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G |
NPHS1 |
NPHS1 adhesion molecule, nephrin |
multiple interactions |
ISO |
Mycophenolate mofetil inhibits reaction [streptozotocin decreases expression of Nphs1 mRNA and protein in kidney] |
RGD |
PMID:17624267 |
RGD:38596322 |
NCBI chr19:35,862,915...35,869,357
Ensembl chr19:35,825,964...35,869,287
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G |
ABCF1 |
ATP binding cassette subfamily F member 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of ABCF1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 6:30,571,442...30,591,522
Ensembl chr 6:30,571,393...30,597,179
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G |
ADM |
adrenomedullin |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased expression of ADM protein] |
CTD |
PMID:15063164 |
|
NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
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G |
AGT |
angiotensinogen |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of AGT protein alternative form |
CTD |
PMID:15213268 |
|
NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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G |
AIF1 |
allograft inflammatory factor 1 |
decreases expression multiple interactions |
ISO |
Mycophenolic Acid results in decreased expression of AIF1 mRNA [Quercetin co-treated with Mycophenolic Acid] results in decreased expression of AIF1 mRNA |
CTD |
PMID:10688038 |
|
NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
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G |
AIMP1 |
aminoacyl tRNA synthetase complex interacting multifunctional protein 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of AIMP1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 4:106,315,544...106,349,456
Ensembl chr 4:106,315,544...106,349,456
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G |
AKT1 |
AKT serine/threonine kinase 1 |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of AKT1 protein |
CTD |
PMID:21396949 |
|
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
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G |
ALB |
albumin |
affects binding |
EXP |
Mycophenolic Acid binds to ALB protein |
CTD |
PMID:26892221 |
|
NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482
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G |
AR |
androgen receptor |
multiple interactions |
EXP |
Mycophenolic Acid binds to and results in decreased activity of AR protein |
CTD |
PMID:25752796 |
|
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
|
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G |
ATF1 |
activating transcription factor 1 |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of ATF1 protein] |
CTD |
PMID:20302854 |
|
NCBI chr12:50,763,459...50,821,162
Ensembl chr12:50,763,710...50,821,162
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G |
BAK1 |
BCL2 antagonist/killer 1 |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of BAK1 protein |
CTD |
PMID:16505121 |
|
NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
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|
G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
[Mycophenolic Acid co-treated with Hypoxanthine] results in increased expression of BAX protein |
CTD |
PMID:21396949 |
|
NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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|
G |
BCL2 |
BCL2 apoptosis regulator |
multiple interactions decreases expression |
EXP |
[Mycophenolic Acid co-treated with Hypoxanthine] results in decreased expression of BCL2 protein; Mycophenolic Acid inhibits the reaction [BCL2 protein results in decreased susceptibility to Dexamethasone]; schizandrin A inhibits the reaction [Mycophenolic Acid results in decreased expression of BCL2 protein] |
CTD |
PMID:16505121 PMID:21396949 PMID:35321622 |
|
NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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|
G |
CASP1 |
caspase 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CASP1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
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G |
CASP3 |
caspase 3 |
increases activity increases cleavage multiple interactions |
EXP |
Mycophenolic Acid results in increased activity of CASP3 protein Mycophenolic Acid results in increased cleavage of CASP3 protein [Mycophenolic Acid co-treated with Hypoxanthine] results in increased activity of CASP3 protein; schizandrin A inhibits the reaction [Mycophenolic Acid results in increased cleavage of CASP3 protein] |
CTD |
PMID:16059982 PMID:16505121 PMID:21396949 PMID:35321622 |
|
NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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|
G |
CCL15 |
C-C motif chemokine ligand 15 |
decreases expression increases expression |
ISO |
Mycophenolic Acid results in decreased expression of CCL6 mRNA Mycophenolic Acid results in increased expression of CCL6 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553
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G |
CCL19 |
C-C motif chemokine ligand 19 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCL19 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 9:34,689,570...34,691,276
Ensembl chr 9:34,689,570...34,691,276
|
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G |
CCL2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 protein] |
CTD |
PMID:17624267 |
|
NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208
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G |
CCL20 |
C-C motif chemokine ligand 20 |
decreases expression increases expression |
ISO |
Mycophenolic Acid results in decreased expression of CCL20 mRNA Mycophenolic Acid results in increased expression of CCL20 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 2:227,813,842...227,817,556
Ensembl chr 2:227,805,739...227,817,564
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G |
CCL22 |
C-C motif chemokine ligand 22 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCL22 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr16:57,357,909...57,366,189
Ensembl chr16:57,358,783...57,366,189
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G |
CCL25 |
C-C motif chemokine ligand 25 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCL25 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr19:8,052,341...8,062,650
Ensembl chr19:8,052,318...8,062,660
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G |
CCL4 |
C-C motif chemokine ligand 4 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of CCL4 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
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G |
CCL5 |
C-C motif chemokine ligand 5 |
multiple interactions decreases expression |
ISO |
[Quercetin co-treated with Mycophenolic Acid] results in decreased expression of CCL5 mRNA Mycophenolic Acid results in decreased expression of CCL5 mRNA |
CTD |
PMID:10688038 |
|
NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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G |
CCL7 |
C-C motif chemokine ligand 7 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of CCL7 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr17:34,270,221...34,272,242
Ensembl chr17:34,270,221...34,272,242
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G |
CCR10 |
C-C motif chemokine receptor 10 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR10 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr17:42,678,889...42,681,843
Ensembl chr17:42,678,889...42,683,917
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G |
CCR2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR2 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
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G |
CCR3 |
C-C motif chemokine receptor 3 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR3 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706
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G |
CCR6 |
C-C motif chemokine receptor 6 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR6 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 6:167,111,795...167,139,141
Ensembl chr 6:167,111,807...167,139,141
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G |
CCR9 |
C-C motif chemokine receptor 9 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR9 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 3:45,886,064...45,903,174
Ensembl chr 3:45,884,425...45,903,174
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G |
CD40LG |
CD40 ligand |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CD40LG mRNA |
CTD |
PMID:19818335 |
|
NCBI chr X:136,648,158...136,660,390
Ensembl chr X:136,648,158...136,660,390
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G |
CDKN1B |
cyclin dependent kinase inhibitor 1B |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [IL2 protein results in decreased expression of CDKN1B protein] |
CTD |
PMID:12193749 |
|
NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369
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|
G |
CREB1 |
cAMP responsive element binding protein 1 |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:20302854 |
|
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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G |
CX3CL1 |
C-X3-C motif chemokine ligand 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CX3CL1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044
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G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
decreases expression increases expression |
ISO |
Mycophenolic Acid results in decreased expression of CXCL1 mRNA Mycophenolic Acid results in increased expression of CXCL1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
|
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G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCL12 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
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G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCL2 protein |
CTD |
PMID:19818335 |
|
NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
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G |
CXCL8 |
C-X-C motif chemokine ligand 8 |
increases expression decreases expression increases secretion multiple interactions |
ISO EXP |
Mycophenolic Acid results in increased expression of CXCL15 mRNA; Mycophenolic Acid results in increased expression of CXCL5 mRNA Mycophenolic Acid results in decreased expression of CXCL5 mRNA Mycophenolic Acid results in increased secretion of CXCL8 protein Mycophenolic Acid results in increased expression of CXCL8 mRNA Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased secretion of CXCL8 protein] |
CTD |
PMID:19818335 PMID:20302854 PMID:29408666 PMID:29594315 |
|
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
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G |
CXCR2 |
C-X-C motif chemokine receptor 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCR2 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
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|
G |
CXCR3 |
C-X-C motif chemokine receptor 3 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCR3 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr X:71,615,919...71,618,511
Ensembl chr X:71,615,916...71,618,511
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G |
CXCR5 |
C-X-C motif chemokine receptor 5 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCR5 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr11:118,883,892...118,897,787
Ensembl chr11:118,883,892...118,897,787
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G |
CYCS |
cytochrome c, somatic |
increases secretion |
EXP |
Mycophenolic Acid results in increased secretion of CYCS protein |
CTD |
PMID:16505121 |
|
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
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G |
CYP1A1 |
cytochrome P450 family 1 subfamily A member 1 |
increases expression multiple interactions |
EXP |
Mycophenolic Acid results in increased expression of CYP1A1 mRNA Mycophenolic Acid affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mycophenolic Acid promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Mycophenolic Acid promotes the reaction [Esomeprazole results in increased expression of CYP1A1 mRNA]; Mycophenolic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:25929522 |
|
NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
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G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
multiple interactions |
EXP |
Mycophenolic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:25929522 |
|
NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
|
|
G |
CYP2C8 |
cytochrome P450 family 2 subfamily C member 8 |
increases methylation |
EXP |
CYP2C8 protein results in increased methylation of Mycophenolic Acid |
CTD |
PMID:15570183 |
|
NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497
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G |
CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
increases methylation multiple interactions |
EXP |
CYP3A4 protein results in increased methylation of Mycophenolic Acid [Mycophenolic Acid results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA |
CTD |
PMID:15570183 PMID:25455453 |
|
NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
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G |
CYP3A5 |
cytochrome P450 family 3 subfamily A member 5 |
increases methylation |
EXP |
CYP3A5 protein results in increased methylation of Mycophenolic Acid |
CTD |
PMID:15570183 |
|
NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996
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G |
DES |
desmin |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein] |
CTD |
PMID:17624267 |
|
NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735
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G |
ESR1 |
estrogen receptor 1 |
multiple interactions |
EXP |
Mycophenolic Acid binds to and results in decreased activity of ESR1 protein |
CTD |
PMID:25752796 |
|
NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
|
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G |
ESR2 |
estrogen receptor 2 |
multiple interactions |
EXP |
Mycophenolic Acid binds to and results in decreased activity of ESR2 protein |
CTD |
PMID:25752796 |
|
NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
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G |
FAM200C |
family with sequence similarity 200 member C |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of FAM200C mRNA |
CTD |
PMID:24356939 |
|
NCBI chr 5:160,393,148...160,400,054
Ensembl chr 5:160,393,148...160,400,054
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of FOS mRNA |
CTD |
PMID:12730611 |
|
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
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G |
GCNA |
germ cell nuclear acidic peptidase |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of GCNA mRNA |
CTD |
PMID:24356939 |
|
NCBI chr X:71,578,437...71,613,583
Ensembl chr X:71,578,437...71,613,583
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G |
GSK3B |
glycogen synthase kinase 3 beta |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:20302854 |
|
NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of HSPA5 mRNA |
CTD |
PMID:24356939 |
|
NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
IFNG |
interferon gamma |
decreases expression multiple interactions |
ISO EXP |
Mycophenolic Acid results in decreased expression of IFNG mRNA [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA |
CTD |
PMID:11562063 PMID:29594315 |
|
NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
IL10 |
interleukin 10 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of IL10 mRNA |
CTD |
PMID:11562063 |
|
NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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G |
IL10RA |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL10RA mRNA |
CTD |
PMID:19818335 |
|
NCBI chr11:117,986,394...118,003,037
Ensembl chr11:117,986,370...118,003,037
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G |
IL10RB |
interleukin 10 receptor subunit beta |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL10RB mRNA |
CTD |
PMID:19818335 |
|
NCBI chr21:33,266,367...33,310,182
Ensembl chr21:33,266,367...33,311,420
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|
G |
IL11 |
interleukin 11 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL11 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463
|
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G |
IL12RB2 |
interleukin 12 receptor subunit beta 2 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of IL12RB2 mRNA |
CTD |
PMID:11562063 |
|
NCBI chr 1:67,307,364...67,398,724
Ensembl chr 1:67,307,364...67,398,724
|
|
G |
IL13 |
interleukin 13 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL13 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
|
|
G |
IL15 |
interleukin 15 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL15 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
|
|
G |
IL16 |
interleukin 16 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL16 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr15:81,182,712...81,314,058
Ensembl chr15:81,159,575...81,314,058
|
|
G |
IL18 |
interleukin 18 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of IL18 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
|
|
G |
IL1R1 |
interleukin 1 receptor type 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL1R1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 2:102,070,390...102,179,874
Ensembl chr 2:102,064,544...102,179,874
|
|
G |
IL1R2 |
interleukin 1 receptor type 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL1R2 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544
|
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G |
IL2 |
interleukin 2 |
multiple interactions decreases expression |
EXP ISO |
[Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Mycophenolic Acid inhibits the reaction [IL2 protein results in decreased expression of CDKN1B protein] Mycophenolic Acid results in decreased expression of IL2 mRNA |
CTD |
PMID:11562063 PMID:12193749 PMID:29594315 |
|
NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725
|
|
G |
IL2RB |
interleukin 2 receptor subunit beta |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL2RB mRNA |
CTD |
PMID:19818335 |
|
NCBI chr22:37,125,838...37,175,118
Ensembl chr22:37,118,666...37,175,118
|
|
G |
IL2RG |
interleukin 2 receptor subunit gamma |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL2RG mRNA |
CTD |
PMID:19818335 |
|
NCBI chr X:71,107,404...71,111,577
Ensembl chr X:71,107,404...71,112,108
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G |
IL3 |
interleukin 3 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL3 mRNA |
CTD |
PMID:19818335 |
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NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
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IL4 |
interleukin 4 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of IL4 mRNA |
CTD |
PMID:11562063 |
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NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
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IL5RA |
interleukin 5 receptor subunit alpha |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL5RA mRNA |
CTD |
PMID:19818335 |
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NCBI chr 3:3,066,324...3,110,374
Ensembl chr 3:3,066,324...3,126,613
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IL6 |
interleukin 6 |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of IL6 protein |
CTD |
PMID:11981085 |
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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IL6R |
interleukin 6 receptor |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL6RA mRNA |
CTD |
PMID:19818335 |
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NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450
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IL6ST |
interleukin 6 cytokine family signal transducer |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL6ST mRNA |
CTD |
PMID:19818335 |
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NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
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IMPDH2 |
inosine monophosphate dehydrogenase 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IMPDH2 mRNA |
CTD |
PMID:11145582 |
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NCBI chr 3:49,024,325...49,029,398
Ensembl chr 3:49,024,325...49,029,447
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ITGAM |
integrin subunit alpha M |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of ITGAM mRNA |
CTD |
PMID:19818335 |
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NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
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KLRK1 |
killer cell lectin like receptor K1 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of KLRK1 |
CTD |
PMID:20736080 |
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NCBI chr12:10,372,353...10,390,041
Ensembl chr12:10,372,353...10,391,874
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KRCC1 |
lysine rich coiled-coil 1 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of KRCC1 mRNA |
CTD |
PMID:24356939 |
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NCBI chr 2:88,027,205...88,055,783
Ensembl chr 2:88,027,205...88,064,252
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LRRC37A3 |
leucine rich repeat containing 37 member A3 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of LRRC37A3 mRNA |
CTD |
PMID:24356939 |
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NCBI chr17:64,854,130...64,919,478
Ensembl chr17:64,854,130...64,919,480
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LTA |
lymphotoxin alpha |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of LTA mRNA |
CTD |
PMID:19818335 |
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NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324
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LTB |
lymphotoxin beta |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of LTB mRNA |
CTD |
PMID:19818335 |
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NCBI chr 6:31,580,558...31,582,425
Ensembl chr 6:31,580,525...31,582,522
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LYN |
LYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
EXP |
[Mycophenolic Acid co-treated with Imatinib Mesylate] results in decreased phosphorylation of LYN protein |
CTD |
PMID:15604220 |
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NCBI chr 8:55,879,835...56,014,169
Ensembl chr 8:55,879,835...56,014,169
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MAPK1 |
mitogen-activated protein kinase 1 |
multiple interactions increases phosphorylation decreases expression |
EXP |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; schizandrin A inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of MAPK1 protein] Mycophenolic Acid results in decreased expression of MAPK1 protein modified form |
CTD |
PMID:20302854 PMID:35321622 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions increases phosphorylation decreases expression |
EXP |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; schizandrin A inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of MAPK3 protein] Mycophenolic Acid results in decreased expression of MAPK3 protein modified form |
CTD |
PMID:20302854 PMID:35321622 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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MAPK8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation decreases expression |
EXP ISO |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; schizandrin A inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of MAPK8 protein] Mycophenolic Acid results in decreased expression of MAPK8 protein modified form |
CTD |
PMID:20302854 PMID:35321622 |
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NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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MAPK9 |
mitogen-activated protein kinase 9 |
multiple interactions decreases expression |
EXP ISO |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein] Mycophenolic Acid results in decreased expression of MAPK9 protein modified form |
CTD |
PMID:20302854 |
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NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
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MAPT |
microtubule associated protein tau |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of MAPT protein |
CTD |
PMID:16930453 |
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NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334
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MIF |
macrophage migration inhibitory factor |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of MIF mRNA |
CTD |
PMID:19818335 |
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NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
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NANOS1 |
nanos C2HC-type zinc finger 1 |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of NANOS1 mRNA |
CTD |
PMID:24356939 |
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NCBI chr10:119,029,714...119,033,730
Ensembl chr10:119,029,714...119,033,730
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NCR1 |
natural cytotoxicity triggering receptor 1 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of NCR1 |
CTD |
PMID:20736080 |
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NCBI chr19:54,898,198...54,938,208
Ensembl chr19:54,906,148...54,916,140
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NCR2 |
natural cytotoxicity triggering receptor 2 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of NCR2 |
CTD |
PMID:20736080 |
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NCBI chr 6:41,335,608...41,350,889
Ensembl chr 6:41,335,608...41,350,889
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NCR3 |
natural cytotoxicity triggering receptor 3 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of NCR3 |
CTD |
PMID:20736080 |
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NCBI chr 6:31,588,895...31,593,006
Ensembl chr 6:31,588,895...31,593,006
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NPHS1 |
NPHS1 adhesion molecule, nephrin |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein] |
CTD |
PMID:17624267 |
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NCBI chr19:35,862,915...35,869,357
Ensembl chr19:35,825,964...35,869,287
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NR1I2 |
nuclear receptor subfamily 1 group I member 2 |
increases activity multiple interactions |
EXP |
Mycophenolic Acid results in increased activity of NR1I2 protein [Mycophenolic Acid results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA |
CTD |
PMID:25455453 |
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NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
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OCLN |
occludin |
decreases expression multiple interactions |
EXP |
Mycophenolic Acid results in decreased expression of OCLN protein schizandrin A inhibits the reaction [Mycophenolic Acid results in decreased expression of OCLN protein] |
CTD |
PMID:35321622 |
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NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
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PDCD4 |
programmed cell death 4 |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of PDCD4 mRNA |
CTD |
PMID:24356939 |
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NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006
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PGR |
progesterone receptor |
multiple interactions |
EXP |
Mycophenolic Acid binds to and results in decreased activity of PGR protein |
CTD |
PMID:25752796 |
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NCBI chr11:101,029,624...101,129,813
Ensembl chr11:101,029,624...101,129,813
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PRKCA |
protein kinase C alpha |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of PRKCA protein |
CTD |
PMID:21396949 |
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NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
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RAC1 |
Rac family small GTPase 1 |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [RAC1 protein results in increased abundance of Reactive Oxygen Species] |
CTD |
PMID:17950325 |
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NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
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RELA |
RELA proto-oncogene, NF-kB subunit |
decreases expression multiple interactions |
ISO EXP |
Mycophenolic Acid results in decreased expression of RELA protein modified form Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RELA protein] |
CTD |
PMID:20302854 |
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NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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RGS2 |
regulator of G protein signaling 2 |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of RGS2 mRNA |
CTD |
PMID:24356939 |
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NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275
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RPS6 |
ribosomal protein S6 |
multiple interactions |
EXP |
[Mycophenolic Acid co-treated with Imatinib Mesylate] results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:15604220 |
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NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236
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SLC22A2 |
solute carrier family 22 member 2 |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
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NCBI chr 6:160,216,755...160,258,821
Ensembl chr 6:160,171,061...160,277,638
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SLC7A11 |
solute carrier family 7 member 11 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of SLC7A11 mRNA |
CTD |
PMID:24356939 |
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NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
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SPP1 |
secreted phosphoprotein 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of SPP1 mRNA |
CTD |
PMID:19818335 |
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NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
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STAT5A |
signal transducer and activator of transcription 5A |
multiple interactions |
EXP |
[Mycophenolic Acid co-treated with Imatinib Mesylate] results in decreased phosphorylation of STAT5A protein |
CTD |
PMID:15604220 |
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NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943
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TGFB1 |
transforming growth factor beta 1 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of TGFB1 mRNA |
CTD |
PMID:11562063 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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THRA |
thyroid hormone receptor alpha |
multiple interactions |
EXP |
Mycophenolic Acid binds to and results in decreased activity of THRA protein |
CTD |
PMID:25752796 |
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NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867
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TJP1 |
tight junction protein 1 |
decreases expression multiple interactions |
EXP |
Mycophenolic Acid results in decreased expression of TJP1 protein schizandrin A inhibits the reaction [Mycophenolic Acid results in decreased expression of TJP1 protein] |
CTD |
PMID:35321622 |
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NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
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TNF |
tumor necrosis factor |
decreases expression multiple interactions increases expression |
ISO |
Mycophenolic Acid results in decreased expression of TNF mRNA Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased secretion of TNF protein] Mycophenolic Acid results in increased expression of TNF mRNA; Mycophenolic Acid results in increased expression of TNF protein |
CTD |
PMID:11562063 PMID:11912253 PMID:19818335 |
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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TNFRSF1A |
TNF receptor superfamily member 1A |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of TNFRSF1A mRNA |
CTD |
PMID:19818335 |
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NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114
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TNFRSF1B |
TNF receptor superfamily member 1B |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of TNFRSF1B mRNA |
CTD |
PMID:19818335 |
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NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228
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TP53 |
tumor protein p53 |
affects activity |
EXP |
Mycophenolic Acid affects the activity of TP53 protein |
CTD |
PMID:35435491 |
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
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TSPOAP1 |
TSPO associated protein 1 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of TSPOAP1 mRNA |
CTD |
PMID:24356939 |
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NCBI chr17:58,301,231...58,328,795
Ensembl chr17:58,301,228...58,328,795
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UGT1A9 |
UDP glucuronosyltransferase family 1 member A9 |
increases glucuronidation multiple interactions affects metabolic processing |
EXP |
UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid 4-cresol inhibits the reaction [[UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid] which results in increased abundance of mycophenolic acid glucuronide]; [4-cresol inhibits the reaction [[UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid] which results in increased abundance of mycophenolic acid glucuronide]] which results in increased abundance of Mycophenolic Acid; [UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid] which results in increased abundance of mycophenolic acid glucuronide UGT1A9 gene SNP affects the metabolism of Mycophenolic Acid |
CTD |
PMID:18498916 PMID:18816295 PMID:31742356 |
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NCBI chr 2:233,671,898...233,773,300
Ensembl chr 2:233,671,898...233,773,300
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