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ONTOLOGY REPORT - ANNOTATIONS


Term:benzophenanthridine alkaloid
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Accession:CHEBI:38517 term browser browse the term
Definition:A specific group of isoquinoline alkaloids that occur only in higher plants and are constituents mainly of the Papaveraceae family.
Synonyms:related_synonym: benzophenanthridine alkaloids


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chelerythrine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp6 caspase 6 JBrowse link 2 235,341,326 235,353,715 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Casr calcium-sensing receptor JBrowse link 11 67,188,204 67,262,261 RGD:6480464
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:6480464
G Cftr CF transmembrane conductance regulator JBrowse link 4 42,693,263 42,860,679 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Edn1 endothelin 1 JBrowse link 17 22,136,814 22,143,745 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6480464
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:6480464
G Kcnd3 potassium voltage-gated channel subfamily D member 3 JBrowse link 2 207,923,775 208,140,727 RGD:6480464
G Lmna lamin A/C JBrowse link 2 187,842,884 187,863,552 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Nppa natriuretic peptide A JBrowse link 5 164,808,407 164,809,716 RGD:6480464
G Nts neurotensin JBrowse link 7 44,111,594 44,120,998 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:6480464
G Prkce protein kinase C, epsilon JBrowse link 6 9,483,400 9,973,396 RGD:6480464
G Ptges3 prostaglandin E synthase 3 JBrowse link 7 2,479,267 2,497,024 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Slc1a1 solute carrier family 1 member 1 JBrowse link 1 246,955,017 247,035,159 RGD:6480464
G Slc5a6 solute carrier family 5 member 6 JBrowse link 6 26,685,823 26,697,110 RGD:6480464
G Sptan1 spectrin, alpha, non-erythrocytic 1 JBrowse link 3 8,534,437 8,599,259 RGD:6480464
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464
G Tjp1 tight junction protein 1 JBrowse link 1 126,146,489 126,515,359 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:6480464
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:6480464
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:6480464
chelidonine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Dapk1 death associated protein kinase 1 JBrowse link 17 4,297,038 4,454,941 RGD:6480464
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:6480464
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:6480464
dihydrosanguinarine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
sanguinarine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Arnt aryl hydrocarbon receptor nuclear translocator JBrowse link 2 196,594,178 196,651,486 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bbc3 Bcl-2 binding component 3 JBrowse link 1 78,261,491 78,267,802 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l14 BCL2 like 14 JBrowse link 4 168,139,964 168,183,726 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:6480464
G Bik BCL2-interacting killer JBrowse link 7 124,390,924 124,410,449 RGD:6480464
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:6480464
G Bnip3l BCL2 interacting protein 3 like JBrowse link 15 43,643,897 43,667,123 RGD:6480464
G Card6 caspase recruitment domain family, member 6 JBrowse link 2 54,810,676 54,824,050 RGD:6480464
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp4 caspase 4 JBrowse link 8 2,616,391 2,651,682 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cldn2 claudin 2 JBrowse link X 111,122,552 111,133,188 RGD:6480464
G Cldn3 claudin 3 JBrowse link 12 21,831,341 21,832,813 RGD:6480464
G Cldn4 claudin 4 JBrowse link 12 24,761,210 24,763,008 RGD:6480464
G Cldn5 claudin 5 JBrowse link 11 86,356,292 86,357,718 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Dedd2 death effector domain containing 2 JBrowse link 1 82,073,024 82,089,028 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hal histidine ammonia lyase JBrowse link 7 34,326,087 34,356,413 RGD:6480464
G Hpgds hematopoietic prostaglandin D synthase JBrowse link 4 95,945,356 95,970,666 RGD:6480464
G Ltb lymphotoxin beta JBrowse link 20 5,184,631 5,186,476 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Nfkbiz NFKB inhibitor zeta JBrowse link 11 47,243,342 47,271,487 RGD:6480464
G Nlrp1a NLR family, pyrin domain containing 1A JBrowse link 10 57,692,474 57,747,608 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:6480464
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:6480464
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:6480464
G Tnfsf10 TNF superfamily member 10 JBrowse link 2 113,008,008 113,026,899 RGD:6480464
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        biochemical role 19147
          metabolite 19115
            alkaloid 5269
              isoquinoline alkaloid 1125
                benzophenanthridine alkaloid 96
                  (+/-)-6-Acetonyldihydrochelerythrine 0
                  (+/-)-6-Acetonyldihydrosanguinarine 0
                  (+/-)-Bocconarborine A 0
                  (+/-)-Bocconarborine B 0
                  (+/-)-Homochelidonine 0
                  10-hydroxydihydrochelirubine 0
                  10-hydroxydihydrosanguinarine 0
                  12-hydroxydihydrochelirubine 0
                  6-(2-Hydroxyethyl)-5,6-dihydrosanguinarine 0
                  6-Oxochelerythrine 0
                  Angoline 0
                  Chelilutine 0
                  Decarine 0
                  Fagaridine 0
                  Hydroxysanguinarine 0
                  N-Methyl-2,3,7,8-tetramethoxy-5,6-dihydrobenzophenathridine-6-ethanoic acid 0
                  N-methyl-2,3,7,8-tetramethoxybenzophenanthridine-6(5H)-one 0
                  Norchelerythrine 0
                  Sanguilutine 0
                  Sanguirubine 0
                  chelerythrine 50
                  chelidonine + 8
                  chelirubine + 0
                  corynoline 0
                  dihydrochelerythrine 0
                  dihydrochelirubine 0
                  dihydromacarpine 0
                  dihydrosanguinarine + 3
                  fagaronine 0
                  macarpine 0
                  sanguinarine + 51
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic molecule 19353
                              organic cyclic compound 19102
                                organic heterocyclic compound 18170
                                  organonitrogen heterocyclic compound 16978
                                    benzophenanthridine 119
                                      benzophenanthridine alkaloid 96
                                        (+/-)-6-Acetonyldihydrochelerythrine 0
                                        (+/-)-6-Acetonyldihydrosanguinarine 0
                                        (+/-)-Bocconarborine A 0
                                        (+/-)-Bocconarborine B 0
                                        (+/-)-Homochelidonine 0
                                        10-hydroxydihydrochelirubine 0
                                        10-hydroxydihydrosanguinarine 0
                                        12-hydroxydihydrochelirubine 0
                                        6-(2-Hydroxyethyl)-5,6-dihydrosanguinarine 0
                                        6-Oxochelerythrine 0
                                        Angoline 0
                                        Chelilutine 0
                                        Decarine 0
                                        Fagaridine 0
                                        Hydroxysanguinarine 0
                                        N-Methyl-2,3,7,8-tetramethoxy-5,6-dihydrobenzophenathridine-6-ethanoic acid 0
                                        N-methyl-2,3,7,8-tetramethoxybenzophenanthridine-6(5H)-one 0
                                        Norchelerythrine 0
                                        Sanguilutine 0
                                        Sanguirubine 0
                                        chelerythrine 50
                                        chelidonine + 8
                                        chelirubine + 0
                                        corynoline 0
                                        dihydrochelerythrine 0
                                        dihydrochelirubine 0
                                        dihydromacarpine 0
                                        dihydrosanguinarine + 3
                                        fagaronine 0
                                        macarpine 0
                                        sanguinarine + 51
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.