpine results in increased expression of E2F2 mRNA CTD PMID:32234424 NCBI chr 5:148,399,193...148,422,595
Ensembl chr 5:148,399,642...148,421,217
JBrowse link
G E2f3 E2F transcription factor 3 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F3 mRNA CTD PMID:33884520 NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253
JBrowse link
G E2f5 E2F transcription factor 5 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F5 mRNA CTD PMID:33884520 NCBI chr 2:86,997,331...87,012,901
Ensembl chr 2:86,997,332...87,012,990
JBrowse link
G E2f7 E2F transcription factor 7 increases expression
multiple interactions
ISO lasiocarpine results in increased expression of E2F7 mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of E2F7 mRNA
CTD PMID:32234424 PMID:33884520 NCBI chr 7:46,150,533...46,192,739
Ensembl chr 7:46,151,293...46,192,734
JBrowse link
G E2f8 E2F transcription factor 8 increases expression
multiple interactions
ISO lasiocarpine results in increased expression of E2F8 mRNA
[CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of E2F8 mRNA
CTD PMID:32234424 PMID:33884520 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Eda2r ectodysplasin A2 receptor increases expression EXP lasiocarpine results in increased expression of EDA2R mRNA CTD PMID:32419051 NCBI chr  X:62,224,763...62,269,344
Ensembl chr  X:62,228,229...62,269,268
JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 decreases expression ISO lasiocarpine results in decreased expression of ENOX1 mRNA CTD PMID:32234424 NCBI chr15:52,517,833...53,079,752
Ensembl chr15:52,515,178...53,079,749
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of ESPL1 mRNA CTD PMID:33884520 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Exo1 exonuclease 1 increases expression ISO lasiocarpine results in increased expression of EXO1 mRNA CTD PMID:32234424 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO lasiocarpine results in decreased expression of FABP1 mRNA CTD PMID:32234424 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fam151a family with sequence similarity 151, member A decreases expression ISO lasiocarpine results in decreased expression of FAM151A mRNA CTD PMID:32234424 NCBI chr 5:121,514,804...121,527,555
Ensembl chr 5:121,514,804...121,527,555
JBrowse link
G Fanca FA complementation group A multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of FANCA mRNA CTD PMID:33884520 NCBI chr19:51,304,021...51,362,586
Ensembl chr19:51,304,021...51,362,527
JBrowse link
G Fancb FA complementation group B multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of FANCB mRNA CTD PMID:33884520 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Fancd2 FA complementation group D2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of FANCD2 mRNA CTD PMID:33884520 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Fancg FA complementation group G increases expression ISO lasiocarpine results in increased expression of FANCG mRNA CTD PMID:32234424 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029
JBrowse link
G Fanci FA complementation group I increases expression ISO lasiocarpine results in increased expression of FANCI mRNA CTD PMID:32234424 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO lasiocarpine metabolite results in increased expression of FAS mRNA CTD PMID:30465738 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxo5 F-box protein 5 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of FBXO5 mRNA CTD PMID:33884520 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fcna ficolin A decreases expression EXP lasiocarpine results in decreased expression of FCNA mRNA CTD PMID:32419051 NCBI chr 3:8,445,904...8,449,128
Ensembl chr 3:8,445,907...8,449,105
JBrowse link
G Fendrr FOXF1 adjacent non-coding developmental regulatory RNA increases expression ISO lasiocarpine results in increased expression of FENDRR mRNA CTD PMID:32234424 NCBI chr19:49,127,225...49,152,779
Ensembl chr19:49,121,214...49,153,240
JBrowse link
G Fgf13 fibroblast growth factor 13 decreases expression ISO lasiocarpine results in decreased expression of FGF13 mRNA CTD PMID:32234424 NCBI chr  X:137,276,498...137,800,056
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO lasiocarpine metabolite results in decreased expression of FGF2 mRNA CTD PMID:30465738 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase decreases expression ISO lasiocarpine results in decreased expression of FHIT mRNA CTD PMID:32234424 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of FN1 mRNA CTD PMID:30465738 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO lasiocarpine results in increased expression of FOSL1 mRNA CTD PMID:32234424 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO lasiocarpine results in decreased expression of G6PC1 mRNA CTD PMID:32234424 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of GADD45A mRNA CTD PMID:33884520 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO lasiocarpine results in increased expression of GDF15 mRNA CTD PMID:32234424 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gnmt glycine N-methyltransferase decreases expression ISO lasiocarpine results in decreased expression of GNMT mRNA CTD PMID:32234424 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Gpc6 glypican 6 decreases expression ISO lasiocarpine results in decreased expression of GPC6 mRNA CTD PMID:32234424 NCBI chr15:94,030,218...95,027,883
Ensembl chr15:94,029,884...95,024,006
JBrowse link
G Gpr161 G protein-coupled receptor 161 increases expression ISO lasiocarpine results in increased expression of GPR161 mRNA CTD PMID:32234424 NCBI chr13:77,578,257...77,623,661
Ensembl chr13:77,577,739...77,619,613
JBrowse link
G Gpt glutamic--pyruvic transaminase affects activity EXP lasiocarpine affects the activity of GPT protein CTD PMID:32419051 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Grap2 GRB2-related adaptor protein 2 increases expression ISO lasiocarpine results in increased expression of GRAP2 mRNA CTD PMID:32234424 NCBI chr 7:112,117,142...112,190,880
Ensembl chr 7:112,117,142...112,190,877
JBrowse link
G Gucy2d guanylate cyclase 2D, retinal decreases expression ISO lasiocarpine results in decreased expression of GUCY2D mRNA CTD PMID:32234424 NCBI chr10:53,954,918...53,975,576
Ensembl chr10:53,959,010...53,974,067
JBrowse link
G Gzma granzyme A decreases expression EXP lasiocarpine results in decreased expression of GZMA mRNA CTD PMID:32419051 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation
increases expression
EXP
ISO
lasiocarpine results in increased phosphorylation of H2AX protein
lasiocarpine results in increased expression of H2AX protein
CTD PMID:31154085 PMID:31289892 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hells helicase, lymphoid specific increases expression ISO lasiocarpine results in increased expression of HELLS mRNA CTD PMID:32234424 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
JBrowse link
G Hhat hedgehog acyltransferase decreases expression ISO lasiocarpine results in decreased expression of HHAT mRNA CTD PMID:32234424 NCBI chr13:104,024,507...104,283,581
Ensembl chr13:104,010,916...104,282,893
JBrowse link
G Hjv hemojuvelin BMP co-receptor decreases expression ISO lasiocarpine results in decreased expression of HJV mRNA CTD PMID:32234424 NCBI chr 2:184,065,970...184,069,851
Ensembl chr 2:184,065,970...184,069,850
JBrowse link
G Hltf helicase-like transcription factor multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of HLTF mRNA CTD PMID:33884520 NCBI chr 2:102,549,724...102,609,492
Ensembl chr 2:102,549,724...102,609,327
JBrowse link
G Hmcn1 hemicentin 1 decreases expression ISO lasiocarpine results in decreased expression of HMCN1 mRNA CTD PMID:32234424 NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524
JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 increases expression EXP lasiocarpine results in increased expression of HMGN5 mRNA CTD PMID:34185104 NCBI chr  X:74,085,871...74,094,488 JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase decreases expression EXP lasiocarpine results in decreased expression of HPGD mRNA CTD PMID:32419051 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hs6st3 heparan sulfate 6-O-sulfotransferase 3 decreases expression ISO lasiocarpine results in decreased expression of HS6ST3 mRNA CTD PMID:32234424 NCBI chr15:96,281,502...97,000,804
Ensembl chr15:96,281,646...97,000,462
JBrowse link
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 increases expression EXP lasiocarpine results in increased expression of HSD17B13 mRNA CTD PMID:32419051 NCBI chr14:5,751,697...5,766,809
Ensembl chr14:5,752,132...5,768,166
JBrowse link
G Igsf23 immunoglobulin superfamily, member 23 decreases expression ISO lasiocarpine results in decreased expression of IGSF23 mRNA CTD PMID:32234424 NCBI chr 1:79,591,059...79,606,323
Ensembl chr 1:79,592,088...79,610,438
JBrowse link
G Il11 interleukin 11 increases expression ISO lasiocarpine metabolite results in increased expression of IL11 mRNA CTD PMID:30465738 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
JBrowse link
G Il17rd interleukin 17 receptor D increases expression EXP lasiocarpine results in increased expression of IL17RD mRNA CTD PMID:32419051 NCBI chr16:2,228,467...2,295,126
Ensembl chr16:2,228,287...2,292,556
JBrowse link
G Il1b interleukin 1 beta increases expression ISO lasiocarpine metabolite results in increased expression of IL1B mRNA CTD PMID:30465738 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 decreases expression ISO lasiocarpine results in decreased expression of IMMP2L mRNA CTD PMID:32234424 NCBI chr 6:58,070,035...58,970,165
Ensembl chr 6:58,070,283...58,969,840
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression ISO lasiocarpine results in increased expression of INPP5D mRNA CTD PMID:32234424 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Itga8 integrin subunit alpha 8 decreases expression ISO lasiocarpine results in decreased expression of ITGA8 mRNA CTD PMID:32234424 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
JBrowse link
G Jam3 junctional adhesion molecule 3 increases expression EXP lasiocarpine results in increased expression of JAM3 mRNA CTD PMID:32419051 NCBI chr 8:25,508,461...25,569,306
Ensembl chr 8:25,507,057...25,569,355
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 decreases expression ISO lasiocarpine results in decreased expression of KCNMA1 mRNA CTD PMID:32234424 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kif11 kinesin family member 11 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of KIF11 mRNA CTD PMID:33884520 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif23 kinesin family member 23 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which affects the expression of KIF23 mRNA CTD PMID:33884520 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kmo kynurenine 3-monooxygenase decreases expression ISO lasiocarpine results in decreased expression of KMO mRNA CTD PMID:32234424 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 increases expression ISO lasiocarpine results in increased expression of LAMP3 mRNA CTD PMID:32234424 NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO lasiocarpine results in increased expression of LIF mRNA CTD PMID:32234424 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lingo4 leucine rich repeat and Ig domain containing 4 decreases expression ISO lasiocarpine results in decreased expression of LINGO4 mRNA CTD PMID:32234424 NCBI chr 2:182,014,326...182,040,787
Ensembl chr 2:182,014,326...182,040,787
JBrowse link
G LOC498265 similar to hypothetical protein FLJ10706 increases expression ISO lasiocarpine results in increased expression of C1ORF112 mRNA CTD PMID:32234424 NCBI chr13:76,301,914...76,345,842
Ensembl chr13:76,301,918...76,345,804
JBrowse link
G Lrmda leucine rich melanocyte differentiation associated decreases expression ISO lasiocarpine results in decreased expression of LRMDA mRNA CTD PMID:32234424 NCBI chr15:1,223,098...2,284,764
Ensembl chr15:1,225,710...2,284,749
JBrowse link
G Lrrc39 leucine rich repeat containing 39 decreases expression ISO lasiocarpine results in decreased expression of LRRC39 mRNA CTD PMID:32234424 NCBI chr 2:204,516,122...204,535,463
Ensembl chr 2:204,516,123...204,535,463
JBrowse link
G Lzts1 leucine zipper tumor suppressor 1 increases expression ISO lasiocarpine results in increased expression of LZTS1 mRNA CTD PMID:32234424 NCBI chr16:20,542,756...20,598,204
Ensembl chr16:20,542,809...20,598,203
JBrowse link
G Mab21l4 mab-21 like 4 decreases expression ISO lasiocarpine results in decreased expression of MAB21L4 mRNA CTD PMID:32234424 NCBI chr 9:93,690,455...93,701,267
Ensembl chr 9:93,690,999...93,700,506
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 decreases expression ISO lasiocarpine results in decreased expression of MACROD2 mRNA CTD PMID:32234424 NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492
JBrowse link
G Mbl2 mannose binding lectin 2 decreases expression ISO lasiocarpine results in decreased expression of MBL2 mRNA CTD PMID:32234424 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor increases expression ISO lasiocarpine results in increased expression of MCM10 mRNA CTD PMID:32234424 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP lasiocarpine results in increased expression of MGMT mRNA CTD PMID:32419051 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mlh1 mutL homolog 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MLH1 mRNA CTD PMID:33884520 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Mnd1 meiotic nuclear divisions 1 increases expression ISO lasiocarpine results in increased expression of MND1 mRNA CTD PMID:32234424 NCBI chr 2:169,433,538...169,496,081
Ensembl chr 2:169,433,540...169,496,096
JBrowse link
G Mpp2 MAGUK p55 scaffold protein 2 increases expression ISO lasiocarpine results in increased expression of MPP2 mRNA CTD PMID:32234424 NCBI chr10:87,011,434...87,043,883
Ensembl chr10:87,011,434...87,043,896
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MRE11 mRNA CTD PMID:33884520 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Msh2 mutS homolog 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MSH2 mRNA CTD PMID:33884520 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh6 mutS homolog 6 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of MSH6 mRNA CTD PMID:33884520 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Muc13 mucin 13, cell surface associated increases expression ISO lasiocarpine results in increased expression of MUC13 mRNA CTD PMID:32234424 NCBI chr11:66,957,208...66,980,264
Ensembl chr11:66,960,595...66,984,727
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression EXP lasiocarpine results in increased expression of MYBL1 mRNA CTD PMID:32419051 NCBI chr 5:9,582,905...9,618,179
Ensembl chr 5:9,582,934...9,618,183
JBrowse link
G Mybl2 MYB proto-oncogene like 2 increases expression ISO
EXP
lasiocarpine results in increased expression of MYBL2 mRNA CTD PMID:32234424 PMID:32419051 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Myo10 myosin X increases expression ISO lasiocarpine results in increased expression of MYO10 mRNA CTD PMID:32234424 NCBI chr 2:76,100,962...76,304,164
Ensembl chr 2:76,100,987...76,303,030
JBrowse link
G Naaladl2 N-acetylated alpha-linked acidic dipeptidase-like 2 decreases expression ISO lasiocarpine results in decreased expression of NAALADL2 mRNA CTD PMID:32234424 NCBI chr 2:106,639,146...107,992,218
Ensembl chr 2:106,645,608...107,991,689
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO lasiocarpine results in increased expression of NCF2 mRNA CTD PMID:32234424 NCBI chr13:64,955,502...64,986,289
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Nectin4 nectin cell adhesion molecule 4 increases expression ISO lasiocarpine results in increased expression of NECTIN4 mRNA CTD PMID:32234424 NCBI chr13:83,802,589...83,821,711
Ensembl chr13:83,803,184...83,821,709
JBrowse link
G Ninl ninein-like decreases expression ISO lasiocarpine results in decreased expression of NINL mRNA CTD PMID:32234424 NCBI chr 3:139,748,353...139,814,683
Ensembl chr 3:139,748,355...139,814,622
JBrowse link
G Npas3 neuronal PAS domain protein 3 decreases expression ISO lasiocarpine results in decreased expression of NPAS3 mRNA CTD PMID:32234424 NCBI chr 6:70,702,773...71,527,928
Ensembl chr 6:70,703,170...71,524,884
JBrowse link
G Npr1 natriuretic peptide receptor 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of NPR1 mRNA CTD PMID:30465738 NCBI chr 2:175,934,181...175,950,118
Ensembl chr 2:175,934,181...175,949,505
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO lasiocarpine results in decreased expression of NR0B2 mRNA CTD PMID:32234424 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases expression ISO lasiocarpine results in decreased expression of NR1I3 mRNA CTD PMID:32234424 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression EXP lasiocarpine results in increased expression of NRCAM mRNA CTD PMID:32419051 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nrgn neurogranin increases expression ISO lasiocarpine results in increased expression of NRGN mRNA CTD PMID:32234424 NCBI chr 8:37,255,462...37,263,659
Ensembl chr 8:37,256,930...37,257,516
JBrowse link
G Nts neurotensin decreases expression ISO lasiocarpine results in decreased expression of NTS mRNA CTD PMID:32234424 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression EXP lasiocarpine results in increased expression of NUPR1 mRNA CTD PMID:32419051 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Orc1 origin recognition complex, subunit 1 increases expression ISO lasiocarpine results in increased expression of ORC1 mRNA CTD PMID:32234424 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375
JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 decreases expression ISO lasiocarpine results in decreased expression of PAK5 mRNA CTD PMID:32234424 NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of PECAM1 mRNA CTD PMID:30465738 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 decreases expression ISO lasiocarpine results in decreased expression of PFKFB1 mRNA CTD PMID:32234424 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 decreases expression ISO lasiocarpine results in decreased expression of PGLYRP2 mRNA CTD PMID:32234424 NCBI chr 7:11,418,674...11,432,162
Ensembl chr 7:11,418,880...11,427,773
JBrowse link
G Phf10 PHD finger protein 10 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PHF10 mRNA CTD PMID:33884520 NCBI chr 1:55,952,249...55,968,994
Ensembl chr 1:55,952,253...55,969,038
JBrowse link
G Pklr pyruvate kinase L/R decreases expression ISO lasiocarpine results in decreased expression of PKLR mRNA CTD PMID:32234424 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Plg plasminogen decreases expression ISO lasiocarpine results in decreased expression of PLG mRNA CTD PMID:32234424 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PLK1 mRNA CTD PMID:33884520 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk2 polo-like kinase 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of PLK2 mRNA CTD PMID:33884520 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Plk3 polo-like kinase 3 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of PLK3 mRNA CTD PMID:33884520 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Plk4 polo-like kinase 4 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PLK4 mRNA CTD PMID:33884520 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
G Pltp phospholipid transfer protein decreases expression EXP lasiocarpine results in decreased expression of PLTP mRNA CTD PMID:32419051 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit increases expression ISO lasiocarpine results in increased expression of POLE2 mRNA CTD PMID:32234424 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
JBrowse link
G Polq DNA polymerase theta increases expression ISO lasiocarpine results in increased expression of POLQ mRNA CTD PMID:32234424 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878
JBrowse link
G Pou2f1 POU class 2 homeobox 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of POU2F1 mRNA CTD PMID:33884520 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of PPP2CB mRNA CTD PMID:33884520 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta decreases expression ISO lasiocarpine results in decreased expression of PPP2R2B mRNA CTD PMID:32234424 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
JBrowse link
G Ppp2r5d protein phosphatase 2, regulatory subunit B', delta multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PPP2R5D mRNA CTD PMID:33884520 NCBI chr 9:14,270,364...14,300,396
Ensembl chr 9:14,268,745...14,300,400
JBrowse link
G Prc1 protein regulator of cytokinesis 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PRC1 mRNA CTD PMID:33884520 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase decreases expression ISO lasiocarpine results in decreased expression of PRKN mRNA CTD PMID:32234424 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Psmc3ip PSMC3 interacting protein increases expression ISO lasiocarpine results in increased expression of PSMC3IP mRNA CTD PMID:32234424 NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423
JBrowse link
G Ptgis prostaglandin I2 synthase decreases expression ISO lasiocarpine metabolite results in decreased expression of PTGIS mRNA; lasiocarpine metabolite results in decreased expression of PTGIS protein CTD PMID:30465738 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO lasiocarpine metabolite results in increased expression of PTGS2 mRNA; lasiocarpine metabolite results in increased expression of PTGS2 protein CTD PMID:30465738 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of PTTG1 mRNA CTD PMID:33884520 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RAD1 mRNA CTD PMID:33884520 NCBI chr 2:59,461,597...59,469,707
Ensembl chr 2:59,461,607...59,469,689
JBrowse link
G Rad17 RAD17 checkpoint clamp loader component multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RAD17 mRNA CTD PMID:33884520 NCBI chr 2:31,764,260...31,794,542
Ensembl chr 2:31,764,261...31,794,072
JBrowse link
G Rad21 RAD21 cohesin complex component multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RAD21 mRNA CTD PMID:33884520 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
JBrowse link
G Rad51b RAD51 paralog B decreases expression ISO lasiocarpine results in decreased expression of RAD51B mRNA CTD PMID:32234424 NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RBBP8 mRNA CTD PMID:33884520 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RBL1 mRNA CTD PMID:33884520 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Rdh16 retinol dehydrogenase 16 decreases expression ISO lasiocarpine results in decreased expression of RDH16 mRNA CTD PMID:32234424 NCBI chr 7:63,616,724...63,624,120
Ensembl chr 7:63,597,536...63,624,124
JBrowse link
G Rfc1 replication factor C subunit 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC1 mRNA CTD PMID:33884520 NCBI chr14:42,966,279...43,041,372
Ensembl chr14:42,966,324...43,041,370
JBrowse link
G Rfc2 replication factor C subunit 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC2 mRNA CTD PMID:33884520 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557
JBrowse link
G Rfc3 replication factor C subunit 3 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC3 mRNA CTD PMID:33884520 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
JBrowse link
G Rfc4 replication factor C subunit 4 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC4 mRNA CTD PMID:33884520 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122
JBrowse link
G Rfc5 replication factor C subunit 5 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RFC5 mRNA CTD PMID:33884520 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
G RGD1307443 similar to mKIAA0319 protein increases expression ISO lasiocarpine results in increased expression of KIAA0319 mRNA CTD PMID:32234424 NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653
JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO lasiocarpine results in increased expression of RGS16 mRNA CTD PMID:32234424 NCBI chr13:65,887,788...65,891,232
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Rhbdl3 rhomboid like 3 increases expression ISO lasiocarpine results in increased expression of RHBDL3 mRNA CTD PMID:32234424 NCBI chr10:65,299,250...65,354,099
Ensembl chr10:65,299,194...65,354,099
JBrowse link
G Rhbg Rh family B glycoprotein decreases expression ISO lasiocarpine results in decreased expression of RHBG mRNA CTD PMID:32234424 NCBI chr 2:173,704,852...173,717,380
Ensembl chr 2:173,704,562...173,717,321
JBrowse link
G Rpa1 replication protein A1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of RPA1 mRNA CTD PMID:33884520 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression ISO lasiocarpine results in increased expression of RRAD mRNA CTD PMID:32234424 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
JBrowse link
G S100a2 S100 calcium binding protein A2 increases expression ISO lasiocarpine results in increased expression of S100A2 mRNA CTD PMID:32234424 NCBI chr 2:176,075,060...176,078,782 JBrowse link
G Sbk1 SH3 domain binding kinase 1 increases expression ISO lasiocarpine results in increased expression of SBK1 mRNA CTD PMID:32234424 NCBI chr 1:180,807,092...180,851,910
Ensembl chr 1:180,807,099...180,851,885
JBrowse link
G Sdk1 sidekick cell adhesion molecule 1 decreases expression ISO lasiocarpine results in decreased expression of SDK1 mRNA CTD PMID:32234424 NCBI chr12:12,378,074...13,363,934
Ensembl chr12:12,380,524...13,363,976
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO lasiocarpine results in increased expression of SERPINB2 mRNA CTD PMID:32234424 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Sfn stratifin increases expression ISO lasiocarpine results in increased expression of SFN mRNA CTD PMID:32234424 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 decreases expression ISO lasiocarpine results in decreased expression of SH3RF3 mRNA CTD PMID:32234424 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257
JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of SLC19A1 mRNA CTD PMID:33884520 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972
JBrowse link
G Slc27a5 solute carrier family 27 member 5 decreases expression ISO lasiocarpine results in decreased expression of SLC27A5 mRNA CTD PMID:32234424 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of SMARCC1 mRNA CTD PMID:33884520 NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720
JBrowse link
G Smc1a structural maintenance of chromosomes 1A multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of SMC1A mRNA CTD PMID:33884520 NCBI chr  X:21,103,323...21,148,053
Ensembl chr  X:21,103,282...21,148,056
JBrowse link
G Smc3 structural maintenance of chromosomes 3 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of SMC3 mRNA CTD PMID:33884520 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 decreases expression ISO lasiocarpine results in decreased expression of SMPD3 mRNA CTD PMID:32234424 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
JBrowse link
G Sparcl1 SPARC like 1 decreases expression ISO lasiocarpine results in decreased expression of SPARCL1 mRNA CTD PMID:32234424 NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865
JBrowse link
G Spock3 SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 decreases expression ISO lasiocarpine results in decreased expression of SPOCK3 mRNA CTD PMID:32234424 NCBI chr16:26,382,895...26,815,943
Ensembl chr16:26,383,383...26,815,205
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases expression ISO lasiocarpine results in increased expression of SRC mRNA CTD PMID:32234424 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP lasiocarpine results in decreased expression of STAC3 mRNA CTD PMID:32419051 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
JBrowse link
G Stag2 stromal antigen 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of STAG2 mRNA CTD PMID:33884520 NCBI chr  X:120,974,687...121,105,677
Ensembl chr  X:120,974,857...121,105,677
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in increased expression of STAT1 mRNA CTD PMID:33884520 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stc1 stanniocalcin 1 increases expression EXP lasiocarpine results in increased expression of STC1 mRNA CTD PMID:34185104 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
JBrowse link
G Stk31 serine threonine kinase 31 decreases expression ISO lasiocarpine results in decreased expression of STK31 mRNA CTD PMID:32234424 NCBI chr 4:78,370,691...78,467,599
Ensembl chr 4:78,370,649...78,466,240
JBrowse link
G Sucnr1 succinate receptor 1 decreases expression ISO lasiocarpine results in decreased expression of SUCNR1 mRNA CTD PMID:32234424 NCBI chr 2:144,219,066...144,230,568
Ensembl chr 2:144,219,122...144,230,034
JBrowse link
G Sugct succinylCoA:glutarate-CoA transferase decreases expression ISO lasiocarpine results in decreased expression of SUGCT mRNA CTD PMID:32234424 NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376
JBrowse link
G Tcf19 transcription factor 19 increases expression ISO lasiocarpine results in increased expression of TCF19 mRNA CTD PMID:32234424 NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271
JBrowse link
G Tek TEK receptor tyrosine kinase decreases expression ISO lasiocarpine metabolite results in decreased expression of TEK mRNA CTD PMID:30465738 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
JBrowse link
G Tex15 testis expressed 15, meiosis and synapsis associated increases expression ISO lasiocarpine results in increased expression of TEX15 mRNA CTD PMID:32234424 NCBI chr16:58,598,991...58,659,005
Ensembl chr16:58,598,989...58,658,467
JBrowse link
G Tfpi tissue factor pathway inhibitor decreases expression ISO lasiocarpine metabolite results in decreased expression of TFPI mRNA CTD PMID:30465738 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO lasiocarpine metabolite results in decreased expression of TGFB1 mRNA CTD PMID:30465738 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thrsp thyroid hormone responsive decreases expression ISO lasiocarpine results in decreased expression of THRSP mRNA CTD PMID:32234424 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Tlk1 tousled-like kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of TLK1 mRNA CTD PMID:33884520 NCBI chr 3:55,520,559...55,627,580
Ensembl chr 3:55,503,358...55,691,968
JBrowse link
G Tlr8 toll-like receptor 8 increases expression EXP lasiocarpine results in increased expression of TLR8 mRNA CTD PMID:34185104 NCBI chr  X:27,091,780...27,116,092
Ensembl chr  X:27,091,778...27,116,549
JBrowse link
G Tmem266 transmembrane protein 266 decreases expression ISO lasiocarpine results in decreased expression of TMEM266 mRNA CTD PMID:32234424 NCBI chr 8:55,707,122...55,820,692
Ensembl chr 8:55,707,122...55,820,692
JBrowse link
G Tmsb15b2 thymosin beta 15B2 increases expression ISO lasiocarpine results in increased expression of TMSB15A mRNA CTD PMID:32234424 NCBI chr  X:100,298,705...100,300,820
Ensembl chr  X:100,298,514...100,300,886
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO lasiocarpine metabolite results in decreased expression of TNFSF10 mRNA CTD PMID:30465738 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of TOP2A mRNA CTD PMID:33884520 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of TOPBP1 mRNA CTD PMID:33884520 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674
JBrowse link
G Tp73 tumor protein p73 increases expression ISO lasiocarpine results in increased expression of TP73 mRNA CTD PMID:32234424 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128
JBrowse link
G Trip13 thyroid hormone receptor interactor 13 increases expression ISO lasiocarpine results in increased expression of TRIP13 mRNA CTD PMID:32234424 NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases expression ISO lasiocarpine results in increased expression of TRPA1 mRNA CTD PMID:32234424 NCBI chr 5:4,379,999...4,433,243
Ensembl chr 5:4,379,999...4,433,570
JBrowse link
G Tspan15 tetraspanin 15 increases expression ISO lasiocarpine results in increased expression of TSPAN15 mRNA CTD PMID:32234424 NCBI chr20:30,130,528...30,174,912
Ensembl chr20:30,130,530...30,174,930
JBrowse link
G Tymp thymidine phosphorylase increases expression ISO lasiocarpine metabolite results in increased expression of TYMP mRNA CTD PMID:30465738 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,125...120,447,429
Ensembl chr 7:120,438,125...120,447,429
JBrowse link
G Tyrp1 tyrosinase-related protein 1 decreases expression ISO lasiocarpine results in decreased expression of TYRP1 mRNA CTD PMID:32234424 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP lasiocarpine results in increased expression of UGT2B17 mRNA CTD PMID:32419051 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 increases expression ISO lasiocarpine results in increased expression of UHRF1 mRNA CTD PMID:32234424 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631
JBrowse link
G Vwf von Willebrand factor decreases expression ISO lasiocarpine metabolite results in decreased expression of VWF mRNA CTD PMID:30465738 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase multiple interactions ISO [CYP3A4 protein results in increased metabolism of lasiocarpine] which results in decreased expression of WEE1 mRNA CTD PMID:33884520 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
G Wnt7b Wnt family member 7B increases expression ISO lasiocarpine results in increased expression of WNT7B mRNA CTD PMID:32234424 NCBI chr 7:116,634,817...116,679,089
Ensembl chr 7:116,634,814...116,679,581
JBrowse link
G Wwox WW domain-containing oxidoreductase decreases expression ISO lasiocarpine results in decreased expression of WWOX mRNA CTD PMID:32234424 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
JBrowse link
otosenine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2ax H2A.X variant histone increases expression ISO otosenine results in increased expression of H2AX protein CTD PMID:31154085 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
riddelliine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP riddelliine results in increased expression of ABCB1 mRNA; riddelliine results in increased expression of ABCB1A mRNA CTD PMID:18047722 PMID:18047727 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 decreases expression EXP riddelliine results in decreased expression of ABCB9 mRNA CTD PMID:18047722 NCBI chr12:32,499,225...32,531,932
Ensembl chr12:32,499,225...32,531,931
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP riddelliine results in increased expression of ABCC3 mRNA CTD PMID:18047722 PMID:18047727 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 decreases expression EXP riddelliine results in decreased expression of ABCC8 mRNA CTD PMID:18047722 PMID:18047727 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 decreases expression EXP riddelliine results in decreased expression of ABCC9 mRNA CTD PMID:18047727 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Adm adrenomedullin decreases expression EXP riddelliine results in decreased expression of ADM mRNA CTD PMID:18047727 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression EXP riddelliine results in increased expression of AHR mRNA CTD PMID:18047727 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Anapc1 anaphase promoting complex subunit 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ANAPC1 mRNA CTD PMID:33884520 NCBI chr 3:115,850,117...115,930,259
Ensembl chr 3:115,850,185...115,930,273
JBrowse link
G Arid2 AT-rich interaction domain 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ARID2 mRNA CTD PMID:33884520 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512
JBrowse link
G Atp13a5 ATPase 13A5 decreases expression EXP riddelliine results in decreased expression of ATP13A5 mRNA CTD PMID:18047722 NCBI chr11:71,376,388...71,515,789
Ensembl chr11:71,376,422...71,515,789
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of AURKA mRNA CTD PMID:33884520 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Babam2 BRISC and BRCA1 A complex member 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of BABAM2 mRNA CTD PMID:33884520 NCBI chr 6:24,369,021...24,833,335
Ensembl chr 6:24,369,022...24,833,951
JBrowse link
G Bard1 BRCA1 associated RING domain 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BARD1 mRNA CTD PMID:33884520 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265
JBrowse link
G Blm BLM RecQ like helicase multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BLM mRNA CTD PMID:33884520 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Bora bora, aurora kinase A activator multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BORA mRNA CTD PMID:33884520 NCBI chr15:75,797,624...75,835,599
Ensembl chr15:75,797,891...75,821,322
JBrowse link
G Brca1 BRCA1, DNA repair associated multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA1 mRNA CTD PMID:33884520 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA2 mRNA CTD PMID:33884520 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brip1 BRCA1 interacting helicase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRIP1 mRNA CTD PMID:33884520 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CCNB1 mRNA CTD PMID:33884520 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CCNB2 mRNA CTD PMID:33884520 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC20 mRNA CTD PMID:33884520 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc23 cell division cycle 23 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC23 mRNA CTD PMID:33884520 NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
JBrowse link
G Cdc25a cell division cycle 25A multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25A mRNA CTD PMID:33884520 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc25b cell division cycle 25B multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25B mRNA CTD PMID:33884520 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25C mRNA CTD PMID:33884520 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK1 mRNA CTD PMID:33884520 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK2 mRNA CTD PMID:33884520 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of CDKN1A mRNA CTD PMID:33884520 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP riddelliine results in increased expression of CES2 mRNA CTD PMID:18047722 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CHEK1 mRNA CTD PMID:33884520 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link
G Clspn claspin multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CLSPN mRNA CTD PMID:33884520 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression EXP riddelliine results in increased expression of CXCR1 mRNA CTD PMID:18047727 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression EXP riddelliine results in increased expression of CYP26A1 mRNA CTD PMID:18047727 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression EXP riddelliine results in decreased expression of CYP2C mRNA CTD PMID:18047722 PMID:18047727 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 increases expression EXP riddelliine results in increased expression of CYP2C12 mRNA CTD PMID:18047727 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 decreases expression EXP riddelliine results in decreased expression of CYP2C13 mRNA CTD PMID:18047727 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 decreases expression EXP riddelliine results in decreased expression of CYP2C22 mRNA CTD PMID:18047727 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP riddelliine results in increased expression of CYP2E1 mRNA CTD PMID:18047722 PMID:18047727 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 decreases expression EXP riddelliine results in decreased expression of CYP3A18 mRNA CTD PMID:18047727 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
multiple interactions
increases metabolic processing
EXP
ISO
riddelliine results in decreased expression of CYP3A2 mRNA
[CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ANAPC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ARID2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ATRIP mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of AURKA mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BARD1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BLM mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BORA mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRCA2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of BRIP1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CCNB1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CCNB2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC20 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC23 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25B mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDC25C mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CDK2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CHEK1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of CLSPN mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F5 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F8 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ESPL1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCA mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCB mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCC mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCD2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FBXO5 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of KIF11 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of KIF23 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MDC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MRE11 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MSH2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MSH6 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of NBN mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PBRM1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PHF10 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PKMYT1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PLK1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PLK4 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of POU2F1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPM1L mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPP2R1B mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPP2R2A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PRC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PTTG1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RAD1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RAD21 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBBP8 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBL1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBL2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC3 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC4 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC5 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RPA1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of SMARCC1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of SMC3 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of STAG2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TLK1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TOP2A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TOPBP1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of WEE1 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of BABAM2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of CDKN1A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of GADD45A mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PLK2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PLK3 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PPP2CB mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of SMARCA2 mRNA; [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of STAT1 mRNA
CTD PMID:18047727 PMID:33884520 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression EXP riddelliine results in increased expression of CYP3A9 mRNA CTD PMID:18047727 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 decreases expression EXP riddelliine results in decreased expression of CYP4A8 mRNA CTD PMID:18047727 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F1 mRNA CTD PMID:33884520 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G E2f5 E2F transcription factor 5 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F5 mRNA CTD PMID:33884520 NCBI chr 2:86,997,331...87,012,901
Ensembl chr 2:86,997,332...87,012,990
JBrowse link
G E2f8 E2F transcription factor 8 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of E2F8 mRNA CTD PMID:33884520 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098
JBrowse link
G Egr1 early growth response 1 increases expression EXP riddelliine results in increased expression of EGR1 mRNA CTD PMID:18047727 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP riddelliine results in decreased expression of ENPP2 mRNA CTD PMID:18047727 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of ESPL1 mRNA CTD PMID:33884520 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G F11r F11 receptor decreases expression EXP riddelliine results in decreased expression of F11R mRNA CTD PMID:18047727 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression EXP riddelliine results in decreased expression of F3 mRNA CTD PMID:18047727 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G F7 coagulation factor VII increases expression EXP riddelliine results in increased expression of F7 mRNA CTD PMID:18047727 NCBI chr16:76,489,779...76,500,636
Ensembl chr16:76,489,717...76,500,610
JBrowse link
G Fanca FA complementation group A multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCA mRNA CTD PMID:33884520 NCBI chr19:51,304,021...51,362,586
Ensembl chr19:51,304,021...51,362,527
JBrowse link
G Fancb FA complementation group B multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCB mRNA CTD PMID:33884520 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Fancc FA complementation group C multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCC mRNA CTD PMID:33884520 NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376
JBrowse link
G Fancd2 FA complementation group D2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FANCD2 mRNA CTD PMID:33884520 NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP riddelliine results in increased expression of FAS mRNA CTD PMID:18047727 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fbxo5 F-box protein 5 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of FBXO5 mRNA CTD PMID:33884520 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 increases expression EXP riddelliine results in increased expression of FMO5 mRNA CTD PMID:18047722 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of GADD45A mRNA CTD PMID:33884520 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP riddelliine results in increased expression of GSTA3 mRNA CTD PMID:18047722 PMID:18047727 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP riddelliine results in decreased expression of GSTM1 mRNA CTD PMID:18047727 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP riddelliine results in decreased expression of GSTM2 mRNA CTD PMID:18047727 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation
increases expression
EXP
ISO
riddelliine results in increased phosphorylation of H2AX protein
riddelliine results in increased expression of H2AX protein
CTD PMID:31154085 PMID:31289892 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hgf hepatocyte growth factor increases expression EXP riddelliine results in increased expression of HGF mRNA CTD PMID:18047727 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP riddelliine results in increased expression of IGFBP1 mRNA CTD PMID:18047727 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression EXP riddelliine results in increased expression of IGFBP2 mRNA CTD PMID:18047727 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Il11 interleukin 11 increases expression EXP riddelliine results in increased expression of IL11 mRNA CTD PMID:18047727 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
JBrowse link
G Il15 interleukin 15 increases expression EXP riddelliine results in increased expression of IL15 mRNA CTD PMID:18047727 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il7 interleukin 7 decreases expression EXP riddelliine results in decreased expression of IL7 mRNA CTD PMID:18047727 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Inmt indolethylamine N-methyltransferase decreases expression EXP riddelliine results in decreased expression of INMT mRNA CTD PMID:18047722 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Itga4 integrin subunit alpha 4 increases expression EXP riddelliine results in increased expression of ITGA4 mRNA CTD PMID:18047727 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
JBrowse link
G Itga6 integrin subunit alpha 6 decreases expression EXP riddelliine results in decreased expression of ITGA6 mRNA CTD PMID:18047727 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428
JBrowse link
G Kdr kinase insert domain receptor multiple interactions
increases expression
EXP riddelliine results in increased phosphorylation of and results in increased activity of KDR protein
riddelliine results in increased expression of KDR protein
CTD PMID:12460743 PMID:15384251 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Kif11 kinesin family member 11 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of KIF11 mRNA CTD PMID:33884520 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif23 kinesin family member 23 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of KIF23 mRNA CTD PMID:33884520 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases mutagenesis ISO riddelliine results in increased mutagenesis of KRAS gene CTD PMID:13678655 PMID:20737008 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Lepr leptin receptor increases expression EXP riddelliine results in increased expression of LEPR mRNA CTD PMID:18047727 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MDC1 mRNA CTD PMID:33884520 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression EXP riddelliine results in decreased expression of MMP7 mRNA CTD PMID:18047727 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MRE11 mRNA CTD PMID:33884520 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279
JBrowse link
G Msh2 mutS homolog 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MSH2 mRNA CTD PMID:33884520 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Msh6 mutS homolog 6 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of MSH6 mRNA CTD PMID:33884520 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Mt1 metallothionein 1 increases expression EXP riddelliine results in increased expression of MT1A mRNA CTD PMID:18047727 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression EXP riddelliine results in decreased expression of MTHFD2 mRNA CTD PMID:18047727 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Nbn nibrin multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of NBN mRNA CTD PMID:33884520 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP riddelliine results in increased expression of NQO1 mRNA CTD PMID:18047722 PMID:18047727 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pbrm1 polybromo 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PBRM1 mRNA CTD PMID:33884520 NCBI chr16:6,213,507...6,312,895
Ensembl chr16:6,213,300...6,311,780
JBrowse link
G Phf10 PHD finger protein 10 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PHF10 mRNA CTD PMID:33884520 NCBI chr 1:55,952,249...55,968,994
Ensembl chr 1:55,952,253...55,969,038
JBrowse link
G Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PKMYT1 mRNA CTD PMID:33884520 NCBI chr10:12,748,221...12,758,995
Ensembl chr10:12,748,237...12,758,995
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PLK1 mRNA CTD PMID:33884520 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk2 polo-like kinase 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PLK2 mRNA CTD PMID:33884520 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Plk3 polo-like kinase 3 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PLK3 mRNA CTD PMID:33884520 NCBI chr 5:130,607,142...130,612,317
Ensembl chr 5:130,607,142...130,612,317
JBrowse link
G Plk4 polo-like kinase 4 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PLK4 mRNA CTD PMID:33884520 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
G Pou2f1 POU class 2 homeobox 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of POU2F1 mRNA CTD PMID:33884520 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression EXP riddelliine results in decreased expression of PPARG mRNA CTD PMID:18047727 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppm1l protein phosphatase, Mg2+/Mn2+ dependent, 1L multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPM1L mRNA CTD PMID:33884520 NCBI chr 2:153,566,653...153,839,434
Ensembl chr 2:153,566,653...153,839,434
JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of PPP2CB mRNA CTD PMID:33884520 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPP2R1B mRNA CTD PMID:33884520 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PPP2R2A mRNA CTD PMID:33884520 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924
JBrowse link
G Prc1 protein regulator of cytokinesis 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PRC1 mRNA CTD PMID:33884520 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prkca protein kinase C, alpha increases expression EXP riddelliine results in increased expression of PRKCA mRNA CTD PMID:18047727 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP riddelliine results in increased expression of PRKCZ mRNA CTD PMID:18047727 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of PTTG1 mRNA CTD PMID:33884520 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rad1 RAD1 checkpoint DNA exonuclease multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RAD1 mRNA CTD PMID:33884520 NCBI chr 2:59,461,597...59,469,707
Ensembl chr 2:59,461,607...59,469,689
JBrowse link
G Rad21 RAD21 cohesin complex component multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RAD21 mRNA CTD PMID:33884520 NCBI chr 7:83,287,867...83,314,810
Ensembl chr 7:83,287,870...83,314,817
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBBP8 mRNA CTD PMID:33884520 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBL1 mRNA CTD PMID:33884520 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RBL2 mRNA CTD PMID:33884520 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Ren renin increases expression EXP riddelliine results in increased expression of REN mRNA CTD PMID:18047727 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rfc1 replication factor C subunit 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC1 mRNA CTD PMID:33884520 NCBI chr14:42,966,279...43,041,372
Ensembl chr14:42,966,324...43,041,370
JBrowse link
G Rfc2 replication factor C subunit 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC2 mRNA CTD PMID:33884520 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557
JBrowse link
G Rfc3 replication factor C subunit 3 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC3 mRNA CTD PMID:33884520 NCBI chr12:1,000,987...1,011,778
Ensembl chr12:1,000,994...1,011,778
JBrowse link
G Rfc4 replication factor C subunit 4 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC4 mRNA CTD PMID:33884520 NCBI chr11:77,749,642...77,764,123
Ensembl chr11:77,749,638...77,764,122
JBrowse link
G Rfc5 replication factor C subunit 5 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RFC5 mRNA CTD PMID:33884520 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
G Rpa1 replication protein A1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of RPA1 mRNA CTD PMID:33884520 NCBI chr10:60,148,869...60,199,999
Ensembl chr10:60,148,793...60,199,949
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 decreases expression EXP riddelliine results in decreased expression of S1PR2 mRNA CTD PMID:18047727 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574
JBrowse link
G Slc13a5 solute carrier family 13 member 5 decreases expression EXP riddelliine results in decreased expression of SLC13A5 mRNA CTD PMID:18047722 NCBI chr10:56,866,249...56,891,189
Ensembl chr10:56,866,249...56,890,945
JBrowse link
G Slc16a4 solute carrier family 16, member 4 decreases expression EXP riddelliine results in decreased expression of SLC16A4 mRNA CTD PMID:18047722 NCBI chr 2:194,911,075...194,933,162
Ensembl chr 2:194,911,236...194,933,117
JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases expression EXP riddelliine results in decreased expression of SLC22A6 mRNA CTD PMID:18047722 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases expression EXP riddelliine results in decreased expression of SLC22A8 mRNA CTD PMID:18047722 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc25a21 solute carrier family 25 member 21 increases expression EXP riddelliine results in increased expression of SLC25A21 mRNA CTD PMID:18047722 NCBI chr 6:74,203,439...74,702,902
Ensembl chr 6:74,203,440...74,702,680
JBrowse link
G Slc25a30 solute carrier family 25, member 30 decreases expression EXP riddelliine results in decreased expression of SLC25A30 mRNA CTD PMID:18047722 NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression EXP riddelliine results in increased expression of SLC7A5 mRNA CTD PMID:18047727 NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
JBrowse link
G Smarca2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of SMARCA2 mRNA CTD PMID:33884520 NCBI chr 1:224,191,125...224,358,640
Ensembl chr 1:224,191,125...224,358,684
JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of SMARCC1 mRNA CTD PMID:33884520 NCBI chr 8:110,111,097...110,214,727
Ensembl chr 8:110,111,122...110,214,720
JBrowse link
G Smc3 structural maintenance of chromosomes 3 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of SMC3 mRNA CTD PMID:33884520 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase increases expression EXP riddelliine results in increased expression of SRC mRNA CTD PMID:18047727 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Stag2 stromal antigen 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of STAG2 mRNA CTD PMID:33884520 NCBI chr  X:120,974,687...121,105,677
Ensembl chr  X:120,974,857...121,105,677
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in increased expression of STAT1 mRNA CTD PMID:33884520 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 decreases expression EXP riddelliine results in decreased expression of SULT1C1 mRNA CTD PMID:18047722 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
G Tgfa transforming growth factor alpha decreases expression EXP riddelliine results in decreased expression of TGFA mRNA CTD PMID:18047727 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
JBrowse link
G Tlk1 tousled-like kinase 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TLK1 mRNA CTD PMID:33884520 NCBI chr 3:55,520,559...55,627,580
Ensembl chr 3:55,503,358...55,691,968
JBrowse link
G Tnf tumor necrosis factor decreases expression EXP riddelliine results in decreased expression of TNF mRNA CTD PMID:18047727 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression EXP riddelliine results in increased expression of TNFSF10 mRNA CTD PMID:18047727 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TOP2A mRNA CTD PMID:33884520 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of TOPBP1 mRNA CTD PMID:33884520 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674
JBrowse link
G Tp53 tumor protein p53 increases expression
increases mutagenesis
EXP
ISO
riddelliine results in increased expression of TP53 protein
riddelliine results in increased mutagenesis of TRP53 gene
CTD PMID:12460743 PMID:13678655 PMID:20737008 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase multiple interactions ISO [CYP3A4 protein results in increased metabolism of riddelliine] which results in decreased expression of WEE1 mRNA CTD PMID:33884520 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
senecionine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO senecionine results in decreased expression of ABCB11 mRNA CTD PMID:26100227 PMID:31606820 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression ISO senecionine results in decreased expression of ABCB1 mRNA CTD PMID:31606820 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP senecionine results in increased expression of ABCB1B mRNA CTD PMID:32419051 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases expression ISO senecionine results in decreased expression of ABCB4 mRNA CTD PMID:31606820 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO senecionine results in increased expression of ABCC1 mRNA CTD PMID:31606820 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases expression ISO senecionine results in decreased expression of ABCC2 mRNA CTD PMID:26100227 PMID:31606820 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
EXP
ISO
senecionine results in increased expression of ABCC3 mRNA
senecionine results in decreased expression of ABCC3 mRNA
CTD PMID:24641316 PMID:26100227 PMID:31606820 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO senecionine results in decreased expression of ABCC4 mRNA CTD PMID:31606820 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO senecionine results in decreased expression of ABCC6 mRNA CTD PMID:26100227 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO senecionine results in decreased expression of ACSL3 mRNA CTD PMID:26100227 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acsm3 acyl-CoA synthetase medium-chain family member 3 decreases expression ISO senecionine results in decreased expression of ACSM3 mRNA CTD PMID:26100227 NCBI chr 1:174,133,260...174,159,966
Ensembl chr 1:174,133,288...174,160,184
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP senecionine results in decreased expression of ACTG2 mRNA CTD PMID:34185104 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
JBrowse link
G Adam8 ADAM metallopeptidase domain 8 increases expression EXP senecionine results in increased expression of ADAM8 mRNA CTD PMID:32419051 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
JBrowse link
G Aff3 AF4/FMR2 family, member 3 decreases expression ISO senecionine results in decreased expression of AFF3 mRNA CTD PMID:26100227 NCBI chr 9:40,399,109...40,856,716
Ensembl chr 9:40,404,375...40,857,247
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase decreases expression ISO senecionine results in decreased expression of AGXT mRNA CTD PMID:26100227 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP senecionine results in increased expression of ALDH1A1 mRNA CTD PMID:32419051 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression ISO senecionine results in increased expression of ALDH6A1 mRNA CTD PMID:26100227 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldh8a1 aldehyde dehydrogenase 8 family, member A1 decreases expression ISO senecionine results in decreased expression of ALDH8A1 mRNA CTD PMID:26100227 NCBI chr 1:16,183,940...16,203,385
Ensembl chr 1:16,183,940...16,203,385
JBrowse link
G Ankrd1 ankyrin repeat domain 1 decreases expression EXP senecionine results in decreased expression of ANKRD1 mRNA CTD PMID:34185104 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Areg amphiregulin increases expression ISO senecionine results in increased expression of AREG mRNA CTD PMID:26100227 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A increases expression EXP senecionine results in increased expression of ARHGAP11A mRNA CTD PMID:32419051 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 increases expression EXP senecionine results in increased expression of ATAD2 mRNA CTD PMID:32419051 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
JBrowse link
G Axin2 axin 2 decreases expression ISO senecionine results in decreased expression of AXIN2 mRNA CTD PMID:31606820 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression EXP
ISO
senecionine results in decreased expression of BAAT mRNA CTD PMID:24641316 PMID:26100227 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO senecionine results in decreased expression of BCL2L1 protein CTD PMID:29458164 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G C3ar1 complement C3a receptor 1 increases expression EXP senecionine results in increased expression of C3AR1 mRNA CTD PMID:34185104 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Casp12 caspase 12 increases expression EXP senecionine results in increased expression of CASP12 mRNA CTD PMID:32419051 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions ISO senecionine results in increased activity of and results in increased cleavage of CASP3 protein CTD PMID:29458164 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO senecionine results in increased activity of and results in increased cleavage of CASP8 protein CTD PMID:29458164 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity ISO senecionine results in increased activity of CASP9 protein CTD PMID:29458164 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Ccna2 cyclin A2 increases expression EXP senecionine results in increased expression of CCNA2 mRNA CTD PMID:32419051 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccne2 cyclin E2 increases expression EXP senecionine results in increased expression of CCNE2 mRNA CTD PMID:32419051 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccng1 cyclin G1 increases expression EXP senecionine results in increased expression of CCNG1 mRNA CTD PMID:32419051 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP senecionine results in increased expression of CDKN1A mRNA CTD PMID:32419051 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cenpq centromere protein Q increases expression EXP senecionine results in increased expression of CENPQ mRNA CTD PMID:32419051 NCBI chr 9:19,957,040...19,972,807
Ensembl chr 9:19,957,048...19,972,789
JBrowse link
G Cenpw centromere protein W increases expression EXP senecionine results in increased expression of CENPW mRNA CTD PMID:32419051 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
JBrowse link
G Ckap2 cytoskeleton associated protein 2 increases expression EXP senecionine results in increased expression of CKAP2 mRNA CTD PMID:32419051 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 decreases expression EXP senecionine results in decreased expression of CKMT2 mRNA CTD PMID:34185104 NCBI chr 2:23,079,920...23,110,518
Ensembl chr 2:23,079,918...23,110,430
JBrowse link
G Clec4a3 C-type lectin domain family 4, member A3 increases expression EXP senecionine results in increased expression of CLEC4A1 mRNA CTD PMID:34185104 NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817
JBrowse link
G Clec4f C-type lectin domain family 4, member F decreases expression EXP senecionine results in decreased expression of CLEC4F mRNA CTD PMID:32419051 NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
JBrowse link
G Csf1r colony stimulating factor 1 receptor decreases expression EXP senecionine results in decreased expression of CSF1R mRNA CTD PMID:32419051 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP11A1 mRNA CTD PMID:26100227 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP1A1 mRNA CTD PMID:26100227 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
decreases expression
ISO senecionine results in increased expression of CYP1A2 mRNA
senecionine results in decreased expression of CYP1A2 mRNA
CTD PMID:26100227 PMID:31606820 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP1B1 mRNA CTD PMID:26100227 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 increases expression ISO senecionine results in increased expression of CYP2A13 mRNA CTD PMID:26100227 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 affects expression ISO senecionine affects the expression of CYP2B10 mRNA CTD PMID:31606820 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO senecionine results in increased expression of CYP2B6 mRNA CTD PMID:26100227 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 decreases expression ISO senecionine results in decreased expression of CYP2C18 mRNA CTD PMID:26100227 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
decreases expression
ISO senecionine results in increased expression of CYP2E1 mRNA
senecionine results in decreased expression of CYP2E1 mRNA
CTD PMID:26100227 PMID:31606820 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression ISO senecionine results in increased expression of CYP3A43 mRNA CTD PMID:26100227 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO senecionine results in increased expression of CYP3A4 mRNA CTD PMID:26100227 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases expression ISO senecionine results in decreased expression of CYP3A5 mRNA CTD PMID:26100227 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 decreases expression ISO senecionine results in decreased expression of CYP4F12 mRNA CTD PMID:26100227 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
JBrowse link
G Cyp4f40 cytochrome P450, family 4, subfamily f, polypeptide 40 increases expression ISO senecionine results in increased expression of CYP4F11 mRNA CTD PMID:26100227 NCBI chr 7:11,691,648...11,707,437
Ensembl chr 7:11,692,086...11,706,229
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G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP
ISO
senecionine results in decreased expression of CYP7A1 mRNA CTD PMID:24641316 PMID:26100227 PMID:31606820 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 decreases expression ISO senecionine results in decreased expression of CYP8B1 mRNA CTD PMID:26100227 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G