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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:but-2-enedial
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Accession:CHEBI:38123 term browser browse the term
Definition:A dialdehyde that has formula C4H4O2.
Synonyms:related_synonym: Formula=C4H4O2;   InChI=1S/C4H4O2/c5-3-1-2-4-6/h1-4H;   InChIKey=JGEMYUOFGVHXKV-UHFFFAOYSA-N;   SMILES=[H]C(=O)C([H])=C([H])C([H])=O
 xref: Beilstein:8391537



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fumaraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP 1-phenylimidazole inhibits the reaction [[[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde]; [[[CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde] which co-treated with Glutathione] results in increased glutathionylation of malealdehyde; [CYP2E1 protein results in increased oxidation of furan] which results in increased chemical synthesis of malealdehyde CTD PMID:21842885 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Fgf1 fibroblast growth factor 1 decreases secretion ISO FGF1 protein results in decreased secretion of malealdehyde CTD PMID:16222742 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO malealdehyde results in increased expression of GCLC mRNA CTD PMID:35750087 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects expression ISO malealdehyde affects the expression of GSTP1 mRNA CTD PMID:35750087 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Hdac2 histone deacetylase 2 affects expression ISO malealdehyde affects the expression of HDAC2 mRNA CTD PMID:35750087 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac8 histone deacetylase 8 increases expression ISO malealdehyde results in increased expression of HDAC8 mRNA CTD PMID:35750087 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923
JBrowse link
G Hdac9 histone deacetylase 9 affects expression ISO malealdehyde affects the expression of HDAC9 mRNA CTD PMID:35750087 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO malealdehyde results in decreased expression of TP53 mRNA CTD PMID:35750087 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Txn1 thioredoxin 1 decreases activity ISO malealdehyde results in decreased activity of TXN1 protein CTD PMID:27402187 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19834
    role 19810
      application 19653
        solvent 17022
          formic acid 9040
            formyl group 9002
              aldehyde 9002
                dialdehyde 140
                  but-2-enedial 9
                    fumaraldehyde 9
                    malealdehyde 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19834
    subatomic particle 19832
      composite particle 19832
        hadron 19832
          baryon 19832
            nucleon 19832
              atomic nucleus 19832
                atom 19832
                  main group element atom 19782
                    p-block element atom 19782
                      carbon group element atom 19730
                        carbon atom 19727
                          organic molecular entity 19727
                            organic group 18947
                              organic divalent group 18922
                                organodiyl group 18922
                                  carbonyl group 18879
                                    carbonyl compound 18879
                                      carboxylic acid 18605
                                        carboacyl group 17694
                                          univalent carboacyl group 17694
                                            formyl group 9002
                                              aldehyde 9002
                                                dialdehyde 140
                                                  but-2-enedial 9
                                                    fumaraldehyde 9
                                                    malealdehyde 0
paths to the root