CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: methylthio-1,3,5-triazine
Accession: CHEBI:38174
browse the term
Synonyms: related_synonym: methylthio-1,3,5-triazines
G
Cdh1
cadherin 1
decreases expression
EXP
ametryne results in decreased expression of CDH1 mRNA
CTD
PMID:26310382
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
G
Cdh2
cadherin 2
increases expression
EXP
ametryne results in increased expression of CDH2 mRNA
CTD
PMID:26310382
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
multiple interactions increases metabolic processing
ISO
POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of ametryne]
CTD
PMID:8971136
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Gja1
gap junction protein, alpha 1
decreases expression
EXP
ametryne results in decreased expression of GJA1 mRNA
CTD
PMID:26310382
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Gstm1
glutathione S-transferase mu 1
increases expression
EXP
ametryne results in increased expression of GSTM1 mRNA
CTD
PMID:26310382
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Por
cytochrome p450 oxidoreductase
multiple interactions
ISO
POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of ametryne]
CTD
PMID:8971136
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
G
Sod2
superoxide dismutase 2
increases expression
EXP
ametryne results in increased expression of SOD2 mRNA
CTD
PMID:26310382
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
Prometryne binds to and results in increased activity of NR1I2 protein
CTD
PMID:21115097
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
increases metabolic processing multiple interactions
ISO
CYP1A2 protein results in increased metabolism of terbutryne POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of terbutryne]
CTD
PMID:8971136
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
terbutryne binds to and results in increased activity of NR1I2 protein
CTD
PMID:20024649
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
G
Por
cytochrome p450 oxidoreductase
multiple interactions
ISO
POR protein promotes the reaction [CYP1A2 protein results in increased metabolism of terbutryne]
CTD
PMID:8971136
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all
Path 1
CHEBI ontology
19911
chemical entity
19909
atom
19909
nonmetal atom
19832
sulfur atom
17746
sulfur molecular entity
17770
sulfide
10116
organic sulfide
10116
methyl sulfide
74
methylthio-1,3,5-triazine
8
2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthio)-1,3,5-triazine
0
2-(methylthio)-1,3,5-triazine +
0
2-(methylthio)-4-phenyl-6-propan-2-yl-1,3,5-triazine
0
6-(methylthio)-1,3,5-triazine-2,4-diamine
0
ametryn
7
prometryn
1
simetryn
0
terbutryn
3
Path 2
CHEBI ontology
19911
subatomic particle
19909
composite particle
19909
hadron
19880
baryon
19880
nucleon
19909
atomic nucleus
19880
atom
19909
main group element atom
19849
p-block element atom
19849
carbon group element atom
19766
carbon atom
19785
organic molecular entity
19785
organic molecule
19737
organic cyclic compound
19526
organic heterocyclic compound
18870
heteroarene
17171
azaarene
7501
triazines
5424
1,3,5-triazines
5378
methylthio-1,3,5-triazine
8
2-(dichloromethyl)-4-(4-methylphenyl)-6-(methylthio)-1,3,5-triazine
0
2-(methylthio)-1,3,5-triazine +
0
2-(methylthio)-4-phenyl-6-propan-2-yl-1,3,5-triazine
0
6-(methylthio)-1,3,5-triazine-2,4-diamine
0
ametryn
7
prometryn
1
simetryn
0
terbutryn
3