Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tebufenozide
go back to main search page
Accession:CHEBI:38452 term browser browse the term
Definition:A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.
Synonyms:exact_synonym: N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide
 related_synonym: 3,5-dimethylbenzoic acid 1-(1,1-dimethylethyl)-2-(4-ethylbenzoyl)hydrazide;   Formula=C22H28N2O2;   InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25);   InChIKey=QYPNKSZPJQQLRK-UHFFFAOYSA-N;   N'-(t-butyl)-N'-(3,5-dimethylbenzoyl)-N-(4-ethylbenzoyl)hydrazine;   SMILES=CCc1ccc(cc1)C(=O)NN(C(=O)c1cc(C)cc(C)c1)C(C)(C)C
 xref: Beilstein:7822297;   CAS:112410-23-8;   KEGG:C18526
 xref_mesh: MESH:C082026
 xref: PMID:14745824;   PMID:15759403;   PMID:22730139;   PMID:24121094;   PPDB:611;   Patent:CN103553255;   Patent:CN103766364;   Pesticides:tebufenozide;   Reaxys:7822297;   Wikipedia:Tebufenozide



show annotations for term's descendants           Sort by:
tebufenozide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases transport
ISO tebufenozide inhibits the reaction [ABCB1 protein results in increased transport of Quinidine]
ABCB1 protein results in increased transport of tebufenozide
CTD PMID:26995013 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO tebufenozide results in increased expression of CYP2B6 mRNA CTD PMID:22310298 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO tebufenozide results in increased expression of CYP3A4 mRNA CTD PMID:22310298 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Rorb RAR-related orphan receptor B increases activity ISO tebufenozide results in increased activity of RORB protein CTD PMID:20143881 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      biological role 19892
        xenobiotic 18778
          tebufenozide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        aromatic carboxylic acid 12279
                                          benzoic acids 12254
                                            benzoic acid 5331
                                              benzohydrazide 5
                                                1,2-dibenzoylhydrazine 4
                                                  N'-benzoyl-N-(tert-butyl)benzohydrazide 4
                                                    tebufenozide 4
paths to the root