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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pyrrolidines
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Accession:CHEBI:38260 term browser browse the term
Definition:Any of a class of heterocyclic amines having a saturated five-membered ring.
Synonyms:alt_id: CHEBI:26922;   CHEBI:38191;   MESH:D011759
 xref_mesh: MESH:D011759

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      CHEBI ontology 19812
        chemical entity 19812
          atom 19811
            nonmetal atom 19698
              nitrogen atom 18761
                nitrogen molecular entity 18761
                  organonitrogen compound 18533
                    organonitrogen heterocyclic compound 17639
                      pyrrolidines 2265
                        (+)-Nornicotine 0
                        (2R,3R)-1-(2,3-dihydro-1H-inden-2-yl)-2-[4-(hydroxymethyl)-2-iodophenyl]-3-[(4-methylphenyl)thio]-5-oxo-N-propan-2-yl-3-pyrrolidinecarboxamide 0
                        (2R,3R)-1-(2,3-dihydro-1H-inden-2-yl)-2-[4-(hydroxymethyl)-2-iodophenyl]-3-[(4-methylphenyl)thio]-N-[2-(4-morpholinyl)ethyl]-5-oxo-3-pyrrolidinecarboxamide 0
                        (3R)-3-(2-fluoro-5-methylphenyl)-7-phenyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                        (3R)-7-phenyl-2-(phenylmethyl)-3-[4-(trifluoromethyl)phenyl]-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                        (3R,3aS,7R,7aS)-3-[5-(1-benzothiophen-2-yl)-2-methoxyphenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                        (3R,3aS,7R,7aS)-7-methyl-3-(2-naphthalenyl)-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                        (3S,6S,7R,8aR)-6-(4-hydroxyphenyl)-N-[5-[(2-mercapto-1-oxoethyl)amino]pentyl]-3-(2-methylpropyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                        (3S,6S,7R,8aR)-6-[3-(2-hydroxyethoxy)phenyl]-N-[5-[(2-mercapto-1-oxoethyl)amino]pentyl]-3-(2-methylpropyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                        (3aR,6aR)-5-(3-methoxyphenyl)-3-[oxo(2-pyrazinyl)methyl]-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione 0
                        (3aR,6aS)-3-(2-chlorophenyl)-5-(2,5-dimethoxyphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione 0
                        (3aR,6aS)-3-(3,4-dimethoxyphenyl)-5-(2,4-dimethylphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione 0
                        (5-tert-butyl-1,3,4-oxadiazol-2-yl)[(2R)-pyrrolidin-2-yl]methanone 0
                        (6R,7S,8aS)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxylic acid 0
                        (6R,7S,8aS)-N-(5-aminopentyl)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                        (6S,7R,8aR)-N-[6-(dimethylamino)hexyl]-6-[3-(2-hydroxyethoxy)phenyl]-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                        (S)-2-(methoxymethyl)pyrrolidine 0
                        1-(1-pyrrolidinyl)-1-octadecanone 0
                        1-(2,4-dinitroanilino)-3-(4-propan-2-yloxyphenyl)pyrrolidine-2,5-dione 0
                        1-(2,6-dimethylphenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]thiourea 0
                        1-(2-furanylmethyl)-4-[oxo(thiophen-2-yl)methyl]-5-phenylpyrrolidine-2,3-dione 0
                        1-(2-hydroxyethyl)pyrrolidinium + 0
                        1-(3,4-dimethylphenyl)-3-(2-pyrimidinylthio)pyrrolidine-2,5-dione 0
                        1-(3,5-dichlorophenyl)-3-(4-morpholinyl)pyrrolidine-2,5-dione 0
                        1-(3,5-dichlorophenyl)-3-(N-hydroxyanilino)pyrrolidine-2,5-dione 0
                        1-(3,5-dimethylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione 0
                        1-(3,5-dimethylphenyl)-4-(1-ethyl-2-benzimidazolyl)-2-pyrrolidinone 0
                        1-(3-chloro-4-fluorophenyl)-4-[(4-methyl-1-piperazinyl)-oxomethyl]-2-pyrrolidinone 0
                        1-(3-chloro-4-methylphenyl)-5-oxo-N-(2-thiazolyl)-3-pyrrolidinecarboxamide 0
                        1-(4-Methylphenyl)pyrrolidine-2,5-dione 0
                        1-(4-bromophenyl)-3-(diethylamino)pyrrolidine-2,5-dione 0
                        1-(4-bromophenyl)-N-(3,4-dichlorophenyl)-5-oxo-3-pyrrolidinecarboxamide 0
                        1-(4-chlorophenyl)-2-[5-(1-pyrrolidinyl)-2-tetrazolyl]ethanone oxime 0
                        1-(4-chlorophenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]urea 0
                        1-(4-ethoxyphenyl)-3-[(1,3,3-trimethyl-2-indolylidene)methyl]pyrrolidine-2,5-dione 0
                        1-(4-ethoxyphenyl)-3-[methyl-(phenylmethyl)amino]pyrrolidine-2,5-dione 0
                        1-(4-methoxyphenyl)-3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)pyrrolidine-2,5-dione 0
                        1-(4-methoxyphenyl)-N'-[(3-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-5-oxo-3-pyrrolidinecarbohydrazide 0
                        1-(4-methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide 0
                        1-(4-methylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione 0
                        1-(4-nitrophenyl)-3-[(1,3,3-trimethyl-2-indolylidene)methyl]pyrrolidine-2,5-dione 0
                        1-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-(5-pyrrolidin-2-yl-1H-pyrazol-3-yl)urea 0
                        1-[1-(3-chloro-4-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-4-piperidinecarboxamide 0
                        1-[1-(3-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-4-piperidinecarboxamide 0
                        1-[4-[2-(2-propan-2-ylidenehydrazinyl)-4-thiazolyl]phenyl]pyrrolidine-2,5-dione 0
                        1-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(2,4,6-trimethylphenyl)thiourea 0
                        2'-Hydroxynicotine 0
                        2,2-dimethyl-3-(4-methoxyphenyl)-4-ethyl-6-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol 0
                        2,2-dimethyl-3-(4-methoxyphenyl)-4-ethyl-8-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol 0
                        2-(1-Pyrrolidinyl)-2-cyclopenten-1-one 0
                        2-(3-nitrophenyl)-4,5-dioxo-1-phenyl-3-pyrrolidinecarboxylic acid ethyl ester 0
                        2-(4-methoxyphenyl)-4,5-dioxo-1-(4-sulfamoylphenyl)-3-pyrrolidinecarboxylic acid ethyl ester 0
                        2-(pyridin-4-yl)-4-(pyrrolidin-1-yl)quinazoline 0
                        2-Acetylpyrrolidine 0
                        2-[4-(cyclohexylamino)-3-nitrophenyl]-5-methyl-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione 0
                        2-[4-[2-(4-chlorophenyl)ethylamino]-3-nitrophenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-dione 0
                        2-[7-oxo-7-(3-phenyl-1-pyrrolidinyl)heptyl]isoindole-1,3-dione 0
                        2-[[1-(4-ethoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]amino]acetonitrile 0
                        2-[[1-(4-methoxy-2-nitrophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]benzoic acid 0
                        2-methyl-3-(pyrrolidin-1-yl)-1-[4-(trifluoromethyl)phenyl]propan-1-one + 0
                        2-methylpyrrolidine + 1
                        3',4'-difluoro-N-\{4'-fluoro-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-yl\}-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-carboxamide 0
                        3'-Hydroxycotinine, Cis- 0
                        3,3,5,5-Tetramethylpyrroline-N-oxide 0
                        3,4-Dimethyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                        3-(1,3-benzothiazol-2-ylhydrazo)-1-(4-ethylphenyl)pyrrolidine-2,5-dione 0
                        3-(1-ethyl-2-pyrrolidinyl)pyridine 0
                        3-(1H-indol-3-yl)-1-phenylpyrrolidine-2,5-dione 0
                        3-(2-pyrimidinylthio)-1-[2-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione 0
                        3-(4-methylphenyl)-N-phenyl-1-pyrrolidinecarboxamide 0
                        3-Ethyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                        3-Methyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                        3-[(1-methyl-5-tetrazolyl)thio]-1-phenylpyrrolidine-2,5-dione 0
                        3-[1-(2,4-dichlorophenyl)sulfonyl-2-pyrrolidinyl]pyridine 0
                        3-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-phenylpyrrolidine-2,5-dione 0
                        3-[4-(dimethylamino)phenyl]-1-[1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl]-1-[(1,3,5-trimethyl-4-pyrazolyl)methyl]thiourea 0
                        3-amino-N-(2-chlorophenyl)-4-(1-pyrrolidinyl)benzenesulfonamide 0
                        3-benzoyl-1,5-bis(2-methoxyphenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione 0
                        3-ethynyl-5-(1-methyl-2-pyrrolidinyl)pyridine 0
                        3a-hydroxy-5-(2-methylbut-2-enylidene)-1-phenyl-3,6-dihydro-2H-pyrrolo[2,3-b]pyridin-4-one 0
                        4,5-dioxo-2-phenyl-1-(4-sulfamoylphenyl)-3-pyrrolidinecarboxylic acid ethyl ester 0
                        4-(1-benzofuran-2-carbonyl)-1-(5-methyl-1,2-oxazol-3-yl)-5-(3-prop-2-enoxyphenyl)pyrrolidine-2,3-dione 0
                        4-(furan-2-carbonyl)-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(4-propan-2-ylphenyl)pyrrolidine-2,3-dione 0
                        4-Chloro-2-(5-methyl-1,3-dioxooctahydro-2H-isoindol-2-yl)phenyl 2-furoate 0
                        4-[(3S,6R,7S,8aS)-7-[[(4-fluorophenyl)methylamino]-oxomethyl]-6-[3-(2-hydroxyethoxy)phenyl]-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-3-yl]butyl-trimethylammonium 0
                        4-[2-benzofuranyl(oxo)methyl]-1-[2-(4-morpholinyl)ethyl]-5-(3-pyridinyl)pyrrolidine-2,3-dione 0
                        4-[3-(2,5-dimethyl-1-pyrrolyl)-4-(1-pyrrolidinyl)phenyl]sulfonylmorpholine 0
                        4-[[[(2S,3R,5aS,10aS)-3-(4-hydroxyphenyl)-5,10-dioxo-1,2,3,5a,6,7,8,10a-octahydrodipyrrolo[1,2-c:1',3'-f]pyrazin-2-yl]-oxomethyl]amino]butyl-trimethylammonium 0
                        4-[[[(3S,6R,7S,8aS)-3-(4-acetamidobutyl)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-7-yl]-oxomethyl]amino]butyl-trimethylammonium 0
                        4-acetyl-1-[2-(1H-indol-3-yl)ethyl]-5-(3-methoxyphenyl)pyrrolidine-2,3-dione 0
                        5'-Hydroxycotinine 0
                        5-(2,4-dichlorophenyl)-4,6-dioxo-3a,6a-dihydro-2H-pyrrolo[3,4-d]isoxazole-3,3-dicarboxylic acid dimethyl ester 0
                        5-(2-fluorophenyl)-4-(2-methyl-2,3-dihydro-1-benzofuran-5-carbonyl)-1-(2-morpholin-4-ylethyl)pyrrolidine-2,3-dione 0
                        5-(3,4-dimethoxyphenyl)-4-(furan-2-carbonyl)-1-(2-phenylethyl)pyrrolidine-2,3-dione 0
                        5-(3-bromophenyl)-1-(furan-2-ylmethyl)-4-(5-methylfuran-2-carbonyl)pyrrolidine-2,3-dione 0
                        5-(3-butoxyphenyl)-1-(pyridin-3-ylmethyl)-4-(thiophene-2-carbonyl)pyrrolidine-2,3-dione 0
                        5-(4-butoxyphenyl)-1-(furan-2-ylmethyl)-4-(5-methylfuran-2-carbonyl)pyrrolidine-2,3-dione 0
                        5-(4-ethoxyphenyl)-1,3-diphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione 0
                        5-Ethyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                        5-Methyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                        5-[[2,5-dimethoxy-4-(1-pyrrolidinyl)phenyl]methylidene]-3-methylthiazolidine-2,4-dione 0
                        5-chloro-6-\{[(2Z)-2-iminopyrrolidin-1-yl]methyl\}uracil 0
                        8-(4-hydroxy-3-methoxyphenyl)-6-(4-methylphenyl)-3,4a,7a,8-tetrahydropyrrolo[2,3]thiopyrano[4,5-b]thiazole-2,5,7-trione 0
                        8-\{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl\}-5,7-dimethoxy-4-pentyl-2H-chromen-2-one 0
                        Aganepag isopropyl 0
                        Anhwiedelphinine 0
                        BMS-754807 8
                        Codonopsine 0
                        FR901469 0
                        LSM-16571 0
                        LSM-18969 0
                        LSM-26452 0
                        LSM-26959 0
                        LSM-27159 0
                        LSM-27979 0
                        LSM-28138 0
                        LSM-28426 0
                        LSM-28442 0
                        LSM-32103 0
                        LSM-32133 0
                        LSM-32492 0
                        Lansimide 3 0
                        MI-63 0
                        Maltoxazine 0
                        Mesembrenone 0
                        Mesembrine 0
                        Mesembrinol 0
                        N'-Hydroxymethylnorcotinine 0
                        N'-Nitrosonornicotine 13
                        N'-[(3-bromo-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-2-(2-oxo-4-phenyl-1-pyrrolidinyl)acetohydrazide 0
                        N,3-diphenyl-1-pyrrolidinecarboxamide 0
                        N,N'-diphenylcarbamimidothioic acid [1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl] ester 0
                        N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide 0
                        N,N-dipropyl-2-(pyrrolidin-1-yl)quinazolin-4-amine 0
                        N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine + 0
                        N-(2,4-dinitrophenyl)-L-proline 0
                        N-(2,4-dinitrophenyl)proline 0
                        N-(3,5-Dichlorophenyl)succinimide 1
                        N-(4-methyl-2-pyridinyl)-2-[3-(trifluoromethyl)phenyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carbothioamide 0
                        N-(\{(2S,4R)-4-[(4-chlorobenzyl)oxy]pyrrolidin-2-yl\}methyl)isoquinoline-5-sulfonamide 0
                        N-Methylnicotinium 0
                        N-Nitrosopyrrolidine 796
                        N-[(1,5-dimethyl-2-pyrrolyl)methyl]-1-(4-methylphenyl)-5-oxo-3-pyrrolidinecarboxamide 0
                        N-[3-[2,5-dioxo-3-(phenylmethyl)-1-pyrrolidinyl]phenyl]acetamide 0
                        N-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzenesulfonamide 0
                        N-acylpyrrolidine + 47
                        N-alkylpyrrolidine + 1182
                        N-benzyl-2-(2,6-dimethylphenoxy)-N-[((3R,4S)-4-\{[isobutyl(phenylsulfonyl)amino]methyl\}pyrrolidin-3-yl)methyl]acetamide 0
                        N-butyl-N-[2,5-dioxo-1-(4-propoxyphenyl)-3-pyrrolidinyl]acetamide 0
                        Norcotinine 0
                        Phensuximide 0
                        SLM6071469 0
                        allyl \{(1S)-1-[(5-\{4-[(2,3-dihydro-1H-inden-2-ylamino)carbonyl]benzyl\}-1,2,4-oxadiazol-3-yl)carbonyl]-3-pyrrolidin-3-ylpropyl\}carbamate 0
                        aminopyrrolidine + 0
                        amisulpride 3
                        atrasentan 13
                        bepridil + 9
                        beta-Homoproline 0
                        clemizole 11
                        darifenacin + 3
                        epolamine 0
                        eribaxaban 0
                        ficellomycin 0
                        fluoropyrrolidine + 0
                        flurochloridone 0
                        hydroxypyrrolidine + 91
                        methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate 0
                        methyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate 0
                        methyl 5-(hydroxymethyl)pyrrolidine-2-carboxylate 0
                        methyl 5-(hydroxymethyl)pyrrolidine-3-carboxylate 0
                        miboplatin 0
                        nafadotride 3
                        nicotine bitartrate 0
                        ombitasvir + 0
                        phyllospadine 0
                        picilorex 0
                        piromidic acid 0
                        procyclidine + 13
                        proline + 273
                        prolinols + 0
                        pyrrolidin-2-ylmethylamine + 0
                        pyrrolidine + 2
                        pyrrolidine N-oxides + 0
                        pyrrolidine alkaloid + 1119
                        pyrrolidine dithiocarbamate 207
                        pyrrolidinecarbaldehyde + 0
                        pyrrolidinecarbohydrazide + 0
                        pyrrolidinecarbonitrile + 0
                        pyrrolidinecarboxamide + 32
                        pyrrolidinecarboxylic acid + 238
                        pyrrolidinehydroxamic acid + 0
                        pyrrolidinesulfonic acid + 0
                        pyrrolidinone + 166
                        pyrrolidinoquinazoline + 0
                        rolicyclidine 0
                        suclofenide 0
                        tipiracil 0
                        trans-4,5-Dimethyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                        vibegron 0
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19812
        subatomic particle 19811
          composite particle 19811
            hadron 19811
              baryon 19811
                nucleon 19811
                  atomic nucleus 19811
                    atom 19811
                      main group element atom 19708
                        p-block element atom 19708
                          carbon group element atom 19630
                            carbon atom 19620
                              organic molecular entity 19620
                                organic molecule 19560
                                  organic cyclic compound 19351
                                    organic heterocyclic compound 18582
                                      organic heteromonocyclic compound 17081
                                        pyrrolidines 2265
                                          (+)-Nornicotine 0
                                          (2R,3R)-1-(2,3-dihydro-1H-inden-2-yl)-2-[4-(hydroxymethyl)-2-iodophenyl]-3-[(4-methylphenyl)thio]-5-oxo-N-propan-2-yl-3-pyrrolidinecarboxamide 0
                                          (2R,3R)-1-(2,3-dihydro-1H-inden-2-yl)-2-[4-(hydroxymethyl)-2-iodophenyl]-3-[(4-methylphenyl)thio]-N-[2-(4-morpholinyl)ethyl]-5-oxo-3-pyrrolidinecarboxamide 0
                                          (3R)-3-(2-fluoro-5-methylphenyl)-7-phenyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                                          (3R)-7-phenyl-2-(phenylmethyl)-3-[4-(trifluoromethyl)phenyl]-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                                          (3R,3aS,7R,7aS)-3-[5-(1-benzothiophen-2-yl)-2-methoxyphenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                                          (3R,3aS,7R,7aS)-7-methyl-3-(2-naphthalenyl)-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                                          (3S,6S,7R,8aR)-6-(4-hydroxyphenyl)-N-[5-[(2-mercapto-1-oxoethyl)amino]pentyl]-3-(2-methylpropyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                                          (3S,6S,7R,8aR)-6-[3-(2-hydroxyethoxy)phenyl]-N-[5-[(2-mercapto-1-oxoethyl)amino]pentyl]-3-(2-methylpropyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                                          (3aR,6aR)-5-(3-methoxyphenyl)-3-[oxo(2-pyrazinyl)methyl]-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione 0
                                          (3aR,6aS)-3-(2-chlorophenyl)-5-(2,5-dimethoxyphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione 0
                                          (3aR,6aS)-3-(3,4-dimethoxyphenyl)-5-(2,4-dimethylphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione 0
                                          (5-tert-butyl-1,3,4-oxadiazol-2-yl)[(2R)-pyrrolidin-2-yl]methanone 0
                                          (6R,7S,8aS)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxylic acid 0
                                          (6R,7S,8aS)-N-(5-aminopentyl)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                                          (6S,7R,8aR)-N-[6-(dimethylamino)hexyl]-6-[3-(2-hydroxyethoxy)phenyl]-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                                          (S)-2-(methoxymethyl)pyrrolidine 0
                                          1-(1-pyrrolidinyl)-1-octadecanone 0
                                          1-(2,4-dinitroanilino)-3-(4-propan-2-yloxyphenyl)pyrrolidine-2,5-dione 0
                                          1-(2,6-dimethylphenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]thiourea 0
                                          1-(2-furanylmethyl)-4-[oxo(thiophen-2-yl)methyl]-5-phenylpyrrolidine-2,3-dione 0
                                          1-(2-hydroxyethyl)pyrrolidinium + 0
                                          1-(3,4-dimethylphenyl)-3-(2-pyrimidinylthio)pyrrolidine-2,5-dione 0
                                          1-(3,5-dichlorophenyl)-3-(4-morpholinyl)pyrrolidine-2,5-dione 0
                                          1-(3,5-dichlorophenyl)-3-(N-hydroxyanilino)pyrrolidine-2,5-dione 0
                                          1-(3,5-dimethylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione 0
                                          1-(3,5-dimethylphenyl)-4-(1-ethyl-2-benzimidazolyl)-2-pyrrolidinone 0
                                          1-(3-chloro-4-fluorophenyl)-4-[(4-methyl-1-piperazinyl)-oxomethyl]-2-pyrrolidinone 0
                                          1-(3-chloro-4-methylphenyl)-5-oxo-N-(2-thiazolyl)-3-pyrrolidinecarboxamide 0
                                          1-(4-Methylphenyl)pyrrolidine-2,5-dione 0
                                          1-(4-bromophenyl)-3-(diethylamino)pyrrolidine-2,5-dione 0
                                          1-(4-bromophenyl)-N-(3,4-dichlorophenyl)-5-oxo-3-pyrrolidinecarboxamide 0
                                          1-(4-chlorophenyl)-2-[5-(1-pyrrolidinyl)-2-tetrazolyl]ethanone oxime 0
                                          1-(4-chlorophenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]urea 0
                                          1-(4-ethoxyphenyl)-3-[(1,3,3-trimethyl-2-indolylidene)methyl]pyrrolidine-2,5-dione 0
                                          1-(4-ethoxyphenyl)-3-[methyl-(phenylmethyl)amino]pyrrolidine-2,5-dione 0
                                          1-(4-methoxyphenyl)-3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)pyrrolidine-2,5-dione 0
                                          1-(4-methoxyphenyl)-N'-[(3-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-5-oxo-3-pyrrolidinecarbohydrazide 0
                                          1-(4-methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide 0
                                          1-(4-methylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione 0
                                          1-(4-nitrophenyl)-3-[(1,3,3-trimethyl-2-indolylidene)methyl]pyrrolidine-2,5-dione 0
                                          1-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-(5-pyrrolidin-2-yl-1H-pyrazol-3-yl)urea 0
                                          1-[1-(3-chloro-4-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-4-piperidinecarboxamide 0
                                          1-[1-(3-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-4-piperidinecarboxamide 0
                                          1-[4-[2-(2-propan-2-ylidenehydrazinyl)-4-thiazolyl]phenyl]pyrrolidine-2,5-dione 0
                                          1-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(2,4,6-trimethylphenyl)thiourea 0
                                          2'-Hydroxynicotine 0
                                          2,2-dimethyl-3-(4-methoxyphenyl)-4-ethyl-6-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol 0
                                          2,2-dimethyl-3-(4-methoxyphenyl)-4-ethyl-8-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol 0
                                          2-(1-Pyrrolidinyl)-2-cyclopenten-1-one 0
                                          2-(3-nitrophenyl)-4,5-dioxo-1-phenyl-3-pyrrolidinecarboxylic acid ethyl ester 0
                                          2-(4-methoxyphenyl)-4,5-dioxo-1-(4-sulfamoylphenyl)-3-pyrrolidinecarboxylic acid ethyl ester 0
                                          2-(pyridin-4-yl)-4-(pyrrolidin-1-yl)quinazoline 0
                                          2-Acetylpyrrolidine 0
                                          2-[4-(cyclohexylamino)-3-nitrophenyl]-5-methyl-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione 0
                                          2-[4-[2-(4-chlorophenyl)ethylamino]-3-nitrophenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-dione 0
                                          2-[7-oxo-7-(3-phenyl-1-pyrrolidinyl)heptyl]isoindole-1,3-dione 0
                                          2-[[1-(4-ethoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]amino]acetonitrile 0
                                          2-[[1-(4-methoxy-2-nitrophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]benzoic acid 0
                                          2-methyl-3-(pyrrolidin-1-yl)-1-[4-(trifluoromethyl)phenyl]propan-1-one + 0
                                          2-methylpyrrolidine + 1
                                          3',4'-difluoro-N-\{4'-fluoro-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-yl\}-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-carboxamide 0
                                          3'-Hydroxycotinine, Cis- 0
                                          3,3,5,5-Tetramethylpyrroline-N-oxide 0
                                          3,4-Dimethyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                                          3-(1,3-benzothiazol-2-ylhydrazo)-1-(4-ethylphenyl)pyrrolidine-2,5-dione 0
                                          3-(1-ethyl-2-pyrrolidinyl)pyridine 0
                                          3-(1H-indol-3-yl)-1-phenylpyrrolidine-2,5-dione 0
                                          3-(2-pyrimidinylthio)-1-[2-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione 0
                                          3-(4-methylphenyl)-N-phenyl-1-pyrrolidinecarboxamide 0
                                          3-Ethyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                                          3-Methyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                                          3-[(1-methyl-5-tetrazolyl)thio]-1-phenylpyrrolidine-2,5-dione 0
                                          3-[1-(2,4-dichlorophenyl)sulfonyl-2-pyrrolidinyl]pyridine 0
                                          3-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-phenylpyrrolidine-2,5-dione 0
                                          3-[4-(dimethylamino)phenyl]-1-[1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl]-1-[(1,3,5-trimethyl-4-pyrazolyl)methyl]thiourea 0
                                          3-amino-N-(2-chlorophenyl)-4-(1-pyrrolidinyl)benzenesulfonamide 0
                                          3-benzoyl-1,5-bis(2-methoxyphenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione 0
                                          3-ethynyl-5-(1-methyl-2-pyrrolidinyl)pyridine 0
                                          3a-hydroxy-5-(2-methylbut-2-enylidene)-1-phenyl-3,6-dihydro-2H-pyrrolo[2,3-b]pyridin-4-one 0
                                          4,5-dioxo-2-phenyl-1-(4-sulfamoylphenyl)-3-pyrrolidinecarboxylic acid ethyl ester 0
                                          4-(1-benzofuran-2-carbonyl)-1-(5-methyl-1,2-oxazol-3-yl)-5-(3-prop-2-enoxyphenyl)pyrrolidine-2,3-dione 0
                                          4-(furan-2-carbonyl)-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(4-propan-2-ylphenyl)pyrrolidine-2,3-dione 0
                                          4-Chloro-2-(5-methyl-1,3-dioxooctahydro-2H-isoindol-2-yl)phenyl 2-furoate 0
                                          4-[(3S,6R,7S,8aS)-7-[[(4-fluorophenyl)methylamino]-oxomethyl]-6-[3-(2-hydroxyethoxy)phenyl]-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-3-yl]butyl-trimethylammonium 0
                                          4-[2-benzofuranyl(oxo)methyl]-1-[2-(4-morpholinyl)ethyl]-5-(3-pyridinyl)pyrrolidine-2,3-dione 0
                                          4-[3-(2,5-dimethyl-1-pyrrolyl)-4-(1-pyrrolidinyl)phenyl]sulfonylmorpholine 0
                                          4-[[[(2S,3R,5aS,10aS)-3-(4-hydroxyphenyl)-5,10-dioxo-1,2,3,5a,6,7,8,10a-octahydrodipyrrolo[1,2-c:1',3'-f]pyrazin-2-yl]-oxomethyl]amino]butyl-trimethylammonium 0
                                          4-[[[(3S,6R,7S,8aS)-3-(4-acetamidobutyl)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-7-yl]-oxomethyl]amino]butyl-trimethylammonium 0
                                          4-acetyl-1-[2-(1H-indol-3-yl)ethyl]-5-(3-methoxyphenyl)pyrrolidine-2,3-dione 0
                                          5'-Hydroxycotinine 0
                                          5-(2,4-dichlorophenyl)-4,6-dioxo-3a,6a-dihydro-2H-pyrrolo[3,4-d]isoxazole-3,3-dicarboxylic acid dimethyl ester 0
                                          5-(2-fluorophenyl)-4-(2-methyl-2,3-dihydro-1-benzofuran-5-carbonyl)-1-(2-morpholin-4-ylethyl)pyrrolidine-2,3-dione 0
                                          5-(3,4-dimethoxyphenyl)-4-(furan-2-carbonyl)-1-(2-phenylethyl)pyrrolidine-2,3-dione 0
                                          5-(3-bromophenyl)-1-(furan-2-ylmethyl)-4-(5-methylfuran-2-carbonyl)pyrrolidine-2,3-dione 0
                                          5-(3-butoxyphenyl)-1-(pyridin-3-ylmethyl)-4-(thiophene-2-carbonyl)pyrrolidine-2,3-dione 0
                                          5-(4-butoxyphenyl)-1-(furan-2-ylmethyl)-4-(5-methylfuran-2-carbonyl)pyrrolidine-2,3-dione 0
                                          5-(4-ethoxyphenyl)-1,3-diphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione 0
                                          5-Ethyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                                          5-Methyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                                          5-[[2,5-dimethoxy-4-(1-pyrrolidinyl)phenyl]methylidene]-3-methylthiazolidine-2,4-dione 0
                                          5-chloro-6-\{[(2Z)-2-iminopyrrolidin-1-yl]methyl\}uracil 0
                                          8-(4-hydroxy-3-methoxyphenyl)-6-(4-methylphenyl)-3,4a,7a,8-tetrahydropyrrolo[2,3]thiopyrano[4,5-b]thiazole-2,5,7-trione 0
                                          8-\{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl\}-5,7-dimethoxy-4-pentyl-2H-chromen-2-one 0
                                          Aganepag isopropyl 0
                                          Anhwiedelphinine 0
                                          BMS-754807 8
                                          Codonopsine 0
                                          FR901469 0
                                          LSM-16571 0
                                          LSM-18969 0
                                          LSM-26452 0
                                          LSM-26959 0
                                          LSM-27159 0
                                          LSM-27979 0
                                          LSM-28138 0
                                          LSM-28426 0
                                          LSM-28442 0
                                          LSM-32103 0
                                          LSM-32133 0
                                          LSM-32492 0
                                          Lansimide 3 0
                                          MI-63 0
                                          Maltoxazine 0
                                          Mesembrenone 0
                                          Mesembrine 0
                                          Mesembrinol 0
                                          N'-Hydroxymethylnorcotinine 0
                                          N'-Nitrosonornicotine 13
                                          N'-[(3-bromo-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-2-(2-oxo-4-phenyl-1-pyrrolidinyl)acetohydrazide 0
                                          N,3-diphenyl-1-pyrrolidinecarboxamide 0
                                          N,N'-diphenylcarbamimidothioic acid [1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl] ester 0
                                          N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide 0
                                          N,N-dipropyl-2-(pyrrolidin-1-yl)quinazolin-4-amine 0
                                          N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine + 0
                                          N-(2,4-dinitrophenyl)-L-proline 0
                                          N-(2,4-dinitrophenyl)proline 0
                                          N-(3,5-Dichlorophenyl)succinimide 1
                                          N-(4-methyl-2-pyridinyl)-2-[3-(trifluoromethyl)phenyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carbothioamide 0
                                          N-(\{(2S,4R)-4-[(4-chlorobenzyl)oxy]pyrrolidin-2-yl\}methyl)isoquinoline-5-sulfonamide 0
                                          N-Methylnicotinium 0
                                          N-Nitrosopyrrolidine 796
                                          N-[(1,5-dimethyl-2-pyrrolyl)methyl]-1-(4-methylphenyl)-5-oxo-3-pyrrolidinecarboxamide 0
                                          N-[3-[2,5-dioxo-3-(phenylmethyl)-1-pyrrolidinyl]phenyl]acetamide 0
                                          N-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzenesulfonamide 0
                                          N-acylpyrrolidine + 47
                                          N-alkylpyrrolidine + 1182
                                          N-benzyl-2-(2,6-dimethylphenoxy)-N-[((3R,4S)-4-\{[isobutyl(phenylsulfonyl)amino]methyl\}pyrrolidin-3-yl)methyl]acetamide 0
                                          N-butyl-N-[2,5-dioxo-1-(4-propoxyphenyl)-3-pyrrolidinyl]acetamide 0
                                          Norcotinine 0
                                          Phensuximide 0
                                          SLM6071469 0
                                          allyl \{(1S)-1-[(5-\{4-[(2,3-dihydro-1H-inden-2-ylamino)carbonyl]benzyl\}-1,2,4-oxadiazol-3-yl)carbonyl]-3-pyrrolidin-3-ylpropyl\}carbamate 0
                                          aminopyrrolidine + 0
                                          amisulpride 3
                                          atrasentan 13
                                          bepridil + 9
                                          beta-Homoproline 0
                                          clemizole 11
                                          darifenacin + 3
                                          epolamine 0
                                          eribaxaban 0
                                          ficellomycin 0
                                          fluoropyrrolidine + 0
                                          flurochloridone 0
                                          hydroxypyrrolidine + 91
                                          methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate 0
                                          methyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate 0
                                          methyl 5-(hydroxymethyl)pyrrolidine-2-carboxylate 0
                                          methyl 5-(hydroxymethyl)pyrrolidine-3-carboxylate 0
                                          miboplatin 0
                                          nafadotride 3
                                          nicotine bitartrate 0
                                          ombitasvir + 0
                                          phyllospadine 0
                                          picilorex 0
                                          piromidic acid 0
                                          procyclidine + 13
                                          proline + 273
                                          prolinols + 0
                                          pyrrolidin-2-ylmethylamine + 0
                                          pyrrolidine + 2
                                          pyrrolidine N-oxides + 0
                                          pyrrolidine alkaloid + 1119
                                          pyrrolidine dithiocarbamate 207
                                          pyrrolidinecarbaldehyde + 0
                                          pyrrolidinecarbohydrazide + 0
                                          pyrrolidinecarbonitrile + 0
                                          pyrrolidinecarboxamide + 32
                                          pyrrolidinecarboxylic acid + 238
                                          pyrrolidinehydroxamic acid + 0
                                          pyrrolidinesulfonic acid + 0
                                          pyrrolidinone + 166
                                          pyrrolidinoquinazoline + 0
                                          rolicyclidine 0
                                          suclofenide 0
                                          tipiracil 0
                                          trans-4,5-Dimethyl-2-(1-pyrrolidinyl)-2-cyclopenten-1-one 0
                                          vibegron 0
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