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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:38069 term browser browse the term
Definition:A chloro-1,3,5-triazine that is 2-chloro-1,3,5-triazine substituted by an ethyl amino and a (2-cyanopropan-2-yl)amino group at positions 6 and 4 respectively.
Synonyms:related_synonym: 2-([4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino)-2-methylpropanenitrile;   2-Chloro-4-(1-cyano-1-methylethylamino)-6-ethylamine-1,3,5-triazine;   2-[[4-chloro-6-(ethylamino)-s-triazin-2-yl]amino]-2-methylpropionitrile;   2-chloro-4-(1-cyano-1-methylethylamino)-6-ethylamino-1,3,5-triazine;   Bladex;   Formula=C9H13ClN6;   Fortrol;   InChI=1S/C9H13ClN6/c1-4-12-7-13-6(10)14-8(15-7)16-9(2,3)5-11/h4H2,1-3H3,(H2,12,13,14,15,16);   InChIKey=MZZBPDKVEFVLFF-UHFFFAOYSA-N;   SMILES=CCNc1nc(Cl)nc(NC(C)(C)C#N)n1
 alt_id: CHEBI:23421;   CHEBI:34658
 xref: Beilstein:615509;   CAS:21725-46-2;   KEGG:C14299
 xref_mesh: MESH:C007168
 xref: PMID:16882534;   PMID:23762632;   PMID:24607126;   PMID:24631619;   PPDB:185;   Pesticides:cyanazine;   Reaxys:615509;   UM-BBD_compID:c0176

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cyanazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A affects binding
affects activity
EXP cyanazine binds to ADRA2A protein
cyanazine affects the activity of ADRA2A protein
CTD PMID:11071396 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Dbh dopamine beta-hydroxylase increases expression EXP cyanazine results in increased expression of DBH protein CTD PMID:14550852 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Drd2 dopamine receptor D2 affects activity EXP cyanazine affects the activity of DRD2 protein CTD PMID:11071396 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO cyanazine binds to ESR1 protein
cyanazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]
CTD PMID:8858116 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 affects binding ISO cyanazine binds to ESR2 protein CTD PMID:12224631 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Pde4a phosphodiesterase 4A decreases activity ISO cyanazine results in decreased activity of PDE4A protein CTD PMID:21251949 NCBI chr 8:22,189,533...22,234,036
Ensembl chr 8:22,189,600...22,233,748
JBrowse link
G Pde5a phosphodiesterase 5A affects activity ISO cyanazine affects the activity of PDE5 protein CTD PMID:21251949 NCBI chr 2:226,899,604...227,044,916
Ensembl chr 2:226,900,619...227,041,576
JBrowse link
G Prl prolactin increases expression EXP cyanazine metabolite results in increased expression of PRL protein; cyanazine results in increased expression of PRL protein CTD PMID:11071396 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Th tyrosine hydroxylase increases expression EXP cyanazine results in increased expression of TH protein CTD PMID:14550852 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19720
      biological role 19720
        xenobiotic 18393
          cyanazine 9
            2-\{[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino\}-2-methylbutanenitrile + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    main group molecular entity 19662
                      s-block molecular entity 19429
                        hydrogen molecular entity 19423
                          hydrides 18758
                            inorganic hydride 17453
                              pnictogen hydride 17428
                                nitrogen hydride 17272
                                  azane 17003
                                    ammonia 17002
                                      organic amino compound 17001
                                        polyamine 8259
                                          diamine 8186
                                            diamino-1,3,5-triazine 3822
                                              1,3,5-triazinylamino nitrile 9
                                                cyanazine 9
                                                  2-\{[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino\}-2-methylbutanenitrile + 0
paths to the root