|
G |
A2m |
alpha-2-macroglobulin |
decreases expression |
ISO |
potassium bromate results in decreased expression of A2M mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 4:154,309,426...154,359,138
|
|
G |
Agtr2 |
angiotensin II receptor, type 2 |
multiple interactions |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr X:119,389,480...119,393,845
Ensembl chr X:119,390,013...119,393,842
|
|
G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
multiple interactions affects expression |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AKR1B10 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
|
|
G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
increases expression |
EXP |
potassium bromate results in increased expression of AKR1C2 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
|
|
G |
Amigo2 |
adhesion molecule with Ig like domain 2 |
decreases expression |
ISO |
potassium bromate results in decreased expression of AMIGO2 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 7:138,704,124...138,707,221
Ensembl chr 7:138,704,126...138,707,221
|
|
G |
Anos1 |
anosmin 1 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of WFDC17 mRNA] |
CTD |
PMID:27082013 |
|
Ensembl chr10:70,999,780...71,000,627
|
|
G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
increases expression |
ISO |
potassium bromate results in increased expression of APEX1 mRNA |
CTD |
PMID:22539617 |
|
NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
|
|
G |
App |
amyloid beta precursor protein |
increases expression |
ISO |
potassium bromate results in increased expression of APP mRNA |
CTD |
PMID:30008028 |
|
NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
|
|
G |
Areg |
amphiregulin |
multiple interactions affects expression |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AREG mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
|
|
G |
Arg1 |
arginase 1 |
decreases expression |
ISO |
potassium bromate results in decreased expression of ARG1 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
|
|
G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
affects expression |
ISO |
potassium bromate affects the expression of ASNS mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
|
|
G |
Atf3 |
activating transcription factor 3 |
increases expression multiple interactions |
EXP ISO |
potassium bromate results in increased expression of ATF3 mRNA [potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA] |
CTD |
PMID:23588252 PMID:27082013 |
|
NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
|
|
G |
Atm |
ATM serine/threonine kinase |
decreases expression |
ISO |
potassium bromate results in decreased expression of ATM mRNA |
CTD |
PMID:22539617 |
|
NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
|
|
G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
decreases expression |
ISO |
potassium bromate results in decreased expression of ATP1B1 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
|
|
G |
Atp2b3 |
ATPase plasma membrane Ca2+ transporting 3 |
decreases expression |
EXP |
potassium bromate results in decreased expression of ATP2B3 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr X:157,236,400...157,312,028
Ensembl chr X:157,239,306...157,312,028
|
|
G |
Baat |
bile acid CoA:amino acid N-acyltransferase |
decreases expression |
ISO |
potassium bromate results in decreased expression of BAAT mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
|
|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
potassium bromate results in increased expression of BAX mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
|
|
G |
Bbox1 |
gamma-butyrobetaine hydroxylase 1 |
decreases expression |
ISO |
potassium bromate results in decreased expression of BBOX1 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
|
|
G |
Blnk |
B-cell linker |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of BLNK mRNA [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BLNK mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 1:260,187,023...260,254,490
Ensembl chr 1:260,186,967...260,254,600
|
|
G |
Bmf |
Bcl2 modifying factor |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of BMF mRNA [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BMF mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
|
|
G |
Brca1 |
BRCA1, DNA repair associated |
increases expression |
ISO |
potassium bromate results in increased expression of BRCA1 mRNA |
CTD |
PMID:22539617 |
|
NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
|
|
G |
Ca3 |
carbonic anhydrase 3 |
decreases expression |
EXP |
potassium bromate results in decreased expression of CA3 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
|
|
G |
Ca6 |
carbonic anhydrase 6 |
multiple interactions |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CAR6 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 5:167,226,246...167,244,786
Ensembl chr 5:167,226,246...167,244,786
|
|
G |
Cars |
cysteinyl-tRNA synthetase |
decreases expression |
ISO |
potassium bromate results in decreased expression of CARS1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
|
|
G |
Cat |
catalase |
decreases activity multiple interactions increases activity |
ISO EXP |
potassium bromate results in decreased activity of CAT protein vanillin inhibits the reaction [potassium bromate results in increased activity of CAT protein] Taurine inhibits the reaction [potassium bromate results in decreased activity of CAT protein] |
CTD |
PMID:22012894 PMID:25213677 PMID:26296324 PMID:27074584 |
|
NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
|
|
G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression multiple interactions |
EXP ISO |
potassium bromate results in increased expression of CCL20 mRNA [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CCL20 mRNA] |
CTD |
PMID:23588252 PMID:27082013 |
|
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
|
|
G |
Ccnb1 |
cyclin B1 |
multiple interactions increases expression |
ISO |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CCNB1 protein] |
CTD |
PMID:20067818 |
|
NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
|
|
G |
Ccno |
cyclin O |
decreases expression |
ISO |
potassium bromate results in decreased expression of CCNO mRNA |
CTD |
PMID:22539617 |
|
NCBI chr 2:44,857,043...44,860,317
Ensembl chr 2:44,857,213...44,860,315
|
|
G |
Cdhr1 |
cadherin-related family member 1 |
increases expression |
EXP |
potassium bromate results in increased expression of CDHR1 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr16:14,328,161...14,348,049
Ensembl chr16:14,328,160...14,348,046
|
|
G |
Cdk1 |
cyclin-dependent kinase 1 |
increases phosphorylation |
ISO |
potassium bromate results in increased phosphorylation of CDK1 protein |
CTD |
PMID:20067818 |
|
NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
|
|
G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression affects methylation affects expression multiple interactions |
ISO EXP |
potassium bromate results in increased expression of CDKN1A mRNA; potassium bromate results in increased expression of CDKN1A protein potassium bromate affects the methylation of CDKN1A gene potassium bromate affects the expression of CDKN1A mRNA; potassium bromate affects the expression of CDKN1A protein 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; Azacitidine inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; trichostatin A inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein] |
CTD |
PMID:20067818 PMID:23588252 PMID:23811332 PMID:25015661 PMID:30008028 PMID:30559759 |
|
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
|
|
G |
Cfd |
complement factor D |
decreases expression |
EXP |
potassium bromate results in decreased expression of CFD mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
|
|
G |
Chac1 |
ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
increases expression |
EXP |
potassium bromate results in increased expression of CHAC1 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
|
|
G |
Cldn2 |
claudin 2 |
decreases expression |
ISO |
potassium bromate results in decreased expression of CLDN2 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr X:111,122,552...111,133,188
Ensembl chr X:111,122,552...111,137,769
|
|
G |
Clu |
clusterin |
increases expression |
EXP |
potassium bromate results in increased expression of CLU protein |
CTD |
PMID:23159986 PMID:23588252 PMID:23811332 |
|
NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
|
|
G |
Coch |
cochlin |
decreases expression |
EXP |
potassium bromate results in decreased expression of COCH mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 6:72,359,702...72,373,710
Ensembl chr 6:72,359,791...72,373,695
|
|
G |
Comt |
catechol-O-methyltransferase |
increases expression |
EXP |
potassium bromate results in increased expression of COMT mRNA |
CTD |
PMID:23588252 |
|
NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
|
|
G |
Csrp3 |
cysteine and glycine rich protein 3 |
increases expression |
EXP |
potassium bromate results in increased expression of CSRP3 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
|
|
G |
Cth |
cystathionine gamma-lyase |
increases methylation |
ISO |
potassium bromate results in increased methylation of CTH promoter |
CTD |
PMID:30559759 |
|
NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
|
|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CXCL3 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
|
|
G |
Cyp2c7 |
cytochrome P450, family 2, subfamily c, polypeptide 7 |
decreases expression increases expression |
EXP |
potassium bromate results in decreased expression of CYP2C7 mRNA potassium bromate results in increased expression of CYP2C7 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 1:147,422,999...148,119,979
Ensembl chr 1:148,053,687...148,119,857
|
|
G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
multiple interactions affects expression |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of CYP2D22 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
|
|
G |
Cyp3a62 |
cytochrome P450, family 3, subfamily a, polypeptide 62 |
decreases expression |
ISO |
potassium bromate results in decreased expression of CYP3A4 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
|
|
G |
Ddb2 |
damage specific DNA binding protein 2 |
increases expression |
ISO |
potassium bromate results in increased expression of DDB2 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
|
|
G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
potassium bromate results in increased expression of DDIT3 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
|
|
G |
Dio3 |
iodothyronine deiodinase 3 |
multiple interactions |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
|
|
G |
Dsc1 |
desmocollin 1 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of DSC1 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr18:11,877,918...11,906,828
Ensembl chr18:11,877,561...11,906,827
|
|
G |
Dusp2 |
dual specificity phosphatase 2 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of DUSP2 mRNA [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of DUSP2 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
|
|
G |
Egr4 |
early growth response 4 |
multiple interactions affects expression |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of EGR4 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
|
|
G |
Ercc4 |
ERCC excision repair 4, endonuclease catalytic subunit |
decreases expression |
ISO |
potassium bromate results in decreased expression of ERCC4 mRNA |
CTD |
PMID:22539617 |
|
NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
|
|
G |
Ercc6 |
ERCC excision repair 6, chromatin remodeling factor |
affects response to substance multiple interactions |
ISO |
ERCC6 protein affects the susceptibility to potassium bromate veliparib promotes the reaction [ERCC6 protein affects the susceptibility to potassium bromate] |
CTD |
PMID:25136123 |
|
NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
|
|
G |
Ereg |
epiregulin |
increases expression |
ISO |
potassium bromate results in increased expression of EREG mRNA |
CTD |
PMID:30008028 |
|
NCBI chr14:18,577,620...18,591,395
Ensembl chr14:18,576,355...18,591,394
|
|
G |
Fas |
Fas cell surface death receptor |
increases expression |
ISO |
potassium bromate results in increased expression of FAS mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
|
|
G |
Fbxo22 |
F-box protein 22 |
increases expression |
ISO |
potassium bromate results in increased expression of FBXO22 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 8:59,770,032...59,786,061
Ensembl chr 8:59,769,994...59,786,065
|
|
G |
Fen1 |
flap structure-specific endonuclease 1 |
decreases expression |
ISO |
potassium bromate results in decreased expression of FEN1 mRNA |
CTD |
PMID:22539617 |
|
NCBI chr 1:226,251,516...226,256,160
Ensembl chr 1:226,251,518...226,255,886
|
|
G |
Fgb |
fibrinogen beta chain |
increases expression |
EXP |
potassium bromate results in increased expression of FGB mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
|
|
G |
Fgl2 |
fibrinogen-like 2 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of FGL2 mRNA [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of FGL2 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 4:10,323,598...10,329,241
Ensembl chr 4:10,323,607...10,329,241
|
|
G |
Fry |
FRY microtubule binding protein |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of FRY mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr12:5,573,729...5,822,874
Ensembl chr12:5,573,729...5,822,874
|
|
G |
Fth1 |
ferritin heavy chain 1 |
increases expression |
ISO |
potassium bromate results in increased expression of FTH1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
|
|
G |
Fzd2 |
frizzled class receptor 2 |
multiple interactions |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
|
|
G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions decreases activity |
EXP |
Taurine inhibits the reaction [potassium bromate results in decreased activity of G6PD protein] |
CTD |
PMID:25213677 |
|
NCBI chr X:156,274,800...156,293,935
Ensembl chr X:156,274,800...156,293,926
|
|
G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
potassium bromate results in increased expression of GADD45A mRNA |
CTD |
PMID:30008028 PMID:30559759 |
|
NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
|
|
G |
Gclm |
glutamate cysteine ligase, modifier subunit |
increases expression increases methylation |
ISO |
potassium bromate results in increased expression of GCLM mRNA potassium bromate results in increased methylation of GCLM promoter |
CTD |
PMID:30008028 PMID:30559759 |
|
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
|
|
G |
Gcnt3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
increases expression |
ISO |
potassium bromate results in increased expression of GCNT3 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 8:76,449,078...76,459,431
Ensembl chr 8:76,449,081...76,452,554
|
|
G |
Gpr87 |
G protein-coupled receptor 87 |
increases expression |
ISO |
potassium bromate results in increased expression of GPR87 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 2:149,398,949...149,418,041
Ensembl chr 2:149,398,949...149,417,212
|
|
G |
Grifin |
galectin-related inter-fiber protein |
decreases expression |
EXP |
potassium bromate results in decreased expression of GRIFIN mRNA |
CTD |
PMID:23588252 |
|
NCBI chr12:16,170,108...16,172,144
Ensembl chr12:16,170,162...16,172,129
|
|
G |
Gsr |
glutathione-disulfide reductase |
decreases activity multiple interactions |
ISO EXP |
potassium bromate results in decreased activity of GSR protein Taurine inhibits the reaction [potassium bromate results in decreased activity of GSR protein] |
CTD |
PMID:22012894 PMID:25213677 |
|
NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
|
|
G |
Gsta5 |
glutathione S-transferase alpha 5 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of GSTA5 mRNA [potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of GSTA5 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
|
|
G |
H2ax |
H2A.X variant histone |
multiple interactions increases phosphorylation |
ISO EXP |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein; bisphenol A inhibits the reaction [[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein] potassium bromate results in increased phosphorylation of H2AX protein Azacitidine inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein]; trichostatin A inhibits the reaction [potassium bromate results in increased phosphorylation of H2AX protein] |
CTD |
PMID:25015661 PMID:25693136 |
|
NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
|
|
G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
EXP |
potassium bromate results in increased expression of HAVCR1 mRNA; potassium bromate results in increased expression of HAVCR1 protein |
CTD |
PMID:23588252 PMID:23811332 |
|
NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
ceric oxide inhibits the reaction [potassium bromate results in increased expression of HMOX1 mRNA] |
CTD |
PMID:25618551 PMID:30008028 PMID:30559759 |
|
NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
|
|
G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
increases expression decreases expression |
ISO |
potassium bromate results in increased expression of HNF4A mRNA potassium bromate results in decreased expression of HNF4A mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
|
|
G |
Hp |
haptoglobin |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of HP mRNA [potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of HP mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
|
|
G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HPGD mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
|
|
G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
increases mutagenesis |
ISO |
potassium bromate results in increased mutagenesis of HPRT gene potassium bromate results in increased mutagenesis of HPRT1 gene |
CTD |
PMID:19853637 PMID:22539617 |
|
NCBI chr X:158,196,640...158,228,815
Ensembl chr X:158,197,149...158,228,749
|
|
G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
increases expression |
EXP |
potassium bromate results in increased expression of IGFBP1 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
|
|
G |
Ikzf2 |
IKAROS family zinc finger 2 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of IKZF2 mRNA [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IKZF2 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 9:76,621,230...76,771,017
Ensembl chr 9:76,621,230...76,768,806
|
|
G |
Il18r1 |
interleukin 18 receptor 1 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of IL18R1 mRNA [potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IL18R1 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 9:47,184,404...47,217,403
Ensembl chr 9:47,185,443...47,219,175
|
|
G |
Il1b |
interleukin 1 beta |
increases expression multiple interactions |
EXP ISO |
potassium bromate results in increased expression of IL1B mRNA vanillin inhibits the reaction [potassium bromate results in increased expression of IL1B mRNA] |
CTD |
PMID:23588252 PMID:26296324 |
|
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
|
|
G |
Il24 |
interleukin 24 |
increases expression |
EXP |
potassium bromate results in increased expression of IL24 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
|
|
G |
Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO |
potassium bromate results in increased expression of IL6 mRNA vanillin inhibits the reaction [potassium bromate results in increased expression of IL6 mRNA] |
CTD |
PMID:26296324 |
|
NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
|
|
G |
Kat2b |
lysine acetyltransferase 2B |
multiple interactions |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 9:4,440,982...4,492,949
|
|
G |
Kirrel3 |
kirre like nephrin family adhesion molecule 3 |
decreases expression |
EXP |
potassium bromate results in decreased expression of KIRREL3 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 8:35,692,525...36,254,755
Ensembl chr 8:36,125,999...36,254,753
|
|
G |
Klf15 |
Kruppel-like factor 15 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of KLF15 mRNA [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of KLF15 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 4:122,364,688...122,377,690
Ensembl chr 4:122,365,093...122,377,659
|
|
G |
Lcn2 |
lipocalin 2 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LCN2 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
|
|
G |
Lgals12 |
galectin 12 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LGALS12 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 1:222,891,626...222,903,728
Ensembl chr 1:222,891,626...222,902,320
|
|
G |
Lig3 |
DNA ligase 3 |
decreases expression |
ISO |
potassium bromate results in decreased expression of LIG3 mRNA |
CTD |
PMID:22539617 |
|
NCBI chr10:70,134,734...70,158,051
Ensembl chr10:70,134,729...70,158,055
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
potassium bromate results in increased phosphorylation of and results in increased activity of MAPK1 protein |
CTD |
PMID:20067818 |
|
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
potassium bromate results in increased phosphorylation of and results in increased activity of MAPK3 protein |
CTD |
PMID:20067818 |
|
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
increases expression |
ISO |
potassium bromate results in increased expression of MDM2 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
|
|
G |
Me1 |
malic enzyme 1 |
increases expression |
ISO |
potassium bromate results in increased expression of ME1 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
|
|
G |
Med1 |
mediator complex subunit 1 |
decreases phosphorylation |
ISO |
potassium bromate results in decreased phosphorylation of MED1 protein |
CTD |
PMID:25068892 |
|
NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880
|
|
G |
Mir126b |
microRNA 126b |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR126 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 3:4,042,488...4,042,560
|
|
G |
Mir134 |
microRNA 134 |
increases expression |
ISO |
potassium bromate results in increased expression of MIR134 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 6:133,884,547...133,884,619
Ensembl chr 6:133,884,531...133,884,633
|
|
G |
Mir137 |
microRNA 137 |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR137 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 2:221,658,106...221,658,207
Ensembl chr 2:221,658,106...221,658,207
|
|
G |
Mir146b |
microRNA 146b |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR146B mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
|
|
G |
Mir193a |
microRNA 193a |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR193A mRNA |
CTD |
PMID:30559759 |
|
NCBI chr10:67,065,885...67,065,996
Ensembl chr10:67,065,885...67,065,996
|
|
G |
Mir193b |
microRNA 193b |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR193B mRNA |
CTD |
PMID:30559759 |
|
NCBI chr14:30,331,049...30,331,131
Ensembl chr14:30,331,049...30,331,131
|
|
G |
Mir205 |
microRNA 205 |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR205 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr13:112,233,283...112,233,390
Ensembl chr13:112,233,283...112,233,390
|
|
G |
Mir21 |
microRNA 21 |
increases expression |
ISO |
potassium bromate results in increased expression of MIR21 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
|
|
G |
Mir23b |
microRNA 23b |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR23B mRNA |
CTD |
PMID:30559759 |
|
NCBI chr17:823,222...823,318
Ensembl chr17:823,222...823,318
|
|
G |
Mir29b1 |
microRNA 29b-1 |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR29B1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 4:58,344,310...58,344,390
Ensembl chr 4:58,344,310...58,344,390
|
|
G |
Mir322 |
microRNA 322 |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR424 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr X:158,148,161...158,148,255
Ensembl chr X:158,148,161...158,148,255
|
|
G |
Mir331 |
microRNA 331 |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR331 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
|
|
G |
Mir542 |
microRNA 542 |
decreases expression |
ISO |
potassium bromate results in decreased expression of MIR542 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr X:158,152,146...158,152,224
Ensembl chr X:158,152,146...158,152,224
|
|
G |
Mmp15 |
matrix metallopeptidase 15 |
multiple interactions |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr19:10,079,881...10,101,380
Ensembl chr19:10,079,765...10,101,451
|
|
G |
Mt1 |
metallothionein 1 |
increases expression multiple interactions |
ISO |
potassium bromate results in increased expression of MT1 mRNA vanillin inhibits the reaction [potassium bromate results in increased expression of MT1 mRNA] |
CTD |
PMID:27074584 |
|
NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
|
|
G |
Mt2A |
metallothionein 2A |
multiple interactions increases expression |
ISO |
vanillin inhibits the reaction [potassium bromate results in increased expression of MT2 mRNA] |
CTD |
PMID:27074584 |
|
NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
|
|
G |
Mthfd2 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
increases expression |
EXP |
potassium bromate results in increased expression of MTHFD2 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
|
|
G |
Muc1 |
mucin 1, cell surface associated |
decreases expression |
ISO |
potassium bromate results in decreased expression of MUC1 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
|
|
G |
Mutyh |
mutY DNA glycosylase |
decreases expression |
ISO |
potassium bromate results in decreased expression of MUTYH mRNA |
CTD |
PMID:22539617 |
|
NCBI chr 5:135,663,328...135,675,348
Ensembl chr 5:135,663,371...135,675,344
|
|
G |
Myh1 |
myosin heavy chain 1 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH1 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr10:53,740,841...53,764,610
Ensembl chr10:53,713,938...53,848,347
|
|
G |
Myh2 |
myosin heavy chain 2 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH2 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr10:53,711,895...53,738,164
Ensembl chr10:53,713,938...53,848,347
|
|
G |
Mylk3 |
myosin light chain kinase 3 |
decreases expression |
EXP |
potassium bromate results in decreased expression of MYLK3 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr19:27,388,163...27,442,451
Ensembl chr19:27,404,712...27,441,536
|
|
G |
Nebl |
nebulette |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NEBL mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr17:84,141,014...84,247,038
Ensembl chr17:84,140,489...84,488,601
|
|
G |
Npr3 |
natriuretic peptide receptor 3 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NPR3 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
potassium bromate results in increased expression of NQO1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
|
|
G |
Ogg1 |
8-oxoguanine DNA glycosylase |
decreases response to substance |
ISO |
OGG1 gene mutant form results in decreased susceptibility to potassium bromate |
CTD |
PMID:25693136 |
|
NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
|
|
G |
Ostn |
osteocrin |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of OSTN mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr11:76,851,923...76,888,140
Ensembl chr11:76,851,322...76,888,178
|
|
G |
Phgdh |
phosphoglycerate dehydrogenase |
decreases expression |
ISO |
potassium bromate results in decreased expression of PHGDH mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
|
|
G |
Plch2 |
phospholipase C, eta 2 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of PLCH2 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 5:172,386,400...172,455,965
Ensembl chr 5:172,388,598...172,424,081
|
|
G |
Pnkp |
polynucleotide kinase 3'-phosphatase |
decreases expression |
ISO |
potassium bromate results in decreased expression of PNKP mRNA |
CTD |
PMID:22539617 |
|
NCBI chr 1:100,853,475...100,859,202
Ensembl chr 1:100,853,902...100,859,084
|
|
G |
Ppm1d |
protein phosphatase, Mg2+/Mn2+ dependent, 1D |
increases expression |
ISO |
potassium bromate results in increased expression of PPM1D mRNA |
CTD |
PMID:30559759 |
|
NCBI chr10:72,909,550...72,945,884
Ensembl chr10:72,909,550...72,945,884
|
|
G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
decreases methylation |
ISO |
potassium bromate results in decreased methylation of PPP1R15A promoter |
CTD |
PMID:30559759 |
|
NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
|
|
G |
Prg4 |
proteoglycan 4 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of PRG4 mRNA [potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PRG4 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr13:67,672,588...67,688,902
Ensembl chr13:67,672,878...67,688,477
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression multiple interactions |
ISO |
potassium bromate results in increased expression of PTGS2 mRNA [potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA]; vanillin inhibits the reaction [potassium bromate results in increased expression of PTGS2 mRNA] |
CTD |
PMID:26296324 PMID:27082013 |
|
NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
|
|
G |
Ptpn22 |
protein tyrosine phosphatase, non-receptor type 22 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of PTPN22 mRNA [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PTPN22 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 2:206,342,066...206,390,348
Ensembl chr 2:206,342,066...206,390,348
|
|
G |
Rab3gap2 |
RAB3 GTPase activating non-catalytic protein subunit 2 |
increases expression |
EXP |
potassium bromate results in increased expression of RAB3GAP2 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr13:103,157,806...103,229,010
Ensembl chr13:103,157,806...103,228,423
|
|
G |
Ren |
renin |
increases expression |
EXP |
potassium bromate results in increased expression of REN1 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
|
|
G |
Retn |
resistin |
decreases expression |
EXP |
potassium bromate results in decreased expression of RETN mRNA |
CTD |
PMID:23588252 |
|
NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
|
|
G |
Robo3 |
roundabout guidance receptor 3 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of ROBO3 mRNA [potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of ROBO3 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 8:39,892,792...39,923,735
Ensembl chr 8:39,892,792...39,907,478
|
|
G |
Rps27l |
ribosomal protein S27-like |
increases expression |
ISO |
potassium bromate results in increased expression of RPS27L mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
|
|
G |
Rrm2b |
ribonucleotide reductase regulatory TP53 inducible subunit M2B |
increases expression |
ISO |
potassium bromate results in increased expression of RRM2B mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 7:76,750,045...76,780,817
Ensembl chr 7:76,750,050...76,780,817
|
|
G |
S100a8 |
S100 calcium binding protein A8 |
increases expression |
EXP |
potassium bromate results in increased expression of S100A8 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
|
|
G |
S100a9 |
S100 calcium binding protein A9 |
decreases expression |
EXP |
potassium bromate results in decreased expression of S100A9 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
|
|
G |
Scd |
stearoyl-CoA desaturase |
decreases expression |
EXP |
potassium bromate results in decreased expression of SCD1 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
|
|
G |
Sertad1 |
SERTA domain containing 1 |
increases expression |
ISO |
potassium bromate results in increased expression of SERTAD1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 1:84,293,102...84,296,370
Ensembl chr 1:84,293,102...84,296,367
|
|
G |
Sesn1 |
sestrin 1 |
increases expression |
ISO |
potassium bromate results in increased expression of SESN1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
|
|
G |
Sfn |
stratifin |
increases expression |
ISO |
potassium bromate results in increased expression of SFN mRNA |
CTD |
PMID:30008028 PMID:30559759 |
|
NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
|
|
G |
Slc26a4 |
solute carrier family 26 member 4 |
decreases expression |
EXP |
potassium bromate results in decreased expression of SLC26A4 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 6:50,809,103...50,848,443
Ensembl chr 6:50,808,923...50,846,965
|
|
G |
Slc26a7 |
solute carrier family 26 member 7 |
multiple interactions |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SLC26A7 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 5:27,986,656...28,131,294
Ensembl chr 5:27,986,663...28,177,340
|
|
G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
potassium bromate results in increased expression of SLC7A11 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
|
|
G |
Slc7a5 |
solute carrier family 7 member 5 |
increases expression |
ISO |
potassium bromate results in increased expression of SLC7A5 mRNA |
CTD |
PMID:30008028 |
|
NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
|
|
G |
Slco2b1 |
solute carrier organic anion transporter family, member 2b1 |
affects expression multiple interactions |
ISO |
potassium bromate affects the expression of SLCO2B1 mRNA [potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of SLCO2B1 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
|
|
G |
Sod1 |
superoxide dismutase 1 |
increases activity |
ISO |
potassium bromate results in increased activity of SOD1 protein |
CTD |
PMID:22012894 |
|
NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
|
|
G |
Sod2 |
superoxide dismutase 2 |
multiple interactions increases expression |
ISO |
ceric oxide inhibits the reaction [potassium bromate results in increased expression of SOD2 mRNA] |
CTD |
PMID:25618551 |
|
NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
|
|
G |
Spata22 |
spermatogenesis associated 22 |
decreases expression |
EXP |
potassium bromate results in decreased expression of SPATA22 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr10:59,893,064...59,910,769
Ensembl chr10:59,879,850...59,911,051
|
|
G |
Spp1 |
secreted phosphoprotein 1 |
increases expression |
EXP ISO |
potassium bromate results in increased expression of SPP1 mRNA; potassium bromate results in increased expression of SPP1 protein |
CTD |
PMID:23588252 PMID:23811332 PMID:30008028 |
|
NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
|
|
G |
Sqstm1 |
sequestosome 1 |
increases expression |
ISO |
potassium bromate results in increased expression of SQSTM1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
|
|
G |
Srxn1 |
sulfiredoxin 1 |
increases expression |
ISO |
potassium bromate results in increased expression of SRXN1 mRNA |
CTD |
PMID:22003191 PMID:30008028 |
|
NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
|
|
G |
Sult2a1 |
sulfotransferase family 2A member 1 |
increases expression |
EXP |
potassium bromate results in increased expression of SULT2A1 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr 1:76,558,721...76,614,315
Ensembl chr 1:76,252,329...76,780,230
|
|
G |
Tigar |
TP53 induced glycolysis regulatory phosphatase |
increases expression |
ISO |
potassium bromate results in increased expression of TIGAR mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
|
|
G |
Tk1 |
thymidine kinase 1 |
increases mutagenesis |
ISO |
potassium bromate results in increased mutagenesis of TK1 gene |
CTD |
PMID:19853637 |
|
NCBI chr10:106,817,556...106,828,888
Ensembl chr10:106,817,601...106,828,884
|
|
G |
Tmem163 |
transmembrane protein 163 |
decreases expression |
EXP |
potassium bromate results in decreased expression of TMEM163 mRNA |
CTD |
PMID:23588252 |
|
NCBI chr13:44,166,306...44,345,735
Ensembl chr13:44,166,306...44,345,735
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO |
vanillin inhibits the reaction [potassium bromate results in increased expression of TNF mRNA] |
CTD |
PMID:26296324 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
|
|
G |
Tnfsf9 |
TNF superfamily member 9 |
increases expression |
ISO |
potassium bromate results in increased expression of TNFSF9 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 9:9,909,942...9,912,276
Ensembl chr 9:9,909,948...9,912,276
|
|
G |
Tns1 |
tensin 1 |
multiple interactions |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 9:81,190,192...81,401,020
Ensembl chr 9:81,194,119...81,400,987
|
|
G |
Top3b |
DNA topoisomerase III beta |
decreases expression |
ISO |
potassium bromate results in decreased expression of TOP3B mRNA |
CTD |
PMID:22539617 |
|
NCBI chr11:88,346,305...88,374,896
Ensembl chr11:88,346,313...88,374,679
|
|
G |
Tp53 |
tumor protein p53 |
multiple interactions increases phosphorylation |
ISO EXP |
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein]; Ascorbic Acid inhibits the reaction [potassium bromate results in increased phosphorylation of TP53 protein] |
CTD |
PMID:20067818 PMID:25015661 |
|
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
|
|
G |
Tp53inp1 |
tumor protein p53 inducible nuclear protein 1 |
increases methylation increases expression |
ISO |
potassium bromate results in increased methylation of TP53INP1 promoter potassium bromate results in increased expression of TP53INP1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
|
|
G |
Triap1 |
TP53 regulated inhibitor of apoptosis 1 |
increases expression |
ISO |
potassium bromate results in increased expression of TRIAP1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr12:46,987,404...46,989,906
Ensembl chr12:46,987,404...46,989,897 Ensembl chr12:46,987,404...46,989,897
|
|
G |
Trib3 |
tribbles pseudokinase 3 |
increases expression |
EXP ISO |
potassium bromate results in increased expression of TRIB3 mRNA |
CTD |
PMID:23588252 PMID:30008028 |
|
NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
|
|
G |
Ubd |
ubiquitin D |
increases expression |
EXP |
potassium bromate results in increased expression of UBD mRNA |
CTD |
PMID:23588252 |
|
NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
|
|
G |
Vit |
vitrin |
multiple interactions |
ISO |
[potassium bromate co-treated with bisphenol A] affects the expression of VIT mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of VIT mRNA] |
CTD |
PMID:27082013 |
|
NCBI chr 6:1,091,817...1,208,888
Ensembl chr 6:1,147,012...1,208,392
|
|
G |
Wars1 |
tryptophanyl-tRNA synthetase 1 |
decreases expression |
ISO |
potassium bromate results in decreased expression of WARS1 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
|
|
G |
Xdh |
xanthine dehydrogenase |
increases activity multiple interactions |
EXP |
potassium bromate results in increased activity of XDH protein Taurine inhibits the reaction [potassium bromate results in increased activity of XDH protein] |
CTD |
PMID:25213677 |
|
NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
|
|
G |
Xrcc3 |
X-ray repair cross complementing 3 |
decreases expression |
ISO |
potassium bromate results in decreased expression of XRCC3 mRNA |
CTD |
PMID:22539617 |
|
NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
|
|
G |
Xrcc6 |
X-ray repair cross complementing 6 |
multiple interactions increases response to substance |
ISO |
[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AGTR2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ATF3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of DIO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of FZD2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of KAT2B mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of MMP15 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of TNS1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CAR6 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CCL20 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of CXCL3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of DSC1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of FRY mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HCAR2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of HPGD mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LCN2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of LGALS12 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of MYH2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NEBL mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of NPR3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of OSTN mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of PLCH2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SAA3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of SLC26A7 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [bisphenol A affects the expression of WFDC17 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AKR1B10 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of AREG mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BLNK mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of BMF mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of CYP2D22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of DUSP2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of EGR4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of FGL2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of GSTA5 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of HP mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IKZF2 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of IL18R1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of KLF15 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PRG4 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of PTPN22 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of ROBO3 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of SLCO2B1 mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [potassium bromate affects the expression of VIT mRNA]; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein; bisphenol A inhibits the reaction [[XRCC6 gene mutant form results in increased susceptibility to potassium bromate] which results in increased expression of H2AX protein] |
CTD |
PMID:25693136 PMID:27082013 |
|
NCBI chr 7:123,259,881...123,280,613
Ensembl chr 7:123,259,761...123,280,612
|
|
G |
Zmat3 |
zinc finger, matrin type 3 |
increases expression |
ISO |
potassium bromate results in increased expression of ZMAT3 mRNA |
CTD |
PMID:30559759 |
|
NCBI chr 2:118,715,229...118,746,109
Ensembl chr 2:118,721,334...118,745,766
|
|