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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:carbosulfan
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Accession:CHEBI:38476 term browser browse the term
Definition:A 1-benzofuran that has formula C20H32N2O3S.
Synonyms:exact_synonym: 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl [(dibutylamino)sulfanyl](methyl)carbamate
 related_synonym: Dibutylaminosulfenylcarbofuran;   Formula=C20H32N2O3S;   InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3;   InChIKey=JLQUFIHWVLZVTJ-UHFFFAOYSA-N;   SMILES=CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12
 xref: Beilstein:1397995;   CAS:55285-14-8;   KEGG:C18416
 xref_mesh: MESH:C035038
 xref: PPDB:121


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carbosulfan term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity EXP carbosulfan results in decreased activity of ACHE protein CTD PMID:3710030 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases activity
increases expression
increases metabolic processing
ISO carbosulfan results in increased activity of CYP2B6 protein
carbosulfan results in increased expression of CYP2B6 mRNA
CYP2B6 protein results in increased metabolism of carbosulfan
CTD PMID:20307514, PMID:22310298 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing ISO CYP3A5 protein results in increased metabolism of carbosulfan CTD PMID:20307514 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression ISO carbosulfan results in increased expression of NR1I3 mRNA CTD PMID:22310298 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        agrochemical 14435
          carbosulfan 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic ester 14073
                                        carbamate ester 7378
                                          carbosulfan 4
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