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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
EXP |
[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in decreased phosphorylation of AKT1 protein]; [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased cleavage of AKT1 protein]; Biotin inhibits the reaction [Aluminum Chloride results in decreased phosphorylation of AKT1 protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased cleavage of AKT1 protein] |
CTD |
PMID:32383521 |
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NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
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G |
App |
amyloid beta precursor protein |
multiple interactions |
EXP |
[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of APP protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of APP protein] |
CTD |
PMID:32383521 |
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NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
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G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
decreases expression |
ISO |
Biotin results in decreased expression of CXCL11 mRNA |
CTD |
PMID:15219929 |
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NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions increases expression |
ISO |
Biotin results in increased expression of and results in increased activity of CYP1B1 protein Biotin results in increased expression of CYP1B1 mRNA |
CTD |
PMID:15219929 PMID:15333708 |
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NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions |
ISO |
Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] |
CTD |
PMID:9143349 |
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NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
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G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
multiple interactions |
ISO |
[Chromium co-treated with Biotin] results in decreased expression of HBA1 protein modified form; [chromium tripicolinate co-treated with Biotin] results in decreased expression of HBA1 protein modified form |
CTD |
PMID:17684468 |
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NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
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G |
Herc4 |
HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
increases expression |
ISO |
Biotin results in increased expression of HERC4 mRNA |
CTD |
PMID:15219929 |
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NCBI chr20:26,755,948...26,831,267
Ensembl chr20:26,755,911...26,830,931
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G |
Hira |
histone cell cycle regulator |
decreases expression |
ISO |
Biotin results in decreased expression of HIRA mRNA |
CTD |
PMID:15219929 |
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NCBI chr11:86,168,196...86,276,430
Ensembl chr11:86,168,196...86,276,430
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G |
Ighg1 |
immunoglobulin heavy constant gamma 1 |
increases expression |
ISO |
Biotin results in increased expression of IGHG1 mRNA |
CTD |
PMID:15219929 |
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NCBI chr 6:139,140,572...139,784,388
Ensembl chr 6:139,140,679...139,142,218
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
EXP |
[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein] |
CTD |
PMID:32383521 |
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NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
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G |
Il6 |
interleukin 6 |
multiple interactions |
EXP |
[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of IL6 protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of IL6 protein] |
CTD |
PMID:32383521 |
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NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
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G |
Irs1 |
insulin receptor substrate 1 |
multiple interactions |
EXP |
[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride affects the phosphorylation of IRS1 protein]; Biotin inhibits the reaction [Aluminum Chloride affects the phosphorylation of IRS1 protein] |
CTD |
PMID:32383521 |
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NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
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G |
Lamp1 |
lysosomal-associated membrane protein 1 |
decreases expression |
ISO |
Biotin results in decreased expression of LAMP1 mRNA |
CTD |
PMID:15219929 |
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NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
increases expression |
ISO |
Biotin results in increased expression of PPARGC1A mRNA |
CTD |
PMID:23056435 |
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NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
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G |
Sele |
selectin E |
affects binding |
ISO |
[Acetylglucosamine analog binds to Biotin] which binds to SELE protein |
CTD |
PMID:12191509 |
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NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
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G |
Sell |
selectin L |
affects binding |
EXP |
[Acetylglucosamine analog binds to Biotin] which binds to SELL protein |
CTD |
PMID:12191509 |
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NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
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G |
Selp |
selectin P |
affects binding |
ISO |
[Acetylglucosamine analog binds to Biotin] which binds to SELP protein |
CTD |
PMID:12191509 |
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NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
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G |
Slc5a6 |
solute carrier family 5 member 6 |
affects expression increases transport multiple interactions increases uptake |
ISO EXP |
Biotin affects the expression of SLC5A6 mRNA; Biotin affects the expression of SLC5A6 protein SLC5A6 results in increased transport of Biotin Sodium affects the reaction [SLC5A6 results in increased transport of Biotin]; Thioctic Acid inhibits the reaction [SLC5A6 results in increased transport of Biotin] 2,4-Dinitrophenol inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; 4-Chloromercuribenzenesulfonate inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Azides inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; calmidazolium inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; chelerythrine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Gramicidin inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Iodoacetates inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Ouabain inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Probenecid inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Sodium affects the reaction [SLC5A6 results in increased transport of Biotin]; Sodium promotes the reaction [SLC5A6 protein results in increased transport of Biotin]; Staurosporine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Tetradecanoylphorbol Acetate promotes the reaction [SLC5A6 protein results in increased transport of Biotin]; Trifluoperazine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] SLC5A6 results in increased uptake of Biotin SLC5A6 protein results in increased transport of Biotin; SLC5A6 results in increased transport of Biotin |
CTD |
PMID:9516450 PMID:10329687 PMID:10516089 PMID:12646417 PMID:15561972 |
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NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116
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G |
Tmprss15 |
transmembrane serine protease 15 |
increases expression |
ISO |
Biotin results in increased expression of TMPRSS15 mRNA |
CTD |
PMID:15219929 |
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NCBI chr11:17,561,591...17,684,903
Ensembl chr11:17,561,596...17,684,903
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
EXP |
[Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of TNF protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of TNF protein] |
CTD |
PMID:32383521 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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G |
Tpr |
translocated promoter region, nuclear basket protein |
increases expression |
ISO |
Biotin results in increased expression of TPR mRNA |
CTD |
PMID:15219929 |
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NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
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