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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
multiple interactions |
ISO |
[[ABCC1 gene mutant form results in increased susceptibility to Testosterone deficiency] which results in decreased hydroxylation of Testosterone] which results in decreased chemical synthesis of 15-hydroxytestosterone |
CTD |
PMID:22522787 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
andrastin A results in increased expression of and results in increased secretion of CSF2 protein |
CTD |
PMID:28535995 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
andrastin A results in increased expression of and results in increased secretion of TGFB1 protein |
CTD |
PMID:28535995 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
andrastin A results in increased expression of and results in increased secretion of TNF protein |
CTD |
PMID:28535995 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Cdh5 |
cadherin 5 |
multiple interactions |
ISO |
Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein] |
CTD |
PMID:31404653 |
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NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368
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G |
Etv2 |
ETS variant transcription factor 2 |
multiple interactions |
ISO |
Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
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NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431
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G |
Gata2 |
GATA binding protein 2 |
multiple interactions |
ISO |
Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in decreased expression of CDH5 protein]; Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
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NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
decreases expression |
ISO |
Digitonin results in decreased expression of HIF1A protein |
CTD |
PMID:34717917 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
Digitonin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
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NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
Spn |
sialophorin |
multiple interactions |
ISO |
Digitonin inhibits the reaction [[ETV2 protein co-treated with GATA2 protein] results in increased expression of SPN protein] |
CTD |
PMID:31404653 |
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NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
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