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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:DNA polymerase inhibitor
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Accession:CHEBI:38234 term browser browse the term
Definition:Any inhibitor of a DNA polymerase.



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aphidicolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein]; [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased expression of BSCL2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin multiple interactions
increases expression
ISO [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased expression of BSCL2 mRNA] CTD PMID:22003191 NCBI chr 1:215,160,764...215,172,540
Ensembl chr 1:215,160,957...215,172,536
JBrowse link
G Ccna2 cyclin A2 increases expression ISO Aphidicolin results in increased expression of CCNA2 mRNA CTD PMID:14738865 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein] CTD PMID:22003191 NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]]
[7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]
CTD PMID:18158334 PMID:22003191 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:51,449,140...51,480,667
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Aphidicolin results in increased expression of CYP26A1 mRNA CTD PMID:29990529 NCBI chr 1:244,883,822...244,887,657
Ensembl chr 1:244,883,752...244,887,657
JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO Aphidicolin results in increased expression of FGF8 mRNA CTD PMID:29990529 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:254,533,504...254,539,605
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Aphidicolin inhibits the reaction [Docetaxel results in increased expression of H2AX protein] CTD PMID:20878124 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO Aphidicolin results in decreased expression of HOXB9 mRNA CTD PMID:29990529 NCBI chr10:81,733,857...81,737,363
Ensembl chr10:81,733,658...81,738,872
JBrowse link
G Hoxc6 homeo box C6 decreases expression ISO Aphidicolin results in decreased expression of HOXC6 mRNA CTD PMID:29990529 NCBI chr 7:136,013,679...136,051,601
Ensembl chr 7:136,024,961...136,027,365
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases activity ISO
EXP
Aphidicolin results in decreased activity of POLA1 protein CTD PMID:224865 NCBI chr  X:62,028,475...62,342,455
Ensembl chr  X:62,028,476...62,342,355
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions ISO Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]] CTD PMID:18158334 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:98,544,954...98,762,108
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO Aphidicolin results in increased expression of RXRA mRNA CTD PMID:14738865 NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:31,388,223...31,474,417
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Aphidicolin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:161,064,812...161,070,372
Ensembl chr 3:161,059,931...161,088,765
JBrowse link
G Tbx6 T-box transcription factor 6 decreases expression ISO Aphidicolin results in decreased expression of TBX6 mRNA CTD PMID:29990529 NCBI chr 1:190,818,397...190,823,824
Ensembl chr 1:190,819,229...190,823,138
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 increases expression ISO Aphidicolin results in increased expression of TNFRSF8 protein CTD PMID:12441127 NCBI chr 5:162,406,387...162,451,620
Ensembl chr 5:162,406,387...162,451,620
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Trim28 tripartite motif-containing 28 multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein] CTD PMID:22003191 NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:82,724,838...82,731,572
JBrowse link
G Wnt3a Wnt family member 3A decreases expression ISO Aphidicolin results in decreased expression of WNT3A mRNA CTD PMID:29990529 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 decreases response to substance ISO XRCC4 results in decreased susceptibility to Aphidicolin CTD PMID:21785230 NCBI chr 2:22,686,506...22,932,929
Ensembl chr 2:22,686,508...22,933,160
JBrowse link
baicalin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
increases expression
EXP baicalin results in increased expression of and results in increased activity of ACHE protein
baicalin results in increased expression of ACHE mRNA
CTD PMID:27019979 NCBI chr12:25,042,882...25,050,608
Ensembl chr12:25,043,461...25,050,410
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity ISO baicalin results in increased activity of AHR protein CTD PMID:17869316 PMID:26204831 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of AIF1 protein] CTD PMID:38016618 NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,652,243...3,657,339
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO baicalin inhibits the reaction [oxophenylarsine results in decreased phosphorylation of AKT1 protein]; Niacinamide inhibits the reaction [baicalin inhibits the reaction [oxophenylarsine results in decreased phosphorylation of AKT1 protein]] CTD PMID:38865859 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alb albumin multiple interactions ISO baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of ALB protein] CTD PMID:35088608 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions EXP baicalin inhibits the reaction [Hydrogen Peroxide affects the localization of and results in increased activity of ALOX5 protein] CTD PMID:20139896 NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:151,203,949...151,251,126
JBrowse link
G Angpt1 angiopoietin 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA] CTD PMID:34414639 NCBI chr 7:75,415,959...75,668,696
Ensembl chr 7:75,418,218...75,668,696
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions EXP baicalin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of ATF2 protein] CTD PMID:24312512 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:79,126,705...79,202,745
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
baicalin results in increased expression of BAX protein
baicalin affects the reaction [Rotenone results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Rotenone results in increased expression of BAX protein]
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; baicalin inhibits the reaction [Gentamicins results in increased expression of BAX mRNA]; baicalin inhibits the reaction [Gentamicins results in increased expression of BAX protein]
baicalin inhibits the reaction [Rotenone affects the expression of BAX protein]
CTD PMID:21457722 PMID:25423838 PMID:31021006 PMID:34333357 PMID:35088608 More... NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
EXP
ISO
baicalin inhibits the reaction [Rotenone affects the expression of BCL2 protein]
baicalin results in decreased expression of BCL2 protein
baicalin affects the reaction [Rotenone results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Rotenone results in decreased expression of BCL2 protein]
baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; baicalin inhibits the reaction [Gentamicins results in decreased expression of BCL2 mRNA]; baicalin inhibits the reaction [Gentamicins results in decreased expression of BCL2 protein]
CTD PMID:25423838 PMID:31021006 PMID:34333357 PMID:35088608 PMID:36446982 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Casp1 caspase 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CASP1 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]] CTD PMID:38016618 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:10,746,333...10,882,275
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
baicalin inhibits the reaction [Rotenone affects the expression of CASP3 protein]
baicalin affects the reaction [Rotenone results in decreased activity of CASP3 protein]; baicalin inhibits the reaction [oxophenylarsine results in increased cleavage of CASP3 protein]
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; baicalin inhibits the reaction [Gentamicins results in increased cleavage of CASP3 protein]
CTD PMID:25423838 PMID:31021006 PMID:34333357 PMID:35088608 PMID:36446982 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions ISO baicalin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein] CTD PMID:34333357 PMID:35088608 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO baicalin results in decreased expression of CCNA2 protein CTD PMID:21457722 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
JBrowse link
G Ccnd1 cyclin D1 increases expression
decreases expression
multiple interactions
ISO baicalin results in increased expression of CCND1 mRNA
baicalin results in decreased expression of CCND1 protein
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of CCND1 mRNA]
CTD PMID:19160421 PMID:21457722 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions EXP baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:33,518,420...33,553,995
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A1 protein]; baicalin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
baicalin results in increased expression of CYP1A1 mRNA; baicalin results in increased expression of CYP1A1 protein
CTD PMID:18451504 PMID:26204831 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; 3',4'-dimethoxyflavone inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 mRNA]; resveratrol inhibits the reaction [baicalin results in increased expression of CYP1A2 protein]
baicalin results in increased expression of CYP1A2 mRNA; baicalin results in increased expression of CYP1A2 protein
CTD PMID:26204831 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Egf epidermal growth factor multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO baicalin inhibits the reaction [EGF protein results in increased phosphorylation of ELK1 protein] CTD PMID:25625231 NCBI chr  X:3,692,367...3,709,252
Ensembl chr  X:3,693,293...3,709,249
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased phosphorylation of ERN1 protein] CTD PMID:29031535 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,830,428...91,920,791
JBrowse link
G Foxa2 forkhead box A2 decreases expression ISO baicalin results in decreased expression of FOXA2 mRNA; baicalin results in decreased expression of FOXA2 protein CTD PMID:32687838 NCBI chr 3:155,923,305...155,927,508
Ensembl chr 3:155,923,307...155,928,757
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GOT1 protein] CTD PMID:15645217 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:252,284,434...252,329,871
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
baicalin inhibits the reaction [tert-Butylhydroperoxide results in increased activity of GPT protein]
baicalin inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein]
CTD PMID:15645217 PMID:35088608 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Hes1 hes family bHLH transcription factor 1 increases expression
multiple interactions
ISO baicalin results in increased expression of HES1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HES1 mRNA]
CTD PMID:19160421 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:84,210,633...84,213,061
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 increases expression
multiple interactions
ISO baicalin results in increased expression of HEY1 mRNA
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY1 mRNA]
CTD PMID:19160421 NCBI chr 2:95,003,935...95,006,457
Ensembl chr 2:95,002,943...95,007,624
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions
increases expression
ISO N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [baicalin results in increased expression of HEY2 mRNA] CTD PMID:19160421 NCBI chr 1:28,641,100...28,651,187
Ensembl chr 1:28,641,057...28,651,187
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of HMOX1 protein]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]; baicalin promotes the reaction [Carbon Tetrachloride results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]
baicalin results in increased expression of HMOX1 mRNA; baicalin results in increased expression of HMOX1 protein
CTD PMID:16824337 PMID:18187930 PMID:38016618 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hnf1a HNF1 homeobox A multiple interactions
decreases expression
ISO baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF1A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]
baicalin results in decreased expression of HNF1A mRNA; baicalin results in decreased expression of HNF1A protein
CTD PMID:32687838 NCBI chr12:47,299,171...47,333,457
Ensembl chr12:47,306,245...47,332,755
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha decreases expression
multiple interactions
ISO baicalin results in decreased expression of HNF4A protein
baicalin inhibits the reaction [HNF4A protein binds to HNF1A promoter]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A mRNA]; HNF4A protein promotes the reaction [baicalin results in decreased expression of HNF1A protein]; HNF4A protein promotes the reaction [baicalin results in decreased secretion of Hepatitis B Surface Antigens]
baicalin results in decreased expression of HNF4A mRNA; baicalin results in decreased expression of HNF4A protein
CTD PMID:32687838 NCBI chr 3:172,606,220...172,667,758
Ensembl chr 3:172,606,220...172,667,758
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein] CTD PMID:34414639 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:26,430,640...26,432,301
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of IL1B protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL1B protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]
baicalin inhibits the reaction [Rotenone results in increased expression of IL1B protein]
CTD PMID:29031535 PMID:35088608 PMID:36446982 PMID:38016618 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
EXP
ISO
baicalin results in decreased expression of IL6 mRNA; baicalin results in decreased expression of IL6 protein
baicalin inhibits the reaction [ethanol increases expression of IL6 protein in liver]
baicalin inhibiits the reaction [ischemia-reperfusion injury increases expression of IL6 mRNA in liver and protein in serum]
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased secretion of IL6 protein]
CTD
RGD
PMID:22019745 PMID:29031535 PMID:34333357 PMID:35088608 PMID:38016618 More... RGD:598148158, RGD:598147059 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Ins1 insulin 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein] CTD PMID:34414639 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Itga4 integrin subunit alpha 4 multiple interactions EXP baicalin inhibits the reaction [ITGA4 protein results in increased expression of KDR protein]; baicalin inhibits the reaction [ITGA4 protein results in increased expression of VEGFA protein] CTD PMID:36731809 NCBI chr 3:84,569,487...84,646,276
Ensembl chr 3:84,560,369...84,641,039
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO baicalin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of JAK2 protein] CTD PMID:35088608 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:236,408,662...236,468,762
JBrowse link
G Kdr kinase insert domain receptor multiple interactions EXP baicalin inhibits the reaction [ITGA4 protein results in increased expression of KDR protein] CTD PMID:36731809 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,572,049...32,615,192
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of KEAP1 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein] CTD PMID:38016618 NCBI chr 8:28,044,555...28,054,042
Ensembl chr 8:28,044,555...28,054,042
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein] CTD PMID:34414639 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein] CTD PMID:34414639 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO baicalin inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPK8 protein]; Niacinamide inhibits the reaction [baicalin inhibits the reaction [oxophenylarsine results in increased phosphorylation of MAPK8 protein]] CTD PMID:38865859 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions EXP baicalin inhibits the reaction [ischemia-reperfusion injury increases expression of COX2 mRNA and protein in liver] RGD PMID:22019745 RGD:598147059 NCBI chr MT:7,006...7,689
Ensembl chr MT:6,991...7,674
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor decreases expression
multiple interactions
EXP baicalin results in decreased expression of MYD88 protein
baicalin inhibits the reaction [ischemia-reperfusion injury increases expression of Myd88 protein in liver]
CTD
RGD
PMID:22019745 PMID:22019745 RGD:598147059 NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:127,952,161...127,956,230
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] affects the localization of NFE2L2 protein; baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of NFE2L2 protein]; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] CTD PMID:38016618 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
EXP baicalin results in increased expression of NFKBIA protein
baicalin inhibits the reaction [ischemia-reperfusion injury increases expression of NfKbia protein in liver]
CTD
RGD
PMID:22019745 PMID:22019745 RGD:598147059 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]] CTD PMID:29031535 PMID:38016618 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP
ISO
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; mifobate inhibits the reaction [baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]
baicalin inhibits the reaction [ischemia-reperfusion injury increases expression of NOS2 mRNA and protein in liver]
baicalin results in decreased expression of NOS2 mRNA; baicalin results in decreased expression of NOS2 protein
baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of NOS2 protein]
CTD
RGD
PMID:18187930 PMID:22019745 PMID:24312512 PMID:22019745 RGD:598147059 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Notch1 notch receptor 1 increases activity
increases expression
ISO baicalin results in increased activity of NOTCH1 protein
baicalin results in increased expression of NOTCH1 mRNA
CTD PMID:19160421 NCBI chr 3:29,676,040...29,721,613
Ensembl chr 3:29,676,171...29,721,613
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 increases expression ISO Baicalin increases expression of NR1H3 mRNA and protein in foam cells RGD PMID:27389392 RGD:401842390 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:97,614,616...97,624,532
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [baicalin inhibits the reaction [oxophenylarsine results in increased cleavage of PARP1 protein]]; baicalin inhibits the reaction [oxophenylarsine results in increased cleavage of PARP1 protein]; Niacinamide inhibits the reaction [baicalin inhibits the reaction [oxophenylarsine results in increased cleavage of PARP1 protein]] CTD PMID:38865859 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions ISO baicalin inhibits the reaction [oxophenylarsine results in decreased phosphorylation of PDK1 protein]; Niacinamide inhibits the reaction [baicalin inhibits the reaction [oxophenylarsine results in decreased phosphorylation of PDK1 protein]] CTD PMID:38865859 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:77,113,473...77,144,145
JBrowse link
G Pkm pyruvate kinase M1/2 increases activity ISO baicalin results in increased activity of PKM protein CTD PMID:25388478 NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:68,948,815...68,975,396
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions EXP baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of and results in decreased activity of PPARG protein] CTD PMID:24312512 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression EXP baicalin results in increased expression of PRIMA1 mRNA CTD PMID:27019979 NCBI chr 6:128,094,686...128,155,592
Ensembl chr 6:128,103,175...128,154,865
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO baicalin inhibits the reaction [oxophenylarsine results in increased phosphorylation of PRKCD protein] CTD PMID:38865859 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP baicalin results in decreased expression of PTGS2 mRNA; baicalin results in decreased expression of PTGS2 protein CTD PMID:22019745 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of PYCARD protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]] CTD PMID:38016618 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:192,032,124...192,033,419
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP
ISO
baicalin affects the localization of and results in decreased expression of RELA protein
baicalin inhibits the reaction [ischemia-reperfusion injury increases expression of NfKb protein in liver]
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of and results in increased phosphorylation of RELA protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]]
CTD
RGD
PMID:22019745 PMID:34333357 PMID:38016618 PMID:22019745 RGD:598147059 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO baicalin inhibits the reaction [oxophenylarsine results in decreased expression of SIRT3 protein]; Niacinamide inhibits the reaction [baicalin inhibits the reaction [oxophenylarsine results in decreased expression of SIRT3 protein]] CTD PMID:38865859 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076
JBrowse link
G Snca synuclein alpha multiple interactions ISO [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] affects the localization of NFE2L2 protein; [baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL6 mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of TNF mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]; baicalin inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased ubiquitination of NFE2L2 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in decreased expression of KEAP1 protein]; baicalin promotes the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; baicalin promotes the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [[baicalin co-treated with 1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of CASP1 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of IL1B protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of NLRP3 protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of PYCARD protein]]; NFE2L2 protein affects the reaction [baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased phosphorylation of RELA protein]] CTD PMID:38016618 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:91,026,474...91,126,315
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO baicalin inhibits the reaction [oxophenylarsine results in decreased activity of SOD2 protein]; Niacinamide inhibits the reaction [baicalin inhibits the reaction [oxophenylarsine results in decreased activity of SOD2 protein]] CTD PMID:38865859 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO baicalin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of STAT3 protein] CTD PMID:35088608 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Tek TEK receptor tyrosine kinase multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA] CTD PMID:34414639 NCBI chr 5:114,722,815...114,849,535
Ensembl chr 5:114,723,006...114,849,991
JBrowse link
G Tfam transcription factor A, mitochondrial decreases expression
multiple interactions
ISO baicalin results in decreased expression of TFAM mRNA
baicalin inhibits the reaction [Rotenone results in decreased expression of TFAM mRNA]
CTD PMID:36446982 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; baicalin inhibits the reaction [TGFB1 protein results in increased expression of COL1A2 mRNA] CTD PMID:19474275 PMID:34414639 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TH protein] CTD PMID:38016618 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:207,500,962...207,557,227
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression
multiple interactions
EXP
ISO
baicalin results in decreased expression of TLR4 protein
baicalin inhibits the reaction [ischemia-reperfusion injury increases expression of Tlr4 protein in liver]
baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of TLR4 protein]
baicalin inhibits the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]
CTD
RGD
PMID:22019745 PMID:24312512 PMID:34333357 PMID:22019745 RGD:598147059 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
baicalin inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF mRNA]; baicalin inhibits the reaction [[1-Methyl-4-phenylpyridinium co-treated with SNCA protein] results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]; baicalin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]
baicalin results in decreased expression of TNF mRNA; baicalin results in decreased expression of TNF protein
baicalin inhibits the reaction [Paraquat results in increased expression of TNF protein]
CTD PMID:16824337 PMID:18187930 PMID:22019745 PMID:34333357 PMID:35088608 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tp53 tumor protein p53 increases expression ISO baicalin results in increased expression of TP53 protein CTD PMID:21457722 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]; dorsomorphin inhibits the reaction [baicalin inhibits the reaction [Palmitic Acid results in increased expression of TXNIP protein]] CTD PMID:29031535 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 multiple interactions ISO baicalin inhibits the reaction [oxophenylarsine results in decreased expression of UHRF1 protein] CTD PMID:38865859 NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,222,063...1,241,792
JBrowse link
G Usp27x ubiquitin specific peptidase 27, X-linked multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein] CTD PMID:34414639 NCBI chr  X:17,795,506...17,798,741
Ensembl chr  X:17,794,884...17,798,879
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP baicalin inhibits the reaction [ITGA4 protein results in increased expression of VEGFA protein] CTD PMID:36731809 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions EXP baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA] CTD PMID:34414639 NCBI chr16:44,445,293...44,560,887
Ensembl chr16:44,445,293...44,560,887
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO baicalin inhibits the reaction [[Biological Products co-treated with potassium oxonate] results in increased activity of XDH protein] CTD PMID:34044073 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350
JBrowse link
daidzein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA CTD PMID:16963248 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:72,473,676...72,596,473
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO daidzein inhibits the reaction [Elacridar inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]] CTD PMID:34217736 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO daidzein promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:16156793 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO daidzein inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:16156793 NCBI chr15:101,948,387...102,182,912
Ensembl chr15:101,949,433...102,181,375
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO daidzein inhibits the reaction [ABCC5 protein results in decreased susceptibility to Thioguanine]; daidzein inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] CTD PMID:16156793 NCBI chr11:93,975,579...94,071,659
Ensembl chr11:93,978,274...94,071,655
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects transport ISO ABCG2 protein affects the transport of daidzein CTD PMID:18322075 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:89,005,969...89,132,493
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:87,563,601...87,613,078
Ensembl chr 9:87,563,601...87,613,097
JBrowse link
G Add2 adducin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ADD2 mRNA CTD PMID:16963248 NCBI chr 4:120,001,977...120,101,090
Ensembl chr 4:120,002,054...120,101,091
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects binding
increases activity
ISO daidzein binds to and results in increased activity of AHR protein
daidzein binds to AHR protein
daidzein results in increased activity of AHR protein
CTD PMID:14644660 PMID:17869316 PMID:20436506 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:80,758,142...80,837,883
JBrowse link
G Alpg alkaline phosphatase, germ cell increases expression ISO daidzein metabolite results in increased expression of ALPG mRNA CTD PMID:15993745 NCBI chr 9:95,187,995...95,205,127
Ensembl chr 9:95,198,334...95,205,742
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [daidzein binds to ESR1 protein] which results in increased activity of ALPL protein; fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:143,176,645...143,219,447
Ensembl chr 1:143,176,645...143,195,101
JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
ISO
EXP
daidzein promotes the reaction [TGFB1I1 protein results in increased activity of AR protein]
daidzein inhibits the reaction [Flutamide results in decreased expression of AR mRNA]; daidzein inhibits the reaction [Flutamide results in decreased expression of AR protein]
daidzein results in decreased expression of AR mRNA
CTD PMID:10822019 PMID:17252558 PMID:23135684 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:67,135,317...67,304,467
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO daidzein results in decreased expression of ARHGDIA mRNA CTD PMID:15757668 NCBI chr10:106,352,858...106,356,347
Ensembl chr10:106,353,491...106,356,347
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:105,818,203...105,850,379
Ensembl chr 4:105,818,203...105,850,379
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ATP6V0A2 mRNA CTD PMID:16963248 NCBI chr12:37,608,211...37,640,860
Ensembl chr12:37,472,813...37,640,860
JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of BAZ1A mRNA CTD PMID:16963248 NCBI chr 6:78,124,872...78,247,672
Ensembl chr 6:78,124,872...78,247,648
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:191,945,809...191,950,480
Ensembl chr 1:191,946,471...191,953,453
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO daidzein results in decreased expression of BCL2 protein CTD PMID:12791511 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO daidzein results in decreased expression of BCL2L1 protein CTD PMID:12791511 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO [daidzein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA CTD PMID:19347870 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:64,106,809...64,135,749
Ensembl chr 4:64,106,804...64,135,627
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO daidzein results in increased expression of BRCA1 mRNA CTD PMID:17266178 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,917,693...86,977,763
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B affects expression ISO daidzein affects the expression of BUB1B mRNA CTD PMID:15721199 NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:126,017,045...126,069,796
JBrowse link
G C3 complement C3 increases expression EXP daidzein results in increased expression of C3 mRNA CTD PMID:10822019 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,174,412...2,201,339
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:83,486,396...83,499,421
Ensembl chr 1:83,486,396...83,499,421
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:74,970,917...74,981,298
Ensembl chr13:74,970,923...74,981,505
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
ISO
EXP
daidzein results in increased activity of CASP3 protein
daidzein results in increased expression of CASP3 protein
CTD PMID:12791511 PMID:29217487 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:51,810,972...51,848,632
JBrowse link
G Cat catalase multiple interactions ISO
EXP
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
daidzein inhibits the reaction [Flutamide results in decreased activity of CAT protein]
CTD PMID:22981962 PMID:23135684 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO daidzein results in decreased expression of CCNA2 CTD PMID:21161820 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO daidzein results in increased expression of CCND1 mRNA CTD PMID:17266178 PMID:19800779 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:69,392,943...69,427,213
Ensembl chr11:69,392,975...69,427,128
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein] CTD PMID:21945492 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:21945492 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:75,760,147...75,797,540
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] CTD PMID:21945492 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:77,647,600...77,725,361
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
ISO daidzein promotes the reaction [CDKN1A protein binds to CDK2 protein]
daidzein results in decreased activity of CDK2 protein
CTD PMID:11322924 NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,714,392...1,721,878
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity ISO daidzein results in decreased activity of CDK4 protein CTD PMID:21161820 NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:64,771,147...64,775,163
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO daidzein promotes the reaction [CDKN1A protein binds to CDK2 protein]; ESR2 affects the reaction [daidzein results in increased expression of CDKN1A] CTD PMID:11322924 PMID:21161820 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:38,923,154...38,997,881
Ensembl chr12:38,922,330...38,954,783
JBrowse link
G Chat choline O-acetyltransferase increases activity ISO daidzein results in increased activity of CHAT protein CTD PMID:16428827 NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,663,665...7,723,416
JBrowse link
G Ckb creatine kinase B increases activity
multiple interactions
ISO daidzein results in increased activity of CKB protein
Glucose inhibits the reaction [daidzein results in increased activity of CKB protein]
CTD PMID:16621514 NCBI chr 6:136,550,583...136,553,464
Ensembl chr 6:136,549,844...136,553,478
JBrowse link
G Clu clusterin decreases expression EXP daidzein results in decreased expression of CLU mRNA CTD PMID:10822019 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:44,359,914...44,375,860
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
multiple interactions
decreases expression
ISO daidzein results in decreased activity of COMT protein
daidzein inhibits the reaction [COMT protein results in increased methylation of 4-hydroxyestradiol]; fulvestrant inhibits the reaction [daidzein results in decreased expression of COMT mRNA]
CTD PMID:18192686 PMID:18497090 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
JBrowse link
G Cox7a2l cytochrome c oxidase subunit 7A2 like increases expression ISO daidzein results in increased expression of COX7A2L mRNA CTD PMID:17266178 NCBI chr 6:16,936,574...16,950,797
Ensembl chr 6:16,936,795...16,950,798
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO daidzein results in increased expression of CPT1A mRNA; daidzein results in increased expression of CPT1A protein CTD PMID:16362726 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP daidzein results in increased phosphorylation of and results in increased activity of CREB1 protein CTD PMID:16972265 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:73,397,306...73,466,339
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Genistein co-treated with daidzein] results in decreased expression of CRP protein CTD PMID:16332659 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 affects expression ISO daidzein affects the expression of CSNK2A2 mRNA CTD PMID:15721199 NCBI chr19:9,562,340...9,602,136
Ensembl chr19:9,562,321...9,602,136
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
multiple interactions
ISO daidzein results in increased expression of CXCL12 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of CXCL12 mRNA]
CTD PMID:23384675 PMID:28396216 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:152,060,780...152,073,627
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:76,342,231...76,369,846
Ensembl chr 3:76,342,404...76,370,061
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
multiple interactions
decreases expression
ISO daidzein results in decreased activity of CYP19A1 protein
[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein; [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA
daidzein results in decreased expression of CYP19A1 mRNA
CTD PMID:16023337 PMID:16965912 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:63,449,148...63,476,917
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
decreases expression
ISO
EXP
daidzein results in decreased activity of CYP1A1 protein
daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]
daidzein results in decreased expression of CYP1A1 mRNA
daidzein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; fulvestrant inhibits the reaction [daidzein results in decreased expression of CYP1A1 mRNA]
CTD PMID:9395520 PMID:18420780 PMID:18451504 PMID:18497090 PMID:28985473 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO daidzein results in decreased activity of CYP1A2 protein CTD PMID:18420780 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects chemical synthesis
decreases activity
ISO CYP1B1 protein affects the chemical synthesis of daidzein
daidzein results in decreased activity of CYP1B1 protein
CTD PMID:15479032 PMID:18420780 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases activity ISO daidzein results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 1:91,299,584...91,307,650
Ensembl chr 1:91,299,561...91,307,649
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO daidzein results in decreased activity of CYP2C29 protein CTD PMID:18420780 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO daidzein results in decreased activity of CYP2D6 protein
daidzein results in decreased activity of CYP2D22 protein
CTD PMID:18420780 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
ISO
EXP
daidzein results in decreased activity of CYP2E1 protein
daidzein inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]
CTD PMID:18420780 PMID:31870919 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
decreases activity
EXP
ISO
daidzein results in increased expression of CYP3A4 mRNA
daidzein results in decreased activity of CYP3A4 protein
CTD PMID:18420780 PMID:31870919 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Dedd death effector domain-containing affects expression ISO daidzein affects the expression of DEDD mRNA CTD PMID:15721199 NCBI chr13:86,286,341...86,301,789
Ensembl chr13:86,288,350...86,302,446
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:196,661,465...196,680,505
Ensembl chr 2:196,661,345...196,682,397
JBrowse link
G Dio1 iodothyronine deiodinase 1 affects expression EXP daidzein affects the expression of DIO1 mRNA CTD PMID:24793811 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:32,507,316...32,621,678
Ensembl chr 6:32,512,070...32,614,970
JBrowse link
G Dock3 dedicator of cyto-kinesis 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of DOCK3 mRNA CTD PMID:16963248 NCBI chr 8:116,431,158...116,782,218
Ensembl chr 8:116,431,159...116,782,195
JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:1,098,505...1,133,500
Ensembl chr 9:1,095,929...1,177,715
JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO daidzein results in decreased expression of DUSP4 mRNA CTD PMID:16865672 NCBI chr16:64,079,893...64,101,396
Ensembl chr16:64,079,893...64,093,700
JBrowse link
G Ebag9 estrogen receptor binding site associated antigen 9 increases expression ISO daidzein results in increased expression of EBAG9 mRNA CTD PMID:17266178 NCBI chr 7:77,695,213...77,713,565
Ensembl chr 7:77,695,072...77,713,557
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:197,869,873...197,908,693
Ensembl chr 1:197,870,962...197,908,731
JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:95,386,155...95,432,800
Ensembl chr 9:95,386,169...95,432,798
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR protein CTD PMID:19347870 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions EXP daidzein results in increased phosphorylation of and results in increased activity of ELK1 protein CTD PMID:16972265 NCBI chr  X:3,692,367...3,709,252
Ensembl chr  X:3,693,293...3,709,249
JBrowse link
G Eno3 enolase 3 decreases expression ISO daidzein results in decreased expression of ENO3 mRNA CTD PMID:15757668 NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,866,101...55,874,540
JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of EPHA1 mRNA CTD PMID:16963248 NCBI chr 4:72,213,022...72,227,543
Ensembl chr 4:72,213,037...72,227,474
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease affects expression ISO daidzein affects the expression of ERCC5 mRNA CTD PMID:15721199 NCBI chr 9:53,801,471...53,846,611
Ensembl chr 9:53,801,714...53,875,084
JBrowse link
G Espn espin multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ESPN mRNA CTD PMID:16963248 NCBI chr 5:167,909,271...167,943,168
Ensembl chr 5:167,909,271...167,942,984
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
increases activity
affects response to substance
affects binding
decreases expression
ISO
EXP
[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR1 protein] results in increased expression of BSP mRNA; daidzein binds to and results in increased activity of ESR1 protein; daidzein inhibits the reaction [bisphenol A results in decreased expression of ESR1 mRNA]; daidzein inhibits the reaction [Estradiol binds to ESR1 protein]; daidzein metabolite binds to and results in increased activity of ESR1 protein; daidzein metabolite promotes the reaction [NCOA2 protein binds to ESR1 protein]; daidzein promotes the reaction [Estradiol results in increased activity of ESR1 protein]; ESR1 protein affects the reaction [daidzein results in decreased expression of IL6 mRNA]; ESR1 protein affects the reaction [daidzein results in decreased secretion of IL6 protein]; ESR1 protein inhibits the reaction [daidzein results in increased expression of CXCL12 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of PGR mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of PRSS23 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of TFF1 mRNA]; Estradiol affects the reaction [daidzein metabolite affects the activity of ESR1 protein]; Fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein]
daidzein results in increased expression of ESR1 mRNA; daidzein results in increased expression of ESR1 protein
daidzein results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to daidzein
daidzein results in decreased expression of ESR1 mRNA; daidzein results in decreased expression of ESR1 protein
CTD PMID:9751507 PMID:12598185 PMID:12650720 PMID:14579009 PMID:15084758 More... NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:43,644,392...43,900,354
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
affects binding
affects response to substance
increases activity
ISO
EXP
[daidzein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BSP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; daidzein binds to and results in increased activity of ESR2 protein; daidzein inhibits the reaction [Estradiol binds to ESR2 protein]; daidzein inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]; daidzein metabolite binds to and results in increased activity of ESR2 protein; daidzein promotes the reaction [Estradiol results in increased activity of ESR2 protein]; ESR2 affects the reaction [daidzein results in increased expression of CDKN1A]; ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein]; ESR2 gene polymorphism affects the susceptibility to [Genistein co-treated with daidzein]; Estradiol affects the reaction [daidzein metabolite affects the activity of ESR2 protein]
daidzein results in increased expression of ESR2 mRNA; daidzein results in increased expression of ESR2 protein
[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA
daidzein binds to ESR2 protein
ESR2 affects the susceptibility to daidzein
daidzein results in increased activity of ESR2 protein
daidzein results in increased activity of ESR2 protein; daidzein results in increased activity of ESR2 protein alternative form
CTD PMID:9751507 PMID:12224631 PMID:15084758 PMID:15993745 PMID:16033089 More... NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO daidzein binds to and results in increased activity of ESRRA protein; daidzein binds to and results in increased activity of ESRRA protein mutant form; daidzein promotes the reaction [ESRRA protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 1:213,533,309...213,543,432
Ensembl chr 1:213,533,310...213,543,811
JBrowse link
G Esrrb estrogen-related receptor beta multiple interactions ISO daidzein binds to and results in increased activity of ESRRB protein; daidzein promotes the reaction [ESRRB protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 6:111,738,662...111,894,087
Ensembl chr 6:111,738,662...111,894,087
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO daidzein inhibits the reaction [bisphenol A results in increased expression of ESRRG mRNA]; daidzein inhibits the reaction [bisphenol A results in increased expression of ESRRG protein]; daidzein promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 PMID:32963737 NCBI chr13:101,699,043...102,316,877
Ensembl chr13:101,889,706...102,316,877
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [daidzein results in increased expression of FABP4 mRNA] CTD PMID:30920877 NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:93,488,271...93,492,972
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:87,894,049...87,904,213
Ensembl chr10:87,893,543...87,904,247
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:64,959,999...64,975,176
Ensembl chr 4:64,959,999...64,975,176
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:181,536,665...181,546,830
Ensembl chr 3:181,536,673...181,546,834
JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:30,595,082...30,598,007
Ensembl chr20:30,595,084...30,597,844
Ensembl chr 6:30,595,084...30,597,844
JBrowse link
G Fermt2 FERM domain containing kindlin 2 affects expression ISO daidzein affects the expression of FERMT2 mRNA CTD PMID:15721199 NCBI chr15:21,162,603...21,257,995
Ensembl chr15:21,162,605...21,258,115
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:30,484,600...30,599,898
Ensembl chr 7:30,484,600...30,595,806
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:52,881,091...52,954,540
Ensembl chr 9:52,880,998...52,923,326
JBrowse link
G Fmn2 formin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of FMN2 mRNA CTD PMID:16963248 NCBI chr13:88,986,863...89,303,789
Ensembl chr13:88,986,842...89,303,789
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO daidzein inhibits the reaction [Estradiol results in increased expression of FOS mRNA]
daidzein results in increased expression of FOS mRNA
CTD PMID:11473722 PMID:17142977 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:7,233,524...7,273,290
Ensembl chr16:7,233,606...7,273,285
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions EXP daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein] CTD PMID:16972265 NCBI chr 5:171,357,778...171,424,489
Ensembl chr 5:171,357,797...171,424,488
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:238,054,954...238,063,451
Ensembl chr11:58,096,362...58,096,565
Ensembl chr 2:58,096,362...58,096,565
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions ISO daidzein inhibits the reaction [bisphenol A results in decreased expression of GPER1 mRNA] CTD PMID:32963737 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:20,327,679...20,337,144
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression
multiple interactions
ISO daidzein results in increased expression of GREB1 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]; Fulvestrant inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]
CTD PMID:23384675 PMID:33405908 NCBI chr 6:45,169,289...45,321,973
Ensembl chr 6:45,169,289...45,291,126
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP daidzein inhibits the reaction [Flutamide results in decreased activity of GSR protein] CTD PMID:23135684 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:91,938,308...91,948,680
Ensembl chr 1:91,938,278...91,948,683
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:65,165,532...65,634,681
Ensembl chr13:65,165,532...65,634,519
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO daidzein inhibits the reaction [Colforsin results in increased expression of HSD3B2 mRNA] CTD PMID:23370353 NCBI chr 2:188,784,614...188,812,535
Ensembl chr 2:188,784,614...188,790,569
JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions ISO [daidzein co-treated with ESR1 protein] results in increased expression of BSP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BSP mRNA CTD PMID:19347870 NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,744,501...5,775,299
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IFRD2 mRNA CTD PMID:16963248 NCBI chr 8:117,139,612...117,144,834
Ensembl chr 8:117,139,550...117,144,836
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO daidzein results in decreased expression of IGF1R mRNA CTD PMID:16865672 NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:130,959,997...131,248,664
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO daidzein results in increased expression of IGFBP4 mRNA CTD PMID:15757668 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473
JBrowse link
G Il12a interleukin 12A multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:21945492 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997
JBrowse link
G Il12b interleukin 12B multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:21945492 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
JBrowse link
G Il17a interleukin 17A multiple interactions ISO daidzein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:25583575 NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:30,640,844...30,644,331
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO daidzein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA] CTD PMID:11473722 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:136,979,805...136,998,013
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO daidzein inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]
CTD PMID:17266178 PMID:22981962 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il4 interleukin 4 increases expression ISO daidzein results in increased expression of IL4 mRNA; daidzein results in increased expression of IL4 protein CTD PMID:16108819 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
decreases secretion
ISO daidzein inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; ESR1 protein affects the reaction [daidzein results in decreased expression of IL6 mRNA]; ESR1 protein affects the reaction [daidzein results in decreased secretion of IL6 protein]
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:17266178 PMID:21945492 PMID:21972936 PMID:22981962 PMID:27576059 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:177,582,164...177,645,221
JBrowse link
G Irf2bp1 interferon regulatory factor 2 binding protein 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IRF2BP1 mRNA CTD PMID:16963248 NCBI chr 1:87,780,782...87,783,483
Ensembl chr 1:87,779,406...87,785,661
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:175,694,638...175,704,125
Ensembl chr 2:175,695,615...175,705,095
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO daidzein results in increased expression of JUN mRNA CTD PMID:17266178 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Kat5 lysine acetyltransferase 5 multiple interactions ISO daidzein inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein] CTD PMID:23857583 NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:212,325,090...212,332,587
JBrowse link
G Kcng2 potassium voltage-gated channel modifier subfamily G member 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA CTD PMID:16963248 NCBI chr18:76,017,225...76,085,377
Ensembl chr18:76,018,047...76,083,688
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:155,238,124...155,316,121
Ensembl chr 4:155,238,044...155,316,121
JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:36,782,638...36,863,793
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO daidzein results in decreased expression of KLK3 mRNA CTD PMID:16865672 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:126,254,633...126,274,412
Ensembl chr 3:126,254,663...126,274,418
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO daidzein results in decreased expression of LAMP3 mRNA CTD PMID:20678512 NCBI chr11:94,657,817...94,726,451
Ensembl chr11:94,661,399...94,726,195
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:152,239,296...152,262,290
Ensembl chr 5:152,229,505...152,262,290
JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:49,305,693...49,347,970
Ensembl chr13:49,305,830...49,348,116
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:1,034,691...1,036,937
Ensembl chr 9:1,034,679...1,037,337
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:95,313,830...95,329,471
Ensembl chr 1:95,313,033...95,329,354
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
AG 1879 inhibits the reaction [daidzein results in increased phosphorylation of MAPK1 protein]
daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD PMID:16840783 PMID:16972265 PMID:24859791 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
AG 1879 inhibits the reaction [daidzein results in increased phosphorylation of MAPK3 protein]
daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD PMID:16840783 PMID:16972265 PMID:24859791 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Me1 malic enzyme 1 increases expression ISO daidzein results in increased expression of ME1 mRNA CTD PMID:16865672 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP daidzein inhibits the reaction [Flutamide results in increased expression of MMP9 mRNA] CTD PMID:23135684 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:30,545,794...30,553,987
Ensembl chr 6:30,545,794...30,553,987
JBrowse link
G Mt2 metallothionein 2 increases expression ISO daidzein results in increased expression of MT2A mRNA CTD PMID:10656621 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,837,927...10,838,709
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:186,410,851...186,421,024
Ensembl chr 2:186,412,291...186,421,026
JBrowse link
G Mybl1 MYB proto-oncogene like 1 increases expression
multiple interactions
ISO daidzein results in increased expression of MYBL1 mRNA
Fulvestrant inhibits the reaction [daidzein results in increased expression of MYBL1 mRNA]
CTD PMID:33405908 NCBI chr 5:14,365,768...14,401,012
Ensembl chr 5:14,365,768...14,399,588
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO daidzein results in increased expression of MYC mRNA CTD PMID:17266178 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:245,086,109...245,234,768
Ensembl chr 1:245,086,109...245,234,768
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions
increases expression
ISO [daidzein binds to THRB protein] promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [NCOA1 protein binds to THRB protein]
daidzein results in increased expression of NCOA1 mRNA; daidzein results in increased expression of NCOA1 protein
CTD PMID:27576059 PMID:29688519 NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:32,952,090...33,195,924
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO daidzein metabolite promotes the reaction [NCOA2 protein binds to ESR1 protein] CTD PMID:15084758 NCBI chr 5:10,618,712...10,852,776
Ensembl chr 5:10,618,722...10,852,776
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21972936 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:226,689,745...226,783,088
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:21972936 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:78,593,847...78,597,072
JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression ISO daidzein results in decreased expression of NKX3-1 mRNA CTD PMID:16865672 NCBI chr15:50,883,661...50,886,253
Ensembl chr15:50,883,597...50,886,251
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
daidzein results in decreased activity of NOS2 protein
CTD PMID:11308324 PMID:18274639 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nos3 nitric oxide synthase 3 increases activity ISO daidzein results in increased activity of NOS3 protein CTD PMID:16840783 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO daidzein results in decreased expression of NQO1 mRNA CTD PMID:18497090 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO daidzein binds to and results in increased activity of NR1I2 protein
daidzein binds to and results in decreased activity of NR1I2 protein
CTD PMID:16054614 PMID:33049310 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:75,965,632...76,002,380
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:134,247,192...134,268,041
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:42,875,221...42,896,046
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO daidzein results in increased expression of NRIP1 mRNA CTD PMID:15757668 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353
JBrowse link
G Olfml3 olfactomedin-like 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of OLFML3 mRNA CTD PMID:16963248 NCBI chr 2:193,932,665...193,935,494
Ensembl chr 2:193,932,665...193,935,494
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO daidzein results in increased cleavage of PARP1 protein CTD PMID:12791511 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO
EXP
daidzein results in decreased expression of PCNA
daidzein results in decreased expression of PCNA protein
CTD PMID:21161820 PMID:29217487 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pdlim2 PDZ and LIM domain 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PDLIM2 mRNA CTD PMID:16963248 NCBI chr15:51,647,195...51,659,904
Ensembl chr15:51,647,197...51,658,958
JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression ISO daidzein results in increased expression of PDZK1 mRNA CTD PMID:15757668 NCBI chr 2:187,064,995...187,096,348
Ensembl chr 2:187,065,013...187,096,806
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO daidzein results in increased expression of PGR mRNA; daidzein results in increased expression of PGR protein
ESR1 protein inhibits the reaction [daidzein results in increased expression of PGR mRNA]
CTD PMID:17142977 PMID:23384675 NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:14,354,398...14,413,271
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions EXP daidzein inhibits the reaction [Flutamide results in increased expression of PLAUR mRNA] CTD PMID:23135684 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:89,178,453...89,198,130
JBrowse link
G Plcb2 phospholipase C, beta 2 multiple interactions EXP daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein] CTD PMID:16972265 NCBI chr 3:126,134,925...126,158,303
Ensembl chr 3:126,138,736...126,158,221
JBrowse link
G Pnn pinin, desmosome associated protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PNN mRNA CTD PMID:16963248 NCBI chr 6:82,493,032...82,501,345
Ensembl chr 6:82,492,978...82,501,933
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 multiple interactions ISO daidzein promotes the reaction [ESRRA protein binds to PNRC1 protein]; daidzein promotes the reaction [ESRRB protein binds to PNRC1 protein]; daidzein promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 5:52,443,400...52,489,303
Ensembl chr 5:52,443,400...52,446,491
JBrowse link
G Pou4f2 POU class 4 homeobox 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of POU4F2 mRNA CTD PMID:16963248 NCBI chr19:46,390,958...46,394,599
Ensembl chr19:46,390,958...46,394,599
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:41,059,843...41,083,189
Ensembl chr19:41,059,843...41,086,494
JBrowse link
G Prkca protein kinase C, alpha increases activity EXP daidzein results in increased activity of PRKCA protein CTD PMID:16972265 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:93,388,991...93,787,572
JBrowse link
G Prkcb protein kinase C, beta increases activity EXP daidzein results in increased activity of PRKCB protein CTD PMID:16972265 NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:186,263,447...186,594,740
JBrowse link
G Prkcd protein kinase C, delta decreases expression ISO daidzein results in decreased expression of PRKCD mRNA CTD PMID:15757668 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,775,681...5,805,839
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP daidzein affects the localization of and results in increased activity of PRKCE protein CTD PMID:16972265 NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:13,718,050...14,204,288
JBrowse link
G Prkcg protein kinase C, gamma increases activity EXP daidzein results in increased activity of PRKCG protein CTD PMID:16972265 NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:74,748,272...74,774,814
JBrowse link
G Prl prolactin increases secretion EXP daidzein results in increased secretion of PRL protein CTD PMID:19400946 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:58,036,779...58,098,996
Ensembl chr 3:58,038,042...58,099,363
JBrowse link
G Prss23 serine protease 23 increases expression
multiple interactions
ISO daidzein results in increased expression of PRSS23 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of PRSS23 mRNA]
CTD PMID:23384675 NCBI chr 1:152,815,301...152,835,005
Ensembl chr 1:152,813,670...152,947,871
JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:34,941,445...35,027,460
Ensembl chr15:34,967,477...35,026,828
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [daidzein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
CTD PMID:16870006 PMID:19347870 PMID:21341175 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:119,572,295...119,597,405
Ensembl chr 8:119,575,868...119,598,108
JBrowse link
G Ptk2 protein tyrosine kinase 2 increases phosphorylation ISO daidzein results in increased phosphorylation of PTK2 protein CTD PMID:12421874 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:107,015,733...107,172,091
JBrowse link
G Rac1 Rac family small GTPase 1 increases activity ISO daidzein results in increased activity of RAC1 protein CTD PMID:24859791 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:45,189,768...45,255,277
Ensembl chr13:45,189,804...45,255,277
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease increases expression ISO daidzein results in increased expression of RBBP8 mRNA CTD PMID:15757668 NCBI chr18:3,198,188...3,263,643
Ensembl chr18:3,197,310...3,263,985
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein] CTD PMID:18274639 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:69,073,681...69,194,041
Ensembl chr 7:69,075,562...69,194,102
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO daidzein results in increased expression of RPS6KA3 mRNA CTD PMID:15757668 NCBI chr  X:39,325,926...39,432,017
Ensembl chr  X:39,325,926...39,433,678
JBrowse link
G RT1-Bb RT1 class II, locus Bb multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of H2-AB1 protein] CTD PMID:21945492 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,598,475...4,604,118
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,932,773...13,946,213
Ensembl chr17:13,928,444...13,947,197
JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:48,457,102...48,470,444
Ensembl chr12:48,456,932...48,473,154
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [daidzein results in increased expression of SGK1 mRNA] CTD PMID:33405908 NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:24,799,396...24,807,231
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA CTD PMID:16963248 NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:100,161,024...100,182,259
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:102,953,894...102,962,964
Ensembl chr 1:102,953,918...102,962,964
JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions
increases transport
ISO daidzein metabolite inhibits the reaction [SLC10A1 protein results in increased transport of estrone sulfate]; daidzein metabolite promotes the reaction [SLC10A1 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLC10A1 protein results in increased transport of daidzein metabolite]; Taurocholic Acid inhibits the reaction [SLC10A1 protein results in increased transport of daidzein metabolite] CTD PMID:25319728 NCBI chr 6:106,344,319...106,357,944
Ensembl chr 6:106,344,319...106,357,944
JBrowse link
G Slc10a6 solute carrier family 10 member 6 multiple interactions
increases transport
ISO daidzein inhibits the reaction [SLC10A6 protein results in increased transport of estrone sulfate]; daidzein metabolite inhibits the reaction [SLC10A6 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLC10A6 protein results in increased transport of daidzein metabolite] CTD PMID:25319728 NCBI chr14:6,385,348...6,407,532
Ensembl chr14:6,385,537...6,408,894
JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO daidzein results in decreased expression of SLC12A2 mRNA CTD PMID:15757668 NCBI chr18:53,546,263...53,614,478
Ensembl chr18:53,546,333...53,614,470
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:194,805,556...194,832,966
Ensembl chr 2:194,812,502...194,832,977
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases uptake ISO SLC22A8 protein results in increased uptake of daidzein analog CTD PMID:21244849 NCBI chr 1:214,925,506...214,945,516
Ensembl chr 1:214,925,508...214,946,588
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity
ISO daidzein inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
daidzein results in decreased activity of SLC2A1 protein
CTD PMID:14642735 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO daidzein results in increased expression of SLC7A5 mRNA CTD PMID:15757668 NCBI chr19:66,843,808...66,872,412
Ensembl chr19:66,843,808...66,872,412
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases transport
multiple interactions
ISO SLCO2B1 protein results in increased transport of daidzein metabolite
daidzein inhibits the reaction [SLCO2B1 protein results in increased transport of estrone sulfate]; daidzein metabolite inhibits the reaction [SLCO2B1 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLCO2B1 protein results in increased transport of daidzein metabolite]
CTD PMID:25319728 NCBI chr 1:163,371,410...163,419,412
Ensembl chr 1:163,371,410...163,419,279
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:79,478,804...79,608,118
Ensembl chr 5:79,478,912...79,607,052
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
affects response to substance
multiple interactions
ISO daidzein results in increased expression of SOD2 protein
SOD2 protein affects the susceptibility to daidzein
fulvestrant inhibits the reaction [daidzein results in increased expression of SOD2 protein]
CTD PMID:23526725 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:77,920,781...77,939,284
Ensembl chr 1:77,920,783...77,938,574
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]; daidzein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein] CTD PMID:18274639 PMID:21972936 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
JBrowse link
G Stc1 stanniocalcin 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNA CTD PMID:16963248 NCBI chr15:50,709,439...50,720,093
Ensembl chr15:50,709,415...50,720,082
JBrowse link
G Stk39 serine threonine kinase 39 decreases expression ISO daidzein results in decreased expression of STK39 mRNA CTD PMID:16865672 NCBI chr 3:73,321,522...73,588,397
Ensembl chr 3:73,321,522...73,586,740
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:26,544,059...26,576,365
Ensembl chr12:26,544,067...26,576,366
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO daidzein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] CTD PMID:15531517 NCBI chr 1:190,702,592...190,706,112
Ensembl chr 1:190,702,592...190,706,131
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:68,572,901...68,602,803
Ensembl chr 9:68,572,911...68,602,890
JBrowse link
G Tacr3 tachykinin receptor 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of TACR3 mRNA CTD PMID:16963248 NCBI chr 2:225,940,497...226,037,756
Ensembl chr 2:225,940,444...226,037,756
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:126,526,006...126,622,163
Ensembl chr 6:126,526,009...126,614,215
JBrowse link
G Tff1 trefoil factor 1 increases expression
multiple interactions
ISO daidzein results in increased expression of TFF1 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of TFF1 mRNA]
CTD PMID:16965913 PMID:23384675 NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,237,095...9,240,956
JBrowse link
G Tg thyroglobulin decreases expression EXP daidzein results in decreased expression of TG mRNA CTD PMID:24793811 NCBI chr 7:100,307,349...100,492,246
Ensembl chr 7:100,307,349...100,314,539
Ensembl chr 7:100,307,349...100,314,539
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 multiple interactions ISO daidzein promotes the reaction [TGFB1I1 protein results in increased activity of AR protein] CTD PMID:17252558 NCBI chr 1:192,258,992...192,265,903
Ensembl chr 1:192,258,598...192,265,903
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO daidzein results in increased expression of TGM2 mRNA; daidzein results in increased expression of TGM2 protein CTD PMID:24859791 NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:167,192,612...167,304,240
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions
affects binding
ISO daidzein promotes the reaction [Triiodothyronine results in increased activity of THRA protein]
daidzein binds to THRA protein
CTD PMID:29688519 NCBI chr10:84,198,141...84,225,659
Ensembl chr10:84,197,011...84,225,657
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO [daidzein binds to THRB protein] promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [Triiodothyronine results in increased activity of THRB protein] CTD PMID:29688519 NCBI chr15:10,115,954...10,465,231
Ensembl chr15:10,115,954...10,313,680
JBrowse link
G Thrsp thyroid hormone responsive increases expression EXP daidzein results in increased expression of THRSP mRNA CTD PMID:24793811 NCBI chr 1:161,134,640...161,138,964
Ensembl chr 1:161,133,453...161,139,827
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21945492 PMID:22981962 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA CTD PMID:16963248 NCBI chr 3:56,911,398...56,930,797
Ensembl chr 3:56,911,252...56,930,796
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions
increases expression
ISO Fulvestrant inhibits the reaction [daidzein results in increased expression of TNFRSF11B mRNA]; Fulvestrant inhibits the reaction [daidzein results in increased expression of TNFRSF11B protein]
daidzein results in increased expression of TNFRSF11B mRNA; daidzein results in increased expression of TNFRSF11B protein
CTD PMID:27576059 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
decreases expression
ISO Fulvestrant inhibits the reaction [daidzein results in decreased expression of TNFSF11 mRNA]; Fulvestrant inhibits the reaction [daidzein results in decreased expression of TNFSF11 protein]
daidzein results in decreased expression of TNFSF11 mRNA; daidzein results in decreased expression of TNFSF11 protein
CTD PMID:27576059 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link
G Tp53 tumor protein p53 increases expression ISO daidzein results in increased expression of TP53 protein CTD PMID:19800779 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 decreases expression
multiple interactions
ISO daidzein results in decreased expression of TP53I11 mRNA
[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA
CTD PMID:15757668 PMID:27424125 NCBI chr 3:99,600,213...99,615,462
Ensembl chr 3:99,600,159...99,615,432
JBrowse link
G Tpd52l1 TPD52 like 1 increases expression ISO daidzein results in increased expression of TPD52L1 mRNA CTD PMID:15757668 NCBI chr 1:27,991,114...28,109,767
Ensembl chr 1:27,991,131...28,110,158
JBrowse link
G Tpo thyroid peroxidase decreases expression
decreases activity
EXP
ISO
daidzein results in decreased expression of TPO mRNA
daidzein results in decreased activity of TPO protein
CTD PMID:24793811 PMID:31629072 NCBI chr 6:52,425,998...52,495,793
Ensembl chr 6:52,426,010...52,495,793
JBrowse link
G Tyr tyrosinase increases expression ISO daidzein results in increased expression of TYR mRNA CTD PMID:21071833 NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:150,527,687...150,622,857
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of UCHL1 mRNA CTD PMID:16963248 NCBI chr14:41,838,859...41,849,743
Ensembl chr14:41,838,861...41,849,417
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
increases activity
ISO UGT1A1 protein results in increased glucuronidation of daidzein
daidzein results in increased activity of UGT1A1 protein
CTD PMID:14557274 PMID:16051636 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of daidzein CTD PMID:14557274 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 increases expression ISO daidzein results in increased expression of UGT2B17 mRNA CTD PMID:16865672 NCBI chr14:21,378,882...21,390,631
Ensembl chr14:21,378,853...21,392,331
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein] CTD PMID:16332659 NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:206,723,044...206,742,801
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:14,317,083...14,343,724
Ensembl chr 5:14,316,918...14,347,778
JBrowse link
ellagic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 increases expression ISO Ellagic Acid results in increased expression of ACP3 mRNA CTD PMID:12002526 NCBI chr 8:113,784,372...113,833,033
Ensembl chr 8:113,785,032...113,833,033
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein] CTD PMID:32971123 NCBI chr 8:28,939,984...28,946,639
Ensembl chr 8:28,939,985...28,943,929
JBrowse link
G Agt angiotensinogen multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in decreased abundance of NADP]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of AGTR1 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of CYBA mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of MYH7 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NCF2 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NOS2 mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPA mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPB mRNA]; Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:38356441 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:69,421,638...69,446,944
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of AGTR1 protein] CTD PMID:38356441 NCBI chr17:34,383,397...34,435,523
Ensembl chr17:34,381,467...34,435,660
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Ellagic Acid results in increased expression of AIFM1 protein CTD PMID:23554011 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:132,528,107...132,567,237
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
Ellagic Acid results in increased phosphorylation of AKT1 protein
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of AKT1 protein]
CTD PMID:26986492 PMID:35236242 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Alb albumin multiple interactions
affects binding
ISO ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein]
Ellagic Acid binds to ALB protein
CTD PMID:6343536 PMID:25247703 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase decreases activity ISO Ellagic Acid results in decreased activity of ALKBH2 protein CTD PMID:31088072 NCBI chr12:48,156,825...48,161,489
Ensembl chr12:48,156,827...48,161,483
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO Ellagic Acid results in increased expression of ALPL mRNA CTD PMID:38145796 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
increases expression
ISO Ellagic Acid results in decreased expression of APAF1 mRNA
Ellagic Acid results in increased expression of APAF1 mRNA
CTD PMID:12002526 PMID:35179410 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:27,381,855...27,466,772
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP Ellagic Acid inhibits the reaction [Aluminum Chloride results in increased expression of APP protein] CTD PMID:34944019 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:37,506,408...37,722,971
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression ISO Ellagic Acid results in increased expression of ASCL1 mRNA CTD PMID:12002526 NCBI chr 7:23,790,642...23,793,509
Ensembl chr 7:23,790,360...23,798,231
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Ellagic Acid results in increased expression of ASNS mRNA CTD PMID:12002526 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Ellagic Acid results in increased expression of ATF3 mRNA CTD PMID:12002526 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
JBrowse link
G Atg5 autophagy related 5 increases expression ISO Ellagic Acid results in increased expression of ATG5 mRNA CTD PMID:12002526 NCBI chr20:49,380,835...49,471,826
Ensembl chr20:49,380,813...49,471,821
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Ellagic Acid results in increased expression of BAD protein CTD PMID:23554011 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of BAX mRNA]
Ellagic Acid results in increased expression of BAX mRNA
CTD PMID:29854611 PMID:35179410 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of BCL2 protein
Ellagic Acid results in decreased expression of BCL2 mRNA
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of BCL2 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of BCL2 mRNA]
[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]
CTD PMID:20103723 PMID:22386815 PMID:29854611 PMID:35179410 PMID:35236242 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Ellagic Acid results in decreased expression of BMP6 mRNA CTD PMID:12002526 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,523,704...26,675,261
JBrowse link
G Brf1 BRF1 general transcription factor IIIB subunit decreases expression ISO Ellagic Acid results in decreased expression of BRF1 mRNA CTD PMID:12002526 NCBI chr 6:137,854,055...137,902,629
Ensembl chr 6:137,855,449...137,902,386
JBrowse link
G Calr calreticulin decreases expression ISO Ellagic Acid results in decreased expression of CALR mRNA CTD PMID:12002526 NCBI chr19:40,213,367...40,218,262
Ensembl chr19:40,213,239...40,219,236
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
decreases activity
decreases expression
ISO
EXP
Ellagic Acid results in increased expression of CASP3 mRNA
Ellagic Acid inhibits the reaction [AGT protein results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [Aluminum Chloride results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased activity of CASP3 protein]; Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ellagic Acid promotes the reaction [sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; sinapinic acid promotes the reaction [Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]
Ellagic Acid results in increased expression of and results in increased activity of CASP3 protein
Ellagic Acid results in increased activity of CASP3 protein
Ellagic Acid results in decreased activity of CASP3 protein
Ellagic Acid results in decreased expression of CASP3 mRNA
CTD PMID:12002526 PMID:22386815 PMID:23554011 PMID:23811531 PMID:28815802 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Ellagic Acid results in increased expression of and results in increased activity of CASP9 protein CTD PMID:23554011 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase increases activity
multiple interactions
EXP Ellagic Acid results in increased activity of CAT protein
Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:20074268 PMID:24877639 PMID:29864931 PMID:35236242 PMID:36108929 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion ISO Ellagic Acid results in decreased secretion of CCL2 protein CTD PMID:20816778 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Ccng1 cyclin G1 decreases expression EXP ellagic acid inhibits the reaction [estrogen increases expression of Ccng1 mRNA and protein in rat mammary tissue] RGD PMID:23791885 RGD:151356928 NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,677,885...25,683,766
JBrowse link
G Cd14 CD14 molecule decreases expression ISO Ellagic Acid results in decreased expression of CD14 mRNA CTD PMID:20816778 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,608,883...28,611,292
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Ellagic Acid results in decreased expression of CDK1 protein CTD PMID:23554011 NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,265,289...19,280,455
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]
[Ellagic Acid co-treated with Quercetin] results in increased expression of CDKN1A mRNA; Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]]
Ellagic Acid results in increased expression of CDKN1A protein
CTD PMID:15735102 PMID:20103723 PMID:23554011 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Ellagic Acid results in increased expression of COL1A1 mRNA; Ellagic Acid results in increased expression of COL1A1 protein CTD PMID:38145796 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Ctsd cathepsin D multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:21762681 NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:206,956,944...206,968,821
JBrowse link
G Ctsk cathepsin K multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein] CTD PMID:32971123 NCBI chr 2:185,747,548...185,758,512
Ensembl chr 2:185,747,165...185,765,582
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of CYBA mRNA] CTD PMID:38356441 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
decreases activity
ISO Ellagic Acid results in decreased expression of CYP1A1 mRNA
Ellagic Acid results in decreased activity of CYP1A1 protein
CTD PMID:19329757 PMID:20816778 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
multiple interactions
ISO Ellagic Acid results in decreased activity of CYP1B1 protein
[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]
CTD PMID:19329757 PMID:20103723 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Daxx death-domain associated protein decreases expression ISO Ellagic Acid results in decreased expression of DAXX mRNA CTD PMID:12002526 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,971,941...4,977,720
JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO Ellagic Acid results in decreased expression of DFFA mRNA CTD PMID:12002526 NCBI chr 5:164,823,807...164,836,729
Ensembl chr 5:164,823,807...164,836,728
JBrowse link
G E4f1 E4F transcription factor 1 increases expression ISO Ellagic Acid results in increased expression of E4F1 mRNA CTD PMID:12002526 NCBI chr10:13,978,975...13,999,646
Ensembl chr10:13,978,990...13,990,506
JBrowse link
G Egr3 early growth response 3 decreases expression ISO Ellagic Acid results in decreased expression of EGR3 mRNA CTD PMID:12002526 NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712
JBrowse link
G Endog endonuclease G increases expression ISO Ellagic Acid results in increased expression of ENDOG protein CTD PMID:23554011 NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:33,846,885...33,849,573
JBrowse link
G Ep300 E1A binding protein p300 increases expression ISO Ellagic Acid results in increased expression of EP300 mRNA CTD PMID:12002526 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 increases expression ISO Ellagic Acid results in increased expression of EPS15 mRNA CTD PMID:12002526 NCBI chr 5:129,274,487...129,374,856
Ensembl chr 5:129,274,502...129,374,856
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Ellagic Acid results in increased expression of EZH1 mRNA CTD PMID:12002526 NCBI chr10:86,626,307...86,662,257
Ensembl chr10:86,626,308...86,652,620
JBrowse link
G F12 coagulation factor XII multiple interactions
increases activity
ISO ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein] CTD PMID:6343536 NCBI chr17:9,212,819...9,220,664
Ensembl chr17:9,212,819...9,220,664
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Ellagic Acid results in decreased expression of FGFR1 mRNA CTD PMID:12002526 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:73,194,631...73,249,855
JBrowse link
G Flna filamin A decreases expression ISO Ellagic Acid results in decreased expression of FLNA mRNA CTD PMID:12002526 NCBI chr  X:157,159,051...157,185,559
Ensembl chr  X:157,159,051...157,182,343
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:24877639 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Ellagic Acid co-treated with Resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein] CTD PMID:20103723 PMID:32971123 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Ellagic Acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased activity of GAL protein] CTD PMID:27965107 NCBI chr 1:210,079,709...210,084,572
Ensembl chr 1:210,079,702...210,084,229
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression ISO Ellagic Acid results in decreased expression of GPLD1 mRNA CTD PMID:12002526 NCBI chr17:40,512,659...40,560,483
Ensembl chr17:40,512,660...40,554,975
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO
Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of GPT protein]
Ellagic Acid inhibits the reaction [Diquat results in increased activity of GPT protein]
CTD PMID:24877639 PMID:29935397 PMID:35268077 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP
ISO
Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA]
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of GPX1 mRNA]
CTD PMID:29935397 PMID:35268077 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein] CTD PMID:24877639 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression ISO Ellagic Acid results in increased expression of GSTA4 mRNA CTD PMID:12002526 NCBI chr 8:87,947,247...87,964,490
Ensembl chr 8:87,930,566...87,964,488
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Ellagic Acid affects the expression of GSTT1 protein CTD PMID:9855024 NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,083...12,873,019
JBrowse link
G Gtf2e2 general transcription factor IIE subunit 2 increases expression ISO Ellagic Acid results in increased expression of GTF2E2 mRNA CTD PMID:12002526 NCBI chr16:65,102,386...65,152,563
Ensembl chr16:65,102,390...65,161,394
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 increases expression ISO Ellagic Acid results in increased expression of GTF2H4 mRNA CTD PMID:12002526 NCBI chr20:3,076,110...3,081,805
Ensembl chr20:3,076,088...3,081,760
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:21762681 NCBI chr12:32,337,281...32,350,838
Ensembl chr12:32,334,075...32,363,024
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Ellagic Acid results in decreased expression of HIF1A mRNA CTD PMID:12002526 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO Ellagic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:46,925,491...47,123,111
Ensembl chr11:46,925,491...47,105,082
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of HMOX1 mRNA; Ellagic Acid results in increased expression of HMOX1 protein
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of HMOX1 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein
CTD PMID:22386815 PMID:23546295 PMID:35268077 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene] CTD PMID:20103723 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
JBrowse link
G Ier2 immediate early response 2 increases expression ISO Ellagic Acid results in increased expression of IER2 mRNA CTD PMID:12002526 NCBI chr19:40,399,373...40,400,897
Ensembl chr19:40,398,160...40,402,708
JBrowse link
G Ifng interferon gamma multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG protein] CTD PMID:29854611 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO Ellagic Acid results in increased expression of IGFBP2 mRNA CTD PMID:12002526 NCBI chr 9:81,864,811...81,892,179
Ensembl chr 9:81,864,783...81,892,171
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO Ellagic Acid results in decreased expression of IGFBP4 mRNA CTD PMID:12002526 NCBI chr10:84,491,471...84,503,487
Ensembl chr10:84,485,775...84,503,473
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO
EXP
Ellagic Acid results in decreased expression of IL1B mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]
Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
CTD PMID:18377686 PMID:20816778 PMID:21762681 PMID:24877639 PMID:27965107 More... NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO Ellagic Acid results in decreased expression of IL1R1 mRNA CTD PMID:20816778 NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:50,000,566...50,076,579
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL6 protein] CTD PMID:21762681 PMID:24877639 PMID:27965107 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression ISO Ellagic Acid results in increased expression of INPP5D mRNA CTD PMID:12002526 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589
JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 increases expression ISO Ellagic Acid results in increased expression of IQGAP2 mRNA CTD PMID:12002526 NCBI chr 2:28,629,558...28,904,649
Ensembl chr 2:28,629,558...28,904,649
JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO Ellagic Acid results in increased expression of IRF9 mRNA CTD PMID:12002526 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:33,065,659...33,071,879
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Ellagic Acid results in decreased expression of JUN mRNA; Ellagic Acid results in decreased expression of JUN protein modified form CTD PMID:23811531 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 decreases expression ISO Ellagic Acid results in decreased expression of KLK3 mRNA CTD PMID:12002526 NCBI chr 1:103,539,527...103,543,586
Ensembl chr 1:103,539,527...103,543,586
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Ellagic Acid results in increased expression of LITAF mRNA CTD PMID:12002526 NCBI chr10:5,163,258...5,199,930
Ensembl chr10:5,163,242...5,199,930
JBrowse link
G Map1a microtubule-associated protein 1A decreases expression ISO Ellagic Acid results in decreased expression of MAP1A mRNA CTD PMID:12002526 NCBI chr 3:128,716,907...128,736,638
Ensembl chr 3:128,716,940...128,740,159
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 decreases expression ISO Ellagic Acid results in decreased expression of MAP3K1 mRNA; Ellagic Acid results in decreased expression of MAP3K1 protein CTD PMID:23811531 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:45,081,889...45,149,897
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP
Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]
Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]
CTD PMID:32971123 PMID:38356441 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression ISO Ellagic Acid results in increased expression of MAPK11 mRNA CTD PMID:23811531 NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:122,098,121...122,105,038
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein] CTD PMID:27965107 NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,751,357...6,812,294
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP
Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]
Ellagic Acid inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
CTD PMID:32971123 PMID:38356441 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein CTD PMID:15735102 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK9 protein CTD PMID:15735102 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases activity EXP Ellagic Acid results in decreased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:172,760,930...172,776,157
Ensembl chr 4:172,760,886...172,776,875
JBrowse link
G Mir140 microRNA 140 multiple interactions EXP ellagic acid inhibits the reaction [hypoxia and acute myocardial infarction decreases expression of mir140 RNA in cardiac muscle cells] RGD PMID:28922712 RGD:329347824 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:52,375,293...52,375,391
JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression ISO Ellagic Acid results in increased expression of MMD mRNA CTD PMID:12002526 NCBI chr10:75,570,366...75,598,610
Ensembl chr10:75,570,397...75,598,609
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
decreases activity
ISO Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein; zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein]
Ellagic Acid results in decreased expression of MMP2 mRNA
Ellagic Acid results in decreased activity of MMP2 protein
CTD PMID:21573219 PMID:35179410 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:30,327,643...30,355,856
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression
decreases activity
ISO Ellagic Acid results in decreased expression of MMP9 mRNA
Ellagic Acid results in decreased activity of MMP9 protein
CTD PMID:35179410 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of MYH7 mRNA] CTD PMID:38356441 NCBI chr15:32,416,525...32,439,851
Ensembl chr15:32,416,527...32,438,194
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NCF2 mRNA] CTD PMID:38356441 NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein] CTD PMID:32971123 NCBI chr18:76,321,386...76,430,997
Ensembl chr18:76,321,386...76,430,990
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions
increases expression
affects response to substance
ISO
EXP
Ellagic Acid affects the localization of NFE2L2 protein
Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFE2L2 protein]
Ellagic Acid results in increased expression of NFE2L2 mRNA
[Ellagic Acid co-treated with Diquat] results in increased expression of NFE2L2 mRNA; Ellagic Acid inhibits the reaction [Diquat results in decreased expression of NFE2L2 mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of NFE2L2 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of and affects the localization of NFE2L2 protein; [Paraquat co-treated with Ellagic Acid] results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of and affects the localization of NFE2L2 protein
Ellagic Acid results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Ellagic Acid
CTD PMID:22386815 PMID:23546295 PMID:30503583 PMID:35236242 PMID:35268077 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 decreases expression ISO Ellagic Acid results in decreased expression of NFKB2 mRNA CTD PMID:12002526 PMID:35179410 NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:255,107,374...255,114,637
JBrowse link
G Nnat neuronatin increases expression ISO Ellagic Acid results in increased expression of NNAT mRNA CTD PMID:12002526 NCBI chr 3:166,646,373...166,648,845
Ensembl chr 3:166,646,384...166,649,086
JBrowse link
G Nop56 NOP56 ribonucleoprotein decreases expression ISO Ellagic Acid results in decreased expression of NOP56 mRNA CTD PMID:12002526 NCBI chr 3:137,926,187...137,934,971
Ensembl chr 3:137,929,646...137,934,959
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
EXP
ISO
Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NOS2 mRNA]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein]
Ellagic Acid results in decreased expression of NOS2 mRNA
CTD PMID:28815802 PMID:35179410 PMID:38356441 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Npas2 neuronal PAS domain protein 2 increases expression ISO Ellagic Acid results in increased expression of NPAS2 mRNA CTD PMID:12002526 NCBI chr 9:48,959,225...49,138,036
Ensembl chr 9:48,959,148...49,138,037
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPA mRNA] CTD PMID:38356441 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP Ellagic Acid inhibits the reaction [AGT protein results in increased expression of NPPB mRNA] CTD PMID:38356441 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:163,699,839...163,701,310
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of NQO1 mRNA; Ellagic Acid results in increased expression of NQO1 protein
Ellagic Acid inhibits the reaction [Diquat results in decreased expression of NQO1 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 protein
CTD PMID:23546295 PMID:35268077 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:52,205,314...52,220,260
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Ellagic Acid results in increased activity of NR1I3 protein CTD PMID:21821919 NCBI chr13:86,165,327...86,170,362
Ensembl chr13:86,165,349...86,170,370
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase decreases activity ISO Ellagic Acid results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Ellagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:25247703 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA] CTD PMID:20103723 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 multiple interactions EXP Ellagic Acid inhibits the reaction [Rotenone results in increased nitrosation of and results in decreased activity of PDIA2 protein] CTD PMID:25247703 NCBI chr10:15,720,301...15,723,386
Ensembl chr10:15,720,301...15,723,396
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases activity ISO Ellagic Acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:164,865,830...164,882,029
JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases expression ISO Ellagic Acid results in decreased expression of PLA2G2A mRNA CTD PMID:20816778 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:156,359,725...156,362,297
JBrowse link
G Plp2 proteolipid protein 2 increases expression ISO Ellagic Acid results in increased expression of PLP2 mRNA CTD PMID:12002526 NCBI chr  X:17,506,153...17,509,552
Ensembl chr  X:17,506,059...17,509,550
JBrowse link
G Pml PML nuclear body scaffold decreases expression ISO Ellagic Acid results in decreased expression of PML mRNA CTD PMID:12002526 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:67,523,164...67,576,083
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Ellagic Acid results in decreased expression of PPARD mRNA CTD PMID:12002526 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,352,183...6,365,707
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Ellagic Acid results in increased expression of PPARG protein CTD PMID:23811531 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression
ISO Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA]
Ellagic Acid results in decreased expression of PPARGC1A mRNA
CTD PMID:30503583 NCBI chr14:63,073,505...63,729,215
Ensembl chr14:63,273,189...63,729,213
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 decreases expression ISO Ellagic Acid results in decreased expression of PRKG1 mRNA CTD PMID:12002526 NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:237,823,053...239,103,005
JBrowse link
G Ptn pleiotrophin decreases expression
increases expression
ISO Ellagic Acid results in decreased expression of PTN mRNA
Ellagic Acid results in increased expression of PTN mRNA
CTD PMID:12002526 NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:66,260,764...66,342,482
JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 increases expression ISO Ellagic Acid results in increased expression of PTPRN2 mRNA CTD PMID:12002526 NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:143,582,547...144,336,744
JBrowse link
G Ran RAN, member RAS oncogene family decreases expression ISO Ellagic Acid results in decreased expression of RAN mRNA CTD PMID:12002526 NCBI chr12:33,311,155...33,314,339
Ensembl chr12:33,311,158...33,314,317
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] CTD PMID:27965107 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:54,780,858...54,911,857
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of RECK mRNA; Ellagic Acid results in increased expression of RECK protein
zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein]
CTD PMID:21573219 NCBI chr 5:62,898,717...62,965,274
Ensembl chr 5:62,898,668...62,965,270
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions
ISO
EXP
Ellagic Acid results in decreased expression of RELA mRNA
Ellagic Acid inhibits the reaction [TNF protein affects the localization of and results in increased activity of RELA protein]
Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [AGT protein results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RELA protein]
CTD PMID:12002526 PMID:24877639 PMID:27473819 PMID:27965107 PMID:32971123 More... NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rgs5 regulator of G-protein signaling 5 decreases expression ISO Ellagic Acid results in decreased expression of RGS5 mRNA CTD PMID:12002526 NCBI chr13:84,381,077...84,417,875
Ensembl chr13:84,380,910...84,421,352
JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression ISO Ellagic Acid results in increased expression of RUNX2 mRNA; Ellagic Acid results in increased expression of RUNX2 protein CTD PMID:38145796 NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:23,664,952...23,990,027
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Ellagic Acid results in decreased expression of SCD mRNA CTD PMID:20816778 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:253,218,970...253,231,785
JBrowse link
G Septin2 septin 2 increases expression ISO Ellagic Acid results in increased expression of SEPTIN2 mRNA CTD PMID:12002526 NCBI chr 9:101,465,535...101,498,766
Ensembl chr 9:101,465,650...101,498,759
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Ellagic Acid inhibits the reaction [Aluminum Chloride results in decreased expression of SOD1 mRNA]; Ellagic Acid inhibits the reaction [Aluminum Chloride results in decreased expression of SOD1 protein] CTD PMID:34944019 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:42,942,678...42,948,399
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA] CTD PMID:29935397 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO Ellagic Acid results in decreased expression of SOD3 mRNA CTD PMID:12002526 NCBI chr14:62,822,865...62,828,602
Ensembl chr14:62,811,177...62,829,125
JBrowse link
G Sp7 Sp7 transcription factor increases expression ISO Ellagic Acid results in increased expression of SP7 mRNA; Ellagic Acid results in increased expression of SP7 protein CTD PMID:38145796 NCBI chr 7:135,363,193...135,373,376
Ensembl chr 7:135,363,199...135,373,559
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Ellagic Acid results in increased expression of SPP1 mRNA; Ellagic Acid results in increased expression of SPP1 protein CTD PMID:38145796 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,613,576...5,619,820
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions ISO Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein] CTD PMID:32971123 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
JBrowse link
G Star steroidogenic acute regulatory protein increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of STAR mRNA
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of STAR mRNA]
CTD PMID:30503583 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression
decreases expression
ISO Ellagic Acid results in increased expression of STAT3 mRNA
Ellagic Acid results in decreased expression of STAT3 mRNA
CTD PMID:12002526 PMID:20816778 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C decreases expression ISO Ellagic Acid results in decreased expression of TAF1C mRNA CTD PMID:12002526 NCBI chr19:64,561,079...64,567,599
Ensembl chr19:64,560,562...64,567,599
JBrowse link
G Tcf12 transcription factor 12 increases expression ISO Ellagic Acid results in increased expression of TCF12 mRNA CTD PMID:12002526 NCBI chr 8:81,371,201...81,682,337
Ensembl chr 8:81,373,321...81,679,922
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions
increases expression
ISO
EXP
Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]
Ellagic Acid inhibits the reaction [phosalone results in decreased activity of TERT protein]
Ellagic Acid results in increased expression of TERT mRNA alternative form
CTD PMID:19501078 PMID:27965107 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:31,466,056...31,488,111
JBrowse link
G Tfam transcription factor A, mitochondrial decreases expression ISO Ellagic Acid results in decreased expression of TFAM mRNA CTD PMID:12002526 NCBI chr20:17,355,373...17,367,422
Ensembl chr20:17,355,363...17,369,877
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of TGFB1 mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]
CTD PMID:12002526 PMID:24877639 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
EXP
ISO
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein]
Ellagic Acid inhibits the reaction [TNF protein affects the localization of and results in increased activity of RELA protein]; Ellagic Acid inhibits the reaction [TNF protein results in increased activity of and affects the secretion of CXCL8 protein]
Ellagic Acid results in decreased expression of TNF mRNA
CTD PMID:21762681 PMID:24877639 PMID:27473819 PMID:27965107 PMID:28815802 More... NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A multiple interactions
affects binding
ISO Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]
Ellagic Acid binds to TNFRSF11A protein
CTD PMID:32971123 NCBI chr13:22,442,930...22,501,257
Ensembl chr13:22,442,665...22,501,257
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions
affects binding
ISO Ellagic Acid inhibits the reaction [TNFSF11 protein binds to TNFRSF11A protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of CTSK protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of FOS protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC mRNA]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased expression of SRC protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK1 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of MAPK3 protein]; Ellagic Acid inhibits the reaction [TNFSF11 protein results in increased phosphorylation of RELA protein]
Ellagic Acid binds to TNFSF11 protein
CTD PMID:32971123 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein] CTD PMID:21762681 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of TP53 mRNA; Ellagic Acid results in increased expression of TP53 protein
Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]]
Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 protein]
CTD PMID:15735102 PMID:23554011 PMID:27965107 PMID:35179410 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 decreases expression ISO Ellagic Acid results in decreased expression of UGP2 mRNA CTD PMID:12002526 NCBI chr14:99,657,637...99,698,573
Ensembl chr14:99,657,639...99,698,002
JBrowse link
G Usp4 ubiquitin specific peptidase 4 decreases expression ISO Ellagic Acid results in decreased expression of USP4 mRNA CTD PMID:12002526 NCBI chr 8:117,912,576...117,957,934
Ensembl chr 8:117,914,614...117,957,949
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP Ellagic Acid inhibits the reaction [Carbon Tetrachloride results in increased expression of VEGFA protein] CTD PMID:35236242 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Ellagic Acid results in increased expression of WARS1 mRNA CTD PMID:12002526 NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression ISO Ellagic Acid results in decreased expression of WEE1 protein CTD PMID:23554011 NCBI chr 1:173,605,609...173,632,450
Ensembl chr 1:173,608,949...173,632,449
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression ISO Ellagic Acid results in decreased expression of ZBTB16 mRNA CTD PMID:12002526 NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:57,891,081...58,073,507
JBrowse link
G Zmym2 zinc finger MYM-type containing 2 increases expression ISO Ellagic Acid results in increased expression of ZMYM2 mRNA CTD PMID:12002526 NCBI chr15:35,151,356...35,224,528
Ensembl chr15:35,127,994...35,224,941
JBrowse link
favipiravir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression EXP favipiravir results in increased expression of BAX protein CTD PMID:37942797 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP favipiravir results in decreased expression of BCL2 protein CTD PMID:37942797 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Casp3 caspase 3 increases expression EXP favipiravir results in increased expression of CASP3 protein CTD PMID:37942797 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase decreases activity EXP favipiravir results in decreased activity of CAT protein CTD PMID:37942797 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Il6 interleukin 6 increases expression EXP favipiravir results in increased expression of IL6 protein CTD PMID:37942797 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Muc1 mucin 1, cell surface associated increases expression EXP favipiravir results in increased expression of MUC1 protein CTD PMID:37942797 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:176,933,047...176,938,491
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression EXP favipiravir results in increased expression of NOS2 protein CTD PMID:37942797 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP favipiravir results in increased expression of P2RX7 protein CTD PMID:37942797 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193
JBrowse link
G Polg DNA polymerase gamma, catalytic subunit affects binding ISO favipiravir binds to POLG1 protein CTD PMID:36152797 NCBI chr 1:142,792,119...142,808,933
Ensembl chr 1:142,792,119...142,808,838
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP favipiravir results in increased expression of RELA protein CTD PMID:37942797 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
lamivudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadsb acyl-CoA dehydrogenase, short/branched chain multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ACADSB mRNA CTD PMID:18313992 NCBI chr 1:195,619,088...195,660,564
Ensembl chr 1:195,619,038...195,660,561
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ACSL6 mRNA CTD PMID:18313992 NCBI chr10:38,940,668...38,999,515
Ensembl chr10:38,940,747...39,002,873
JBrowse link
G Acta2 actin alpha 2, smooth muscle decreases expression ISO Lamivudine results in decreased expression of ACTA2 protein CTD PMID:11738102 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ADIPOQ mRNA CTD PMID:16931933 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of AEBP1 mRNA CTD PMID:16931933 NCBI chr14:84,951,577...84,962,840
Ensembl chr14:84,952,822...84,962,843
JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of AFAP1 mRNA CTD PMID:15784690 NCBI chr14:78,967,961...79,081,032
Ensembl chr14:78,967,961...79,080,939
JBrowse link
G Alb albumin affects binding ISO Lamivudine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ALOX5AP mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ALOX5AP mRNA CTD PMID:16931933 NCBI chr12:10,785,254...10,809,295
Ensembl chr12:10,785,257...10,817,038
JBrowse link
G Aqp9 aquaporin 9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of AQP9 mRNA CTD PMID:18313992 NCBI chr 8:80,678,027...80,718,273
Ensembl chr 8:80,678,030...80,717,240
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ARPP21 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ARPP21 mRNA CTD PMID:16931933 NCBI chr 8:120,912,964...121,077,586
Ensembl chr 8:120,912,970...121,031,357
JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ASIC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ASIC2 mRNA CTD PMID:16931933 NCBI chr10:66,368,308...67,438,237
Ensembl chr10:66,368,310...66,636,245
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASNS mRNA CTD PMID:15784690 NCBI chr 4:36,752,061...36,769,970
Ensembl chr 4:36,751,802...36,776,050
JBrowse link
G Ass1 argininosuccinate synthase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ASS1 mRNA CTD PMID:15784690 NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:35,144,999...35,194,627
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATF3 mRNA CTD PMID:15784690 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:105,282,440...105,295,750
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ATP2A2 mRNA CTD PMID:11706060 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5F1C mRNA CTD PMID:18313992 NCBI chr17:73,333,584...73,355,872
Ensembl chr17:73,333,588...73,383,073
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5MC3 mRNA CTD PMID:18313992 NCBI chr 3:79,218,014...79,220,664
Ensembl chr 3:79,218,014...79,220,664
JBrowse link
G Atp5mf ATP synthase membrane subunit f multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5MF mRNA CTD PMID:18313992 NCBI chr12:14,535,435...14,542,007
Ensembl chr12:14,522,832...14,542,709
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5PD mRNA CTD PMID:18313992 NCBI chr10:101,156,673...101,161,926
Ensembl chr10:101,156,673...101,162,954
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ATP5PF mRNA CTD PMID:18313992 NCBI chr11:37,368,045...37,375,721
Ensembl chr11:37,368,042...37,375,466
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ATP5PO mRNA CTD PMID:18313992 NCBI chr11:44,651,171...44,657,483
Ensembl chr11:44,651,173...44,657,520
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of BCL2 mRNA CTD PMID:18313992 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Lamivudine results in increased expression of BNIP3L protein CTD PMID:23640862 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:45,334,537...45,373,282
JBrowse link
G C1r complement C1r multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C1R mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C1R mRNA CTD PMID:16931933 NCBI chr 4:159,099,013...159,109,770
Ensembl chr 4:159,098,918...159,109,714
JBrowse link
G C3ar1 complement C3a receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C3AR1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of C3AR1 mRNA CTD PMID:16931933 NCBI chr 4:157,747,419...157,756,609
Ensembl chr 4:157,746,089...157,776,323
JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CARS1 mRNA CTD PMID:15784690 NCBI chr 1:208,183,092...208,225,425
Ensembl chr 1:208,182,788...208,225,407
JBrowse link
G Casp3 caspase 3 multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of CASP3 protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of CASP3 protein] CTD PMID:36309141 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in decreased activity of CAT protein CTD PMID:34118364 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccna2 cyclin A2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNA2 mRNA
Lamivudine results in decreased expression of CCNA2 mRNA
CTD PMID:15784690 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
JBrowse link
G Ccnc cyclin C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNC mRNA CTD PMID:15784690 NCBI chr 5:40,063,589...40,081,731
Ensembl chr 5:40,063,623...40,093,370
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CCND1 mRNA CTD PMID:15784690 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of CCND2 mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CCND2 mRNA
CTD PMID:15784690 NCBI chr 4:161,653,048...161,675,422
Ensembl chr 4:161,653,048...161,680,301
Ensembl chr 4:161,653,048...161,680,301
JBrowse link
G Ccne2 cyclin E2 multiple interactions
decreases expression
ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CCNE2 mRNA
Lamivudine results in decreased expression of CCNE2 mRNA
CTD PMID:15784690 NCBI chr 5:29,082,169...29,094,879
Ensembl chr 5:29,082,703...29,094,882
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CD36 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CD36 mRNA CTD PMID:16931933 NCBI chr 4:18,209,088...18,302,142 JBrowse link
G Cd44 CD44 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CD44 mRNA CTD PMID:15784690 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:109,612,054...109,699,424
JBrowse link
G Cd83 CD83 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CD83 mRNA CTD PMID:15784690 NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047
JBrowse link
G Cdk7 cyclin-dependent kinase 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CDK7 mRNA CTD PMID:15784690 NCBI chr 2:33,574,623...33,599,485
Ensembl chr 2:33,574,623...33,599,485
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of CDKN1A mRNA
[Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1A mRNA
CTD PMID:15784690 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1B mRNA CTD PMID:15784690 NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:169,490,876...169,496,498
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN1C mRNA CTD PMID:15784690 NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:208,084,787...208,087,498
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN2C mRNA CTD PMID:15784690 NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891
JBrowse link
G Cfd complement factor D multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CFD mRNA CTD PMID:16931933 NCBI chr 7:10,463,773...10,465,496
Ensembl chr 7:10,463,775...10,465,572
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CIDEC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CIDEC mRNA CTD PMID:16931933 NCBI chr 4:148,124,924...148,137,806
Ensembl chr 4:148,124,925...148,137,806
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CLCN3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of CLCN3 mRNA CTD PMID:16931933 NCBI chr16:34,138,004...34,210,984
Ensembl chr16:34,137,952...34,210,984
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Lamivudine results in decreased expression of COL3A1 protein CTD PMID:11738102 NCBI chr 9:54,866,646...54,902,578
Ensembl chr 9:54,866,632...54,903,232
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COMT mRNA CTD PMID:15784690 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX5A mRNA CTD PMID:18313992 NCBI chr 8:66,818,284...66,829,691
Ensembl chr 8:66,818,196...66,830,279
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX5B mRNA CTD PMID:18313992 NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6A1 mRNA CTD PMID:18313992 NCBI chr12:46,922,709...46,925,762
Ensembl chr12:46,912,648...46,925,768
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX6C mRNA CTD PMID:18313992 NCBI chr 7:69,014,410...69,027,145
Ensembl chr 7:69,014,417...69,027,166
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX7C mRNA CTD PMID:18313992 NCBI chr 2:18,577,145...18,579,170
Ensembl chr 2:18,577,149...18,579,170
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CPT1A mRNA CTD PMID:18313992 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
JBrowse link
G Crat carnitine O-acetyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CRAT mRNA CTD PMID:18313992 NCBI chr 3:34,073,504...34,087,099
Ensembl chr 3:34,073,506...34,087,099
JBrowse link
G Cul7 cullin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CUL7 mRNA CTD PMID:18313992 NCBI chr 9:21,816,703...21,830,344
Ensembl chr 9:21,816,703...21,830,344
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of CYB5A mRNA CTD PMID:18313992 NCBI chr18:80,487,923...80,520,544
Ensembl chr18:14,453,966...14,455,094
Ensembl chr18:14,453,966...14,455,094
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of CYP11A1 mRNA CTD PMID:18313992 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
JBrowse link
G Dck deoxycytidine kinase multiple interactions ISO DCK protein results in increased phosphorylation of and results in increased activity of Lamivudine CTD PMID:17530837 NCBI chr14:19,589,298...19,610,326
Ensembl chr14:19,589,298...19,610,326
JBrowse link
G Dcn decorin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DCN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNA CTD PMID:16931933 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:34,163,011...34,218,926
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Lamivudine results in increased expression of DDIT3 mRNA
[Zidovudine co-treated with Lamivudine] results in increased expression of DDIT3 mRNA
CTD PMID:15784690 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:65,005,501...65,006,509
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DHFR mRNA CTD PMID:15784690 NCBI chr 2:25,320,895...25,346,004 JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DIABLO mRNA CTD PMID:18313992 NCBI chr12:38,716,668...38,731,285
Ensembl chr12:38,716,668...38,731,265
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of DLST mRNA CTD PMID:18313992 NCBI chr 6:110,489,576...110,512,841
Ensembl chr 6:110,489,392...110,514,357
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of DNAJA3 mRNA CTD PMID:18313992 NCBI chr10:11,361,168...11,386,599
Ensembl chr10:11,361,168...11,386,599
JBrowse link
G Dusp3 dual specificity phosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DUSP3 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of DUSP3 mRNA CTD PMID:16931933 NCBI chr10:87,420,213...87,434,202
Ensembl chr10:87,419,494...87,434,063
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of ECHS1 mRNA CTD PMID:18313992 NCBI chr 1:204,324,679...204,333,506
Ensembl chr 1:204,324,682...204,333,506
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ECI1 mRNA CTD PMID:18313992 NCBI chr10:13,961,250...13,974,595
Ensembl chr10:13,961,218...13,974,773
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases secretion
ISO coenzyme Q10 inhibits the reaction [Lamivudine results in increased secretion of EDN1 protein] CTD PMID:23640862 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,660,799...22,666,687
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of EIF4EBP1 mRNA CTD PMID:15784690 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ELOVL3 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of ELOVL3 mRNA CTD PMID:16931933 NCBI chr 1:254,938,731...254,942,559
Ensembl chr 1:254,938,731...254,942,559
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of ESR2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA CTD PMID:16931933 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709
JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ETV6 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of ETV6 mRNA CTD PMID:16931933 NCBI chr 4:168,580,405...168,819,817
Ensembl chr 4:168,580,138...168,819,802
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FADS2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of FADS2 mRNA CTD PMID:16931933 NCBI chr 1:216,132,277...216,172,190
Ensembl chr 1:216,133,676...216,172,066
JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of FAIM mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of FAIM mRNA CTD PMID:16931933 NCBI chr 8:108,423,259...108,445,365
Ensembl chr 8:108,423,221...108,440,151
JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of FASN mRNA CTD PMID:11741158 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
JBrowse link
G Fdxr ferredoxin reductase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FDXR mRNA CTD PMID:18313992 NCBI chr10:101,006,845...101,015,582
Ensembl chr10:101,006,849...101,015,542
JBrowse link
G Fh fumarate hydratase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of FH1 mRNA CTD PMID:18313992 NCBI chr13:90,056,565...90,082,450
Ensembl chr13:90,056,570...90,089,627
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of G0S2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of G0S2 mRNA CTD PMID:16931933 NCBI chr13:107,335,036...107,335,948
Ensembl chr13:107,335,036...107,336,293
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of G6PC1 mRNA CTD PMID:16931933 NCBI chr10:86,807,659...86,819,023
Ensembl chr10:86,757,899...86,818,033
JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of GANC mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of GANC mRNA CTD PMID:16931933 NCBI chr 3:127,807,132...127,858,995
Ensembl chr 3:127,807,441...127,859,859
JBrowse link
G Gars1 glycyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of GARS1 mRNA CTD PMID:15784690 NCBI chr 4:85,484,939...85,542,876
Ensembl chr 4:85,493,753...85,542,876
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GAS1 mRNA CTD PMID:15784690 NCBI chr17:4,487,716...4,490,701
Ensembl chr17:4,484,283...4,497,657
JBrowse link
G Grhl2 grainyhead-like transcription factor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of GRHL2 mRNA CTD PMID:16931933 NCBI chr 7:70,280,360...70,415,277
Ensembl chr 7:70,285,310...70,415,274
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of GUCY1B1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of GUCY1B1 mRNA CTD PMID:16931933 NCBI chr 2:169,646,897...169,697,060
Ensembl chr 2:169,646,898...169,696,987
JBrowse link
G Gypa glycophorin A multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased mutagenesis of GYPA gene CTD PMID:17358027 NCBI chr19:44,354,669...44,370,304
Ensembl chr19:44,354,706...44,370,291
JBrowse link
G H4c8 H4 clustered histone 8 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of H4C9 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of H4C9 mRNA CTD PMID:16931933 NCBI chr17:47,176,246...47,180,690
Ensembl chr17:41,797,152...41,806,539
Ensembl chr17:41,797,152...41,806,539
Ensembl chr17:41,797,152...41,806,539
Ensembl chr 4:41,797,152...41,806,539
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of HADH mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of HADH mRNA CTD PMID:16931933 NCBI chr 2:222,462,049...222,504,446
Ensembl chr 2:222,462,049...222,504,446
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HADHA mRNA CTD PMID:18313992 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:31,907,291...31,947,698
JBrowse link
G Hax1 HCLS1 associated protein X-1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HAX1 mRNA CTD PMID:15784690 NCBI chr 2:177,731,918...177,735,670
Ensembl chr 2:177,731,921...177,735,390
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of HCN1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of HCN1 mRNA CTD PMID:16931933 NCBI chr 2:51,228,710...51,632,806
Ensembl chr 2:51,228,710...51,632,806
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HMGCS2 mRNA CTD PMID:18313992 NCBI chr 2:188,564,348...188,590,872
Ensembl chr 2:188,547,767...188,592,242
JBrowse link
G Hrk harakiri, BCL2 interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of HRK mRNA CTD PMID:16931933 NCBI chr12:44,048,402...44,070,561
Ensembl chr12:44,048,402...44,070,561
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B2 mRNA CTD PMID:18313992 NCBI chr 2:188,858,574...188,864,694 JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of HSD3B3 mRNA CTD PMID:18313992 NCBI chr 2:188,826,756...188,832,734
Ensembl chr 2:188,826,110...188,904,981
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH2 mRNA CTD PMID:18313992 NCBI chr 1:143,447,925...143,467,248
Ensembl chr 1:143,439,323...143,467,248
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IDH3A mRNA CTD PMID:18313992 NCBI chr 8:63,867,882...63,887,223
Ensembl chr 8:63,867,820...63,887,223
JBrowse link
G Idh3g isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of IDH3G mRNA CTD PMID:18313992 NCBI chr  X:156,666,573...156,675,482
Ensembl chr  X:156,666,577...156,675,799
JBrowse link
G Ifng interferon gamma increases expression ISO Lamivudine results in increased expression of IFNG protein CTD PMID:16250037 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Ikzf4 IKAROS family zinc finger 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of IKZF4 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of IKZF4 mRNA CTD PMID:16931933 NCBI chr 7:1,643,379...1,687,524
Ensembl chr 7:1,644,799...1,687,094
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of IL1B protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of IL1B protein] CTD PMID:36309141 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of IL27RA mRNA CTD PMID:15784690 NCBI chr19:41,014,730...41,026,740
Ensembl chr19:41,014,730...41,026,760
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of INPP5E mRNA CTD PMID:18313992 NCBI chr 3:29,614,868...29,627,542
Ensembl chr 3:29,614,868...29,627,542
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KCNG1 mRNA CTD PMID:15784690 NCBI chr 3:177,379,593...177,412,986
Ensembl chr 3:177,392,031...177,411,507
JBrowse link
G Kifc2 kinesin family member C2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of KIFC2 mRNA CTD PMID:16931933 NCBI chr 7:110,261,257...110,269,007
Ensembl chr 7:110,261,009...110,269,005
JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KLF4 mRNA CTD PMID:15784690 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:75,074,236...75,078,592
JBrowse link
G Klhl28 kelch-like family member 28 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of KLHL28 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of KLHL28 mRNA CTD PMID:16931933 NCBI chr 6:88,723,624...88,755,072
Ensembl chr 6:88,727,205...88,752,457
JBrowse link
G Krt7 keratin 7 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KRT7 mRNA CTD PMID:15784690 NCBI chr 7:134,407,626...134,423,787
Ensembl chr 7:134,407,584...134,423,786
JBrowse link
G Kynu kynureninase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of KYNU mRNA CTD PMID:15784690 NCBI chr 3:48,188,286...48,338,996
Ensembl chr 3:48,188,182...48,339,014
JBrowse link
G Lamb3 laminin subunit beta 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of LAMB3 mRNA CTD PMID:15784690 NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of LAMC2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA CTD PMID:16931933 NCBI chr13:67,835,199...67,894,694
Ensembl chr13:67,835,199...67,895,102
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEF1 mRNA CTD PMID:16931933 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929
JBrowse link
G Lep leptin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LEP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEP mRNA CTD PMID:16931933 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
JBrowse link
G Lpl lipoprotein lipase decreases expression
multiple interactions
ISO Lamivudine results in decreased expression of LPL mRNA
[Stavudine co-treated with Lamivudine co-treated with Indinavir] affects the expression of LPL mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of LPL mRNA; [Stavudine co-treated with Lamivudine] affects the expression of LPL mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of LPL mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of LPL mRNA
CTD PMID:11741158 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Mars1 methionyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MARS1 mRNA CTD PMID:15784690 NCBI chr 7:65,006,456...65,023,880
Ensembl chr 7:64,998,544...65,023,753
JBrowse link
G Me1 malic enzyme 1 multiple interactions
increases expression
ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Zidovudine co-treated with Lamivudine] affects the expression of ME1 mRNA
Lamivudine results in increased expression of ME1 mRNA
CTD PMID:11741158 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
JBrowse link
G Mfn1 mitofusin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN1 mRNA CTD PMID:18313992 NCBI chr 2:117,240,525...117,288,017
Ensembl chr 2:117,241,759...117,290,190
JBrowse link
G Mfn2 mitofusin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MFN2 mRNA CTD PMID:18313992 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:163,587,463...163,618,495
JBrowse link
G Mgat4c MGAT4 family, member C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MGAT4C mRNA CTD PMID:16931933 NCBI chr 7:38,596,117...39,361,103
Ensembl chr 7:38,596,065...39,362,078
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Lamivudine results in increased expression of MMP1 protein CTD PMID:15309715 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:12,943,453...12,963,964
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] promotes the reaction [[isoniazid, pyrazinamide, rifampin drug combination co-treated with Ethambutol] results in increased activity of MPO protein]; [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased activity of MPO protein CTD PMID:34118364 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Mrap melanocortin 2 receptor accessory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of MRAP mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of MRAP mRNA CTD PMID:16931933 NCBI chr11:43,477,382...43,489,118
Ensembl chr11:43,478,001...43,489,118
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX1 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,309...6,853
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of COX2 mRNA CTD PMID:18313992 NCBI chr MT:7,006...7,689
Ensembl chr MT:6,991...7,674
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of COX3 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,584...9,367
JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ND2 mRNA CTD PMID:18313992 NCBI chr MT:3,904...4,942
Ensembl chr MT:3,892...4,929
JBrowse link
G Mt-nd5 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of ND5 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr MT:11,736...13,565
Ensembl chr MT:11,721...13,553
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of MTHFD2 mRNA CTD PMID:15784690 NCBI chr 4:117,368,833...117,380,350
Ensembl chr 4:117,368,835...117,380,350
JBrowse link
G Myod1 myogenic differentiation 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MYOD1 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of MYOD1 mRNA CTD PMID:16931933 NCBI chr 1:106,021,161...106,023,871
Ensembl chr 1:106,021,161...106,023,871
JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NAP1L5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NAP1L5 mRNA CTD PMID:16931933 NCBI chr 4:89,352,834...89,354,704
Ensembl chr 4:89,351,926...89,361,736
JBrowse link
G Ndufa4 Ndufa4, mitochondrial complex associated multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFA4 mRNA CTD PMID:18313992 NCBI chr 4:40,968,391...40,975,559
Ensembl chr 4:40,968,391...40,975,559
JBrowse link
G Ndufab1 NADH:ubiquinone oxidoreductase subunit AB1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAB1 mRNA CTD PMID:18313992 NCBI chr 1:186,075,933...186,091,843
Ensembl chr 1:186,057,113...186,089,373
JBrowse link
G Ndufaf1 NADH:ubiquinone oxidoreductase complex assembly factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFAF1 mRNA CTD PMID:18313992 NCBI chr 3:127,089,893...127,104,357
Ensembl chr 3:127,093,659...127,104,020
JBrowse link
G Ndufb3 NADH:ubiquinone oxidoreductase subunit B3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB3 mRNA CTD PMID:18313992 NCBI chr 9:67,623,417...67,633,629
Ensembl chr 9:67,623,614...67,633,613
JBrowse link
G Ndufb5 NADH:ubiquinone oxidoreductase subunit B5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of NDUFB5 mRNA CTD PMID:18313992 NCBI chr 2:117,447,605...117,461,943
Ensembl chr 2:117,447,035...117,461,590
JBrowse link
G Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFB9 mRNA CTD PMID:18313992 NCBI chr 7:92,370,423...92,376,841
Ensembl chr 7:92,370,467...92,379,955
JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFC1 mRNA CTD PMID:18313992 NCBI chr 2:137,597,944...137,601,819
Ensembl chr 2:137,600,156...137,601,735
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NDUFS1 mRNA CTD PMID:18313992 NCBI chr 9:72,040,286...72,073,605
Ensembl chr 9:72,040,090...72,073,605
JBrowse link
G Niban1 niban apoptosis regulator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NIBAN1 mRNA CTD PMID:15784690 NCBI chr13:66,224,219...66,377,728
Ensembl chr13:66,224,021...66,377,724
JBrowse link
G Noct nocturnin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of NOCT mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of NOCT mRNA CTD PMID:16931933 NCBI chr 2:137,422,074...137,442,282
Ensembl chr 2:137,422,074...137,442,282
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
decreases phosphorylation
ISO coenzyme Q10 inhibits the reaction [Lamivudine results in decreased phosphorylation of NOS3 protein] CTD PMID:23640862 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
JBrowse link
G Nppa natriuretic peptide A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NPPA mRNA CTD PMID:11706060 NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:163,712,184...163,713,493
JBrowse link
G Nup210 nucleoporin 210 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NUP210 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of NUP210 mRNA CTD PMID:16931933 NCBI chr 4:125,068,736...125,167,238
Ensembl chr 4:125,068,736...125,167,047
JBrowse link
G Nxnl2 nucleoredoxin-like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of NXNL2 mRNA CTD PMID:16931933 NCBI chr17:14,182,849...14,187,595
Ensembl chr17:14,182,849...14,188,208
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of OAZ3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of OAZ3 mRNA CTD PMID:16931933 NCBI chr 2:184,762,242...184,765,176
Ensembl chr 2:184,762,245...184,771,428
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OGT mRNA CTD PMID:15784690 NCBI chr  X:70,811,317...70,856,123
Ensembl chr  X:70,811,319...70,856,123
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPA1 mRNA CTD PMID:18313992 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of OPRL1 mRNA CTD PMID:16931933 NCBI chr 3:189,209,495...189,225,406
Ensembl chr 3:189,212,175...189,217,426
JBrowse link
G Pcdh15 protocadherin related 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PCDH15 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PCDH15 mRNA CTD PMID:16931933 NCBI chr20:13,996,383...15,495,206
Ensembl chr20:13,999,116...15,493,958
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PCK2 mRNA CTD PMID:15784690 NCBI chr15:32,997,853...33,006,691
Ensembl chr15:32,997,834...33,016,864
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PFKFB3 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PFKFB3 mRNA CTD PMID:16931933 NCBI chr17:71,893,320...71,974,526
Ensembl chr17:71,893,416...71,975,052
JBrowse link
G Pgap6 post-GPI attachment to proteins 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PGAP6 mRNA CTD PMID:16931933 NCBI chr10:15,643,081...15,652,912
Ensembl chr10:15,643,106...15,652,912
JBrowse link
G Phf6 PHD finger protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of PHF6 mRNA CTD PMID:16931933 NCBI chr  X:137,576,214...137,619,297
Ensembl chr  X:137,576,235...137,615,914
JBrowse link
G Pidd1 p53-induced death domain protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIDD1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIDD1 mRNA CTD PMID:16931933 NCBI chr 1:205,966,392...205,972,359
Ensembl chr 1:205,966,392...205,971,600
JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIWIL2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of PIWIL2 mRNA CTD PMID:16931933 NCBI chr15:51,841,104...51,907,729
Ensembl chr15:51,841,405...51,907,819
JBrowse link
G Porcn porcupine O-acyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PPN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PPN mRNA CTD PMID:16931933 NCBI chr  X:16,957,811...16,970,440
Ensembl chr  X:16,957,810...16,970,439
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of POU5F1 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of POU5F1 mRNA CTD PMID:16931933 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,227,837...3,232,598
JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of PRDM1 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PRDM1 mRNA CTD PMID:16931933 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:49,542,465...49,564,088
JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of PSAT1 mRNA CTD PMID:15784690 NCBI chr 1:222,623,553...222,646,187
Ensembl chr 1:222,623,556...222,655,693
JBrowse link
G Rabepk Rab9 effector protein with kelch motifs multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RABEPK mRNA CTD PMID:15784690 NCBI chr 3:38,460,205...38,481,077
Ensembl chr 3:38,460,206...38,480,688
JBrowse link
G Rbl1 RB transcriptional corepressor like 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL1 mRNA CTD PMID:15784690 NCBI chr 3:166,226,187...166,289,862
Ensembl chr 3:166,226,198...166,289,376
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of RBL2 mRNA CTD PMID:15784690 NCBI chr19:32,049,690...32,096,467
Ensembl chr19:32,049,691...32,096,411
JBrowse link
G Reep6 receptor accessory protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of REEP6 mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of REEP6 mRNA CTD PMID:16931933 NCBI chr 7:10,024,601...10,031,507
Ensembl chr 7:10,024,602...10,031,740
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of RIPK2 mRNA CTD PMID:15784690 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663
JBrowse link
G Rnf151 ring finger protein 151 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of RNF151 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of RNF151 mRNA CTD PMID:16931933 NCBI chr10:14,247,215...14,251,738
Ensembl chr10:14,247,215...14,251,204
JBrowse link
G Rpain RPA interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of RPAIN mRNA; [Zidovudine co-treated with Lamivudine] results in decreased expression of RPAIN mRNA CTD PMID:16931933 NCBI chr10:56,190,975...56,198,490
Ensembl chr10:56,190,967...56,199,685
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in decreased expression of S100A8 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of S100A8 mRNA CTD PMID:16931933 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:178,464,702...178,465,221
JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SDHB mRNA CTD PMID:18313992 NCBI chr 5:158,547,775...158,568,589
Ensembl chr 5:158,547,689...158,569,667
JBrowse link
G Serinc1 serine incorporator 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SERINC1 mRNA CTD PMID:16931933 NCBI chr20:37,396,497...37,415,433
Ensembl chr20:37,396,497...37,443,124
JBrowse link
G Sfxn1 sideroflexin 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN1 mRNA CTD PMID:18313992 NCBI chr17:10,491,315...10,527,793
Ensembl chr17:10,491,344...10,527,456
JBrowse link
G Sfxn2 sideroflexin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN2 mRNA CTD PMID:18313992 NCBI chr 1:255,388,428...255,400,724
Ensembl chr 1:255,388,429...255,409,780
JBrowse link
G Sfxn4 sideroflexin 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SFXN4 mRNA CTD PMID:18313992 NCBI chr 1:269,962,527...269,984,849
Ensembl chr 1:269,962,535...269,984,836
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SGPP1 mRNA CTD PMID:18313992 NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:100,161,024...100,182,259
JBrowse link
G Slc1a4 solute carrier family 1 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A4 mRNA CTD PMID:15784690 NCBI chr14:98,718,646...98,761,672
Ensembl chr14:98,730,450...98,761,790
JBrowse link
G Slc1a5 solute carrier family 1 member 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC1A5 mRNA CTD PMID:15784690 NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:86,584,949...86,599,054
JBrowse link
G Slc22a1 solute carrier family 22 member 1 increases uptake ISO SLC22A1 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:50,624,339...50,651,437
Ensembl chr 1:50,624,377...50,651,436
JBrowse link
G Slc22a2 solute carrier family 22 member 2 increases uptake ISO SLC22A2 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:50,668,817...50,711,019
Ensembl chr 1:50,668,817...50,711,019
JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases uptake ISO SLC22A3 protein results in increased uptake of Lamivudine CTD PMID:19141712 NCBI chr 1:50,783,218...50,872,358
Ensembl chr 1:50,783,218...50,872,353
JBrowse link
G Slc25a12 solute carrier family 25 member 12 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A12 mRNA CTD PMID:18313992 NCBI chr 3:76,504,868...76,599,536
Ensembl chr 3:76,504,868...76,599,536
JBrowse link
G Slc25a15 solute carrier family 25 member 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A15 mRNA CTD PMID:18313992 NCBI chr16:76,334,037...76,357,325
Ensembl chr16:76,324,288...76,357,321
JBrowse link
G Slc25a19 solute carrier family 25 member 19 multiple interactions ISO SLC25A19 protein affects the susceptibility to [Stavudine co-treated with Lamivudine co-treated with Indinavir]; SLC25A19 protein affects the susceptibility to [Zidovudine co-treated with Lamivudine co-treated with Indinavir]
[Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A19 mRNA
CTD PMID:15951836 PMID:18313992 NCBI chr10:101,353,426...101,366,551
Ensembl chr10:101,350,106...101,366,351
JBrowse link
G Slc25a2 solute carrier family 25 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A2 mRNA CTD PMID:18313992 NCBI chr18:29,704,182...29,707,563
Ensembl chr18:29,703,871...29,708,827
JBrowse link
G Slc25a20 solute carrier family 25 member 20 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A20 mRNA CTD PMID:18313992 NCBI chr 8:118,243,573...118,265,027
Ensembl chr 8:118,243,519...118,265,027
JBrowse link
G Slc25a29 solute carrier family 25 member 29 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A29 mRNA CTD PMID:18313992 NCBI chr 6:133,506,403...133,517,322
Ensembl chr 6:133,506,331...133,517,827
JBrowse link
G Slc25a3 solute carrier family 25 member 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of SLC25A3 mRNA CTD PMID:18313992 NCBI chr 7:27,499,164...27,506,685
Ensembl chr 7:27,499,165...27,506,309
JBrowse link
G Slc25a4 solute carrier family 25 member 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC25A4 mRNA CTD PMID:18313992 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:52,805,523...52,811,700
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions ISO Lamivudine inhibits the reaction [SLC28A1 protein results in increased transport of Uridine] CTD PMID:10772724 NCBI chr 1:144,490,453...144,532,025
Ensembl chr 1:144,490,623...144,531,544
JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC31A1 mRNA CTD PMID:15784690 NCBI chr 5:80,830,574...80,859,810
Ensembl chr 5:80,830,389...80,859,809
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC3A2 mRNA CTD PMID:15784690 NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:215,033,601...215,048,064
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SLC40A1 mRNA CTD PMID:18313992 NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:55,525,532...55,543,460
JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases expression
ISO [Lamivudine co-treated with IFNA2 protein] results in increased expression of SLC6A4 mRNA; Lamivudine promotes the reaction [SLC6A4 protein results in increased uptake of Serotonin]; Lamivudine results in increased expression of and results in increased activity of SLC6A4 protein
Lamivudine results in increased expression of SLC6A4 mRNA
CTD PMID:16476009 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of SPINK5 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of SPINK5 mRNA CTD PMID:16931933 NCBI chr18:36,515,347...36,584,038
Ensembl chr18:36,515,347...36,583,799
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of STAR mRNA CTD PMID:18313992 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
JBrowse link
G Stc2 stanniocalcin 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of STC2 mRNA CTD PMID:15784690 NCBI chr10:16,755,508...16,765,275
Ensembl chr10:16,755,267...16,767,447
JBrowse link
G Sub1 SUB1 regulator of transcription multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of SUB1 mRNA CTD PMID:16931933 NCBI chr 2:62,735,379...62,747,545
Ensembl chr 2:62,732,736...62,747,679
JBrowse link
G Tcea1 transcription elongation factor A1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TCEA1 mRNA CTD PMID:15784690 NCBI chr 5:19,414,351...19,466,629
Ensembl chr15:12,831,339...12,834,156
Ensembl chr 5:12,831,339...12,834,156
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression ISO Lamivudine results in decreased expression of TGFB1 protein CTD PMID:15309715 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM17B mRNA CTD PMID:18313992 NCBI chr  X:17,268,257...17,275,424
Ensembl chr  X:17,268,257...17,275,563
JBrowse link
G Timm23 translocase of inner mitochondrial membrane 23 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TIMM23 mRNA CTD PMID:18313992 NCBI chr16:7,416,590...7,442,681
Ensembl chr16:7,416,597...7,442,658
Ensembl chr 3:7,416,597...7,442,658
Ensembl chr 6:7,416,597...7,442,658
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 decreases expression ISO Lamivudine results in decreased expression of TIMP1 protein CTD PMID:15309715 NCBI chr  X:3,766,509...3,772,578
Ensembl chr  X:3,766,510...3,771,135
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TIMP2 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TIMP2 mRNA CTD PMID:16931933 NCBI chr10:104,041,604...104,089,214
Ensembl chr10:104,041,604...104,089,214
JBrowse link
G Tk2 thymidine kinase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TK2 mRNA CTD PMID:18313992 NCBI chr19:713,043...737,345
Ensembl chr19:715,318...738,355
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of TNF protein; Zinc inhibits the reaction [[efavirenz co-treated with Lamivudine co-treated with Tenofovir] results in increased expression of TNF protein] CTD PMID:36309141 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Trib3 tribbles pseudokinase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of TRIB3 mRNA CTD PMID:15784690 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:161,269,955...161,274,802
JBrowse link
G Trim42 tripartite motif-containing 42 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TRIM42 mRNA; [Zidovudine co-treated with Lamivudine] results in increased expression of TRIM42 mRNA CTD PMID:16931933 NCBI chr 8:106,781,847...106,802,764
Ensembl chr 8:106,781,851...106,802,764
JBrowse link
G Twnk twinkle mtDNA helicase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TWNK mRNA CTD PMID:18313992 NCBI chr 1:253,817,074...253,823,958
Ensembl chr 1:253,817,564...253,824,162
JBrowse link
G Tyms thymidylate synthetase multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYMS mRNA CTD PMID:15784690 NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:120,763,386...120,776,097
JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of TYRP1 mRNA CTD PMID:15784690 NCBI chr 5:100,327,111...100,345,657
Ensembl chr 5:100,327,125...100,345,657
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRB mRNA CTD PMID:18313992 NCBI chr 7:65,700,016...65,705,382
Ensembl chr 7:65,700,029...65,705,558
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of UQCRC1 mRNA CTD PMID:17526437 PMID:18313992 NCBI chr 8:118,468,223...118,479,968
Ensembl chr 8:118,468,200...118,479,964
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of UQCRC2 mRNA CTD PMID:18313992 NCBI chr 1:184,599,240...184,629,804
Ensembl chr 1:184,599,212...184,630,946
JBrowse link
G Vdac1 voltage-dependent anion channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDAC1 mRNA CTD PMID:18313992 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:37,023,145...37,060,541
JBrowse link
G Vdr vitamin D receptor multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VDR mRNA CTD PMID:11741158 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:130,866,745...130,916,757
JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in decreased expression of VPS4B mRNA CTD PMID:16931933 NCBI chr13:23,421,758...23,446,848
Ensembl chr13:23,421,758...23,446,973
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of WARS1 mRNA CTD PMID:15784690 NCBI chr 6:133,540,463...133,571,645
Ensembl chr 6:133,539,744...133,571,645
JBrowse link
G Wnt10a Wnt family member 10A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of WNT10A mRNA; [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of WNT10A mRNA CTD PMID:16931933 NCBI chr 9:83,798,594...83,811,060
Ensembl chr 9:83,798,594...83,811,067
JBrowse link
G Yars1 tyrosyl-tRNA synthetase 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine] results in increased expression of YARS1 mRNA CTD PMID:15784690 NCBI chr 5:146,820,163...146,848,377
Ensembl chr 5:146,819,358...146,848,377
JBrowse link
meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO tetra(4-N-methylpyridyl)porphine binds to and affects the folding of MYC gene CTD PMID:15740131 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
MST-312 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H2ax H2A.X variant histone increases expression ISO MST 312 results in increased expression of H2AX protein modified form CTD PMID:26022559 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
neobavaisoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D decreases activity ISO neobavaisoflavone results in decreased activity of CES1 protein CTD PMID:26560012 NCBI chr19:30,046,494...30,085,039
Ensembl chr19:30,046,449...30,085,449
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
EXP neobavaisoflavone inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]
neobavaisoflavone results in decreased activity of CYP2E1 protein
CTD PMID:31870919 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP neobavaisoflavone results in increased expression of CYP3A4 mRNA CTD PMID:31870919 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
pamidronate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adm adrenomedullin increases expression ISO Pamidronate results in increased expression of ADM mRNA CTD PMID:38447685 NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:174,178,773...174,182,371
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO pamidronate results in increased expression of ALPL protein CTD PMID:11683535 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO pamidronate results in decreased expression of B2M protein CTD PMID:11683535 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:129,549,318...129,555,356
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO pamidronate results in decreased expression of BCL2 protein CTD PMID:10780527 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO pamidronate results in increased expression of BGLAP protein CTD PMID:11683535 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
JBrowse link
G Bik BCL2-interacting killer increases response to substance ISO BIK protein results in increased susceptibility to pamidronate CTD PMID:16007125 NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:116,552,303...116,571,317
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO pamidronate results in increased cleavage of and results in increased activity of CASP3 protein
pamidronate results in increased cleavage of CASP3 protein
CTD PMID:15346059 PMID:16298452 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp9 caspase 9 increases cleavage ISO pamidronate results in increased cleavage of CASP9 protein CTD PMID:16298452 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO pamidronate results in decreased expression of COL1A1 mRNA; pamidronate results in decreased expression of COL1A1 protein CTD PMID:19597852 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Crp C-reactive protein decreases expression
increases expression
ISO pamidronate results in decreased expression of CRP protein
pamidronate results in increased expression of CRP protein
CTD PMID:9351880 PMID:11683535 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Pamidronate results in increased expression of CXCR4 mRNA CTD PMID:38447685 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Pamidronate results in increased expression of DUSP1 mRNA CTD PMID:38447685 NCBI chr10:17,184,853...17,187,646
Ensembl chr10:17,184,823...17,187,644
JBrowse link
G Egf epidermal growth factor multiple interactions ISO [Arsenic Trioxide co-treated with Pamidronate] promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Pamidronate promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:32337366 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Arsenic Trioxide co-treated with Pamidronate] promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]; Pamidronate promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:32337366 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Fdps farnesyl diphosphate synthase decreases activity ISO
EXP
pamidronate results in decreased activity of FDPS protein CTD PMID:11160603 PMID:18325729 NCBI chr 2:176,795,192...176,804,816
Ensembl chr 2:176,795,192...176,807,136
JBrowse link
G Fgf23 fibroblast growth factor 23 decreases expression ISO pamidronate results in decreased expression of FGF23 protein CTD PMID:15838626 NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:161,600,383...161,609,991
JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Pamidronate results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine] which results in increased secretion of IL18 protein CTD PMID:21282739 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286
JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions
ISO Pamidronate results in increased secretion of IL1B protein
[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein; [Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein; geraniol inhibits the reaction [[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; Pamidronate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]
CTD PMID:21282739 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 decreases expression
increases expression
ISO pamidronate results in decreased expression of IL6 protein
pamidronate results in increased expression of IL6 protein
CTD PMID:9351880 PMID:11683535 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Klhdc2 kelch domain containing 2 decreases expression ISO Pamidronate results in decreased expression of KLHDC2 mRNA CTD PMID:38447685 NCBI chr 6:93,512,981...93,552,809
Ensembl chr 6:93,513,017...93,577,762
JBrowse link
G Ldha lactate dehydrogenase A increases expression ISO Pamidronate results in increased expression of LDHA mRNA CTD PMID:38447685 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Pamidronate results in increased expression of MAFF mRNA CTD PMID:38447685 NCBI chr 7:112,792,787...112,804,139
Ensembl chr 7:112,791,416...112,804,147
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases expression ISO pamidronate results in decreased expression of MAPK1 protein modified form CTD PMID:16298452 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Pamidronate results in increased expression of MSMO1 mRNA CTD PMID:38447685 NCBI chr16:29,747,113...29,764,360
Ensembl chr16:29,747,137...29,764,445
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO pamidronate results in increased cleavage of PARP1 protein
[pamidronate co-treated with ultra-high molecular weight polyethylene] results in increased cleavage of PARP1 protein
CTD PMID:10780527 PMID:12507583 PMID:15346059 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pon1 paraoxonase 1 decreases activity
multiple interactions
EXP pamidronate results in decreased activity of PON1 protein
[pamidronate results in decreased activity of PON1 protein] which results in decreased metabolism of homocysteine thiolactone; [pamidronate results in decreased activity of PON1 protein] which results in decreased metabolism of Paraoxon; [pamidronate results in decreased activity of PON1 protein] which results in decreased metabolism of phenyl acetate
CTD PMID:27387541 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:34,261,289...34,287,924
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Pamidronate results in increased expression of PPP1R15A mRNA CTD PMID:38447685 NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:105,136,525...105,139,774
JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 multiple interactions ISO Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Pamidronate promotes the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]; Arsenic Trioxide promotes the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]; Pamidronate promotes the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]; Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein CTD PMID:32337366 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:177,057,659...177,106,416
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO pamidronate increases expression of RAC1 mRNA in cholangiocarcinoma cells, pamidronate decreases expression of RAC1 protein in cholangiocarcinoma cells RGD PMID:31611937 RGD:153345545 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases prenylation ISO pamidronate results in decreased prenylation of RAP1A protein CTD PMID:11595616 NCBI chr 2:195,896,967...195,974,851
Ensembl chr 2:195,896,971...195,974,808
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO pamidronate results in decreased expression of RHOA protein modified form CTD PMID:16298452 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression ISO pamidronate results in decreased expression of ROCK1 protein CTD PMID:16298452 NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,387,360...1,509,147
JBrowse link
G Sertad1 SERTA domain containing 1 increases expression ISO Pamidronate results in increased expression of SERTAD1 mRNA CTD PMID:38447685 NCBI chr 1:91,903,297...91,906,565
Ensembl chr 1:91,891,814...91,907,001
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO pamidronate results in increased expression of TNF protein
pamidronate inhibits the reaction [ultra-high molecular weight polyethylene results in increased secretion of TNF protein]
CTD PMID:9351880 PMID:12507583 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions
increases expression
ISO pamidronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; pamidronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]
pamidronate results in increased expression of TNFRSF11B mRNA; pamidronate results in increased expression of TNFRSF11B protein
CTD PMID:11855844 NCBI chr 7:87,456,318...87,484,324
Ensembl chr 7:87,456,319...87,485,075
JBrowse link
pyridoxal 5'-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases abundance ISO ALPL gene mutant form results in increased abundance of Pyridoxal Phosphate CTD PMID:7550313 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Pyridoxal Phosphate results in decreased expression of BCL2 protein CTD PMID:16690808 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Ddc dopa decarboxylase affects binding
multiple interactions
ISO Chlorpyrifos binds to [DDC protein binds to Pyridoxal Phosphate]; DDC protein binds to Pyridoxal Phosphate; Diazinon binds to [DDC protein binds to Pyridoxal Phosphate]; Glyphosate binds to [DDC protein binds to Pyridoxal Phosphate]; Isoflurophate binds to [DDC protein binds to Pyridoxal Phosphate]; Malathion binds to [DDC protein binds to Pyridoxal Phosphate]; mipafox binds to [DDC protein binds to Pyridoxal Phosphate]; novichok binds to [DDC protein binds to Pyridoxal Phosphate]; O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate binds to [DDC protein binds to Pyridoxal Phosphate]; Paraoxon binds to [DDC protein binds to Pyridoxal Phosphate]; phenyl di-n-pentylphosphinate binds to [DDC protein binds to Pyridoxal Phosphate]; phenylsaligenin cyclic phosphate binds to [DDC protein binds to Pyridoxal Phosphate]; S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolate binds to [DDC protein binds to Pyridoxal Phosphate]; Sarin binds to [DDC protein binds to Pyridoxal Phosphate]; Soman binds to [DDC protein binds to Pyridoxal Phosphate]; tabun binds to [DDC protein binds to Pyridoxal Phosphate]; VX-agent binds to [DDC protein binds to Pyridoxal Phosphate]
[DDC protein binds to Pyridoxal Phosphate] which binds to and results in increased metabolism of Levodopa
CTD PMID:35151785 NCBI chr14:90,592,304...90,682,830
Ensembl chr14:90,592,304...90,682,806
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Pyridoxal Phosphate inhibits the reaction [Acetaldehyde results in increased expression of FN1 mRNA] CTD PMID:8151099 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
JBrowse link
G Fut8 fucosyltransferase 8 multiple interactions
decreases activity
ISO Fucose analog inhibits the reaction [Pyridoxal Phosphate results in decreased activity of FUT8 protein] CTD PMID:12770769 NCBI chr 6:101,682,354...101,909,784
Ensembl chr 6:101,683,007...101,909,775
JBrowse link
G Gad1 glutamate decarboxylase 1 affects binding
multiple interactions
decreases activity
increases activity
ISO
EXP
Chlorpyrifos binds to [GAD1 protein binds to Pyridoxal Phosphate]; Diazinon binds to [GAD1 protein binds to Pyridoxal Phosphate]; GAD1 protein binds to Pyridoxal Phosphate; Glyphosate binds to [GAD1 protein binds to Pyridoxal Phosphate]; Isoflurophate binds to [GAD1 protein binds to Pyridoxal Phosphate]; Malathion binds to [GAD1 protein binds to Pyridoxal Phosphate]; mipafox binds to [GAD1 protein binds to Pyridoxal Phosphate]; novichok binds to [GAD1 protein binds to Pyridoxal Phosphate]; O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate binds to [GAD1 protein binds to Pyridoxal Phosphate]; Paraoxon binds to [GAD1 protein binds to Pyridoxal Phosphate]; phenyl di-n-pentylphosphinate binds to [GAD1 protein binds to Pyridoxal Phosphate]; phenylsaligenin cyclic phosphate binds to [GAD1 protein binds to Pyridoxal Phosphate]; Pyridoxal Phosphate binds to GAD1 protein modified form; S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolate binds to [GAD1 protein binds to Pyridoxal Phosphate]; Sarin binds to [GAD1 protein binds to Pyridoxal Phosphate]; Soman binds to [GAD1 protein binds to Pyridoxal Phosphate]; tabun binds to [GAD1 protein binds to Pyridoxal Phosphate]; VX-agent binds to [GAD1 protein binds to Pyridoxal Phosphate]
[GAD1 protein binds to Pyridoxal Phosphate] which binds to and results in increased metabolism of Glutamic Acid
Pyridoxal Phosphate results in decreased activity of GAD1 protein
Pyridoxal Phosphate results in increased activity of GAD1 protein
CTD PMID:171340 PMID:7463050 PMID:15686475 PMID:35151785 NCBI chr 3:75,777,260...75,818,099
Ensembl chr 3:75,777,534...75,818,759
JBrowse link
G Gad2 glutamate decarboxylase 2 affects binding
multiple interactions
ISO Chlorpyrifos binds to [GAD2 protein binds to Pyridoxal Phosphate]; Diazinon binds to [GAD2 protein binds to Pyridoxal Phosphate]; GAD2 protein binds to Pyridoxal Phosphate; Glyphosate binds to [GAD2 protein binds to Pyridoxal Phosphate]; Isoflurophate binds to [GAD2 protein binds to Pyridoxal Phosphate]; Malathion binds to [GAD2 protein binds to Pyridoxal Phosphate]; mipafox binds to [GAD2 protein binds to Pyridoxal Phosphate]; novichok binds to [GAD2 protein binds to Pyridoxal Phosphate]; O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate binds to [GAD2 protein binds to Pyridoxal Phosphate]; Paraoxon binds to [GAD2 protein binds to Pyridoxal Phosphate]; phenyl di-n-pentylphosphinate binds to [GAD2 protein binds to Pyridoxal Phosphate]; phenylsaligenin cyclic phosphate binds to [GAD2 protein binds to Pyridoxal Phosphate]; Pyridoxal Phosphate binds to GAD2 protein; Pyridoxal Phosphate binds to GAD2 protein modified form; S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolate binds to [GAD2 protein binds to Pyridoxal Phosphate]; Sarin binds to [GAD2 protein binds to Pyridoxal Phosphate]; Soman binds to [GAD2 protein binds to Pyridoxal Phosphate]; tabun binds to [GAD2 protein binds to Pyridoxal Phosphate]; VX-agent binds to [GAD2 protein binds to Pyridoxal Phosphate]
[GAD2 protein binds to Pyridoxal Phosphate] which binds to and results in increased metabolism of Glutamic Acid
CTD PMID:15686475 PMID:15690345 PMID:15836621 PMID:35151785 NCBI chr17:89,671,718...89,734,246
Ensembl chr17:89,671,716...89,941,089
JBrowse link
G Gh1 growth hormone 1 decreases secretion EXP Pyridoxal Phosphate results in decreased secretion of GH1 protein CTD PMID:16690808 NCBI chr10:91,727,883...91,729,860
Ensembl chr10:91,727,884...91,729,859
JBrowse link
G Hdc histidine decarboxylase multiple interactions
affects binding
ISO [HDC protein binds to Pyridoxal Phosphate] which binds to and results in increased metabolism of Histidine
Chlorpyrifos binds to [HDC protein binds to Pyridoxal Phosphate]; Diazinon binds to [HDC protein binds to Pyridoxal Phosphate]; Glyphosate binds to [HDC protein binds to Pyridoxal Phosphate]; HDC protein binds to Pyridoxal Phosphate; Isoflurophate binds to [HDC protein binds to Pyridoxal Phosphate]; Malathion binds to [HDC protein binds to Pyridoxal Phosphate]; mipafox binds to [HDC protein binds to Pyridoxal Phosphate]; novichok binds to [HDC protein binds to Pyridoxal Phosphate]; O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate binds to [HDC protein binds to Pyridoxal Phosphate]; Paraoxon binds to [HDC protein binds to Pyridoxal Phosphate]; phenyl di-n-pentylphosphinate binds to [HDC protein binds to Pyridoxal Phosphate]; phenylsaligenin cyclic phosphate binds to [HDC protein binds to Pyridoxal Phosphate]; S-(N,N-diethylaminoethyl) isobutyl methylphosphothiolate binds to [HDC protein binds to Pyridoxal Phosphate]; Sarin binds to [HDC protein binds to Pyridoxal Phosphate]; Soman binds to [HDC protein binds to Pyridoxal Phosphate]; tabun binds to [HDC protein binds to Pyridoxal Phosphate]; VX-agent binds to [HDC protein binds to Pyridoxal Phosphate]
CTD PMID:35151785 NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:134,300,632...134,318,711
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions ISO Pyridoxal Phosphate binds to and results in increased activity of NRIP1 protein CTD PMID:17277785 NCBI chr11:28,382,835...28,466,483
Ensembl chr11:28,378,878...28,467,353
JBrowse link
G Pdxk pyridoxal kinase decreases activity EXP Pyridoxal Phosphate results in decreased activity of PDXK protein CTD PMID:7463050 NCBI chr20:10,209,975...10,232,012
Ensembl chr20:10,209,832...10,233,780
JBrowse link
G Pomc proopiomelanocortin decreases secretion ISO Pyridoxal Phosphate results in decreased secretion of POMC protein CTD PMID:16690808 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:32,659,346...32,665,173
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP Pyridoxal Phosphate inhibits the reaction [Ethanol results in decreased activity of PPARA protein] CTD PMID:11022051 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Prl prolactin decreases secretion EXP Pyridoxal Phosphate results in decreased secretion of PRL protein CTD PMID:16690808 NCBI chr17:38,287,355...38,298,234
Ensembl chr17:38,288,162...38,298,217
JBrowse link
G Srr serine racemase multiple interactions ISO Pyridoxal Phosphate inhibits the reaction [Hydroxylamine inhibits the reaction [SRR protein results in increased abundance of D-Aspartic Acid]] CTD PMID:27387750 NCBI chr10:60,267,936...60,285,094
Ensembl chr10:60,268,859...60,285,100
JBrowse link
ribavirin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn2 actinin alpha 2 decreases expression ISO Ribavirin results in decreased expression of ACTN2 protein CTD PMID:32112805 NCBI chr17:62,835,055...62,902,331
Ensembl chr17:62,812,988...62,903,552
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Ribavirin results in decreased phosphorylation of AKT1 protein CTD PMID:29112301 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:137,535,390...137,552,610
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 multiple interactions
decreases expression
ISO Ribavirin inhibits the reaction [CARM1 protein binds to EIF4E promoter]; Ribavirin inhibits the reaction [CARM1 protein binds to VEGFA promoter]
Ribavirin results in decreased expression of CARM1 protein
CTD PMID:34919946 NCBI chr 8:28,373,370...28,418,056
Ensembl chr 8:28,373,362...28,418,056
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO Ribavirin results in increased activity of CASP3 protein
Ribavirin promotes the reaction [FAS protein results in increased activity of CASP3 protein]
CTD PMID:12760867 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Ribavirin promotes the reaction [FAS protein results in increased activity of CASP7 protein] CTD PMID:12760867 NCBI chr 1:265,442,647...265,481,938
Ensembl chr 1:265,442,676...265,482,512
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Ribavirin promotes the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:12760867 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Ribavirin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein] CTD PMID:36416909 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO Ribavirin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] CTD PMID:36416909 NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,948,889...68,950,439
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Ribavirin results in decreased expression of CCNA2 protein CTD PMID:33577917 NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:121,355,363...121,361,701
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Ribavirin results in decreased expression of CCND1 protein CTD PMID:29112301 PMID:33577917 NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:209,518,288...209,527,810
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Ribavirin results in decreased expression of CCNE1 protein CTD PMID:33577917 NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:99,918,674...99,927,822
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions
decreases expression
decreases phosphorylation
ISO Ribavirin inhibits the reaction [CARM1 protein binds to EIF4E promoter]; Ribavirin inhibits the reaction [Doxorubicin results in increased phosphorylation of EIF4E protein]
Ribavirin results in decreased expression of EIF4E mRNA; Ribavirin results in decreased expression of EIF4E protein
Ribavirin results in decreased phosphorylation of EIF4E protein
CTD PMID:29112301 PMID:33577917 PMID:34919946 NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:229,739,897...229,774,105
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation ISO Ribavirin results in decreased phosphorylation of EIF4EBP1 protein CTD PMID:29112301 NCBI chr16:71,495,457...71,508,845
Ensembl chr16:71,487,930...71,508,874
JBrowse link
G Epo erythropoietin multiple interactions
increases expression
ISO [peginterferon alfa-2b co-treated with Ribavirin] affects the expression of EPO protein; [Ribavirin co-treated with Interferons] results in increased expression of EPO protein
Ribavirin results in increased expression of EPO
CTD PMID:12713065 PMID:15232364 PMID:20009130 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:24,841,285...24,844,725
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Ribavirin promotes the reaction [FAS protein results in increased activity of CASP3 protein]; Ribavirin promotes the reaction [FAS protein results in increased activity of CASP7 protein]; Ribavirin promotes the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:12760867 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104
JBrowse link
G Gas5 growth arrest specific 5 increases expression ISO Ribavirin results in increased expression of GAS5 mRNA CTD PMID:32112805 NCBI chr13:75,836,963...75,840,284 JBrowse link
G Gata4 GATA binding protein 4 decreases expression ISO Ribavirin results in decreased expression of GATA4 mRNA CTD PMID:32112805 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:41,635,572...41,681,609
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Ribavirin results in increased expression of H2AX protein modified form CTD PMID:32112805 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression ISO Ribavirin results in decreased expression of ICAM1 protein modified form CTD PMID:12853993 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
decreases expression
ISO [Ribavirin co-treated with IFNA2 protein] affects the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Ribavirin inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]; Ribavirin results in increased expression of and results in increased secretion of IFNG protein
Ribavirin results in increased expression of IFNG protein
Ribavirin results in increased expression of IFNG mRNA; Ribavirin results in increased expression of IFNG protein
Ribavirin results in decreased expression of IFNG mRNA
CTD PMID:9722937 PMID:10190717 PMID:10770762 PMID:17210188 PMID:29594315 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Ifnl3 interferon, lambda 3 multiple interactions ISO IFNL3 gene polymorphism affects the susceptibility to [Ribavirin co-treated with IFNA2 protein modified form]; IFNL3 gene SNP affects the susceptibility to [peginterferon alfa-2a co-treated with Ribavirin]; IFNL3 protein results in increased susceptibility to [Ribavirin co-treated with IFNA2 protein modified form] CTD PMID:19749757 PMID:19749758 PMID:22003405 NCBI chr 1:92,941,988...92,943,628 JBrowse link
G Il10 interleukin 10 multiple interactions
decreases expression
ISO
EXP
[Ribavirin co-treated with IFNA2 protein] affects the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; Ribavirin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL10 protein]; Ribavirin results in decreased expression of and results in decreased secretion of IL10 protein
[peginterferon alfa-2a co-treated with Ribavirin co-treated with Danazol] results in decreased expression of IL10 mRNA; [peginterferon alfa-2a co-treated with Ribavirin] results in increased expression of IL10 mRNA
Ribavirin results in decreased expression of IL10 protein
Ribavirin results in decreased expression of IL10 mRNA
CTD PMID:9722937 PMID:10190717 PMID:10770762 PMID:17210188 PMID:18007553 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il12a interleukin 12A multiple interactions ISO [Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]; Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:9722937 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997
JBrowse link
G Il12b interleukin 12B multiple interactions ISO [Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]]; Ribavirin promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein]; Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:9722937 PMID:36416909 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:29,389,905...29,405,194
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO Ribavirin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
Ribavirin results in increased expression of IL1B mRNA
CTD PMID:9722937 PMID:29594315 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression
ISO [Ribavirin co-treated with IFNA2 protein] promotes the reaction [Lipopolysaccharides results in increased secretion of IL2 protein]; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of IL2 protein]; Ribavirin results in increased expression of and results in increased secretion of IL2 protein
Ribavirin results in increased expression of IL2 mRNA; Ribavirin results in increased expression of IL2 protein
CTD PMID:9722937 PMID:10190717 PMID:10770762 PMID:29594315 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672
JBrowse link
G Il4 interleukin 4 decreases expression
multiple interactions
ISO Ribavirin results in decreased expression of IL4 mRNA; Ribavirin results in decreased expression of IL4 protein
Ribavirin promotes the reaction [Lipopolysaccharides results in increased secretion of IL4 protein]; Ribavirin results in decreased expression of and results in decreased secretion of IL4 protein
CTD PMID:9722937 PMID:10190717 PMID:10770762 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
JBrowse link
G Il5 interleukin 5 decreases expression
multiple interactions
ISO Ribavirin results in decreased expression of IL5 mRNA; Ribavirin results in decreased expression of IL5 protein
Ribavirin results in decreased expression of and results in decreased secretion of IL5 protein
CTD PMID:10190717 PMID:10770762 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [peginterferon alfa-2a co-treated with Ribavirin co-treated with Danazol] results in decreased expression of IL6 mRNA CTD PMID:18007553 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Isl1 ISL LIM homeobox 1 decreases expression ISO Ribavirin results in decreased expression of ISL1 mRNA CTD PMID:32112805 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:49,813,618...49,823,442
JBrowse link
G Itpa inosine triphosphatase increases response to substance ISO ITPA 5' UTR SNP results in increased susceptibility to Ribavirin CTD PMID:20637204 NCBI chr 3:138,338,549...138,350,329
Ensembl chr 3:138,338,349...138,350,329
JBrowse link
G Klrc1 killer cell lectin like receptor C1 affects expression ISO Ribavirin co-treated with Interferon alfa-2a affects expression of KLRC1 protein in Natural Killer cells RGD PMID:20550548 RGD:40818079 NCBI chr 4:164,828,163...164,838,446
Ensembl chr 4:164,828,163...164,838,464
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO Ribavirin results in decreased phosphorylation of MTOR protein CTD PMID:29112301 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:164,167,928...164,277,435
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Ribavirin results in decreased expression of MYC protein CTD PMID:29112301 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression ISO Ribavirin results in decreased expression of MYH6 mRNA CTD PMID:32112805 NCBI chr15:32,388,102...32,413,663
Ensembl chr15:32,387,487...32,411,333
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A multiple interactions ISO [Ribavirin co-treated with IFNA2 protein] results in increased activity of OAS1 protein CTD PMID:9722937 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO Ribavirin results in decreased expression of PCNA protein CTD PMID:33577917 PMID:34919946 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Prmt1 protein arginine methyltransferase 1 affects expression ISO Ribavirin affects the expression of PRMT1 protein CTD PMID:34919946 NCBI chr 1:104,595,339...104,605,552
Ensembl chr 1:104,595,335...104,604,827
JBrowse link
G Prmt2 protein arginine methyltransferase 2 decreases expression ISO Ribavirin results in decreased expression of PRMT2 protein CTD PMID:34919946 NCBI chr20:12,391,388...12,420,096
Ensembl chr20:12,394,268...12,420,108
JBrowse link
G Prmt3 protein arginine methyltransferase 3 decreases expression ISO Ribavirin results in decreased expression of PRMT3 protein CTD PMID:34919946 NCBI chr 1:108,628,899...108,718,803
Ensembl chr 1:108,626,749...108,718,803
JBrowse link
G Prmt5 protein arginine methyltransferase 5 decreases expression ISO Ribavirin results in decreased expression of PRMT5 protein CTD PMID:33577917 PMID:34919946 NCBI chr15:31,938,927...31,948,318
Ensembl chr15:31,938,719...31,948,426
JBrowse link
G Prmt6 protein arginine methyltransferase 6 affects expression ISO Ribavirin affects the expression of PRMT6 protein CTD PMID:34919946 NCBI chr 2:200,615,780...200,620,790
Ensembl chr 2:200,614,979...200,623,308
JBrowse link
G Prmt7 protein arginine methyltransferase 7 decreases expression ISO Ribavirin results in decreased expression of PRMT7 protein CTD PMID:33577917 PMID:34919946 NCBI chr19:51,020,596...51,071,401
Ensembl chr19:51,020,512...51,072,424
JBrowse link
G Prmt8 protein arginine methyltransferase 8 decreases expression ISO Ribavirin results in decreased expression of PRMT8 protein CTD PMID:34919946 NCBI chr 4:162,221,986...162,304,036
Ensembl chr 4:162,221,986...162,307,310
JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases uptake ISO SLC29A1 protein results in increased uptake of Ribavirin CTD PMID:20185188 NCBI chr 9:22,897,099...22,911,640
Ensembl chr 9:22,902,471...22,914,620
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Ribavirin CTD PMID:19164483 NCBI chr20:29,191,086...29,228,299
Ensembl chr20:29,191,127...29,228,299
JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases expression
ISO Ribavirin promotes the reaction [SLC6A4 protein results in increased uptake of Serotonin]; Ribavirin results in increased expression of and results in increased activity of SLC6A4 protein
Ribavirin results in increased expression of SLC6A4 mRNA
CTD PMID:16476009 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:62,324,254...62,357,056
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
Ribavirin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Ribavirin results in increased expression of and results in increased secretion of TNF protein
[peginterferon alfa-2a co-treated with Ribavirin co-treated with Danazol] results in decreased expression of TNF mRNA
Ribavirin results in increased expression of TNF mRNA; Ribavirin results in increased expression of TNF protein
CTD PMID:9722937 PMID:10190717 PMID:10770762 PMID:18007553 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases response to substance ISO Ribavirin results in decreased susceptibility to TNFSF10 protein CTD PMID:12637521 NCBI chr 2:112,136,550...112,155,903 JBrowse link
G Tnnt2 troponin T2, cardiac type decreases expression ISO Ribavirin results in decreased expression of TNNT2 protein CTD PMID:32112805 NCBI chr13:49,819,123...49,837,125
Ensembl chr13:49,822,304...49,837,125
JBrowse link
G Tp53 tumor protein p53 increases expression
affects activity
ISO Ribavirin results in increased expression of TP53 protein
Ribavirin affects the activity of TP53 protein
Ribavirin results in increased expression of TRP53 protein
CTD PMID:32112805 PMID:33577917 PMID:35435491 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Txn1 thioredoxin 1 decreases expression ISO Ribavirin results in decreased expression of TXN protein CTD PMID:16198661 NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:77,507,321...77,520,307
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
decreases secretion
multiple interactions
ISO Ribavirin results in decreased expression of VEGFA mRNA; Ribavirin results in decreased expression of VEGFA protein
Ribavirin results in decreased secretion of VEGFA protein
Ribavirin inhibits the reaction [CARM1 protein binds to VEGFA promoter]
CTD PMID:29112301 PMID:34919946 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
sodium aurothiomalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ACKR3 mRNA CTD PMID:19192274 NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:98,246,605...98,260,214
JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ADORA2A mRNA CTD PMID:19192274 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,270...13,332,802
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of AMIGO2 mRNA CTD PMID:19192274 NCBI chr 7:130,270,639...130,273,735
Ensembl chr 7:130,270,554...130,282,218
JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of ANTXR1 mRNA CTD PMID:19192274 NCBI chr 4:121,148,102...121,335,549
Ensembl chr 4:121,148,103...121,336,892
JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of AOX1 mRNA CTD PMID:19192274 NCBI chr 9:67,073,831...67,152,980
Ensembl chr 9:67,073,821...67,152,980
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of BCL2A1 mRNA CTD PMID:19192274 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:98,596,650...98,604,890
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of BST2 mRNA CTD PMID:19192274 NCBI chr16:18,250,593...18,254,967
Ensembl chr16:18,251,847...18,254,967
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CCL20 mRNA; Gold Sodium Thiomalate results in decreased expression of CCL20 protein CTD PMID:19192274 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:91,836,946...91,839,736
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of CCN1 mRNA CTD PMID:19192274 NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:237,222,432...237,225,883
JBrowse link
G Ccn5 cellular communication network factor 5 increases expression ISO Gold Sodium Thiomalate results in increased expression of CCN5 mRNA CTD PMID:19192274 NCBI chr 3:172,910,670...172,922,064
Ensembl chr 3:172,910,681...172,922,062
JBrowse link
G Cd28 Cd28 molecule multiple interactions
affects response to substance
ISO CD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CD28 protein affects the susceptibility to Gold Sodium Thiomalate
CTD PMID:19077085 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:252,908,749...252,944,273
JBrowse link
G Clgn calmegin decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CLGN mRNA CTD PMID:19192274 NCBI chr19:41,601,568...41,633,207
Ensembl chr19:41,601,568...41,633,325
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Gold Sodium Thiomalate results in increased expression of COL1A1 mRNA CTD PMID:19192274 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Colec12 collectin sub-family member 12 increases expression ISO Gold Sodium Thiomalate results in increased expression of COLEC12 mRNA CTD PMID:19192274 NCBI chr18:1,005,787...1,193,455
Ensembl chr18:1,005,741...1,195,297
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL1 mRNA CTD PMID:19192274 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,477,549...17,479,811
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL2 mRNA CTD PMID:19192274 NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,465,242...17,467,255
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL1 mRNA CTD PMID:19192274 NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,571,900...17,573,624
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCR4 mRNA CTD PMID:19192274 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:42,630,104...42,634,459
JBrowse link
G Ddx10 DEAD-box helicase 10 increases expression ISO Gold Sodium Thiomalate results in increased expression of DDX10 mRNA CTD PMID:19192274 NCBI chr 8:62,384,876...62,539,585
Ensembl chr 8:62,384,876...62,539,585
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Gold Sodium Thiomalate results in decreased activity of DIO1 protein CTD PMID:34662569 NCBI chr 5:127,303,089...127,319,784
Ensembl chr 5:127,303,083...127,319,771
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of EFEMP1 mRNA CTD PMID:19192274 NCBI chr14:106,811,769...106,890,961
Ensembl chr14:106,802,304...106,892,808
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of ENPP2 mRNA CTD PMID:19192274 NCBI chr 7:88,092,140...88,214,758
Ensembl chr 7:88,092,140...88,214,957
JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 increases expression ISO Gold Sodium Thiomalate results in increased expression of ENTPD3 mRNA CTD PMID:19192274 NCBI chr 8:129,124,540...129,155,528
Ensembl chr 8:129,124,709...129,156,252
JBrowse link
G Fbl fibrillarin affects localization
decreases activity
multiple interactions
ISO Gold Sodium Thiomalate affects the localization of FBL protein
Gold Sodium Thiomalate results in decreased activity of FBL protein
CD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CTD PMID:10942594 PMID:19077085 NCBI chr 1:92,597,407...92,606,507
Ensembl chr 1:92,597,258...92,606,506
JBrowse link
G Fbln1 fibulin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of FBLN1 mRNA CTD PMID:19192274 NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:118,190,478...118,269,965
JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression ISO Gold Sodium Thiomalate results in increased expression of FGF7 mRNA CTD PMID:19192274 NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:133,734,673...133,786,328
JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of GBP1 mRNA CTD PMID:19192274 NCBI chr 2:234,071,366...234,106,012
Ensembl chr 2:234,190,708...234,206,802
Ensembl chr 2:234,190,708...234,206,802
JBrowse link
G Gpm6b glycoprotein m6b increases expression ISO Gold Sodium Thiomalate results in increased expression of GPM6B mRNA CTD PMID:19192274 NCBI chr  X:31,689,485...31,836,199
Ensembl chr  X:31,690,359...31,733,272
JBrowse link
G Gsdme gasdermin E decreases expression ISO Gold Sodium Thiomalate results in decreased expression of GSDME mRNA CTD PMID:19192274 NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:80,588,614...80,641,525
JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HERC6 mRNA CTD PMID:19192274 NCBI chr 4:88,854,612...88,897,043
Ensembl chr 4:88,854,640...88,896,993
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HILPDA mRNA CTD PMID:19192274 NCBI chr 4:58,836,463...58,839,423
Ensembl chr 4:58,836,463...58,839,423
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:107,257,239...107,327,432
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI27 mRNA CTD PMID:19192274 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:128,355,079...128,361,781
JBrowse link
G Ifi35 interferon-induced protein 35 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI35 mRNA CTD PMID:19192274 NCBI chr10:86,881,270...86,889,523
Ensembl chr10:86,887,122...86,889,750
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI44 mRNA CTD PMID:19192274 NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:243,286,052...243,306,877
JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI44L mRNA CTD PMID:19192274 NCBI chr 2:243,328,629...243,366,404
Ensembl chr 2:243,328,723...243,366,404
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFIH1 mRNA CTD PMID:19192274 NCBI chr 3:67,635,924...67,683,968
Ensembl chr 3:67,637,545...67,683,968
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFIT3 mRNA CTD PMID:19192274 NCBI chr 1:241,527,326...241,532,469
Ensembl chr 1:241,526,880...241,532,521
JBrowse link
G Ifng interferon gamma multiple interactions
affects response to substance
ISO IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
IFNG protein affects the susceptibility to Gold Sodium Thiomalate
CTD PMID:19077085 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:10820281 NCBI chr16:76,021,968...76,075,717
Ensembl chr16:76,022,008...76,081,911
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL10 protein CTD PMID:11824965 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [[IL1B protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; Gold Sodium Thiomalate inhibits the reaction [IL1B protein results in increased expression of PTGES] CTD PMID:16393772 PMID:25314295 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IL1RN mRNA CTD PMID:19192274 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:27,509,798...27,525,732
JBrowse link
G Il23a interleukin 23 subunit alpha decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IL23A mRNA CTD PMID:19192274 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434
JBrowse link
G Il4 interleukin 4 multiple interactions
affects response to substance
ISO IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
IL4 protein affects the susceptibility to Gold Sodium Thiomalate
CTD PMID:19077085 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
affects response to substance
ISO [Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL6 protein
Gold Sodium Thiomalate results in decreased expression of IL6 mRNA; Gold Sodium Thiomalate results in decreased expression of IL6 protein
IL6 protein affects the susceptibility to Gold Sodium Thiomalate
IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CTD PMID:11824965 PMID:19077085 PMID:19192274 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IRF7 mRNA CTD PMID:19192274 NCBI chr 1:205,796,956...205,800,543
Ensembl chr 1:205,796,959...205,800,023
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ISG15 mRNA CTD PMID:19192274 NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:172,066,369...172,067,656
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ISG20 mRNA CTD PMID:19192274 NCBI chr 1:142,234,729...142,246,403
Ensembl chr 1:142,236,137...142,246,401
JBrowse link
G Lamb3 laminin subunit beta 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of LAMB3 mRNA CTD PMID:19192274 NCBI chr13:107,362,514...107,404,081
Ensembl chr13:107,322,526...107,404,081
JBrowse link
G Lxn latexin increases expression ISO Gold Sodium Thiomalate results in increased expression of LXN mRNA CTD PMID:19192274 NCBI chr 2:154,037,604...154,043,473
Ensembl chr 2:154,037,292...154,043,488
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO Gold Sodium Thiomalate results in decreased expression of LY6E mRNA CTD PMID:19192274 NCBI chr 7:108,815,970...108,820,444
Ensembl chr 7:108,816,887...108,820,443
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MARCKS mRNA CTD PMID:19192274 NCBI chr20:42,240,185...42,245,882
Ensembl chr20:42,240,185...42,245,882
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MET mRNA CTD PMID:19192274 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
JBrowse link
G Mir99b microRNA 99b multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased expression of MIR99B mRNA] CTD PMID:33109608 NCBI chr 1:67,350,064...67,350,133
Ensembl chr 1:67,350,060...67,350,139
JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MMP10 mRNA CTD PMID:19192274 NCBI chr 8:12,974,707...12,982,613
Ensembl chr 8:12,974,707...12,982,613
JBrowse link
G Mx1 MX dynamin like GTPase 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MX1 mRNA CTD PMID:19192274 NCBI chr11:50,269,056...50,294,699
Ensembl chr11:50,269,057...50,292,904
JBrowse link
G Ndufa4l2 NDUFA4, mitochondrial complex associated like 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of COXFA4L2 mRNA CTD PMID:19192274 NCBI chr 7:65,242,169...65,244,296
Ensembl chr 7:65,242,135...65,244,277
JBrowse link
G Nmb neuromedin B decreases expression ISO Gold Sodium Thiomalate results in decreased expression of NMB mRNA CTD PMID:19192274 NCBI chr 1:144,278,678...144,290,523
Ensembl chr 1:144,278,453...144,281,422
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [[IL1B protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide] CTD PMID:16393772 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:64,313,335...64,401,880
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of NR4A3 mRNA CTD PMID:19192274 NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:67,157,375...67,198,285
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO Gold Sodium Thiomalate results in decreased expression of OAS1 mRNA CTD PMID:19192274 NCBI chr12:41,330,423...41,341,130
Ensembl chr12:41,285,211...41,341,128
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression ISO Gold Sodium Thiomalate results in decreased expression of OASL mRNA CTD PMID:19192274 NCBI chr12:47,343,551...47,356,509
Ensembl chr12:47,343,551...47,356,483
JBrowse link
G Olfml2b olfactomedin-like 2B increases expression ISO Gold Sodium Thiomalate results in increased expression of OLFML2B mRNA CTD PMID:19192274 NCBI chr13:85,402,151...85,439,342
Ensembl chr13:85,402,169...85,439,342
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PHGDH mRNA CTD PMID:19192274 NCBI chr 2:188,595,700...188,624,789
Ensembl chr 2:188,595,700...188,624,789
JBrowse link
G Plpp3 phospholipid phosphatase 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PLPP3 mRNA CTD PMID:19192274 NCBI chr 5:125,156,000...125,231,119
Ensembl chr 5:125,155,945...125,235,667
JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of PPP4R2 mRNA CTD PMID:19192274 NCBI chr 4:135,010,919...135,051,844
Ensembl chr 4:135,010,919...135,051,844
JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [IL1B protein results in increased expression of PTGES] CTD PMID:25314295 NCBI chr 3:34,575,643...34,586,987
Ensembl chr 3:34,575,639...34,586,995
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PTGS2 mRNA CTD PMID:19192274 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of RARRES1 mRNA CTD PMID:19192274 NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:154,059,761...154,094,024
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein] CTD PMID:33109608 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RGS4 mRNA CTD PMID:19192274 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:84,469,593...84,475,884
JBrowse link
G Rig1 RNA sensor RIG-1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RIGI mRNA CTD PMID:19192274 NCBI chr 5:60,117,398...60,165,995
Ensembl chr 5:60,117,398...60,165,995
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RIPK2 mRNA CTD PMID:19192274 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663
JBrowse link
G Rnf19b ring finger protein 19B decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RNF19B mRNA CTD PMID:19192274 NCBI chr 5:146,690,453...146,715,729
Ensembl chr 5:146,690,577...146,714,394
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RSAD2 mRNA CTD PMID:19192274 NCBI chr 6:48,774,985...48,788,245
Ensembl chr 6:48,774,985...48,788,320
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:136,532,246...136,695,695
JBrowse link
G Sms spermine synthase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SMS mRNA CTD PMID:19192274 NCBI chr  X:41,331,693...41,387,713
Ensembl chr  X:41,331,799...41,387,712
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SOD2 mRNA CTD PMID:19192274 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:50,043,325...50,050,168
JBrowse link
G Spon1 spondin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of SPON1 mRNA CTD PMID:19192274 NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:177,363,197...177,662,676
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of STAT1 mRNA CTD PMID:19192274 NCBI chr 9:56,911,522...56,951,926
Ensembl chr 9:56,911,523...57,077,346
JBrowse link
G Sts steroid sulfatase increases expression ISO Gold Sodium Thiomalate results in increased expression of STS mRNA CTD PMID:19192274 NCBI chr  X:46,102,524...46,110,868
Ensembl chr  X:46,102,548...46,111,104
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of THBS1 mRNA CTD PMID:19192274 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:125,510,250...125,525,402
JBrowse link
G Thbs2 thrombospondin 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of THBS2 mRNA CTD PMID:19192274 NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:64,343,523...64,372,918
JBrowse link
G Tlr2 toll-like receptor 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of TLR2 mRNA CTD PMID:19192274 NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:171,497,060...171,520,194
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of TNFAIP2 mRNA CTD PMID:19192274 NCBI chr 6:136,297,388...136,311,106
Ensembl chr 6:136,298,082...136,311,106
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO Gold Sodium Thiomalate results in increased expression of TXNIP mRNA CTD PMID:19192274 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:186,781,163...186,785,731
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
decreases activity
ISO
EXP
Gold Sodium Thiomalate inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid]
Gold Sodium Thiomalate results in decreased activity of TXNRD1 protein
CTD PMID:16510263 PMID:17229725 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
JBrowse link
G Txnrd2 thioredoxin reductase 2 decreases activity EXP Gold Sodium Thiomalate results in decreased activity of TXNRD2 protein CTD PMID:15458826 NCBI chr11:96,024,321...96,072,475
Ensembl chr11:96,024,324...96,072,475
JBrowse link
stavudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Stavudine results in increased expression of ABCB1 mRNA CTD PMID:18310046 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO Stavudine results in decreased expression of ADIPOQ protein
Stavudine results in decreased expression of ADIPOQ mRNA; Stavudine results in decreased expression of ADIPOQ protein
CTD PMID:15865214 PMID:17503663 PMID:17668557 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:91,226,180...91,240,169
JBrowse link
G Alb albumin affects binding ISO Stavudine binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon decreases expression EXP Stavudine results in decreased expression of ATP5F1E mRNA CTD PMID:18299183 NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:183,677,273...183,680,214
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Stavudine results in decreased expression of BCL2 protein CTD PMID:9007205 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression EXP Stavudine results in increased expression of BCL2L1 mRNA CTD PMID:18299183 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:161,745,540...161,764,907
Ensembl chr 1:161,745,540...161,764,907
JBrowse link
G Casp3 caspase 3 increases cleavage ISO Stavudine results in increased cleavage of CASP3 protein CTD PMID:32278789 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Stavudine results in increased expression of CCL2 protein CTD PMID:17668557 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A affects expression ISO Stavudine affects the expression of CDKN1A protein CTD PMID:18389896 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A affects expression ISO Stavudine affects the expression of CDKN2A protein CTD PMID:18389896 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO Stavudine results in decreased expression of CEBPA protein CTD PMID:15722030 NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:96,896,171...96,899,309
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Stavudine results in increased expression of CEBPB mRNA CTD PMID:18299183 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Stavudine results in increased phosphorylation of CHEK1 protein CTD PMID:32278789 NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:44,609,417...44,629,359
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO Stavudine results in increased expression of CPT1A mRNA CTD PMID:14576092 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:209,993,875...210,056,326
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP Stavudine results in increased expression of CYP3A11 mRNA CTD PMID:18299183 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Fasn fatty acid synthase multiple interactions
decreases expression
ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of FASN mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of FASN mRNA
Stavudine results in decreased expression of FASN protein
CTD PMID:11741158 PMID:15722030 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,570,413...106,588,583
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression EXP Stavudine results in increased expression of FTH1 mRNA CTD PMID:18299183 NCBI chr 1:216,052,037...216,054,325
Ensembl chr 1:216,051,998...216,055,214
JBrowse link
G Gan gigaxonin decreases expression ISO Stavudine results in decreased expression of GAN mRNA; Stavudine results in decreased expression of GAN protein CTD PMID:19398414 NCBI chr19:62,116,600...62,173,879
Ensembl chr19:62,116,600...62,163,083
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression EXP Stavudine results in increased expression of GCLC mRNA CTD PMID:18299183 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:87,510,463...87,548,893
JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression EXP Stavudine results in decreased expression of GPX4 mRNA CTD PMID:18299183 NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:10,300,832...10,303,629
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP Stavudine results in increased expression of GSTA1 mRNA CTD PMID:18299183 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:31,199,888...31,211,528
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression EXP Stavudine results in increased expression of GSTP1 mRNA CTD PMID:18299183 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:210,767,237...210,769,705
JBrowse link
G Hfe homeostatic iron regulator multiple interactions ISO HFE gene SNP affects the susceptibility to [Didanosine co-treated with Stavudine] CTD PMID:16847405 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,841,252...41,851,208
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression ISO Stavudine affects the expression of HSPD1 protein CTD PMID:27041070 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:64,073,611...64,084,037
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression EXP Stavudine results in increased expression of IGFBP1 mRNA CTD PMID:18299183 NCBI chr14:86,261,277...86,266,344
Ensembl chr14:86,261,277...86,266,344
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Stavudine results in increased expression of IL1B protein CTD PMID:17668557 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:137,030,205...137,036,601
JBrowse link
G Il6 interleukin 6 increases expression ISO Stavudine results in increased expression of IL6 protein CTD PMID:17668557 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Stavudine results in increased expression of JUN mRNA CTD PMID:18299183 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:114,973,151...115,013,285
JBrowse link
G Lep leptin decreases expression ISO Stavudine results in decreased expression of LEP protein CTD PMID:17668557 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:58,626,523...58,640,661
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial affects expression ISO Stavudine affects the expression of LONP1 protein CTD PMID:27041070 NCBI chr 9:1,534,581...1,546,908
Ensembl chr 9:1,534,584...1,547,427
JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] affects the expression of LPL mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of LPL mRNA; [Stavudine co-treated with Lamivudine] affects the expression of LPL mRNA CTD PMID:11741158 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 decreases phosphorylation ISO Stavudine results in decreased phosphorylation of MAPK8 protein CTD PMID:27041070 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Me1 malic enzyme 1 multiple interactions
increases expression
ISO [Stavudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine co-treated with Nelfinavir] results in decreased expression of ME1 mRNA; [Stavudine co-treated with Lamivudine] results in increased expression of ME1 mRNA
Stavudine results in increased expression of ME1 mRNA
CTD PMID:11741158 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:96,429,057...96,540,275
JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions
decreases expression
EXP Carnitine inhibits the reaction [Stavudine results in decreased expression of MTTP mRNA] CTD PMID:18299183 NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:229,286,501...229,327,650
JBrowse link
G Nrf1 nuclear respiratory factor 1 increases expression ISO Stavudine results in increased expression of NRF1 mRNA CTD PMID:17926646 NCBI chr 4:59,632,366...59,738,166
Ensembl chr 4:59,632,372...59,738,353
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression
decreases expression
EXP
ISO
Stavudine results in increased expression of PCNA mRNA
Stavudine results in decreased expression of PCNA protein
CTD PMID:18299183 PMID:32278789 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Stavudine results in decreased expression of PPARG mRNA
Stavudine results in decreased expression of PPARG mRNA; Stavudine results in decreased expression of PPARG protein
CTD PMID:14518702 PMID:15722030 PMID:17926646 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Stavudine results in decreased expression of PTGS2 protein CTD PMID:18389896 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Sirt3 sirtuin 3 increases expression ISO Stavudine results in increased expression of SIRT3 protein CTD PMID:27041070 NCBI chr 1:205,371,703...205,394,145
Ensembl chr 1:205,371,710...205,394,076
JBrowse link
G Slc25a19 solute carrier family 25 member 19 multiple interactions ISO SLC25A19 protein affects the susceptibility to [Stavudine co-treated with Lamivudine co-treated with Indinavir] CTD PMID:15951836 NCBI chr10:101,353,426...101,366,551
Ensembl chr10:101,350,106...101,366,351
JBrowse link
G Slc25a5 solute carrier family 25 member 5 increases expression EXP Stavudine results in increased expression of SLC25A5 mRNA CTD PMID:18299183 NCBI chr  X:120,897,616...120,900,683
Ensembl chr  X:120,897,563...120,900,688
JBrowse link
G Slc29a3 solute carrier family 29 member 3 affects transport ISO SLC29A3 protein affects the transport of Stavudine CTD PMID:19164483 NCBI chr20:29,191,086...29,228,299
Ensembl chr20:29,191,127...29,228,299
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression
EXP Carnitine inhibits the reaction [Stavudine results in increased expression of SREBF1 mRNA] CTD PMID:18299183 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases expression EXP Stavudine results in decreased expression of STAT3 mRNA CTD PMID:18299183 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Stavudine results in decreased expression of TFAP2A mRNA CTD PMID:17926646 NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,229,910...24,253,219
JBrowse link
G Tnf tumor necrosis factor increases expression ISO Stavudine results in increased expression of TNF protein CTD PMID:17668557 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tymp thymidine phosphorylase increases expression ISO Stavudine results in increased expression of TYMP protein CTD PMID:16457948 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:122,316,520...122,324,003
JBrowse link
G Ucp1 uncoupling protein 1 decreases expression
increases expression
ISO Stavudine results in decreased expression of UCP1 mRNA
Stavudine results in increased expression of UCP1
CTD PMID:16038477 PMID:17926646 NCBI chr19:41,713,350...41,721,421
Ensembl chr19:41,713,351...41,721,420
JBrowse link
G Ucp2 uncoupling protein 2 decreases expression ISO Stavudine results in decreased expression of UCP2 mRNA CTD PMID:14518702 NCBI chr 1:164,251,373...164,257,742
Ensembl chr 1:164,251,373...164,257,743
JBrowse link
G Ucp3 uncoupling protein 3 decreases expression ISO Stavudine results in decreased expression of UCP3 mRNA CTD PMID:14518702 NCBI chr 1:164,227,910...164,240,893
Ensembl chr 1:164,227,882...164,241,210
JBrowse link
telbivudine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calcb calcitonin-related polypeptide, beta increases expression EXP Telbivudine results in increased expression of CALCB mRNA CTD PMID:37852574 NCBI chr 1:178,399,634...178,404,654
Ensembl chr 1:178,399,785...178,404,654
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Telbivudine results in increased expression of CEBPB mRNA CTD PMID:37852574 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:176,816,859...176,838,072
JBrowse link
G Clec2g C-type lectin domain family 2, member G increases expression EXP Telbivudine results in increased expression of CLEC2G mRNA CTD PMID:37852574 NCBI chr 4:164,303,865...164,313,737
Ensembl chr 4:164,300,076...164,314,591
JBrowse link
G Ddx3y DEAD box helicase 3, Y-linked increases expression EXP Telbivudine results in increased expression of DDX3Y mRNA CTD PMID:37852574 NCBI chr  Y:1,190,042...1,210,699
Ensembl chr  Y:1,191,242...1,210,650
JBrowse link
G Kdm5d lysine demethylase 5D increases expression EXP Telbivudine results in increased expression of KDM5D mRNA CTD PMID:37852574 NCBI chr  Y:551,621...647,742
Ensembl chr  Y:564,261...660,970
JBrowse link
G Mc2r melanocortin 2 receptor decreases expression EXP Telbivudine results in decreased expression of MC2R mRNA CTD PMID:37852574 NCBI chr18:64,279,878...64,291,775
Ensembl chr18:64,277,360...64,291,881
JBrowse link
G Mt-co2 mitochondrially encoded cytochrome c oxidase II decreases expression ISO Telbivudine results in decreased expression of COX2 protein CTD PMID:37659625 NCBI chr MT:7,006...7,689
Ensembl chr MT:6,991...7,674
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 decreases expression EXP Telbivudine results in decreased expression of MTARC1 mRNA CTD PMID:37852574 NCBI chr13:98,854,235...98,894,208
Ensembl chr13:98,871,289...98,894,252
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 decreases expression ISO Telbivudine results in decreased expression of NDUFB8 protein CTD PMID:37659625 NCBI chr 1:253,357,878...253,362,936
Ensembl chr 1:253,357,841...253,362,936
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 decreases expression EXP Telbivudine results in decreased expression of PCK1 mRNA CTD PMID:37852574 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20874
    role 20844
      biological role 20831
        biochemical role 19888
          enzyme inhibitor 18710
            EC 2.* (transferase) inhibitor 14864
              EC 2.7.* (P-containing group transferase) inhibitor 14367
                EC 2.7.7.* (nucleotidyltransferase) inhibitor 1179
                  DNA polymerase inhibitor 772
                    3,4,5-tri-O-galloylquinic acid 0
                    EC 2.7.7.48 (RNA-directed RNA polymerase) inhibitor + 79
                    EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor + 300
                    EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor + 480
paths to the root