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ONTOLOGY REPORT - ANNOTATIONS


Term:(2E,4E)-hexa-2,4-dienoic acid
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Accession:CHEBI:38358 term browser browse the term
Definition:A sorbic acid having trans-double bonds at positions 2 and 4; a food preservative that can induce cutaneous vasodilation and stinging upon topical application to humans. It is the most thermodynamically stable of the four possible geometric isomers possible, as well as the one with the highest antimicrobial activity.
Synonyms:related_synonym: (2E,4E)-2,4-hexadienoic acid;   (E,E)-1,3-pentadiene-1-carboxylic acid;   (E,E)-2,4-hexadienoic acid;   (E,E)-SA;   (E,E)-sorbic acid;   1,3-pentadiene-1-carboxylic acid;   Formula=C6H8O2;   InChI=1S/C6H8O2/c1-2-3-4-5-6(7)8/h2-5H,1H3,(H,7,8)/b3-2+,5-4+;   InChIKey=WSWCOQWTEOXDQX-MQQKCMAXSA-N;   SA;   SMILES=C\\C=C\\C=C\\C(O)=O;   alpha-trans-gamma-trans-sorbic acid;   trans,trans-2,4-hexadienoic acid;   trans,trans-SA;   trans,trans-sorbic acid
 xref: Beilstein:1098547 "Beilstein";   CAS:110-44-1 "ChemIDplus";   CAS:110-44-1 "NIST Chemistry WebBook";   Gmelin:260824 "Gmelin";   Gmelin:3063 "Gmelin";   LIPID_MAPS_instance:LMFA01030100 "LIPID MAPS"
 xref_mesh: MESH:D013011
 xref: PMID:11206806 "Europe PMC";   PMID:7979442 "Europe PMC"
 cyclic_relationship: is_conjugate_acid_of CHEBI:77869


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(2E,4E)-hexa-2,4-dienoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOSL1 FOS like 1, AP-1 transcription factor subunit JBrowse link 11 65,892,049 65,900,526 RGD:6480464
G ORM1 orosomucoid 1 JBrowse link 9 114,323,023 114,326,479 RGD:6480464
G PHEX phosphate regulating endopeptidase homolog X-linked JBrowse link X 22,032,325 22,251,310 RGD:6480464
G RAD51AP1 RAD51 associated protein 1 JBrowse link 12 4,538,890 4,560,047 RGD:6480464
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23699
    chemical entity 23660
      atom 23646
        nonmetal atom 23290
          carbon atom 23143
            organic molecular entity 23143
              lipid 19517
                fatty acid 18118
                  medium-chain fatty acid 2837
                    sorbic acid 5
                      (2E,4E)-hexa-2,4-dienoic acid 5
                        nigragillin 0
                        trans,trans-2,4-hexadienoyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23699
    subatomic particle 23646
      composite particle 23646
        hadron 23646
          baryon 23646
            nucleon 23646
              atomic nucleus 23646
                atom 23646
                  main group element atom 23465
                    p-block element atom 23465
                      carbon group element atom 23166
                        carbon atom 23143
                          organic molecular entity 23143
                            organic group 21827
                              organic divalent group 21797
                                organodiyl group 21797
                                  carbonyl group 21768
                                    carbonyl compound 21768
                                      carboxylic acid 20796
                                        monocarboxylic acid 19765
                                          fatty acid 18118
                                            unsaturated fatty acid 916
                                              polyunsaturated fatty acid 668
                                                hexadienoic acid 5
                                                  sorbic acid 5
                                                    (2E,4E)-hexa-2,4-dienoic acid 5
                                                      nigragillin 0
                                                      trans,trans-2,4-hexadienoyl-CoA 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.