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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor
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Accession:CHEBI:38503 term browser browse the term
Definition:A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H(+)-translocating), EC 1.6.5.3.
Synonyms:related_synonym: Coenzyme Q reductase;   DPNH-coenzyme Q reductase inhibitor;   DPNH-ubiquinone reductase inhibitor;   EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitors;   EC 1.6.5.3 inhibitor;   EC 1.6.5.3 inhibitors;   NADH coenzyme Q1 reductase inhibitor;   NADH coenzyme Q1 reductase inhibitors;   NADH dehydrogenase (ubiquinone) inhibitor;   NADH dehydrogenase (ubiquinone) inhibitors;   NADH-CoQ oxidoreductase inhibitor;   NADH-CoQ oxidoreductase inhibitors;   NADH-CoQ reductase inhibitor;   NADH-CoQ reductase inhibitors;   NADH-Q6 oxidoreductase inhibitor;   NADH-coenzyme Q oxidoreductase inhibitors;   NADH-coenzyme Q reductase inhibitor;   NADH-coenzyme Q reductase inhibitors;   NADH-ubiquinone oxidoreductase inhibitors;   NADH-ubiquinone reductase inhibitors;   NADH-ubiquinone-1 reductase inhibitor;   NADH-ubiquinone-1 reductase inhibitors;   NADH2 dehydrogenase (ubiquinone) inhibitor;   NADH:ubiquinone oxidoreductase complex inhibitor;   NADH:ubiquinone oxidoreductase inhibitor;   NADH:ubiquinone reductase (H(+)-translocating) inhibitors;   NADH:ubiquinone reductase (H+-translocating) inhibitor;   NADH:ubiquinone reductase inhibitor;   complex 1 dehydrogenase inhibitor;   complex I (NADH:Q1 oxidoreductase) inhibitors;   complex I (electron transport chain) inhibitors;   dihydronicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor;   electron transfer complex I inhibitor;   electron transfer complex I inhibitors;   mitochondrial electron transport complex 1 inhibitor;   mitochondrial electron transport complex I inhibitor;   mitochondrial electron transport complex I inhibitors;   reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitor;   reduced nicotinamide adenine dinucleotide-coenzyme Q reductase inhibitors;   type 1 dehydrogenase inhibitor;   type 1 dehydrogenase inhibitors;   ubiquinone reductase inhibitor;   ubiquinone reductase inhibitors
 xref: Wikipedia:NADH_dehydrogenase_(ubiquinone)


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  CHEBI ontology 19816
    role 19764
      biological role 19764
        inhibitor 18247
          enzyme inhibitor 18173
            pathway inhibitor 8896
              electron-transport chain inhibitor 4801
                respiratory-chain inhibitor 3685
                  EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor 3344
                    (2S)-6-(gamma,gamma-dimethylallyl)-3',4'-dimethoxy-6'',6''-dimethylpyran[2'',3'':7,8]flavanone 0
                    (2S)-6-(gamma,gamma-dimethylallyl)-5,3'-dihydroxy-4'-methoxy-6'',6''-dimethylpyran[2'',3'':7,8]flavanone 0
                    (2S)-6-(gamma,gamma-dimethylallyl)-5,4'-dihydroxy-3'-methoxy-6'',6''-dimethylpyran[2'',3'':7,8]flavanone 0
                    (2S)-6-(gamma,gamma-dimethylallyl)-5-hydroxy-3',4'-dimethoxy-6'',6''-dimethylpyran[2'',3'':7,8]flavanone 0
                    atovaquone 3
                    aureothin 0
                    mitochondrial NADH:ubiquinone reductase inhibitor + 3341
                    piericidin A 1
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