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ONTOLOGY REPORT - ANNOTATIONS


Term:thiadiazoles
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Accession:CHEBI:38099 term browser browse the term
Synonyms:xref_mesh: MESH:D013830


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thiadiazoles term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lipa lipase A, lysosomal acid type JBrowse link 1 252,816,536 252,959,348 RGD:6480464
(S)-timolol (anhydrous) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6480464
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:6480464
G Aoc1 amine oxidase, copper containing 1 JBrowse link 4 78,496,043 78,515,582 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Rgs3 regulator of G-protein signaling 3 JBrowse link 5 78,429,017 78,567,281 RGD:6480464
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:6480464
acetazolamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:6480464
G Akap17a A-kinase anchoring protein 17A JBrowse link 12 18,527,116 18,531,780 RGD:6480464
G Akap9 A-kinase anchoring protein 9 JBrowse link 4 27,195,346 27,331,582 RGD:6480464
G Ammecr1l AMMECR1 like JBrowse link 18 24,539,530 24,563,576 RGD:6480464
G Anp32a acidic nuclear phosphoprotein 32 family member A JBrowse link 8 67,295,578 67,333,075 RGD:6480464
G Aqp1 aquaporin 1 (Colton blood group) JBrowse link 4 85,551,503 85,563,683 RGD:6480464
G Arhgap45 Rho GTPase activating protein 45 JBrowse link 7 12,541,032 12,741,314 RGD:6480464
G Arid2 AT-rich interaction domain 2 JBrowse link 7 137,680,564 137,798,329 RGD:6480464
G Brd4 bromodomain containing 4 JBrowse link 7 14,222,101 14,303,055 RGD:6480464
G Ca12 carbonic anhydrase 12 JBrowse link 8 72,405,770 72,461,425 RGD:6480464
G Ca13 carbonic anhydrase 13 JBrowse link 2 88,282,961 88,314,254 RGD:6480464
G Ca14 carbonic anhydrase 14 JBrowse link 2 198,010,142 198,017,635 RGD:6480464
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:6480464
G Ca4 carbonic anhydrase 4 JBrowse link 10 72,272,286 72,281,069 RGD:6480464
G Ca5a carbonic anhydrase 5A JBrowse link 19 54,731,829 54,761,697 RGD:6480464
G Ca5b carbonic anhydrase 5B JBrowse link X 32,232,106 32,291,124 RGD:6480464
G Ca6 carbonic anhydrase 6 JBrowse link 5 167,226,246 167,244,786 RGD:6480464
G Ca9 carbonic anhydrase 9 JBrowse link 5 59,008,277 59,015,535 RGD:6480464
G Car1 carbonic anhydrase 1 JBrowse link 2 88,185,204 88,227,486 RGD:6480464
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:6480464
G Car7 carbonic anhydrase 7 JBrowse link 19 636,545 645,935 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cbx3 chromobox 3 JBrowse link 4 81,243,809 81,257,898 RGD:6480464
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:6480464
G Cd47 Cd47 molecule JBrowse link 11 53,511,485 53,575,754 RGD:6480464
G Cirbp cold inducible RNA binding protein JBrowse link 7 12,400,066 12,405,054 RGD:6480464
G Clcn3 chloride voltage-gated channel 3 JBrowse link 16 32,448,821 32,520,649 RGD:6480464
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:6480464
G Ddx6 DEAD-box helicase 6 JBrowse link 8 48,924,768 48,961,394 RGD:6480464
G Dsc2 desmocollin 2 JBrowse link 18 11,826,705 11,858,801 RGD:6480464
G Glg1 golgi glycoprotein 1 JBrowse link 19 42,983,879 43,088,074 RGD:6480464
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:6480464
G Htra1 HtrA serine peptidase 1 JBrowse link 1 201,499,067 201,548,508 RGD:6480464
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:6480464
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 JBrowse link 4 180,423,452 180,800,088 RGD:6480464
G LOC102546572 zinc finger protein 709-like JBrowse link 7 15,015,985 15,038,622 RGD:6480464
G Mab21l2 mab-21 like 2 JBrowse link 2 185,849,749 185,852,833 RGD:6480464
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:6480464
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:6480464
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit JBrowse link 2 140,471,437 140,534,259 RGD:6480464
G Ndrg1 N-myc downstream regulated 1 JBrowse link 7 107,734,326 107,775,701 RGD:6480464
G Nrip1 nuclear receptor interacting protein 1 JBrowse link 11 14,658,225 14,742,478 RGD:6480464
G Peg3 paternally expressed 3 JBrowse link 1 70,210,810 70,237,450 RGD:6480464
G Pou2f1 POU class 2 homeobox 1 JBrowse link 13 84,075,316 84,217,368 RGD:6480464
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B JBrowse link 6 8,219,385 8,280,127 RGD:6480464
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:6480464
G Rbm39 RNA binding motif protein 39 JBrowse link 3 151,691,498 151,724,723 RGD:6480464
G Rbmx RNA binding motif protein, X-linked JBrowse link X 159,881,835 159,891,405 RGD:6480464
G Satb1 SATB homeobox 1 JBrowse link 9 2,181,135 2,277,949 RGD:6480464
G Sc5d sterol-C5-desaturase JBrowse link 8 46,525,406 46,537,014 RGD:6480464
G Schip1 schwannomin interacting protein 1 JBrowse link 2 172,312,290 173,087,236 RGD:6480464
G Sdc4 syndecan 4 JBrowse link 3 160,872,503 160,891,190 RGD:6480464
G Sema4b semaphorin 4B JBrowse link 1 141,986,145 142,014,400 RGD:6480464
G Sf3b1 splicing factor 3b, subunit 1 JBrowse link 9 61,594,620 61,634,510 RGD:6480464
G Sfmbt2 Scm-like with four mbt domains 2 JBrowse link 17 71,719,012 71,904,303 RGD:6480464
G Shox2 short stature homeobox 2 JBrowse link 2 164,118,175 164,126,783 RGD:6480464
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 JBrowse link 8 118,206,678 118,326,264 RGD:6480464
G Stx3 syntaxin 3 JBrowse link 1 228,137,781 228,195,004 RGD:6480464
G Styx serine/threonine/tyrosine interacting protein JBrowse link 15 19,690,079 19,720,683 RGD:6480464
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein JBrowse link 4 118,207,845 118,238,246 RGD:6480464
G Tmem30b transmembrane protein 30B JBrowse link 6 96,439,607 96,442,682 RGD:6480464
G Trim25 tripartite motif-containing 25 JBrowse link 10 76,343,847 76,362,159 RGD:6480464
G Umod uromodulin JBrowse link 1 189,186,027 189,199,939 RGD:6480464
G Wnk1 WNK lysine deficient protein kinase 1 JBrowse link 4 152,452,211 152,578,469 RGD:6480464
G Zfp322a zinc finger protein 322a JBrowse link 17 44,025,036 44,040,900 RGD:6480464
cefazolin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:6480464
G RT1-DOa RT1 class II, locus DOa JBrowse link 20 3,889,106 3,892,360 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464
G Slc25a20 solute carrier family 25 member 20 JBrowse link 8 117,455,308 117,476,762 RGD:6480464
flufenacet term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Tspo translocator protein JBrowse link 7 124,460,358 124,470,610 RGD:6480464
Methazolamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:6480464
G Car1 carbonic anhydrase 1 JBrowse link 2 88,185,204 88,227,486 RGD:6480464
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:6480464
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:6480464
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:6480464
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:6480464
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
methidathion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ca3 carbonic anhydrase 3 JBrowse link 2 88,126,519 88,136,063 RGD:6480464
G Car1 carbonic anhydrase 1 JBrowse link 2 88,185,204 88,227,486 RGD:6480464
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:6480464
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:6480464
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:6480464
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:6480464
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
xanomeline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrm1 cholinergic receptor, muscarinic 1 JBrowse link 1 224,869,087 224,885,101 RGD:6480464
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    chemical entity 19652
      atom 19650
        nonmetal atom 19516
          carbon atom 19405
            organic molecular entity 19405
              heteroorganic entity 18990
                organic heterocyclic compound 18151
                  organic heteromonocyclic compound 16250
                    thiadiazoles 90
                      (2R,3R,4S,5R)-5-(3,4-dichlorophenyl)-5'-methyl-1',3'-dioxo-4-\{[4-(1,2,3-thiadiazol-4-yl)phenyl]carbamoyl\}-1',3',4,5-tetrahydro-3H-spiro[furan-2,2'-indene]-3-carboxylic acid 0
                      (R)-1-amino-1-[5-(dimethylamino)-1,3,4-thiadiazol-2-yl]methanesulfonamide 0
                      1,2,3-Thiadiazole, 5-methyl- 0
                      1-(5-amino-1,3,4-thiadiazol-2-yl)-1,1-difluoromethanesulfonamide 0
                      1-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-3-[1,1,1-trifluoro-2-(trifluoromethyl)butan-2-yl]urea 0
                      1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-[1,1,1-trifluoro-2-(trifluoromethyl)butan-2-yl]urea 0
                      1-butyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-4-hydroxy-2-oxoquinoline-3-carboxamide 0
                      2,3,4,5,6-pentafluoro-N-methyl-N(alpha)-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]-L-phenylalaninamide 0
                      2-(acetylamino)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium 0
                      2-amino-5-ethyl-1,3,4-thiadiazole 0
                      3-(4-methyl-1,2,3-thiadiazolyl)-6-trichloromethyl[1,2,4]triazolo[3,4-b][1,3,4]thiadizole 0
                      5-(2-phenylethyl)-1,3,4-thiadiazol-2-amine 0
                      5-\{[(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino\}-1,3,4-thiadiazole-2-sulfonamide 0
                      5-amino-1,3,4-thiadiazole-2-sulfonamide 0
                      5-methoxy-1,3,4-thiadiazol-2(3H)-one + 1
                      ICPD-26 0
                      ICPD-47 0
                      Methazolamide 8
                      N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide 8
                      N-(4-methyl-5-thiadiazolyl)carbamic acid 2-methylpropyl ester 0
                      N-methyl-N(alpha)-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]-L-phenylalaninamide 0
                      acetazolamide + 65
                      benzyl \{(1R)-3-oxo-1-phenyl-3-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)amino]propyl\}carbamate 0
                      butazolamide 0
                      cefazedone 0
                      cefazolin 4
                      cefclidin 0
                      cefluprenam 0
                      cefozopran 0
                      ceftaroline + 0
                      ceftaroline fosamil + 0
                      ceftezole 0
                      ceftobiprole 0
                      ceftolozane 0
                      etridiazole 0
                      flufenacet 3
                      sulfamethizole 0
                      sulfametrole 0
                      thiadiazole + 74
                      thiadiazole antifungal agent + 0
                      thiadiazolecarboxylic acid + 0
                      tiadinil 0
                      timolol + 8
                      xanomeline 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  organic heteromonocyclic compound 16250
                                    thiadiazoles 90
                                      (2R,3R,4S,5R)-5-(3,4-dichlorophenyl)-5'-methyl-1',3'-dioxo-4-\{[4-(1,2,3-thiadiazol-4-yl)phenyl]carbamoyl\}-1',3',4,5-tetrahydro-3H-spiro[furan-2,2'-indene]-3-carboxylic acid 0
                                      (R)-1-amino-1-[5-(dimethylamino)-1,3,4-thiadiazol-2-yl]methanesulfonamide 0
                                      1,2,3-Thiadiazole, 5-methyl- 0
                                      1-(5-amino-1,3,4-thiadiazol-2-yl)-1,1-difluoromethanesulfonamide 0
                                      1-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-3-[1,1,1-trifluoro-2-(trifluoromethyl)butan-2-yl]urea 0
                                      1-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]-3-[1,1,1-trifluoro-2-(trifluoromethyl)butan-2-yl]urea 0
                                      1-butyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-4-hydroxy-2-oxoquinoline-3-carboxamide 0
                                      2,3,4,5,6-pentafluoro-N-methyl-N(alpha)-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]-L-phenylalaninamide 0
                                      2-(acetylamino)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-3-ium 0
                                      2-amino-5-ethyl-1,3,4-thiadiazole 0
                                      3-(4-methyl-1,2,3-thiadiazolyl)-6-trichloromethyl[1,2,4]triazolo[3,4-b][1,3,4]thiadizole 0
                                      5-(2-phenylethyl)-1,3,4-thiadiazol-2-amine 0
                                      5-\{[(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino\}-1,3,4-thiadiazole-2-sulfonamide 0
                                      5-amino-1,3,4-thiadiazole-2-sulfonamide 0
                                      5-methoxy-1,3,4-thiadiazol-2(3H)-one + 1
                                      ICPD-26 0
                                      ICPD-47 0
                                      Methazolamide 8
                                      N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2-ylidene)acetamide 8
                                      N-(4-methyl-5-thiadiazolyl)carbamic acid 2-methylpropyl ester 0
                                      N-methyl-N(alpha)-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)carbamoyl]-L-phenylalaninamide 0
                                      acetazolamide + 65
                                      benzyl \{(1R)-3-oxo-1-phenyl-3-[(5-sulfanyl-1,3,4-thiadiazol-2-yl)amino]propyl\}carbamate 0
                                      butazolamide 0
                                      cefazedone 0
                                      cefazolin 4
                                      cefclidin 0
                                      cefluprenam 0
                                      cefozopran 0
                                      ceftaroline + 0
                                      ceftaroline fosamil + 0
                                      ceftezole 0
                                      ceftobiprole 0
                                      ceftolozane 0
                                      etridiazole 0
                                      flufenacet 3
                                      sulfamethizole 0
                                      sulfametrole 0
                                      thiadiazole + 74
                                      thiadiazole antifungal agent + 0
                                      thiadiazolecarboxylic acid + 0
                                      tiadinil 0
                                      timolol + 8
                                      xanomeline 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.