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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dialdehyde
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Accession:CHEBI:38124 term browser browse the term
Definition:Any aldehyde with two aldehyde groups.
Synonyms:related_synonym: bialdehyde;   bialdehydes;   dialdehydes



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fumaraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]; [[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde; [CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde CTD PMID:21842885 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases secretion ISO FGF1 protein results in decreased secretion of malealdehyde CTD PMID:16222742 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO malealdehyde results in increased expression of GCLC mRNA CTD PMID:35750087 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects expression ISO malealdehyde affects the expression of GSTP1 mRNA CTD PMID:35750087 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hdac2 histone deacetylase 2 affects expression ISO malealdehyde affects the expression of HDAC2 mRNA CTD PMID:35750087 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac8 histone deacetylase 8 increases expression ISO malealdehyde results in increased expression of HDAC8 mRNA CTD PMID:35750087 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923
JBrowse link
G Hdac9 histone deacetylase 9 affects expression ISO malealdehyde affects the expression of HDAC9 mRNA CTD PMID:35750087 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO malealdehyde results in decreased expression of TP53 mRNA CTD PMID:35750087 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Txn1 thioredoxin 1 decreases activity ISO malealdehyde results in decreased activity of TXN1 protein CTD PMID:27402187 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
glutaraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 increases expression ISO Glutaral results in increased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Casp8 caspase 8 decreases expression ISO Glutaral results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Glutaral results in increased expression of CCL4 mRNA CTD PMID:20713136 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Cd86 CD86 molecule increases expression ISO Glutaral results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Glutaral results in decreased activity of G6PD protein CTD PMID:19490936 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Glutaral results in decreased expression of GJA1 protein CTD PMID:19932693 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
ISO Glutaral results in decreased activity of GSR protein
Idarubicin promotes the reaction [Glutaral results in decreased activity of GSR protein]
CTD PMID:19490936 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO Glutaral results in increased expression of IL1R2 mRNA CTD PMID:20713136 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
JBrowse link
G Il6 interleukin 6 affects expression ISO Glutaral affects the expression of IL6 mRNA CTD PMID:20200221 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Glutaral results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Tnf tumor necrosis factor affects expression
increases expression
ISO Glutaral affects the expression of TNF mRNA
Glutaral results in increased expression of TNF mRNA
CTD PMID:20200221 PMID:28236482 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Glutaral results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
glyoxal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions
increases degradation
ISO Glyoxal inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]
Glyoxal results in increased degradation of ABCA1 protein
Glyoxal inhibits the reaction [ABCA1 protein binds to APOA1 protein]
CTD PMID:15983222 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases reduction ISO AKR1B1 protein results in increased reduction of Glyoxal CTD PMID:10510318 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases activity
increases expression
ISO Glyoxal results in increased activity of AKR1C2 promoter
Glyoxal results in increased expression of AKR1C2 mRNA
CTD PMID:21195160 PMID:25724174 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [Chloral Hydrate results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyoxal; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyoxal CTD PMID:21334317 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO Glyoxal inhibits the reaction [ABCA1 protein binds to APOA1 protein] CTD PMID:15983222 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Glyoxal results in increased expression of ATF3 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions
increases expression
EXP Glyoxal promotes the reaction [Capsaicin results in increased expression of CAMP protein]
Glyoxal results in increased expression of CAMP protein
CTD PMID:29496360 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
JBrowse link
G Cat catalase decreases response to substance EXP CAT protein results in decreased susceptibility to Glyoxal CTD PMID:21334317 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Glyoxal results in decreased expression of COL1A1 mRNA CTD PMID:28760545 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Ctss cathepsin S decreases activity ISO Glyoxal results in decreased activity of CTSS protein CTD PMID:16671891 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions ISO [CYP2C19 protein results in increased metabolism of and results in increased susceptibility to sudoxicam] which results in increased chemical synthesis of Glyoxal CTD PMID:33253783 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO [CYP2C8 protein results in increased metabolism of and results in increased susceptibility to sudoxicam] which results in increased chemical synthesis of Glyoxal CTD PMID:33253783
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO [CYP3A4 protein results in increased metabolism of and results in increased susceptibility to sudoxicam] which results in increased chemical synthesis of Glyoxal CTD PMID:33253783 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Defb2 defensin beta 2 multiple interactions
increases expression
EXP Glyoxal promotes the reaction [Capsaicin results in increased expression of DEFB2 protein]
Glyoxal results in increased expression of DEFB2 protein
CTD PMID:29496360 NCBI chr16:70,231,870...70,245,817
Ensembl chr16:70,231,945...70,245,784
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Glyoxal results in increased expression of DNAJB4 mRNA CTD PMID:23999411 PMID:27965148 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Glyoxal results in increased expression of GCLM mRNA CTD PMID:27965148 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Glyoxal results in increased expression of HMOX1 mRNA CTD PMID:23445166 PMID:25724174 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 increases expression ISO Glyoxal results in increased expression of HSPA6 mRNA CTD PMID:23999411 NCBI chr13:83,273,176...83,274,317 JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 increases expression ISO Glyoxal results in increased expression of HSPH1 mRNA CTD PMID:23999411 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Ifng interferon gamma multiple interactions EXP [Capsaicin results in increased susceptibility to Glyoxal] which results in increased expression of IFNG mRNA CTD PMID:29496360 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il18 interleukin 18 increases expression ISO Glyoxal results in increased expression of IL18 protein CTD PMID:23063874 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Glyoxal results in increased expression of IL1A mRNA CTD PMID:33715048 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Glyoxal results in increased expression of IL1B mRNA CTD PMID:33715048 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 affects expression ISO Glyoxal analog affects the expression of IL6 mRNA CTD PMID:20200221 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO Glyoxal promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Capsaicin results in increased susceptibility to Glyoxal] which results in increased expression of TNF mRNA CTD PMID:29496360 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Glyoxal results in increased expression of TXNRD1 mRNA CTD PMID:23445166 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
malonaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO iron(II)-ascorbic acid complex promotes the reaction [Malondialdehyde results in increased expression of ABCA1 protein] CTD PMID:17070507 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO [ABCB1A mutant form co-treated with triptolide] results in increased abundance of Malondialdehyde CTD PMID:26134275 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP Malondialdehyde results in increased expression of ACTA2 protein CTD PMID:7593635 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Agt angiotensinogen increases abundance
multiple interactions
affects binding
EXP
ISO
AGT protein results in increased abundance of Malondialdehyde
Atorvastatin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]; isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde]
Malondialdehyde binds to AGT protein modified form
FNDC5 protein inhibits the reaction [AGT protein modified form results in increased abundance of Malondialdehyde]
CTD PMID:15607907 PMID:19451411 PMID:26111765 PMID:30354818 PMID:30703374 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [AKT1 gene mutant form co-treated with MET gene mutant form] results in increased abundance of Malondialdehyde; Orlistat inhibits the reaction [[AKT1 gene mutant form co-treated with MET gene mutant form] results in increased abundance of Malondialdehyde] CTD PMID:32045588 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin multiple interactions ISO ALB protein affects the reaction [[Iron co-treated with Bicarbonates] results in increased abundance of Malondialdehyde]; ALB protein inhibits the reaction [[Iron co-treated with Phosphates] results in increased abundance of Malondialdehyde] CTD PMID:16027354 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases metabolic processing
increases oxidation
ISO ALDH1A1 protein results in increased metabolism of Malondialdehyde
ALDH1A1 protein results in increased oxidation of Malondialdehyde
CTD PMID:21256123 PMID:22339434 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases oxidation ISO ALDH2 protein results in increased oxidation of Malondialdehyde CTD PMID:22339434 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases metabolic processing ISO ALDH3A1 protein results in increased metabolism of Malondialdehyde CTD PMID:21256123 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 affects binding ISO Malondialdehyde binds to ALDH3B1 protein CTD PMID:20699116 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
JBrowse link
G Apc APC regulator of WNT signaling pathway affects abundance
multiple interactions
ISO APC protein affects the abundance of Malondialdehyde
bis(2-guanidinoethyl)disulfide inhibits the reaction [APC protein affects the abundance of Malondialdehyde]; FeCl tetrakis-2-(triethyleneglycolmonomethylether)pyridylporphyrin inhibits the reaction [APC protein affects the abundance of Malondialdehyde]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [APC protein affects the abundance of Malondialdehyde]
CTD PMID:15063141 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases abundance
ISO vitexin inhibits the reaction [APP protein modified form results in increased abundance of Malondialdehyde] CTD PMID:29545167 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Atp7b ATPase copper transporting beta increases abundance EXP ATP7B gene mutant form results in increased abundance of Malondialdehyde CTD PMID:17303181 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
JBrowse link
G Bgn biglycan multiple interactions ISO [[BGN mRNA alternative form binds to OTUB1 protein] which binds to and results in decreased ubiquitination of and results in increased stability of SLC7A11 protein] which results in decreased abundance of Malondialdehyde CTD PMID:35234341 NCBI chr  X:151,197,296...151,209,458
Ensembl chr  X:151,197,273...151,209,461
JBrowse link
G Cat catalase decreases abundance
multiple interactions
EXP CAT protein modified form results in decreased abundance of Malondialdehyde
[SOD1 protein modified form co-treated with CAT protein modified form] results in decreased abundance of Malondialdehyde
CTD PMID:21600015 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO iron(II)-ascorbic acid complex promotes the reaction [Malondialdehyde results in increased expression of CD36 protein] CTD PMID:17070507 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO Malondialdehyde results in decreased expression of COL1A1 mRNA CTD PMID:28760545 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
multiple interactions
EXP Malondialdehyde results in increased expression of COL1A2 mRNA
MAPK8 protein promotes the reaction [Malondialdehyde results in increased expression of COL1A2 mRNA]
CTD PMID:11295527 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Cp ceruloplasmin affects abundance ISO CP protein affects the abundance of Malondialdehyde CTD PMID:12572680 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Cybb cytochrome b-245 beta chain increases abundance ISO CYBB protein results in increased abundance of Malondialdehyde CTD PMID:19417757 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Ddah2 DDAH family member 2, ADMA-independent multiple interactions ISO DDAH2 promotes the reaction [tetramethylpyrazine inhibits the reaction [Iron-Dextran Complex results in increased abundance of Malondialdehyde]] CTD PMID:32135237 NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 decreases expression EXP Malondialdehyde results in decreased expression of EEF2 protein CTD PMID:16469450 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 multiple interactions ISO [lead nitrate co-treated with EIF2AK1 gene mutant form] results in increased abundance of Malondialdehyde CTD PMID:25411909 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573
JBrowse link
G Epo erythropoietin decreases abundance ISO EPO protein results in decreased abundance of Malondialdehyde CTD PMID:22013135 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
JBrowse link
G Fndc5 fibronectin type III domain containing 5 multiple interactions
decreases abundance
ISO
EXP
FNDC5 protein inhibits the reaction [AGT protein modified form results in increased abundance of Malondialdehyde]
FNDC5 protein results in decreased abundance of Malondialdehyde
NFE2L2 protein promotes the reaction [FNDC5 protein results in decreased abundance of Malondialdehyde]
CTD PMID:30703374 PMID:32165127 NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO FOXO3 protein inhibits the reaction [SRT1720 inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of Malondialdehyde]] CTD PMID:24633890 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects abundance ISO GCLM gene polymorphism affects the abundance of Malondialdehyde CTD PMID:25728017 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide decreases abundance EXP GHRL results in decreased abundance of Malondialdehyde CTD PMID:16868036 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Gjb1 gap junction protein, beta 1 decreases abundance ISO GJB1 protein results in decreased abundance of Malondialdehyde CTD PMID:27859493 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects abundance ISO GSTT1 gene polymorphism affects the abundance of Malondialdehyde CTD PMID:25728017 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) decreases activity ISO Malondialdehyde results in decreased activity of H6PD protein CTD PMID:20211231 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO [cobaltiprotoporphyrin results in increased expression of HMOX1 protein] inhibits the reaction [Ethanol results in increased abundance of Malondialdehyde]; zinc protoporphyrin inhibits the reaction [[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] inhibits the reaction [Ethanol results in increased abundance of Malondialdehyde]] CTD PMID:15602829 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Trichloroethylene co-treated with Malondialdehyde analog] results in increased expression of IFNG protein CTD PMID:18267128 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta increases abundance ISO IL1B gene mutant form results in increased abundance of Malondialdehyde CTD PMID:37540211 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases abundance ISO IL1RN protein results in decreased abundance of Malondialdehyde CTD PMID:18474811 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Trichloroethylene co-treated with Malondialdehyde analog] results in increased expression of IL2 protein CTD PMID:18267128 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Kl Klotho multiple interactions
increases abundance
ISO Amino Acids inhibits the reaction [KL gene mutant form results in increased abundance of Malondialdehyde]; H 1356 inhibits the reaction [Amino Acids inhibits the reaction [KL gene mutant form results in increased abundance of Malondialdehyde]] CTD PMID:25309793 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP MAPK8 protein promotes the reaction [Malondialdehyde results in increased expression of COL1A2 mRNA] CTD PMID:11295527 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO Malondialdehyde promotes the reaction [MAPT protein binds to MAPT protein] CTD PMID:17082178 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase multiple interactions ISO [AKT1 gene mutant form co-treated with MET gene mutant form] results in increased abundance of Malondialdehyde; Orlistat inhibits the reaction [[AKT1 gene mutant form co-treated with MET gene mutant form] results in increased abundance of Malondialdehyde] CTD PMID:32045588 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Mettl14 methyltransferase 14, N6-adenosine-methyltransferase subunit multiple interactions ISO METTL14 protein promotes the reaction [Doxorubicin results in increased abundance of Malondialdehyde] CTD PMID:34648132 NCBI chr 2:211,530,598...211,546,845
Ensembl chr 2:211,530,602...211,546,821
JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 multiple interactions ISO MICAL2 mRNA promotes the reaction [Carbon Tetrachloride results in increased abundance of Malondialdehyde] CTD PMID:32659284 NCBI chr 1:166,345,853...166,530,575
Ensembl chr 1:166,345,859...166,471,719
Ensembl chr 1:166,345,859...166,471,719
JBrowse link
G Mir141 microRNA 141 increases abundance ISO MIR141 mRNA results in increased abundance of Malondialdehyde CTD PMID:26548909 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
JBrowse link
G Mir3545 microRNA 3545 multiple interactions ISO MIR203 mRNA inhibits the reaction [Carbon Tetrachloride results in increased abundance of Malondialdehyde] CTD PMID:32659284 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656
JBrowse link
G Myb MYB proto-oncogene, transcription factor increases expression EXP Malondialdehyde results in increased expression of MYB protein CTD PMID:7593635 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO
EXP
NFE2L2 protein inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of Malondialdehyde]
NFE2L2 protein promotes the reaction [FNDC5 protein results in decreased abundance of Malondialdehyde]
CTD PMID:24633890 PMID:32165127 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos2 nitric oxide synthase 2 decreases expression ISO Malondialdehyde results in decreased expression of NOS2 protein CTD PMID:20940037 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Otub1 OTU deubiquitinase, ubiquitin aldehyde binding 1 multiple interactions ISO [[BGN mRNA alternative form binds to OTUB1 protein] which binds to and results in decreased ubiquitination of and results in increased stability of SLC7A11 protein] which results in decreased abundance of Malondialdehyde CTD PMID:35234341 NCBI chr 1:204,387,215...204,395,495
Ensembl chr 1:204,387,215...204,395,483
JBrowse link
G Pon1 paraoxonase 1 multiple interactions ISO PON1 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Malondialdehyde] CTD PMID:20079818 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Pon3 paraoxonase 3 multiple interactions ISO PON3 protein inhibits the reaction [Carbon Tetrachloride results in increased abundance of Malondialdehyde] CTD PMID:20079818 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
JBrowse link
G Prkd2 protein kinase D2 multiple interactions ISO [PRKD2 protein affects the susceptibility to [erastin co-treated with bafilomycin A1]] which affects the abundance of Malondialdehyde; [PRKD2 protein affects the susceptibility to erastin] which affects the abundance of Malondialdehyde CTD PMID:37951334 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376
JBrowse link
G Pten phosphatase and tensin homolog increases abundance ISO PTEN mutant form results in increased abundance of Malondialdehyde CTD PMID:26548909 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Selenom selenoprotein M multiple interactions ISO [SELENOM protein affects the susceptibility to Melatonin] which affects the abundance of Malondialdehyde CTD PMID:36504304 NCBI chr14:78,395,826...78,398,429
Ensembl chr14:78,395,826...78,398,429
JBrowse link
G Shc1 SHC adaptor protein 1 multiple interactions ISO SHC1 protein promotes the reaction [Carbon Tetrachloride results in increased abundance of Malondialdehyde] CTD PMID:32659284 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO SIRT1 protein inhibits the reaction [Tobacco Smoke Pollution results in increased abundance of Malondialdehyde] CTD PMID:24633890 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc7a11 solute carrier family 7 member 11 multiple interactions ISO [[BGN mRNA alternative form binds to OTUB1 protein] which binds to and results in decreased ubiquitination of and results in increased stability of SLC7A11 protein] which results in decreased abundance of Malondialdehyde CTD PMID:35234341 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases abundance
EXP [SOD1 protein modified form co-treated with CAT protein modified form] results in decreased abundance of Malondialdehyde
SOD1 protein modified form results in decreased abundance of Malondialdehyde
CTD PMID:21600015 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tbx2 T-box transcription factor 2 multiple interactions EXP TBX2 protein promotes the reaction [Sevoflurane results in increased abundance of Malondialdehyde] CTD PMID:37494465 NCBI chr10:70,679,670...70,688,868
Ensembl chr10:70,679,518...70,688,529
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases abundance
ISO delphinidin inhibits the reaction [TGFB1 results in increased abundance of Malondialdehyde] CTD PMID:30365941 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases abundance
ISO Acetylcysteine inhibits the reaction [TNF results in increased abundance of Malondialdehyde] CTD PMID:17026986 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 increases mutagenesis ISO Malondialdehyde results in increased mutagenesis of TP53 gene CTD PMID:30658077 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases abundance
multiple interactions
increases abundance
ISO XRCC1 protein results in decreased abundance of Malondialdehyde
Acetylcysteine inhibits the reaction [XRCC1 gene mutant form results in increased abundance of Malondialdehyde]; Acetylcysteine promotes the reaction [XRCC1 protein results in decreased abundance of Malondialdehyde]
CTD PMID:30998386 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
phthalaldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation-induced cytidine deaminase affects expression ISO o-Phthalaldehyde affects the expression of AICDA mRNA CTD PMID:22302311 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 affects expression ISO o-Phthalaldehyde affects the expression of AKR1C18 mRNA CTD PMID:22302311 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 affects expression ISO o-Phthalaldehyde affects the expression of CCL6 mRNA CTD PMID:22302311 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Ccna2 cyclin A2 affects expression ISO o-Phthalaldehyde affects the expression of CCNA2 mRNA CTD PMID:22302311 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 affects expression ISO o-Phthalaldehyde affects the expression of CCNB1 mRNA CTD PMID:22302311 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccne2 cyclin E2 affects expression ISO o-Phthalaldehyde affects the expression of CCNE2 mRNA CTD PMID:22302311 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 affects expression ISO o-Phthalaldehyde affects the expression of CCR4 mRNA CTD PMID:22302311 NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056
JBrowse link
G Cd207 CD207 molecule affects expression ISO o-Phthalaldehyde affects the expression of CD207 mRNA CTD PMID:22302311 NCBI chr 4:116,155,229...116,161,587
Ensembl chr 4:116,155,212...116,161,518
JBrowse link
G Cd5l Cd5 molecule-like affects expression ISO o-Phthalaldehyde affects the expression of CD5L mRNA CTD PMID:22302311 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753
JBrowse link
G Cd83 CD83 molecule affects expression ISO o-Phthalaldehyde affects the expression of CD83 mRNA CTD PMID:22302311 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
JBrowse link
G Cdc20 cell division cycle 20 affects expression ISO o-Phthalaldehyde affects the expression of CDC20 mRNA CTD PMID:22302311 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25c cell division cycle 25C affects expression ISO o-Phthalaldehyde affects the expression of CDC25C mRNA CTD PMID:22302311 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects expression ISO o-Phthalaldehyde affects the expression of CDK1 mRNA CTD PMID:22302311 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Clec7a C-type lectin domain containing 7A affects expression ISO o-Phthalaldehyde affects the expression of CLEC7A mRNA CTD PMID:22302311 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain affects expression ISO o-Phthalaldehyde affects the expression of COL8A1 mRNA CTD PMID:22302311 NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
JBrowse link
G Cphx1 cytoplasmic polyadenylated homeobox 1 affects expression ISO o-Phthalaldehyde affects the expression of CPHX1 mRNA CTD PMID:22302311 NCBI chr16:1,533,883...1,537,248
Ensembl chr16:1,528,440...1,537,082
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 affects expression ISO o-Phthalaldehyde affects the expression of CTLA4 mRNA CTD PMID:22302311 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression ISO o-Phthalaldehyde results in decreased expression of CYP1A1 mRNA CTD PMID:20112102 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO o-Phthalaldehyde results in decreased expression of CYP2E1 mRNA CTD PMID:20112102 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO o-Phthalaldehyde results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dio2 iodothyronine deiodinase 2 decreases activity ISO o-Phthalaldehyde results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
JBrowse link
G Dio3 iodothyronine deiodinase 3 decreases activity ISO o-Phthalaldehyde results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
JBrowse link
G E2f1 E2F transcription factor 1 affects expression ISO o-Phthalaldehyde affects the expression of E2F1 mRNA CTD PMID:22302311 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Fabp7 fatty acid binding protein 7 affects expression ISO o-Phthalaldehyde affects the expression of FABP7 mRNA CTD PMID:22302311 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
JBrowse link
G Fxyd4 FXYD domain-containing ion transport regulator 4 affects expression ISO o-Phthalaldehyde affects the expression of FXYD4 mRNA CTD PMID:22302311 NCBI chr 4:151,109,779...151,113,659
Ensembl chr 4:151,109,779...151,113,637
JBrowse link
G Gzmb granzyme B affects expression ISO o-Phthalaldehyde affects the expression of GZMB mRNA CTD PMID:22302311 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814
JBrowse link
G Ifng interferon gamma increases expression ISO o-Phthalaldehyde results in increased expression of IFNG mRNA CTD PMID:21785612 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il10 interleukin 10 increases expression ISO o-Phthalaldehyde results in increased expression of IL10 mRNA CTD PMID:21785612 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B affects expression ISO o-Phthalaldehyde affects the expression of IL12B mRNA CTD PMID:22302311 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il13 interleukin 13 increases expression ISO o-Phthalaldehyde results in increased expression of IL13 mRNA CTD PMID:21785612 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1b interleukin 1 beta increases expression ISO o-Phthalaldehyde results in increased expression of IL1B mRNA CTD PMID:21785612 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il21 interleukin 21 affects expression ISO o-Phthalaldehyde affects the expression of IL21 mRNA CTD PMID:22302311 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha affects expression ISO o-Phthalaldehyde affects the expression of IL2RA mRNA CTD PMID:22302311 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
JBrowse link
G Il4 interleukin 4 affects expression
increases expression
ISO o-Phthalaldehyde affects the expression of IL4 mRNA
o-Phthalaldehyde results in increased expression of IL4 mRNA; o-Phthalaldehyde results in increased expression of IL4 protein
CTD PMID:19110043 PMID:20176622 PMID:21785612 PMID:22302311 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 increases expression ISO o-Phthalaldehyde results in increased expression of IL5 mRNA CTD PMID:19110043 PMID:21785612 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Itgav integrin subunit alpha V affects expression ISO o-Phthalaldehyde affects the expression of ITGAV mRNA CTD PMID:22302311 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO o-Phthalaldehyde inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Lgals7 galectin 7 affects expression ISO o-Phthalaldehyde affects the expression of LGALS7 mRNA CTD PMID:22302311 NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015
JBrowse link
G Mki67 marker of proliferation Ki-67 affects expression ISO o-Phthalaldehyde affects the expression of MKI67 mRNA CTD PMID:22302311 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Nts neurotensin affects expression ISO o-Phthalaldehyde affects the expression of NTS mRNA CTD PMID:22302311 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423
JBrowse link
G Thbs1 thrombospondin 1 affects expression ISO o-Phthalaldehyde affects the expression of THBS1 mRNA CTD PMID:22302311 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thbs4 thrombospondin 4 affects expression ISO o-Phthalaldehyde affects the expression of THBS4 mRNA CTD PMID:22302311 NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
JBrowse link
G Timd2 T-cell immunoglobulin and mucin domain containing 2 affects expression ISO o-Phthalaldehyde affects the expression of TIMD2 mRNA CTD PMID:22302311 NCBI chr10:31,060,308...31,101,262
Ensembl chr10:31,060,326...31,094,623
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 affects expression ISO o-Phthalaldehyde affects the expression of TIMP1 mRNA CTD PMID:22302311 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tnf tumor necrosis factor increases expression ISO o-Phthalaldehyde results in increased expression of TNF mRNA CTD PMID:21785612 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 affects activity ISO o-Phthalaldehyde affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 affects expression ISO o-Phthalaldehyde affects the expression of TRPM6 mRNA CTD PMID:22302311 NCBI chr 1:216,136,407...216,320,523
Ensembl chr 1:216,170,038...216,320,520
JBrowse link
scalaradial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:7575673 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO scalaradial inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:8113982 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO scalaradial inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] CTD PMID:7575673 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:7575673 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    role 19894
      application 19729
        solvent 17050
          formic acid 9050
            formyl group 9012
              aldehyde 9012
                dialdehyde 140
                  (6E)-8-oxogeranial 0
                  2,5-diformylfuran 0
                  2,6,10-trimethyldodeca-2,4,6,8,10-pentaenedial 0
                  2,6-dimethyldeca-2,4,6,8-tetraenedial 0
                  2,6-dimethylocta-2,4,6-trienedial 0
                  4,4'-diapolycopenedial 0
                  4,9-dimethyldodeca-2,4,6,8,10-pentaenedial 0
                  4-methyl-1,4-dihydropyridine-3,5-dicarbaldehyde 0
                  4-methylocta-2,4,6-trienedial 0
                  aflatoxin B1 dialdehyde 0
                  aflatoxin B1 dialdehyde(1-) 0
                  bixin dialdehyde 0
                  botrydial 0
                  but-2-enedial + 9
                  crocetin dialdehyde 0
                  dolichodial 0
                  glutaraldehyde 12
                  glyoxal + 27
                  iridodial + 0
                  malonaldehyde 62
                  oleocanthal 0
                  oleuropein (dialdehyde form) 0
                  phthalaldehyde 47
                  scalaradial 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        carboacyl group 17727
                                          univalent carboacyl group 17727
                                            formyl group 9012
                                              aldehyde 9012
                                                dialdehyde 140
                                                  (6E)-8-oxogeranial 0
                                                  2,5-diformylfuran 0
                                                  2,6,10-trimethyldodeca-2,4,6,8,10-pentaenedial 0
                                                  2,6-dimethyldeca-2,4,6,8-tetraenedial 0
                                                  2,6-dimethylocta-2,4,6-trienedial 0
                                                  4,4'-diapolycopenedial 0
                                                  4,9-dimethyldodeca-2,4,6,8,10-pentaenedial 0
                                                  4-methyl-1,4-dihydropyridine-3,5-dicarbaldehyde 0
                                                  4-methylocta-2,4,6-trienedial 0
                                                  aflatoxin B1 dialdehyde 0
                                                  aflatoxin B1 dialdehyde(1-) 0
                                                  bixin dialdehyde 0
                                                  botrydial 0
                                                  but-2-enedial + 9
                                                  crocetin dialdehyde 0
                                                  dolichodial 0
                                                  glutaraldehyde 12
                                                  glyoxal + 27
                                                  iridodial + 0
                                                  malonaldehyde 62
                                                  oleocanthal 0
                                                  oleuropein (dialdehyde form) 0
                                                  phthalaldehyde 47
                                                  scalaradial 4
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