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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:pyrrolidines
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Accession:CHEBI:38260 term browser browse the term
Definition:Any of a class of heterocyclic amines having a saturated five-membered ring.
Synonyms:alt_id: CHEBI:26922;   CHEBI:38191;   MESH:D011759
 xref_mesh: MESH:D011759


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  CHEBI ontology 19787
    chemical entity 19787
      atom 19784
        nonmetal atom 19659
          nitrogen atom 18542
            nitrogen molecular entity 18542
              organonitrogen compound 18312
                organonitrogen heterocyclic compound 17461
                  pyrrolidines 2223
                    (+)-Nornicotine 0
                    (2R,3R)-1-(2,3-dihydro-1H-inden-2-yl)-2-[4-(hydroxymethyl)-2-iodophenyl]-3-[(4-methylphenyl)thio]-5-oxo-N-propan-2-yl-3-pyrrolidinecarboxamide 0
                    (2R,3R)-1-(2,3-dihydro-1H-inden-2-yl)-2-[4-(hydroxymethyl)-2-iodophenyl]-3-[(4-methylphenyl)thio]-N-[2-(4-morpholinyl)ethyl]-5-oxo-3-pyrrolidinecarboxamide 0
                    (3R)-3-(2-fluoro-5-methylphenyl)-7-phenyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                    (3R)-7-phenyl-2-(phenylmethyl)-3-[4-(trifluoromethyl)phenyl]-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                    (3R,3aS,7R,7aS)-3-[5-(1-benzothiophen-2-yl)-2-methoxyphenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                    (3R,3aS,7R,7aS)-7-methyl-3-(2-naphthalenyl)-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                    (3S,6S,7R,8aR)-6-(4-hydroxyphenyl)-N-[5-[(2-mercapto-1-oxoethyl)amino]pentyl]-3-(2-methylpropyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                    (3S,6S,7R,8aR)-6-[3-(2-hydroxyethoxy)phenyl]-N-[5-[(2-mercapto-1-oxoethyl)amino]pentyl]-3-(2-methylpropyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                    (3aR,6aR)-5-(3-methoxyphenyl)-3-[oxo(2-pyrazinyl)methyl]-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione 0
                    (3aR,6aS)-3-(2-chlorophenyl)-5-(2,5-dimethoxyphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione 0
                    (3aR,6aS)-3-(3,4-dimethoxyphenyl)-5-(2,4-dimethylphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione 0
                    (5-tert-butyl-1,3,4-oxadiazol-2-yl)[(2R)-pyrrolidin-2-yl]methanone 0
                    (6R,7S,8aS)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxylic acid 0
                    (6R,7S,8aS)-N-(5-aminopentyl)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                    (6S,7R,8aR)-N-[6-(dimethylamino)hexyl]-6-[3-(2-hydroxyethoxy)phenyl]-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                    (S)-2-(methoxymethyl)pyrrolidine 0
                    1-(1-pyrrolidinyl)-1-octadecanone 0
                    1-(2,4-dinitroanilino)-3-(4-propan-2-yloxyphenyl)pyrrolidine-2,5-dione 0
                    1-(2,6-dimethylphenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]thiourea 0
                    1-(2-furanylmethyl)-4-[oxo(thiophen-2-yl)methyl]-5-phenylpyrrolidine-2,3-dione 0
                    1-(2-hydroxyethyl)pyrrolidinium + 0
                    1-(3,4-dimethylphenyl)-3-(2-pyrimidinylthio)pyrrolidine-2,5-dione 0
                    1-(3,5-dichlorophenyl)-3-(4-morpholinyl)pyrrolidine-2,5-dione 0
                    1-(3,5-dichlorophenyl)-3-(N-hydroxyanilino)pyrrolidine-2,5-dione 0
                    1-(3,5-dimethylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione 0
                    1-(3,5-dimethylphenyl)-4-(1-ethyl-2-benzimidazolyl)-2-pyrrolidinone 0
                    1-(3-chloro-4-fluorophenyl)-4-[(4-methyl-1-piperazinyl)-oxomethyl]-2-pyrrolidinone 0
                    1-(3-chloro-4-methylphenyl)-5-oxo-N-(2-thiazolyl)-3-pyrrolidinecarboxamide 0
                    1-(4-bromophenyl)-3-(diethylamino)pyrrolidine-2,5-dione 0
                    1-(4-bromophenyl)-N-(3,4-dichlorophenyl)-5-oxo-3-pyrrolidinecarboxamide 0
                    1-(4-chlorophenyl)-2-[5-(1-pyrrolidinyl)-2-tetrazolyl]ethanone oxime 0
                    1-(4-chlorophenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]urea 0
                    1-(4-ethoxyphenyl)-3-[(1,3,3-trimethyl-2-indolylidene)methyl]pyrrolidine-2,5-dione 0
                    1-(4-ethoxyphenyl)-3-[methyl-(phenylmethyl)amino]pyrrolidine-2,5-dione 0
                    1-(4-methoxyphenyl)-3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)pyrrolidine-2,5-dione 0
                    1-(4-methoxyphenyl)-N'-[(3-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-5-oxo-3-pyrrolidinecarbohydrazide 0
                    1-(4-methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide 0
                    1-(4-methylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione 0
                    1-(4-nitrophenyl)-3-[(1,3,3-trimethyl-2-indolylidene)methyl]pyrrolidine-2,5-dione 0
                    1-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-(5-pyrrolidin-2-yl-1H-pyrazol-3-yl)urea 0
                    1-[1-(3-chloro-4-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-4-piperidinecarboxamide 0
                    1-[1-(3-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-4-piperidinecarboxamide 0
                    1-[4-[2-(2-propan-2-ylidenehydrazinyl)-4-thiazolyl]phenyl]pyrrolidine-2,5-dione 0
                    1-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(2,4,6-trimethylphenyl)thiourea 0
                    2,2-dimethyl-3-(4-methoxyphenyl)-4-ethyl-6-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol 0
                    2,2-dimethyl-3-(4-methoxyphenyl)-4-ethyl-8-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol 0
                    2-(3-nitrophenyl)-4,5-dioxo-1-phenyl-3-pyrrolidinecarboxylic acid ethyl ester 0
                    2-(4-methoxyphenyl)-4,5-dioxo-1-(4-sulfamoylphenyl)-3-pyrrolidinecarboxylic acid ethyl ester 0
                    2-(pyridin-4-yl)-4-(pyrrolidin-1-yl)quinazoline 0
                    2-[4-(cyclohexylamino)-3-nitrophenyl]-5-methyl-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione 0
                    2-[4-[2-(4-chlorophenyl)ethylamino]-3-nitrophenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-dione 0
                    2-[7-oxo-7-(3-phenyl-1-pyrrolidinyl)heptyl]isoindole-1,3-dione 0
                    2-[[1-(4-ethoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]amino]acetonitrile 0
                    2-[[1-(4-methoxy-2-nitrophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]benzoic acid 0
                    2-methylpyrrolidine + 1
                    3',4'-difluoro-N-\{4'-fluoro-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-yl\}-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-carboxamide 0
                    3-(1,3-benzothiazol-2-ylhydrazo)-1-(4-ethylphenyl)pyrrolidine-2,5-dione 0
                    3-(1-ethyl-2-pyrrolidinyl)pyridine 0
                    3-(1H-indol-3-yl)-1-phenylpyrrolidine-2,5-dione 0
                    3-(2-pyrimidinylthio)-1-[2-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione 0
                    3-(4-methylphenyl)-N-phenyl-1-pyrrolidinecarboxamide 0
                    3-[(1-methyl-5-tetrazolyl)thio]-1-phenylpyrrolidine-2,5-dione 0
                    3-[1-(2,4-dichlorophenyl)sulfonyl-2-pyrrolidinyl]pyridine 0
                    3-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-phenylpyrrolidine-2,5-dione 0
                    3-[4-(dimethylamino)phenyl]-1-[1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl]-1-[(1,3,5-trimethyl-4-pyrazolyl)methyl]thiourea 0
                    3-amino-N-(2-chlorophenyl)-4-(1-pyrrolidinyl)benzenesulfonamide 0
                    3-benzoyl-1,5-bis(2-methoxyphenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione 0
                    3-ethynyl-5-(1-methyl-2-pyrrolidinyl)pyridine 0
                    3a-hydroxy-5-(2-methylbut-2-enylidene)-1-phenyl-3,6-dihydro-2H-pyrrolo[2,3-b]pyridin-4-one 0
                    4,5-dioxo-2-phenyl-1-(4-sulfamoylphenyl)-3-pyrrolidinecarboxylic acid ethyl ester 0
                    4-(1-benzofuran-2-carbonyl)-1-(5-methyl-1,2-oxazol-3-yl)-5-(3-prop-2-enoxyphenyl)pyrrolidine-2,3-dione 0
                    4-(furan-2-carbonyl)-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(4-propan-2-ylphenyl)pyrrolidine-2,3-dione 0
                    4-Chloro-2-(5-methyl-1,3-dioxooctahydro-2H-isoindol-2-yl)phenyl 2-furoate 0
                    4-[(3S,6R,7S,8aS)-7-[[(4-fluorophenyl)methylamino]-oxomethyl]-6-[3-(2-hydroxyethoxy)phenyl]-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-3-yl]butyl-trimethylammonium 0
                    4-[2-benzofuranyl(oxo)methyl]-1-[2-(4-morpholinyl)ethyl]-5-(3-pyridinyl)pyrrolidine-2,3-dione 0
                    4-[3-(2,5-dimethyl-1-pyrrolyl)-4-(1-pyrrolidinyl)phenyl]sulfonylmorpholine 0
                    4-[[[(2S,3R,5aS,10aS)-3-(4-hydroxyphenyl)-5,10-dioxo-1,2,3,5a,6,7,8,10a-octahydrodipyrrolo[1,2-c:1',3'-f]pyrazin-2-yl]-oxomethyl]amino]butyl-trimethylammonium 0
                    4-[[[(3S,6R,7S,8aS)-3-(4-acetamidobutyl)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-7-yl]-oxomethyl]amino]butyl-trimethylammonium 0
                    4-acetyl-1-[2-(1H-indol-3-yl)ethyl]-5-(3-methoxyphenyl)pyrrolidine-2,3-dione 0
                    5-(2,4-dichlorophenyl)-4,6-dioxo-3a,6a-dihydro-2H-pyrrolo[3,4-d]isoxazole-3,3-dicarboxylic acid dimethyl ester 0
                    5-(2-fluorophenyl)-4-(2-methyl-2,3-dihydro-1-benzofuran-5-carbonyl)-1-(2-morpholin-4-ylethyl)pyrrolidine-2,3-dione 0
                    5-(3,4-dimethoxyphenyl)-4-(furan-2-carbonyl)-1-(2-phenylethyl)pyrrolidine-2,3-dione 0
                    5-(3-bromophenyl)-1-(furan-2-ylmethyl)-4-(5-methylfuran-2-carbonyl)pyrrolidine-2,3-dione 0
                    5-(3-butoxyphenyl)-1-(pyridin-3-ylmethyl)-4-(thiophene-2-carbonyl)pyrrolidine-2,3-dione 0
                    5-(4-butoxyphenyl)-1-(furan-2-ylmethyl)-4-(5-methylfuran-2-carbonyl)pyrrolidine-2,3-dione 0
                    5-(4-ethoxyphenyl)-1,3-diphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione 0
                    5-[[2,5-dimethoxy-4-(1-pyrrolidinyl)phenyl]methylidene]-3-methylthiazolidine-2,4-dione 0
                    5-chloro-6-\{[(2Z)-2-iminopyrrolidin-1-yl]methyl\}uracil 0
                    8-(4-hydroxy-3-methoxyphenyl)-6-(4-methylphenyl)-3,4a,7a,8-tetrahydropyrrolo[2,3]thiopyrano[4,5-b]thiazole-2,5,7-trione 0
                    8-\{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl\}-5,7-dimethoxy-4-pentyl-2H-chromen-2-one 0
                    Anhwiedelphinine 0
                    BMS-754807 8
                    Codonopsine 0
                    FR901469 0
                    LSM-16571 0
                    LSM-18969 0
                    LSM-26452 0
                    LSM-26959 0
                    LSM-27159 0
                    LSM-27979 0
                    LSM-28138 0
                    LSM-28426 0
                    LSM-28442 0
                    LSM-32103 0
                    LSM-32133 0
                    LSM-32492 0
                    MI-63 0
                    Mesembrenone 0
                    Mesembrine 0
                    Mesembrinol 0
                    N'-Nitrosonornicotine 13
                    N'-[(3-bromo-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-2-(2-oxo-4-phenyl-1-pyrrolidinyl)acetohydrazide 0
                    N,3-diphenyl-1-pyrrolidinecarboxamide 0
                    N,N'-diphenylcarbamimidothioic acid [1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl] ester 0
                    N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide 0
                    N,N-dipropyl-2-(pyrrolidin-1-yl)quinazolin-4-amine 0
                    N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine + 0
                    N-(2,4-dinitrophenyl)-L-proline 0
                    N-(2,4-dinitrophenyl)proline 0
                    N-(3,5-Dichlorophenyl)succinimide 1
                    N-(4-methyl-2-pyridinyl)-2-[3-(trifluoromethyl)phenyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carbothioamide 0
                    N-(\{(2S,4R)-4-[(4-chlorobenzyl)oxy]pyrrolidin-2-yl\}methyl)isoquinoline-5-sulfonamide 0
                    N-Nitrosopyrrolidine 797
                    N-[(1,5-dimethyl-2-pyrrolyl)methyl]-1-(4-methylphenyl)-5-oxo-3-pyrrolidinecarboxamide 0
                    N-[3-[2,5-dioxo-3-(phenylmethyl)-1-pyrrolidinyl]phenyl]acetamide 0
                    N-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzenesulfonamide 0
                    N-acylpyrrolidine + 41
                    N-alkylpyrrolidine + 1133
                    N-benzyl-2-(2,6-dimethylphenoxy)-N-[((3R,4S)-4-\{[isobutyl(phenylsulfonyl)amino]methyl\}pyrrolidin-3-yl)methyl]acetamide 0
                    N-butyl-N-[2,5-dioxo-1-(4-propoxyphenyl)-3-pyrrolidinyl]acetamide 0
                    Norcotinine 0
                    Phensuximide 0
                    allyl \{(1S)-1-[(5-\{4-[(2,3-dihydro-1H-inden-2-ylamino)carbonyl]benzyl\}-1,2,4-oxadiazol-3-yl)carbonyl]-3-pyrrolidin-3-ylpropyl\}carbamate 0
                    aminopyrrolidine + 0
                    amisulpride 3
                    atrasentan 13
                    bepridil + 8
                    clemizole 10
                    darifenacin + 3
                    epolamine 0
                    eribaxaban 0
                    ficellomycin 0
                    fluoropyrrolidine + 0
                    flurochloridone 0
                    hydroxypyrrolidine + 87
                    methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate 0
                    methyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate 0
                    methyl 5-(hydroxymethyl)pyrrolidine-2-carboxylate 0
                    methyl 5-(hydroxymethyl)pyrrolidine-3-carboxylate 0
                    miboplatin 0
                    nafadotride 3
                    nicotine bitartrate 0
                    ombitasvir + 0
                    phyllospadine 0
                    picilorex 0
                    piromidic acid 0
                    procyclidine + 2
                    proline + 269
                    prolinols + 0
                    pyrrolidin-2-ylmethylamine + 0
                    pyrrolidine + 2
                    pyrrolidine N-oxides + 0
                    pyrrolidine alkaloid + 1090
                    pyrrolidine dithiocarbamate 206
                    pyrrolidinecarbaldehyde + 0
                    pyrrolidinecarbohydrazide + 0
                    pyrrolidinecarbonitrile + 0
                    pyrrolidinecarboxamide + 6
                    pyrrolidinecarboxylic acid + 235
                    pyrrolidinehydroxamic acid + 0
                    pyrrolidinesulfonic acid + 0
                    pyrrolidinone + 165
                    pyrrolidinoquinazoline + 0
                    rolicyclidine 0
                    suclofenide 0
                    tipiracil 0
                    vibegron 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19488
                              organic cyclic compound 19285
                                organic heterocyclic compound 18410
                                  organic heteromonocyclic compound 16445
                                    pyrrolidines 2223
                                      (+)-Nornicotine 0
                                      (2R,3R)-1-(2,3-dihydro-1H-inden-2-yl)-2-[4-(hydroxymethyl)-2-iodophenyl]-3-[(4-methylphenyl)thio]-5-oxo-N-propan-2-yl-3-pyrrolidinecarboxamide 0
                                      (2R,3R)-1-(2,3-dihydro-1H-inden-2-yl)-2-[4-(hydroxymethyl)-2-iodophenyl]-3-[(4-methylphenyl)thio]-N-[2-(4-morpholinyl)ethyl]-5-oxo-3-pyrrolidinecarboxamide 0
                                      (3R)-3-(2-fluoro-5-methylphenyl)-7-phenyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                                      (3R)-7-phenyl-2-(phenylmethyl)-3-[4-(trifluoromethyl)phenyl]-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                                      (3R,3aS,7R,7aS)-3-[5-(1-benzothiophen-2-yl)-2-methoxyphenyl]-7-methyl-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                                      (3R,3aS,7R,7aS)-7-methyl-3-(2-naphthalenyl)-2-(phenylmethyl)-3a,6,7,7a-tetrahydro-3H-isoindol-1-one 0
                                      (3S,6S,7R,8aR)-6-(4-hydroxyphenyl)-N-[5-[(2-mercapto-1-oxoethyl)amino]pentyl]-3-(2-methylpropyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                                      (3S,6S,7R,8aR)-6-[3-(2-hydroxyethoxy)phenyl]-N-[5-[(2-mercapto-1-oxoethyl)amino]pentyl]-3-(2-methylpropyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                                      (3aR,6aR)-5-(3-methoxyphenyl)-3-[oxo(2-pyrazinyl)methyl]-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione 0
                                      (3aR,6aS)-3-(2-chlorophenyl)-5-(2,5-dimethoxyphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione 0
                                      (3aR,6aS)-3-(3,4-dimethoxyphenyl)-5-(2,4-dimethylphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione 0
                                      (5-tert-butyl-1,3,4-oxadiazol-2-yl)[(2R)-pyrrolidin-2-yl]methanone 0
                                      (6R,7S,8aS)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxylic acid 0
                                      (6R,7S,8aS)-N-(5-aminopentyl)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                                      (6S,7R,8aR)-N-[6-(dimethylamino)hexyl]-6-[3-(2-hydroxyethoxy)phenyl]-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-7-carboxamide 0
                                      (S)-2-(methoxymethyl)pyrrolidine 0
                                      1-(1-pyrrolidinyl)-1-octadecanone 0
                                      1-(2,4-dinitroanilino)-3-(4-propan-2-yloxyphenyl)pyrrolidine-2,5-dione 0
                                      1-(2,6-dimethylphenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]thiourea 0
                                      1-(2-furanylmethyl)-4-[oxo(thiophen-2-yl)methyl]-5-phenylpyrrolidine-2,3-dione 0
                                      1-(2-hydroxyethyl)pyrrolidinium + 0
                                      1-(3,4-dimethylphenyl)-3-(2-pyrimidinylthio)pyrrolidine-2,5-dione 0
                                      1-(3,5-dichlorophenyl)-3-(4-morpholinyl)pyrrolidine-2,5-dione 0
                                      1-(3,5-dichlorophenyl)-3-(N-hydroxyanilino)pyrrolidine-2,5-dione 0
                                      1-(3,5-dimethylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione 0
                                      1-(3,5-dimethylphenyl)-4-(1-ethyl-2-benzimidazolyl)-2-pyrrolidinone 0
                                      1-(3-chloro-4-fluorophenyl)-4-[(4-methyl-1-piperazinyl)-oxomethyl]-2-pyrrolidinone 0
                                      1-(3-chloro-4-methylphenyl)-5-oxo-N-(2-thiazolyl)-3-pyrrolidinecarboxamide 0
                                      1-(4-bromophenyl)-3-(diethylamino)pyrrolidine-2,5-dione 0
                                      1-(4-bromophenyl)-N-(3,4-dichlorophenyl)-5-oxo-3-pyrrolidinecarboxamide 0
                                      1-(4-chlorophenyl)-2-[5-(1-pyrrolidinyl)-2-tetrazolyl]ethanone oxime 0
                                      1-(4-chlorophenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]urea 0
                                      1-(4-ethoxyphenyl)-3-[(1,3,3-trimethyl-2-indolylidene)methyl]pyrrolidine-2,5-dione 0
                                      1-(4-ethoxyphenyl)-3-[methyl-(phenylmethyl)amino]pyrrolidine-2,5-dione 0
                                      1-(4-methoxyphenyl)-3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)pyrrolidine-2,5-dione 0
                                      1-(4-methoxyphenyl)-N'-[(3-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-5-oxo-3-pyrrolidinecarbohydrazide 0
                                      1-(4-methoxyphenyl)-N-(4-methyl-2-pyridinyl)-5-oxo-3-pyrrolidinecarboxamide 0
                                      1-(4-methylphenyl)-3-(1H-1,2,4-triazol-5-ylthio)pyrrolidine-2,5-dione 0
                                      1-(4-nitrophenyl)-3-[(1,3,3-trimethyl-2-indolylidene)methyl]pyrrolidine-2,5-dione 0
                                      1-(5-oxo-2,3,5,9b-tetrahydro-1H-pyrrolo[2,1-a]isoindol-9-yl)-3-(5-pyrrolidin-2-yl-1H-pyrazol-3-yl)urea 0
                                      1-[1-(3-chloro-4-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-4-piperidinecarboxamide 0
                                      1-[1-(3-fluorophenyl)-2,5-dioxo-3-pyrrolidinyl]-4-piperidinecarboxamide 0
                                      1-[4-[2-(2-propan-2-ylidenehydrazinyl)-4-thiazolyl]phenyl]pyrrolidine-2,5-dione 0
                                      1-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(2,4,6-trimethylphenyl)thiourea 0
                                      2,2-dimethyl-3-(4-methoxyphenyl)-4-ethyl-6-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol 0
                                      2,2-dimethyl-3-(4-methoxyphenyl)-4-ethyl-8-(1-pyrrolidinylmethyl)-2H-1-benzopyran-7-ol 0
                                      2-(3-nitrophenyl)-4,5-dioxo-1-phenyl-3-pyrrolidinecarboxylic acid ethyl ester 0
                                      2-(4-methoxyphenyl)-4,5-dioxo-1-(4-sulfamoylphenyl)-3-pyrrolidinecarboxylic acid ethyl ester 0
                                      2-(pyridin-4-yl)-4-(pyrrolidin-1-yl)quinazoline 0
                                      2-[4-(cyclohexylamino)-3-nitrophenyl]-5-methyl-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione 0
                                      2-[4-[2-(4-chlorophenyl)ethylamino]-3-nitrophenyl]-3a,4,7,7a-tetrahydroisoindole-1,3-dione 0
                                      2-[7-oxo-7-(3-phenyl-1-pyrrolidinyl)heptyl]isoindole-1,3-dione 0
                                      2-[[1-(4-ethoxyphenyl)-2,5-dioxo-3-pyrrolidinyl]amino]acetonitrile 0
                                      2-[[1-(4-methoxy-2-nitrophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]benzoic acid 0
                                      2-methylpyrrolidine + 1
                                      3',4'-difluoro-N-\{4'-fluoro-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-yl\}-6-[(3S)-pyrrolidin-3-yloxy][biphenyl]-3-carboxamide 0
                                      3-(1,3-benzothiazol-2-ylhydrazo)-1-(4-ethylphenyl)pyrrolidine-2,5-dione 0
                                      3-(1-ethyl-2-pyrrolidinyl)pyridine 0
                                      3-(1H-indol-3-yl)-1-phenylpyrrolidine-2,5-dione 0
                                      3-(2-pyrimidinylthio)-1-[2-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione 0
                                      3-(4-methylphenyl)-N-phenyl-1-pyrrolidinecarboxamide 0
                                      3-[(1-methyl-5-tetrazolyl)thio]-1-phenylpyrrolidine-2,5-dione 0
                                      3-[1-(2,4-dichlorophenyl)sulfonyl-2-pyrrolidinyl]pyridine 0
                                      3-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-phenylpyrrolidine-2,5-dione 0
                                      3-[4-(dimethylamino)phenyl]-1-[1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl]-1-[(1,3,5-trimethyl-4-pyrazolyl)methyl]thiourea 0
                                      3-amino-N-(2-chlorophenyl)-4-(1-pyrrolidinyl)benzenesulfonamide 0
                                      3-benzoyl-1,5-bis(2-methoxyphenyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione 0
                                      3-ethynyl-5-(1-methyl-2-pyrrolidinyl)pyridine 0
                                      3a-hydroxy-5-(2-methylbut-2-enylidene)-1-phenyl-3,6-dihydro-2H-pyrrolo[2,3-b]pyridin-4-one 0
                                      4,5-dioxo-2-phenyl-1-(4-sulfamoylphenyl)-3-pyrrolidinecarboxylic acid ethyl ester 0
                                      4-(1-benzofuran-2-carbonyl)-1-(5-methyl-1,2-oxazol-3-yl)-5-(3-prop-2-enoxyphenyl)pyrrolidine-2,3-dione 0
                                      4-(furan-2-carbonyl)-1-(5-methyl-1,3,4-thiadiazol-2-yl)-5-(4-propan-2-ylphenyl)pyrrolidine-2,3-dione 0
                                      4-Chloro-2-(5-methyl-1,3-dioxooctahydro-2H-isoindol-2-yl)phenyl 2-furoate 0
                                      4-[(3S,6R,7S,8aS)-7-[[(4-fluorophenyl)methylamino]-oxomethyl]-6-[3-(2-hydroxyethoxy)phenyl]-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-3-yl]butyl-trimethylammonium 0
                                      4-[2-benzofuranyl(oxo)methyl]-1-[2-(4-morpholinyl)ethyl]-5-(3-pyridinyl)pyrrolidine-2,3-dione 0
                                      4-[3-(2,5-dimethyl-1-pyrrolyl)-4-(1-pyrrolidinyl)phenyl]sulfonylmorpholine 0
                                      4-[[[(2S,3R,5aS,10aS)-3-(4-hydroxyphenyl)-5,10-dioxo-1,2,3,5a,6,7,8,10a-octahydrodipyrrolo[1,2-c:1',3'-f]pyrazin-2-yl]-oxomethyl]amino]butyl-trimethylammonium 0
                                      4-[[[(3S,6R,7S,8aS)-3-(4-acetamidobutyl)-6-(4-hydroxyphenyl)-1,4-dioxo-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazin-7-yl]-oxomethyl]amino]butyl-trimethylammonium 0
                                      4-acetyl-1-[2-(1H-indol-3-yl)ethyl]-5-(3-methoxyphenyl)pyrrolidine-2,3-dione 0
                                      5-(2,4-dichlorophenyl)-4,6-dioxo-3a,6a-dihydro-2H-pyrrolo[3,4-d]isoxazole-3,3-dicarboxylic acid dimethyl ester 0
                                      5-(2-fluorophenyl)-4-(2-methyl-2,3-dihydro-1-benzofuran-5-carbonyl)-1-(2-morpholin-4-ylethyl)pyrrolidine-2,3-dione 0
                                      5-(3,4-dimethoxyphenyl)-4-(furan-2-carbonyl)-1-(2-phenylethyl)pyrrolidine-2,3-dione 0
                                      5-(3-bromophenyl)-1-(furan-2-ylmethyl)-4-(5-methylfuran-2-carbonyl)pyrrolidine-2,3-dione 0
                                      5-(3-butoxyphenyl)-1-(pyridin-3-ylmethyl)-4-(thiophene-2-carbonyl)pyrrolidine-2,3-dione 0
                                      5-(4-butoxyphenyl)-1-(furan-2-ylmethyl)-4-(5-methylfuran-2-carbonyl)pyrrolidine-2,3-dione 0
                                      5-(4-ethoxyphenyl)-1,3-diphenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione 0
                                      5-[[2,5-dimethoxy-4-(1-pyrrolidinyl)phenyl]methylidene]-3-methylthiazolidine-2,4-dione 0
                                      5-chloro-6-\{[(2Z)-2-iminopyrrolidin-1-yl]methyl\}uracil 0
                                      8-(4-hydroxy-3-methoxyphenyl)-6-(4-methylphenyl)-3,4a,7a,8-tetrahydropyrrolo[2,3]thiopyrano[4,5-b]thiazole-2,5,7-trione 0
                                      8-\{1-[4-(dimethylamino)phenyl]-3-(pyrrolidin-1-yl)propyl\}-5,7-dimethoxy-4-pentyl-2H-chromen-2-one 0
                                      Anhwiedelphinine 0
                                      BMS-754807 8
                                      Codonopsine 0
                                      FR901469 0
                                      LSM-16571 0
                                      LSM-18969 0
                                      LSM-26452 0
                                      LSM-26959 0
                                      LSM-27159 0
                                      LSM-27979 0
                                      LSM-28138 0
                                      LSM-28426 0
                                      LSM-28442 0
                                      LSM-32103 0
                                      LSM-32133 0
                                      LSM-32492 0
                                      MI-63 0
                                      Mesembrenone 0
                                      Mesembrine 0
                                      Mesembrinol 0
                                      N'-Nitrosonornicotine 13
                                      N'-[(3-bromo-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-2-(2-oxo-4-phenyl-1-pyrrolidinyl)acetohydrazide 0
                                      N,3-diphenyl-1-pyrrolidinecarboxamide 0
                                      N,N'-diphenylcarbamimidothioic acid [1-(3-methylphenyl)-2,5-dioxo-3-pyrrolidinyl] ester 0
                                      N,N-diethyl-3-[(4-fluorophenyl)sulfonylamino]-4-(1-pyrrolidinyl)benzenesulfonamide 0
                                      N,N-dipropyl-2-(pyrrolidin-1-yl)quinazolin-4-amine 0
                                      N-(1-benzylpyrrolidin-3-yl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine + 0
                                      N-(2,4-dinitrophenyl)-L-proline 0
                                      N-(2,4-dinitrophenyl)proline 0
                                      N-(3,5-Dichlorophenyl)succinimide 1
                                      N-(4-methyl-2-pyridinyl)-2-[3-(trifluoromethyl)phenyl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carbothioamide 0
                                      N-(\{(2S,4R)-4-[(4-chlorobenzyl)oxy]pyrrolidin-2-yl\}methyl)isoquinoline-5-sulfonamide 0
                                      N-Nitrosopyrrolidine 797
                                      N-[(1,5-dimethyl-2-pyrrolyl)methyl]-1-(4-methylphenyl)-5-oxo-3-pyrrolidinecarboxamide 0
                                      N-[3-[2,5-dioxo-3-(phenylmethyl)-1-pyrrolidinyl]phenyl]acetamide 0
                                      N-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]-3-(trifluoromethyl)benzenesulfonamide 0
                                      N-acylpyrrolidine + 41
                                      N-alkylpyrrolidine + 1133
                                      N-benzyl-2-(2,6-dimethylphenoxy)-N-[((3R,4S)-4-\{[isobutyl(phenylsulfonyl)amino]methyl\}pyrrolidin-3-yl)methyl]acetamide 0
                                      N-butyl-N-[2,5-dioxo-1-(4-propoxyphenyl)-3-pyrrolidinyl]acetamide 0
                                      Norcotinine 0
                                      Phensuximide 0
                                      allyl \{(1S)-1-[(5-\{4-[(2,3-dihydro-1H-inden-2-ylamino)carbonyl]benzyl\}-1,2,4-oxadiazol-3-yl)carbonyl]-3-pyrrolidin-3-ylpropyl\}carbamate 0
                                      aminopyrrolidine + 0
                                      amisulpride 3
                                      atrasentan 13
                                      bepridil + 8
                                      clemizole 10
                                      darifenacin + 3
                                      epolamine 0
                                      eribaxaban 0
                                      ficellomycin 0
                                      fluoropyrrolidine + 0
                                      flurochloridone 0
                                      hydroxypyrrolidine + 87
                                      methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate 0
                                      methyl 3-(hydroxymethyl)pyrrolidine-1-carboxylate 0
                                      methyl 5-(hydroxymethyl)pyrrolidine-2-carboxylate 0
                                      methyl 5-(hydroxymethyl)pyrrolidine-3-carboxylate 0
                                      miboplatin 0
                                      nafadotride 3
                                      nicotine bitartrate 0
                                      ombitasvir + 0
                                      phyllospadine 0
                                      picilorex 0
                                      piromidic acid 0
                                      procyclidine + 2
                                      proline + 269
                                      prolinols + 0
                                      pyrrolidin-2-ylmethylamine + 0
                                      pyrrolidine + 2
                                      pyrrolidine N-oxides + 0
                                      pyrrolidine alkaloid + 1090
                                      pyrrolidine dithiocarbamate 206
                                      pyrrolidinecarbaldehyde + 0
                                      pyrrolidinecarbohydrazide + 0
                                      pyrrolidinecarbonitrile + 0
                                      pyrrolidinecarboxamide + 6
                                      pyrrolidinecarboxylic acid + 235
                                      pyrrolidinehydroxamic acid + 0
                                      pyrrolidinesulfonic acid + 0
                                      pyrrolidinone + 165
                                      pyrrolidinoquinazoline + 0
                                      rolicyclidine 0
                                      suclofenide 0
                                      tipiracil 0
                                      vibegron 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.