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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:thiazolidine
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Accession:CHEBI:38333 term browser browse the term
Definition:A saturated organic heteromonocyclic parent comprising a five-membered ring with a sulfur at position 1 and a nitrogen at either position 2 or 3.
Synonyms:related_synonym: thiazolidines
 xref: PMID:7716788


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1,3-thiazolidine-2,4-dione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO 2,4-thiazolidinedione results in increased expression of BAX protein CTD PMID:15916743 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO 2,4-thiazolidinedione results in decreased expression of BCL2 protein CTD PMID:15916743 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of CCND1 protein CTD PMID:15916743 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of CDK4 protein CTD PMID:15916743 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 2,4-thiazolidinedione results in increased expression of CDKN1A protein CTD PMID:15916743 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO 2,4-thiazolidinedione results in increased expression of CDKN1B protein CTD PMID:15916743 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of CYP1A1 mRNA CTD PMID:15521013 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO 2,4-thiazolidinedione results in decreased expression of PCNA protein CTD PMID:15916743 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
increases expression
multiple interactions
ISO
EXP
2,4-thiazolidinedione binds to PPARG protein
2,4-thiazolidinedione results in increased expression of PPARG mRNA
2,4-thiazolidinedione binds to and results in increased activity of PPARG protein
CTD PMID:15521013 PMID:15916743 PMID:20724125 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rb1 RB transcriptional corepressor 1 decreases expression ISO 2,4-thiazolidinedione results in decreased expression of RB1 protein CTD PMID:15916743 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression EXP 2,4-thiazolidinedione results in increased expression of SLC2A4 mRNA CTD PMID:20724125 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19853
    chemical entity 19853
      atom 19851
        nonmetal atom 19733
          nitrogen atom 18620
            nitrogen molecular entity 18620
              organonitrogen compound 18395
                organonitrogen heterocyclic compound 17564
                  thiazolidines 3253
                    thiazolidine 11
                      1,2-thiazolidine + 0
                      1,3-thiazolidine + 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19744
                    p-block element atom 19744
                      carbon group element atom 19650
                        carbon atom 19639
                          organic molecular entity 19639
                            organic molecule 19568
                              organic cyclic compound 19378
                                organic heterocyclic compound 18495
                                  organic heteromonocyclic compound 16597
                                    thiazolidines 3253
                                      thiazolidine 11
                                        1,2-thiazolidine + 0
                                        1,3-thiazolidine + 11
paths to the root