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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:diazolidine
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Accession:CHEBI:38304 term browser browse the term
Synonyms:related_synonym: diazolidines


show annotations for term's descendants           Sort by:
4-hydroxyphenytoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO UGT1A1 protein results in increased glucuronidation of and results in decreased activity of hydroxyphenytoin CTD PMID:15855726 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 multiple interactions ISO UGT1A4 protein results in increased glucuronidation of and results in decreased activity of hydroxyphenytoin CTD PMID:15855726 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions ISO UGT1A6 protein results in increased glucuronidation of and results in decreased activity of hydroxyphenytoin CTD PMID:15855726 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 multiple interactions ISO UGT1A9 protein results in increased glucuronidation of and results in decreased activity of hydroxyphenytoin CTD PMID:15855726 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgdr prostaglandin D2 receptor multiple interactions ISO
EXP 		BW 245C binds to and results in increased activity of PTGDR protein; BW 245C inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 PMID:15528449 PMID:20719937 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases response to substance ISO BW 245C results in decreased susceptibility to TGFB1 protein CTD PMID:20719937 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
allantoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin] CTD PMID:24709313 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Il1b interleukin 1 beta increases secretion
decreases secretion 		ISO
EXP 		Allantoin results in increased secretion of IL1B protein
Allantoin results in decreased secretion of IL1B protein 		CTD PMID:30654793 PMID:32382552 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases secretion
decreases secretion 		ISO
EXP 		Allantoin results in increased secretion of IL6 protein
Allantoin results in decreased secretion of IL6 protein 		CTD PMID:30654793 PMID:32382552 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Lepr leptin receptor affects abundance ISO LEPR affects the abundance of Allantoin CTD PMID:20567778 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression
increases expression 		EXP
ISO 		Allantoin results in decreased expression of NOS2 protein
Allantoin results in increased expression of NOS2 protein 		CTD PMID:30654793 PMID:32382552 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP Allantoin results in decreased expression of PTGS2 protein CTD PMID:30654793 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression ISO Allantoin results in increased expression of TGFB1 protein CTD PMID:32382552 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor decreases secretion
increases secretion 		EXP
ISO 		Allantoin results in decreased secretion of TNF protein
Allantoin results in increased secretion of TNF protein 		CTD PMID:30654793 PMID:32382552 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
affects secretion 		ISO
EXP 		Allantoin results in increased expression of VEGFA protein
Allantoin affects the secretion of VEGFA protein 		CTD PMID:30654793 PMID:32382552 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP [2,2,5,7,8-pentamethyl-1-hydroxychroman results in decreased activity of XDH protein] which results in decreased abundance of Allantoin CTD PMID:21920950 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Azimilide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions 		ISO azimilide results in decreased activity of KCNH2 protein
Acids inhibits the reaction [azimilide results in decreased activity of KCNH2 protein]; azimilide promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [azimilide results in decreased activity of KCNH2 protein]; Potassium inhibits the reaction [azimilide results in decreased activity of KCNH2 protein] 		CTD PMID:15821840 PMID:16960444 PMID:18057881 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
BW A868C term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgdr prostaglandin D2 receptor multiple interactions EXP
ISO 		BW A868C binds to and results in decreased activity of PTGDR protein
BW A868C binds to and results in increased activity of PTGDR protein; BW A868C inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] 		CTD PMID:9579725 PMID:15528449 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679 		JBrowse link
creatinine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmal1 basic helix-loop-helix ARNT like 1 increases abundance ISO BMAL1 gene mutant form results in increased abundance of Creatinine CTD PMID:27056296 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; Dexamethasone inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; huang-lien-chieh-tu-tang inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine] CTD PMID:24709313 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance 		ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Creatinine] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Lepr leptin receptor affects abundance
multiple interactions
increases abundance 		ISO LEPR affects the abundance of Creatinine
Glucagon analog inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine]; swietenine inhibits the reaction [LEPR gene mutant form results in increased abundance of Creatinine] 		CTD PMID:20567778 PMID:29988851 PMID:36066211 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [NFE2L2 protein affects the susceptibility to ochratoxin A] which results in increased abundance of Creatinine CTD PMID:28710020 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [SC 560 results in decreased activity of PTGS1 protein] which results in increased abundance of Creatinine CTD PMID:19629487 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Creatinine inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637 		JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Creatinine inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904 		JBrowse link
G Sod2 superoxide dismutase 2 decreases abundance ISO SOD2 protein results in decreased abundance of Creatinine CTD PMID:19917352 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
dantrolene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects transport ISO ABCG2 protein affects the transport of Dantrolene CTD PMID:18322075 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Ace2 angiotensin converting enzyme 2 increases expression ISO Dantrolene results in increased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Atf4 activating transcription factor 4 decreases expression
multiple interactions 		EXP
ISO 		Dantrolene results in decreased expression of ATF4 protein
Dantrolene affects the reaction [perfluorooctanoic acid results in increased expression of ATF4 protein]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein]; Dantrolene promotes the reaction [Thapsigargin results in increased expression of ATF4 mRNA] 		CTD PMID:15921666 PMID:32578922 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of BAX mRNA] CTD PMID:32795494 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Dantrolene results in increased expression of BCL2 protein CTD PMID:10854250 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l11 Bcl2-like 11 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of BCL2L11 mRNA] CTD PMID:32795494 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Dantrolene inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein] CTD PMID:16553631 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Capn1 calpain 1 decreases expression EXP Dantrolene results in decreased expression of CAPN1 mRNA; Dantrolene results in decreased expression of CAPN1 protein CTD PMID:11236903 NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177 		JBrowse link
G Capn2 calpain 2 decreases expression EXP Dantrolene results in decreased expression of CAPN2 mRNA; Dantrolene results in decreased expression of CAPN2 protein CTD PMID:11236903 NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969 		JBrowse link
G Capn3 calpain 3 decreases expression EXP Dantrolene results in decreased expression of CAPN3 mRNA; Dantrolene results in decreased expression of CAPN3 protein CTD PMID:11236903 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO 		Dantrolene inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]
Dantrolene inhibits the reaction [Indomethacin results in increased activity of CASP3 protein] 		CTD PMID:17079870 PMID:23022152 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO Dantrolene inhibits the reaction [Indomethacin results in increased activity of CASP9 protein] CTD PMID:23022152 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Dantrolene results in decreased expression of CCL2 mRNA CTD PMID:25051504 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 affects expression EXP Dantrolene affects the expression of CCL5 protein CTD PMID:25051504 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of CXCL2 mRNA] CTD PMID:32795494 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP 		Dantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Dantrolene inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases phosphorylation
multiple interactions 		EXP
ISO 		Dantrolene results in decreased phosphorylation of DDIT3 protein
Dantrolene inhibits the reaction [Halothane results in increased expression of DDIT3 mRNA]; Dantrolene promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 mRNA]; Dantrolene promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 protein] 		CTD PMID:15921666 PMID:32578922 PMID:32795494 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Edn1 endothelin 1 decreases activity EXP Dantrolene results in decreased activity of EDN1 protein CTD PMID:12628492 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 decreases phosphorylation EXP Dantrolene results in decreased phosphorylation of EIF2AK3 protein CTD PMID:15921666 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha decreases phosphorylation
multiple interactions 		EXP
ISO 		Dantrolene results in decreased phosphorylation of EIF2S1 protein
Dantrolene inhibits the reaction [tributyltin results in increased phosphorylation of EIF2S1 protein] 		CTD PMID:15921666 PMID:23743301 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of FKBP1A mRNA] CTD PMID:32795494 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of FKBP1B mRNA] CTD PMID:32795494 NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of GFAP protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein] CTD PMID:21863293 PMID:21879721 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of GPT protein] CTD PMID:32795494 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of HMOX1 mRNA] CTD PMID:32795494 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of HOMER1 mRNA] CTD PMID:32795494 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO Dantrolene inhibits the reaction [tributyltin results in increased expression of HSPA5 protein] CTD PMID:23743301 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Ifng interferon gamma multiple interactions ISO Dantrolene inhibits the reaction [taurolithocholic acid 3-sulfate results in increased expression of IFNG mRNA] CTD PMID:22517774 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases response to substance ISO Dantrolene results in decreased susceptibility to IGF1 protein CTD PMID:16485066 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 decreases response to substance ISO Dantrolene results in decreased susceptibility to IGF2 protein CTD PMID:16485066 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Il10 interleukin 10 multiple interactions
affects expression 		ISO
EXP 		Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]]
Dantrolene affects the expression of IL10 protein 		CTD PMID:17707769 PMID:25051504 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta affects expression
multiple interactions 		EXP
ISO 		Dantrolene affects the expression of IL1B mRNA
Dantrolene inhibits the reaction [Halothane results in increased expression of IL1B mRNA] 		CTD PMID:25051504 PMID:32795494 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Dantrolene inhibits the reaction [taurolithocholic acid 3-sulfate results in increased expression of IL6 mRNA] CTD PMID:22517774 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Dantrolene results in decreased activity of KCNH2 protein CTD PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions ISO Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium] CTD PMID:17189350 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Lep leptin decreases expression EXP Dantrolene results in decreased expression of LEP protein CTD PMID:25051504 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mef2a myocyte enhancer factor 2a multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2A mRNA]; Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2A protein] CTD PMID:25093688 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948 		JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2C mRNA]; Dantrolene inhibits the reaction [Caffeine results in increased expression of MEF2C protein] CTD PMID:25093688 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of MYH7 mRNA] CTD PMID:25093688 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Nefl neurofilament light chain multiple interactions EXP Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFL protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein] CTD PMID:21863293 PMID:21879721 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nefm neurofilament medium chain multiple interactions EXP Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of NEFM protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21863293 PMID:21879721 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755 		JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of NPPA mRNA] CTD PMID:25093688 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Dantrolene inhibits the reaction [Caffeine results in increased expression of NPPB mRNA] CTD PMID:25093688 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions ISO Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium] CTD PMID:17707769 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions EXP Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of S100A8 mRNA] CTD PMID:32795494 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of S100A9 mRNA] CTD PMID:32795494 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO Dantrolene inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of STAR mRNA] CTD PMID:23183170 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions 		EXP
ISO 		Dantrolene results in decreased expression of TNF protein
Dantrolene inhibits the reaction [Halothane results in increased expression of TNF mRNA] 		CTD PMID:11236903 PMID:32795494 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Dantrolene inhibits the reaction [Halothane results in increased expression of VCAM1 mRNA] CTD PMID:32795494 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vim vimentin multiple interactions EXP Dantrolene inhibits the reaction [diphenylditelluride results in decreased phosphorylation of VIM protein]; Dantrolene inhibits the reaction [diphenylditelluride results in increased phosphorylation of VIM protein] CTD PMID:21863293 PMID:21879721 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Xbp1 X-box binding protein 1 multiple interactions ISO Dantrolene inhibits the reaction [perfluorooctanoic acid results in increased expression of XBP1 mRNA alternative form]; Dantrolene inhibits the reaction [Thapsigargin results in increased expression of XBP1 mRNA alternative form] CTD PMID:32578922 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
enzalutamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase decreases expression ISO enzalutamide results in decreased expression of AADAT mRNA CTD PMID:29581250 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression ISO enzalutamide results in decreased expression of ABCC4 mRNA CTD PMID:29581250 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 decreases expression ISO enzalutamide results in decreased expression of ACSM1 mRNA CTD PMID:29581250 NCBI chr 1:173,985,715...174,020,565
Ensembl chr 1:173,984,672...174,025,495 		JBrowse link
G Adam10 ADAM metallopeptidase domain 10 affects expression ISO enzalutamide affects the expression of ADAM10 mRNA CTD PMID:30940724 NCBI chr 8:71,346,008...71,477,889
Ensembl chr 8:71,345,837...71,477,889 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 affects expression ISO enzalutamide affects the expression of ADAM17 mRNA CTD PMID:30940724 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adprm ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent decreases expression ISO enzalutamide results in decreased expression of ADPRM mRNA CTD PMID:29581250 NCBI chr10:51,732,073...51,744,635
Ensembl chr10:51,731,993...51,744,635 		JBrowse link
G Aff3 ALF transcription elongation factor 3 decreases expression ISO enzalutamide results in decreased expression of AFF3 mRNA CTD PMID:29581250 NCBI chr 9:40,399,099...40,856,716
Ensembl chr 9:40,404,375...40,857,247 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 decreases expression ISO enzalutamide results in decreased expression of ALDH1A3 mRNA CTD PMID:29581250 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Alpk2 alpha-kinase 2 decreases expression ISO enzalutamide results in decreased expression of ALPK2 mRNA CTD PMID:29581250 NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258 		JBrowse link
G Anxa4 annexin A4 affects expression ISO enzalutamide affects the expression of ANXA4 mRNA CTD PMID:30940724 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit affects expression ISO enzalutamide affects the expression of APH1A mRNA CTD PMID:30940724 NCBI chr 2:183,437,676...183,443,113
Ensembl chr 2:183,438,434...183,441,955 		JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit affects expression ISO enzalutamide affects the expression of APH1B mRNA CTD PMID:30940724 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243 		JBrowse link
G App amyloid beta precursor protein affects expression ISO enzalutamide affects the expression of APP mRNA CTD PMID:30940724 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Ar androgen receptor multiple interactions
decreases activity
decreases response to substance
decreases expression 		ISO [enzalutamide co-treated with GSK-2816126] inhibits the reaction [AR protein binds to [EZH2 protein binds to SUZ12 protein binds to EED protein]]; [enzalutamide co-treated with Niclosamide] results in decreased expression of AR protein; [enzalutamide co-treated with NVP-BHG712] results in decreased expression of AR mRNA; [enzalutamide co-treated with NVP-BHG712] results in decreased expression of AR mRNA alternative form; [enzalutamide co-treated with NVP-BHG712] results in decreased expression of AR protein; [enzalutamide co-treated with NVP-BHG712] results in decreased expression of AR protein alternative form; [nirogacestat results in increased susceptibility to enzalutamide] which results in decreased expression of AR protein; enzalutamide binds to and results in decreased localization of and results in decreased activity of AR protein; enzalutamide inhibits the reaction [Dihydrotestosterone affects the localization of AR protein]; enzalutamide inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to MYC enhancer]]; enzalutamide inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]; enzalutamide inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; Niclosamide inhibits the reaction [AR protein alternative form results in decreased susceptibility to enzalutamide]
enzalutamide results in decreased activity of AR protein
AR alternative form results in decreased susceptibility to enzalutamide; AR protein alternative form results in decreased susceptibility to enzalutamide; AR protein results in decreased susceptibility to enzalutamide
enzalutamide results in decreased expression of AR protein; enzalutamide results in decreased expression of AR protein alternative form 		CTD PMID:19359544 PMID:24740322 PMID:24759320 PMID:25908785 PMID:25970160 More... NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression ISO enzalutamide results in decreased expression of AZGP1 mRNA CTD PMID:29581250 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions ISO enzalutamide promotes the reaction [Niclosamide results in decreased expression of BIRC5 protein] CTD PMID:25970160 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B decreases expression ISO enzalutamide results in decreased expression of BMPR1B mRNA CTD PMID:29581250 NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G C13h1orf116 similar to human chromosome 1 open reading frame 116 decreases expression ISO enzalutamide results in decreased expression of C1ORF116 mRNA CTD PMID:29581250 NCBI chr13:42,187,442...42,201,432
Ensembl chr13:42,188,609...42,201,426 		JBrowse link
G Casp3 caspase 3 multiple interactions
decreases expression 		ISO enzalutamide promotes the reaction [NVP-BHG712 results in increased cleavage of CASP3 protein]
enzalutamide results in decreased expression of CASP3 protein 		CTD PMID:32184358 PMID:32805266 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 decreases expression ISO enzalutamide results in decreased expression of CASP8 protein CTD PMID:32805266 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO enzalutamide results in decreased expression of CCNB1 protein CTD PMID:32805266 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cd46 CD46 molecule increases expression ISO enzalutamide results in increased expression of CD46 protein CTD PMID:30185663 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [enzalutamide co-treated with NVP-BHG712] results in decreased expression of CDC25C mRNA; [enzalutamide co-treated with NVP-BHG712] results in decreased expression of CDC25C protein CTD PMID:32184358 NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B affects expression ISO enzalutamide affects the expression of CDKN1B mRNA CTD PMID:30940724 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha affects expression ISO enzalutamide affects the expression of CEBPA mRNA CTD PMID:30940724 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases activity
multiple interactions 		ISO enzalutamide results in decreased activity of CFLAR protein
enzalutamide promotes the reaction [lupeol results in decreased activity of CFLAR protein]; lupeol promotes the reaction [enzalutamide results in decreased activity of CFLAR protein] 		CTD PMID:37777120 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Crebbp CREB binding protein affects expression ISO enzalutamide affects the expression of CREBBP mRNA CTD PMID:30940724 NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crisp3 cysteine-rich secretory protein 3 decreases expression ISO enzalutamide results in decreased expression of CRISP3 mRNA CTD PMID:29581250 NCBI chr 9:20,432,051...20,472,663
Ensembl chr 9:20,450,908...20,472,658 		JBrowse link
G Crym crystallin, mu multiple interactions
decreases expression 		ISO KDM1A protein promotes the reaction [enzalutamide results in decreased expression of CRYM mRNA] CTD PMID:29581250 NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633 		JBrowse link
G Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 decreases expression ISO enzalutamide results in decreased expression of CSGALNACT1 mRNA CTD PMID:29581250 NCBI chr16:20,995,210...21,330,586
Ensembl chr16:21,235,784...21,330,319 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases expression ISO enzalutamide results in decreased expression of DPP4 mRNA CTD PMID:29581250 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dtx2 deltex E3 ubiquitin ligase 2 affects expression ISO enzalutamide affects the expression of DTX2 mRNA CTD PMID:30940724 NCBI chr12:26,279,899...26,319,541
Ensembl chr12:20,643,297...20,682,885 		JBrowse link
G Dtx3 deltex E3 ubiquitin ligase 3 affects expression ISO enzalutamide affects the expression of DTX3 mRNA CTD PMID:30940724 NCBI chr 7:64,898,693...64,904,636
Ensembl chr 7:63,013,371...63,018,522 		JBrowse link
G Dtx4 deltex E3 ubiquitin ligase 4 affects expression ISO enzalutamide affects the expression of DTX4 mRNA CTD PMID:30940724 NCBI chr 1:218,882,391...218,969,837
Ensembl chr 1:209,460,735...209,492,818 		JBrowse link
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 decreases expression ISO enzalutamide results in decreased expression of EDEM3 mRNA CTD PMID:29581250 NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523 		JBrowse link
G Eed embryonic ectoderm development multiple interactions
decreases expression 		ISO [enzalutamide co-treated with GSK-2816126] inhibits the reaction [AR protein binds to [EZH2 protein binds to SUZ12 protein binds to EED protein]]; enzalutamide promotes the reaction [GSK-2816126 results in decreased expression of EED protein]; GSK-2816126 promotes the reaction [enzalutamide results in decreased expression of EED protein] CTD PMID:32805266 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Efcab12 EF-hand calcium binding domain 12 decreases expression ISO enzalutamide results in decreased expression of EFCAB12 mRNA CTD PMID:29581250 NCBI chr 4:148,869,381...148,892,922
Ensembl chr 4:148,869,387...148,890,560 		JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 decreases expression ISO enzalutamide results in decreased expression of ELL2 mRNA CTD PMID:29581250 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781 		JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 decreases expression ISO enzalutamide results in decreased expression of ELOVL7 mRNA CTD PMID:29581250 NCBI chr 2:41,522,695...41,592,021
Ensembl chr 2:39,789,250...39,856,845 		JBrowse link
G Ep300 E1A binding protein p300 affects expression ISO enzalutamide affects the expression of EP300 mRNA CTD PMID:30940724 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Ephb4 EPH receptor B4 affects response to substance
multiple interactions 		ISO EPHB4 protein affects the susceptibility to enzalutamide
enzalutamide promotes the reaction [EPHB4 protein affects the expression of KLK3 protein]; EPHB4 protein affects the reaction [enzalutamide results in decreased cleavage of PARP1 protein] 		CTD PMID:32184358 NCBI chr12:19,326,411...19,351,667
Ensembl chr12:19,326,427...19,351,314 		JBrowse link
G Epn1 Epsin 1 affects expression ISO enzalutamide affects the expression of EPN1 mRNA CTD PMID:30940724 NCBI chr 1:68,742,491...68,760,570
Ensembl chr 1:68,742,789...68,758,874 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression
multiple interactions 		ISO enzalutamide results in decreased expression of EZH2 protein
[enzalutamide co-treated with GSK-2816126] inhibits the reaction [AR protein binds to [EZH2 protein binds to SUZ12 protein binds to EED protein]] 		CTD PMID:32805266 NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions
decreases expression 		ISO [enzalutamide co-treated with NVP-BHG712] results in decreased expression of FKBP5 mRNA; enzalutamide promotes the reaction [NVP-BHG712 results in decreased expression of FKBP5 mRNA]; NVP-BHG712 promotes the reaction [enzalutamide results in decreased expression of FKBP5 mRNA] CTD PMID:32184358 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Foxa1 forkhead box A1 affects expression ISO enzalutamide affects the expression of FOXA1 mRNA CTD PMID:30940724 NCBI chr 6:80,838,380...80,871,195
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 affects expression ISO enzalutamide affects the expression of GALNT11 mRNA CTD PMID:30940724 NCBI chr 4:9,837,629...9,871,141
Ensembl chr 4:9,837,629...9,871,140 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase affects expression ISO enzalutamide affects the expression of GMDS mRNA CTD PMID:30940724 NCBI chr17:32,095,315...32,621,975
Ensembl chr17:32,095,386...32,621,961 		JBrowse link
G Gnmt glycine N-methyltransferase decreases expression ISO enzalutamide results in decreased expression of GNMT mRNA CTD PMID:29581250 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 affects expression ISO enzalutamide affects the expression of GOT1 mRNA CTD PMID:30940724 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 decreases expression ISO enzalutamide results in decreased expression of GREB1 mRNA CTD PMID:29581250 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression ISO enzalutamide affects the expression of HES1 mRNA CTD PMID:30940724 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hnf1b HNF1 homeobox B affects expression ISO enzalutamide affects the expression of HNF1B mRNA CTD PMID:30940724 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Ift172 intraflagellar transport 172 affects expression ISO enzalutamide affects the expression of IFT172 mRNA CTD PMID:30940724 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ift74 intraflagellar transport 74 affects expression ISO enzalutamide affects the expression of IFT74 mRNA CTD PMID:30940724 NCBI chr 5:109,460,372...109,563,839
Ensembl chr 5:109,474,255...109,563,833 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO enzalutamide results in decreased expression of IGF1 mRNA CTD PMID:29581250 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO enzalutamide results in decreased expression of IGF1R mRNA CTD PMID:29581250 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases response to substance 		ISO Niclosamide inhibits the reaction [IL6 protein results in decreased susceptibility to enzalutamide] CTD PMID:25970160 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 decreases expression ISO enzalutamide results in decreased expression of IQGAP2 mRNA CTD PMID:29581250 NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase affects expression ISO enzalutamide affects the expression of ITCH mRNA CTD PMID:30940724 NCBI chr 3:164,102,490...164,193,932
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 affects expression ISO enzalutamide affects the expression of ITGB1BP1 mRNA CTD PMID:30940724 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 affects expression ISO enzalutamide affects the expression of JAG1 mRNA CTD PMID:30940724 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Jag2 jagged canonical Notch ligand 2 affects expression ISO enzalutamide affects the expression of JAG2 mRNA CTD PMID:30940724 NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818 		JBrowse link
G Kat2b lysine acetyltransferase 2B affects expression ISO enzalutamide affects the expression of KAT2B mRNA CTD PMID:30940724 NCBI chr 9:6,799,101...6,903,616
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions ISO KDM1A protein promotes the reaction [enzalutamide results in decreased expression of CRYM mRNA]; KDM1A protein promotes the reaction [enzalutamide results in decreased expression of KLK3 protein]; KDM1A protein promotes the reaction [enzalutamide results in decreased expression of LCP1 mRNA]; KDM1A protein promotes the reaction [enzalutamide results in decreased expression of MAP2 mRNA]; KDM1A protein promotes the reaction [enzalutamide results in decreased expression of MYO1B mRNA]; KDM1A protein promotes the reaction [enzalutamide results in decreased expression of SLC22A3 mRNA]; KDM1A protein promotes the reaction [enzalutamide results in decreased expression of TMCC3 mRNA] CTD PMID:29581250 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO enzalutamide results in decreased expression of KIF5C mRNA CTD PMID:29581250 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 increases expression
decreases expression
multiple interactions 		ISO enzalutamide results in increased expression of KLK3 mRNA
enzalutamide results in decreased expression of KLK3 mRNA; enzalutamide results in decreased expression of KLK3 protein
[enzalutamide co-treated with NVP-BHG712] results in decreased expression of KLK3 mRNA; [enzalutamide co-treated with NVP-BHG712] results in decreased expression of KLK3 protein; [nirogacestat results in increased susceptibility to enzalutamide] which results in decreased expression of KLK3 protein; enzalutamide promotes the reaction [EPHB4 protein affects the expression of KLK3 protein]; enzalutamide promotes the reaction [Niclosamide results in decreased expression of KLK3 protein]; enzalutamide promotes the reaction [NVP-BHG712 results in decreased expression of KLK3 mRNA]; enzalutamide promotes the reaction [NVP-BHG712 results in decreased expression of KLK3 protein]; KDM1A protein promotes the reaction [enzalutamide results in decreased expression of KLK3 protein]; NVP-BHG712 promotes the reaction [enzalutamide results in decreased expression of KLK3 protein] 		CTD PMID:19359544 PMID:23704919 PMID:25970160 PMID:29581250 PMID:30940724 More... NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Krt19 keratin 19 affects expression ISO enzalutamide affects the expression of KRT19 mRNA CTD PMID:30940724 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase decreases expression ISO enzalutamide results in decreased expression of LCK mRNA CTD PMID:29581250 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 multiple interactions
decreases expression 		ISO KDM1A protein promotes the reaction [enzalutamide results in decreased expression of LCP1 mRNA] CTD PMID:29581250 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Maf MAF bZIP transcription factor decreases expression ISO enzalutamide results in decreased expression of MAF mRNA CTD PMID:29581250 NCBI chr19:60,259,200...60,622,145
Ensembl chr19:43,360,342...43,712,365 		JBrowse link
G Maml1 mastermind-like transcriptional coactivator 1 affects expression ISO enzalutamide affects the expression of MAML1 mRNA CTD PMID:30940724 NCBI chr10:34,588,639...34,623,024
Ensembl chr10:34,588,646...34,623,338 		JBrowse link
G Maml3 mastermind-like transcriptional coactivator 3 affects expression ISO enzalutamide affects the expression of MAML3 mRNA CTD PMID:30940724 NCBI chr 2:135,720,431...136,137,829
Ensembl chr 2:135,721,021...136,137,814 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [enzalutamide co-treated with GSK-2816126] results in increased expression of MAP1LC3B protein modified form CTD PMID:32805266 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
decreases expression 		ISO KDM1A protein promotes the reaction [enzalutamide results in decreased expression of MAP2 mRNA] CTD PMID:29581250 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mdk midkine affects expression ISO enzalutamide affects the expression of MDK mRNA CTD PMID:30940724 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Mib1 MIB E3 ubiquitin protein ligase 1 affects expression ISO enzalutamide affects the expression of MIB1 mRNA CTD PMID:30940724 NCBI chr18:2,075,309...2,199,774
Ensembl chr18:1,802,519...1,920,689 		JBrowse link
G Mib2 MIB E3 ubiquitin protein ligase 2 affects expression ISO enzalutamide affects the expression of MIB2 mRNA CTD PMID:30940724 NCBI chr 5:171,526,037...171,542,479
Ensembl chr 5:166,243,776...166,259,650 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO enzalutamide promotes the reaction [NVP-BHG712 results in decreased expression of MKI67 protein] CTD PMID:32184358 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 decreases expression ISO enzalutamide results in decreased expression of MPC2 mRNA CTD PMID:29581250 NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664 		JBrowse link
G Msmb microseminoprotein, beta decreases expression ISO enzalutamide results in decreased expression of MSMB mRNA CTD PMID:33932781 NCBI chr16:7,366,536...7,387,124
Ensembl chr16:7,366,536...7,387,123 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
decreases activity
multiple interactions
affects expression 		ISO enzalutamide results in decreased expression of MYC protein
enzalutamide results in decreased activity of MYC protein
enzalutamide promotes the reaction [lupeol results in decreased activity of MYC protein]; lupeol promotes the reaction [enzalutamide results in decreased activity of MYC protein]
[enzalutamide co-treated with NVP-BHG712] results in decreased expression of MYC protein; enzalutamide inhibits the reaction [Dihydrotestosterone promotes the reaction [AR protein binds to MYC enhancer]]; enzalutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of MYC mRNA]; enzalutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of MYC protein]; enzalutamide promotes the reaction [Niclosamide results in decreased expression of MYC protein]; enzalutamide promotes the reaction [NVP-BHG712 results in decreased expression of MYC protein]
enzalutamide affects the expression of MYC mRNA 		CTD PMID:24759320 PMID:25970160 PMID:30940724 PMID:32184358 PMID:37777120 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myo1b myosin Ib multiple interactions
decreases expression 		ISO KDM1A protein promotes the reaction [enzalutamide results in decreased expression of MYO1B mRNA] CTD PMID:29581250 NCBI chr 9:49,690,043...49,852,373
Ensembl chr 9:49,690,086...49,850,798 		JBrowse link
G Ncstn nicastrin affects expression ISO enzalutamide affects the expression of NCSTN mRNA CTD PMID:30940724 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G Neurl1b neuralized E3 ubiquitin protein ligase 1B affects expression ISO enzalutamide affects the expression of NEURL1B mRNA CTD PMID:30940724 NCBI chr10:17,258,317...17,289,362
Ensembl chr10:16,757,208...16,785,119 		JBrowse link
G Nkap NFKB activating protein affects expression ISO enzalutamide affects the expression of NKAP mRNA CTD PMID:30940724 NCBI chr  X:116,373,031...116,392,677
Ensembl chr  X:116,372,839...116,394,945 		JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression
multiple interactions 		ISO enzalutamide results in decreased expression of NKX3-1 mRNA
enzalutamide promotes the reaction [NVP-BHG712 results in decreased expression of NKX3-1 mRNA]; NVP-BHG712 promotes the reaction [enzalutamide results in decreased expression of NKX3-1 mRNA] 		CTD PMID:29581250 PMID:32184358 NCBI chr15:50,883,661...50,886,253
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nle1 notchless homolog 1 affects expression ISO enzalutamide affects the expression of NLE1 mRNA CTD PMID:30940724 NCBI chr10:67,834,059...67,844,771
Ensembl chr10:67,834,062...67,842,658 		JBrowse link
G Notch1 notch receptor 1 affects response to substance
affects expression
multiple interactions 		ISO NOTCH1 protein affects the susceptibility to enzalutamide
enzalutamide affects the expression of NOTCH1 mRNA
[NOTCH1 protein affects the susceptibility to enzalutamide] which affects the cleavage of PARP1 protein 		CTD PMID:30940724 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 affects expression ISO enzalutamide affects the expression of NOTCH2 mRNA CTD PMID:30940724 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Notch3 notch receptor 3 affects expression ISO enzalutamide affects the expression of NOTCH3 mRNA CTD PMID:30940724 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases cleavage
multiple interactions 		ISO enzalutamide results in decreased cleavage of PARP1 protein
[enzalutamide co-treated with GSK-2816126] results in increased cleavage of PARP1 protein; [nirogacestat results in increased susceptibility to enzalutamide] which results in increased cleavage of PARP1 protein; [NOTCH1 protein affects the susceptibility to enzalutamide] which affects the cleavage of PARP1 protein; enzalutamide promotes the reaction [NVP-BHG712 results in increased cleavage of PARP1 protein]; EPHB4 protein affects the reaction [enzalutamide results in decreased cleavage of PARP1 protein] 		CTD PMID:30940724 PMID:32184358 PMID:32805266 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 affects expression ISO enzalutamide affects the expression of PERP mRNA CTD PMID:30940724 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511 		JBrowse link
G Pla2g5 phospholipase A2, group V decreases expression ISO enzalutamide results in decreased expression of PLA2G5 mRNA CTD PMID:29581250 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [enzalutamide co-treated with NVP-BHG712] results in decreased expression of PLK1 mRNA; [enzalutamide co-treated with NVP-BHG712] results in decreased expression of PLK1 protein; enzalutamide promotes the reaction [NVP-BHG712 results in decreased expression of PLK1 mRNA] CTD PMID:32184358 NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 decreases expression ISO enzalutamide results in decreased expression of PLOD2 mRNA CTD PMID:29581250 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Pofut1 protein O-fucosyltransferase 1 affects expression ISO enzalutamide affects the expression of POFUT1 mRNA CTD PMID:30940724 NCBI chr 3:141,708,618...141,735,558
Ensembl chr 3:141,708,644...141,734,786 		JBrowse link
G Psen1 presenilin 1 affects expression ISO enzalutamide affects the expression of PSEN1 mRNA CTD PMID:30940724 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 affects expression ISO enzalutamide affects the expression of PSEN2 mRNA CTD PMID:30940724 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Psenen presenilin enhancer gamma secretase subunit affects expression ISO enzalutamide affects the expression of PSENEN mRNA CTD PMID:30940724 NCBI chr 1:85,814,905...85,816,654
Ensembl chr 1:85,814,905...85,816,192 		JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO enzalutamide results in decreased expression of PTGER4 mRNA CTD PMID:29581250 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Rbm15 RNA binding motif protein 15 affects expression ISO enzalutamide affects the expression of RBM15 mRNA CTD PMID:30940724 NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region affects expression ISO enzalutamide affects the expression of RBPJ mRNA CTD PMID:30940724 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression ISO enzalutamide results in decreased expression of RGS2 mRNA CTD PMID:29581250 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rhou ras homolog family member U decreases expression ISO enzalutamide results in decreased expression of RHOU mRNA CTD PMID:29581250 NCBI chr19:51,641,476...51,651,249
Ensembl chr19:51,641,227...51,650,552 		JBrowse link
G Rps19 ribosomal protein S19 affects expression ISO enzalutamide affects the expression of RPS19 mRNA CTD PMID:30940724 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
Ensembl chr 7:80,480,951...80,486,508 		JBrowse link
G Rps27a ribosomal protein S27a affects expression ISO enzalutamide affects the expression of RPS27A mRNA CTD PMID:30940724 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 affects expression ISO enzalutamide affects the expression of S1PR3 mRNA CTD PMID:30940724 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505 		JBrowse link
G Sel1l SEL1L adaptor subunit of SYVN1 ubiquitin ligase affects expression ISO enzalutamide affects the expression of SEL1L mRNA CTD PMID:30940724 NCBI chr 6:110,735,450...110,779,695
Ensembl chr 6:110,735,450...110,779,648 		JBrowse link
G Selenop selenoprotein P decreases expression ISO enzalutamide results in decreased expression of SELENOP mRNA CTD PMID:29581250 NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions
decreases expression 		ISO KDM1A protein promotes the reaction [enzalutamide results in decreased expression of SLC22A3 mRNA] CTD PMID:29581250 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Snw1 SNW domain containing 1 affects expression ISO enzalutamide affects the expression of SNW1 mRNA CTD PMID:30940724 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Socs2 suppressor of cytokine signaling 2 decreases expression ISO enzalutamide results in decreased expression of SOCS2 mRNA CTD PMID:29581250 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548 		JBrowse link
G Sox9 SRY-box transcription factor 9 affects expression ISO enzalutamide affects the expression of SOX9 mRNA CTD PMID:30940724 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Spen spen family transcriptional repressor affects expression ISO enzalutamide affects the expression of SPEN mRNA CTD PMID:30940724 NCBI chr 5:153,775,287...153,848,677
Ensembl chr 5:153,776,234...153,848,811 		JBrowse link
G Spock1 sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 decreases expression ISO enzalutamide results in decreased expression of SPOCK1 mRNA CTD PMID:29581250 NCBI chr17:6,741,504...7,221,685
Ensembl chr17:6,742,273...7,224,935 		JBrowse link
G St6galnac1 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 decreases expression ISO enzalutamide results in decreased expression of ST6GALNAC1 mRNA CTD PMID:29581250 NCBI chr10:101,972,656...101,983,053
Ensembl chr10:101,972,668...101,983,053 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases response to substance 		ISO enzalutamide promotes the reaction [Niclosamide results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Niclosamide inhibits the reaction [STAT3 protein results in decreased susceptibility to enzalutamide] CTD PMID:25970160 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Susd5 sushi domain containing 5 affects expression ISO enzalutamide affects the expression of SUSD5 mRNA CTD PMID:30940724 NCBI chr 8:113,996,771...114,036,133
Ensembl chr 8:113,997,362...114,035,861 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit multiple interactions
decreases expression 		ISO [enzalutamide co-treated with GSK-2816126] inhibits the reaction [AR protein binds to [EZH2 protein binds to SUZ12 protein binds to EED protein]]; enzalutamide promotes the reaction [GSK-2816126 results in decreased expression of SUZ12 protein]; GSK-2816126 promotes the reaction [enzalutamide results in decreased expression of SUZ12 protein] CTD PMID:32805266 NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738 		JBrowse link
G Tenm1 teneurin transmembrane protein 1 decreases expression ISO enzalutamide results in decreased expression of TENM1 mRNA CTD PMID:29581250 NCBI chr  X:121,400,466...122,289,877
Ensembl chr  X:121,403,649...122,290,207 		JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 decreases expression
multiple interactions 		ISO enzalutamide results in decreased expression of TMCC3 mRNA
KDM1A protein promotes the reaction [enzalutamide results in decreased expression of TMCC3 mRNA] 		CTD PMID:29581250 NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926 		JBrowse link
G Tpd52 tumor protein D52 decreases expression ISO enzalutamide results in decreased expression of TPD52 mRNA CTD PMID:29581250 NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622 		JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 decreases expression ISO enzalutamide results in decreased expression of TRPM8 mRNA CTD PMID:29581250 NCBI chr 9:88,897,039...88,990,167
Ensembl chr 9:88,903,880...88,988,552 		JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression ISO enzalutamide affects the expression of UBA52 mRNA CTD PMID:30940724 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807 		JBrowse link
G Ubb ubiquitin B affects expression ISO enzalutamide affects the expression of UBB mRNA CTD PMID:30940724 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
G Ubc ubiquitin C affects expression ISO enzalutamide affects the expression of UBC mRNA CTD PMID:30940724 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions ISO [enzalutamide co-treated with NVP-BHG712] results in decreased expression of UBE2C mRNA CTD PMID:32184358 NCBI chr 3:173,925,975...173,928,375
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Wdr12 WD repeat domain 12 affects expression ISO enzalutamide affects the expression of WDR12 mRNA CTD PMID:30940724 NCBI chr 9:61,475,498...61,502,762
Ensembl chr 9:61,475,517...61,502,469 		JBrowse link
G Wwtr1 WW domain containing transcription regulator 1 decreases expression ISO enzalutamide results in decreased expression of WWTR1 mRNA CTD PMID:29581250 NCBI chr 2:141,651,159...141,766,919
Ensembl chr 2:141,648,108...141,766,968 		JBrowse link
ethotoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO ethotoin binds to and results in increased activity of NR1I2 protein CTD PMID:15039302 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
Ethylenethiourea term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases expression
decreases activity 		EXP
ISO 		Ethylenethiourea results in decreased expression of ACHE protein
Ethylenethiourea results in decreased activity of ACHE protein 		CTD PMID:3868355 PMID:21251949 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Actl7a actin-like 7a decreases expression EXP Ethylenethiourea results in decreased expression of ACTL7A mRNA CTD PMID:27905518 NCBI chr 5:71,447,447...71,450,440
Ensembl chr 5:71,447,071...71,450,908 		JBrowse link
G Amh anti-Mullerian hormone decreases expression ISO Ethylenethiourea results in decreased expression of AMH protein CTD PMID:34571837 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO Ethylenethiourea results in decreased expression of ATP1A2 mRNA CTD PMID:33396126 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		ISO Ethylenethiourea results in decreased expression of BCL2 mRNA
[Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of BCL2 mRNA 		CTD PMID:27905518 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Pesticides results in increased abundance of Ethylenethiourea metabolite] which results in increased methylation of BDNF gene CTD PMID:35292247 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bex1 brain expressed X-linked 1 multiple interactions
decreases expression 		EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of BEX2 mRNA
Ethylenethiourea results in decreased expression of BEX2 mRNA 		CTD PMID:27905518 NCBI chr  X:99,219,014...99,220,518
Ensembl chr  X:99,219,014...99,220,958 		JBrowse link
G Bmp4 bone morphogenetic protein 4 decreases expression EXP Ethylenethiourea results in decreased expression of BMP4 mRNA CTD PMID:17161201 PMID:18082712 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
decreases expression
increases expression 		ISO Ethylenethiourea inhibits the reaction [Triiodothyronine results in increased expression of CYP19A1 mRNA]
Ethylenethiourea results in decreased expression of CYP19A1 mRNA; Ethylenethiourea results in decreased expression of CYP19A1 protein
Ethylenethiourea results in increased expression of CYP19A1 mRNA 		CTD PMID:34571837 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO CYP2D6 gene SNP affects the reaction [Ethylenethiourea affects the abundance of Hydrocortisone] CTD PMID:33771511 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression
multiple interactions 		EXP Ethylenethiourea results in decreased expression of DDIT4 mRNA
[Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of DDIT4 mRNA 		CTD PMID:27905518 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression ISO Ethylenethiourea results in decreased expression of DIO1 mRNA CTD PMID:34571837 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases expression
multiple interactions
affects expression 		ISO Ethylenethiourea results in decreased expression of DIO2 mRNA
[Ethylenethiourea co-treated with Triiodothyronine] results in decreased expression of DIO2 mRNA
Ethylenethiourea affects the expression of DIO2 mRNA 		CTD PMID:34571837 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dio3 iodothyronine deiodinase 3 increases expression
affects expression
decreases expression
multiple interactions 		ISO Ethylenethiourea results in increased expression of DIO3 mRNA
Ethylenethiourea affects the expression of DIO3 protein
Ethylenethiourea results in decreased expression of DIO3 mRNA
Ethylenethiourea inhibits the reaction [Triiodothyronine results in increased expression of DIO3 mRNA] 		CTD PMID:34571837 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660 		JBrowse link
G Egr1 early growth response 1 decreases expression
multiple interactions 		ISO
EXP 		Ethylenethiourea results in decreased expression of EGR1 mRNA
[Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of EGR1 mRNA 		CTD PMID:27905518 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 decreases expression ISO Ethylenethiourea results in decreased expression of ERGIC1 mRNA CTD PMID:27905518 NCBI chr10:16,531,192...16,626,974
Ensembl chr10:16,531,194...16,626,957 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Ethylenethiourea inhibits the reaction [Triiodothyronine results in increased expression of ESR1 mRNA] CTD PMID:34571837 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases oxidation
increases oxidation 		ISO FMO2 gene polymorphism results in decreased oxidation of Ethylenethiourea
FMO2 protein results in increased oxidation of Ethylenethiourea 		CTD PMID:15864117 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fscn2 fascin actin-bundling protein 2, retinal multiple interactions
decreases expression 		EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of FSCN2 mRNA
Ethylenethiourea results in decreased expression of FSCN2 mRNA 		CTD PMID:27905518 NCBI chr10:105,634,783...105,641,322
Ensembl chr10:105,634,783...105,641,322 		JBrowse link
G Fus Fus RNA binding protein decreases expression
multiple interactions 		EXP Ethylenethiourea results in decreased expression of FUS mRNA
[Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of FUS mRNA 		CTD PMID:27905518 NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414 		JBrowse link
G Fzd5 frizzled class receptor 5 decreases expression
multiple interactions 		ISO
EXP 		Ethylenethiourea results in decreased expression of FZD5 mRNA
[Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of FZD5 mRNA 		CTD PMID:27905518 NCBI chr 9:73,606,860...73,614,039
Ensembl chr 9:66,113,112...66,121,457 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression 		ISO [Triiodothyronine co-treated with Ethylenethiourea] results in increased expression of GJA1 mRNA
Ethylenethiourea results in increased expression of GJA1 mRNA 		CTD PMID:34571837 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gnao1 G protein subunit alpha o1 multiple interactions EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of GNAO1 mRNA CTD PMID:27905518 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gtf3c6 general transcription factor 3C subunit 6 multiple interactions EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of GTF3C6 mRNA CTD PMID:27905518 NCBI chr20:43,656,400...43,668,382
Ensembl chr20:43,655,875...43,667,873 		JBrowse link
G H2ax H2A.X variant histone increases phosphorylation EXP Ethylenethiourea results in increased phosphorylation of H2AX protein CTD PMID:37527026 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G H2bu1 H2B.U histone 1 decreases expression EXP Ethylenethiourea results in decreased expression of H2BU1 mRNA CTD PMID:27905518 NCBI chr10:43,732,737...43,733,484
Ensembl chr10:43,732,864...43,736,277 		JBrowse link
G Hexim2 HEXIM P-TEFb complex subunit 2 decreases expression EXP Ethylenethiourea results in decreased expression of HEXIM2 mRNA CTD PMID:27905518 NCBI chr10:88,077,870...88,084,776
Ensembl chr10:88,079,014...88,084,775 		JBrowse link
G Hmga1 high mobility group AT-hook 1 decreases expression
multiple interactions 		ISO
EXP 		Ethylenethiourea results in decreased expression of HMGA1 mRNA
[Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of HMGA1 mRNA 		CTD PMID:27905518 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752 		JBrowse link
G Hoxa13 homeo box A13 decreases expression EXP Ethylenethiourea results in decreased expression of HOXA13 mRNA CTD PMID:17161201 PMID:18082712 NCBI chr 4:81,358,956...81,361,091
Ensembl chr 4:81,358,956...81,361,091 		JBrowse link
G Hoxd13 homeo box D13 decreases expression EXP Ethylenethiourea results in decreased expression of HOXD13 mRNA CTD PMID:17161201 PMID:18082712 NCBI chr 3:59,570,647...59,573,963
Ensembl chr 3:59,570,646...59,573,963 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression EXP Ethylenethiourea results in decreased expression of IFIT3 mRNA CTD PMID:27905518 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [aminomethylphosphonic acid (AMPA) co-treated with 2,4-Dichlorophenoxyacetic Acid metabolite co-treated with Ethylenethiourea co-treated with desethylatrazine] results in decreased expression of IL1B protein CTD PMID:37236337 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Inha inhibin subunit alpha decreases expression
multiple interactions 		ISO Ethylenethiourea results in decreased expression of INHA mRNA
[Triiodothyronine co-treated with Ethylenethiourea] results in decreased expression of INHA mRNA 		CTD PMID:34571837 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J multiple interactions EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of INPP5J mRNA CTD PMID:27905518 NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 increases expression EXP Ethylenethiourea results in increased expression of JAG1 mRNA alternative form CTD PMID:35930101 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP Ethylenethiourea results in increased expression of MKI67 protein CTD PMID:37527026 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 multiple interactions EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of PAK2 mRNA CTD PMID:27905518 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Pom121l2 POM121 transmembrane nucleoporin-like 2 decreases expression EXP Ethylenethiourea results in decreased expression of POM121L2 mRNA CTD PMID:27905518 NCBI chr17:42,546,144...42,553,447
Ensembl chr17:42,546,326...42,553,423 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions
decreases expression 		ISO Ethylenethiourea inhibits the reaction [Triiodothyronine results in increased expression of POU5F1 mRNA]
Ethylenethiourea results in decreased expression of POU5F1 mRNA 		CTD PMID:34571837 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Reep6 receptor accessory protein 6 multiple interactions EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of REEP6 mRNA CTD PMID:27905518 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597 		JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of RUNX2 mRNA CTD PMID:27905518 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Shh sonic hedgehog signaling molecule decreases expression EXP Ethylenethiourea results in decreased expression of SHH mRNA CTD PMID:16369776 PMID:17161201 PMID:18082712 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sox9 SRY-box transcription factor 9 increases expression
multiple interactions
decreases expression 		EXP
ISO 		Ethylenethiourea results in increased expression of SOX9 protein
[Triiodothyronine co-treated with Ethylenethiourea] results in decreased expression of SOX9 mRNA
Ethylenethiourea results in decreased expression of SOX9 mRNA 		CTD PMID:34571837 PMID:35930101 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions
decreases expression 		ISO [Triiodothyronine co-treated with Ethylenethiourea] results in decreased expression of STAR mRNA
Ethylenethiourea results in decreased expression of STAR mRNA 		CTD PMID:34571837 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stra8 stimulated by retinoic acid 8 decreases expression
multiple interactions 		ISO Ethylenethiourea results in decreased expression of STRA8 mRNA
[Ethylenethiourea co-treated with Triiodothyronine] results in decreased expression of STRA8 mRNA 		CTD PMID:34571837 NCBI chr 4:63,601,443...63,624,777
Ensembl chr 4:63,601,604...63,624,771 		JBrowse link
G Sycp1 synaptonemal complex protein 1 decreases expression
multiple interactions 		ISO Ethylenethiourea results in decreased expression of SYCP1 mRNA
[Ethylenethiourea co-treated with Triiodothyronine] results in decreased expression of SYCP1 mRNA 		CTD PMID:34571837 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737 		JBrowse link
G Tent5d terminal nucleotidyltransferase 5D decreases expression EXP Ethylenethiourea results in decreased expression of TENT5D mRNA CTD PMID:27905518 NCBI chr  X:72,901,287...72,974,562
Ensembl chr  X:72,901,241...72,970,573 		JBrowse link
G Tg thyroglobulin decreases expression
multiple interactions 		ISO Ethylenethiourea results in decreased expression of TG mRNA
[Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of TG mRNA 		CTD PMID:27905518 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions
decreases expression 		ISO [Triiodothyronine co-treated with Ethylenethiourea] results in decreased expression of THRA mRNA
Ethylenethiourea results in decreased expression of THRA mRNA 		CTD PMID:34571837 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta decreases expression
multiple interactions 		ISO Ethylenethiourea results in decreased expression of THRB mRNA
Ethylenethiourea inhibits the reaction [Triiodothyronine results in increased expression of THRB mRNA] 		CTD PMID:34571837 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Thrsp thyroid hormone responsive decreases expression
multiple interactions 		ISO Ethylenethiourea results in decreased expression of THRSP mRNA
[Ethylenethiourea co-treated with Triiodothyronine] results in increased expression of THRSP mRNA 		CTD PMID:34571837 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075 		JBrowse link
G Tpo thyroid peroxidase decreases activity
affects activity 		ISO Ethylenethiourea results in decreased activity of TPO protein
Ethylenethiourea affects the activity of TPO protein 		CTD PMID:7626075 PMID:9248629 PMID:31629072 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Wnt4 Wnt family member 4 multiple interactions
decreases expression 		ISO [Triiodothyronine co-treated with Ethylenethiourea] results in decreased expression of WNT4 mRNA
Ethylenethiourea results in decreased expression of WNT4 mRNA 		CTD PMID:34571837 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
G Zfp362 zinc finger protein 362 multiple interactions EXP [Chlorpyrifos co-treated with Ethylenethiourea] results in decreased expression of ZFP362 mRNA CTD PMID:27905518 NCBI chr 5:141,119,073...141,153,304
Ensembl chr 5:141,119,898...141,156,716 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 decreases expression EXP
ISO 		Ethylenethiourea results in decreased expression of ZFP36L2 mRNA CTD PMID:27905518 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064 		JBrowse link
G Zfp524 zinc finger protein 524 decreases expression EXP
ISO 		Ethylenethiourea results in decreased expression of ZFP524 mRNA CTD PMID:27905518 NCBI chr 1:68,824,803...68,828,363
Ensembl chr 1:68,824,803...68,828,594 		JBrowse link
G Zfp703 zinc finger protein 703 decreases expression EXP Ethylenethiourea results in decreased expression of ZFP703 mRNA CTD PMID:27905518 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677 		JBrowse link
Hydroxymephenytoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 increases chemical synthesis
multiple interactions 		ISO CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin
[CYP2C19 protein results in increased hydroxylation of Mephenytoin] which results in increased chemical synthesis of 4-hydroxymephenytoin; [CYP2C19 protein results in increased metabolism of Mephenytoin] which results in increased chemical synthesis of 4-hydroxymephenytoin; Fluoxetine inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased chemical synthesis of 4-hydroxymephenytoin] 		CTD PMID:12401345 PMID:15155557 PMID:21915887 PMID:23850985 PMID:25084468 More... NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
imidacloprid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700012B07Rikl RIKEN cDNA 1700012B07 gene like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of 1700012B07RIKL gene CTD PMID:33854195 NCBI chr10:94,771,471...94,804,839
Ensembl chr10:94,771,554...94,804,839 		JBrowse link
G Acacb acetyl-CoA carboxylase beta multiple interactions ISO [imidacloprid co-treated with Dietary Fats] results in increased expression of ACACB mRNA CTD PMID:33487623 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Ache acetylcholinesterase increases activity
decreases activity
increases expression 		EXP imidacloprid results in increased activity of ACHE protein
imidacloprid results in decreased activity of ACHE protein
imidacloprid results in increased expression of ACHE protein 		CTD PMID:18080902 PMID:26024013 PMID:37648049 PMID:39002876 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ACOT2 gene CTD PMID:33854195 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ACOT4 mRNA CTD PMID:33854195 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression
decreases expression 		ISO imidacloprid results in increased expression of ACOX1 mRNA
imidacloprid results in decreased expression of ACOX1 mRNA 		CTD PMID:33487623 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acy1 aminoacylase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ACY1 mRNA CTD PMID:33854195 NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682 		JBrowse link
G Adam15 ADAM metallopeptidase domain 15 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ADAM15 gene CTD PMID:33854195 NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113 		JBrowse link
G Adamtsl3 ADAMTS-like 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of ADAMTSL3 gene CTD PMID:33854195 NCBI chr 1:136,288,793...136,596,986
Ensembl chr 1:136,288,793...136,596,986 		JBrowse link
G Adcy6 adenylate cyclase 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ADCY6 mRNA CTD PMID:33854195 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754 		JBrowse link
G Adrm1 ADRM1 26S proteasome ubiquitin receptor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ADRM1 mRNA CTD PMID:33854195 NCBI chr 3:167,265,435...167,270,197
Ensembl chr 3:167,265,296...167,270,195 		JBrowse link
G Afp alpha-fetoprotein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of AFP mRNA CTD PMID:33854195 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Agt angiotensinogen multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of AGT mRNA CTD PMID:33854195 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ahr aryl hydrocarbon receptor affects expression ISO imidacloprid affects the expression of AHR mRNA CTD PMID:35457321 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression EXP imidacloprid results in increased expression of AIF1 mRNA CTD PMID:39002876 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Aig1 androgen-induced 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of AIG1 gene CTD PMID:33854195 NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084 		JBrowse link
G Akap8 A-kinase anchoring protein 8 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of AKAP8 mRNA CTD PMID:33854195 NCBI chr 7:11,316,224...11,332,523
Ensembl chr 7:11,316,228...11,332,399 		JBrowse link
G Akap8l A-kinase anchoring protein 8 like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of AKAP8L mRNA CTD PMID:33854195 NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275 		JBrowse link
G Alb albumin multiple interactions
decreases expression 		EXP [imidacloprid co-treated with sodium arsenate] results in decreased expression of ALB protein
imidacloprid results in decreased expression of ALB protein 		CTD PMID:30033815 PMID:34993831 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ALDH9A1 mRNA CTD PMID:33854195 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568 		JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ALG2 mRNA CTD PMID:33854195 NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297 		JBrowse link
G Ampd1 adenosine monophosphate deaminase 1 decreases expression EXP imidacloprid results in decreased expression of AMPD1 mRNA CTD PMID:27782041 NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938 		JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ANGPTL4 mRNA CTD PMID:33854195 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Anks3 ankyrin repeat and sterile alpha motif domain containing 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ANKS3 mRNA CTD PMID:33854195 NCBI chr10:10,614,953...10,635,815
Ensembl chr10:10,615,047...10,635,806 		JBrowse link
G Anxa11 annexin A11 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ANXA11 mRNA CTD PMID:33854195 NCBI chr16:1,412,373...1,457,814
Ensembl chr16:1,410,756...1,457,797 		JBrowse link
G Apc APC regulator of WNT signaling pathway affects methylation
multiple interactions 		ISO imidacloprid affects the methylation of APC promoter
LIF protein affects the reaction [imidacloprid affects the methylation of APC promoter] 		CTD PMID:33865946 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Aplf aprataxin and PNKP like factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of APLF mRNA CTD PMID:33854195 NCBI chr 4:120,070,471...120,122,656
Ensembl chr 4:120,070,471...120,122,633 		JBrowse link
G Apof apolipoprotein F multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of APOF mRNA CTD PMID:33854195 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946 		JBrowse link
G Ar androgen receptor decreases expression
affects expression 		ISO imidacloprid results in decreased expression of AR mRNA; imidacloprid results in decreased expression of AR protein
imidacloprid affects the expression of AR mRNA 		CTD PMID:31780179 PMID:35457321 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arf2 ADP-ribosylation factor 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ARF2 mRNA CTD PMID:33854195 NCBI chr10:88,867,836...88,889,654
Ensembl chr10:88,867,836...88,889,659 		JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of ARPC1A gene CTD PMID:33854195 NCBI chr12:9,502,496...9,525,304
Ensembl chr12:9,502,501...9,525,330 		JBrowse link
G Asb7 ankyrin repeat and SOCS box-containing 7 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ASB7 mRNA CTD PMID:33854195 NCBI chr 1:120,222,835...120,267,411
Ensembl chr 1:120,222,745...120,267,282 		JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ASS1 mRNA CTD PMID:33854195 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Atosa atos homolog A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ATOSA mRNA CTD PMID:33854195 NCBI chr 8:75,694,828...75,772,565
Ensembl chr 8:75,695,022...75,772,549 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ATP5MC1 mRNA CTD PMID:33854195 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ATP6V0D1 mRNA CTD PMID:33854195 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450 		JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BAG3 mRNA CTD PMID:33854195 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Banp Btg3 associated nuclear protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BANP mRNA CTD PMID:33854195 NCBI chr19:50,007,710...50,082,742
Ensembl chr19:50,007,881...50,082,738 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions 		EXP imidacloprid results in increased expression of BAX mRNA; imidacloprid results in increased expression of BAX protein
Thymol inhibits the reaction [imidacloprid results in increased expression of BAX mRNA] 		CTD PMID:27914857 PMID:34171690 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase increases activity EXP imidacloprid results in increased activity of BCHE protein CTD PMID:18080902 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		EXP imidacloprid results in decreased expression of BCL2 mRNA
Thymol inhibits the reaction [imidacloprid results in decreased expression of BCL2 mRNA] 		CTD PMID:34171690 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP imidacloprid results in decreased expression of BCL2L1 mRNA CTD PMID:39002876 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl9 BCL9, transcription coactivator multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of BCL9 mRNA CTD PMID:33854195 NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of BHMT mRNA CTD PMID:33854195 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G C1qc complement C1q C chain multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of C1QC mRNA CTD PMID:33854195 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017 		JBrowse link
G C8h11orf54 similar to human chromosome 11 open reading frame 54 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of C8H11ORF54 mRNA CTD PMID:33854195 NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression EXP imidacloprid results in increased expression of CACNA1H mRNA CTD PMID:27782041 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 decreases expression EXP imidacloprid results in decreased expression of CACNG1 mRNA CTD PMID:27782041 NCBI chr10:92,652,924...92,665,612
Ensembl chr10:92,652,614...92,665,783 		JBrowse link
G Camk2g calcium/calmodulin-dependent protein kinase II gamma multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CAMK2G mRNA CTD PMID:33854195 NCBI chr15:3,553,238...3,612,310
Ensembl chr15:3,504,085...3,563,050 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression
multiple interactions 		ISO imidacloprid results in decreased expression of CAMKK2 protein
Dietary Fats promotes the reaction [imidacloprid results in decreased expression of CAMKK2 protein] 		CTD PMID:27960282 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CAP1 mRNA CTD PMID:33854195 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769 		JBrowse link
G Caps2 calcyphosine 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CAPS2 mRNA CTD PMID:33854195 NCBI chr 7:47,580,636...47,641,598
Ensembl chr 7:47,581,137...47,639,229 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions 		EXP imidacloprid results in increased expression of CASP3 mRNA; imidacloprid results in increased expression of CASP3 protein
Thymol inhibits the reaction [imidacloprid results in increased expression of CASP3 mRNA]; Thymol inhibits the reaction [imidacloprid results in increased expression of CASP3 protein] 		CTD PMID:34171690 PMID:34993831 PMID:37648049 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase decreases activity
decreases expression
multiple interactions 		EXP imidacloprid results in decreased activity of CAT protein
imidacloprid results in decreased expression of CAT protein
imidacloprid promotes the reaction [sodium arsenate results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [imidacloprid results in decreased expression of CAT protein]; sodium arsenate promotes the reaction [imidacloprid results in decreased activity of CAT protein]; Thymol inhibits the reaction [imidacloprid results in decreased activity of CAT protein] 		CTD PMID:20686345 PMID:30033815 PMID:30456172 PMID:34171690 PMID:35398170 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbs cystathionine beta synthase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CBS mRNA CTD PMID:33854195 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccdc125 coiled-coil domain containing 125 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCDC125 mRNA CTD PMID:33854195 NCBI chr 2:31,809,120...31,835,538
Ensembl chr 2:31,809,228...31,850,152 		JBrowse link
G Ccdc81 coiled-coil domain containing 81 increases expression EXP imidacloprid results in increased expression of CCDC81 mRNA CTD PMID:27782041 NCBI chr 1:143,739,472...143,791,026
Ensembl chr 1:143,739,474...143,790,926 		JBrowse link
G Ccnl1 cyclin L1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCNL1 mRNA CTD PMID:33854195 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368 		JBrowse link
G Cd36 CD36 molecule increases expression
multiple interactions 		ISO imidacloprid results in increased expression of CD36 mRNA
[imidacloprid co-treated with Dietary Fats] results in decreased expression of CD36 mRNA; [imidacloprid co-treated with Dietary Fats] results in increased expression of CD36 mRNA 		CTD PMID:27960282 PMID:33487623 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
affects methylation 		ISO LIF protein affects the reaction [imidacloprid affects the methylation of CDH1 promoter] CTD PMID:33865946 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CDKN1A mRNA CTD PMID:33854195 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A affects methylation
multiple interactions 		ISO imidacloprid affects the methylation of CDKN2A promoter
LIF protein affects the reaction [imidacloprid affects the methylation of CDKN2A promoter] 		CTD PMID:33865946 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CEBPD mRNA CTD PMID:33854195 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression EXP imidacloprid results in increased expression of CELF6 mRNA CTD PMID:27782041 NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041 		JBrowse link
G Cep85 centrosomal protein 85 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CEP85 mRNA CTD PMID:33854195 NCBI chr 5:146,356,571...146,404,155
Ensembl chr 5:146,356,576...146,404,060 		JBrowse link
G Cerk ceramide kinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CERK mRNA CTD PMID:33854195 NCBI chr 7:117,225,855...117,269,436
Ensembl chr 7:117,225,855...117,268,759 		JBrowse link
G Cfb complement factor B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CFB mRNA CTD PMID:33854195 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cfl1 cofilin 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CFL1 mRNA CTD PMID:33854195 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Chat choline O-acetyltransferase increases expression EXP imidacloprid results in increased expression of CHAT mRNA CTD PMID:39002876 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CHCHD10 mRNA CTD PMID:33854195 NCBI chr20:12,725,839...12,727,638
Ensembl chr20:12,725,842...12,732,763 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CHEK2 mRNA CTD PMID:33854195 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression EXP imidacloprid results in increased expression of CHRM1 mRNA CTD PMID:26568164 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 increases expression EXP imidacloprid results in increased expression of CHRM2 protein CTD PMID:18080902 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit multiple interactions EXP imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]; LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]; LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions ISO imidacloprid results in increased activity of [CHRNA3 protein binds to CHRNB4 protein] CTD PMID:34628512 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP
ISO 		imidacloprid analog inhibits the reaction [Nicotine analog binds to [CHRNA4 protein co-treated with CHRNB2 protein]]; imidacloprid binds to [CHRNA4 protein co-treated with CHRNB2 protein]
imidacloprid inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; imidacloprid results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]; imidacloprid results in increased activity of [CHRNA4 protein binds to CHRNB4 protein] 		CTD PMID:10377228 PMID:10728888 PMID:21538459 PMID:34628512 NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases activity ISO imidacloprid metabolite results in increased activity of CHRNA7 protein; imidacloprid results in increased activity of CHRNA7 protein; imidacloprid results in increased activity of CHRNA7 protein mutant form CTD PMID:34628512 PMID:39393466 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions
decreases expression 		EXP
ISO 		[NACHRA8 protein co-treated with CHRNB2 protein] affects the susceptibility to imidacloprid; imidacloprid analog inhibits the reaction [Nicotine analog binds to [CHRNA4 protein co-treated with CHRNB2 protein]]; imidacloprid binds to [CHRNA4 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA1 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA2 protein co-treated with CHRNB2 protein]; imidacloprid binds to [NACHRALPHA3 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]; imidacloprid results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRALPHA1 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRALPHA1 protein co-treated with NACHRALPHA2 protein co-treated with CHRNB2 protein]; imidacloprid results in increased activity of [NACHRALPHA2 protein co-treated with CHRNB2 protein]; LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]; LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]]
imidacloprid results in decreased expression of CHRNB2 mRNA
imidacloprid inhibits the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]; imidacloprid results in increased activity of [CHRNA4 protein binds to CHRNB2 protein] 		CTD PMID:10377228 PMID:10728888 PMID:16291090 PMID:16981889 PMID:18824080 More... NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO imidacloprid results in increased activity of [CHRNA3 protein binds to CHRNB4 protein]; imidacloprid results in increased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:34628512 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions ISO [imidacloprid co-treated with Dietary Fats] results in increased expression of CIDEA mRNA CTD PMID:33487623 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cirbp cold inducible RNA binding protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CIRBP mRNA CTD PMID:33854195 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CLCF1 mRNA CTD PMID:33854195 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Cldn1 claudin 1 decreases expression EXP imidacloprid results in decreased expression of CLDN1 mRNA CTD PMID:27792329 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Clec2g C-type lectin domain family 2, member G multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CLEC2G mRNA CTD PMID:33854195 NCBI chr 4:162,617,827...162,627,699
Ensembl chr 4:162,617,790...162,627,699 		JBrowse link
G Clu clusterin multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CLU mRNA CTD PMID:33854195 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cndp2 carnosine dipeptidase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CNDP2 mRNA CTD PMID:33854195 NCBI chr18:78,039,924...78,057,030
Ensembl chr18:78,039,932...78,056,922 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CPT2 mRNA CTD PMID:33854195 NCBI chr 5:127,893,450...127,911,347
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Crb3 crumbs cell polarity complex component 3 increases expression EXP imidacloprid results in increased expression of CRB3 mRNA CTD PMID:27782041 NCBI chr 9:1,898,531...1,903,860
Ensembl chr 9:1,896,623...1,903,859 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CRY1 mRNA CTD PMID:33854195 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Cspp1 centrosome and spindle pole associated protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CSPP1 mRNA CTD PMID:33854195 NCBI chr 5:9,077,161...9,192,402
Ensembl chr 5:9,077,161...9,193,377 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CSRNP1 mRNA CTD PMID:33854195 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Cth cystathionine gamma-lyase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of CTH gene CTD PMID:33854195 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnal1 catenin alpha-like 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CTNNAL1 mRNA CTD PMID:33854195 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431 		JBrowse link
G Ctnnd1 catenin delta 1 increases expression EXP imidacloprid results in increased expression of CTNND1 mRNA CTD PMID:27792329 NCBI chr 3:69,683,328...69,734,550
Ensembl chr 3:69,683,313...69,734,516 		JBrowse link
G Cux2 cut-like homeobox 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CUX2 mRNA CTD PMID:33854195 NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions 		ISO
EXP 		imidacloprid results in decreased expression of CYP11A1 mRNA
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP11A1 mRNA] 		CTD PMID:31780179 PMID:34171690 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
multiple interactions 		EXP
ISO 		imidacloprid results in decreased expression of CYP17A1 mRNA
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP17A1 mRNA] 		CTD PMID:27782041 PMID:31780179 PMID:34171690 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
decreases expression
multiple interactions
affects expression 		ISO
EXP 		imidacloprid results in increased activity of CYP19A1 protein
imidacloprid results in decreased expression of CYP19A1 mRNA
Thymol inhibits the reaction [imidacloprid results in decreased expression of CYP19A1 mRNA]
imidacloprid affects the expression of CYP19A1 mRNA
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione affects the reaction [imidacloprid affects the expression of CYP19A1 mRNA] 		CTD PMID:28750898 PMID:29701941 PMID:34171690 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO imidacloprid results in increased expression of CYP2B10 mRNA CTD PMID:36320626 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP2C22 mRNA CTD PMID:33854195 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP imidacloprid results in increased expression of CYP2E1 mRNA CTD PMID:37632782 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [NADP co-treated with CYP3A4 protein] results in increased activity of imidacloprid analog CTD PMID:16153789 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP4A1 mRNA CTD PMID:33854195 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of CYP4F1 mRNA CTD PMID:33854195 NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression EXP imidacloprid results in increased expression of CYP4F18 mRNA CTD PMID:37632782 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
G Cytip cytohesin 1 interacting protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CYTIP mRNA CTD PMID:33854195 NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DBP mRNA CTD PMID:33854195 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745 		JBrowse link
G Dclre1c DNA cross-link repair 1C multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DCLRE1C mRNA CTD PMID:33854195 NCBI chr17:74,775,828...74,810,089
Ensembl chr17:74,776,935...74,809,186 		JBrowse link
G Ddx20 DEAD-box helicase 20 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DDX20 mRNA CTD PMID:33854195 NCBI chr 2:193,158,761...193,168,484
Ensembl chr 2:193,158,823...193,166,774 		JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DDX5 mRNA CTD PMID:33854195 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Dffb DNA fragmentation factor subunit beta multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DFFB mRNA CTD PMID:33854195 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DLG2 gene CTD PMID:33854195 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DLL1 mRNA CTD PMID:33854195 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DMRT3 gene CTD PMID:33854195 NCBI chr 1:223,244,340...223,264,254
Ensembl chr 1:223,248,747...223,262,530 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DNAJB1 mRNA CTD PMID:33854195 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DNAJB9 mRNA CTD PMID:33854195 NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of DPP4 mRNA CTD PMID:33854195 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression EXP imidacloprid results in decreased expression of DPYSL3 mRNA CTD PMID:39002876 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DUSP1 mRNA CTD PMID:33854195 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DUSP5 gene CTD PMID:33854195 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of DUSP6 mRNA CTD PMID:33854195 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dzip1l DAZ interacting zinc finger protein 1-like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of DZIP1L gene CTD PMID:33854195 NCBI chr 8:100,188,414...100,229,077
Ensembl chr 8:100,194,999...100,228,988 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 multiple interactions ISO [imidacloprid co-treated with Dietary Fats] results in increased expression of ELOVL6 mRNA CTD PMID:33487623 NCBI chr 2:220,738,095...220,845,528
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of EMILIN1 mRNA CTD PMID:33854195 NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ENPP3 mRNA CTD PMID:33854195 NCBI chr 1:20,563,700...20,635,044
Ensembl chr 1:20,563,697...20,635,041 		JBrowse link
G Epb41l3 erythrocyte membrane protein band 4.1-like 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of EPB41L3 gene CTD PMID:33854195 NCBI chr 9:109,056,178...109,260,607
Ensembl chr 9:109,016,113...109,260,607 		JBrowse link
G Epm2aip1 EPM2A interacting protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of EPM2AIP1 mRNA CTD PMID:33854195 NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871 		JBrowse link
G Erf Ets2 repressor factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ERF mRNA CTD PMID:33854195 NCBI chr 1:80,829,935...80,838,388
Ensembl chr 1:80,829,935...80,838,388 		JBrowse link
G Esd esterase D multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ESD mRNA CTD PMID:33854195 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144 		JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO imidacloprid results in increased expression of ESR1 mRNA CTD PMID:35457321 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 affects expression ISO imidacloprid affects the expression of ESR2 mRNA CTD PMID:35457321 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 increases expression EXP imidacloprid results in increased expression of F2RL2 mRNA CTD PMID:27782041 NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098 		JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [imidacloprid co-treated with Dietary Fats] results in decreased expression of FABP4 mRNA CTD PMID:33487623 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fam135a family with sequence similarity 135, member A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM135A mRNA CTD PMID:33854195 NCBI chr 9:26,420,116...26,500,803
Ensembl chr 9:26,420,528...26,500,717 		JBrowse link
G Fam177a1 family with sequence similarity 177, member A1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of FAM177A1 gene CTD PMID:33854195 NCBI chr 6:72,632,628...72,647,553
Ensembl chr 6:72,632,623...72,647,553 		JBrowse link
G Fam204a family with sequence similarity 204, member A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FAM204A mRNA CTD PMID:33854195 NCBI chr 1:259,328,551...259,366,726
Ensembl chr 1:259,337,709...259,367,077 		JBrowse link
G Fam53a family with sequence similarity 53, member A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of FAM53A gene CTD PMID:33854195 NCBI chr14:77,088,178...77,124,395
Ensembl chr14:77,090,723...77,124,395 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [imidacloprid co-treated with Dietary Fats] results in increased expression of FAS mRNA CTD PMID:33487623 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Ficd FIC domain protein adenylyltransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of FICD mRNA CTD PMID:33854195 NCBI chr12:42,889,195...42,894,090
Ensembl chr12:42,889,194...42,894,070 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of FKBP4 mRNA CTD PMID:33854195 NCBI chr 4:163,389,464...163,397,918
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of FKBP5 gene CTD PMID:33854195 NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fmn1 formin 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FMN1 mRNA CTD PMID:33854195 NCBI chr 3:100,101,103...100,485,652
Ensembl chr 3:100,134,549...100,479,220 		JBrowse link
G Frmd4b FERM domain containing 4B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FRMD4B mRNA CTD PMID:33854195 NCBI chr 4:129,895,401...130,222,070
Ensembl chr 4:129,895,708...130,084,197 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
increases expression 		EXP Thymol inhibits the reaction [imidacloprid results in increased expression of FSHB protein] CTD PMID:34171690 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fzd6 frizzled class receptor 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of FZD6 mRNA CTD PMID:33854195 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GADD45G mRNA CTD PMID:33854195 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 increases expression EXP imidacloprid results in increased expression of GALNT7 mRNA CTD PMID:27782041 NCBI chr16:32,578,643...32,703,189
Ensembl chr16:32,578,690...32,702,690 		JBrowse link
G Gatd3a glutamine amidotransferase class 1 domain containing 3A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GATD3A mRNA CTD PMID:33854195 NCBI chr20:10,514,459...10,522,556
Ensembl chr20:10,514,744...10,522,885 		JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GDF15 mRNA CTD PMID:33854195 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP imidacloprid results in increased expression of GFAP mRNA; imidacloprid results in increased expression of GFAP protein CTD PMID:18080902 PMID:39002876 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gin1 gypsy retrotransposon integrase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GIN1 mRNA CTD PMID:33854195 NCBI chr 9:98,293,596...98,315,155
Ensembl chr 9:98,293,597...98,315,848 		JBrowse link
G Git2 GIT ArfGAP 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GIT2 mRNA CTD PMID:33854195 NCBI chr12:41,829,717...41,872,621
Ensembl chr12:41,829,730...41,871,097 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP imidacloprid results in decreased expression of GJA1 mRNA CTD PMID:27792329 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Glb1 galactosidase, beta 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GLB1 mRNA CTD PMID:33854195 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Gnpda2 glucosamine-6-phosphate deaminase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GNPDA2 mRNA CTD PMID:33854195 NCBI chr14:38,520,663...38,538,713
Ensembl chr14:38,520,705...38,538,713 		JBrowse link
G Gprasp3 G protein-coupled receptor associated sorting protein family member 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GPRASP3 mRNA CTD PMID:33854195 NCBI chr  X:98,847,591...98,854,949
Ensembl chr  X:98,817,593...98,854,545 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity
multiple interactions
increases expression 		EXP
ISO 		imidacloprid results in increased activity of GPT protein
[imidacloprid co-treated with Dietary Fats] results in increased expression of GPT protein
imidacloprid results in increased expression of GPT protein
[imidacloprid co-treated with fipronil co-treated with Glyphosate] results in increased activity of and results in increased secretion of GPT protein
[imidacloprid co-treated with sodium arsenate] results in increased activity of GPT protein 		CTD PMID:30033815 PMID:33487623 PMID:34993831 PMID:35850439 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression EXP imidacloprid results in decreased expression of GPX1 mRNA CTD PMID:39002876 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP imidacloprid results in increased expression of GPX4 mRNA CTD PMID:39002876 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Gramd1a GRAM domain containing 1A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of GRAMD1A mRNA CTD PMID:33854195 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of GRIA1 gene CTD PMID:33854195 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GRINA mRNA CTD PMID:33854195 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Gsdma gasdermin A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of GSDMA gene CTD PMID:33854195 NCBI chr10:83,614,336...83,639,543
Ensembl chr10:83,627,051...83,639,543 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
decreases activity 		EXP imidacloprid promotes the reaction [sodium arsenate results in decreased activity of GSR protein]; sodium arsenate promotes the reaction [imidacloprid results in decreased activity of GSR protein] CTD PMID:30033815 PMID:30456172 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of GSTK1 mRNA CTD PMID:33854195 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292 		JBrowse link
G Hao1 hydroxyacid oxidase 1 decreases expression EXP imidacloprid results in decreased expression of HAO1 mRNA CTD PMID:27782041 NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721 		JBrowse link
G Hapstr2 HUWE1 associated protein modifying stress responses 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of HAPSTR2 gene CTD PMID:33854195 NCBI chr  X:138,922,089...138,924,124
Ensembl chr  X:138,922,100...138,922,918 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HARS1 mRNA CTD PMID:33854195 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740 		JBrowse link
G Hebp1 heme binding protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HEBP1 mRNA CTD PMID:33854195 NCBI chr 4:167,974,316...168,003,854
Ensembl chr 4:167,974,319...168,003,854 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of HES1 mRNA CTD PMID:33854195 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hjv hemojuvelin BMP co-receptor decreases expression EXP imidacloprid results in decreased expression of HJV mRNA CTD PMID:27782041 NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression ISO imidacloprid results in decreased expression of HMGCR mRNA CTD PMID:31780179 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression 		EXP imidacloprid results in increased expression of HMOX1 mRNA
imidacloprid affects the expression of HMOX1 mRNA 		CTD PMID:34993831 PMID:39002876 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hs3st3b1 heparan sulfate-glucosamine 3-sulfotransferase 3B1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HS3ST3B1 mRNA CTD PMID:33854195 NCBI chr10:48,561,473...48,593,970
Ensembl chr10:48,561,473...48,593,970 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD11B2 mRNA CTD PMID:33854195 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSD17B10 mRNA CTD PMID:33854195 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of HSD17B2 mRNA CTD PMID:33854195 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions
decreases expression 		EXP Thymol inhibits the reaction [imidacloprid results in decreased expression of HSD17B3 mRNA] CTD PMID:34171690 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 decreases expression EXP imidacloprid results in decreased expression of HSD3B2 mRNA CTD PMID:27914857 NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO imidacloprid results in decreased expression of HSP90B1 protein CTD PMID:16884889 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSPA1B mRNA CTD PMID:33854195 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO imidacloprid results in decreased expression of HSPA5 protein CTD PMID:16884889 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression ISO imidacloprid results in decreased expression of HSPB1 protein CTD PMID:16884889 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspb7 heat shock protein family B (small) member 7 decreases expression EXP imidacloprid results in decreased expression of HSPB7 mRNA CTD PMID:27782041 NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266 		JBrowse link
G Hspbp1 HSPA (Hsp70) binding protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of HSPBP1 mRNA CTD PMID:33854195 NCBI chr 1:69,165,394...69,189,062
Ensembl chr 1:69,165,572...69,244,593 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C increases expression EXP imidacloprid results in increased expression of HTR2C mRNA CTD PMID:27782041 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Ier3 immediate early response 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of IER3 mRNA CTD PMID:33854195 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ifna12l interferon alpha 12 like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of IFNA12L gene CTD PMID:33854195 NCBI chr 5:103,476,362...103,477,427
Ensembl chr 5:103,476,657...103,477,211
Ensembl chr 5:103,476,657...103,477,211
Ensembl chr 5:103,476,657...103,477,211 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of IGFBP1 mRNA CTD PMID:33854195 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igkv2-112l2 immunoglobulin kappa variable 2-112 like 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of IGKV2-112L2 gene CTD PMID:33854195 NCBI chr 4:102,208,069...102,208,647
Ensembl chr 4:102,208,044...102,208,785 		JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression 		EXP Plant Extracts inhibits the reaction [imidacloprid results in decreased expression of IL10 mRNA] CTD PMID:35398170 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions 		EXP
ISO 		imidacloprid results in increased expression of IL1B mRNA
[imidacloprid co-treated with Dietary Fats] results in decreased expression of IL1B mRNA
Plant Extracts inhibits the reaction [imidacloprid results in increased expression of IL1B mRNA] 		CTD PMID:33487623 PMID:35398170 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il4 interleukin 4 increases expression EXP imidacloprid results in increased expression of IL4 mRNA CTD PMID:39002876 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 multiple interactions
affects expression
increases expression 		EXP
ISO 		Plant Extracts inhibits the reaction [imidacloprid results in increased expression of IL6 mRNA]
imidacloprid affects the expression of IL6 mRNA
[imidacloprid co-treated with Dietary Fats] results in decreased expression of IL6 mRNA 		CTD PMID:33487623 PMID:35398170 PMID:39002876 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of INPP5F mRNA CTD PMID:33854195 NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276 		JBrowse link
G Ins1 insulin 1 decreases expression
increases secretion
multiple interactions 		EXP
ISO 		imidacloprid results in decreased expression of INS1 protein
imidacloprid results in increased secretion of INS1 protein
Dietary Fats promotes the reaction [imidacloprid results in increased secretion of INS1 protein]; imidacloprid promotes the reaction [Dietary Fats results in increased secretion of INS1 protein] 		CTD PMID:27960282 PMID:28850943 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Iqcb1 IQ motif containing B1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of IQCB1 mRNA CTD PMID:33854195 NCBI chr11:63,905,595...63,960,141
Ensembl chr11:63,905,590...63,960,093 		JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of IRF2BP2 mRNA CTD PMID:33854195 NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642 		JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of ITPRIP mRNA CTD PMID:33854195 NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408 		JBrowse link
G Itpripl1 ITPRIP like 1 decreases expression EXP imidacloprid results in decreased expression of ITPRIPL1 mRNA CTD PMID:27782041 NCBI chr 3:114,403,123...114,407,917
Ensembl chr 3:114,402,270...114,414,497 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of JUNB mRNA CTD PMID:33854195 NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Katnip katanin interacting protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of KATNIP gene CTD PMID:33854195 NCBI chr 1:180,270,194...180,436,766
Ensembl chr 1:180,269,929...180,436,766 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression EXP imidacloprid results in decreased expression of KEAP1 mRNA CTD PMID:34993831 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Khdc4 KH domain containing 4, pre-mRNA splicing factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of KHDC4 mRNA CTD PMID:33854195 NCBI chr 2:174,149,059...174,177,816
Ensembl chr 2:174,149,141...174,177,504 		JBrowse link
G Klf10 KLF transcription factor 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of KLF10 mRNA CTD PMID:33854195 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994 		JBrowse link
G Klf2 KLF transcription factor 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of KLF2 mRNA CTD PMID:33854195 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klhl10 kelch-like family member 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of KLHL10 gene CTD PMID:33854195 NCBI chr10:85,376,442...85,392,720
Ensembl chr10:85,376,442...85,392,720 		JBrowse link
G Klk1 kallikrein 1 decreases expression EXP imidacloprid results in decreased expression of KLK1 mRNA CTD PMID:27782041 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754 		JBrowse link
G Krt5 keratin 5 decreases expression EXP imidacloprid results in decreased expression of KRT5 mRNA CTD PMID:27782041 NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850 		JBrowse link
G Lep leptin multiple interactions
increases secretion 		ISO Dietary Fats promotes the reaction [imidacloprid results in increased secretion of LEP protein]; imidacloprid promotes the reaction [Dietary Fats results in increased secretion of LEP protein] CTD PMID:27960282 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lgalsl galectin-like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LGALSL mRNA CTD PMID:33854195 NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases expression 		EXP Thymol inhibits the reaction [imidacloprid results in increased expression of LHB protein] CTD PMID:34171690 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lhx2 LIM homeobox 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of LHX2 gene CTD PMID:33854195 NCBI chr 3:22,113,619...22,143,909
Ensembl chr 3:22,126,007...22,143,908 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO LIF protein affects the reaction [imidacloprid affects the methylation of APC promoter]; LIF protein affects the reaction [imidacloprid affects the methylation of CDH1 promoter]; LIF protein affects the reaction [imidacloprid affects the methylation of CDKN2A promoter]; LIF protein affects the reaction [imidacloprid affects the methylation of MLH1 promoter]; LIF protein affects the reaction [imidacloprid affects the methylation of RARB promoter]; LIF protein affects the reaction [imidacloprid affects the methylation of TIMP3 promoter] CTD PMID:33865946 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lipe lipase E, hormone sensitive type increases expression ISO imidacloprid results in increased expression of LIPE mRNA CTD PMID:33487623 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310 		JBrowse link
G Litaf lipopolysaccharide-induced TNF factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LITAF mRNA CTD PMID:33854195 NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763 		JBrowse link
G Lnx2 ligand of numb-protein X 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LNX2 mRNA CTD PMID:33854195 NCBI chr12:13,119,139...13,184,401
Ensembl chr12:8,005,227...8,070,494 		JBrowse link
G Loxl3 lysyl oxidase-like 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LOXL3 gene CTD PMID:33854195 NCBI chr 4:115,540,640...115,556,958
Ensembl chr 4:115,540,685...115,557,466 		JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LPCAT1 gene CTD PMID:33854195 NCBI chr 1:31,594,621...31,644,946
Ensembl chr 1:29,766,071...29,816,401 		JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LPGAT1 gene CTD PMID:33854195 NCBI chr13:105,825,630...105,896,366
Ensembl chr13:103,294,528...103,362,333 		JBrowse link
G Lpin3 lipin 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of LPIN3 mRNA CTD PMID:33854195 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327 		JBrowse link
G Lta4h leukotriene A4 hydrolase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of LTA4H mRNA CTD PMID:33854195 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Lurap1l leucine rich adaptor protein 1-like multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of LURAP1L gene CTD PMID:33854195 NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438 		JBrowse link
G Lynx1 Ly6/neurotoxin 1 multiple interactions EXP LYNX1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr 7:106,632,800...106,638,003
Ensembl chr 7:106,632,797...106,638,023 		JBrowse link
G Lypd1 Ly6/Plaur domain containing 1 multiple interactions EXP LYPD1 protein promotes the reaction [imidacloprid results in increased activity of [CHRNA1 protein binds to CHRNB2 protein]] CTD PMID:19619141 NCBI chr13:37,326,459...37,368,515
Ensembl chr13:37,326,464...37,368,493 		JBrowse link
G Lyz2 lysozyme 2 multiple interactions
decreases activity 		EXP Plant Extracts inhibits the reaction [imidacloprid results in decreased activity of LYZ protein] CTD PMID:35398170 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Magel2 MAGE family member L2 increases expression EXP imidacloprid results in increased expression of MAGEL2 mRNA CTD PMID:27782041 NCBI chr 1:125,292,033...125,296,575
Ensembl chr 1:115,880,474...115,884,250 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO imidacloprid results in increased phosphorylation of MAPK1 protein CTD PMID:12460746 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO imidacloprid results in increased phosphorylation of MAPK3 protein CTD PMID:12460746 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases expression EXP imidacloprid results in increased expression of MAPK8 mRNA CTD PMID:34993831 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MAPKAPK2 mRNA CTD PMID:33854195 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Marf1 meiosis regulator and mRNA stability factor 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MARF1 mRNA CTD PMID:33854195 NCBI chr10:888,053...932,760
Ensembl chr10:888,076...932,753 		JBrowse link
G Mb myoglobin decreases expression EXP imidacloprid results in decreased expression of MB mRNA CTD PMID:27782041 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Med12l mediator complex subunit 12L multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MED12L mRNA CTD PMID:33854195 NCBI chr 2:143,253,048...143,576,507
Ensembl chr 2:143,252,139...143,573,741 		JBrowse link
G Mettl14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of METTL14 mRNA CTD PMID:33854195 NCBI chr 2:211,530,598...211,546,845
Ensembl chr 2:211,530,602...211,546,821 		JBrowse link
G Mfap5 microfibril associated protein 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of MFAP5 gene CTD PMID:33854195 NCBI chr 4:155,727,925...155,750,458
Ensembl chr 4:155,727,925...155,750,458 		JBrowse link
G Mif macrophage migration inhibitory factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIF mRNA CTD PMID:33854195 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Mir122 microRNA 122 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR122 mRNA CTD PMID:34626815 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir130a microRNA 130a multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR130A mRNA CTD PMID:34626815 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir146a microRNA 146a multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MIR146A mRNA CTD PMID:34626815 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir193 microRNA 193 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR193 mRNA CTD PMID:34626815 NCBI chr10:64,672,354...64,672,439 JBrowse link
G Mir22 microRNA 22 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR22 mRNA CTD PMID:34626815 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
G Mir32 microRNA 32 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR32 mRNA CTD PMID:34626815 NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152 		JBrowse link
G Mir33 microRNA 33 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MIR33 mRNA CTD PMID:34626815 NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923 		JBrowse link
G Mir486 microRNA 486 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MIR486 mRNA CTD PMID:34626815
G Mlh1 mutL homolog 1 multiple interactions
affects methylation 		ISO LIF protein affects the reaction [imidacloprid affects the methylation of MLH1 promoter] CTD PMID:33865946 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mlxipl MLX interacting protein-like increases expression ISO imidacloprid results in increased expression of MLXIPL mRNA CTD PMID:33487623 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112 		JBrowse link
G Mlycd malonyl-CoA decarboxylase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MLYCD mRNA CTD PMID:33854195 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MOCS2 mRNA CTD PMID:33854195 NCBI chr 2:46,504,588...46,516,327
Ensembl chr 2:46,504,588...46,516,324 		JBrowse link
G Morc3 MORC family CW-type zinc finger 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MORC3 mRNA CTD PMID:33854195 NCBI chr11:33,151,906...33,194,650
Ensembl chr11:33,152,025...33,194,646 		JBrowse link
G Mpo myeloperoxidase increases expression EXP imidacloprid results in increased expression of MPO protein CTD PMID:37648049 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mrgbp MRG domain binding protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MRGBP mRNA CTD PMID:33854195 NCBI chr 3:167,697,129...167,700,592
Ensembl chr 3:167,697,185...167,700,592 		JBrowse link
G Mrnip MRN complex interacting protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of MRNIP mRNA CTD PMID:33854195 NCBI chr10:34,501,359...34,525,474
Ensembl chr10:34,501,384...34,525,469 		JBrowse link
G Mrpl44 mitochondrial ribosomal protein L44 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MRPL44 mRNA CTD PMID:33854195 NCBI chr 9:81,106,658...81,111,709
Ensembl chr 9:81,106,655...81,112,812 		JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MRPS18B mRNA CTD PMID:33854195 NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260 		JBrowse link
G Mt1 metallothionein 1 increases expression EXP imidacloprid results in increased expression of MT1 mRNA CTD PMID:39002876 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt2 metallothionein 2 increases expression EXP imidacloprid results in increased expression of MT2A mRNA CTD PMID:39002876 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MTARC1 mRNA CTD PMID:33854195 NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796 		JBrowse link
G Mybpc2 myosin binding protein C2 increases expression EXP imidacloprid results in increased expression of MYBPC2 mRNA CTD PMID:27782041 NCBI chr 1:94,994,121...95,017,584
Ensembl chr 1:94,994,104...95,017,584 		JBrowse link
G Myo10 myosin X multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of MYO10 mRNA CTD PMID:33854195 NCBI chr 2:77,831,532...78,036,137
Ensembl chr 2:76,100,987...76,303,030 		JBrowse link
G Mypn myopalladin decreases expression EXP imidacloprid results in decreased expression of MYPN mRNA CTD PMID:27782041 NCBI chr20:25,429,898...25,522,443
Ensembl chr20:25,436,843...25,522,443 		JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of N4BP2L2 mRNA CTD PMID:33854195 NCBI chr12:137,342...200,292
Ensembl chr12:103,590...197,784 		JBrowse link
G Nae1 NEDD8 activating enzyme E1 subunit 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NAE1 mRNA CTD PMID:33854195 NCBI chr19:446,015...472,145
Ensembl chr19:446,000...472,371 		JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 decreases expression EXP imidacloprid results in decreased expression of NDUFAF2 mRNA CTD PMID:27782041 NCBI chr 2:39,535,680...39,647,378
Ensembl chr 2:39,535,689...39,647,316 		JBrowse link
G Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of NDUFB11 gene CTD PMID:33854195 NCBI chr  X:1,572,805...1,575,063
Ensembl chr  X:1,572,785...1,575,062 		JBrowse link
G Nes nestin decreases expression EXP imidacloprid results in decreased expression of NES mRNA CTD PMID:39002876 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Neurog3 neurogenin 3 decreases expression EXP imidacloprid results in decreased expression of NEUROG3 mRNA CTD PMID:27782041 NCBI chr20:30,079,780...30,081,262
Ensembl chr20:30,079,780...30,081,262 		JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NFE2 mRNA CTD PMID:33854195 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects expression EXP imidacloprid affects the expression of NFE2L2 mRNA CTD PMID:39002876 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of NFIL3 mRNA CTD PMID:33854195 NCBI chr17:12,432,376...12,447,605
Ensembl chr17:12,280,484...12,295,858 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression EXP imidacloprid results in increased expression of NFKB1 mRNA CTD PMID:39002876 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR0B2 mRNA CTD PMID:33854195 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR1D1 mRNA CTD PMID:33854195 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of NR1D2 mRNA CTD PMID:33854195 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO imidacloprid results in increased expression of NR1I2 mRNA CTD PMID:33487623 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 decreases abundance ISO NR1I3 results in decreased abundance of imidacloprid CTD PMID:36320626 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression EXP imidacloprid results in decreased expression of NR5A1 mRNA CTD PMID:27914857 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression EXP imidacloprid results in increased expression of NTRK2 mRNA CTD PMID:39002876 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of NUCKS1 mRNA CTD PMID:33854195 NCBI chr13:43,345,091...43,374,316
Ensembl chr13:43,345,115...43,370,229 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression EXP imidacloprid results in increased expression of OASL mRNA CTD PMID:27782041 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression EXP imidacloprid results in increased expression of OGG1 mRNA CTD PMID:27914857 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Olr943 olfactory receptor 943 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of OLR943 gene CTD PMID:33854195 NCBI chr 7:3,389,336...3,390,274
Ensembl chr 7:3,388,200...3,392,130 		JBrowse link
G Oplah 5-oxoprolinase (ATP-hydrolysing) multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of OPLAH mRNA CTD PMID:33854195 NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297 		JBrowse link
G Orai3 ORAI calcium release-activated calcium modulator 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of ORAI3 gene CTD PMID:33854195 NCBI chr 1:182,381,196...182,386,055
Ensembl chr 1:182,344,293...182,386,052 		JBrowse link
G Pabir1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PABIR1 gene CTD PMID:33854195 NCBI chr 1:222,114,988...222,116,294
Ensembl chr 1:222,112,591...222,116,396 		JBrowse link
G Parpbp PARP1 binding protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of PARPBP gene CTD PMID:33854195 NCBI chr 7:22,511,427...22,580,834
Ensembl chr 7:22,511,427...22,573,695 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression
multiple interactions 		ISO imidacloprid results in increased expression of PCK2 mRNA
Dietary Fats promotes the reaction [imidacloprid results in increased expression of PCK2 mRNA]; imidacloprid promotes the reaction [Dietary Fats results in increased expression of PCK2 mRNA] 		CTD PMID:27960282 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions
decreases expression 		EXP Thymol inhibits the reaction [imidacloprid results in decreased expression of PCNA protein]
imidacloprid results in decreased expression of PCNA mRNA; imidacloprid results in decreased expression of PCNA protein 		CTD PMID:34171690 PMID:39002876 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO imidacloprid results in increased expression of PDK4 mRNA CTD PMID:27960282 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PDLIM1 mRNA CTD PMID:33854195 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076 		JBrowse link
G Pdp1 pyruvate dehydrogenase phosphatase catalytic subunit 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PDP1 mRNA CTD PMID:33854195 NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217 		JBrowse link
G Pdzd2 PDZ domain containing 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PDZD2 gene CTD PMID:33854195 NCBI chr 2:61,384,614...61,770,516
Ensembl chr 2:61,386,381...61,770,524 		JBrowse link
G Per1 period circadian regulator 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PER1 mRNA CTD PMID:33854195 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Per3 period circadian regulator 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PER3 mRNA CTD PMID:33854195 NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PGK1 mRNA CTD PMID:33854195 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pgr progesterone receptor affects expression ISO imidacloprid affects the expression of PGR mRNA CTD PMID:35457321 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIAS3 mRNA CTD PMID:33854195 NCBI chr 2:186,921,384...186,930,292
Ensembl chr 2:184,232,571...184,241,480 		JBrowse link
G Pip4p1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PIP4P1 mRNA CTD PMID:33854195 NCBI chr15:24,146,854...24,150,739
Ensembl chr15:24,146,856...24,150,702 		JBrowse link
G Pirb paired Ig-like receptor B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of LILRB3 mRNA CTD PMID:33854195 NCBI chr 1:65,499,195...65,506,666
Ensembl chr 1:65,499,195...65,506,666 		JBrowse link
G Plekhg5 pleckstrin homology and RhoGEF domain containing G5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PLEKHG5 mRNA CTD PMID:33854195 NCBI chr 5:162,577,999...162,621,518
Ensembl chr 5:162,578,071...162,621,513 		JBrowse link
G Plk2 polo-like kinase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PLK2 mRNA CTD PMID:33854195 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947 		JBrowse link
G Plpp4 phospholipid phosphatase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PLPP4 gene CTD PMID:33854195 NCBI chr 1:183,829,794...183,959,319
Ensembl chr 1:183,830,409...183,959,319 		JBrowse link
G Pmvk phosphomevalonate kinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PMVK mRNA CTD PMID:33854195 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364 		JBrowse link
G Pnkd PNKD metallo-beta-lactamase domain containing multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PNKD mRNA CTD PMID:33854195 NCBI chr 9:75,868,620...75,937,126
Ensembl chr 9:75,867,468...75,937,124 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase multiple interactions
increases expression 		EXP imidacloprid promotes the reaction [Nicotine results in increased expression of PNMT protein]
imidacloprid results in increased expression of PNMT protein 		CTD PMID:29246838 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 increases expression ISO imidacloprid results in increased expression of PNPLA2 mRNA CTD PMID:33487623 NCBI chr 1:205,982,279...205,987,361
Ensembl chr 1:196,552,723...196,557,805 		JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PNRC1 mRNA CTD PMID:33854195 NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161 		JBrowse link
G Por cytochrome p450 oxidoreductase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of POR gene CTD PMID:33854195 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
increases expression 		ISO imidacloprid results in decreased expression of PPARA mRNA
imidacloprid results in increased expression of PPARA mRNA 		CTD PMID:27960282 PMID:33487623 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PPARD mRNA CTD PMID:33854195 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression ISO imidacloprid results in decreased expression of PPARGC1A protein CTD PMID:27960282 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prdm15 PR/SET domain 15 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRDM15 mRNA CTD PMID:33854195 NCBI chr11:37,164,608...37,225,172
Ensembl chr11:37,165,575...37,222,207 		JBrowse link
G Prelid2 PRELI domain containing 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PRELID2 mRNA CTD PMID:33854195 NCBI chr18:33,869,934...33,961,320
Ensembl chr18:33,873,599...33,961,225 		JBrowse link
G Prelp proline and arginine rich end leucine rich repeat protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PRELP mRNA CTD PMID:33854195 NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270 		JBrowse link
G Prl prolactin multiple interactions ISO [mancozeb co-treated with imidacloprid] results in increased expression of PRL protein CTD PMID:24530807 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Proser2 proline and serine rich 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PROSER2 mRNA CTD PMID:33854195 NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825 		JBrowse link
G Prpf39 pre-mRNA processing factor 39 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PRPF39 mRNA CTD PMID:33854195 NCBI chr 6:83,088,981...83,113,826
Ensembl chr 6:83,088,986...83,113,825 		JBrowse link
G Prss3b protease, serine, 3B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of PRSS3B gene CTD PMID:33854195 NCBI chr 4:69,871,810...69,875,518
Ensembl chr 4:69,871,797...69,875,549 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC2 mRNA CTD PMID:33854195 NCBI chr 4:13,255,850...13,270,160
Ensembl chr 4:13,255,856...13,270,185 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC4 mRNA CTD PMID:33854195 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PSMC5 mRNA CTD PMID:33854195 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP imidacloprid results in increased expression of PTGS2 mRNA CTD PMID:39002876 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptpa protein phosphatase 2 phosphatase activator multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of PTPA mRNA CTD PMID:33854195 NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549 		JBrowse link
G Pus10 pseudouridine synthase 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of PUS10 mRNA CTD PMID:33854195 NCBI chr14:97,621,228...97,684,059
Ensembl chr14:97,621,391...97,684,046 		JBrowse link
G Rabep1 rabaptin, RAB GTPase binding effector protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABEP1 mRNA CTD PMID:33854195 NCBI chr10:55,566,156...55,667,595
Ensembl chr10:55,566,185...55,665,973 		JBrowse link
G Rabl2 RAB, member of RAS oncogene family like 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RABL2 mRNA CTD PMID:33854195 NCBI chr 7:120,652,175...120,660,906
Ensembl chr 7:120,652,175...120,660,783 		JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RAMAC gene CTD PMID:33854195 NCBI chr 1:135,708,529...135,714,417
Ensembl chr 1:135,708,535...135,722,151 		JBrowse link
G Rangap1 RAN GTPase activating protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RANGAP1 mRNA CTD PMID:33854195 NCBI chr 7:115,104,820...115,130,564
Ensembl chr 7:113,224,703...113,250,438 		JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions
affects methylation 		ISO LIF protein affects the reaction [imidacloprid affects the methylation of RARB promoter] CTD PMID:33865946 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rars1 arginyl-tRNA synthetase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RARS1 mRNA CTD PMID:33854195 NCBI chr10:20,270,744...20,295,192
Ensembl chr10:20,270,483...20,295,196 		JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 increases expression EXP imidacloprid results in increased expression of RBFOX2 mRNA CTD PMID:27782041 NCBI chr 7:108,810,627...109,054,420
Ensembl chr 7:108,810,628...109,054,691 		JBrowse link
G Rbm14 RNA binding motif protein 14 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RBM14 mRNA CTD PMID:33854195 NCBI chr 1:202,076,940...202,105,688
Ensembl chr 1:202,078,287...202,105,665
Ensembl chr 1:202,078,287...202,105,665 		JBrowse link
G Rbm3 RNA binding motif protein 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RBM3 mRNA CTD PMID:33854195 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580 		JBrowse link
G Rbpms RNA binding protein, mRNA processing factor multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RBPMS gene CTD PMID:33854195 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP imidacloprid results in increased expression of RELA protein CTD PMID:37648049 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Resf1 retroelement silencing factor 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RESF1 mRNA CTD PMID:33854195 NCBI chr 4:182,325,913...182,362,054
Ensembl chr 4:182,335,454...182,362,054 		JBrowse link
G Rev1 REV1, DNA directed polymerase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of REV1 mRNA CTD PMID:33854195 NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576 		JBrowse link
G Rfx7 regulatory factor X, 7 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RFX7 mRNA CTD PMID:33854195 NCBI chr 8:73,254,051...73,339,209
Ensembl chr 8:73,254,051...73,339,209 		JBrowse link
G Rgcc regulator of cell cycle multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RGCC gene CTD PMID:33854195 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RGS16 mRNA CTD PMID:33854195 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857 		JBrowse link
G Rhobtb3 Rho-related BTB domain containing 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RHOBTB3 mRNA CTD PMID:33854195 NCBI chr 2:5,363,388...5,419,164
Ensembl chr 2:5,363,388...5,419,041 		JBrowse link
G Rnase10 ribonuclease A family member 10 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of RNASE10 gene CTD PMID:33854195 NCBI chr15:24,226,687...24,229,149
Ensembl chr15:24,226,691...24,228,561 		JBrowse link
G Rnd3 Rho family GTPase 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of RND3 gene; [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of RND3 mRNA CTD PMID:33854195 NCBI chr 3:55,981,142...55,998,494
Ensembl chr 3:35,571,143...35,589,327 		JBrowse link
G Rorc RAR-related orphan receptor C multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of RORC mRNA CTD PMID:33854195 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907 		JBrowse link
G Rxylt1 ribitol xylosyltransferase 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of RXYLT1 gene CTD PMID:33854195 NCBI chr 7:59,656,274...59,668,140
Ensembl chr 7:57,770,842...57,782,657 		JBrowse link
G Sall4 spalt-like transcription factor 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SALL4 gene CTD PMID:33854195 NCBI chr 3:157,474,067...157,491,055
Ensembl chr 3:157,474,642...157,490,822 		JBrowse link
G Sardh sarcosine dehydrogenase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SARDH mRNA CTD PMID:33854195 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874 		JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SCNN1A mRNA CTD PMID:33854195 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181 		JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SDR42E1 mRNA CTD PMID:33854195 NCBI chr19:45,715,366...45,727,901
Ensembl chr19:45,715,399...45,727,901 		JBrowse link
G Serpina1 serpin family A member 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SERPINA1 mRNA CTD PMID:33854195 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Sesn2 sestrin 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SESN2 mRNA CTD PMID:33854195 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Setd6 SET domain containing 6, protein lysine methyltransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SETD6 mRNA CTD PMID:33854195 NCBI chr19:9,343,309...9,350,477
Ensembl chr19:9,347,458...9,350,453 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of SFRP2 gene CTD PMID:33854195 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sh3bp2 SH3-domain binding protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SH3BP2 mRNA CTD PMID:33854195 NCBI chr14:76,176,097...76,213,300
Ensembl chr14:76,176,101...76,213,251 		JBrowse link
G Sigirr single Ig and TIR domain containing multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SIGIRR mRNA CTD PMID:33854195 NCBI chr 1:196,195,363...196,208,692
Ensembl chr 1:196,199,462...196,202,269 		JBrowse link
G Sik2 salt-inducible kinase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SIK2 mRNA CTD PMID:33854195 NCBI chr 8:51,225,543...51,325,343
Ensembl chr 8:51,225,543...51,325,415 		JBrowse link
G Sirt1 sirtuin 1 decreases expression ISO imidacloprid results in decreased expression of SIRT1 protein CTD PMID:27960282 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc12a6 solute carrier family 12, member 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC12A6 mRNA CTD PMID:33854195 NCBI chr 3:99,071,577...99,170,266
Ensembl chr 3:99,071,391...99,170,258 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC20A1 mRNA CTD PMID:33854195 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases activity ISO imidacloprid results in increased activity of SLC22A1 protein CTD PMID:31364238 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases activity ISO imidacloprid results in decreased activity of SLC22A2 protein CTD PMID:31364238 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a8 solute carrier family 22 member 8 decreases activity ISO imidacloprid results in decreased activity of SLC22A8 protein CTD PMID:31364238 NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450 		JBrowse link
G Slc25a39 solute carrier family 25, member 39 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SLC25A39 mRNA CTD PMID:33854195 NCBI chr10:87,362,494...87,367,358
Ensembl chr10:87,362,490...87,367,260 		JBrowse link
G Slc26a6 solute carrier family 26 member 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SLC26A6 mRNA CTD PMID:33854195 NCBI chr 8:109,558,968...109,569,778
Ensembl chr 8:109,559,642...109,569,778 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 increases expression EXP imidacloprid results in increased expression of SLC2A2 mRNA CTD PMID:28850943 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression EXP imidacloprid results in increased expression of SLC2A3 mRNA CTD PMID:27782041 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO
EXP 		imidacloprid results in decreased expression of SLC2A4 mRNA
imidacloprid results in decreased expression of SLC2A4 mRNA; imidacloprid results in decreased expression of SLC2A4 protein 		CTD PMID:27960282 PMID:28850943 PMID:32685429 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc37a2 solute carrier family 37 member 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SLC37A2 mRNA CTD PMID:33854195 NCBI chr 8:36,945,787...36,971,748
Ensembl chr 8:36,946,930...36,971,482 		JBrowse link
G Slk STE20-like kinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SLK gene CTD PMID:33854195 NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530 		JBrowse link
G Smad7 SMAD family member 7 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SMAD7 mRNA CTD PMID:33854195 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smpx small muscle protein, X-linked multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SMPX gene CTD PMID:33854195 NCBI chr  X:37,233,209...37,292,266
Ensembl chr  X:37,234,294...37,276,708 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SNRNP200 mRNA CTD PMID:33854195 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Snx4 sorting nexin 4 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SNX4 mRNA CTD PMID:33854195 NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SOCS3 mRNA CTD PMID:33854195 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [imidacloprid co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA CTD PMID:33487623 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SOD3 mRNA CTD PMID:33854195 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sohlh1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of SOHLH1 gene CTD PMID:33854195 NCBI chr 3:8,662,995...8,667,521
Ensembl chr 3:8,663,318...8,667,388 		JBrowse link
G Spag1 sperm associated antigen 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SPAG1 mRNA CTD PMID:33854195 NCBI chr 7:67,361,474...67,421,369
Ensembl chr 7:67,361,477...67,421,368 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of SRD5A2 gene CTD PMID:33854195 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO imidacloprid results in increased expression of SREBF1 mRNA CTD PMID:27960282 PMID:33487623 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 increases expression
multiple interactions 		ISO imidacloprid results in increased expression of SREBF2 mRNA
[imidacloprid co-treated with Dietary Fats] results in increased expression of SREBF2 mRNA 		CTD PMID:33487623 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SRRM2 mRNA CTD PMID:33854195 NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SRSF5 mRNA CTD PMID:33854195 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions 		ISO
EXP 		imidacloprid results in decreased expression of STAR mRNA
Thymol inhibits the reaction [imidacloprid results in decreased expression of STAR mRNA] 		CTD PMID:31780179 PMID:34171690 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stard9 StAR-related lipid transfer domain containing 9 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of STARD9 mRNA CTD PMID:33854195 NCBI chr 3:107,581,097...107,672,746
Ensembl chr 3:107,581,164...107,673,898 		JBrowse link
G Susd2 sushi domain containing 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SUSD2 mRNA CTD PMID:33854195 NCBI chr20:13,017,516...13,024,820
Ensembl chr20:13,017,477...13,024,903 		JBrowse link
G Sympk symplekin scaffold protein multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of SYMPK mRNA CTD PMID:33854195 NCBI chr 1:78,672,372...78,700,684
Ensembl chr 1:78,672,378...78,700,684 		JBrowse link
G Tacr3 tachykinin receptor 3 increases expression EXP imidacloprid results in increased expression of TACR3 mRNA CTD PMID:27782041 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
G Tada2b transcriptional adaptor 2B increases expression EXP imidacloprid results in increased expression of TADA2B mRNA CTD PMID:27782041 NCBI chr14:74,279,286...74,290,758
Ensembl chr14:74,279,217...74,290,755 		JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TAT mRNA CTD PMID:33854195 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tdp2 tyrosyl-DNA phosphodiesterase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TDP2 mRNA CTD PMID:33854195 NCBI chr17:40,228,943...40,240,337
Ensembl chr17:40,228,947...40,240,313 		JBrowse link
G Tead2 TEA domain transcription factor 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TEAD2 mRNA CTD PMID:33854195 NCBI chr 1:95,702,366...95,719,186
Ensembl chr 1:95,703,005...95,719,186 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TECR mRNA CTD PMID:33854195 NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168 		JBrowse link
G Tfap2a transcription factor AP-2 alpha multiple interactions ISO [imidacloprid co-treated with Dietary Fats] results in decreased expression of TFAP2A mRNA CTD PMID:33487623 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tgds TDP-glucose 4,6-dehydratase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TGDS mRNA CTD PMID:33854195 NCBI chr15:95,175,064...95,195,555
Ensembl chr15:95,174,608...95,195,554 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 affects expression EXP imidacloprid affects the expression of TGFB1 mRNA CTD PMID:39002876 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbi transforming growth factor, beta induced multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TGFBI mRNA CTD PMID:33854195 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
increases expression 		EXP [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; [conotoxin AuIB co-treated with triethyl-(beta-4-stilbenoxyethyl)ammonium co-treated with ZM 241385] inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; [N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide co-treated with exoenzyme C3, Clostridium botulinum] inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; conotoxin AuIB inhibits the reaction [imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]]; conotoxin AuIB inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; conotoxin AuIB inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; exoenzyme C3, Clostridium botulinum inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]; imidacloprid promotes the reaction [Nicotine results in increased expression of TH protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid promotes the reaction [Acetylcholine results in increased expression of TH mRNA]]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; triethyl-(beta-4-stilbenoxyethyl)ammonium inhibits the reaction [imidacloprid results in increased expression of TH mRNA]; ZM 241385 inhibits the reaction [imidacloprid promotes the reaction [Nicotine results in increased expression of TH mRNA]]; ZM 241385 inhibits the reaction [imidacloprid results in increased expression of TH mRNA]
imidacloprid results in increased expression of TH mRNA; imidacloprid results in increased expression of TH protein 		CTD PMID:29246838 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thrb thyroid hormone receptor beta affects binding ISO imidacloprid binds to THRB protein CTD PMID:28973306 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 affects methylation
multiple interactions 		ISO imidacloprid affects the methylation of TIMP3 promoter
LIF protein affects the reaction [imidacloprid affects the methylation of TIMP3 promoter] 		CTD PMID:33865946 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tjap1 tight junction associated protein 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TJAP1 mRNA CTD PMID:33854195 NCBI chr 9:14,701,418...14,725,623
Ensembl chr 9:14,701,468...14,725,751 		JBrowse link
G Tjp1 tight junction protein 1 decreases expression EXP imidacloprid results in decreased expression of TJP1 mRNA CTD PMID:27792329 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tk1 thymidine kinase 1 increases mutagenesis ISO imidacloprid results in increased mutagenesis of TK1 gene CTD PMID:30103639 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Tkt transketolase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TKT mRNA CTD PMID:33854195 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TMBIM6 mRNA CTD PMID:33854195 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Tmem268 transmembrane protein 268 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TMEM268 mRNA CTD PMID:33854195 NCBI chr 5:76,974,827...77,001,457
Ensembl chr 5:76,977,310...77,001,452 		JBrowse link
G Tmt1b thiol methyltransferase 1B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TMT1B mRNA CTD PMID:33854195 NCBI chr 7:1,388,876...1,391,526
Ensembl chr 7:1,388,879...1,391,526 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression 		ISO
EXP 		Dietary Fats promotes the reaction [imidacloprid results in increased expression of TNF mRNA]; imidacloprid promotes the reaction [Dietary Fats results in increased expression of TNF mRNA]
imidacloprid results in increased expression of TNF mRNA; imidacloprid results in increased expression of TNF protein
Plant Extracts inhibits the reaction [imidacloprid results in increased expression of TNF mRNA] 		CTD PMID:27960282 PMID:34993831 PMID:35398170 PMID:39002876 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip2 TNF alpha induced protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TNFAIP2 mRNA CTD PMID:33854195 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914 		JBrowse link
G Tnni2 troponin I2, fast skeletal type decreases expression EXP imidacloprid results in decreased expression of TNNI2 mRNA CTD PMID:27782041 NCBI chr 1:197,595,012...197,597,554
Ensembl chr 1:197,594,813...197,597,560 		JBrowse link
G Tor3a torsin family 3, member A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TOR3A mRNA CTD PMID:33854195 NCBI chr13:68,769,893...68,798,738
Ensembl chr13:68,769,605...68,798,475 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAF3IP2 mRNA CTD PMID:33854195 NCBI chr20:44,565,992...44,609,240
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRAFD1 mRNA CTD PMID:33854195 NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525 		JBrowse link
G Trim34 tripartite motif-containing 34 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of TRIM34 mRNA CTD PMID:33854195 NCBI chr 1:168,119,043...168,130,544
Ensembl chr 1:158,707,172...158,718,674 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of TSC22D3 mRNA CTD PMID:33854195 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [mancozeb co-treated with imidacloprid] results in increased expression of TSHB protein CTD PMID:24530807 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Tspo translocator protein decreases expression ISO imidacloprid results in decreased expression of TSPO mRNA CTD PMID:31780179 NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression EXP imidacloprid results in decreased expression of TUBB3 mRNA CTD PMID:39002876 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243 		JBrowse link
G Txk TXK tyrosine kinase increases expression EXP imidacloprid results in increased expression of TXK mRNA CTD PMID:27782041 NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448 		JBrowse link
G Uba3 ubiquitin-like modifier activating enzyme 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of UBA3 mRNA CTD PMID:33854195 NCBI chr 4:129,789,526...129,810,707
Ensembl chr 4:129,789,204...129,810,606 		JBrowse link
G Ubb ubiquitin B multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UBB mRNA CTD PMID:33854195 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
G Ubc ubiquitin C multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UBC mRNA CTD PMID:33854195 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Uckl1 uridine-cytidine kinase 1-like 1 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of UCKL1 mRNA CTD PMID:33854195 NCBI chr 3:168,674,849...168,687,513
Ensembl chr 3:168,674,849...168,698,091 		JBrowse link
G Unc45a unc-45 myosin chaperone A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UNC45A mRNA CTD PMID:33854195 NCBI chr 1:134,281,930...134,296,661
Ensembl chr 1:134,281,933...134,301,586 		JBrowse link
G Unc45b unc-45 myosin chaperone B decreases expression EXP imidacloprid results in decreased expression of UNC45B mRNA CTD PMID:27782041 NCBI chr10:67,845,464...67,873,143
Ensembl chr10:67,845,462...67,873,389 		JBrowse link
G Uox urate oxidase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of UOX mRNA CTD PMID:33854195 NCBI chr 2:235,486,867...235,523,053
Ensembl chr 2:235,440,619...235,523,029 		JBrowse link
G Usp2 ubiquitin specific peptidase 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of USP2 mRNA CTD PMID:33854195 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331 		JBrowse link
G Usp40 ubiquitin specific peptidase 40 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of USP40 mRNA CTD PMID:33854195 NCBI chr 9:88,607,920...88,678,940
Ensembl chr 9:88,607,930...88,678,914 		JBrowse link
G Vcl vinculin decreases expression EXP imidacloprid results in decreased expression of VCL mRNA CTD PMID:27792329 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of VEGFA mRNA CTD PMID:33854195 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vldlr very low density lipoprotein receptor increases expression EXP imidacloprid results in increased expression of VLDLR mRNA CTD PMID:39002876 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
G Vnn3 vanin 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of VNN3 mRNA CTD PMID:33854195 NCBI chr 1:21,571,364...21,583,626
Ensembl chr 1:21,571,364...21,583,626 		JBrowse link
G Vtn vitronectin multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of VTN mRNA CTD PMID:33854195 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810 		JBrowse link
G Wdr11 WD repeat domain 11 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of WDR11 gene CTD PMID:33854195 NCBI chr 1:184,165,260...184,210,834
Ensembl chr 1:184,165,571...184,210,846 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased expression of WEE1 mRNA CTD PMID:33854195 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688 		JBrowse link
G Wfdc9 WAP four-disulfide core domain 9 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased methylation of WFDC9 gene CTD PMID:33854195 NCBI chr 3:153,380,554...153,389,055
Ensembl chr 3:153,380,649...153,391,261 		JBrowse link
G Yod1 YOD1 deubiquitinase multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in decreased methylation of YOD1 gene CTD PMID:33854195 NCBI chr13:42,175,047...42,181,661
Ensembl chr13:42,174,820...42,177,205 		JBrowse link
G Zfc3h1 zinc finger, C3H1-type containing multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFC3H1 mRNA CTD PMID:33854195 NCBI chr 7:51,008,251...51,064,666
Ensembl chr 7:51,007,984...51,064,661 		JBrowse link
G Zfp280d zinc finger protein 280D multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP280D mRNA CTD PMID:33854195 NCBI chr 8:72,992,655...73,080,482
Ensembl chr 8:72,992,650...73,080,480 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP36L2 mRNA CTD PMID:33854195 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064 		JBrowse link
G Zfp422 zinc finger protein 422 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP422 mRNA CTD PMID:33854195 NCBI chr 4:149,885,805...149,893,287
Ensembl chr 4:149,885,600...149,893,257 		JBrowse link
G Zfp455 zinc finger protein 455 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP455 mRNA CTD PMID:33854195 NCBI chr 2:84,712,431...84,733,542
Ensembl chr 2:84,718,482...84,733,538 		JBrowse link
G Zfp598 zinc finger protein 598 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZFP598 mRNA CTD PMID:33854195 NCBI chr10:14,198,763...14,210,773
Ensembl chr10:13,694,286...13,706,233 		JBrowse link
G Zmym3 zinc finger MYM-type containing 3 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZMYM3 mRNA CTD PMID:33854195 NCBI chr  X:66,528,585...66,544,234
Ensembl chr  X:66,528,585...66,544,782 		JBrowse link
G Zmym6 zinc finger MYM-type containing 6 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZMYM6 mRNA CTD PMID:33854195 NCBI chr 5:139,396,374...139,444,357
Ensembl chr 5:139,396,727...139,444,279 		JBrowse link
G Zranb2 zinc finger RANBP2-type containing 2 multiple interactions EXP [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of ZRANB2 mRNA CTD PMID:33854195 NCBI chr 2:246,573,110...246,586,942
Ensembl chr 2:246,573,166...246,586,942 		JBrowse link
imidapril term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 increases response to substance ISO ACE2 gene SNP results in increased susceptibility to imidapril CTD PMID:27121444 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO CES1 protein results in increased hydrolysis of and results in increased activity of imidapril; CES1 protein results in increased metabolism of and results in increased activity of imidapril; Dust inhibits the reaction [CES1 protein results in increased metabolism of and results in increased activity of imidapril]; tert-butylphenyl diphenyl phosphate inhibits the reaction [CES1 protein results in increased metabolism of and results in increased activity of imidapril]; triphenyl phosphate inhibits the reaction [CES1 protein results in increased metabolism of and results in increased activity of imidapril] CTD PMID:9300133 PMID:31268531 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 affects response to substance ISO CYP11B2 gene polymorphism affects the susceptibility to imidapril CTD PMID:16765146 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048 		JBrowse link
imidaprilat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions ISO imidaprilat inhibits the reaction [AGT protein results in increased activity of and results in increased localization of PRKCA protein] CTD PMID:16257180 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Prkca protein kinase C, alpha multiple interactions ISO imidaprilat inhibits the reaction [AGT protein results in increased activity of and results in increased localization of PRKCA protein] CTD PMID:16257180 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
imiprothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases expression EXP imiprothrin results in decreased expression of CAT protein CTD PMID:33638779 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP imiprothrin results in increased expression of CYP1A2 mRNA CTD PMID:33638779 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP imiprothrin results in increased expression of GPT protein CTD PMID:33638779 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Mt1 metallothionein 1 increases expression EXP imiprothrin results in increased expression of MT1 mRNA CTD PMID:33638779 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
iprodione term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO
EXP 		iprodione binds to and results in increased activity of AHR protein CTD PMID:14636698 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of ALDH2 mRNA; [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in decreased expression of and results in decreased activity of ALDH2 protein CTD PMID:34830855 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Anxa10 annexin A10 increases expression ISO iprodione results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:27,738,712...27,805,648
Ensembl chr16:27,738,712...27,805,648 		JBrowse link
G Ar androgen receptor multiple interactions
affects binding 		ISO [iprodione binds to and results in decreased activity of AR protein] inhibits the reaction [Metribolone binds to AR protein]; iprodione inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; iprodione inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein]
iprodione binds to AR protein 		CTD PMID:19564212 PMID:33049310 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions 		EXP iprodione results in decreased expression of BCL2 protein
Chlorpyrifos promotes the reaction [iprodione results in decreased expression of BCL2 protein]; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of BCL2 protein] 		CTD PMID:33586219 PMID:34060014 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions 		EXP iprodione results in increased expression of CASP3 protein
Chlorpyrifos promotes the reaction [iprodione results in increased expression of CASP3 protein]; iprodione promotes the reaction [Chlorpyrifos results in increased expression of CASP3 protein] 		CTD PMID:33586219 PMID:34060014 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin co-treated with 4-hydroxy-2-nonenal] results in decreased expression of CDH1 protein; [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in decreased expression of CDH1 protein CTD PMID:34503147 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cldn11 claudin 11 increases expression
multiple interactions 		EXP iprodione results in increased expression of CLDN11 protein
[carbendazim co-treated with iprodione] results in decreased expression of CLDN11 protein 		CTD PMID:28576679 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity ISO iprodione results in increased activity of CYP19A1 protein CTD PMID:11884232 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO iprodione results in increased expression of CYP1A1 mRNA; iprodione results in increased expression of CYP1A1 protein CTD PMID:16696176 PMID:32194361 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases expression ISO iprodione results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased expression of CYP3A4 mRNA CTD PMID:25028461 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO iprodione results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO iprodione results in increased expression of DDIT3 mRNA CTD PMID:16696176 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO iprodione binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO iprodione binds to and results in increased activity of ESR2 protein CTD PMID:33049310 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO iprodione results in increased expression of FOS mRNA CTD PMID:16696176 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions
decreases expression 		EXP Chlorpyrifos inhibits the reaction [iprodione results in decreased expression of FSHB protein]; iprodione inhibits the reaction [Chlorpyrifos results in decreased expression of FSHB protein]; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of FSHB protein] CTD PMID:33586219 PMID:34060014 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO iprodione results in increased expression of GADD45A mRNA CTD PMID:16696176 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP [carbendazim co-treated with iprodione] results in decreased expression of GJA1 protein CTD PMID:28576679 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO iprodione results in increased expression of GSTA2 mRNA CTD PMID:16696176 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [fludioxonil co-treated with cyprodinil co-treated with procymidone co-treated with iprodione co-treated with cyhalothrin] results in increased phosphorylation of H2AX protein; [Maneb co-treated with mancozeb co-treated with iprodione co-treated with enilconazole co-treated with Chlorpyrifos co-treated with Diazinon co-treated with Dimethoate] results in increased expression of H2AX protein; [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin co-treated with 4-hydroxy-2-nonenal] results in increased expression of H2AX protein; [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased expression of H2AX protein CTD PMID:22389207 PMID:34503147 PMID:34830855 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions
decreases expression 		EXP [Chlorpyrifos co-treated with iprodione] results in decreased expression of HSD17B3 mRNA; [iprodione co-treated with Chlorpyrifos] results in decreased expression of HSD17B3 mRNA
iprodione results in decreased expression of HSD17B3 mRNA 		CTD PMID:33586219 PMID:34060014 NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO iprodione results in increased expression of HSPA5 mRNA CTD PMID:16696176 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
decreases expression 		EXP Chlorpyrifos inhibits the reaction [iprodione results in decreased expression of LHB protein]; iprodione inhibits the reaction [Chlorpyrifos results in decreased expression of LHB protein] CTD PMID:34060014 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] results in increased activity of NR1I2 protein; iprodione binds to and results in increased activity of NR1I2 protein CTD PMID:25028461 PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression
multiple interactions 		EXP iprodione results in decreased expression of NR5A1 mRNA
[iprodione co-treated with Chlorpyrifos] results in decreased expression of NR5A1 mRNA; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of NR5A1 mRNA] 		CTD PMID:33586219 PMID:34060014 NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases activity
multiple interactions 		ISO iprodione results in increased activity of PPARG protein
iprodione binds to and results in increased activity of PPARG protein 		CTD PMID:20143881 PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression
multiple interactions 		EXP iprodione results in decreased expression of PPARGC1A mRNA
Chlorpyrifos promotes the reaction [iprodione results in decreased expression of PPARGC1A mRNA]; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of PPARGC1A mRNA] 		CTD PMID:33586219 PMID:34060014 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression 		EXP [iprodione co-treated with Chlorpyrifos] results in decreased expression of SIRT1 mRNA; iprodione promotes the reaction [Chlorpyrifos results in decreased expression of SIRT1 mRNA]
iprodione results in decreased expression of SIRT1 mRNA 		CTD PMID:33586219 PMID:34060014 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Stmn1 stathmin 1 increases expression EXP iprodione results in increased expression of STMN1 mRNA CTD PMID:28576679 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Tert telomerase reverse transcriptase multiple interactions
decreases expression 		EXP [Chlorpyrifos co-treated with iprodione] results in decreased expression of TERT mRNA; [iprodione co-treated with Chlorpyrifos] results in decreased expression of TERT mRNA
iprodione results in decreased expression of TERT mRNA 		CTD PMID:33586219 PMID:34060014 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO iprodione binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO iprodione binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Acetylcysteine inhibits the reaction [iprodione inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; iprodione inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:33226166 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 multiple interactions ISO [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin co-treated with 4-hydroxy-2-nonenal] affects the expression of TP53BP1 protein; [procymidone co-treated with iprodione co-treated with cyprodinil co-treated with fludioxonil co-treated with cyhalothrin] affects the expression of TP53BP1 protein CTD PMID:34503147 NCBI chr 3:108,166,574...108,270,229
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
mephenytoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Mephenytoin results in decreased activity of CYP1B1 protein CTD PMID:18420780 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases activity ISO Mephenytoin results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases methylation
decreases activity
multiple interactions
increases metabolic processing 		ISO CYP2B6 protein results in decreased methylation of Mephenytoin
Mephenytoin results in decreased activity of CYP2B10 protein
Mephenytoin results in decreased activity of CYP2B6 protein
Mephenytoin inhibits the reaction [[isoimperatorin co-treated with NADP] results in decreased activity of CYP2B6 protein]; Mephenytoin inhibits the reaction [CYP2B6 protein results in decreased ethylation of 7-ethoxy-4-trifluoromethylcoumarin]; Mephenytoin inhibits the reaction [CYP2B6 protein results in increased chemical synthesis of 7-hydroxy-4-trifluoromethylcoumarin]
CYP2B6 protein results in increased metabolism of Mephenytoin 		CTD PMID:9241656 PMID:12433797 PMID:12464242 PMID:18420780 PMID:25500267 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
decreases activity
increases metabolic processing
increases oxidation
affects hydroxylation
affects metabolic processing
increases hydroxylation 		ISO 4-amino-2-phenoxymethanesulfonanilide inhibits the reaction [CYP2C19 protein results in increased oxidation of Mephenytoin]; [CYP2C19 protein results in increased hydroxylation of Mephenytoin] which results in increased chemical synthesis of 4-hydroxymephenytoin; [CYP2C19 protein results in increased metabolism of Mephenytoin] which results in increased chemical synthesis of 4-hydroxymephenytoin; [Mephenytoin results in decreased activity of CYP2C19 protein] which results in decreased degradation of vanoxerine; Fluoxetine inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Fluoxetine inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; GH1 protein inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Lansoprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Mephenytoin inhibits the reaction [CYP2C19 protein results in increased metabolism of 4,5-dihydropyrazole-1,5-dicarboxylic acid 1-((4-chlorophenyl)-amide) 5-(2-oxo-2H-(1,3')bipyridinyl-6'-yl)-amide]; methyl 2-(2-acetoxy-6,7-dihydrothieno(3,2-c)pyridin-5(4H)-yl)-2-(2-chlorophenyl)acetate inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin analog]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Omeprazole inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Pantoprazole inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; perfluorooctane sulfonic acid inhibits the reaction [CYP2C19 protein results in increased oxidation of Mephenytoin]; rabeprazole-thioether inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Resveratrol inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; sitaxsentan inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Ticlopidine inhibits the reaction [CYP2C19 protein results in increased hydroxylation of Mephenytoin]; Ticlopidine inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Tranylcypromine inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; Ursolic Acid inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]; zafirlukast inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin]
Mephenytoin results in decreased activity of CYP2C29 protein
CYP2C19 gene SNP affects the hydroxylation of Mephenytoin; CYP2C19 protein affects the hydroxylation of Mephenytoin
CYP2C19 protein affects the metabolism of Mephenytoin
CYP2C19 protein results in increased hydroxylation of Mephenytoin; CYP2C19 protein results in increased hydroxylation of Mephenytoin analog 		CTD PMID:3577206 PMID:9170147 PMID:11502731 PMID:11907490 PMID:12401345 More... NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Mephenytoin results in decreased activity of CYP2E1 protein CTD PMID:18420780 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO GH1 protein inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin] CTD PMID:11907490 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Mephenytoin binds to and results in increased activity of NR1I2 protein CTD PMID:15039302 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
nilutamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 increases expression ISO nilutamide results in increased expression of AKT1 protein CTD PMID:16616092 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Ar androgen receptor affects binding
increases response to substance
decreases activity
multiple interactions 		ISO nilutamide binds to AR protein
AR protein mutant form results in increased susceptibility to nilutamide
nilutamide results in decreased activity of AR protein
[AR protein mutant form results in increased susceptibility to nilutamide] which results in increased activity of AR protein mutant form; nilutamide analog binds to and affects the localization of AR protein; nilutamide binds to and results in decreased activity of AR protein; nilutamide inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; nilutamide inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; nilutamide inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA]; nilutamide inhibits the reaction [Metribolone results in increased activity of AR protein]; nilutamide inhibits the reaction [mibolerone affects the localization of AR protein] 		CTD PMID:15509168 PMID:16125883 PMID:16857237 PMID:18324785 PMID:18973785 More... NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO nilutamide results in decreased expression of CDKN1B protein CTD PMID:16616092 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO nilutamide results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO nilutamide binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions EXP nilutamide inhibits the reaction [Dihydrotestosterone results in decreased activity of GAPDH protein] CTD PMID:10650946 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 multiple interactions ISO nilutamide inhibits the reaction [Testosterone results in increased expression of GREB1 mRNA] CTD PMID:16496412 NCBI chr 6:39,440,522...39,562,364
Ensembl chr 6:39,440,504...39,581,633 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions EXP nilutamide inhibits the reaction [Dihydrotestosterone results in decreased expression of IGF1R protein] CTD PMID:10650946 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO nilutamide binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO nilutamide binds to and results in increased activity of PPARG protein CTD PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO nilutamide binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
nitrofurantoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity 		ISO Nitrofurantoin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Nitrofurantoin results in decreased activity of ABCB11 protein 		CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Nitrofurantoin results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects transport
affects abundance
multiple interactions
increases secretion
increases transport
affects response to substance
increases export 		ISO
EXP 		ABCG2 protein affects the transport of Nitrofurantoin
ABCG2 protein affects the abundance of Nitrofurantoin
chrysin inhibits the reaction [ABCG2 protein affects the transport of Nitrofurantoin]; Elacridar inhibits the reaction [ABCG2 protein affects the transport of Nitrofurantoin]
ABCG2 protein results in increased secretion of Nitrofurantoin
ABCG2 protein results in increased transport of Nitrofurantoin
ABCG2 results in increased secretion of Nitrofurantoin
chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]
ABCG2 affects the susceptibility to Nitrofurantoin
chrysin inhibits the reaction [ABCG2 protein results in increased transport of Nitrofurantoin]; Nitrofurantoin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]
ABCG2 protein results in increased export of Nitrofurantoin 		CTD PMID:15709111 PMID:15722455 PMID:17093006 PMID:17785426 PMID:18799806 More... NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Agt angiotensinogen decreases activity EXP Nitrofurantoin results in decreased activity of AGT protein CTD PMID:1313237 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Nitrofurantoin results in increased expression of ALDOA mRNA; Nitrofurantoin results in increased expression of ALDOA protein CTD PMID:11841787 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Cat catalase decreases activity ISO
EXP 		Nitrofurantoin results in decreased activity of CAT protein CTD PMID:1313237 PMID:9000262 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions ISO Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]; Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Rotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]]; Rotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]] CTD PMID:15748169 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP 		Nitrofurantoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Nitrofurantoin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein] CTD PMID:18493746 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression 		ISO NFE2L2 protein affects the reaction [Nitrofurantoin results in increased expression of GCLC protein]; POR protein affects the reaction [Nitrofurantoin results in increased expression of GCLC protein] CTD PMID:34021431 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions 		EXP
ISO 		Nitrofurantoin results in decreased activity of GSR protein
[Nitrofurantoin co-treated with GSR protein] affects the metabolism of Glucose 		CTD PMID:1313237 PMID:1901343 PMID:9000262 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases activity EXP Nitrofurantoin results in increased activity of HIF1A protein CTD PMID:11841787 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Nitrofurantoin results in increased expression of HMOX1 mRNA CTD PMID:7626009 PMID:11841787 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Nitrofurantoin results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 increases expression EXP Nitrofurantoin results in increased expression of HSPA8 mRNA CTD PMID:7626009 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Nitrofurantoin results in increased expression of JUN mRNA CTD PMID:7626009 PMID:11841787 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Nitrofurantoin results in increased expression of LMCD1 mRNA CTD PMID:23558518 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO NFE2L2 protein affects the reaction [Nitrofurantoin results in increased expression of GCLC protein]; Nitrofurantoin results in increased expression of and affects the localization of NFE2L2 protein; POR protein affects the reaction [Nitrofurantoin results in increased expression of NFE2L2 protein] CTD PMID:34021431 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases response to substance
affects reduction 		ISO NQO1 protein results in increased susceptibility to Nitrofurantoin
NQO1 protein affects the reduction of Nitrofurantoin 		CTD PMID:9310146 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Orm1 orosomucoid 1 increases expression EXP Nitrofurantoin results in increased expression of ORM1 mRNA; Nitrofurantoin results in increased expression of ORM1 protein CTD PMID:11841787 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Por cytochrome p450 oxidoreductase increases metabolic processing
multiple interactions
affects metabolic processing 		ISO
EXP 		POR protein results in increased metabolism of Nitrofurantoin
POR protein affects the reaction [Nitrofurantoin results in increased expression of GCLC protein]; POR protein affects the reaction [Nitrofurantoin results in increased expression of NFE2L2 protein]
diphenyleneiodonium inhibits the reaction [POR protein affects the metabolism of Nitrofurantoin]; NADP affects the reaction [POR protein affects the metabolism of Nitrofurantoin]; Nitrofurantoin inhibits the reaction [POR protein results in increased metabolism of Misonidazole] 		CTD PMID:6802140 PMID:18206659 PMID:34021431 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]; Rotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT1 protein]] CTD PMID:15748169 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases activity
increases expression 		ISO
EXP 		Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]; Rotenone promotes the reaction [Nitrofurantoin inhibits the reaction [CNTF protein results in increased phosphorylation of and results in increased activity of STAT3 protein]]
Nitrofurantoin results in increased activity of STAT3 protein
Nitrofurantoin results in increased expression of STAT3 mRNA 		CTD PMID:11841787 PMID:15748169 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Nitrofurantoin results in increased expression of TGFB2 mRNA CTD PMID:23558518 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
oxyphenbutazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Oxyphenbutazone inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Oxyphenbutazone results in increased activity of HSF1 protein CTD PMID:34170685 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
phenylbutazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcat1 branched chain amino acid transaminase 1 increases expression EXP Phenylbutazone results in increased expression of BCAT1 mRNA CTD PMID:23558518 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Phenylbutazone inhibits the reaction [TNF protein results in increased expression of CCND1 protein] CTD PMID:15489888 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Phenylbutazone inhibits the reaction [TNF protein results in increased activity of CHUK protein] CTD PMID:15489888 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
increases activity
multiple interactions 		ISO Phenylbutazone results in increased expression of CYP3A4 mRNA
Phenylbutazone results in increased activity of CYP3A4 protein
NR3C1 protein promotes the reaction [Phenylbutazone results in increased expression of CYP3A4 mRNA] 		CTD PMID:9512926 PMID:10219967 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Phenylbutazone inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression EXP Phenylbutazone results in increased expression of HAVCR1 mRNA CTD PMID:23142791 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Krt14 keratin 14 increases expression EXP Phenylbutazone results in increased expression of KRT14 mRNA CTD PMID:23142791 NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 increases expression EXP Phenylbutazone results in increased expression of LMCD1 mRNA CTD PMID:23558518 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Phenylbutazone inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Phenylbutazone inhibits the reaction [TNF protein results in increased activity of NFKB1 protein] CTD PMID:15489888 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Phenylbutazone inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein] CTD PMID:15489888 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO NR3C1 protein promotes the reaction [Phenylbutazone results in increased expression of CYP3A4 mRNA] CTD PMID:10219967 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Phenylbutazone inhibits the reaction [TNF protein results in increased expression of PTGS2 protein] CTD PMID:15489888 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Phenylbutazone inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Phenylbutazone inhibits the reaction [TNF protein results in increased activity of RELA protein] CTD PMID:15489888 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rnd1 Rho family GTPase 1 increases expression EXP Phenylbutazone results in increased expression of RND1 mRNA CTD PMID:23558518 NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399 		JBrowse link
G Sell selectin L affects expression ISO Phenylbutazone affects the expression of SELL protein CTD PMID:12147693 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Phenylbutazone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid] CTD PMID:21272127 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases expression EXP Phenylbutazone results in increased expression of TGFB2 mRNA CTD PMID:23558518 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Phenylbutazone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Phenylbutazone inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Phenylbutazone inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Phenylbutazone inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Phenylbutazone inhibits the reaction [TNF protein results in increased activity of RELA protein]; Phenylbutazone inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Phenylbutazone inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Phenylbutazone inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]
[Phenylbutazone co-treated with Lipopolysaccharides] results in increased secretion of TNF protein 		CTD PMID:10328874 PMID:15489888 PMID:17328244 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO Phenylbutazone inhibits the reaction [UGT1A1 protein results in increased glucuronidation of Diethylstilbestrol] CTD PMID:23126256 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions ISO Phenylbutazone inhibits the reaction [UGT1A3 protein results in increased glucuronidation of Diethylstilbestrol] CTD PMID:23126256 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
phenytoin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin decreases expression EXP Phenytoin results in decreased expression of AAAS mRNA CTD PMID:20345932 NCBI chr 7:133,464,315...133,483,961
Ensembl chr 7:133,464,315...133,483,961 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Phenytoin results in decreased expression of ABCA1 mRNA CTD PMID:15136057 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance
multiple interactions
increases expression
increases transport
decreases activity
increases metabolic processing
affects abundance 		ISO
EXP 		ABCB1 protein affects the susceptibility to Phenytoin
Amino Acids, Peptides, and Proteins inhibits the reaction [Phenytoin results in increased expression of ABCB1 protein]; Phenytoin results in increased expression of and results in increased activity of ABCB1A protein
ABCB1A protein results in increased transport of Phenytoin
Phenytoin results in decreased activity of ABCB1 protein
ABCB1 protein results in increased metabolism of Phenytoin
ABCB1 protein affects the abundance of Phenytoin 		CTD PMID:8001500 PMID:10580886 PMID:14749549 PMID:15569486 PMID:16220110 More... NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects abundance ISO ABCB1B protein affects the abundance of Phenytoin CTD PMID:12122045 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases expression 		EXP KN 62 inhibits the reaction [Phenytoin results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC1 protein] CTD PMID:18473823 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
affects response to substance
increases expression
multiple interactions 		EXP
ISO 		ABCC2 protein affects the transport of Phenytoin
ABCC2 protein affects the susceptibility to Phenytoin
Phenytoin results in increased expression of ABCC2 protein
KN 62 inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein] 		CTD PMID:12663688 PMID:14636316 PMID:17376120 PMID:18473823 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Phenytoin results in increased expression of ABCC3 mRNA CTD PMID:17381134 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Phenytoin results in decreased expression of ABCG1 mRNA CTD PMID:15136057 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abhd5 abhydrolase domain containing 5, lysophosphatidic acid acyltransferase increases expression EXP Phenytoin results in increased expression of ABHD5 mRNA CTD PMID:20345932 NCBI chr 8:130,877,834...130,903,947
Ensembl chr 8:122,000,389...122,026,447 		JBrowse link
G Ablim1 actin-binding LIM protein 1 decreases expression ISO Phenytoin results in decreased expression of ABLIM1 mRNA CTD PMID:15136057 NCBI chr 1:256,083,747...256,372,075
Ensembl chr 1:256,084,297...256,371,969 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Phenytoin results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ache acetylcholinesterase increases activity ISO Phenytoin results in increased activity of ACHE protein CTD PMID:16946593 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 decreases expression ISO Phenytoin results in decreased expression of ADAM8 mRNA CTD PMID:14741686 NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression EXP Phenytoin results in increased expression of ADAMTS9 mRNA CTD PMID:20345932 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Adgrb3 adhesion G protein-coupled receptor B3 increases expression EXP Phenytoin results in increased expression of ADGRB3 mRNA CTD PMID:20345932 NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855 		JBrowse link
G Adrb3 adrenoceptor beta 3 decreases expression EXP Phenytoin results in decreased expression of ADRB3 mRNA CTD PMID:20345932 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Afp alpha-fetoprotein decreases expression ISO Phenytoin results in decreased expression of AFP mRNA CTD PMID:14741686 PMID:26272751 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 decreases expression EXP Phenytoin results in decreased expression of AGAP3 mRNA CTD PMID:20345932 NCBI chr 4:10,674,746...10,724,848
Ensembl chr 4:10,674,064...10,725,244 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases expression 		ISO
EXP 		CYP3A11 protein affects the reaction [Phenytoin results in increased expression of AHR mRNA]
Phenytoin results in increased expression of AHR protein
Ketoconazole inhibits the reaction [Phenytoin results in increased expression of AHR protein] 		CTD PMID:17505019 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Akap10 A-kinase anchoring protein 10 increases expression EXP Phenytoin results in increased expression of AKAP10 mRNA CTD PMID:20345932 NCBI chr10:46,545,371...46,608,730
Ensembl chr10:46,551,532...46,608,769 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 decreases expression
increases expression 		EXP Phenytoin results in decreased expression of AKR7A3 mRNA
Phenytoin results in increased expression of AKR7A3 mRNA 		CTD PMID:17381134 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Phenytoin results in increased expression of ALDH1A1 mRNA CTD PMID:17381134 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases expression ISO Phenytoin results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP Phenytoin results in increased expression of ALDH1A7 mRNA CTD PMID:15120968 NCBI chr 1:218,201,443...218,241,410
Ensembl chr 1:218,201,472...218,248,906 		JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog increases expression EXP Phenytoin results in increased expression of AMN1 mRNA CTD PMID:20345932 NCBI chr 4:182,155,140...182,182,085
Ensembl chr 4:182,155,142...182,182,016 		JBrowse link
G Anxa4 annexin A4 increases expression ISO Phenytoin results in increased expression of ANXA4 mRNA CTD PMID:14741686 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Anxa5 annexin A5 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA CTD PMID:21224054 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apoa1 apolipoprotein A1 increases expression ISO Phenytoin results in increased expression of APOA1 mRNA CTD PMID:15136057 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa4 apolipoprotein A4 increases expression ISO Phenytoin results in increased expression of APOA4 mRNA CTD PMID:15136057 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoe apolipoprotein E increases expression ISO Phenytoin results in increased expression of APOE mRNA CTD PMID:15136057 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Ar androgen receptor multiple interactions
increases activity
increases expression 		ISO
EXP 		[Phenytoin co-treated with Prednisolone] results in increased expression of AR protein
Phenytoin results in increased activity of AR protein
Phenytoin results in increased expression of AR mRNA; Phenytoin results in increased expression of AR protein
Ketoconazole inhibits the reaction [Phenytoin results in increased expression of AR protein] 		CTD PMID:19226368 PMID:19490052 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arfip1 ARF interacting protein 1 increases expression EXP Phenytoin results in increased expression of ARFIP1 mRNA CTD PMID:20345932 NCBI chr 2:169,843,804...169,924,136
Ensembl chr 2:169,843,801...169,923,142 		JBrowse link
G Arhgap39 Rho GTPase activating protein 39 increases expression EXP Phenytoin results in increased expression of ARHGAP39 mRNA CTD PMID:20345932 NCBI chr 7:108,446,280...108,538,875
Ensembl chr 7:108,446,282...108,538,831 		JBrowse link
G Armc8 armadillo repeat containing 8 increases expression EXP Phenytoin results in increased expression of ARMC8 mRNA CTD PMID:20345932 NCBI chr 8:100,036,946...100,131,544
Ensembl chr 8:100,036,946...100,131,520 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein CTD PMID:21224054 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atpaf1 ATP synthase mitochondrial F1 complex assembly factor 1 decreases expression EXP Phenytoin results in decreased expression of ATPAF1 mRNA CTD PMID:20345932 NCBI chr 5:129,265,789...129,292,463
Ensembl chr 5:129,266,404...129,293,556 		JBrowse link
G B4galt7 beta-1,4-galactosyltransferase 7 decreases expression EXP Phenytoin results in decreased expression of B4GALT7 mRNA CTD PMID:20345932 NCBI chr17:9,018,514...9,027,591
Ensembl chr17:9,018,935...9,027,573 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA CTD PMID:21224054 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression 		ISO Phenytoin results in increased expression of and affects the localization of BCL2 protein
Phenytoin results in decreased expression of BCL2 mRNA 		CTD PMID:9118846 PMID:10695937 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA CTD PMID:21224054 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bmp1 bone morphogenetic protein 1 decreases expression ISO Phenytoin results in decreased expression of BMP1 mRNA CTD PMID:14741686 NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776 		JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO Phenytoin results in increased expression of BMP4 mRNA CTD PMID:16141649 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G C2 complement C2 decreases expression EXP Phenytoin results in decreased expression of C2 mRNA CTD PMID:20345932 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cacybp calcyclin binding protein increases expression EXP Phenytoin results in increased expression of CACYBP mRNA CTD PMID:20345932 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177 		JBrowse link
G Calca calcitonin-related polypeptide alpha decreases expression EXP Phenytoin results in decreased expression of CALCA protein CTD PMID:2470235 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Phenytoin results in decreased expression of CALM2 mRNA CTD PMID:14741686 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Capn5 calpain 5 decreases expression ISO Phenytoin results in decreased expression of CAPN5 mRNA CTD PMID:14741686 NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923 		JBrowse link
G Car6 carbonic anhydrase 6 increases expression EXP Phenytoin results in increased expression of CAR6 mRNA CTD PMID:20345932 NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644 		JBrowse link
G Caskin1 CASK interacting protein 1 affects expression EXP Phenytoin affects the expression of CASKIN1 mRNA CTD PMID:20345932 NCBI chr10:13,512,684...13,533,380
Ensembl chr10:13,513,465...13,533,377 		JBrowse link
G Cat catalase decreases response to substance ISO CAT protein results in decreased susceptibility to Phenytoin CTD PMID:21252394 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbll1 Cbl proto-oncogene like 1 increases expression EXP Phenytoin results in increased expression of CBLL1 mRNA CTD PMID:20345932 NCBI chr 6:53,798,712...53,812,890
Ensembl chr 6:48,071,190...48,086,444 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Phenytoin results in increased expression of CCL2 protein CTD PMID:14578793 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnc cyclin C increases expression EXP Phenytoin results in increased expression of CCNC mRNA CTD PMID:20345932 NCBI chr 5:40,063,589...40,081,731
Ensembl chr 5:35,266,823...35,296,584 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression 		ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA
MIR4680 affects the reaction [Phenytoin results in decreased expression of CCND1 protein]
Phenytoin results in decreased expression of CCND1 mRNA; Phenytoin results in decreased expression of CCND1 protein 		CTD PMID:14741686 PMID:21224054 PMID:38191190 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 decreases expression
multiple interactions 		ISO Phenytoin results in decreased expression of CCNE1 protein
MIR4680 affects the reaction [Phenytoin results in decreased expression of CCNE1 protein] 		CTD PMID:38191190 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA CTD PMID:21224054 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd47 Cd47 molecule decreases expression EXP Phenytoin results in decreased expression of CD47 mRNA CTD PMID:17381134 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cdh2 cadherin 2 decreases expression ISO Phenytoin results in decreased expression of CDH2 mRNA CTD PMID:9118846 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Phenytoin results in decreased expression of CDK1 mRNA CTD PMID:26272751 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions 		ISO Phenytoin results in decreased expression of CDKN1A mRNA
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein 		CTD PMID:14741686 PMID:21224054 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdx2 caudal type homeo box 2 increases expression EXP Phenytoin results in increased expression of CDX2 mRNA CTD PMID:20345932 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142 		JBrowse link
G Cela2a chymotrypsin like elastase 2A decreases expression ISO Phenytoin results in decreased expression of CELA2A mRNA CTD PMID:14741686 NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632 		JBrowse link
G Cep57 centrosomal protein 57 increases expression EXP Phenytoin results in increased expression of CEP57 mRNA CTD PMID:20345932 NCBI chr 8:10,669,588...10,689,257
Ensembl chr 8:10,669,590...10,689,249 		JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist decreases expression ISO Phenytoin results in decreased expression of CER1 mRNA CTD PMID:26272751 NCBI chr 5:97,306,427...97,309,783
Ensembl chr 5:97,306,431...97,309,783 		JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA CTD PMID:21224054 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Ckm creatine kinase, M-type increases expression ISO Phenytoin results in increased expression of CKM protein CTD PMID:6682525 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720 		JBrowse link
G Clcn6 chloride voltage-gated channel 6 decreases expression EXP Phenytoin results in decreased expression of CLCN6 mRNA CTD PMID:20345932 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 increases expression EXP Phenytoin results in increased expression of CMPK1 mRNA CTD PMID:20345932 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 increases expression EXP Phenytoin results in increased expression of CNOT7 mRNA CTD PMID:20345932 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression ISO Phenytoin results in increased expression of COL11A1 mRNA CTD PMID:14741686 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain decreases expression ISO Phenytoin results in decreased expression of COL18A1 mRNA CTD PMID:14741686 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
decreases expression 		ISO Phenytoin inhibits the reaction [IL1B protein results in decreased expression of COL1A1 mRNA]
Phenytoin results in increased expression of COL1A1 mRNA
Phenytoin results in decreased expression of COL1A1 mRNA 		CTD PMID:8971655 PMID:14741686 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
affects expression 		ISO Phenytoin results in increased expression of COL1A2 mRNA
Phenytoin affects the expression of COL1A2 mRNA 		CTD PMID:14741686 PMID:24704097 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain decreases expression
increases expression 		ISO Phenytoin results in decreased expression of COL6A1 mRNA
Phenytoin results in increased expression of COL6A1 mRNA 		CTD PMID:8224229 PMID:14741686 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression ISO Phenytoin results in increased expression of COL6A2 mRNA CTD PMID:8224229 NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression ISO Phenytoin results in increased expression of COL6A3 mRNA CTD PMID:8224229 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Cp ceruloplasmin decreases expression EXP Phenytoin results in decreased expression of CP mRNA CTD PMID:17381134 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 increases expression EXP Phenytoin results in increased expression of CPSF6 mRNA CTD PMID:20345932 NCBI chr 7:52,956,589...53,001,783
Ensembl chr 7:52,956,589...52,988,122 		JBrowse link
G Crh corticotropin releasing hormone affects expression EXP Phenytoin affects the expression of CRH mRNA CTD PMID:20345932 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crppa CDP-L-ribitol pyrophosphorylase A increases expression EXP Phenytoin results in increased expression of CRPPA mRNA CTD PMID:20345932 NCBI chr 6:53,120,264...53,397,030
Ensembl chr 6:53,121,438...53,397,028 		JBrowse link
G Ctsb cathepsin B increases expression
decreases activity 		ISO Phenytoin results in increased expression of CTSB mRNA
Phenytoin results in decreased activity of CTSB protein 		CTD PMID:10914799 PMID:14741686 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsl cathepsin L increases expression
decreases activity 		ISO Phenytoin results in increased expression of CTSL mRNA
Phenytoin results in decreased activity of CTSL protein 		CTD PMID:10914799 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cul4a cullin 4A increases expression EXP Phenytoin results in increased expression of CUL4A mRNA CTD PMID:20345932 NCBI chr16:83,086,688...83,124,503
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Phenytoin results in increased expression of CX3CL1 mRNA CTD PMID:20345932 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA CTD PMID:21224054 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of CXCL2 mRNA; Alprostadil inhibits the reaction [[Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of CXCL2 mRNA] CTD PMID:23986454 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity ISO Phenytoin results in decreased activity of CYP19A1 protein CTD PMID:17959350 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression EXP
ISO 		Phenytoin results in increased expression of CYP1A1 mRNA CTD PMID:9860486 PMID:17381134 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Phenytoin CTD PMID:23397584 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA CTD PMID:21224054 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression
increases expression 		EXP Phenytoin results in decreased expression of CYP2B1 mRNA
Phenytoin results in increased expression of CYP2B1 mRNA 		CTD PMID:9819145 PMID:10945841 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Phenytoin results in increased expression of CYP2B2 mRNA CTD PMID:10945841 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases expression
increases expression
increases activity 		ISO [Phenytoin results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]]]; N-(3-(aminomethyl)benzyl)acetamidine inhibits the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]; NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP2B6 protein]; NR1I2 protein affects the reaction [Phenytoin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]; NR1I3 protein affects the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]; Phenytoin results in increased expression of and results in increased activity of CYP2B6 protein; pimagedine inhibits the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]
Phenytoin results in decreased expression of CYP2B10 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA
Phenytoin results in increased expression of CYP2B6 mRNA; Phenytoin results in increased expression of CYP2B6 protein
Phenytoin results in increased activity of CYP2B6 protein 		CTD PMID:12571232 PMID:12695351 PMID:14977870 PMID:15123723 PMID:17041008 More... NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
increases expression
affects expression
affects metabolic processing
increases metabolic processing
decreases metabolic processing
increases hydroxylation
decreases hydroxylation 		ISO
EXP 		[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Phenytoin
[Phenytoin results in decreased activity of CYP2C29 protein] which results in decreased reduction of and results in decreased oxidation of 9-anthraldehyde; NR1I3 protein affects the reaction [Phenytoin results in increased expression of CYP2C29 mRNA]
Phenytoin results in increased expression of CYP2C protein; Phenytoin results in increased expression of CYP2C29 mRNA; Phenytoin results in increased expression of CYP2C29 protein
Phenytoin affects the expression of CYP2C29 mRNA
CYP2C19 protein affects the metabolism of Phenytoin
CYP2C19 protein results in increased metabolism of Phenytoin
CYP2C19 gene polymorphism results in decreased metabolism of Phenytoin
CYP2C19 protein results in increased hydroxylation of Phenytoin
CYP2C19 gene polymorphism results in decreased hydroxylation of Phenytoin 		CTD PMID:9146858 PMID:9333104 PMID:9579299 PMID:9860067 PMID:12051692 More... NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 increases metabolic processing EXP CYP2C9 protein results in increased metabolism of Phenytoin CTD PMID:15569425 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Phenytoin CTD PMID:23397584 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases expression
increases expression 		ISO
EXP 		NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP2E1 mRNA]
Phenytoin results in decreased expression of CYP2E1 mRNA
Phenytoin results in increased expression of CYP2E1 mRNA; Phenytoin results in increased expression of CYP2E1 protein 		CTD PMID:17381134 PMID:18206661 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions
increases activity 		EXP
ISO 		Phenytoin results in increased expression of CYP3A2 mRNA; Phenytoin results in increased expression of CYP3A2 protein
[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Phenytoin; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Phenytoin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; NOC 18 inhibits the reaction [Phenytoin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Phenytoin results in increased expression of CYP3A4 mRNA]; NR3C1 protein promotes the reaction [Phenytoin results in increased expression of CYP3A4 mRNA]; Phenytoin promotes the reaction [CYP3A4 protein results in increased hydroxylation of Cholecalciferol]; Phenytoin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]
Phenytoin results in increased activity of CYP3A4 protein
Phenytoin results in increased expression of CYP3A4 mRNA; Phenytoin results in increased expression of CYP3A4 protein
Ketoconazole inhibits the reaction [Phenytoin results in increased expression of CYP3A2 protein] 		CTD PMID:9512926 PMID:10219967 PMID:12065438 PMID:12505310 PMID:12673034 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 decreases expression
increases expression 		EXP Phenytoin results in decreased expression of CYP3A23-3A1 mRNA
Phenytoin results in increased expression of CYP3A23-3A1 mRNA 		CTD PMID:10945841 PMID:17381134 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO Phenytoin results in increased expression of CYP3A5 mRNA
Phenytoin results in increased expression of CYP3A13 mRNA 		CTD PMID:12673034 PMID:19903449 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression EXP Phenytoin results in decreased expression of CYP4A1 mRNA CTD PMID:17381134 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA CTD PMID:21224054 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 increases expression EXP Phenytoin results in increased expression of CYP7B1 mRNA CTD PMID:20345932 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Dap3 death associated protein 3 increases expression ISO Phenytoin results in increased expression of DAP3 mRNA CTD PMID:14741686 NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461 		JBrowse link
G Dapk2 death-associated protein kinase 2 decreases expression ISO Phenytoin results in decreased expression of DAPK2 mRNA CTD PMID:14741686 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA CTD PMID:21224054 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dhx9 DExH-box helicase 9 increases expression EXP Phenytoin results in increased expression of DHX9 mRNA CTD PMID:20345932 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Dmtn dematin actin binding protein decreases expression EXP Phenytoin results in decreased expression of DMTN mRNA CTD PMID:20345932 NCBI chr15:45,677,974...45,702,261
Ensembl chr15:45,677,977...45,705,601 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA CTD PMID:21224054 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA CTD PMID:21224054 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Ebpl EBP like increases expression EXP Phenytoin results in increased expression of EBPL mRNA CTD PMID:20345932 NCBI chr15:35,508,074...35,531,472
Ensembl chr15:35,508,074...35,531,472 		JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA CTD PMID:21224054 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr3 early growth response 3 increases expression EXP Phenytoin results in increased expression of EGR3 mRNA CTD PMID:20345932 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression EXP Phenytoin results in increased expression of EIF1A mRNA CTD PMID:20345932 NCBI chr18:39,325,695...39,338,043
Ensembl chr18:39,325,202...39,338,696 		JBrowse link
G Emx2 empty spiracles homeobox 2 decreases expression ISO Phenytoin results in decreased expression of EMX2 mRNA CTD PMID:9118846 NCBI chr 1:258,626,584...258,633,594
Ensembl chr 1:258,626,584...258,633,594 		JBrowse link
G Enpep glutamyl aminopeptidase decreases expression
increases expression 		EXP Phenytoin results in decreased expression of ENPEP mRNA
Phenytoin results in increased expression of ENPEP mRNA 		CTD PMID:17381134 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
G Eomes eomesodermin increases expression ISO Phenytoin results in increased expression of EOMES mRNA CTD PMID:14741686 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Ephx1 epoxide hydrolase 1 affects response to substance
increases expression 		ISO
EXP 		EPHX1 gene polymorphism affects the susceptibility to Phenytoin
Phenytoin results in increased expression of EPHX1 mRNA 		CTD PMID:17381134 PMID:19952982 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Ephx2 epoxide hydrolase 2 decreases expression EXP Phenytoin results in decreased expression of EPHX2 mRNA CTD PMID:17381134 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression
multiple interactions 		ISO Phenytoin results in decreased expression of ERBB2 mRNA; Phenytoin results in decreased expression of ERBB2 protein
MIR4680 affects the reaction [Phenytoin results in decreased expression of ERBB2 mRNA]; MIR4680 affects the reaction [Phenytoin results in decreased expression of ERBB2 protein] 		CTD PMID:38191190 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Phenytoin results in increased expression of ESR1 mRNA; Phenytoin results in increased expression of ESR1 protein CTD PMID:19490052 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Phenytoin results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G F10 coagulation factor X decreases expression EXP Phenytoin results in decreased expression of F10 mRNA CTD PMID:17381134 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO [clobazam co-treated with Phenytoin] results in increased expression of [F2 protein binds to SERPINC1 protein] CTD PMID:16376047 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Faslg Fas ligand multiple interactions
decreases expression 		ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA; [Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of FASL mRNA
Phenytoin results in decreased expression of FASL mRNA 		CTD PMID:21224054 PMID:23986454 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fbxl3 F-box and leucine-rich repeat protein 3 increases expression EXP Phenytoin results in increased expression of FBXL3 mRNA CTD PMID:20345932 NCBI chr15:86,321,504...86,341,387
Ensembl chr15:79,906,795...79,927,867 		JBrowse link
G Fbxo30 F-box protein 30 increases expression EXP Phenytoin results in increased expression of FBXO30 mRNA CTD PMID:20345932 NCBI chr 1:7,475,636...7,491,719
Ensembl chr 1:5,655,339...5,672,441 		JBrowse link
G Fgf12 fibroblast growth factor 12 increases expression EXP Phenytoin results in increased expression of FGF12 mRNA CTD PMID:20345932 NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607 		JBrowse link
G Fgf5 fibroblast growth factor 5 increases expression ISO Phenytoin results in increased expression of FGF5 mRNA CTD PMID:14741686 NCBI chr14:11,323,827...11,346,164
Ensembl chr14:11,325,334...11,345,997 		JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO Phenytoin results in increased expression of FGF8 mRNA CTD PMID:31711903 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Fgf9 fibroblast growth factor 9 increases expression ISO Phenytoin results in increased expression of FGF9 mRNA CTD PMID:14741686 NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 increases expression ISO Phenytoin results in increased expression of FGFR2 mRNA; Phenytoin results in increased expression of FGFR2 protein CTD PMID:11352631 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Flrt2 fibronectin leucine rich transmembrane protein 2 increases expression ISO Phenytoin results in increased expression of FLRT2 mRNA CTD PMID:14741686 NCBI chr 6:114,777,547...114,872,688
Ensembl chr 6:114,777,599...114,872,785 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA CTD PMID:21224054 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA CTD PMID:21224054 NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Fmod fibromodulin decreases expression ISO Phenytoin results in decreased expression of FMOD mRNA CTD PMID:14741686 NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 increases expression EXP Phenytoin results in increased expression of FMR1 mRNA CTD PMID:20345932 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fn1 fibronectin 1 increases expression ISO Phenytoin results in increased expression of FN1 mRNA CTD PMID:14741686 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fndc3a fibronectin type III domain containing 3a increases expression EXP Phenytoin results in increased expression of FNDC3A mRNA CTD PMID:20345932 NCBI chr15:47,689,909...47,867,354
Ensembl chr15:47,689,919...47,866,784 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression 		EXP [Phenytoin co-treated with Drugs, Chinese Herbal] inhibits the reaction [Kainic Acid results in increased expression of FOS mRNA]
Phenytoin results in decreased expression of FOS protein 		CTD PMID:7789465 PMID:8758711 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO Phenytoin results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Foxp3 forkhead box P3 multiple interactions
decreases expression 		ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of FOXP3 mRNA
Phenytoin results in decreased expression of FOXP3 mRNA 		CTD PMID:23986454 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 decreases expression ISO Phenytoin results in decreased expression of FRS3 mRNA CTD PMID:14741686 NCBI chr 9:13,288,559...13,297,285
Ensembl chr 9:13,288,667...13,295,382 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP Phenytoin results in decreased expression of G6PC1 mRNA CTD PMID:17381134 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase affects response to substance ISO G6PDX protein affects the susceptibility to Phenytoin CTD PMID:10627286 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA CTD PMID:21224054 NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gata3 GATA binding protein 3 multiple interactions
decreases expression 		ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of GATA3 mRNA
Phenytoin results in decreased expression of GATA3 mRNA 		CTD PMID:23986454 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression EXP Phenytoin results in increased expression of GCLM mRNA CTD PMID:20345932 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Glul glutamate-ammonia ligase decreases activity ISO Phenytoin results in decreased activity of GLUL protein CTD PMID:10323596 NCBI chr13:68,519,500...68,585,554
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gnl2 G protein nucleolar 2 increases expression EXP Phenytoin results in increased expression of GNL2 mRNA CTD PMID:20345932 NCBI chr 5:137,293,141...137,318,528
Ensembl chr 5:137,293,081...137,318,526 		JBrowse link
G Gnpda2 glucosamine-6-phosphate deaminase 2 increases expression EXP Phenytoin results in increased expression of GNPDA2 mRNA CTD PMID:20345932 NCBI chr14:38,520,663...38,538,713
Ensembl chr14:38,520,705...38,538,713 		JBrowse link
G Gpm6a glycoprotein m6a increases expression EXP Phenytoin results in increased expression of GPM6A mRNA CTD PMID:20345932 NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475 		JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA CTD PMID:21224054 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 increases expression EXP Phenytoin results in increased expression of GRIN1 mRNA CTD PMID:20345932 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression ISO Phenytoin results in increased expression of GSTA1 mRNA CTD PMID:11134551 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
decreases expression 		EXP Phenytoin results in increased expression of GSTA2 mRNA
Phenytoin results in decreased expression of GSTA2 mRNA 		CTD PMID:17381134 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO Phenytoin results in decreased expression of GSTK1 mRNA CTD PMID:14741686 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
multiple interactions 		EXP
ISO 		Phenytoin results in increased expression of GSTM1 mRNA
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein 		CTD PMID:17381134 PMID:21224054 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP Phenytoin results in increased expression of GSTM2 mRNA CTD PMID:17381134 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA CTD PMID:21224054 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases expression ISO Phenytoin results in decreased expression of GSTO1 mRNA CTD PMID:14741686 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468 		JBrowse link
G Gusb glucuronidase, beta multiple interactions
decreases activity 		ISO Phenytoin inhibits the reaction [Misonidazole results in increased activity of GUSB protein]
Phenytoin results in decreased activity of GUSB protein 		CTD PMID:6696821 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905 		JBrowse link
G Hdac7 histone deacetylase 7 increases expression ISO Phenytoin results in increased expression of HDAC7 mRNA CTD PMID:26272751 NCBI chr 7:128,923,918...128,961,926
Ensembl chr 7:128,923,920...128,962,072 		JBrowse link
G Helz helicase with zinc finger increases expression EXP Phenytoin results in increased expression of HELZ mRNA CTD PMID:20345932 NCBI chr10:92,479,403...92,645,234
Ensembl chr10:92,501,518...92,638,383 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression EXP Phenytoin results in increased expression of HEXIM1 mRNA CTD PMID:20345932 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in increased secretion of HMGB1 protein CTD PMID:23986454 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression 		ISO
EXP 		[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA
Phenytoin results in increased expression of HMOX1 mRNA 		CTD PMID:17381134 PMID:21224054 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression EXP Phenytoin results in increased expression of HNRNPA2B1 mRNA CTD PMID:20345932 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hook3 hook microtubule-tethering protein 3 increases expression EXP Phenytoin results in increased expression of HOOK3 mRNA CTD PMID:20345932 NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338 		JBrowse link
G Hoxa2 homeobox A2 decreases expression ISO Phenytoin results in decreased expression of HOXA2 mRNA; Phenytoin results in decreased expression of HOXA2 protein CTD PMID:10789828 NCBI chr 4:81,262,668...81,266,970
Ensembl chr 4:81,262,768...81,265,044 		JBrowse link
G Hoxb7 homeo box B7 increases expression ISO Phenytoin results in increased expression of HOXB7 mRNA CTD PMID:31711903 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034 		JBrowse link
G Hoxb9 homeo box B9 increases expression ISO Phenytoin results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA CTD PMID:21224054 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA CTD PMID:21224054 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA CTD PMID:21224054 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA CTD PMID:21224054 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA CTD PMID:21224054 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Ifng interferon gamma decreases expression ISO Phenytoin results in decreased expression of IFNG protein CTD PMID:10982153 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Phenytoin results in increased expression of IFNGR1 mRNA CTD PMID:14741686 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Ifngr2 interferon gamma receptor 2 increases expression ISO Phenytoin results in increased expression of IFNGR2 mRNA CTD PMID:14741686 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP Phenytoin results in decreased expression of IGF1 mRNA CTD PMID:17381134 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 increases expression ISO Phenytoin results in increased expression of IGF2 mRNA CTD PMID:9988880 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO Phenytoin results in increased expression of IHH mRNA CTD PMID:16141649 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in increased secretion of IL17A protein CTD PMID:23986454 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Phenytoin inhibits the reaction [IL1B protein results in decreased expression of COL1A1 mRNA]
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of IL1B mRNA; [Phenytoin co-treated with Buthionine Sulfoximine] results in increased secretion of IL1B protein 		CTD PMID:8971655 PMID:21224054 PMID:23986454 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of IL23A mRNA CTD PMID:23986454 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression 		ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA; [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of IL6 mRNA
Phenytoin results in increased expression of IL6 mRNA 		CTD PMID:21224054 PMID:23986454 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Phenytoin results in decreased expression of IL6RA mRNA CTD PMID:15136057 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F increases expression EXP Phenytoin results in increased expression of INPP5F mRNA CTD PMID:20345932 NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276 		JBrowse link
G Insr insulin receptor increases expression ISO Phenytoin results in increased expression of INSR mRNA CTD PMID:14741686 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883 		JBrowse link
G Ipp intracisternal A particle-promoted polypeptide increases expression EXP Phenytoin results in increased expression of IPP mRNA CTD PMID:20345932 NCBI chr 5:129,962,528...130,001,237
Ensembl chr 5:129,962,643...130,001,242 		JBrowse link
G Irf9 interferon regulatory factor 9 increases expression EXP Phenytoin results in increased expression of IRF9 mRNA CTD PMID:20345932 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236 		JBrowse link
G Itga2 integrin subunit alpha 2 decreases expression ISO Phenytoin results in decreased expression of ITGA2 protein CTD PMID:15948689 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itga8 integrin subunit alpha 8 increases expression ISO Phenytoin results in increased expression of ITGA8 mRNA CTD PMID:14741686 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510 		JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Phenytoin results in decreased expression of ITGB1 protein CTD PMID:15948689 NCBI chr19:73,602,277...73,650,271
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein increases expression EXP Phenytoin results in increased expression of ITGB3BP mRNA CTD PMID:20345932 NCBI chr 5:119,575,657...119,640,974
Ensembl chr 5:114,460,221...114,525,704 		JBrowse link
G Jade1 jade family PHD finger 1 multiple interactions
decreases expression 		ISO MIR4680 affects the reaction [Phenytoin results in decreased expression of JADE1 mRNA]; MIR4680 affects the reaction [Phenytoin results in decreased expression of JADE1 protein]
Phenytoin results in decreased expression of JADE1 mRNA; Phenytoin results in decreased expression of JADE1 protein 		CTD PMID:38191190 NCBI chr 2:126,471,124...126,524,252
Ensembl chr 2:124,543,286...124,596,354 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Phenytoin results in decreased expression of JUN mRNA CTD PMID:9118846 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 increases expression EXP Phenytoin results in increased expression of KCND2 mRNA CTD PMID:20345932 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Phenytoin results in decreased activity of KCNH2 protein CTD PMID:21158687 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kctd3 potassium channel tetramerization domain containing 3 increases expression EXP Phenytoin results in increased expression of KCTD3 mRNA CTD PMID:20345932 NCBI chr13:100,510,193...100,548,765
Ensembl chr13:100,510,195...100,548,718 		JBrowse link
G Kdr kinase insert domain receptor increases expression ISO Phenytoin results in increased expression of KDR mRNA CTD PMID:26272751 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Khdrbs2 KH RNA binding domain containing, signal transduction associated 2 increases expression EXP Phenytoin results in increased expression of KHDRBS2 mRNA CTD PMID:20345932 NCBI chr 9:34,447,023...34,953,684
Ensembl chr 9:34,447,056...34,915,530 		JBrowse link
G Klf2 KLF transcription factor 2 increases expression EXP Phenytoin results in increased expression of KLF2 mRNA CTD PMID:20345932 NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klhl2 kelch-like family member 2 increases expression EXP Phenytoin results in increased expression of KLHL2 mRNA CTD PMID:20345932 NCBI chr16:29,627,171...29,739,782
Ensembl chr16:24,860,667...24,973,341 		JBrowse link
G Klhl7 kelch-like family member 7 increases expression EXP Phenytoin results in increased expression of KLHL7 mRNA CTD PMID:20345932 NCBI chr 4:11,006,366...11,055,399
Ensembl chr 4:11,006,375...11,055,541 		JBrowse link
G Krit1 KRIT1, ankyrin repeat containing increases expression EXP Phenytoin results in increased expression of KRIT1 mRNA CTD PMID:20345932 NCBI chr 4:30,299,203...30,333,366
Ensembl chr 4:30,299,203...30,333,359 		JBrowse link
G Krt2 keratin 2 increases expression ISO Phenytoin results in increased expression of KRT2 mRNA CTD PMID:14741686 NCBI chr 7:132,940,879...132,948,031
Ensembl chr 7:132,940,862...132,947,963 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 increases activity EXP Phenytoin results in increased activity of KYAT1 protein CTD PMID:16765940 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Lama2 laminin subunit alpha 2 increases expression EXP Phenytoin results in increased expression of LAMA2 mRNA CTD PMID:20345932 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530 		JBrowse link
G Lap3 leucine aminopeptidase 3 affects expression EXP Phenytoin affects the expression of LAP3 mRNA CTD PMID:20345932 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359 		JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression ISO Phenytoin results in increased expression of LCAT mRNA CTD PMID:15136057 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Ldb2 LIM domain binding 2 increases expression EXP Phenytoin results in increased expression of LDB2 mRNA CTD PMID:20345932 NCBI chr14:66,277,044...66,598,071
Ensembl chr14:66,277,085...66,597,778 		JBrowse link
G Lpin1 lipin 1 increases expression ISO Phenytoin results in increased expression of LPIN1 mRNA CTD PMID:14741686 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097 		JBrowse link
G Lrba LPS responsive beige-like anchor protein increases expression EXP Phenytoin results in increased expression of LRBA mRNA CTD PMID:20345932 NCBI chr 2:171,623,668...172,202,576
Ensembl chr 2:171,621,507...172,202,724 		JBrowse link
G Lsm1 LSM1 homolog, mRNA degradation associated decreases expression EXP Phenytoin results in decreased expression of LSM1 mRNA CTD PMID:20345932 NCBI chr16:66,277,345...66,288,852
Ensembl chr16:66,277,345...66,288,852 		JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 increases expression EXP Phenytoin results in increased expression of LTBP4 mRNA CTD PMID:20345932 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178 		JBrowse link
G Lypla1 lysophospholipase 1 increases expression EXP Phenytoin results in increased expression of LYPLA1 mRNA CTD PMID:20345932 NCBI chr 5:19,477,408...19,506,568
Ensembl chr 5:14,679,606...14,708,746 		JBrowse link
G Map1b microtubule-associated protein 1B increases expression ISO Phenytoin results in increased expression of MAP1B mRNA CTD PMID:14741686 NCBI chr 2:32,551,423...32,644,471
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 increases expression EXP Phenytoin results in increased expression of MAP3K4 mRNA CTD PMID:20345932 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO Phenytoin results in decreased phosphorylation of MAPK1 protein CTD PMID:15948689 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO Phenytoin results in decreased phosphorylation of MAPK3 protein CTD PMID:15948689 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 increases expression EXP Phenytoin results in increased expression of MAPRE3 mRNA CTD PMID:20345932 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881 		JBrowse link
G Mbl1 mannose binding lectin 1 decreases expression EXP Phenytoin results in decreased expression of MBL1 mRNA CTD PMID:17381134 NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174 		JBrowse link
G Mdk midkine increases expression ISO Phenytoin results in increased expression of MDK mRNA CTD PMID:14741686 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA CTD PMID:21224054 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Me1 malic enzyme 1 increases expression EXP Phenytoin results in increased expression of ME1 mRNA CTD PMID:17381134 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO Phenytoin results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 increases expression ISO Phenytoin results in increased expression of MESP1 mRNA CTD PMID:26272751 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Mex3d mex-3 RNA binding family member D increases expression EXP Phenytoin results in increased expression of MEX3D mRNA CTD PMID:20345932 NCBI chr 7:9,325,575...9,332,705
Ensembl chr 7:9,325,488...9,332,096 		JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase increases expression EXP Phenytoin results in increased expression of MGAT2 mRNA CTD PMID:20345932 NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases methylation ISO Phenytoin results in increased methylation of MGMT promoter CTD PMID:15949900 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein CTD PMID:21224054 NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp1 matrix metallopeptidase 1 decreases expression
increases expression 		ISO Phenytoin results in decreased expression of MMP1 mRNA
Phenytoin results in increased expression of MMP1 mRNA 		CTD PMID:10914799 PMID:14741686 PMID:15948689 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Phenytoin results in decreased expression of MMP2 mRNA CTD PMID:15948689 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases expression ISO Phenytoin results in decreased expression of MMP3 mRNA CTD PMID:15948689 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mrps18c mitochondrial ribosomal protein S18C increases expression EXP Phenytoin results in increased expression of MRPS18C mRNA CTD PMID:20345932 NCBI chr14:8,812,301...8,818,538
Ensembl chr14:8,791,330...8,818,516 		JBrowse link
G Mtf2 metal response element binding transcription factor 2 increases expression EXP Phenytoin results in increased expression of MTF2 mRNA CTD PMID:20345932 NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524 		JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like increases expression EXP Phenytoin results in increased expression of MTHFD1L mRNA CTD PMID:20345932 NCBI chr 1:40,443,926...40,632,911
Ensembl chr 1:40,444,008...40,632,905 		JBrowse link
G Mtx2 metaxin 2 increases expression EXP Phenytoin results in increased expression of MTX2 mRNA CTD PMID:20345932 NCBI chr 3:59,730,206...59,792,202
Ensembl chr 3:59,730,197...59,792,201 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression
decreases expression 		ISO Phenytoin results in increased expression of MYC protein
Phenytoin results in decreased expression of MYC mRNA 		CTD PMID:10695937 PMID:26272751 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myo1e myosin IE increases expression ISO Phenytoin results in increased expression of MYO1E mRNA CTD PMID:26272751 NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169 		JBrowse link
G Nap1l2 nucleosome assembly protein 1-like 2 affects expression EXP Phenytoin affects the expression of NAP1L2 mRNA CTD PMID:20345932 NCBI chr  X:68,174,051...68,176,449
Ensembl chr  X:68,173,987...68,176,666 		JBrowse link
G Ncan neurocan increases expression ISO Phenytoin results in increased expression of NCAN mRNA CTD PMID:14741686 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436 		JBrowse link
G Ncl nucleolin decreases expression EXP Phenytoin results in decreased expression of NCL mRNA CTD PMID:17381134 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Phenytoin promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein] CTD PMID:21924250 NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Nelfa negative elongation factor complex member A decreases expression EXP Phenytoin results in decreased expression of NELFA mRNA CTD PMID:20345932 NCBI chr14:76,808,920...76,832,998
Ensembl chr14:76,808,870...76,832,994 		JBrowse link
G Nes nestin decreases expression ISO Phenytoin results in decreased expression of NES mRNA CTD PMID:26272751 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Neurog2 neurogenin 2 increases expression ISO Phenytoin results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 2:216,092,709...216,095,276
Ensembl chr 2:216,093,363...216,094,154 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression 		ISO Phenytoin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased localization of and results in increased activity of NFKB1 protein]
Phenytoin results in increased expression of NFKB1 mRNA 		CTD PMID:10700573 PMID:14741686 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases degradation ISO Phenytoin results in decreased degradation of NFKBIA protein CTD PMID:15948689 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngly1 N-glycanase 1 increases expression EXP Phenytoin results in increased expression of NGLY1 mRNA CTD PMID:20345932 NCBI chr15:9,153,738...9,210,228
Ensembl chr15:9,153,738...9,204,630 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of NLRP3 mRNA CTD PMID:23986454 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA CTD PMID:21224054 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npas2 neuronal PAS domain protein 2 increases expression EXP Phenytoin results in increased expression of NPAS2 mRNA CTD PMID:20345932 NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Phenytoin results in increased expression of NQO1 mRNA CTD PMID:17381134 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
affects activity
increases expression
increases activity 		ISO
EXP 		Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]]]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Phenytoin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; NR1I2 protein affects the reaction [Phenytoin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein affects the reaction [Phenytoin results in increased expression of CYP2C9 mRNA]; NR1I2 protein affects the reaction [Phenytoin results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]; Phenytoin binds to and results in increased activity of NR1I2 protein; Phenytoin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]
Phenytoin affects the activity of NR1I2 protein
Phenytoin results in increased expression of NR1I2 protein
Phenytoin results in increased activity of NR1I2 protein 		CTD PMID:12065438 PMID:12695340 PMID:12695351 PMID:14600250 PMID:14977870 More... NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
increases expression
increases activity
increases localization 		ISO
EXP 		[Phenytoin results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; NR1I3 protein affects the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]; Phenytoin promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein]
Phenytoin results in increased expression of NR1I3 protein
NR1I3 protein affects the reaction [Phenytoin results in increased expression of CYP2C29 mRNA]; NR1I3 protein affects the reaction [Phenytoin results in increased expression of CYP2C37 mRNA]
Phenytoin results in increased localization of NR1I3 protein 		CTD PMID:15123723 PMID:15155833 PMID:15849716 PMID:16936065 PMID:17041008 More... NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 increases expression EXP Phenytoin results in increased expression of NR2F1 mRNA CTD PMID:20345932 NCBI chr 2:8,040,375...8,050,123
Ensembl chr 2:8,040,377...8,050,123 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases expression 		ISO
EXP 		Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Phenytoin results in increased expression of CYP2B6 mRNA]]]; NR3C1 protein promotes the reaction [Phenytoin results in increased expression of CYP3A4 mRNA]
Phenytoin results in increased expression of NR3C1 mRNA 		CTD PMID:10219967 PMID:12695351 PMID:20345932 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression ISO Phenytoin results in decreased expression of NRCAM mRNA CTD PMID:26272751 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nsmce3 NSE3 homolog, SMC5-SMC6 complex component increases expression EXP Phenytoin results in increased expression of NSMCE3 mRNA CTD PMID:20345932 NCBI chr 1:118,401,302...118,402,629 JBrowse link
G Nt5dc1 5'-nucleotidase domain containing 1 increases expression EXP Phenytoin results in increased expression of NT5DC1 mRNA CTD PMID:20345932 NCBI chr20:38,105,677...38,208,613
Ensembl chr20:38,105,678...38,208,591 		JBrowse link
G Ntf3 neurotrophin 3 decreases expression ISO Phenytoin results in decreased expression of NTF3 mRNA CTD PMID:7841657 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Nup153 nucleoporin 153 increases expression EXP Phenytoin results in increased expression of NUP153 mRNA CTD PMID:20345932 NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876 		JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO Phenytoin results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr 1:14,081,259...14,083,336
Ensembl chr 1:14,081,328...14,082,149 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO [cyprodime binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Phenytoin CTD PMID:7870991 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 decreases expression ISO Phenytoin results in decreased expression of PAFAH1B1 mRNA CTD PMID:15136057 NCBI chr10:60,031,441...60,090,259
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
G Pafah1b2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 decreases expression ISO Phenytoin results in decreased expression of PAFAH1B2 mRNA CTD PMID:15136057 NCBI chr 8:55,156,778...55,208,800
Ensembl chr 8:46,261,064...46,279,833 		JBrowse link
G Pard6g par-6 family cell polarity regulator gamma increases expression EXP Phenytoin results in increased expression of PARD6G mRNA CTD PMID:20345932 NCBI chr18:73,497,992...73,565,048
Ensembl chr18:73,498,021...73,565,029 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase increases expression EXP Phenytoin results in increased expression of PARG mRNA CTD PMID:20345932 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273 		JBrowse link
G Pax3 paired box 3 decreases expression ISO Phenytoin results in decreased expression of PAX3 mRNA CTD PMID:9118846 PMID:31711903 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042 		JBrowse link
G Pax6 paired box 6 increases expression ISO Phenytoin results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pbx1 PBX homeobox 1 increases expression EXP Phenytoin results in increased expression of PBX1 mRNA CTD PMID:20345932 NCBI chr13:82,811,664...83,121,447
Ensembl chr13:80,278,770...80,588,594 		JBrowse link
G Pcyox1 prenylcysteine oxidase 1 increases expression EXP Phenytoin results in increased expression of PCYOX1 mRNA CTD PMID:20345932 NCBI chr 4:118,832,114...118,842,951
Ensembl chr 4:118,830,638...118,842,951 		JBrowse link
G Pdgfa platelet derived growth factor subunit A increases expression ISO Phenytoin results in increased expression of PDGFA mRNA CTD PMID:14741686 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression EXP
ISO 		Phenytoin results in increased expression of PDGFB mRNA; Phenytoin results in increased expression of PDGFB protein CTD PMID:8463938 PMID:9029455 PMID:14741686 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 increases expression EXP Phenytoin results in increased expression of PGRMC1 mRNA CTD PMID:17381134 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682 		JBrowse link
G Phf14 PHD finger protein 14 increases expression EXP Phenytoin results in increased expression of PHF14 mRNA CTD PMID:20345932 NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885 		JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha increases expression ISO Phenytoin results in increased expression of PIP4K2A mRNA CTD PMID:14741686 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029 		JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression ISO Phenytoin results in decreased expression of PLAUR mRNA CTD PMID:14741686 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plcl1 phospholipase C-like 1 increases expression EXP Phenytoin results in increased expression of PLCL1 mRNA CTD PMID:20345932 NCBI chr 9:56,901,573...57,238,782
Ensembl chr 9:56,901,534...57,238,782 		JBrowse link
G Plec plectin increases expression EXP Phenytoin results in increased expression of PLEC mRNA CTD PMID:20345932 NCBI chr 7:107,887,764...107,949,100
Ensembl chr 7:107,887,764...107,945,467 		JBrowse link
G Pltp phospholipid transfer protein increases expression ISO Phenytoin results in increased expression of PLTP mRNA CTD PMID:15136057 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647 		JBrowse link
G Plxnb2 plexin B2 decreases expression ISO Phenytoin results in decreased expression of PLXNB2 mRNA CTD PMID:14741686 NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330 		JBrowse link
G Pnn pinin, desmosome associated protein increases expression EXP Phenytoin results in increased expression of PNN mRNA CTD PMID:20345932 NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889 		JBrowse link
G Pon1 paraoxonase 1 decreases expression
affects activity 		ISO Phenytoin results in decreased expression of PON1 mRNA
Phenytoin affects the activity of PON1 protein 		CTD PMID:15136057 PMID:28032682 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Por cytochrome p450 oxidoreductase increases activity ISO Phenytoin results in increased activity of POR protein CTD PMID:12051692 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Pou3f1 POU class 3 homeobox 1 increases expression ISO Phenytoin results in increased expression of POU3F1 protein CTD PMID:12781989 NCBI chr 5:136,910,391...136,913,371
Ensembl chr 5:136,910,391...136,913,371 		JBrowse link
G Ppil4 peptidylprolyl isomerase like 4 increases expression EXP Phenytoin results in increased expression of PPIL4 mRNA CTD PMID:20345932 NCBI chr 1:2,273,582...2,305,639
Ensembl chr 1:2,273,609...2,305,632 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2A5 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2B9 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A14 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of RAD50 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TNFSF10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TRADD mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A11 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A4 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of UNG mRNA; PRKDC gene mutant form results in increased susceptibility to [Rifampin co-treated with Phenytoin co-treated with Monocrotaline] CTD PMID:21224054 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prl prolactin decreases expression EXP Phenytoin results in decreased expression of PRL mRNA; Phenytoin results in decreased expression of PRL protein CTD PMID:3734668 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prmt3 protein arginine methyltransferase 3 increases expression EXP Phenytoin results in increased expression of PRMT3 mRNA CTD PMID:20345932 NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435 		JBrowse link
G Prss12 serine protease 12 increases expression ISO Phenytoin results in increased expression of PRSS12 mRNA CTD PMID:14741686 NCBI chr 2:211,624,134...211,684,126
Ensembl chr 2:211,624,134...211,684,126 		JBrowse link
G Psip1 PC4 and SRSF1 interacting protein 1 increases expression EXP Phenytoin results in increased expression of PSIP1 mRNA CTD PMID:20345932 NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 increases expression EXP Phenytoin results in increased expression of PSMC6 mRNA CTD PMID:20345932 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055 		JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 increases expression EXP Phenytoin results in increased expression of PSMD12 mRNA CTD PMID:20345932 NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287 		JBrowse link
G Ptbp2 polypyrimidine tract binding protein 2 increases expression EXP Phenytoin results in increased expression of PTBP2 mRNA CTD PMID:20345932 NCBI chr 2:207,812,659...207,874,019
Ensembl chr 2:207,812,920...207,873,506 		JBrowse link
G Ptch1 patched 1 increases expression ISO Phenytoin results in increased expression of PTCH1 mRNA CTD PMID:16141649 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Phenytoin results in increased expression of PTGS2 mRNA CTD PMID:20345932 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pth parathyroid hormone increases expression ISO Phenytoin results in increased expression of PTH protein CTD PMID:20683115 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Rad50 RAD50 double strand break repair protein multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of RAD50 mRNA CTD PMID:21224054 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396 		JBrowse link
G Rai1 retinoic acid induced 1 increases expression EXP Phenytoin results in increased expression of RAI1 mRNA CTD PMID:20345932 NCBI chr10:44,913,231...45,008,232
Ensembl chr10:44,947,909...45,008,232 		JBrowse link
G Ranbp6 RAN binding protein 6 increases expression EXP Phenytoin results in increased expression of RANBP6 mRNA CTD PMID:20345932 NCBI chr 1:227,572,394...227,576,915
Ensembl chr 1:227,572,105...227,576,942 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 increases expression EXP Phenytoin results in increased expression of RAPGEF4 mRNA CTD PMID:20345932 NCBI chr 3:77,217,024...77,509,933
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Rara retinoic acid receptor, alpha increases expression
decreases expression 		ISO Phenytoin results in increased expression of RARA mRNA
Phenytoin results in decreased expression of RARA mRNA 		CTD PMID:9118846 PMID:9988880 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO Phenytoin results in increased expression of RARB mRNA CTD PMID:9988880 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rarg retinoic acid receptor, gamma increases expression ISO Phenytoin results in increased expression of RARG mRNA CTD PMID:9988880 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Rbm12 RNA binding motif protein 12 increases expression EXP Phenytoin results in increased expression of RBM12 mRNA CTD PMID:20345932 NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915 		JBrowse link
G Rbm3 RNA binding motif protein 3 increases expression EXP Phenytoin results in increased expression of RBM3 mRNA CTD PMID:20345932 NCBI chr  X:14,348,909...14,352,387
Ensembl chr  X:14,348,910...14,353,580 		JBrowse link
G Rbm34 RNA binding motif protein 34 increases expression EXP Phenytoin results in increased expression of RBM34 mRNA CTD PMID:20345932 NCBI chr19:54,936,516...54,956,810
Ensembl chr19:54,936,531...54,956,715 		JBrowse link
G Rbp2 retinol binding protein 2 increases expression ISO Phenytoin results in increased expression of RBP2 mRNA CTD PMID:9118846 NCBI chr 8:99,079,293...99,104,489
Ensembl chr 8:99,079,104...99,104,473 		JBrowse link
G Rdh14 retinol dehydrogenase 14 increases expression EXP Phenytoin results in increased expression of RDH14 mRNA CTD PMID:20345932 NCBI chr 6:33,156,569...33,161,712
Ensembl chr 6:33,156,569...33,161,712 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases activity 		ISO Phenytoin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased localization of and results in increased activity of RELA protein]
Phenytoin results in increased activity of RELA protein 		CTD PMID:10700573 PMID:15322231 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rhoa ras homolog family member A decreases expression ISO Phenytoin results in decreased expression of RHOA mRNA CTD PMID:15136057 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Riok2 RIO kinase 2 increases expression EXP Phenytoin results in increased expression of RIOK2 mRNA CTD PMID:20345932 NCBI chr 1:58,103,132...58,119,397
Ensembl chr 1:58,103,084...58,120,512 		JBrowse link
G Rnaseh1 ribonuclease H1 decreases expression EXP Phenytoin results in decreased expression of RNASEH1 mRNA CTD PMID:20345932 NCBI chr 6:45,282,849...45,292,258
Ensembl chr 6:45,282,854...45,292,236 		JBrowse link
G Rnd1 Rho family GTPase 1 increases expression EXP Phenytoin results in increased expression of RND1 mRNA CTD PMID:20345932 NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399 		JBrowse link
G Rnf115 ring finger protein 115 increases expression EXP Phenytoin results in increased expression of RNF115 mRNA CTD PMID:20345932 NCBI chr 2:186,950,959...187,018,673
Ensembl chr 2:184,262,371...184,329,823 		JBrowse link
G Rpe ribulose-5-phosphate-3-epimerase increases expression EXP Phenytoin results in increased expression of RPE mRNA CTD PMID:20345932 NCBI chr 9:68,191,027...68,211,295
Ensembl chr 9:68,191,292...68,211,591 		JBrowse link
G Rpl28 ribosomal protein L28 increases expression ISO Phenytoin results in increased expression of RPL28 mRNA CTD PMID:14741686 NCBI chr 1:69,052,148...69,054,735
Ensembl chr 1:69,053,203...69,055,032 		JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression EXP Phenytoin results in increased expression of RPS6KA3 mRNA CTD PMID:20345932 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207 		JBrowse link
G Rpsa ribosomal protein SA increases expression ISO Phenytoin results in increased expression of RPSA mRNA CTD PMID:14741686 NCBI chr 8:128,728,761...128,732,736
Ensembl chr 8:119,851,225...119,855,247 		JBrowse link
G Rsrc1 arginine and serine rich coiled-coil 1 decreases expression EXP Phenytoin results in decreased expression of RSRC1 mRNA CTD PMID:20345932 NCBI chr 2:151,226,821...151,632,771
Ensembl chr 2:151,231,156...151,632,765 		JBrowse link
G Ryr2 ryanodine receptor 2 increases expression EXP Phenytoin results in increased expression of RYR2 mRNA CTD PMID:20345932 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142 		JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression ISO Phenytoin results in increased expression of S100A10 mRNA CTD PMID:14741686 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Phenytoin results in increased expression of S100A4 mRNA CTD PMID:14741686 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of S100A8 mRNA CTD PMID:23986454 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions
increases expression 		ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of S100A9 mRNA
Phenytoin results in increased expression of S100A9 mRNA 		CTD PMID:23986454 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sart3 spliceosome associated factor 3, U4/U6 recycling protein increases expression EXP Phenytoin results in increased expression of SART3 mRNA CTD PMID:20345932 NCBI chr12:42,859,026...42,887,041
Ensembl chr12:42,859,305...42,887,038 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Phenytoin results in increased expression of SC5D mRNA CTD PMID:14741686 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Scaf1 SR-related CTD-associated factor 1 increases expression EXP Phenytoin results in increased expression of SCAF1 mRNA CTD PMID:20345932 NCBI chr 1:95,485,448...95,499,389
Ensembl chr 1:95,485,448...95,496,029 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO Phenytoin results in decreased expression of SCARB1 mRNA CTD PMID:15136057 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 affects response to substance ISO SCN1A gene polymorphism affects the susceptibility to Phenytoin; SCN1A protein affects the susceptibility to Phenytoin CTD PMID:15805193 PMID:17001291 NCBI chr 3:50,952,790...51,071,804
Ensembl chr 3:50,952,791...51,071,699 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 affects binding
decreases response to substance
multiple interactions 		ISO Phenytoin binds to [SCN1B protein binds to SCN3A protein]
SCN1B protein mutant form results in decreased susceptibility to Phenytoin
Phenytoin results in decreased activity of [SCN1B protein binds to SCN3A protein] 		CTD PMID:15922564 NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 decreases activity ISO Phenytoin results in decreased activity of SCN2A protein CTD PMID:11212204 NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214 		JBrowse link
G Scn3a sodium voltage-gated channel alpha subunit 3 multiple interactions
affects binding 		ISO Phenytoin results in decreased activity of [SCN1B protein binds to SCN3A protein]
Phenytoin binds to [SCN1B protein binds to SCN3A protein] 		CTD PMID:15922564 NCBI chr 3:50,146,411...50,258,119
Ensembl chr 3:50,148,139...50,258,119 		JBrowse link
G Sdc4 syndecan 4 decreases expression ISO Phenytoin results in decreased expression of SDC4 mRNA CTD PMID:15136057 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Sele selectin E multiple interactions ISO [clobazam co-treated with Phenytoin] results in increased expression of SELE protein CTD PMID:16376047 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Senp7 SUMO specific peptidase 7 increases expression EXP Phenytoin results in increased expression of SENP7 mRNA CTD PMID:20345932 NCBI chr11:44,423,733...44,584,129
Ensembl chr11:44,423,735...44,564,711 		JBrowse link
G Serpinc1 serpin family C member 1 multiple interactions ISO [clobazam co-treated with Phenytoin] results in increased expression of [F2 protein binds to SERPINC1 protein] CTD PMID:16376047 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA CTD PMID:21224054 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 increases expression EXP Phenytoin results in increased expression of SH3YL1 mRNA CTD PMID:20345932 NCBI chr 6:47,522,098...47,565,858
Ensembl chr 6:47,522,091...47,565,858 		JBrowse link
G Shh sonic hedgehog signaling molecule increases expression ISO Phenytoin results in increased expression of SHH mRNA CTD PMID:26272751 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 increases expression EXP Phenytoin results in increased expression of SIAH1A mRNA CTD PMID:20345932 NCBI chr19:36,552,165...36,575,773
Ensembl chr19:20,378,439...20,403,808 		JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 increases expression EXP Phenytoin results in increased expression of SIPA1L1 mRNA CTD PMID:20345932 NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression EXP Phenytoin results in decreased expression of SLC22A7 mRNA CTD PMID:17381134 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921 		JBrowse link
G Slc4a3 solute carrier family 4 member 3 increases expression EXP Phenytoin results in increased expression of SLC4A3 mRNA CTD PMID:20345932 NCBI chr 9:77,036,243...77,053,940
Ensembl chr 9:77,037,016...77,049,105 		JBrowse link
G Smarca1 SNF2 related chromatin remodeling ATPase 1 increases expression EXP Phenytoin results in increased expression of SMARCA1 mRNA CTD PMID:20345932 NCBI chr  X:126,980,201...127,066,385
Ensembl chr  X:126,994,947...127,066,347 		JBrowse link
G Smarca5 SNF2 related chromatin remodeling ATPase 5 increases expression EXP Phenytoin results in increased expression of SMARCA5 mRNA CTD PMID:20345932 NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 increases expression EXP Phenytoin results in increased expression of SMC2 mRNA CTD PMID:20345932 NCBI chr 5:66,806,882...66,853,478
Ensembl chr 5:66,807,011...66,853,242 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 increases expression ISO Phenytoin results in increased expression of SMC3 mRNA CTD PMID:14741686 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522 		JBrowse link
G Smc5 structural maintenance of chromosomes 5 increases expression EXP Phenytoin results in increased expression of SMC5 mRNA CTD PMID:20345932 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096 		JBrowse link
G Snx2 sorting nexin 2 increases expression EXP Phenytoin results in increased expression of SNX2 mRNA CTD PMID:20345932 NCBI chr18:46,602,223...46,643,870
Ensembl chr18:46,602,284...46,643,865 		JBrowse link
G Sp3 Sp3 transcription factor increases expression ISO Phenytoin results in increased expression of SP3 mRNA CTD PMID:14741686 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342 		JBrowse link
G St13 ST13, Hsp70 interacting protein increases expression EXP Phenytoin results in increased expression of ST13 mRNA CTD PMID:17381134 NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 decreases expression ISO Phenytoin results in decreased expression of STAT4 mRNA CTD PMID:14741686 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 decreases expression EXP Phenytoin results in decreased expression of SULT1A1 mRNA CTD PMID:9566755 PMID:17381134 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Sult1d1 sulfotransferase family 1D, member 1 increases expression EXP Phenytoin results in increased expression of SULT1D1 mRNA CTD PMID:20345932 NCBI chr14:20,441,135...20,476,341
Ensembl chr14:20,441,924...20,476,341 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 decreases expression EXP Phenytoin results in decreased expression of SULT2A1 mRNA CTD PMID:9566755 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Syn1 synapsin I multiple interactions
decreases expression 		ISO Thyroxine inhibits the reaction [Phenytoin results in decreased expression of SYN1 mRNA] CTD PMID:27413119 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396 		JBrowse link
G Syp synaptophysin multiple interactions
decreases expression 		ISO Thyroxine inhibits the reaction [Phenytoin results in decreased expression of SYP mRNA] CTD PMID:27413119 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Sypl1 synaptophysin-like 1 increases expression EXP Phenytoin results in increased expression of SYPL1 mRNA CTD PMID:20345932 NCBI chr 6:49,565,111...49,585,205
Ensembl chr 6:49,565,154...49,585,330 		JBrowse link
G Taf9b TATA-box binding protein associated factor 9b increases expression EXP Phenytoin results in increased expression of TAF9B mRNA CTD PMID:20345932 NCBI chr  X:71,289,290...71,300,142
Ensembl chr  X:71,289,290...71,300,604 		JBrowse link
G Tbx21 T-box transcription factor 21 multiple interactions
decreases expression 		ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of TBX21 mRNA
Phenytoin results in decreased expression of TBX21 mRNA 		CTD PMID:23986454 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Tceal1 transcription elongation factor A like 1 increases expression EXP Phenytoin results in increased expression of TCEAL1 mRNA CTD PMID:20345932 NCBI chr  X:100,058,485...100,060,439
Ensembl chr  X:100,058,132...100,060,551 		JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO Phenytoin results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 3:140,638,984...140,644,766
Ensembl chr 3:140,638,984...140,644,766 		JBrowse link
G Terf1 telomeric repeat binding factor 1 increases expression EXP Phenytoin results in increased expression of TERF1 mRNA CTD PMID:20345932 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340 		JBrowse link
G Tgfa transforming growth factor alpha increases expression ISO Phenytoin results in increased expression of TGFA mRNA CTD PMID:9988880 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
decreases expression 		ISO Phenytoin results in increased expression of TGFB1 mRNA
Phenytoin results in decreased expression of TGFB1 mRNA 		CTD PMID:7841657 PMID:9988880 PMID:16141649 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression ISO Phenytoin results in decreased expression of TGFB2 mRNA CTD PMID:9118846 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression ISO Phenytoin results in increased expression of TGFB3 mRNA CTD PMID:14741686 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Thoc6 THO complex subunit 6 decreases expression EXP Phenytoin results in decreased expression of THOC6 mRNA CTD PMID:20345932 NCBI chr10:12,700,051...12,705,411
Ensembl chr10:12,700,051...12,706,925 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Phenytoin results in increased expression of TIMP1 mRNA; Phenytoin results in increased expression of TIMP1 protein CTD PMID:10914799 PMID:14741686 PMID:15948689 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tkt transketolase increases expression EXP Phenytoin results in increased expression of TKT mRNA CTD PMID:17381134 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698 		JBrowse link
G Tlr2 toll-like receptor 2 multiple interactions
increases expression 		ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in increased expression of TLR2 mRNA
Phenytoin results in increased expression of TLR2 mRNA 		CTD PMID:23986454 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions
decreases expression 		ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of TLR4 mRNA
Phenytoin results in decreased expression of TLR4 mRNA 		CTD PMID:23986454 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr9 toll-like receptor 9 multiple interactions
decreases expression 		ISO [Phenytoin co-treated with Buthionine Sulfoximine] results in decreased expression of TLR9 mRNA
Phenytoin results in decreased expression of TLR9 mRNA 		CTD PMID:23986454 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO Phenytoin results in increased expression of TNF mRNA CTD PMID:14741686 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TNFSF10 mRNA CTD PMID:21224054 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO Phenytoin results in increased expression of TP53 mRNA CTD PMID:11134551 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 increases expression EXP Phenytoin results in increased expression of TRP53BP2 mRNA CTD PMID:20345932 NCBI chr13:94,088,769...94,145,436
Ensembl chr13:94,088,709...94,145,432 		JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TRADD mRNA CTD PMID:21224054 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Trmt10b tRNA methyltransferase 10B increases expression EXP Phenytoin results in increased expression of TRMT10B mRNA CTD PMID:20345932 NCBI chr 5:59,548,845...59,572,529
Ensembl chr 5:59,548,869...59,572,526 		JBrowse link
G Tut4 terminal uridylyl transferase 4 increases expression EXP Phenytoin results in increased expression of TUT4 mRNA CTD PMID:20345932 NCBI chr 5:123,201,723...123,306,582
Ensembl chr 5:123,203,003...123,306,465 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP Phenytoin results in increased expression of TXNRD1 mRNA CTD PMID:17381134 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 increases expression EXP Phenytoin results in increased expression of UBE2D2 mRNA CTD PMID:20345932 NCBI chr18:27,638,399...27,680,386
Ensembl chr18:27,364,303...27,406,181 		JBrowse link
G Ubl5 ubiquitin-like 5 decreases expression EXP Phenytoin results in decreased expression of UBL5 mRNA CTD PMID:20345932 NCBI chr 8:19,181,504...19,185,224
Ensembl chr 8:19,181,615...19,185,217 		JBrowse link
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 increases expression EXP Phenytoin results in increased expression of UBR1 mRNA CTD PMID:20345932 NCBI chr 3:128,265,160...128,377,830
Ensembl chr 3:107,811,392...107,922,204 		JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression EXP Phenytoin results in decreased expression of UGDH mRNA CTD PMID:17381134 NCBI chr14:43,202,480...43,226,002
Ensembl chr14:42,848,854...42,872,354 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression
increases activity
multiple interactions
increases expression 		ISO
EXP 		Phenytoin affects the expression of UGT1A1 mRNA
Phenytoin results in increased activity of UGT1A1 protein
Phenytoin results in increased expression of and results in increased activity of UGT1A1 protein
Phenytoin results in increased expression of UGT1A1 mRNA
Phenytoin results in increased expression of UGT1A1 mRNA; Phenytoin results in increased expression of UGT1A1 protein 		CTD PMID:10421657 PMID:15849716 PMID:17381134 PMID:27413119 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression EXP Phenytoin results in increased expression of UGT1A6 mRNA CTD PMID:17381134 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression EXP Phenytoin results in increased expression of UGT2B1 mRNA CTD PMID:17381134 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986 		JBrowse link
G Uncx UNC homeobox decreases expression ISO Phenytoin results in decreased expression of UNCX mRNA CTD PMID:31711903 NCBI chr12:15,092,779...15,097,300
Ensembl chr12:15,092,784...15,097,300 		JBrowse link
G Ung uracil-DNA glycosylase multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of UNG mRNA CTD PMID:21224054 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
G Vars2 valyl-tRNA synthetase 2, mitochondrial increases expression EXP Phenytoin results in increased expression of VARS2 mRNA CTD PMID:20345932 NCBI chr20:3,077,132...3,087,994
Ensembl chr20:3,077,132...3,087,994 		JBrowse link
G Vcan versican increases expression ISO Phenytoin results in increased expression of VCAN mRNA CTD PMID:14741686 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637 		JBrowse link
G Vegfb vascular endothelial growth factor B decreases expression ISO Phenytoin results in decreased expression of VEGFB mRNA CTD PMID:14741686 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
G Vim vimentin increases expression ISO Phenytoin results in increased expression of VIM mRNA CTD PMID:14741686 NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Wnt1 Wnt family member 1 decreases expression ISO Phenytoin results in decreased expression of WNT1 mRNA CTD PMID:7841657 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wnt3 Wnt family member 3 decreases expression ISO Phenytoin results in decreased expression of WNT3 mRNA CTD PMID:26272751 NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099 		JBrowse link
G Wnt5a Wnt family member 5A increases expression ISO Phenytoin results in increased expression of WNT5A mRNA CTD PMID:31711903 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 multiple interactions ISO [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA CTD PMID:21224054 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
G Yme1l1 YME1-like 1 ATPase increases expression EXP Phenytoin results in increased expression of YME1L1 mRNA CTD PMID:20345932 NCBI chr17:85,287,607...85,326,068
Ensembl chr17:85,287,554...85,326,335 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 decreases expression ISO Phenytoin results in decreased expression of ZAP70 mRNA CTD PMID:15136057 NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700 		JBrowse link
G Zfp131 zinc finger protein 131 increases expression EXP Phenytoin results in increased expression of ZFP131 mRNA CTD PMID:20345932 NCBI chr 2:51,722,774...51,753,662
Ensembl chr 2:51,725,541...51,753,639 		JBrowse link
G Zfp503 zinc finger protein 503 increases expression EXP Phenytoin results in increased expression of ZFP503 mRNA CTD PMID:20345932 NCBI chr15:2,313,060...2,316,848
Ensembl chr15:2,313,060...2,316,848 		JBrowse link
G Zfp638 zinc finger protein 638 increases expression EXP Phenytoin results in increased expression of ZFP638 mRNA CTD PMID:20345932 NCBI chr 4:116,355,934...116,475,051
Ensembl chr 4:116,402,428...116,479,845 		JBrowse link
G Zscan21 zinc finger and SCAN domain containing 21 increases expression EXP Phenytoin results in increased expression of ZSCAN21 mRNA CTD PMID:20345932 NCBI chr12:16,998,496...17,024,167
Ensembl chr12:16,998,538...17,013,506 		JBrowse link
sertindole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions 		ISO sertindole results in decreased activity of KCNH2 protein
sertindole inhibits the reaction [KCNH2 protein results in increased transport of Thallium] 		CTD PMID:16278312 PMID:21158687 PMID:24052561 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
sorbinil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO sorbinil inhibits the reaction [AKR1B1 protein results in increased expression of ACTA2 mRNA] CTD PMID:28137510 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 decreases activity
multiple interactions 		ISO sorbinil results in decreased activity of AKR1B1 protein
[sorbinil results in decreased activity of AKR1B1 protein] inhibits the reaction [Lipopolysaccharides results in increased abundance of Reactive Oxygen Species]; [sorbinil results in decreased activity of AKR1B1 protein] inhibits the reaction [Lipopolysaccharides results in increased secretion of Dinoprostone]; [sorbinil results in decreased activity of AKR1B1 protein] which results in decreased susceptibility to Lipopolysaccharides; [sorbinil results in decreased activity of AKR1B1 protein] which results in decreased susceptibility to TNF protein; sorbinil inhibits the reaction [AKR1B1 protein results in decreased expression of CDH1 mRNA]; sorbinil inhibits the reaction [AKR1B1 protein results in increased expression of ACTA2 mRNA]; sorbinil inhibits the reaction [AKR1B1 protein results in increased expression of FN1 mRNA]; sorbinil inhibits the reaction [AKR1B1 protein results in increased expression of FN1 protein]; sorbinil inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]; sorbinil inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein] 		CTD PMID:21334316 PMID:28137510 NCBI chr 4:63,899,222...63,913,315
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 multiple interactions
decreases activity 		ISO sorbinil inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin]; sorbinil inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]
sorbinil results in decreased activity of AKR1B10 protein 		CTD PMID:18325492 PMID:19028477 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 decreases activity EXP sorbinil results in decreased activity of AKR1B8 protein CTD PMID:18845131 NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097 		JBrowse link
G Alb albumin multiple interactions ISO sorbinil inhibits the reaction [[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein] CTD PMID:30682331 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO sorbinil inhibits the reaction [AKR1B1 protein results in decreased expression of CDH1 mRNA] CTD PMID:28137510 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO sorbinil inhibits the reaction [AKR1B1 protein results in increased expression of FN1 mRNA]; sorbinil inhibits the reaction [AKR1B1 protein results in increased expression of FN1 protein] CTD PMID:28137510 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO sorbinil inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; sorbinil inhibits the reaction [TNF protein results in increased secretion of IL6 protein] CTD PMID:21334316 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO sorbinil inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein] CTD PMID:28137510 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO sorbinil inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:28137510 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP sorbinil inhibits the reaction [Streptozocin results in increased expression of NGF mRNA] CTD PMID:9748608 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO sorbinil inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; sorbinil inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] CTD PMID:24021941 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO sorbinil inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 mRNA]; sorbinil inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein] CTD PMID:24021941 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO sorbinil inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of RELA protein]; sorbinil inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein] CTD PMID:24021941 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP sorbinil inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA] CTD PMID:9748608 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [sorbinil results in decreased activity of AKR1B1 protein] which results in decreased susceptibility to TNF protein; sorbinil inhibits the reaction [[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein]; sorbinil inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; sorbinil inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]; sorbinil inhibits the reaction [TNF protein results in increased secretion of Dinoprostone]; sorbinil inhibits the reaction [TNF protein results in increased secretion of IL6 protein]
sorbinil inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; sorbinil inhibits the reaction [Oxygen deficiency results in increased expression of TNF protein] 		CTD PMID:21334316 PMID:24021941 PMID:30682331 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO sorbinil inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein] CTD PMID:30682331 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
sulfinpyrazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity 		ISO Sulfinpyrazone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Sulfinpyrazone results in decreased activity of ABCB11 protein 		CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions 		ISO
EXP 		Sulfinpyrazone results in decreased activity of ABCC1 protein
[Sulfinpyrazone results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine 		CTD PMID:12893836 PMID:15044619 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity ISO Sulfinpyrazone results in decreased activity of ABCC2 protein CTD PMID:14569069 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Sulfinpyrazone results in increased expression of CYP2B6 protein CTD PMID:14977870 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Sulfinpyrazone results in decreased activity of CYP2C8 protein CTD PMID:12464242
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
increases activity 		ISO Sulfinpyrazone results in increased expression of CYP3A4 mRNA
Sulfinpyrazone results in increased activity of CYP3A4 protein 		CTD PMID:9512926 PMID:10219967 PMID:12065438 PMID:16837568 PMID:17954527 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine] CTD PMID:15044619 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Sulfinpyrazone inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide] CTD PMID:15999103 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity 		ISO Sulfinpyrazone binds to and results in increased activity of NR1I2 protein
Sulfinpyrazone results in increased activity of NR1I2 protein 		CTD PMID:12065438 PMID:14977870 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Sulfinpyrazone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid] CTD PMID:21272127 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555 		JBrowse link
suxibuzone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pklr pyruvate kinase L/R decreases activity EXP suxibuzone results in decreased activity of PKLR protein CTD PMID:3107799 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    chemical entity 20843
      atom 20843
        nonmetal atom 20751
          nitrogen atom 19576
            nitrogen molecular entity 19576
              organonitrogen compound 19382
                organonitrogen heterocyclic compound 18513
                  diazolidine 1051
                    imidazolidines + 1041
                    pyrazolidines + 29
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    p-block element atom 20766
                      carbon group element atom 20699
                        carbon atom 20693
                          organic molecular entity 20693
                            organic molecule 20637
                              organic cyclic compound 20387
                                organic heterocyclic compound 19369
                                  organic heteromonocyclic compound 18157
                                    diazolidine 1051
                                      imidazolidines + 1041
                                      pyrazolidines + 29
paths to the root