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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:38069 term browser browse the term
Definition:A chloro-1,3,5-triazine that is 2-chloro-1,3,5-triazine substituted by an ethyl amino and a (2-cyanopropan-2-yl)amino group at positions 6 and 4 respectively.
Synonyms:related_synonym: 2-([4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino)-2-methylpropanenitrile;   2-Chloro-4-(1-cyano-1-methylethylamino)-6-ethylamine-1,3,5-triazine;   2-[[4-chloro-6-(ethylamino)-s-triazin-2-yl]amino]-2-methylpropionitrile;   2-chloro-4-(1-cyano-1-methylethylamino)-6-ethylamino-1,3,5-triazine;   Bladex;   Formula=C9H13ClN6;   Fortrol;   InChI=1S/C9H13ClN6/c1-4-12-7-13-6(10)14-8(15-7)16-9(2,3)5-11/h4H2,1-3H3,(H2,12,13,14,15,16);   InChIKey=MZZBPDKVEFVLFF-UHFFFAOYSA-N;   SMILES=CCNc1nc(Cl)nc(NC(C)(C)C#N)n1
 alt_id: CHEBI:23421;   CHEBI:34658
 xref: Beilstein:615509;   CAS:21725-46-2;   KEGG:C14299
 xref_mesh: MESH:C007168
 xref: PMID:16882534;   PMID:23762632;   PMID:24607126;   PMID:24631619;   PPDB:185;   Pesticides:cyanazine;   Reaxys:615509;   UM-BBD_compID:c0176

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cyanazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A affects binding
affects activity
EXP cyanazine binds to ADRA2A protein
cyanazine affects the activity of ADRA2A protein
CTD PMID:11071396 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Dbh dopamine beta-hydroxylase increases expression EXP cyanazine results in increased expression of DBH protein CTD PMID:14550852 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Drd2 dopamine receptor D2 affects activity EXP cyanazine affects the activity of DRD2 protein CTD PMID:11071396 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO cyanazine binds to ESR1 protein
cyanazine inhibits the reaction [Estradiol binds to and results in increased activity of ESR1 protein]
CTD PMID:8858116 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 affects binding ISO cyanazine binds to ESR2 protein CTD PMID:12224631 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Pde4a phosphodiesterase 4A decreases activity ISO cyanazine results in decreased activity of PDE4A protein CTD PMID:21251949 NCBI chr 8:19,706,649...19,751,937
Ensembl chr 8:19,703,290...19,751,961
JBrowse link
G Pde5a phosphodiesterase 5A affects activity ISO cyanazine affects the activity of PDE5 protein CTD PMID:21251949 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Prl prolactin increases expression EXP cyanazine metabolite results in increased expression of PRL protein; cyanazine results in increased expression of PRL protein CTD PMID:11071396 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Th tyrosine hydroxylase increases expression EXP cyanazine results in increased expression of TH protein CTD PMID:14550852 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    role 20026
      biological role 20025
        xenobiotic 18703
          cyanazine 9
            2-\{[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino\}-2-methylbutanenitrile + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19974
                    main group molecular entity 19974
                      s-block molecular entity 19774
                        hydrogen molecular entity 19766
                          hydrides 19135
                            inorganic hydride 17930
                              pnictogen hydride 17913
                                nitrogen hydride 17801
                                  azane 17556
                                    ammonia 17555
                                      organic amino compound 17555
                                        polyamine 8331
                                          diamine 8260
                                            diamino-1,3,5-triazine 3835
                                              1,3,5-triazinylamino nitrile 9
                                                cyanazine 9
                                                  2-\{[4-chloro-6-(ethylamino)-1,3,5-triazin-2-yl]amino\}-2-methylbutanenitrile + 0
paths to the root