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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:thiazolidine
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Accession:CHEBI:38333 term browser browse the term
Definition:A saturated organic heteromonocyclic parent comprising a five-membered ring with a sulfur at position 1 and a nitrogen at either position 2 or 3.
Synonyms:related_synonym: thiazolidines
 xref: PMID:7716788


show annotations for term's descendants           Sort by:
1,3-thiazolidine-2,4-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2-associated X protein increases expression ISO 2,4-thiazolidinedione results in increased expression of BAX protein CTD PMID:15916743 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of BCL2 protein CTD PMID:15916743 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of CCND1 protein CTD PMID:15916743 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdk4 cyclin dependent kinase 4 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of CDK4 protein CTD PMID:15916743 NCBI chr10:126,899,404...126,903,157
Ensembl chr10:126,899,403...126,903,789 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO 2,4-thiazolidinedione results in increased expression of CDKN1A protein CTD PMID:15916743 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Cdkn1b cyclin dependent kinase inhibitor 1B increases expression ISO 2,4-thiazolidinedione results in increased expression of CDKN1B protein CTD PMID:15916743 NCBI chr 6:134,897,364...134,902,488
Ensembl chr 6:134,897,364...134,902,476 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of CYP1A1 mRNA CTD PMID:15521013 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO 2,4-thiazolidinedione results in decreased expression of PCNA protein CTD PMID:15916743 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects binding
multiple interactions
increases expression		 ISO 2,4-thiazolidinedione binds to PPARG protein
2,4-thiazolidinedione binds to and results in increased activity of PPARG protein
2,4-thiazolidinedione results in increased expression of PPARG mRNA		 CTD PMID:15521013 PMID:15916743 PMID:20724125 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360 		JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of RB1 protein CTD PMID:15916743 NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262 		JBrowse link
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 increases expression ISO 2,4-thiazolidinedione results in increased expression of SLC2A4 mRNA CTD PMID:20724125 NCBI chr11:69,833,112...69,839,040
Ensembl chr11:69,833,365...69,839,014 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    chemical entity 22208
      atom 22170
        nonmetal atom 22055
          nitrogen atom 20030
            nitrogen molecular entity 20004
              organonitrogen compound 19809
                organonitrogen heterocyclic compound 19099
                  thiazolidines 8210
                    thiazolidine 11
                      1,2-thiazolidine + 0
                      1,3-thiazolidine + 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            organic molecule 21647
                              organic cyclic compound 21252
                                organic heterocyclic compound 20352
                                  organic heteromonocyclic compound 18733
                                    thiazolidines 8210
                                      thiazolidine 11
                                        1,2-thiazolidine + 0
                                        1,3-thiazolidine + 11
paths to the root