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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aminonaphthalene
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Accession:CHEBI:38034 term browser browse the term
Synonyms:related_synonym: aminonaphthalenes


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1-naphthylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO 1-Naphthylamine binds to and results in increased activity of AHR protein CTD PMID:11790108 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Fam83b family with sequence similarity 83, member B affects response to substance ISO FAM83B gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr 8:83,616,148...83,693,484
Ensembl chr 8:83,613,023...83,693,472
JBrowse link
G Npas3 neuronal PAS domain protein 3 affects response to substance ISO NPAS3 gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr 6:74,081,995...74,913,025 JBrowse link
G Tmem132d transmembrane protein 132D affects response to substance ISO TMEM132D gene SNP affects the susceptibility to 1-Naphthylamine CTD PMID:25622337 NCBI chr12:31,934,343...32,607,768
Ensembl chr12:31,934,343...32,607,370
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO 1-Naphthylamine results in decreased activity of UGT1A9 protein CTD PMID:14744740 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
2-naphthylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatk apoptosis-associated tyrosine kinase increases expression ISO 2-Naphthylamine results in increased expression of AATK mRNA CTD PMID:18247414 NCBI chr10:109,184,338...109,224,455
Ensembl chr10:109,188,112...109,224,370
JBrowse link
G Amhr2 anti-Mullerian hormone receptor type 2 decreases expression ISO 2-Naphthylamine results in decreased expression of AMHR2 mRNA CTD PMID:18247414 NCBI chr 7:144,052,202...144,060,678
Ensembl chr 7:144,052,061...144,060,685
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO 2-Naphthylamine results in decreased expression of BAD mRNA CTD PMID:18247414 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO 2-Naphthylamine results in increased expression of BCL2A1 mRNA CTD PMID:18247414 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO 2-Naphthylamine results in decreased expression of BRCA1 mRNA CTD PMID:18247414 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Btf3 basic transcription factor 3 decreases expression ISO 2-Naphthylamine results in decreased expression of BTF3 mRNA CTD PMID:18247414 NCBI chr 2:28,417,316...28,424,436
Ensembl chr 2:28,417,579...28,423,762
JBrowse link
G Btk Bruton tyrosine kinase increases expression ISO 2-Naphthylamine results in increased expression of BTK mRNA CTD PMID:18247414 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580
JBrowse link
G C5ar1 complement C5a receptor 1 decreases expression ISO 2-Naphthylamine results in decreased expression of C5AR1 mRNA CTD PMID:18247414 NCBI chr 1:78,186,777...78,195,132
Ensembl chr 1:78,186,776...78,195,328
JBrowse link
G Cartpt CART prepropeptide increases expression ISO 2-Naphthylamine results in increased expression of CARTPT mRNA CTD PMID:18247414 NCBI chr 2:30,125,249...30,127,408
Ensembl chr 2:30,125,249...30,127,269
JBrowse link
G Cbl Cbl proto-oncogene increases expression ISO 2-Naphthylamine results in increased expression of CBL mRNA CTD PMID:18247414 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO 2-Naphthylamine results in increased expression of CCL5 mRNA CTD PMID:18247414 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO 2-Naphthylamine results in increased expression of CCR5 mRNA CTD PMID:18247414 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 decreases expression ISO 2-Naphthylamine results in decreased expression of CCR6 mRNA CTD PMID:18247414 NCBI chr 1:53,063,380...53,087,519
Ensembl chr 1:53,065,025...53,087,474
JBrowse link
G Cd4 Cd4 molecule increases expression ISO 2-Naphthylamine results in increased expression of CD4 mRNA CTD PMID:18247414 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd59 CD59 molecule increases expression ISO 2-Naphthylamine results in increased expression of CD59 mRNA CTD PMID:18247414 NCBI chr 3:94,010,481...94,028,660
Ensembl chr 3:94,010,475...94,028,621
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression ISO 2-Naphthylamine results in decreased expression of CKS1B mRNA CTD PMID:18247414 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases expression ISO 2-Naphthylamine results in decreased expression of CREB1 mRNA CTD PMID:18247414 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression ISO 2-Naphthylamine results in decreased expression of CXCL2 mRNA CTD PMID:18247414 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 decreases expression ISO 2-Naphthylamine results in decreased expression of CXCR2 mRNA CTD PMID:18247414 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO 2-Naphthylamine results in increased expression of CYP1A1 mRNA
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [2-Naphthylamine results in increased expression of CYP1A1 mRNA]
CTD PMID:25224404 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity ISO CYP1A2 protein results in increased activity of 2-Naphthylamine CTD PMID:15450435 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 increases reduction ISO CYP2S1 protein results in increased reduction of 2-Naphthylamine analog CTD PMID:23682735 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 increases metabolic processing ISO
EXP
CYP4B1 protein results in increased metabolism of 2-Naphthylamine CTD PMID:9310344 NCBI chr 5:134,508,728...134,526,103
Ensembl chr 5:134,508,730...134,526,089
JBrowse link
G Dedd death effector domain-containing increases expression ISO 2-Naphthylamine results in increased expression of DEDD mRNA CTD PMID:18247414 NCBI chr13:89,706,932...89,721,825
Ensembl chr13:89,718,066...89,721,454
JBrowse link
G Dffb DNA fragmentation factor subunit beta decreases expression ISO 2-Naphthylamine results in decreased expression of DFFB mRNA CTD PMID:18247414 NCBI chr 5:171,250,559...171,261,875
Ensembl chr 5:171,249,633...171,262,119
JBrowse link
G Dnase2 deoxyribonuclease 2, lysosomal decreases expression ISO 2-Naphthylamine results in decreased expression of DNASE2 mRNA CTD PMID:18247414 NCBI chr19:26,022,855...26,025,523
Ensembl chr19:26,022,849...26,025,532
JBrowse link
G Ednra endothelin receptor type A decreases expression ISO 2-Naphthylamine results in decreased expression of EDNRA mRNA CTD PMID:18247414 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Enpep glutamyl aminopeptidase increases metabolic processing ISO
EXP
ENPEP protein results in increased metabolism of 2-Naphthylamine analog CTD PMID:11732752 NCBI chr 2:233,667,253...233,743,866
Ensembl chr 2:233,667,254...233,743,866
JBrowse link
G Epha3 Eph receptor A3 decreases expression ISO 2-Naphthylamine results in decreased expression of EPHA3 mRNA CTD PMID:18247414 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Ephb3 Eph receptor B3 increases expression ISO 2-Naphthylamine results in increased expression of EPHB3 mRNA CTD PMID:18247414 NCBI chr11:83,527,960...83,546,742
Ensembl chr11:83,527,962...83,546,674
JBrowse link
G Epo erythropoietin increases expression ISO 2-Naphthylamine results in increased expression of EPO mRNA CTD PMID:18247414 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Ezr ezrin increases expression ISO 2-Naphthylamine results in increased expression of EZR mRNA CTD PMID:18247414 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Faslg Fas ligand decreases expression ISO 2-Naphthylamine results in decreased expression of FASLG mRNA CTD PMID:18247414 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Flt3 Fms related receptor tyrosine kinase 3 decreases expression ISO 2-Naphthylamine results in decreased expression of FLT3 mRNA CTD PMID:18247414 NCBI chr12:9,360,439...9,437,004
Ensembl chr12:9,360,672...9,436,570
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO 2-Naphthylamine results in decreased expression of FN1 mRNA CTD PMID:18247414 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression ISO 2-Naphthylamine results in increased expression of SNL mRNA CTD PMID:18247414 NCBI chr12:13,655,459...13,668,595
Ensembl chr12:13,656,554...13,668,515
JBrowse link
G Gdf1 growth differentiation factor 1 increases expression ISO 2-Naphthylamine results in increased expression of GDF1 mRNA CTD PMID:18247414 NCBI chr16:20,845,580...20,860,789
Ensembl chr16:20,845,576...20,860,767
JBrowse link
G Hltf helicase-like transcription factor decreases expression ISO 2-Naphthylamine results in decreased expression of HLTF mRNA CTD PMID:18247414 NCBI chr 2:104,854,571...104,914,338
Ensembl chr 2:104,854,572...104,914,173
JBrowse link
G Ifnar1 interferon alpha and beta receptor subunit 1 decreases expression ISO 2-Naphthylamine results in decreased expression of IFNAR1 mRNA CTD PMID:18247414 NCBI chr11:31,640,407...31,666,839
Ensembl chr11:31,640,407...31,664,061
JBrowse link
G Il10 interleukin 10 decreases expression ISO 2-Naphthylamine results in decreased expression of IL10 mRNA CTD PMID:18247414 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il3ra interleukin 3 receptor subunit alpha decreases expression ISO 2-Naphthylamine results in decreased expression of IL3RA mRNA CTD PMID:18247414 NCBI chr12:18,534,762...18,542,508
Ensembl chr12:18,534,767...18,540,166
JBrowse link
G Il9 interleukin 9 decreases expression ISO 2-Naphthylamine results in decreased expression of IL9 mRNA CTD PMID:18247414 NCBI chr17:8,558,827...8,561,950
Ensembl chr17:8,558,827...8,561,950
JBrowse link
G Itgal integrin subunit alpha L decreases expression ISO 2-Naphthylamine results in decreased expression of ITGAL mRNA CTD PMID:18247414 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
JBrowse link
G Klf11 Kruppel-like factor 11 increases expression ISO 2-Naphthylamine results in increased expression of KLF11 mRNA CTD PMID:18247414 NCBI chr 6:43,829,812...43,841,649
Ensembl chr 6:43,829,945...43,841,651
JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase increases metabolic processing ISO
EXP
LNPEP protein results in increased metabolism of 2-Naphthylamine analog CTD PMID:11732752 NCBI chr 1:59,289,392...59,384,540
Ensembl chr 1:59,297,294...59,347,472
Ensembl chr 1:59,297,294...59,347,472
JBrowse link
G Ltb lymphotoxin beta decreases expression ISO 2-Naphthylamine results in decreased expression of LTB mRNA CTD PMID:18247414 NCBI chr20:5,184,631...5,186,476
Ensembl chr20:5,184,515...5,186,503
JBrowse link
G Madd MAP-kinase activating death domain increases expression ISO 2-Naphthylamine results in increased expression of MADD mRNA CTD PMID:18247414 NCBI chr 3:79,960,301...80,003,023
Ensembl chr 3:79,960,301...80,003,032
JBrowse link
G Mpo myeloperoxidase affects metabolic processing ISO MPO protein affects the metabolism of 2-Naphthylamine CTD PMID:9288889 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mst1 macrophage stimulating 1 decreases expression ISO 2-Naphthylamine results in decreased expression of MST1 mRNA CTD PMID:18247414 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Nat1 N-acetyltransferase 1 increases activity ISO NAT1 protein results in increased activity of 2-Naphthylamine CTD PMID:15450435 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nat2 N-acetyltransferase 2 increases activity ISO NAT2 protein results in increased activity of 2-Naphthylamine CTD PMID:15450435 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Nfkbie NFKB inhibitor epsilon decreases expression ISO 2-Naphthylamine results in decreased expression of NFKBIE mRNA CTD PMID:18247414 NCBI chr 9:17,828,405...17,835,240
Ensembl chr 9:17,828,408...17,835,240
JBrowse link
G Nfyb nuclear transcription factor Y subunit beta decreases expression ISO 2-Naphthylamine results in decreased expression of NFYB mRNA CTD PMID:18247414 NCBI chr 7:27,081,667...27,097,481
Ensembl chr 7:27,081,667...27,097,479
JBrowse link
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 decreases expression ISO 2-Naphthylamine results in decreased expression of NME3 mRNA CTD PMID:18247414 NCBI chr10:14,258,232...14,259,365
Ensembl chr10:14,258,380...14,259,336
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO 2-Naphthylamine results in increased expression of NOS2 mRNA CTD PMID:18247414 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npy5r neuropeptide Y receptor Y5 multiple interactions
affects binding
ISO 2-Naphthylamine analog binds to and results in decreased activity of NPY5R protein
2-Naphthylamine analog binds to NPY5R protein
CTD PMID:10937714 NCBI chr16:24,796,685...24,805,730
Ensembl chr16:24,797,124...24,805,079
JBrowse link
G Oprk1 opioid receptor, kappa 1 decreases expression ISO 2-Naphthylamine results in decreased expression of OPRK1 mRNA CTD PMID:18247414 NCBI chr 5:13,742,655...13,760,460
Ensembl chr 5:13,744,658...13,760,305
JBrowse link
G Pld1 phospholipase D1 decreases expression ISO 2-Naphthylamine results in decreased expression of PLD1 mRNA CTD PMID:18247414 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Pld2 phospholipase D2 increases expression ISO 2-Naphthylamine results in increased expression of PLD2 mRNA CTD PMID:18247414 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Pou2af1 POU class 2 homeobox associating factor 1 decreases expression ISO 2-Naphthylamine results in decreased expression of POU2AF1 mRNA CTD PMID:18247414 NCBI chr 8:55,603,968...55,631,448
Ensembl chr 8:55,603,968...55,631,446
JBrowse link
G Pou2f1 POU class 2 homeobox 1 increases expression ISO 2-Naphthylamine results in increased expression of POU2F1 mRNA CTD PMID:18247414 NCBI chr13:84,075,316...84,217,368
Ensembl chr13:84,083,632...84,217,366
JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta increases expression ISO 2-Naphthylamine results in increased expression of PRKAR2B mRNA CTD PMID:18247414 NCBI chr 6:51,265,509...51,356,383
Ensembl chr 6:51,265,515...51,356,383
JBrowse link
G Psmb6 proteasome 20S subunit beta 6 decreases expression ISO 2-Naphthylamine results in decreased expression of PSMB6 mRNA CTD PMID:18247414 NCBI chr10:57,131,339...57,133,685
Ensembl chr10:57,131,386...57,133,637
JBrowse link
G Ptafr platelet-activating factor receptor decreases expression ISO 2-Naphthylamine results in decreased expression of PTAFR mRNA CTD PMID:18247414 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Ptx3 pentraxin 3 decreases expression ISO 2-Naphthylamine results in decreased expression of PTX3 mRNA CTD PMID:18247414 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
G Rarg retinoic acid receptor, gamma decreases expression ISO 2-Naphthylamine results in decreased expression of RARG mRNA CTD PMID:18247414 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186
JBrowse link
G Rgs1 regulator of G-protein signaling 1 increases expression ISO 2-Naphthylamine results in increased expression of RGS1 mRNA CTD PMID:18247414 NCBI chr13:61,066,196...61,070,772
Ensembl chr13:61,066,153...61,070,599
JBrowse link
G Rnpep arginyl aminopeptidase increases metabolic processing EXP
ISO
RNPEP protein results in increased metabolism of 2-Naphthylamine analog CTD PMID:11732752 NCBI chr13:52,092,863...52,124,006
Ensembl chr13:52,092,859...52,111,363
JBrowse link
G Rpl7a ribosomal protein L7a decreases expression ISO 2-Naphthylamine results in decreased expression of RPL7A mRNA CTD PMID:18247414 NCBI chr 3:5,458,985...5,461,627
Ensembl chr 3:5,459,160...5,461,583
Ensembl chr 3:5,459,160...5,461,583
JBrowse link
G Rps25 ribosomal protein s25 increases expression ISO 2-Naphthylamine results in increased expression of RPS25 mRNA CTD PMID:18247414 NCBI chr 8:48,727,346...48,729,722
Ensembl chr 8:48,727,618...48,729,580
JBrowse link
G Runx1t1 RUNX1 partner transcriptional co-repressor 1 decreases expression ISO 2-Naphthylamine results in decreased expression of RUNX1T1 mRNA CTD PMID:18247414 NCBI chr 5:27,284,921...27,440,802
Ensembl chr 5:27,312,928...27,442,841
JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression ISO 2-Naphthylamine results in increased expression of S100A10 mRNA CTD PMID:18247414 NCBI chr 2:193,892,589...193,901,236
Ensembl chr 2:193,892,589...193,901,236
JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 decreases expression ISO 2-Naphthylamine results in decreased expression of SLC9A3R2 mRNA CTD PMID:18247414 NCBI chr10:14,003,330...14,015,066
Ensembl chr10:14,003,320...14,013,870
JBrowse link
G Smad9 SMAD family member 9 increases expression ISO 2-Naphthylamine results in increased expression of SMAD9 mRNA CTD PMID:18247414 NCBI chr 2:143,951,725...144,002,025
Ensembl chr 2:144,191,846...144,212,138
Ensembl chr 2:144,191,846...144,212,138
JBrowse link
G Snca synuclein alpha increases expression ISO 2-Naphthylamine results in increased expression of SNCA mRNA CTD PMID:18247414 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO 2-Naphthylamine results in decreased expression of SREBF1 mRNA CTD PMID:18247414 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Stat2 signal transducer and activator of transcription 2 decreases expression ISO 2-Naphthylamine results in decreased expression of STAT2 mRNA CTD PMID:18247414 NCBI chr 7:2,691,064...2,707,530
Ensembl chr 7:2,691,369...2,707,741
JBrowse link
G Stk25 serine/threonine kinase 25 increases expression ISO 2-Naphthylamine results in increased expression of STK25 mRNA CTD PMID:18247414 NCBI chr 9:100,767,578...100,779,715
Ensembl chr 9:100,767,579...100,779,715
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 increases sulfation ISO SULT1A1 protein results in increased sulfation of 2-Naphthylamine CTD PMID:17433394 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a increases sulfation ISO SULT1C2 protein results in increased sulfation of 2-Naphthylamine CTD PMID:17433394 NCBI chr 9:4,152,588...4,168,355
Ensembl chr 9:4,152,589...4,168,221
JBrowse link
G Sult4a1 sulfotransferase family 4A, member 1 increases metabolic processing ISO SULT4A1 protein results in increased metabolism of 2-Naphthylamine CTD PMID:12039030 NCBI chr 7:124,958,546...124,982,602
Ensembl chr 7:124,958,546...124,982,566
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit increases expression ISO 2-Naphthylamine results in increased expression of SUPT4H1 mRNA CTD PMID:18247414 NCBI chr10:75,032,365...75,038,547
Ensembl chr10:75,032,365...75,038,547
JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression ISO 2-Naphthylamine results in decreased expression of TFDP1 mRNA CTD PMID:18247414 NCBI chr16:81,088,642...81,127,244
Ensembl chr16:81,089,292...81,127,257
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A decreases expression ISO 2-Naphthylamine results in decreased expression of TNFRSF1A mRNA CTD PMID:18247414 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO 2-Naphthylamine results in decreased expression of TP53 mRNA CTD PMID:18247414 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression ISO 2-Naphthylamine results in increased expression of TSHR mRNA CTD PMID:18247414 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I increases expression ISO 2-Naphthylamine results in increased expression of UBE2I mRNA CTD PMID:18247414 NCBI chr10:14,618,615...14,639,274
Ensembl chr10:14,620,531...14,630,151
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 increases expression ISO 2-Naphthylamine results in increased expression of UGP2 mRNA CTD PMID:18247414 NCBI chr14:106,208,174...106,249,322
Ensembl chr14:106,208,176...106,248,539
JBrowse link
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 decreases expression ISO 2-Naphthylamine results in decreased expression of UQCRFS1 mRNA CTD PMID:18247414 NCBI chr17:35,677,984...35,682,262
Ensembl chr17:35,677,984...35,682,259
JBrowse link
G Vim vimentin decreases expression ISO 2-Naphthylamine results in decreased expression of VIM mRNA CTD PMID:18247414 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
2-propionyl-6-dimethylaminonaphthalene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin multiple interactions
affects binding
ISO Guanidine inhibits the reaction [prodan binds to ALB protein]; prodan inhibits the reaction [Warfarin binds to ALB protein] CTD PMID:12044178, PMID:15328891, PMID:15353599 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
8-anilinonaphthalene-1-sulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambp alpha-1-microglobulin/bikunin precursor affects binding ISO 1-anilino-8-naphthalenesulfonate binds to AMBP protein CTD PMID:16461020 NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
JBrowse link
G Apod apolipoprotein D affects binding ISO 1-anilino-8-naphthalenesulfonate binds to APOD protein CTD PMID:16461020 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G C8g complement C8 gamma chain affects binding ISO 1-anilino-8-naphthalenesulfonate binds to C8G protein CTD PMID:16461020 NCBI chr 3:2,724,616...2,727,616
Ensembl chr 3:2,724,616...2,727,616
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 affects binding ISO 1-anilino-8-naphthalenesulfonate binds to GSTA1 protein CTD PMID:14690442 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Lcn1 lipocalin 1 affects binding ISO 1-anilino-8-naphthalenesulfonate binds to LCN1 protein CTD PMID:16461020 NCBI chr 3:4,233,111...4,236,960
Ensembl chr 3:4,233,111...4,236,960
JBrowse link
G Lcn2 lipocalin 2 affects binding ISO 1-anilino-8-naphthalenesulfonate binds to LCN2 protein CTD PMID:16461020 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Obp2a odorant binding protein 2A affects binding ISO 1-anilino-8-naphthalenesulfonate binds to OBP2A protein CTD PMID:16461020 NCBI chr 3:2,908,684...2,913,362
Ensembl chr 3:2,910,083...2,913,362
JBrowse link
G Orm1 orosomucoid 1 affects binding ISO 1-anilino-8-naphthalenesulfonate binds to ORM1 protein CTD PMID:16461020 NCBI chr 5:79,179,668...79,182,820
Ensembl chr 5:79,179,417...79,182,820
JBrowse link
G Paep progestagen associated endometrial protein affects binding ISO 1-anilino-8-naphthalenesulfonate binds to PAEP protein CTD PMID:16461020 NCBI chr 3:2,935,396...2,938,883 JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO 1-anilino-8-naphthalenesulfonate binds to PTGDS protein CTD PMID:16461020 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ttr transthyretin affects binding
multiple interactions
ISO 1-anilino-8-naphthalenesulfonate binds to TTR protein
3,3'-dichlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 3,4-dichlorinated biphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; 4-chlorobiphenyl metabolite inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]; Thyroxine inhibits the reaction [1-anilino-8-naphthalenesulfonate binds to TTR protein]
CTD PMID:23584369 NCBI chr18:15,532,963...15,542,180
Ensembl chr18:15,532,963...15,540,177
JBrowse link
cascade blue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions
increases uptake
ISO Bleomycin inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Capecitabine inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Docetaxel inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Etoposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Irinotecan inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Methotrexate inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Tamoxifen inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Teniposide inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue]; Thiotepa inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
glycyl-L-phenylalanine 2-naphthylamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 multiple interactions ISO 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]; NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
monodansylcadaverine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO monodansylcadaverine results in decreased phosphorylation of AKT1 protein CTD PMID:16170020 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO monodansylcadaverine results in decreased expression of BAD protein CTD PMID:16170020 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO monodansylcadaverine results in increased expression of BCL2L11 protein CTD PMID:16170020 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO monodansylcadaverine results in decreased expression of BIRC5 protein CTD PMID:16170020 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Ccl25 C-C motif chemokine ligand 25 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL25 protein] CTD PMID:22341560 NCBI chr12:2,429,492...2,438,928
Ensembl chr12:2,429,509...2,438,817
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL5 protein] CTD PMID:22341560 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL12 protein] CTD PMID:22341560 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression ISO monodansylcadaverine results in decreased expression of GSK3B protein CTD PMID:16170020 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein]; monodansylcadaverine inhibits the reaction [IGF1 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:20733350 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il12b interleukin 12B multiple interactions ISO monodansylcadaverine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL12B protein] CTD PMID:22341560 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il2 interleukin 2 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL2 protein] CTD PMID:22341560 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il3 interleukin 3 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL3 protein] CTD PMID:22341560 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il4 interleukin 4 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL4 protein] CTD PMID:22341560 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] CTD PMID:22341560 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased degradation of IRF3 protein] CTD PMID:22341560 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:22341560 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:22341560 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein] CTD PMID:22341560 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of NFKB1 protein] CTD PMID:22341560 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Tgm2 transglutaminase 2 decreases activity ISO monodansylcadaverine results in decreased activity of TGM2 protein CTD PMID:16382148 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TICAM2 mRNA] CTD PMID:22341560 NCBI chr18:40,555,106...40,572,569
Ensembl chr18:40,555,106...40,572,241
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TIMP1 protein] CTD PMID:22341560 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TIMP4 protein] CTD PMID:22341560 NCBI chr 4:147,156,948...147,163,467
Ensembl chr 4:147,156,948...147,163,467
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of TLR4 protein] CTD PMID:22341560 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNFRSF1A protein] CTD PMID:22341560 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Zfp143 zinc finger protein 143 multiple interactions ISO monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein] CTD PMID:20733350 NCBI chr 1:174,702,310...174,738,133
Ensembl chr 1:174,702,373...174,738,126
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        refrigerant 17418
          ammonia 16939
            organic amino compound 16938
              aromatic amine 13616
                aminonaphthalene 132
                  2-acyl-6-dimethylaminonaphthalene + 1
                  4-amino-3-hydroxynaphthalene-1-sulfonic acid 0
                  6-amino-1,2-dihydroxynaphthalene 0
                  6-dimethylamino-2-naphthoic acid + 0
                  8-Phenylamino-naphthalene-1-sulfonic acid anion 0
                  8-anilinonaphthalene-1-sulfonic acid 11
                  Evans blue free acid 0
                  HA15 0
                  aminonaphthalenesulfonic acid + 0
                  cascade blue 1
                  dansyl chloride + 0
                  monodansylcadaverine 26
                  naphthylamine + 96
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    main group molecular entity 19670
                      s-block molecular entity 19428
                        hydrogen molecular entity 19418
                          hydrides 18685
                            inorganic hydride 17409
                              pnictogen hydride 17381
                                nitrogen hydride 17223
                                  azane 16940
                                    ammonia 16939
                                      organic amino compound 16938
                                        aromatic amine 13616
                                          aminonaphthalene 132
                                            2-acyl-6-dimethylaminonaphthalene + 1
                                            4-amino-3-hydroxynaphthalene-1-sulfonic acid 0
                                            6-amino-1,2-dihydroxynaphthalene 0
                                            6-dimethylamino-2-naphthoic acid + 0
                                            8-Phenylamino-naphthalene-1-sulfonic acid anion 0
                                            8-anilinonaphthalene-1-sulfonic acid 11
                                            Evans blue free acid 0
                                            HA15 0
                                            aminonaphthalenesulfonic acid + 0
                                            cascade blue 1
                                            dansyl chloride + 0
                                            monodansylcadaverine 26
                                            naphthylamine + 96
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.