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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:steroid alkaloid fundamental parent
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Accession:CHEBI:38516 term browser browse the term
Synonyms:related_synonym: steroid alkaloid fundamental parents


show annotations for term's descendants           Sort by:
solanidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO solanidine results in decreased activity of BCHE protein CTD PMID:31152736 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
tomatidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO tomatidine results in decreased activity of BCHE protein CTD PMID:31152736 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 decreases phosphorylation ISO tomatidine results in decreased phosphorylation of MAPK1 protein CTD PMID:23566884 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases phosphorylation ISO tomatidine results in decreased phosphorylation of MAPK3 protein CTD PMID:23566884 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions		 ISO tomatidine results in decreased expression of MMP2 mRNA; tomatidine results in decreased expression of MMP2 protein
tomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein modified form]		 CTD PMID:23566884 PMID:31545954 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
multiple interactions		 ISO tomatidine results in decreased expression of MMP9 mRNA; tomatidine results in decreased expression of MMP9 protein
tomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]		 CTD PMID:23566884 PMID:31545954 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression ISO tomatidine results in increased expression of RECK mRNA CTD PMID:23566884 NCBI chr 4:43,875,521...43,944,806
Ensembl chr 4:43,875,530...43,944,806 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) decreases expression ISO tomatidine results in decreased expression of RELA protein CTD PMID:23566884 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression ISO tomatidine results in increased expression of TIMP1 mRNA CTD PMID:23566884 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974 		JBrowse link
veratridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain derived neurotrophic factor multiple interactions
increases expression		 EXP
ISO		 cypermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]; Permethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]
Tetrodotoxin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]		 CTD PMID:11082455 PMID:16166269 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352 		JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha multiple interactions
increases secretion		 ISO nociceptin (1-13) amide inhibits the reaction [Veratridine results in increased secretion of CALCA protein] CTD PMID:17640294 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592 		JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression		 EXP
ISO		 cypermethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA]; Permethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA] CTD PMID:11082455 PMID:19463813 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047 		JBrowse link
G Grm5 glutamate receptor, metabotropic 5 multiple interactions ISO [6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Veratridine results in increased secretion of Dopamine] CTD PMID:12907309 NCBI chr 7:87,233,212...87,784,271
Ensembl chr 7:87,233,376...87,784,115 		JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression		 ISO Tetrodotoxin inhibits the reaction [Veratridine results in increased expression of NPY mRNA] CTD PMID:2233698 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    chemical entity 22208
      atom 22170
        nonmetal atom 22055
          carbon atom 21859
            organic molecular entity 21830
              organic fundamental parent 20308
                natural product fundamental parent 15190
                  alkaloid fundamental parent 2875
                    steroid alkaloid fundamental parent 13
                      cevane + 5
                      conanine + 0
                      samandarine 0
                      solanidine + 1
                      spirosolane + 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    main group molecular entity 22104
                      s-block molecular entity 21729
                        hydrogen molecular entity 21646
                          hydrides 20758
                            organic hydride 20308
                              organic fundamental parent 20308
                                natural product fundamental parent 15190
                                  alkaloid fundamental parent 2875
                                    steroid alkaloid fundamental parent 13
                                      cevane + 5
                                      conanine + 0
                                      samandarine 0
                                      solanidine + 1
                                      spirosolane + 8
paths to the root